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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxa2b

Z-value: 1.69

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Transcription factors associated with hoxa2b

Gene Symbol Gene ID Gene Info
ENSDARG00000023031 homeobox A2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa2bdr11_v1_chr16_+_20926673_20926673-0.918.4e-08Click!

Activity profile of hoxa2b motif

Sorted Z-values of hoxa2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_1088658 10.51 ENSDART00000162991

chr12_-_11457625 10.00 ENSDART00000012318
HtrA serine peptidase 1b
chr18_+_13792490 8.57 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr9_-_22135420 8.01 ENSDART00000184959
crystallin, gamma M2d8
chr11_+_36243774 7.95 ENSDART00000023323
zgc:172270
chr9_-_22099536 7.33 ENSDART00000101923

chr7_-_35066457 6.85 ENSDART00000058067
zgc:112160
chr5_+_37837245 6.77 ENSDART00000171617
ependymin
chr20_-_8443425 5.73 ENSDART00000083908
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr9_-_22232902 5.61 ENSDART00000101845
crystallin, gamma M2d5
chr22_-_600016 5.43 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr9_-_22135576 5.34 ENSDART00000101902
crystallin, gamma M2d8
chr25_+_19105804 5.21 ENSDART00000104414
retinaldehyde binding protein 1b
chr10_-_20453995 5.19 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
chr14_-_1565317 5.17 ENSDART00000169496

chr15_-_27972474 5.12 ENSDART00000162753

chr24_-_6898302 5.04 ENSDART00000158646
dipeptidyl-peptidase 6a
chr1_+_17676745 4.91 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr24_-_40009446 4.83 ENSDART00000087422
amine oxidase, copper containing 1
chr12_+_39685485 4.68 ENSDART00000163403

chr7_+_35075847 4.52 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr6_-_55585423 4.40 ENSDART00000157129
solute carrier family 12 (potassium/chloride transporter), member 5a
chr2_+_33541928 4.36 ENSDART00000162852

chr8_+_22931427 4.24 ENSDART00000063096
synaptophysin a
chr25_+_20215964 4.13 ENSDART00000139235
troponin T2d, cardiac
chr21_-_43079161 4.10 ENSDART00000144151
janus kinase and microtubule interacting protein 2
chr9_-_22310919 4.05 ENSDART00000108719
crystallin, gamma M2d10
chr12_-_20362041 4.02 ENSDART00000184145
ENSDART00000105952
aquaporin 8a, tandem duplicate 2
chr15_-_12270857 3.98 ENSDART00000170093
si:dkey-36i7.3
chr9_-_44939104 3.93 ENSDART00000192903
villin 1
chr6_+_41186320 3.85 ENSDART00000025241
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr11_+_25472758 3.70 ENSDART00000011178
opsin 1 (cone pigments), short-wave-sensitive 2
chr6_+_3640381 3.70 ENSDART00000172078
collagen, type XXVIII, alpha 2b
chr7_+_26326462 3.70 ENSDART00000173515
zonadhesin, like
chr15_+_45640906 3.62 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr16_-_54455573 3.62 ENSDART00000075275
pyruvate kinase L/R
chr18_-_898870 3.47 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr7_-_4461104 3.42 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr17_-_200316 3.40 ENSDART00000190561

chr24_-_6897884 3.39 ENSDART00000080766
dipeptidyl-peptidase 6a
chr12_-_25916530 3.38 ENSDART00000186386
synuclein, gamma b (breast cancer-specific protein 1)
chr17_+_40684 3.34 ENSDART00000164231

chr14_+_35237613 3.30 ENSDART00000163465
early B cell factor 3a
chr8_+_43053519 3.29 ENSDART00000147178
prion protein a
chr3_+_4997545 3.27 ENSDART00000181237

chr25_+_4760489 3.27 ENSDART00000167399

chr16_+_12022543 3.16 ENSDART00000012673
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr25_+_20216159 3.14 ENSDART00000048642
troponin T2d, cardiac
chr9_+_22003942 3.13 ENSDART00000091013
si:dkey-57a22.15
chr17_-_6399920 3.11 ENSDART00000022010
human immunodeficiency virus type I enhancer binding protein 2b
chr20_-_34868814 3.09 ENSDART00000153049
stathmin-like 4
chr10_+_439692 3.04 ENSDART00000147740
zinc finger, DHHC-type containing 8a
chr21_+_40092301 2.97 ENSDART00000145150
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr17_-_20897407 2.95 ENSDART00000149481
ankyrin 3b
chr8_+_21376290 2.94 ENSDART00000136765
elastase 2
chr14_-_2199573 2.91 ENSDART00000124485
protocadherin 2 alpha b 8
chr4_+_21129752 2.89 ENSDART00000169764
synaptotagmin Ia
chr16_-_13612650 2.88 ENSDART00000080372
D site albumin promoter binding protein b
chr23_+_44881020 2.87 ENSDART00000149355
si:ch73-361h17.1
chr11_-_7320211 2.83 ENSDART00000091664
adenomatosis polyposis coli 2
chr18_+_1768804 2.82 ENSDART00000167477

chr4_+_26496489 2.76 ENSDART00000160652
IQ motif and Sec7 domain 3a
chr2_-_28671139 2.76 ENSDART00000165272
ENSDART00000164657
7-dehydrocholesterol reductase
chr25_-_35497055 2.73 ENSDART00000009271
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr21_-_40174647 2.72 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
solute carrier organic anion transporter family, member 2B1
chr13_-_51065048 2.71 ENSDART00000168085

chr25_+_15354095 2.54 ENSDART00000090397
KIAA1549-like a
chr23_-_45504991 2.50 ENSDART00000148761
collagen type XXIV alpha 1
chr18_-_42785469 2.50 ENSDART00000024768
tetratricopeptide repeat domain 36
chr5_-_50992690 2.49 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
3-hydroxy-3-methylglutaryl-CoA reductase a
chr24_-_29822913 2.47 ENSDART00000160929
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr12_-_4346085 2.46 ENSDART00000112433
carbonic anhydrase XV c
chr22_+_1123873 2.44 ENSDART00000137708
si:ch1073-181h11.2
chr13_+_15838151 2.43 ENSDART00000008987
kinesin light chain 1a
chr5_+_44654535 2.41 ENSDART00000182190
ENSDART00000181872
death-associated protein kinase 1
chr1_+_29281764 2.38 ENSDART00000112106
family with sequence similarity 155, member A
chr7_+_427503 2.37 ENSDART00000185942
neurexin 2
chr1_-_51465730 2.35 ENSDART00000074284
sprouty-related, EVH1 domain containing 2a
chr12_+_48241841 2.34 ENSDART00000168616
pyrophosphatase (inorganic) 1a
chr2_-_45630823 2.34 ENSDART00000183553

chr4_+_17279966 2.27 ENSDART00000067005
ENSDART00000137487
branched chain amino-acid transaminase 1, cytosolic
chr2_+_24199276 2.27 ENSDART00000140575
microtubule associated protein 4 like
chr22_-_33679277 2.27 ENSDART00000169948

chr15_+_45643787 2.26 ENSDART00000055995
ENSDART00000157750
S-antigen; retina and pineal gland (arrestin) b
chr19_+_46824723 2.25 ENSDART00000158620

chr2_-_31634978 2.24 ENSDART00000135668
si:ch211-106h4.9
chr7_-_36096582 2.22 ENSDART00000188507

chr20_-_29420713 2.22 ENSDART00000147464
ryanodine receptor 3
chr2_+_17451656 2.21 ENSDART00000163620

chr19_+_4443285 2.21 ENSDART00000162683
trafficking protein particle complex 9
chr14_+_15155684 2.20 ENSDART00000167966
zgc:158852
chr18_-_7677208 2.19 ENSDART00000092456
SH3 and multiple ankyrin repeat domains 3a
chr12_-_4028079 2.16 ENSDART00000128676
si:ch211-180a12.2
chr4_-_16333944 2.15 ENSDART00000079523
epiphycan
chr4_+_40427249 2.15 ENSDART00000151927
si:ch211-218h8.3
chr23_+_44611864 2.13 ENSDART00000145905
ENSDART00000132361
enolase 3, (beta, muscle)
chr21_+_11969603 2.13 ENSDART00000142247
ENSDART00000140652
motilin-like
chr4_-_42408339 2.11 ENSDART00000172612
si:ch211-59d8.3
chr16_+_10776688 2.11 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr22_+_20208185 2.11 ENSDART00000142748
si:dkey-110c1.7
chr14_-_36378494 2.10 ENSDART00000058503
glycoprotein M6Aa
chr23_+_5490854 2.10 ENSDART00000175403
tubby like protein 1a
chr25_+_7494181 2.09 ENSDART00000165005
catalase
chr10_+_375042 2.08 ENSDART00000171854
si:ch1073-303d10.1
chr17_-_20897250 2.08 ENSDART00000088106
ankyrin 3b
chr25_-_30047477 2.08 ENSDART00000164859

chr12_+_48634927 2.05 ENSDART00000168441
zgc:165653
chr5_+_36932718 2.03 ENSDART00000037879
cone-rod homeobox
chr15_+_16521785 2.02 ENSDART00000062191
polypeptide N-acetylgalactosaminyltransferase 17
chr4_+_76575585 2.01 ENSDART00000131588
membrane-spanning 4-domains, subfamily A, member 17A.11
chr24_-_29997145 2.01 ENSDART00000135094
palmdelphin b
chr10_-_22249444 1.99 ENSDART00000148831
fibroblast growth factor 11b
chr17_-_28749640 1.99 ENSDART00000000948
coagulation factor C homolog, cochlin (Limulus polyphemus)
chr22_-_24297510 1.98 ENSDART00000163297
si:ch211-117l17.6
chr15_+_42933236 1.97 ENSDART00000167763
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr9_+_44721808 1.97 ENSDART00000190578
NCK-associated protein 1
chr23_+_9867483 1.95 ENSDART00000023099
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr8_+_49975160 1.95 ENSDART00000156403
ENSDART00000080135
glutamine--fructose-6-phosphate transaminase 1
chr5_+_4332220 1.95 ENSDART00000051699
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr2_-_38000276 1.93 ENSDART00000034790
Purkinje cell protein 4 like 1
chr14_-_31893996 1.92 ENSDART00000173222
G protein-coupled receptor 101
chr6_+_9175886 1.92 ENSDART00000165333
si:ch211-207l14.1
chr9_-_51370293 1.91 ENSDART00000084806
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr2_+_24199073 1.90 ENSDART00000144110
microtubule associated protein 4 like
chr10_-_29809105 1.89 ENSDART00000162231
si:ch73-261i21.5
chr2_+_45636034 1.89 ENSDART00000142230
fibronectin type III domain containing 7, related sequence 3
chr5_-_18446483 1.89 ENSDART00000180027
si:dkey-215k6.1
chr5_+_32221755 1.87 ENSDART00000125917
myosin heavy chain 4
chr23_-_16692312 1.86 ENSDART00000046784
FK506 binding protein 1Ab
chr25_-_207214 1.85 ENSDART00000193448

chr11_-_4220167 1.85 ENSDART00000185406
si:ch211-236d3.4
chr13_-_290377 1.83 ENSDART00000134963
chitin synthase 1
chr7_-_13882988 1.82 ENSDART00000169828
retinaldehyde binding protein 1a
chr17_-_15640467 1.81 ENSDART00000014210
fucosyltransferase 9a
chr25_+_15841670 1.80 ENSDART00000049992
synaptotagmin IXb
chr20_+_23238833 1.79 ENSDART00000074167
OCIA domain containing 2
chr25_-_13363286 1.79 ENSDART00000163735
ENSDART00000169119
NDRG family member 4
chr2_+_21128391 1.76 ENSDART00000136814
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr7_-_2129076 1.76 ENSDART00000182385
si:cabz01007807.1
chr14_+_2478994 1.75 ENSDART00000170538

chr2_+_52232630 1.75 ENSDART00000006216
phospholipid phosphatase 2a
chr14_+_15231097 1.75 ENSDART00000172430
si:dkey-203a12.3
chr16_+_46111849 1.73 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr25_+_19106574 1.73 ENSDART00000067332
retinaldehyde binding protein 1b
chr16_-_45058919 1.72 ENSDART00000177134
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr11_-_44030962 1.72 ENSDART00000171910

chr1_-_43963441 1.71 ENSDART00000137646
odontogenic, ameloblast associated
chr24_+_5840258 1.71 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr18_-_8877077 1.71 ENSDART00000137266
si:dkey-95h12.2
chr6_+_4255319 1.70 ENSDART00000170351
neurobeachin-like 1
chr22_+_34701848 1.70 ENSDART00000082066
ATPase H+ transporting V0 subunit e2
chr6_+_54538948 1.69 ENSDART00000149270
tubby like protein 1b
chr17_+_5793248 1.69 ENSDART00000153743
retinitis pigmentosa 1-like 1a
chr8_-_10045043 1.67 ENSDART00000081917
si:dkey-8e10.3
chr16_-_49746832 1.66 ENSDART00000166423
zinc finger protein 385D
chr1_+_11881559 1.65 ENSDART00000166981
sorting nexin 8b
chr15_-_7598294 1.65 ENSDART00000165898
glucan (1,4-alpha-), branching enzyme 1b
chr6_-_16406210 1.64 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr15_-_7598542 1.63 ENSDART00000173092
glucan (1,4-alpha-), branching enzyme 1b
chr3_-_32818607 1.63 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr1_-_26023678 1.62 ENSDART00000054202
si:ch211-145b13.5
chr13_+_9432501 1.61 ENSDART00000058064
zgc:123321
chr18_+_28102620 1.61 ENSDART00000132342
KIAA1549-like b
chr17_-_26507289 1.59 ENSDART00000155616
coiled-coil serine-rich protein 2a
chr4_+_47736069 1.58 ENSDART00000193329
si:ch211-196f19.1
chr8_-_44015210 1.58 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
RIMS binding protein 2
RIMS binding protein 2
chr18_+_783936 1.57 ENSDART00000193357
ribonuclease P and MRP subunit p25, b
chr12_-_26406323 1.57 ENSDART00000131896
myozenin 1b
chr19_-_11208782 1.54 ENSDART00000044426
ENSDART00000189754
si:dkey-240h12.4
chr18_+_16963881 1.53 ENSDART00000147583
si:ch211-242e8.1
chr8_-_10048059 1.52 ENSDART00000138411
si:dkey-8e10.3
chr1_-_55044256 1.52 ENSDART00000165505
ENSDART00000167536
ENSDART00000170001
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr3_-_48716422 1.51 ENSDART00000164979
si:ch211-114m9.1
chr19_+_37925616 1.51 ENSDART00000148348
neurexophilin 1
chr8_-_17771755 1.49 ENSDART00000063592
protein kinase C, zeta
chr18_+_16960966 1.48 ENSDART00000193969
ENSDART00000100131
si:ch211-242e8.1
chr8_+_50983551 1.48 ENSDART00000142061
si:dkey-32e23.4
chr2_-_19109304 1.48 ENSDART00000168028
si:dkey-225f23.5
chr13_-_23756700 1.48 ENSDART00000057612
regulator of G protein signaling 17
chr13_-_1349922 1.48 ENSDART00000140970
si:ch73-52p7.1
chr4_-_14926637 1.47 ENSDART00000110199
PR domain containing 4
chr24_+_37370064 1.46 ENSDART00000185870
si:ch211-183d21.3
chr18_+_10840071 1.45 ENSDART00000014496
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr8_-_34051548 1.45 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr7_+_41295974 1.45 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
chr12_-_3453589 1.45 ENSDART00000175918

chr12_+_6195191 1.44 ENSDART00000043236
ENSDART00000186420
protein kinase, cGMP-dependent, type Ib
chr16_+_12281032 1.43 ENSDART00000138638
si:dkey-26c10.5
chr8_-_31403938 1.43 ENSDART00000159168
NIM1 serine/threonine protein kinase
chr3_-_35800221 1.43 ENSDART00000031390
CASK interacting protein 1
chr5_+_61301525 1.42 ENSDART00000128773
double C2-like domains, beta
chr1_-_9228007 1.42 ENSDART00000147277
ENSDART00000135219
guanine nucleotide binding protein (G protein), gamma 13a
chr9_-_3653259 1.41 ENSDART00000140425
ENSDART00000025332
glutamate decarboxylase 1a
chr14_+_34486629 1.41 ENSDART00000131861
thymosin beta 2
chr17_+_8183393 1.41 ENSDART00000155957
tubby like protein 4b
chr8_+_36509885 1.41 ENSDART00000109530
solute carrier family 7, member 4
chr4_+_7391110 1.40 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr22_+_15438513 1.39 ENSDART00000010846
glypican 5b
chr7_+_35229645 1.39 ENSDART00000144327
tubulin polymerization-promoting protein family member 3
chr8_-_53198154 1.39 ENSDART00000083416
gamma-aminobutyric acid (GABA) A receptor, delta

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
1.1 8.6 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
1.0 3.9 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
1.0 4.8 GO:0046677 response to antibiotic(GO:0046677)
0.7 5.7 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.7 2.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.6 2.4 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.6 1.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.6 5.8 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.6 2.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.5 5.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.5 1.9 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.4 5.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.4 0.4 GO:0051580 regulation of neurotransmitter uptake(GO:0051580)
0.4 2.5 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 2.4 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.4 1.2 GO:0006089 lactate metabolic process(GO:0006089)
0.4 1.5 GO:0090330 regulation of platelet activation(GO:0010543) regulation of platelet aggregation(GO:0090330)
0.4 1.5 GO:0099563 modification of synaptic structure(GO:0099563)
0.4 1.8 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.4 9.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.4 1.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.4 2.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.3 1.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 9.1 GO:0007634 optokinetic behavior(GO:0007634)
0.3 3.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 1.3 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.3 2.2 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.3 1.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 1.2 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.3 0.9 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.3 0.3 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.3 8.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.3 2.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 0.8 GO:0034214 protein hexamerization(GO:0034214)
0.3 3.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.0 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 0.7 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.2 2.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.2 1.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 1.4 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.2 0.7 GO:0033212 iron assimilation(GO:0033212)
0.2 0.7 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.2 2.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.2 GO:0032648 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.2 1.0 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 1.0 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 3.7 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 2.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 4.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 25.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 1.3 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 2.5 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 1.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 8.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.7 GO:0015677 copper ion import(GO:0015677)
0.2 2.0 GO:0050909 sensory perception of taste(GO:0050909)
0.2 0.5 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.5 GO:0002076 osteoblast development(GO:0002076)
0.2 8.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.2 0.7 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 2.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 1.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 4.8 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.2 0.8 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.2 1.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 2.0 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.1 1.6 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.9 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 1.6 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 1.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 3.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 3.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 1.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.4 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 1.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 3.3 GO:0051283 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.1 2.1 GO:0046688 response to copper ion(GO:0046688)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.4 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 2.7 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 2.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 1.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.4 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 5.3 GO:0006096 glycolytic process(GO:0006096)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 3.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.4 GO:0036065 fucosylation(GO:0036065)
0.1 1.5 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.1 3.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 2.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.2 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.5 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.1 0.6 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.8 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 1.4 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.2 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.7 GO:0043217 myelin maintenance(GO:0043217)
0.1 0.4 GO:0009118 regulation of oxidative phosphorylation(GO:0002082) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.1 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.9 GO:0007602 phototransduction(GO:0007602)
0.1 1.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 3.4 GO:0061512 protein localization to cilium(GO:0061512)
0.1 2.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 0.5 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) cellular response to leucine starvation(GO:1990253)
0.1 2.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 1.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 1.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 8.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 3.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 3.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 1.0 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 2.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 2.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.2 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.5 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.1 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.7 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.4 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.1 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0046323 glucose import(GO:0046323)
0.1 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 1.2 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 1.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 3.8 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 5.4 GO:0006814 sodium ion transport(GO:0006814)
0.0 3.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.5 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 1.4 GO:0046785 microtubule polymerization(GO:0046785)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.8 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.4 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 1.1 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 2.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.3 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 2.0 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.5 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.3 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 1.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0009261 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.0 0.5 GO:0021986 habenula development(GO:0021986)
0.0 1.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 1.1 GO:0007605 sensory perception of sound(GO:0007605)
0.0 2.1 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.7 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 0.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 1.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.0 0.6 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 2.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0030168 platelet activation(GO:0030168)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.4 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 1.7 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.6 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 0.0 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.9 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.6 GO:0006956 complement activation(GO:0006956)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0031056 regulation of histone modification(GO:0031056)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.3 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.4 GO:0071216 cellular response to biotic stimulus(GO:0071216) cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0032094 response to food(GO:0032094)
0.0 0.5 GO:1901214 regulation of neuron death(GO:1901214)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.8 3.9 GO:0032433 filopodium tip(GO:0032433)
0.7 4.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.6 2.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.4 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.4 2.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 14.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 1.8 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.3 3.4 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.4 GO:0042583 chromaffin granule(GO:0042583)
0.3 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.0 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 1.8 GO:0031045 dense core granule(GO:0031045)
0.3 1.5 GO:0000938 GARP complex(GO:0000938)
0.2 9.9 GO:0005861 troponin complex(GO:0005861)
0.2 1.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 9.2 GO:0016342 catenin complex(GO:0016342)
0.2 1.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 4.8 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.2 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 5.5 GO:0043679 axon terminus(GO:0043679)
0.1 5.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 8.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 9.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.3 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 5.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 2.5 GO:0034703 cation channel complex(GO:0034703)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 3.6 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 22.3 GO:0005576 extracellular region(GO:0005576)
0.0 4.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 16.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
1.1 3.4 GO:1903136 cuprous ion binding(GO:1903136)
1.0 4.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 3.3 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.8 2.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.7 2.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.7 2.7 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.7 7.3 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.6 2.5 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.6 3.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 1.8 GO:0070097 delta-catenin binding(GO:0070097)
0.6 5.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.6 2.3 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 4.0 GO:0015250 water channel activity(GO:0015250)
0.4 2.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 7.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 1.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 3.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 11.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 1.2 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.4 2.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.4 1.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.3 1.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3 27.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 2.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 0.9 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.3 2.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 2.0 GO:0019809 spermidine binding(GO:0019809)
0.3 1.1 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.3 4.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.3 1.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.3 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 2.1 GO:0004096 catalase activity(GO:0004096)
0.2 2.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 2.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 3.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 1.0 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 0.8 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 0.6 GO:0046978 TAP1 binding(GO:0046978)
0.2 3.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 3.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.4 GO:0034452 dynactin binding(GO:0034452)
0.2 8.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 0.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 1.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 6.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 12.9 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.2 1.6 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 1.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 2.0 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.2 1.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.6 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 4.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 1.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.4 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.5 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.4 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 5.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 2.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.6 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.1 1.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 8.3 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 5.0 GO:0050661 NADP binding(GO:0050661)
0.1 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.3 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.5 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 0.4 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 17.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 9.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 2.9 GO:0017022 myosin binding(GO:0017022)
0.1 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 2.8 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.7 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 7.5 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 8.2 GO:0019900 kinase binding(GO:0019900)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.7 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159) protein complex scaffold(GO:0032947)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.9 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 2.5 GO:0060090 binding, bridging(GO:0060090)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 7.4 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.0 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 2.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.3 PID FOXO PATHWAY FoxO family signaling
0.1 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 3.9 REACTOME OPSINS Genes involved in Opsins
0.4 2.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 8.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 8.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 2.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 0.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 2.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 4.9 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis