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PRJEB1986: zebrafish developmental stages transcriptome

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Results for irf10+irf8+irf9

Z-value: 0.87

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Transcription factors associated with irf10+irf8+irf9

Gene Symbol Gene ID Gene Info
ENSDARG00000016457 interferon regulatory factor 9
ENSDARG00000027658 interferon regulatory factor 10
ENSDARG00000056407 interferon regulatory factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf8dr11_v1_chr18_+_30567945_305679450.522.1e-02Click!
irf9dr11_v1_chr12_+_13282797_132828070.361.3e-01Click!
irf10dr11_v1_chr23_+_642001_6420520.262.9e-01Click!

Activity profile of irf10+irf8+irf9 motif

Sorted Z-values of irf10+irf8+irf9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_38662125 1.31 ENSDART00000136949
si:dkey-58f10.13
chr19_-_7115229 1.11 ENSDART00000001930
proteasome subunit beta 13a
chr15_-_17071328 1.02 ENSDART00000122617
si:ch211-24o10.6
chr19_+_7115223 1.00 ENSDART00000001359
proteasome subunit beta 12
chr11_-_20096018 0.96 ENSDART00000030420
opioid growth factor receptor-like 2
chr4_-_12795030 0.87 ENSDART00000150427
beta-2-microglobulin
chr15_-_43625549 0.85 ENSDART00000168589
cathepsin C
chr21_-_22648007 0.79 ENSDART00000121788
grass carp reovirus (GCRV)-induced gene 2l
chr16_+_29509133 0.78 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr18_+_26422124 0.76 ENSDART00000060245
cathepsin H
chr1_-_7930679 0.67 ENSDART00000146090
si:dkey-79f11.10
chr10_+_17776981 0.66 ENSDART00000141693
chemokine (C-C motif) ligand 19b
chr13_-_37642890 0.64 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
chr9_-_18215644 0.64 ENSDART00000145876
epithelial stromal interaction 1
chr3_+_29941777 0.63 ENSDART00000113889
interferon-induced protein 35
chr19_-_7110617 0.62 ENSDART00000104838
proteasome subunit beta 8A
chr15_+_24588963 0.60 ENSDART00000155075
zgc:198241
chr4_-_17669881 0.59 ENSDART00000066997
DNA-damage regulated autophagy modulator 1
chr15_+_2421729 0.57 ENSDART00000082294
ENSDART00000156428
hephaestin-like 1a
chr3_+_8826905 0.57 ENSDART00000167474
ENSDART00000168088
si:dkeyp-30d6.2
chr16_+_48678655 0.55 ENSDART00000150156
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_-_36127234 0.54 ENSDART00000130917
coilin p80
chr15_+_2421432 0.53 ENSDART00000193772
hephaestin-like 1a
chr15_-_15227541 0.52 ENSDART00000184787
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr22_-_17499513 0.52 ENSDART00000105460
si:ch211-197g15.6
chr9_+_23765587 0.51 ENSDART00000145120
si:ch211-219a4.3
chr15_-_29162193 0.51 ENSDART00000138449
ENSDART00000099885
XIAP associated factor 1
chr16_+_29514473 0.50 ENSDART00000034102
cathepsin S, ortholog 2, tandem duplicate 2
chr8_-_27656765 0.49 ENSDART00000078491
Moloney leukemia virus 10b, tandem duplicate 2
chr12_-_35936329 0.47 ENSDART00000166634
ring finger protein 213b
chr13_-_37631092 0.46 ENSDART00000108855
si:dkey-188i13.7
chr3_+_52092599 0.45 ENSDART00000104648
zgc:165582
chr1_-_47161996 0.45 ENSDART00000053153
major histocompatibility complex class I ZBA
chr1_+_58424507 0.44 ENSDART00000114197
si:ch73-236c18.3
chr11_-_19775182 0.44 ENSDART00000037894
nicotinamide phosphoribosyltransferase b
chr25_+_14092871 0.43 ENSDART00000067239
guanylate cyclase activator 1g
chr5_+_38619813 0.42 ENSDART00000133314
si:ch211-271e10.3
chr15_-_36369743 0.42 ENSDART00000155942
si:dkey-23k10.3
chr4_-_26107841 0.41 ENSDART00000172012
si:ch211-244b2.4
chr2_-_42035250 0.41 ENSDART00000056460
ENSDART00000140788
guanylate binding protein 1
chr4_-_76383223 0.40 ENSDART00000161866
ENSDART00000168456
ENSDART00000174287
ENSDART00000174048
zgc:123107
chr22_-_5958066 0.40 ENSDART00000145821
si:rp71-36a1.3
chr1_-_7951002 0.40 ENSDART00000138187
si:dkey-79f11.8
chr10_+_31809226 0.40 ENSDART00000087898
forkhead box O1 b
chr4_-_26108053 0.39 ENSDART00000066951
si:ch211-244b2.4
chr24_+_12945803 0.39 ENSDART00000005105
proteasome activator subunit 1
chr10_+_26689262 0.38 ENSDART00000123195
ENSDART00000132946
teleost multiple tissue opsin 3b
chr2_-_38363017 0.38 ENSDART00000088026
protein arginine methyltransferase 5
chr15_+_24572926 0.37 ENSDART00000155636
ENSDART00000187800
dehydrogenase/reductase (SDR family) member 13b
chr6_+_52947699 0.37 ENSDART00000180913
ubiquitin-like modifier activating enzyme 7
chr2_-_47904043 0.36 ENSDART00000185328
ENSDART00000126740
finTRIM family, member 22
chr13_-_37608441 0.36 ENSDART00000140230
zgc:123068
chr10_+_26645953 0.35 ENSDART00000131482
adhesion G protein-coupled receptor G4b
chr21_-_22676323 0.34 ENSDART00000167392
grass carp reovirus (GCRV)-induced gene 2h
chr22_+_36902352 0.34 ENSDART00000036273
tripartite motif containing 35-20
chr22_+_8800432 0.33 ENSDART00000139940
si:dkey-182g1.6
chr7_+_19615056 0.33 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
chr7_-_19614916 0.33 ENSDART00000169029
zgc:194655
chr3_+_1942219 0.33 ENSDART00000114520
zgc:165583
chr8_+_43016714 0.32 ENSDART00000142671
Ras association (RalGDS/AF-6) domain family member 2a
chr6_+_58569808 0.32 ENSDART00000154393
helicase with zinc finger 2, transcriptional coactivator
chr24_-_28419444 0.32 ENSDART00000105749
negative regulator of reactive oxygen species
chr2_+_42005475 0.31 ENSDART00000056461
guanylate binding protein 2
chr23_+_43668756 0.31 ENSDART00000112598
OTU deubiquitinase 4
chr4_+_18707174 0.31 ENSDART00000142343
wingless-type MMTV integration site family, member 7Ba
chr6_+_52947186 0.31 ENSDART00000155831
ubiquitin-like modifier activating enzyme 7
chr12_-_19151708 0.31 ENSDART00000057124
thyrotrophic embryonic factor a
chr18_-_38270430 0.30 ENSDART00000139519
cell cycle associated protein 1b
chr11_+_11974708 0.30 ENSDART00000125060
zgc:64002
chr4_-_31993240 0.30 ENSDART00000167842
si:dkey-72l17.5
chr25_-_25550938 0.29 ENSDART00000150412
ENSDART00000103622
interferon regulatory factor 7
chr12_-_290782 0.28 ENSDART00000152527
ENSDART00000105694
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr9_-_43001898 0.28 ENSDART00000138515
titin, tandem duplicate 2
chr22_-_6941098 0.28 ENSDART00000105864
zgc:171500
chr16_+_13855039 0.28 ENSDART00000113764
ENSDART00000143983
zgc:174888
chr10_+_7719796 0.28 ENSDART00000191795
gamma-glutamyl carboxylase
chr22_+_34616151 0.28 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
chr9_+_51147764 0.28 ENSDART00000188480
interferon induced with helicase C domain 1
chr5_+_8919698 0.27 ENSDART00000046440
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr3_+_36127287 0.27 ENSDART00000058605
ENSDART00000182500
serine carboxypeptidase 1
chr6_+_29217392 0.27 ENSDART00000006386
ATPase Na+/K+ transporting subunit beta 1a
chr3_-_1938588 0.27 ENSDART00000013001
ENSDART00000186405
zgc:152753
chr3_-_49015203 0.27 ENSDART00000186138

chr10_+_35152928 0.27 ENSDART00000063418
NOP2/Sun domain family, member 5
chr25_-_27665978 0.27 ENSDART00000123590
si:ch211-91p5.3
chr15_-_24588649 0.26 ENSDART00000060469
gem (nuclear organelle) associated protein 4
chr15_-_47929455 0.26 ENSDART00000064462
proteasome subunit alpha 6, like
chr17_+_45395846 0.26 ENSDART00000058793
neudesin neurotrophic factor
chr22_-_8536482 0.26 ENSDART00000148134
si:ch73-27e22.2
chr25_+_35942867 0.26 ENSDART00000066985
hydroxysteroid (17-beta) dehydrogenase 2
chr17_+_35362851 0.26 ENSDART00000137659
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr5_+_38684651 0.25 ENSDART00000137852
si:dkey-58f10.10
chr1_-_49530615 0.25 ENSDART00000113315
si:ch211-281g13.5
chr4_-_71177920 0.25 ENSDART00000158287
si:dkey-193i10.1
chr22_-_8692305 0.25 ENSDART00000181602

chr11_+_1584747 0.25 ENSDART00000154583
si:dkey-40c23.2
chr22_-_10580194 0.24 ENSDART00000105848
si:dkey-42i9.7
chr23_-_37536127 0.24 ENSDART00000078253
torsin family 1 like 1
chr14_-_16810401 0.24 ENSDART00000158396
ENSDART00000170758
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr4_-_51693601 0.23 ENSDART00000189025
ENSDART00000185516
ENSDART00000189576
si:dkeyp-90h9.1
chr21_-_22673758 0.23 ENSDART00000164910
grass carp reovirus (GCRV)-induced gene 2i
chr4_+_70791887 0.23 ENSDART00000164234
si:ch211-127b6.2
chr15_-_43873005 0.23 ENSDART00000190326
NADPH oxidase 4
chr19_-_325584 0.23 ENSDART00000134266
glycerol-3-phosphate dehydrogenase 1c
chr4_+_34417403 0.23 ENSDART00000186032
ENSDART00000167909
si:ch211-246b8.2
chr5_-_57723929 0.23 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr2_-_43135700 0.23 ENSDART00000098284
finTRIM family, member 14
chr22_+_9060699 0.23 ENSDART00000133993

chr21_-_30994577 0.22 ENSDART00000065503
post-GPI attachment to proteins 2
chr4_+_68476490 0.22 ENSDART00000168543
si:dkey-237g15.2
chr24_+_10310577 0.22 ENSDART00000141718
OTU deubiquitinase with linear linkage specificity a
chr4_+_70782916 0.22 ENSDART00000187960
si:dkey-16p6.1
chr3_-_4455951 0.22 ENSDART00000193908
ENSDART00000074077
tripartite motif containing 35-3
chr9_+_42269059 0.22 ENSDART00000113435
si:dkey-10c21.1
chr21_+_5192016 0.21 ENSDART00000139288
si:dkey-121h17.7
chr4_-_58945951 0.21 ENSDART00000159145
si:dkey-28i19.4
chr8_+_47188154 0.21 ENSDART00000137319
si:dkeyp-100a1.6
chr4_-_31699842 0.21 ENSDART00000166400
si:dkey-265e15.5
chr5_-_64103863 0.21 ENSDART00000135014
ENSDART00000083684
pregnancy-associated plasma protein A, pappalysin 1b
chr9_-_35633827 0.20 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr17_-_23631400 0.20 ENSDART00000079563
Fas cell surface death receptor
chr16_+_26439939 0.20 ENSDART00000143073
tripartite motif containing 35-28
chr4_-_40008579 0.20 ENSDART00000167236
si:ch211-215p11.1
chr23_-_37575030 0.20 ENSDART00000031875
torsin family 1 like 3
chr15_-_16384184 0.20 ENSDART00000154504
family with sequence similarity 222, member Bb
chr2_+_20539402 0.20 ENSDART00000129585
si:ch73-14h1.2
chr5_+_32845759 0.20 ENSDART00000136552
si:ch211-208h16.4
chr21_+_20901505 0.20 ENSDART00000132741
complement component 7b
chr5_+_38743644 0.20 ENSDART00000137658
si:dkey-58f10.6
chr4_-_46948863 0.19 ENSDART00000168835
si:dkey-16p6.1
chr6_-_52234796 0.19 ENSDART00000001803
translocase of outer mitochondrial membrane 34
chr5_-_24869213 0.19 ENSDART00000112287
ENSDART00000144635
growth arrest-specific 2 like 1
chr12_-_44018667 0.19 ENSDART00000170692
si:dkey-201i2.4
chr18_+_34667486 0.19 ENSDART00000163583

chr4_+_34417798 0.19 ENSDART00000157757
si:ch211-246b8.2
chr10_-_42147318 0.19 ENSDART00000134890
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr4_-_75616197 0.19 ENSDART00000157778
si:dkey-71l4.3
chr22_-_36750589 0.19 ENSDART00000010824
aminoacylase 1
chr4_-_75511162 0.19 ENSDART00000157651
si:dkey-71l4.5
chr19_+_4066449 0.19 ENSDART00000162461
bloodthirsty-related gene family, member 26
chr6_-_51811095 0.18 ENSDART00000161048
proteasome inhibitor subunit 1
chr4_-_76079075 0.18 ENSDART00000158469
si:ch211-232d10.3
chr4_+_58240778 0.18 ENSDART00000181184
ENSDART00000192348
ENSDART00000189444
ENSDART00000164424
si:dkey-16p6.1
chr23_-_37835794 0.18 ENSDART00000137358
CD40 molecule, TNF receptor superfamily member 5
chr23_+_642395 0.18 ENSDART00000186995
interferon regulatory factor 10
chr4_-_45043716 0.18 ENSDART00000181920
si:ch211-227e10.6
chr2_+_20868286 0.17 ENSDART00000062591
odr-4 GPCR localization factor homolog
chr4_-_76206413 0.17 ENSDART00000170738
si:ch211-106j21.5
chr4_+_35130622 0.17 ENSDART00000165372
si:dkey-279j5.1
chr13_-_25548733 0.17 ENSDART00000168099
ENSDART00000135788
ENSDART00000077655
minichromosome maintenance complex binding protein
chr4_+_70911498 0.17 ENSDART00000157674
si:dkey-16p6.1
chr15_-_37867995 0.16 ENSDART00000192698
si:dkey-238d18.4
chr3_-_7997887 0.16 ENSDART00000172256
si:ch211-175l6.2
chr4_-_45028479 0.16 ENSDART00000143150
ENSDART00000076870
si:dkey-51d8.1
chr4_+_5842433 0.16 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr6_-_19271210 0.16 ENSDART00000163628
ENSDART00000159124
zgc:174863
chr18_+_13248956 0.16 ENSDART00000080709
phospholipase C, gamma 2
chr4_-_42244412 0.16 ENSDART00000172686
si:ch211-129p6.2
chr12_+_38556462 0.16 ENSDART00000021069
ENSDART00000145377
ribosomal protein L38
chr6_+_32834760 0.16 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr7_+_17908235 0.15 ENSDART00000077113
metastasis associated 1 family, member 2
chr3_-_22366032 0.15 ENSDART00000029849
interferon phi 1
chr4_+_35198656 0.15 ENSDART00000187990
si:dkey-269p2.1
chr15_+_13984879 0.15 ENSDART00000159438
zgc:162730
chr10_+_2899108 0.15 ENSDART00000147031
endoplasmic reticulum aminopeptidase 1a
chr1_-_25177086 0.15 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr1_-_30510839 0.15 ENSDART00000168189
ENSDART00000174868
insulin-like growth factor 2 mRNA binding protein 2b
chr1_+_58332000 0.15 ENSDART00000145234
gamma-glutamyltransferase 1 like 2.1
chr3_+_40164129 0.15 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr2_-_32688905 0.15 ENSDART00000041146
nuclear receptor binding protein 2a
chr15_-_17169935 0.15 ENSDART00000110111
cullin 5a
chr16_+_25806400 0.15 ENSDART00000154652
immunity-related GTPase family, q1
chr5_+_27421639 0.15 ENSDART00000146285
cytochrome b561 family, member A3a
chr5_-_39171302 0.14 ENSDART00000020808
progestin and adipoQ receptor family member IIIa
chr4_-_56673431 0.14 ENSDART00000161464
ENSDART00000191926
si:ch211-227p7.5
chr4_+_40329524 0.14 ENSDART00000165722
zinc finger protein 993
chr23_+_642001 0.14 ENSDART00000030643
ENSDART00000124850
interferon regulatory factor 10
chr4_-_55227527 0.14 ENSDART00000184323
ENSDART00000148091
si:dkey-61p9.9
chr2_+_42708674 0.14 ENSDART00000141989
ENSDART00000005767
finTRIM family, member 11
chr22_+_2512154 0.14 ENSDART00000097363
zgc:173726
chr4_+_53115165 0.14 ENSDART00000157470
si:dkey-8o9.2
chr4_-_26095755 0.14 ENSDART00000100611
ENSDART00000191266
si:ch211-244b2.3
chr13_-_45155792 0.14 ENSDART00000163556
runt-related transcription factor 3
chr19_-_27448606 0.14 ENSDART00000079251
valyl-tRNA synthetase 2, mitochondrial (putative)
chr10_-_36808348 0.14 ENSDART00000099320
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr14_-_45967712 0.14 ENSDART00000043751
ENSDART00000141357
MACRO domain containing 1
chr10_+_26646104 0.14 ENSDART00000187685
adhesion G protein-coupled receptor G4b
chr4_-_76129431 0.14 ENSDART00000162809
si:ch211-106j21.2
chr2_-_24554416 0.13 ENSDART00000052061
calponin 2
chr4_-_76239517 0.13 ENSDART00000172599
si:ch211-106j21.6
chr3_-_22366562 0.13 ENSDART00000129447
interferon phi 1
chr4_-_51692811 0.13 ENSDART00000159625
si:dkeyp-90h9.1
chr9_-_40935934 0.13 ENSDART00000155604
Small membrane A-kinase anchor protein
chr4_-_32466676 0.13 ENSDART00000193347
ENSDART00000169396
ENSDART00000145784
si:dkey-16p6.1
chr23_+_14269311 0.13 ENSDART00000170414

chr22_+_9009496 0.13 ENSDART00000132667
si:ch211-213a13.2
chr15_-_42760110 0.13 ENSDART00000152490
si:ch211-181d7.3
chr4_-_40008099 0.13 ENSDART00000165574
ENSDART00000171888
si:ch211-215p11.1
chr4_+_43522945 0.12 ENSDART00000183921
ENSDART00000181832
si:dkeyp-53e4.4
chr3_-_49925313 0.12 ENSDART00000164361
glucagon receptor a

Network of associatons between targets according to the STRING database.

First level regulatory network of irf10+irf8+irf9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.5 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 0.3 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.1 0.5 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.4 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 2.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.3 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 1.2 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.3 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0031179 peptide modification(GO:0031179)
0.1 0.4 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.2 GO:0042832 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 1.1 GO:0006825 copper ion transport(GO:0006825)
0.1 0.2 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.0 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.3 GO:0098773 skin epidermis development(GO:0098773)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.2 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 2.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 3.7 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 2.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
0.1 0.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 2.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA