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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxa9a+hoxa9b

Z-value: 1.74

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Transcription factors associated with hoxa9a+hoxa9b

Gene Symbol Gene ID Gene Info
ENSDARG00000056819 homeobox A9b
ENSDARG00000105013 homeobox A9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa9bdr11_v1_chr16_+_20915319_20915319-0.967.5e-11Click!
hoxa9adr11_v1_chr19_+_19750101_19750223-0.961.3e-10Click!

Activity profile of hoxa9a+hoxa9b motif

Sorted Z-values of hoxa9a+hoxa9b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_46875310 10.72 ENSDART00000154442
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr8_+_6954984 9.59 ENSDART00000145610
si:ch211-255g12.6
chr7_+_39386982 9.08 ENSDART00000146702
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr5_+_2815021 6.53 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr10_-_11385155 6.31 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr20_+_6142433 6.25 ENSDART00000054084
ENSDART00000136986
transthyretin (prealbumin, amyloidosis type I)
chr12_-_20362041 5.68 ENSDART00000184145
ENSDART00000105952
aquaporin 8a, tandem duplicate 2
chr2_-_3437862 5.62 ENSDART00000053012
cytochrome P450, family 8, subfamily B, polypeptide 1
chr8_+_47633438 5.49 ENSDART00000139096
si:ch211-251b21.1
chr9_-_22299412 5.15 ENSDART00000139101
crystallin, gamma M2d21
chr19_-_31042570 4.99 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
basic leucine zipper and W2 domains 2
chr12_-_32421046 4.89 ENSDART00000075567
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1
chr6_+_41186320 4.75 ENSDART00000025241
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr6_+_27151940 4.70 ENSDART00000088364
kinesin family member 1Aa
chr24_-_40009446 4.69 ENSDART00000087422
amine oxidase, copper containing 1
chr24_-_4765740 4.65 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr2_+_2223837 4.63 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr6_+_7444899 4.27 ENSDART00000053775
ADP-ribosylation factor 3b
chr14_+_45675306 4.24 ENSDART00000105461
retinal outer segment membrane protein 1b
chr21_+_11401247 4.16 ENSDART00000143952
carboxyl ester lipase, tandem duplicate 1
chr14_-_50892442 4.04 ENSDART00000174562
cadherin related family member 2
chr21_+_11969603 3.89 ENSDART00000142247
ENSDART00000140652
motilin-like
chr11_-_11266882 3.69 ENSDART00000020256
lengsin, lens protein with glutamine synthetase domain
chr9_-_9992697 3.62 ENSDART00000123415
UDP glucuronosyltransferase 1 family a, b
chr11_-_6188413 3.48 ENSDART00000109972
chemokine (C-C motif) ligand 44
chr16_-_17175731 3.48 ENSDART00000183057
opsin 9
chr9_-_12575776 3.41 ENSDART00000128931
ENSDART00000182695
insulin-like growth factor 2 mRNA binding protein 2a
chr25_-_30429607 3.37 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
chr8_-_39739627 3.31 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr4_+_10017049 3.29 ENSDART00000144175
coiled-coil domain containing 136b
chr13_+_19884631 3.06 ENSDART00000089533
attractin-like 1a
chr13_-_290377 3.00 ENSDART00000134963
chitin synthase 1
chr11_-_141592 2.95 ENSDART00000092787
cyclin-dependent kinase 4
chr13_+_25380432 2.93 ENSDART00000038524
glutathione S-transferase omega 1
chr25_-_7999756 2.89 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr20_-_29418620 2.86 ENSDART00000172634
ryanodine receptor 3
chr3_+_32526263 2.83 ENSDART00000150897
si:ch73-367p23.2
chr20_-_25533739 2.79 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr21_-_26089964 2.76 ENSDART00000027848
TLC domain containing 1
chr7_+_48761875 2.76 ENSDART00000003690
aggrecan a
chr13_+_52061034 2.76 ENSDART00000170383

chr5_+_32206378 2.75 ENSDART00000126873
ENSDART00000051361
myosin, heavy polypeptide 2, fast muscle specific
chr20_-_20821783 2.73 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
creatine kinase, brain b
chr8_-_53198154 2.63 ENSDART00000083416
gamma-aminobutyric acid (GABA) A receptor, delta
chr9_+_13714379 2.63 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr5_+_9382301 2.60 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr13_-_44285793 2.56 ENSDART00000167383

chr4_+_7841627 2.55 ENSDART00000037997
upper zone of growth plate and cartilage matrix associated a
chr3_+_34821327 2.49 ENSDART00000055262
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr3_+_31953145 2.44 ENSDART00000148861
potassium voltage-gated channel, Shaw-related subfamily, member 3a
chr4_+_72797711 2.39 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr12_+_16440708 2.39 ENSDART00000113810
ankyrin repeat domain 1b (cardiac muscle)
chr20_+_29587995 2.38 ENSDART00000153339
ADAM metallopeptidase domain 17b
chr10_+_24627683 2.37 ENSDART00000112652
solute carrier family 46, member 3
chr5_+_9377005 2.36 ENSDART00000124924
UDP glucuronosyltransferase 2 family, polypeptide A7
chr3_+_4997545 2.34 ENSDART00000181237

chr18_+_21122818 2.29 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr7_-_38634845 2.27 ENSDART00000173861
C1q and TNF related 4
chr2_+_16846772 2.27 ENSDART00000183564
ENSDART00000126718
family with sequence similarity 131, member A
chr8_+_14792830 2.27 ENSDART00000139972
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr24_-_11325849 2.23 ENSDART00000182485
myosin VIIA and Rab interacting protein
chr8_+_26859639 2.22 ENSDART00000133440
PR domain containing 2, with ZNF domain a
chr5_+_36932718 2.20 ENSDART00000037879
cone-rod homeobox
chr3_+_1223824 2.16 ENSDART00000065922
WBP2 N-terminal like
chr16_+_50289916 2.12 ENSDART00000168861
ENSDART00000167332
hepcidin antimicrobial peptide
chr9_-_6380653 2.11 ENSDART00000078523
esophageal cancer related gene 4a
chr19_-_6385594 2.07 ENSDART00000104950
ATPase Na+/K+ transporting subunit alpha 3a
chr15_+_8043751 2.06 ENSDART00000193701
cell adhesion molecule 2b
chr1_-_52201266 2.06 ENSDART00000143805
ENSDART00000023757
RAB3D, member RAS oncogene family, a
chr3_-_11922713 2.04 ENSDART00000150575
coronin 7
chr19_+_32321797 2.04 ENSDART00000167664
ataxin 1a
chr22_+_7480465 2.03 ENSDART00000034545
zgc:92745
chr16_+_46111849 2.03 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr14_-_31893996 2.01 ENSDART00000173222
G protein-coupled receptor 101
chr7_-_24047316 1.97 ENSDART00000184799
dehydrogenase/reductase (SDR family) member 4
chr20_-_32110882 1.96 ENSDART00000030324
glutamate receptor, metabotropic 1a
chr8_+_32402441 1.96 ENSDART00000191451
epithelial mitogen homolog (mouse)
chr3_-_48716422 1.96 ENSDART00000164979
si:ch211-114m9.1
chr21_+_39100289 1.92 ENSDART00000075958
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_-_28749640 1.92 ENSDART00000000948
coagulation factor C homolog, cochlin (Limulus polyphemus)
chr11_+_42730639 1.88 ENSDART00000165297
zgc:194981
chr4_-_27301356 1.87 ENSDART00000100444
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr11_+_6159595 1.85 ENSDART00000178367
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr9_-_2572790 1.84 ENSDART00000135076
ENSDART00000016710
secernin 3
chr12_-_26406323 1.83 ENSDART00000131896
myozenin 1b
chr21_-_25685739 1.81 ENSDART00000129619
ENSDART00000101205
phosphorylase kinase, gamma 1b (muscle)
chr9_-_12575569 1.80 ENSDART00000102419
insulin-like growth factor 2 mRNA binding protein 2a
chr1_+_54677173 1.79 ENSDART00000114705
G protein-coupled receptor, class C, group 5, member Bb
chr16_+_3982590 1.78 ENSDART00000149295
zinc finger CCCH-type containing 12A
chr17_-_6399920 1.78 ENSDART00000022010
human immunodeficiency virus type I enhancer binding protein 2b
chr7_-_20731078 1.76 ENSDART00000188267
chromodomain helicase DNA binding protein 3
chr6_-_51101834 1.76 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr7_-_4036184 1.76 ENSDART00000019949
NDRG family member 2
chr23_+_39963599 1.75 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr3_-_24980067 1.75 ENSDART00000048871
desumoylating isopeptidase 1a
chr6_-_24087279 1.75 ENSDART00000163445
zgc:109982
chr7_-_41693004 1.72 ENSDART00000121509
MAM and LDL receptor class A domain containing 1
chr11_-_9808356 1.72 ENSDART00000167465
neuroligin 1
chr16_-_27749172 1.71 ENSDART00000145198
STEAP family member 4
chr10_-_19801821 1.71 ENSDART00000148013
GDNF family receptor alpha 2b
chr16_+_12836143 1.70 ENSDART00000067741
calcium channel, voltage-dependent, gamma subunit 6b
chr14_-_2036604 1.69 ENSDART00000192446

chr16_-_46645396 1.69 ENSDART00000131485
transmembrane protein 176l.2
chr19_-_10425140 1.68 ENSDART00000145319
si:ch211-171h4.3
chr25_-_3393705 1.68 ENSDART00000163096
G protein-coupled receptor 22b
chr10_+_37145007 1.68 ENSDART00000131777
CUE domain containing 1a
chr2_+_927204 1.64 ENSDART00000165477

chr9_-_2573121 1.64 ENSDART00000181340
secernin 3
chr10_+_439692 1.58 ENSDART00000147740
zinc finger, DHHC-type containing 8a
chr7_-_4461104 1.57 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr18_+_13792490 1.56 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr4_+_21129752 1.55 ENSDART00000169764
synaptotagmin Ia
chr20_-_34754617 1.54 ENSDART00000148066
zinc finger protein 395b
chr1_-_46401385 1.53 ENSDART00000150029
ATPase phospholipid transporting 11A
chr7_-_24046999 1.53 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr20_+_52595220 1.52 ENSDART00000180610
si:dkey-235d18.5
chr7_+_69841017 1.50 ENSDART00000169107

chr5_-_71838520 1.49 ENSDART00000174396

chr16_-_17188294 1.49 ENSDART00000165883
opsin 9
chr18_+_28102620 1.48 ENSDART00000132342
KIAA1549-like b
chr17_-_51262430 1.48 ENSDART00000163222
trafficking protein particle complex 12
chr6_-_44711942 1.48 ENSDART00000055035
contactin 3b
chr2_+_6926100 1.48 ENSDART00000153289
nitric oxide synthase 1 (neuronal) adaptor protein b
chr11_-_44030962 1.47 ENSDART00000171910

chr13_+_844150 1.46 ENSDART00000058260
glutathione S-transferase, alpha tandem duplicate 1
chr5_+_9408901 1.46 ENSDART00000193364

chr23_+_3721042 1.45 ENSDART00000143323
small integral membrane protein 29
chr7_+_48761646 1.44 ENSDART00000017467
aggrecan a
chr3_-_3209432 1.43 ENSDART00000140635
si:ch211-229i14.2
chr10_+_21722892 1.42 ENSDART00000162855
protocadherin 1 gamma 13
chr11_+_44356504 1.42 ENSDART00000160678
serine/arginine-rich splicing factor 7b
chr22_-_38480186 1.41 ENSDART00000171704
heme-binding protein soul4
chr8_+_6576940 1.41 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr5_-_62940851 1.41 ENSDART00000137052
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_7546259 1.40 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr7_-_29021757 1.39 ENSDART00000086905
neuritin 1-like b
chr6_+_55032439 1.37 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
myosin binding protein Hb
chr20_-_16548912 1.37 ENSDART00000137601
checkpoint suppressor 1
chr7_-_41964877 1.35 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neuropilin (NRP) and tolloid (TLL)-like 2b
chr9_-_296169 1.33 ENSDART00000165228
kinesin family member 5A, a
chr19_-_36234185 1.33 ENSDART00000186003
CUB and Sushi multiple domains 2
chr2_-_8609653 1.33 ENSDART00000193354
ENSDART00000189489
ENSDART00000186144
si:ch211-71m22.1
chr25_-_13842618 1.32 ENSDART00000160258
mitogen-activated protein kinase 8 interacting protein 1a
chr12_+_18681477 1.32 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr17_+_50701748 1.32 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr1_+_32528097 1.31 ENSDART00000128317
neuroligin 4a
chr13_-_50002852 1.31 ENSDART00000099439
lysosomal trafficking regulator
chr10_-_35410518 1.31 ENSDART00000048430
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr20_-_8365244 1.30 ENSDART00000167102
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr22_-_11493236 1.30 ENSDART00000002691
tetraspanin 7b
chr2_-_10338759 1.29 ENSDART00000150166
ENSDART00000149584
guanine nucleotide binding protein (G protein), gamma 12a
chr16_+_12281032 1.28 ENSDART00000138638
si:dkey-26c10.5
chr9_+_29589790 1.28 ENSDART00000140388
mcf.2 cell line derived transforming sequence-like b
chr23_+_11669337 1.27 ENSDART00000131355
contactin 3a, tandem duplicate 1
chr14_-_2221877 1.27 ENSDART00000106704
protocadherin 2 alpha b 1
chr5_-_32274383 1.27 ENSDART00000122889
myosin, heavy polypeptide 1.3, skeletal muscle
chr12_-_4540564 1.27 ENSDART00000106566

chr12_+_26467847 1.27 ENSDART00000022495
nudE neurodevelopment protein 1-like 1a
chr1_+_52929185 1.26 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr17_-_52587598 1.26 ENSDART00000061497
si:ch211-173a9.6
chr21_-_7882905 1.25 ENSDART00000056561
S100 calcium binding protein Z
chr7_+_38529263 1.25 ENSDART00000109495
ENSDART00000173804
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr7_-_69853453 1.25 ENSDART00000049928
myozenin 2a
chr25_-_35497055 1.25 ENSDART00000009271
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr18_-_42172101 1.24 ENSDART00000124211
contactin 5
chr10_-_8053753 1.24 ENSDART00000162289
si:ch211-251f6.7
chr24_-_21404367 1.24 ENSDART00000152093
ATPase phospholipid transporting 8A2
chr7_+_31879986 1.23 ENSDART00000138491
myosin binding protein C, cardiac
chr11_-_6048490 1.23 ENSDART00000066164
plasmalemma vesicle associated protein b
chr13_+_12120664 1.22 ENSDART00000130007
ENSDART00000079443
gamma-aminobutyric acid type A receptor alpha2 subunit a
chr2_+_29884363 1.22 ENSDART00000139247
si:ch211-207d6.2
chr4_+_22480169 1.21 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr10_+_26571174 1.20 ENSDART00000148617
ENSDART00000112956
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr20_+_54037138 1.19 ENSDART00000143172
WD repeat domain 20b
chr11_+_36243774 1.18 ENSDART00000023323
zgc:172270
chr12_+_27213733 1.18 ENSDART00000133048
neighbor of brca1 gene 1a
chr8_-_34065573 1.18 ENSDART00000186946
pre-B-cell leukemia homeobox 3b
chr11_+_44356707 1.16 ENSDART00000165219
serine/arginine-rich splicing factor 7b
chr18_+_39649660 1.16 ENSDART00000149859
gliomedin
chr20_+_33532296 1.16 ENSDART00000153153
potassium voltage-gated channel, subfamily F, member 1a
chr23_+_40951443 1.16 ENSDART00000115161
RALBP1 associated Eps domain containing 2
chr11_-_37997419 1.15 ENSDART00000102870
solute carrier family 41 (magnesium transporter), member 1
chr24_-_23998897 1.15 ENSDART00000130053
zmp:0000000991
chr9_+_54686686 1.15 ENSDART00000066198
RAB9A, member RAS oncogene family
chr15_-_1843831 1.13 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr24_-_29586082 1.12 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr17_-_465285 1.12 ENSDART00000168718
cholinergic receptor, muscarinic 5a
chr2_-_48375342 1.11 ENSDART00000148788
period circadian clock 2
chr2_+_38554260 1.11 ENSDART00000171527
cadherin 24, type 2b
chr10_+_44924684 1.11 ENSDART00000181360
ENSDART00000170418
ENSDART00000170327
SEC14-like lipid binding 7
chr21_+_22158744 1.11 ENSDART00000101732
calpain 5b
chr2_-_43191465 1.11 ENSDART00000025254
cAMP responsive element modulator a
chr1_-_23157583 1.11 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr11_-_22997506 1.09 ENSDART00000167817
ATPase plasma membrane Ca2+ transporting 2
chr14_-_11529311 1.09 ENSDART00000127208
si:ch211-153b23.7
chr15_-_28085480 1.08 ENSDART00000060304
ENSDART00000192239
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr13_-_37620091 1.08 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
chr15_-_34845414 1.07 ENSDART00000009892
gamma-aminobutyric acid (GABA) B receptor, 1a
chr22_-_31517300 1.07 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr9_+_21820101 1.06 ENSDART00000145431
thioredoxin domain containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa9a+hoxa9b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.9 4.7 GO:0046677 response to antibiotic(GO:0046677)
0.7 2.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.7 4.2 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.7 2.8 GO:0055091 phospholipid homeostasis(GO:0055091)
0.6 6.3 GO:0072337 modified amino acid transport(GO:0072337)
0.6 3.0 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.5 5.9 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.5 3.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 2.0 GO:0099563 modification of synaptic structure(GO:0099563)
0.5 4.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 1.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 1.7 GO:0015677 copper ion import(GO:0015677)
0.4 1.9 GO:0003210 cardiac atrium formation(GO:0003210)
0.4 2.2 GO:0007343 egg activation(GO:0007343)
0.4 1.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 1.7 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.3 1.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.3 2.1 GO:0032570 response to progesterone(GO:0032570)
0.3 0.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 3.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 4.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 0.7 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.2 0.9 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.2 0.7 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 1.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 2.0 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 1.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 2.7 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 0.6 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 0.8 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 1.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 0.9 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 1.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 9.7 GO:0007602 phototransduction(GO:0007602)
0.2 1.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 9.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.7 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 0.8 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.2 1.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 2.4 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.2 0.9 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.2 2.7 GO:0014823 response to activity(GO:0014823)
0.2 2.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 1.2 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.6 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 1.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 3.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 3.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.5 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 2.0 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 3.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 7.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.8 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.5 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.1 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.1 2.3 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 5.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.3 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 6.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 7.4 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.1 13.3 GO:0007601 visual perception(GO:0007601)
0.1 1.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.1 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.2 GO:2000425 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
0.1 0.3 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 1.0 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 2.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 1.3 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.5 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 2.9 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.0 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0071938 vitamin transmembrane transport(GO:0035461) vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 3.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.5 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.1 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 3.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 1.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 2.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0002931 response to ischemia(GO:0002931)
0.0 1.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.7 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 3.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 4.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)
0.0 2.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.3 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.7 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.5 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 3.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.8 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.9 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 1.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 2.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4 2.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.4 2.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 3.0 GO:0030428 cell septum(GO:0030428)
0.3 1.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.8 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.0 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.7 GO:0010369 chromocenter(GO:0010369)
0.2 9.1 GO:0005861 troponin complex(GO:0005861)
0.2 2.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.7 GO:0044609 DBIRD complex(GO:0044609)
0.2 0.7 GO:0035339 SPOTS complex(GO:0035339)
0.2 5.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 5.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 2.6 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.8 GO:0005776 autophagosome(GO:0005776)
0.1 1.0 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 3.1 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.6 GO:0005871 kinesin complex(GO:0005871)
0.1 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 5.0 GO:0005884 actin filament(GO:0005884)
0.0 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.9 GO:0031256 leading edge membrane(GO:0031256)
0.0 1.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 4.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.6 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 2.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 2.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.0 GO:0055037 recycling endosome(GO:0055037)
0.0 1.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.4 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0030424 axon(GO:0030424)
0.0 20.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.8 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 4.5 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
1.9 5.6 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
1.6 6.3 GO:0070324 thyroid hormone binding(GO:0070324)
1.5 5.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.4 4.2 GO:0004771 sterol esterase activity(GO:0004771)
1.0 2.9 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.9 4.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 3.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.6 5.7 GO:0015250 water channel activity(GO:0015250)
0.6 2.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 2.9 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.5 2.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.5 3.7 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 2.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 2.2 GO:0050699 WW domain binding(GO:0050699)
0.4 1.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 3.0 GO:0004100 chitin synthase activity(GO:0004100)
0.3 4.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 1.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.3 3.1 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 2.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 2.0 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 0.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.7 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) sulfide:quinone oxidoreductase activity(GO:0070224)
0.2 0.7 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.2 2.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 0.6 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.2 2.7 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 9.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 2.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.9 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 0.7 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 6.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 0.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 1.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 1.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 4.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 9.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 0.6 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 5.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.8 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.1 GO:0016917 G-protein coupled GABA receptor activity(GO:0004965) GABA receptor activity(GO:0016917)
0.1 1.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.7 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.8 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0035197 siRNA binding(GO:0035197)
0.1 0.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 1.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.9 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 5.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 5.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.7 GO:0017022 myosin binding(GO:0017022)
0.0 1.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.6 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 1.1 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 1.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 4.3 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 5.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 1.4 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 7.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 4.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.8 4.8 REACTOME OPSINS Genes involved in Opsins
0.4 0.9 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.3 6.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 1.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation