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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hnf4g

Z-value: 0.65

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Transcription factors associated with hnf4g

Gene Symbol Gene ID Gene Info
hnf4g
ENSDARG00000071565 hepatocyte nuclear factor 4, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf4gdr11_v1_chr24_-_23671709_236717090.589.4e-03Click!

Activity profile of hnf4g motif

Sorted Z-values of hnf4g motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_1138802 2.01 ENSDART00000191130
ENSDART00000187308
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr9_+_1138323 1.79 ENSDART00000190352
ENSDART00000190387
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr20_-_25522911 1.72 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr8_-_20838342 1.55 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr22_-_31517300 1.43 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr17_+_50701748 1.43 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr13_-_303137 1.37 ENSDART00000099131
chs1
chitin synthase 1
chr9_-_44953664 1.28 ENSDART00000188558
ENSDART00000185210
vil1
villin 1
chr23_+_19790962 1.27 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr12_+_22607761 1.05 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr2_+_37897079 1.01 ENSDART00000141784
tep1
telomerase-associated protein 1
chr23_-_43595956 0.98 ENSDART00000162186
itchb
itchy E3 ubiquitin protein ligase b
chr10_+_45128375 0.98 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr6_+_59029485 0.85 ENSDART00000050140
CABZ01088367.1

chr12_-_33706726 0.83 ENSDART00000153135
myo15b
myosin XVB
chr8_+_53464216 0.80 ENSDART00000169514
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr15_-_41700406 0.77 ENSDART00000181460
si:ch211-276c2.4
si:ch211-276c2.4
chr24_-_32150276 0.75 ENSDART00000166212
cubn
cubilin (intrinsic factor-cobalamin receptor)
chr3_+_16762483 0.72 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr2_+_11670270 0.70 ENSDART00000100524
ftr01
finTRIM family, member 1
chr8_+_14778292 0.70 ENSDART00000089971
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr6_-_607063 0.68 ENSDART00000189900
lgals2b
lectin, galactoside-binding, soluble, 2b
chr17_+_20173882 0.67 ENSDART00000155379
si:ch211-248a14.8
si:ch211-248a14.8
chr21_-_43474012 0.66 ENSDART00000065104
tmem185
transmembrane protein 185
chr3_-_27868183 0.64 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr7_-_24520866 0.61 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr18_-_9016161 0.59 ENSDART00000189888
grm3
glutamate receptor, metabotropic 3
chr20_+_43379029 0.59 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr4_+_7888047 0.58 ENSDART00000104676
camk1da
calcium/calmodulin-dependent protein kinase 1Da
chr5_-_69180587 0.57 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr13_-_50309969 0.56 ENSDART00000191597
CU928131.1

chr19_-_22387141 0.54 ENSDART00000151234
eppk1
epiplakin 1
chr1_+_47585700 0.54 ENSDART00000153746
ENSDART00000084457
sh3pxd2aa
SH3 and PX domains 2Aa
chr17_-_6076266 0.53 ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr17_-_6076084 0.51 ENSDART00000058890
ephx2
epoxide hydrolase 2, cytoplasmic
chr6_-_46474483 0.46 ENSDART00000155761
rdh20
retinol dehydrogenase 20
chr5_+_42467867 0.46 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr22_+_2844865 0.43 ENSDART00000139123
si:dkey-20i20.4
si:dkey-20i20.4
chr8_+_47188154 0.43 ENSDART00000137319
si:dkeyp-100a1.6
si:dkeyp-100a1.6
chr17_+_20174044 0.41 ENSDART00000156028
si:ch211-248a14.8
si:ch211-248a14.8
chr13_+_50375800 0.41 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr13_-_37254777 0.41 ENSDART00000139734
syne2b
spectrin repeat containing, nuclear envelope 2b
chr21_-_27443995 0.40 ENSDART00000003508
bfb
complement component bfb
chr14_-_16810401 0.40 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr4_-_17725008 0.40 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr19_+_1003332 0.39 ENSDART00000081779
zdhhc3b
zinc finger, DHHC-type containing 3b
chr20_-_46694573 0.39 ENSDART00000182557
AL929435.2

chr6_+_27624023 0.39 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr16_+_11623956 0.39 ENSDART00000137788
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr9_+_48415043 0.39 ENSDART00000159930
lrp2a
low density lipoprotein receptor-related protein 2a
chr20_-_49657134 0.38 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr11_+_33284837 0.38 ENSDART00000166239
ENSDART00000111412
nkpd1
NTPase, KAP family P-loop domain containing 1
chr1_-_37383741 0.38 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr16_+_11660839 0.38 ENSDART00000193911
ENSDART00000143683
si:dkey-250k15.10
si:dkey-250k15.10
chr11_-_5563498 0.37 ENSDART00000160835
pex11g
peroxisomal biogenesis factor 11 gamma
chr16_+_9495583 0.36 ENSDART00000150750
ENSDART00000150457
pimr208
Pim proto-oncogene, serine/threonine kinase, related 208
chr5_-_69180227 0.35 ENSDART00000154816
zgc:171967
zgc:171967
chr7_-_29115772 0.34 ENSDART00000076386
fbxl8
F-box and leucine-rich repeat protein 8
chr21_-_5879897 0.34 ENSDART00000184034
rpl35
ribosomal protein L35
chr7_+_30823749 0.33 ENSDART00000085661
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr15_-_30857350 0.33 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr21_-_11856143 0.33 ENSDART00000151204
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr24_-_39567 0.33 ENSDART00000055488
cdh7b
cadherin 7b
chr19_-_28360033 0.32 ENSDART00000186994
si:dkey-261i16.5
si:dkey-261i16.5
chr6_-_49769100 0.32 ENSDART00000148853
si:dkey-249d8.1
si:dkey-249d8.1
chr22_-_20376488 0.31 ENSDART00000140187
zbtb7a
zinc finger and BTB domain containing 7a
chr8_-_49207319 0.30 ENSDART00000022870
fam110a
family with sequence similarity 110, member A
chr14_+_9009600 0.28 ENSDART00000133904
si:ch211-274f20.2
si:ch211-274f20.2
chr5_+_37069605 0.28 ENSDART00000161977
si:dkeyp-110c7.4
si:dkeyp-110c7.4
chr3_-_8765165 0.27 ENSDART00000191131
CABZ01058333.1

chr9_+_29994439 0.27 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr13_-_40726865 0.27 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr10_-_43568239 0.26 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
mef2ca
myocyte enhancer factor 2ca
chr1_-_37383539 0.26 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr11_+_11152214 0.25 ENSDART00000148030
ly75
lymphocyte antigen 75
chr5_-_30080332 0.25 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr6_-_56103718 0.24 ENSDART00000191002
gcnt7
glucosaminyl (N-acetyl) transferase family member 7
chr15_-_2632891 0.24 ENSDART00000081840
cldnj
claudin j
chr7_+_24520518 0.23 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr10_-_21953643 0.23 ENSDART00000188921
ENSDART00000193569
FO744833.2

chr18_+_33725576 0.22 ENSDART00000146816
si:dkey-145c18.5
si:dkey-145c18.5
chr6_+_27339962 0.22 ENSDART00000193726
klhl30
kelch-like family member 30
chr13_+_21779975 0.22 ENSDART00000021556
si:ch211-51a6.2
si:ch211-51a6.2
chr22_+_1300587 0.21 ENSDART00000124161
si:ch73-138e16.5
si:ch73-138e16.5
chr7_-_59514547 0.21 ENSDART00000168457
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr16_+_5251768 0.20 ENSDART00000144558
plecb
plectin b
chr5_-_65319387 0.19 ENSDART00000164649
col27a1b
collagen, type XXVII, alpha 1b
chr10_+_41765944 0.19 ENSDART00000171484
rnf34b
ring finger protein 34b
chr21_-_43428040 0.19 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr9_+_29616854 0.19 ENSDART00000033902
ENSDART00000143493
phf11
PHD finger protein 11
chr12_+_2455429 0.18 ENSDART00000182929
ARHGAP22
si:dkey-191m6.4
chr20_+_23238833 0.17 ENSDART00000074167
ociad2
OCIA domain containing 2
chr2_+_13050225 0.15 ENSDART00000182237
BX324233.1

chr15_-_16012963 0.14 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr10_-_39055620 0.13 ENSDART00000187437
igsf5a
immunoglobulin superfamily, member 5a
chr4_-_170120 0.13 ENSDART00000171333
eps8
epidermal growth factor receptor pathway substrate 8
chr14_-_16379843 0.13 ENSDART00000090711
ltc4s
leukotriene C4 synthase
chr5_-_62317496 0.13 ENSDART00000180089
zgc:85789
zgc:85789
chr1_-_52292235 0.13 ENSDART00000132638
si:dkey-121b10.7
si:dkey-121b10.7
chr22_+_19407531 0.12 ENSDART00000141060
si:dkey-78l4.2
si:dkey-78l4.2
chr7_+_17229282 0.12 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr3_+_12764894 0.11 ENSDART00000166071
cyp2k16
cytochrome P450, family 2, subfamily K, polypeptide16
chr17_+_15297398 0.11 ENSDART00000156574
si:ch211-270g19.5
si:ch211-270g19.5
chr11_+_19068442 0.10 ENSDART00000171766
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr6_+_11026866 0.10 ENSDART00000189619
abcc6a
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
chr1_+_41690402 0.09 ENSDART00000177298
fbxo41
F-box protein 41
chr4_-_72468168 0.09 ENSDART00000182995
ENSDART00000174067
CR788316.1

chr5_-_50640171 0.09 ENSDART00000183353
mctp1a
multiple C2 domains, transmembrane 1a
chr4_+_11172964 0.09 ENSDART00000193598
ENSDART00000138661
tspan11
tetraspanin 11
chr1_-_57172294 0.07 ENSDART00000063774
rac1l
Rac family small GTPase 1, like
chr24_+_20960216 0.07 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr15_+_3825117 0.07 ENSDART00000183315
CABZ01061591.1

chr8_+_23390844 0.05 ENSDART00000184556
si:dkey-16n15.6
si:dkey-16n15.6
chr16_+_25809235 0.04 ENSDART00000181196
irgq1
immunity-related GTPase family, q1
chr7_-_39738460 0.03 ENSDART00000052201
ccdc96
coiled-coil domain containing 96
chr12_+_33916939 0.03 ENSDART00000149292
trim8b
tripartite motif containing 8b
chr6_+_18298444 0.02 ENSDART00000166018
card14
caspase recruitment domain family, member 14
chr8_+_24745041 0.00 ENSDART00000148872
slc16a4
solute carrier family 16, member 4
chr24_+_7828097 0.00 ENSDART00000134975
zgc:101569
zgc:101569

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4g

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 GO:0006857 oligopeptide transport(GO:0006857)
0.3 1.3 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.3 1.4 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.6 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.3 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 1.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.4 GO:0070293 renal absorption(GO:0070293)
0.0 1.0 GO:0060841 venous blood vessel development(GO:0060841)
0.0 1.4 GO:0072348 sulfur compound transport(GO:0072348)
0.0 1.5 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 1.8 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 1.0 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.2 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 1.5 GO:0070509 calcium ion import(GO:0070509)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0032433 filopodium tip(GO:0032433)
0.2 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.4 GO:0030428 cell septum(GO:0030428)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.3 1.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.4 GO:0004100 chitin synthase activity(GO:0004100)
0.1 0.7 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.3 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.6 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 1.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC