Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for hoxc6a+hoxc6b

Z-value: 0.93

Motif logo

Transcription factors associated with hoxc6a+hoxc6b

Gene Symbol Gene ID Gene Info
ENSDARG00000070343 homeobox C6a
ENSDARG00000101954 homeobox C6b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc6bdr11_v1_chr11_+_2198831_21988310.915.2e-08Click!
hoxc6adr11_v1_chr23_+_36115541_361155410.068.2e-01Click!

Activity profile of hoxc6a+hoxc6b motif

Sorted Z-values of hoxc6a+hoxc6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_16422654 4.31 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr16_+_54209504 3.27 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr3_-_19368435 3.03 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr17_+_30369396 2.92 ENSDART00000076611
growth regulation by estrogen in breast cancer 1
chr16_+_29509133 2.66 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr25_-_21031007 2.56 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr2_-_31833347 2.33 ENSDART00000109460
nucleolar protein 7
chr22_-_16154771 2.27 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr2_+_15048410 2.20 ENSDART00000058484
calponin 3, acidic b
chr21_-_26490186 2.12 ENSDART00000009889
zgc:110540
chr25_+_22320738 1.99 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr7_+_26534131 1.92 ENSDART00000173980
si:dkey-62k3.5
chr1_-_22851481 1.92 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr23_-_18913032 1.89 ENSDART00000136678
si:ch211-209j10.6
chr1_+_19303241 1.86 ENSDART00000129970
si:dkeyp-118a3.2
chr20_+_54299419 1.78 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr24_+_21514283 1.74 ENSDART00000007066
cyclin-dependent kinase 8
chr20_+_54309148 1.73 ENSDART00000099360
zona pellucida glycoprotein 2, tandem duplicate 1
chr2_-_10877765 1.72 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr1_+_22851261 1.70 ENSDART00000193925
general transcription factor IIE, polypeptide 2, beta
chr24_-_38657683 1.70 ENSDART00000154843
si:ch1073-164k15.3
chr16_-_21140097 1.69 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
chr7_-_8712148 1.68 ENSDART00000065488
testis expressed 261
chr21_+_43172506 1.65 ENSDART00000121725
zinc finger, CCHC domain containing 10
chr23_-_16485190 1.63 ENSDART00000155038
si:dkeyp-100a5.4
chr17_-_29224908 1.61 ENSDART00000156288
si:dkey-28g23.6
chr20_+_54304800 1.58 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr16_+_28728347 1.56 ENSDART00000149240
si:dkey-24i24.3
chr20_+_11731039 1.56 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
chr4_+_57881965 1.54 ENSDART00000162234
si:dkeyp-44b5.4
chr11_-_10456553 1.53 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
epithelial cell transforming 2
chr6_+_7533601 1.51 ENSDART00000057823
proliferation-associated 2G4, a
chr16_+_4654333 1.48 ENSDART00000167665
si:ch1073-284b18.2
chr14_-_16082806 1.47 ENSDART00000165656
MAX dimerization protein 3
chr22_-_36530902 1.44 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr11_-_10456387 1.43 ENSDART00000011087
ENSDART00000081827
epithelial cell transforming 2
chr23_+_1029450 1.41 ENSDART00000189196
si:zfos-905g2.1
chr1_+_513986 1.41 ENSDART00000109083
ENSDART00000081945
thioredoxin-like 4B
chr7_-_5375214 1.39 ENSDART00000033316
VANGL planar cell polarity protein 2
chr5_+_41477954 1.38 ENSDART00000185871
protein inhibitor of activated STAT, 2
chr16_-_7793457 1.35 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr22_-_5252005 1.34 ENSDART00000132942
ENSDART00000081801
nicalin
chr1_-_42289704 1.30 ENSDART00000150124
si:ch211-71k14.1
chr24_+_34113424 1.30 ENSDART00000105572
gastrulation brain homeobox 1
chr5_+_61459422 1.25 ENSDART00000050902
polymerase (RNA) II (DNA directed) polypeptide J
chr24_+_19415124 1.24 ENSDART00000186931
sulfatase 1
chr3_+_40164129 1.23 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr11_+_34760628 1.20 ENSDART00000087216
si:dkey-202e22.2
chr13_+_43247936 1.20 ENSDART00000126850
ENSDART00000165331
SPARC related modular calcium binding 2
chr2_+_10878406 1.20 ENSDART00000091497
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr5_+_41477526 1.18 ENSDART00000153567
protein inhibitor of activated STAT, 2
chr1_-_669717 1.18 ENSDART00000160564
cysteine/tyrosine-rich 1
chr20_+_25586099 1.12 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr20_+_40457599 1.12 ENSDART00000017553
serine incorporator 1
chr13_-_12602920 1.08 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr1_+_27977297 1.08 ENSDART00000180692
ENSDART00000166819
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr6_-_43283122 1.08 ENSDART00000186022
FERM domain containing 4Ba
chr5_+_66433287 1.05 ENSDART00000170757
kinetochore associated 1
chr10_+_22527715 1.03 ENSDART00000134864
GRB10 interacting GYF protein 1b
chr8_+_26874924 1.03 ENSDART00000141794
ribosomal modification protein rimK-like family member A
chr20_+_25225112 0.97 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
monooxygenase, DBH-like 1
chr24_+_21540842 0.97 ENSDART00000091529
WAS protein family, member 3b
chr20_-_45812144 0.96 ENSDART00000147897
ENSDART00000147637
fermitin family member 1
chr10_+_11767791 0.95 ENSDART00000092047
peptidylprolyl isomerase domain and WD repeat containing 1
chr22_-_21676364 0.93 ENSDART00000183668
transducin like enhancer of split 2b
chr21_-_26028205 0.91 ENSDART00000034875
stromal cell-derived factor 2
chr14_+_4807207 0.91 ENSDART00000167145
adaptor-related protein complex 1 associated regulatory protein
chr25_-_27722614 0.90 ENSDART00000190154
zgc:153935
chr16_-_27677930 0.88 ENSDART00000145991
transforming growth factor beta regulator 4
chr23_-_36418708 0.88 ENSDART00000132273
zinc finger protein 740b
chr19_+_43359075 0.88 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
Yes-related kinase
chr6_+_35362225 0.86 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr8_+_29635968 0.85 ENSDART00000139029
ENSDART00000091409
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr16_-_42965192 0.84 ENSDART00000113714
metaxin 1a
chr22_+_508290 0.82 ENSDART00000135403
NUAK family, SNF1-like kinase, 2
chr17_+_41992054 0.82 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr25_-_37186894 0.81 ENSDART00000191647
ENSDART00000182095
tudor domain containing 12
chr9_-_30576522 0.80 ENSDART00000101085
MORC family CW-type zinc finger 3a
chr12_-_28363111 0.80 ENSDART00000016283
ENSDART00000164156
proteasome 26S subunit, non-ATPase 11b
chr6_+_4229360 0.79 ENSDART00000191347
ENSDART00000130642

chr3_+_26342768 0.79 ENSDART00000163832
si:ch211-156b7.4
chr3_+_38540411 0.75 ENSDART00000154943
si:dkey-7f16.3
chr21_+_25236297 0.75 ENSDART00000112783
transmembrane protein 45B
chr2_+_27010439 0.74 ENSDART00000030547
cadherin 7a
chr11_+_17984354 0.74 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr19_+_10592778 0.73 ENSDART00000135488
ENSDART00000151624
si:dkey-211g8.5
chr23_+_4709607 0.71 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr11_+_11974708 0.70 ENSDART00000125060
zgc:64002
chr5_+_32076109 0.70 ENSDART00000051357
ENSDART00000144510
zinc finger, matrin-type 5
chr1_-_51038885 0.69 ENSDART00000035150
spastin
chr15_-_43284021 0.69 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_+_19495905 0.69 ENSDART00000125584
ENSDART00000173774
si:ch211-212k18.8
chr3_+_28939759 0.68 ENSDART00000141904
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr8_+_50953776 0.67 ENSDART00000013870
zgc:56596
chr7_-_34448076 0.67 ENSDART00000170935
nuclear receptor subfamily 1, group H, member 3
chr22_-_24791505 0.66 ENSDART00000136837
vitellogenin 4
chr4_-_43388943 0.66 ENSDART00000150796
si:dkey-29j8.2
chr21_+_37090585 0.65 ENSDART00000182971
zinc finger protein 346
chr7_+_7696665 0.62 ENSDART00000091099
INO80 complex subunit B
chr11_+_37250839 0.62 ENSDART00000170209
interleukin 17 receptor C
chr7_-_67248829 0.61 ENSDART00000192442
zinc finger protein 143a
chr21_-_32097908 0.61 ENSDART00000147387
si:ch211-160j14.3
chr6_+_25257728 0.61 ENSDART00000162581
kynurenine aminotransferase 3
chr2_+_11923615 0.60 ENSDART00000126118
TROVE domain family, member 2
chr8_+_17775247 0.59 ENSDART00000112356
si:ch211-150o23.3
chr8_-_30204650 0.58 ENSDART00000133209
zgc:162939
chr20_-_9095105 0.58 ENSDART00000140792
OMA1 zinc metallopeptidase
chr17_+_51682429 0.57 ENSDART00000004379
nucleolar protein 10
chr9_+_41080029 0.57 ENSDART00000141179
ENSDART00000019289
zgc:136439
chr11_-_36156935 0.57 ENSDART00000124935
ENSDART00000138609
BRICK1, SCAR/WAVE actin-nucleating complex subunit
glutathione peroxidase 1a
chr1_+_47499888 0.57 ENSDART00000027624
STN1, CST complex subunit
chr9_+_23895711 0.56 ENSDART00000034686
COP9 signalosome subunit 8
chr3_+_46635527 0.56 ENSDART00000153971
si:dkey-248g21.1
chr17_+_20589553 0.55 ENSDART00000154447
si:ch73-288o11.4
chr2_-_17393216 0.54 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr4_-_43640507 0.54 ENSDART00000150700
si:dkey-29p23.2
chr15_+_857148 0.54 ENSDART00000156949
si:dkey-7i4.13
chr24_+_9693951 0.52 ENSDART00000082411
DNA topoisomerase II binding protein 1
chr24_+_28953089 0.50 ENSDART00000153761
RNA-binding region (RNP1, RRM) containing 3
chr15_+_29140126 0.50 ENSDART00000060034
zgc:113149
chr9_+_11281969 0.50 ENSDART00000110691
wingless-type MMTV integration site family, member 6b
chr2_+_20406399 0.49 ENSDART00000006817
ENSDART00000137848
palmdelphin a
chr2_+_2169337 0.48 ENSDART00000179939
HIG1 hypoxia inducible domain family, member 1A
chr13_+_9468535 0.47 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
si:dkey-265c15.6
chr3_-_31158382 0.47 ENSDART00000076764
ENSDART00000076796
SMG1 phosphatidylinositol 3-kinase-related kinase
chr21_-_1640547 0.45 ENSDART00000151041
zgc:152948
chr22_-_9183944 0.45 ENSDART00000188599
si:ch211-213a13.5
chr11_+_17984167 0.44 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr6_+_49551614 0.43 ENSDART00000022581
RAB22A, member RAS oncogene family
chr9_-_32177117 0.42 ENSDART00000078568
splicing factor 3b, subunit 1
chr2_-_17392799 0.42 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr6_+_12527725 0.40 ENSDART00000149328
serine/threonine kinase 24b (STE20 homolog, yeast)
chr10_-_43771447 0.39 ENSDART00000052307
arrestin domain containing 3b
chr10_+_29850330 0.39 ENSDART00000168898
heat shock protein 8
chr7_+_4474880 0.39 ENSDART00000143528
si:dkey-83f18.14
chr11_+_11267493 0.39 ENSDART00000148425
protein tyrosine phosphatase type IVA, member 1
chr11_-_40728380 0.39 ENSDART00000023745
coiled-coil domain containing 114
chr7_+_4657987 0.39 ENSDART00000144321
ENSDART00000142344
si:dkey-83f18.2
chr10_+_34047352 0.39 ENSDART00000169333
si:dkey-10b15.8
chr8_-_53044300 0.38 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr6_-_16717878 0.37 ENSDART00000153552
nodal modulator
chr22_-_20166660 0.37 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr2_-_59327299 0.36 ENSDART00000133734
finTRIM family, member 36
chr3_+_52545014 0.35 ENSDART00000018908
solute carrier family 27 (fatty acid transporter), member 1a
chr12_+_23912074 0.35 ENSDART00000152864
supervillin a
chr4_-_11064073 0.35 ENSDART00000150760
si:dkey-21h14.8
chr7_+_4694924 0.33 ENSDART00000144873
si:ch211-225k7.3
chr7_+_66884570 0.33 ENSDART00000082664
SET binding factor 2
chr4_+_19700308 0.33 ENSDART00000027919
paired box 4
chr13_+_35528607 0.32 ENSDART00000075414
ENSDART00000112947
WD repeat domain 27
chr4_-_5108844 0.32 ENSDART00000132666
ENSDART00000136096
transmembrane protein 209
chr17_-_25831569 0.31 ENSDART00000148743
hedgehog acyltransferase
chr8_+_31717175 0.31 ENSDART00000013434
3-oxoacid CoA transferase 1a
chr22_+_2751887 0.30 ENSDART00000133652
si:dkey-20i20.11
chr14_-_34771371 0.30 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr4_+_59845617 0.30 ENSDART00000167626
ENSDART00000123157
si:dkey-196n19.2
chr13_+_33268657 0.29 ENSDART00000002095
transmembrane protein 39B
chr24_+_16985181 0.27 ENSDART00000135580
eukaryotic translation initiation factor 2, subunit 3 gamma
chr18_+_20481982 0.26 ENSDART00000128139
kelch repeat and BTB (POZ) domain containing 4
chr15_-_17619306 0.26 ENSDART00000184011
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr19_+_46158078 0.26 ENSDART00000183933
ENSDART00000164055
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr16_+_13818743 0.25 ENSDART00000090191
folliculin
chr5_+_33498253 0.25 ENSDART00000140993
membrane-spanning 4-domains, subfamily A, member 17c.2
chr23_-_19140781 0.25 ENSDART00000143580
si:ch73-381f5.2
chr9_+_24065855 0.24 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr2_+_31833997 0.23 ENSDART00000066788
ependymin related 1
chr19_+_1688727 0.23 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr7_+_4694762 0.23 ENSDART00000132862
si:ch211-225k7.3
chr2_+_19522082 0.22 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr2_-_37140423 0.22 ENSDART00000144220
tetraspanin 37
chr13_-_9467944 0.22 ENSDART00000136582
Pim proto-oncogene, serine/threonine kinase, related 152
chr15_-_2754056 0.21 ENSDART00000129380
protein phosphatase 5, catalytic subunit
chr22_-_28226948 0.21 ENSDART00000147686
si:dkey-222p3.1
chr4_-_67980261 0.20 ENSDART00000182305
si:ch211-223k15.1
chr7_+_19495379 0.20 ENSDART00000180514
si:ch211-212k18.8
chr13_+_35339182 0.20 ENSDART00000019323
jagged 1b
chr7_+_66884291 0.19 ENSDART00000187499
SET binding factor 2
chr4_+_2482046 0.18 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr10_-_34046757 0.18 ENSDART00000099648
Pim proto-oncogene, serine/threonine kinase, related 149
chr23_-_18707418 0.17 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr13_+_15656042 0.17 ENSDART00000134240
MAP/microtubule affinity-regulating kinase 3a
chr24_-_40860603 0.17 ENSDART00000188032

chr5_-_51198430 0.16 ENSDART00000132503
ENSDART00000097473
ENSDART00000165870
small nuclear RNA activating complex, polypeptide 4
chr1_+_58242498 0.15 ENSDART00000149091
gamma-glutamyltransferase 1 like 2.2
chr19_+_7847920 0.14 ENSDART00000132454
si:dkeyp-85e10.1
chr2_+_37140448 0.14 ENSDART00000045016
ENSDART00000142940
peroxisomal biogenesis factor 19
chr2_+_19578079 0.13 ENSDART00000144413
Pim proto-oncogene, serine/threonine kinase, related 50
chr7_+_4702269 0.12 ENSDART00000139880
si:ch211-225k7.4
chr7_-_46777876 0.12 ENSDART00000193954
teashirt zinc finger homeobox 3b
chr20_+_22799641 0.12 ENSDART00000131132
sec1 family domain containing 2
chr17_+_12285285 0.11 ENSDART00000154336
Pim proto-oncogene, serine/threonine kinase, related 174
chr10_+_31248036 0.11 ENSDART00000193574
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr20_+_46202188 0.11 ENSDART00000100523
trace amine associated receptor 13c
chr7_+_59020972 0.11 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr14_-_7137808 0.11 ENSDART00000054803
tRNA phosphotransferase 1
chr5_+_56023186 0.11 ENSDART00000156230
frizzled class receptor 9a
chr12_-_35944654 0.10 ENSDART00000162579
ENSDART00000164199
dynein, axonemal, intermediate chain 2a
chr5_-_66702479 0.09 ENSDART00000129197
meningioma 1b
chr1_+_49668423 0.09 ENSDART00000150880
testis specific, 10
chr3_+_23029484 0.09 ENSDART00000187900
N-acetylglutamate synthase

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc6a+hoxc6b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.6 GO:0000012 single strand break repair(GO:0000012)
0.4 2.0 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.3 1.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 1.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.3 1.0 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.3 1.4 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 3.0 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.7 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 0.9 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.2 0.7 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.2 1.3 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.2 1.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 0.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 1.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 0.9 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 2.9 GO:0021983 pituitary gland development(GO:0021983)
0.1 1.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.6 GO:0010269 response to selenium ion(GO:0010269)
0.1 2.6 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.5 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 1.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 0.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.7 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.4 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.7 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.9 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.2 GO:0042476 odontogenesis(GO:0042476)
0.0 1.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0045761 cAMP biosynthetic process(GO:0006171) regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 1.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.7 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.6 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 1.1 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.8 GO:0032355 response to estradiol(GO:0032355)
0.0 0.2 GO:0060325 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 4.0 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 2.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.6 GO:1990879 CST complex(GO:1990879)
0.1 0.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.0 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 1.2 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.7 2.0 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 1.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 3.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 1.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.3 1.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.3 2.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 2.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 2.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.0 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 1.4 GO:0035198 miRNA binding(GO:0035198)
0.1 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 1.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 3.3 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.2 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.6 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2 2.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 2.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 4.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis