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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxc4a

Z-value: 0.36

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Transcription factors associated with hoxc4a

Gene Symbol Gene ID Gene Info
ENSDARG00000070338 homeobox C4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc4adr11_v1_chr23_+_36130883_361308830.455.2e-02Click!

Activity profile of hoxc4a motif

Sorted Z-values of hoxc4a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_21453614 0.66 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr17_-_16422654 0.66 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr14_+_16287968 0.63 ENSDART00000106593
pre-mRNA processing factor 19
chr16_+_54209504 0.57 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr24_+_21514283 0.53 ENSDART00000007066
cyclin-dependent kinase 8
chr16_-_42894628 0.53 ENSDART00000045600
hemochromatosis type 2
chr12_-_35830625 0.53 ENSDART00000180028

chr9_-_1986014 0.53 ENSDART00000142842
homeobox D12a
chr1_+_23261857 0.52 ENSDART00000192774

chr1_-_31534089 0.51 ENSDART00000007770
ladybird homeobox 1b
chr2_+_105748 0.49 ENSDART00000169601

chr9_-_27398369 0.48 ENSDART00000186499
testis expressed 30
chr5_+_41477954 0.47 ENSDART00000185871
protein inhibitor of activated STAT, 2
chr4_+_16715267 0.46 ENSDART00000143849
plakophilin 2
chr5_+_41477526 0.46 ENSDART00000153567
protein inhibitor of activated STAT, 2
chr25_-_21031007 0.41 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr11_+_24815667 0.41 ENSDART00000141730
RAB interacting factor
chr7_+_38811800 0.41 ENSDART00000052322
zgc:110699
chr4_+_57881965 0.41 ENSDART00000162234
si:dkeyp-44b5.4
chr3_+_40164129 0.40 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr6_-_33878665 0.40 ENSDART00000129916
transmembrane protein 69
chr12_-_4243268 0.40 ENSDART00000131275
zgc:92313
chr20_+_40457599 0.39 ENSDART00000017553
serine incorporator 1
chr1_-_51038885 0.38 ENSDART00000035150
spastin
chr19_+_10855158 0.37 ENSDART00000172219
ENSDART00000170826
apolipoprotein Ea
chr20_+_29209615 0.36 ENSDART00000062350
katanin p80 subunit B-like 1
chr14_-_26425416 0.36 ENSDART00000088690
lectin, mannose-binding 2
chr19_+_3213914 0.36 ENSDART00000193144
zgc:86598
chr6_+_36821621 0.36 ENSDART00000104157
transmembrane protein 45a
chr2_+_38373272 0.35 ENSDART00000113111
proteasome subunit beta 5
chr22_+_508290 0.35 ENSDART00000135403
NUAK family, SNF1-like kinase, 2
chr2_-_22631498 0.34 ENSDART00000146425
serine/threonine kinase 25b
chr2_+_11685742 0.34 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr18_+_41527877 0.33 ENSDART00000146972
selenoprotein T, 1b
chr14_-_15956921 0.33 ENSDART00000190500
fms-related tyrosine kinase 4
chr23_-_16485190 0.33 ENSDART00000155038
si:dkeyp-100a5.4
chr24_+_28953089 0.33 ENSDART00000153761
RNA-binding region (RNP1, RRM) containing 3
chr12_-_31794908 0.33 ENSDART00000105583
ENSDART00000153449
N-acetyltransferase 9 (GCN5-related, putative)
chr23_+_20640484 0.32 ENSDART00000054691
ubiquitin-like modifier activating enzyme 1
chr1_+_513986 0.32 ENSDART00000109083
ENSDART00000081945
thioredoxin-like 4B
chr3_+_13848226 0.31 ENSDART00000184342
interleukin enhancer binding factor 3b
chr15_-_34668485 0.31 ENSDART00000186605
BCL2 associated athanogene 6
chr8_+_29742237 0.31 ENSDART00000133955
ENSDART00000020621
mitogen-activated protein kinase 4
chr7_-_8712148 0.30 ENSDART00000065488
testis expressed 261
chr10_-_31015535 0.30 ENSDART00000146116
pannexin 3
chr24_-_25691020 0.30 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr6_-_8392104 0.30 ENSDART00000081561
ENSDART00000181178
interleukin enhancer binding factor 3a
chr24_-_38657683 0.30 ENSDART00000154843
si:ch1073-164k15.3
chr22_-_36530902 0.29 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr9_+_23895711 0.29 ENSDART00000034686
COP9 signalosome subunit 8
chr6_-_40029423 0.29 ENSDART00000103230
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr3_-_34136778 0.28 ENSDART00000131951
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr15_-_43284021 0.28 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr20_+_48116476 0.27 ENSDART00000043938
translocation associated membrane protein 2
chr1_-_669717 0.27 ENSDART00000160564
cysteine/tyrosine-rich 1
chr20_+_29209767 0.27 ENSDART00000141252
katanin p80 subunit B-like 1
chr25_+_22320738 0.25 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr9_+_37152564 0.25 ENSDART00000189497
GLI family zinc finger 2a
chr3_-_26806032 0.25 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr2_+_50608099 0.25 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr2_+_20793982 0.25 ENSDART00000014785
proteoglycan 4a
chr13_-_35808904 0.24 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr11_+_34760628 0.24 ENSDART00000087216
si:dkey-202e22.2
chr9_-_14504834 0.24 ENSDART00000056103
neuropilin 2b
chr20_+_54304800 0.24 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr20_+_98179 0.23 ENSDART00000022725
si:ch1073-155h21.1
chr8_+_30664077 0.22 ENSDART00000138750
adenosine A2a receptor a
chr7_+_21272833 0.22 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr20_+_29209926 0.22 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr24_+_24461558 0.22 ENSDART00000182424
basic helix-loop-helix family, member e22
chr10_+_16225117 0.22 ENSDART00000169885
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr6_-_55399214 0.22 ENSDART00000168367
cathepsin A
chr22_-_16042243 0.22 ENSDART00000062633
sphingosine-1-phosphate receptor 1
chr2_+_36701322 0.22 ENSDART00000002510
golgi integral membrane protein 4b
chr17_+_22577472 0.21 ENSDART00000045099
Yip1 domain family, member 4
chr23_-_17657348 0.21 ENSDART00000054736
basic helix-loop-helix family, member e23
chr12_+_17620067 0.21 ENSDART00000073599
radial spoke head 10 homolog B
chr21_+_25236297 0.21 ENSDART00000112783
transmembrane protein 45B
chr14_+_22591624 0.20 ENSDART00000108987
GDNF family receptor alpha 4b
chr20_-_37813863 0.20 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr18_-_17485419 0.20 ENSDART00000018764
forkhead box L1
chr6_-_35052145 0.20 ENSDART00000073970
ENSDART00000185790
UDP-N-acetylglucosamine pyrophosphorylase 1
chr19_-_8877469 0.20 ENSDART00000193951
cugbp, Elav-like family member 3a
chr13_+_48358467 0.20 ENSDART00000171080
ENSDART00000162531
mutS homolog 6 (E. coli)
chr23_+_12134839 0.20 ENSDART00000128551
ENSDART00000141204
tubulin tyrosine ligase-like family, member 9
chr3_+_26288981 0.19 ENSDART00000163500
ras homolog family member T1a
chr18_+_14619544 0.19 ENSDART00000010821
UTP4, small subunit processome component
chr3_-_40658820 0.19 ENSDART00000191948
ring finger protein 216
chr11_+_24800156 0.18 ENSDART00000131976
adiponectin receptor 1a
chr6_+_25257728 0.18 ENSDART00000162581
kynurenine aminotransferase 3
chr24_+_24461341 0.18 ENSDART00000147658
basic helix-loop-helix family, member e22
chr1_-_45616470 0.18 ENSDART00000150165
activating transcription factor 7 interacting protein
chr24_+_21540842 0.18 ENSDART00000091529
WAS protein family, member 3b
chr22_-_10156581 0.18 ENSDART00000168304
RanBP-type and C3HC4-type zinc finger containing 1
chr3_+_36284986 0.18 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr10_+_21650828 0.17 ENSDART00000160754
protocadherin 1 gamma 1
chr19_+_2631565 0.17 ENSDART00000171487
family with sequence similarity 126, member A
chr17_+_41992054 0.17 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr4_+_69191065 0.17 ENSDART00000170595
zinc finger protein 1075
chr11_+_44617021 0.17 ENSDART00000158887
RNA binding motif protein 34
chr7_+_4474880 0.17 ENSDART00000143528
si:dkey-83f18.14
chr19_+_43359075 0.17 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
Yes-related kinase
chr5_-_38451082 0.17 ENSDART00000136428
cholinergic receptor, nicotinic, epsilon
chr18_+_7456597 0.16 ENSDART00000142270
telomere repeat binding bouquet formation protein 1
chr23_-_19225709 0.16 ENSDART00000080099
O-acyl-ADP-ribose deacylase 1
chr5_+_13394543 0.16 ENSDART00000051669
ENSDART00000135921
tectonic family member 2
chr22_+_737211 0.16 ENSDART00000017305
zinc finger protein 76
chr13_-_12602920 0.16 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr25_-_13490744 0.16 ENSDART00000056721
lactate dehydrogenase D
chr18_+_17827149 0.15 ENSDART00000190237
ENSDART00000189345
si:ch211-216l23.1
chr2_-_7845110 0.15 ENSDART00000091987
si:ch211-38m6.7
chr23_-_33679579 0.15 ENSDART00000188674
transcription factor CP2
chr3_-_29941357 0.15 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
granulin a
chr10_-_14556978 0.15 ENSDART00000126643
zgc:153395
chr4_+_77943184 0.14 ENSDART00000159094
protein kinase C and casein kinase substrate in neurons 2
chr1_+_6172786 0.14 ENSDART00000126468
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr2_-_30668580 0.14 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr9_+_11281969 0.14 ENSDART00000110691
wingless-type MMTV integration site family, member 6b
chr22_-_19552796 0.14 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr23_+_4709607 0.14 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr21_+_27513859 0.14 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr3_+_23029484 0.14 ENSDART00000187900
N-acetylglutamate synthase
chr12_-_19119176 0.14 ENSDART00000149180
aconitase 2, mitochondrial
chr4_+_9669717 0.13 ENSDART00000004604
si:dkey-153k10.9
chr1_+_49668423 0.13 ENSDART00000150880
testis specific, 10
chr6_-_11768198 0.13 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr6_-_43283122 0.13 ENSDART00000186022
FERM domain containing 4Ba
chr5_+_33498253 0.13 ENSDART00000140993
membrane-spanning 4-domains, subfamily A, member 17c.2
chr21_+_25802190 0.12 ENSDART00000128987
neurofibromin 2b (merlin)
chr16_-_42965192 0.12 ENSDART00000113714
metaxin 1a
chr2_+_42318012 0.12 ENSDART00000138137
finTRIM family, member 8
chr9_-_30576522 0.12 ENSDART00000101085
MORC family CW-type zinc finger 3a
chr2_+_10878406 0.12 ENSDART00000091497
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr20_-_9095105 0.12 ENSDART00000140792
OMA1 zinc metallopeptidase
chr4_+_36150332 0.11 ENSDART00000161697
zinc finger protein 1116
chr6_-_51771634 0.11 ENSDART00000073847
bladder cancer associated protein
chr16_+_23303859 0.11 ENSDART00000006093
solute carrier family 50 (sugar efflux transporter), member 1
chr6_-_50730749 0.11 ENSDART00000157153
ENSDART00000110441
phosphatidylinositol glycan anchor biosynthesis, class U
chr4_-_9891874 0.11 ENSDART00000067193
adrenomedullin 2a
chr10_+_26747755 0.11 ENSDART00000100329
coagulation factor IXb
chr5_+_11840905 0.10 ENSDART00000030444
tescalcin a
chr16_+_23796612 0.10 ENSDART00000131698
RAB13, member RAS oncogene family
chr8_-_45760087 0.10 ENSDART00000025620
peptidylprolyl isomerase Aa (cyclophilin A)
chr13_-_29420885 0.10 ENSDART00000024225
choline O-acetyltransferase a
chr8_-_53044300 0.10 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr2_-_17393216 0.10 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr9_-_32177117 0.10 ENSDART00000078568
splicing factor 3b, subunit 1
chr22_+_5532003 0.10 ENSDART00000106174
si:ch73-256j6.2
chr14_+_1170968 0.09 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr6_+_15373153 0.09 ENSDART00000155865
teleost multiple tissue opsin 2a
chr17_-_15229787 0.09 ENSDART00000039165
serine/threonine/tyrosine interacting protein
chr23_+_28809002 0.09 ENSDART00000134121
ENSDART00000183661
peroxisomal biogenesis factor 14
chr4_+_33017081 0.09 ENSDART00000151897
si:dkey-26h11.1
chr13_-_9450210 0.08 ENSDART00000133768
Pim proto-oncogene, serine/threonine kinase, related 152
chr22_+_26853254 0.08 ENSDART00000182487
transmembrane protein 186
chr6_-_35052388 0.08 ENSDART00000181000
ENSDART00000170116
UDP-N-acetylglucosamine pyrophosphorylase 1
chr1_+_21731382 0.08 ENSDART00000054395
paired box 5
chr2_+_37140448 0.08 ENSDART00000045016
ENSDART00000142940
peroxisomal biogenesis factor 19
chr18_+_3037998 0.08 ENSDART00000185844
ENSDART00000162657
ribosomal protein S3
chr18_+_7456888 0.08 ENSDART00000081468
telomere repeat binding bouquet formation protein 1
chr16_+_24733741 0.08 ENSDART00000155217
si:dkey-79d12.4
chr9_+_30211038 0.07 ENSDART00000190847
SUMO1/sentrin specific peptidase 7a
chr10_+_29850330 0.07 ENSDART00000168898
heat shock protein 8
chr2_-_37140423 0.07 ENSDART00000144220
tetraspanin 37
chr3_+_27606505 0.07 ENSDART00000150953
ubiquitin specific peptidase 7 (herpes virus-associated)
chr1_+_51039558 0.06 ENSDART00000024743
dpy-30 histone methyltransferase complex regulatory subunit
chr1_+_16625678 0.06 ENSDART00000164899
pericentriolar material 1
chr24_+_9693951 0.06 ENSDART00000082411
DNA topoisomerase II binding protein 1
chr15_+_32798333 0.06 ENSDART00000162370
ENSDART00000166525
spartin b
chr4_-_13548806 0.06 ENSDART00000067155
interleukin 22
chr17_-_25831569 0.06 ENSDART00000148743
hedgehog acyltransferase
chr1_+_418869 0.06 ENSDART00000152173
tripeptidyl peptidase 2
chr19_+_25154066 0.06 ENSDART00000163220
si:ch211-239d6.2
chr23_+_20669149 0.05 ENSDART00000138936
Rho guanine nucleotide exchange factor (GEF) 3, like
chr9_-_38398789 0.05 ENSDART00000188384
zinc finger protein 142
chr1_+_11882186 0.05 ENSDART00000193419
sorting nexin 8b
chr25_+_13321307 0.05 ENSDART00000161284
si:ch211-194m7.5
chr19_-_1929310 0.05 ENSDART00000144113
si:ch211-149a19.3
chr1_+_57787642 0.05 ENSDART00000127091
si:dkey-1c7.2
chr10_+_44956660 0.05 ENSDART00000169225
ENSDART00000189298
interleukin 1, beta
chr2_-_16216568 0.05 ENSDART00000173758
Rho guanine nucleotide exchange factor (GEF) 4
chr16_+_23431189 0.05 ENSDART00000004679
ictacalcin
chr12_-_47648538 0.04 ENSDART00000108477
fumarate hydratase
chr5_+_34623107 0.04 ENSDART00000184126
ectodermal-neural cortex 1
chr17_-_10122204 0.04 ENSDART00000160751

chr25_+_29474982 0.03 ENSDART00000130410
interleukin 17 receptor E-like
chr10_-_29236860 0.03 ENSDART00000111620
coiled-coil domain containing 83
chr7_-_8738827 0.03 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
chr25_-_13320986 0.03 ENSDART00000169238
si:ch211-194m7.8
chr2_+_2223837 0.02 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr11_-_2838699 0.02 ENSDART00000066189
LHFPL tetraspan subfamily member 5a
chr22_+_12770877 0.02 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr8_-_12867128 0.02 ENSDART00000142201
solute carrier family 2 (facilitated glucose transporter), member 6
chr19_+_11855330 0.01 ENSDART00000145380
aarF domain containing kinase 5
chr1_-_50438247 0.01 ENSDART00000114098
dickkopf WNT signaling pathway inhibitor 2
chr17_+_51682429 0.01 ENSDART00000004379
nucleolar protein 10
chr20_-_31308805 0.01 ENSDART00000147045
hippocalcin-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc4a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0000012 single strand break repair(GO:0000012)
0.2 0.6 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.4 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:0051000 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.1 0.2 GO:0090220 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.2 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.3 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 0.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0043393 regulation of protein binding(GO:0043393)
0.0 0.2 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.3 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling