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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hmx4

Z-value: 1.68

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Transcription factors associated with hmx4

Gene Symbol Gene ID Gene Info
ENSDARG00000007941 H6 family homeobox 4
ENSDARG00000115000 H6 family homeobox 4
ENSDARG00000116208 H6 family homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmx4dr11_v1_chr1_-_40911332_40911332-0.691.1e-03Click!

Activity profile of hmx4 motif

Sorted Z-values of hmx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_992458 14.21 ENSDART00000114655
beaded filament structural protein 1
chr22_+_7439476 7.44 ENSDART00000021594
ENSDART00000063389
zgc:92041
chr21_+_30043054 6.62 ENSDART00000065448
fatty acid binding protein 6, ileal (gastrotropin)
chr22_+_7439186 5.97 ENSDART00000190667
zgc:92041
chr3_+_31039923 5.27 ENSDART00000147706
cytochrome c oxidase subunit VIa polypeptide 2
chr22_+_7497319 5.00 ENSDART00000034564
zgc:92511
chr19_+_233143 4.94 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr13_+_3667230 4.90 ENSDART00000131553
ENSDART00000189841
ENSDART00000183554
ENSDART00000018737
QKI, KH domain containing, RNA binding b
chr16_-_26074529 4.83 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr15_+_45640906 4.64 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr3_-_5067585 4.50 ENSDART00000169609
thyrotrophic embryonic factor b
chr18_-_46763170 4.23 ENSDART00000171880
delta/notch-like EGF repeat containing
chr2_-_49978227 4.09 ENSDART00000142835
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b
chr13_-_7031033 3.88 ENSDART00000193211

chr8_-_21184759 3.86 ENSDART00000139257
glutaminase 2a (liver, mitochondrial)
chr7_+_13040312 3.73 ENSDART00000171949
ENSDART00000101231
synaptotagmin VIIb
chr19_-_12322356 3.69 ENSDART00000016128
neurocalcin delta b
chr12_-_17810543 3.58 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr20_-_29418620 3.58 ENSDART00000172634
ryanodine receptor 3
chr7_-_10606 3.49 ENSDART00000192650
ENSDART00000186761

chr1_-_14233815 3.33 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr16_+_12022543 3.22 ENSDART00000012673
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr1_+_45839927 3.17 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr12_-_22524388 3.15 ENSDART00000020942
sex hormone-binding globulin
chr5_-_68058168 3.13 ENSDART00000177026
ring finger protein 167
chr4_+_10017049 3.11 ENSDART00000144175
coiled-coil domain containing 136b
chr23_+_44307996 3.02 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr1_+_8662530 3.00 ENSDART00000054989
fascin actin-bundling protein 1b
chr2_-_1279387 2.98 ENSDART00000192210

chr8_-_43997538 2.97 ENSDART00000186449
RIMS binding protein 2
chr1_-_14234076 2.91 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr12_+_1286642 2.91 ENSDART00000157467
phosphatidylethanolamine N-methyltransferase
chr19_+_5674907 2.84 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr11_-_2250767 2.80 ENSDART00000018131
heterogeneous nuclear ribonucleoprotein A1a
chr9_-_44642108 2.79 ENSDART00000086202
phosphodiesterase 1A, calmodulin-dependent
chr25_-_225964 2.71 ENSDART00000193424

chr10_-_7671219 2.66 ENSDART00000159330
prenylcysteine oxidase 1
chr13_-_3370638 2.61 ENSDART00000029649
parkin RBR E3 ubiquitin protein ligase
chr19_-_13774502 2.58 ENSDART00000159711
erythrocyte membrane protein band 4.1a
chr23_+_19564392 2.57 ENSDART00000144746
ATPase H+ transporting accessory protein 1 like b
chr3_-_28209001 2.56 ENSDART00000151178
RNA binding fox-1 homolog 1
chr25_+_35774544 2.49 ENSDART00000034737
ENSDART00000188162
copine VIII
chr9_+_46644633 2.48 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr16_+_46148990 2.45 ENSDART00000083919
synaptic vesicle glycoprotein 2A
chr20_+_36820965 2.44 ENSDART00000153085
ENSDART00000062935
hdc homolog, cell cycle regulator
chr1_-_25911292 2.42 ENSDART00000145012
ubiquitin specific peptidase 53b
chr19_+_43669122 2.42 ENSDART00000139151
si:ch211-193k19.1
chr23_-_26532696 2.41 ENSDART00000124811
ENSDART00000180274
si:dkey-205h13.2
chr9_+_8761099 2.40 ENSDART00000159077
collagen, type IV, alpha 2
chr8_+_7144066 2.39 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr21_-_23475361 2.39 ENSDART00000156658
ENSDART00000157454
neural cell adhesion molecule 1a
chr4_+_3287819 2.30 ENSDART00000168633

chr3_-_60571218 2.30 ENSDART00000178981
si:ch73-366l1.5
chr18_+_39067575 2.22 ENSDART00000077724
guanine nucleotide binding protein (G protein), beta 5b
chr12_+_22607761 2.20 ENSDART00000153112
si:dkey-219e21.2
chr22_-_12160283 2.20 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr16_+_5774977 2.19 ENSDART00000134202
cholecystokinin a
chr20_-_29420713 2.18 ENSDART00000147464
ryanodine receptor 3
chr19_+_12762887 2.14 ENSDART00000139909
melanocortin 5a receptor
chr5_+_16117871 2.12 ENSDART00000090657
zinc and ring finger 3
chr22_-_14367966 2.12 ENSDART00000188796
low density lipoprotein receptor-related protein 1Ba
chr24_+_42148140 2.11 ENSDART00000010658
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr18_-_14941840 2.10 ENSDART00000091729
megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_-_72269049 2.10 ENSDART00000161497

chr1_+_157793 2.10 ENSDART00000152205
cullin 4A
chr5_-_33460959 2.09 ENSDART00000085636
si:ch211-182d3.1
chr9_+_54290896 2.09 ENSDART00000149175
POU class 4 homeobox 3
chr16_+_22345513 2.07 ENSDART00000078000
zgc:123238
chr3_-_18373425 2.06 ENSDART00000178522
sperm associated antigen 9a
chr24_-_17023392 2.05 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr5_-_69180587 2.03 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr2_+_53359234 2.03 ENSDART00000147581
cugbp, Elav-like family member 5b
chr17_-_38887424 2.03 ENSDART00000141177
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr21_+_5915041 2.01 ENSDART00000151370
proline dehydrogenase (oxidase) 1a
chr8_+_23916647 1.97 ENSDART00000143152
copine Va
chr1_+_40237276 1.96 ENSDART00000037553
fatty acid amide hydrolase 2a
chr14_+_31739568 1.95 ENSDART00000183507
adhesion G protein-coupled receptor G4a
chr22_-_16403602 1.95 ENSDART00000183417
laminin, alpha 3
chr22_+_39074688 1.92 ENSDART00000153547
inositol hexakisphosphate kinase 1
chr13_+_38814521 1.91 ENSDART00000110976
collagen, type XIX, alpha 1
chr14_-_14659023 1.90 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr16_-_32975951 1.89 ENSDART00000101969
ENSDART00000175149
malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_-_31376606 1.88 ENSDART00000098988
ENSDART00000125746
clusterin-like 1 (retinal)
chr23_+_45822935 1.88 ENSDART00000161892
vitamin D receptor a
chr14_+_45559268 1.86 ENSDART00000173152
zgc:154040
chr20_-_53435483 1.83 ENSDART00000135091
methyltransferase like 24
chr3_+_37827373 1.79 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr13_-_40120252 1.78 ENSDART00000157852
cartilage acidic protein 1b
chr18_+_50275933 1.76 ENSDART00000143911
si:dkey-105e17.1
chr20_+_42668875 1.75 ENSDART00000048890
solute carrier family 22 (organic cation transporter), member 2
chr15_-_33325019 1.75 ENSDART00000181092
ENSDART00000168920
neurobeachin b
chr15_-_36533322 1.73 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
chr5_-_46273938 1.73 ENSDART00000080033
si:ch211-130m23.3
chr23_-_30076950 1.71 ENSDART00000180139
calmodulin binding transcription activator 1a
chr9_+_51882534 1.71 ENSDART00000165493

chr18_-_6460102 1.70 ENSDART00000137037
IQ motif and Sec7 domain 3b
chr8_+_1651821 1.70 ENSDART00000060865
ENSDART00000186304
RAS protein activator like 1b (GAP1 like)
chr23_-_35347714 1.66 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr2_-_11512819 1.66 ENSDART00000142013
proenkephalin a
chr15_-_27710513 1.66 ENSDART00000005641
ENSDART00000134373
LIM homeobox 1a
chr14_+_33723309 1.65 ENSDART00000132488
apelin
chr12_+_21299338 1.64 ENSDART00000074540
ENSDART00000133188
carbonic anhydrase Xa
chr7_-_18168493 1.64 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr20_-_35052823 1.63 ENSDART00000153033
kinesin family member 26Bb
chr7_-_32598383 1.63 ENSDART00000111055
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_+_37824268 1.63 ENSDART00000137038
acid-sensing (proton-gated) ion channel 2
chr12_+_16106459 1.62 ENSDART00000114174
mucin 13b, cell surface associated
chr6_+_39836474 1.62 ENSDART00000112637
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr21_+_17768174 1.60 ENSDART00000141380
retinoid X receptor, alpha a
chr6_+_13024448 1.60 ENSDART00000104768
paroxysmal nonkinesigenic dyskinesia
chr6_-_40058686 1.59 ENSDART00000103240
urocanate hydratase 1
chr23_-_17509656 1.59 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr16_+_3982590 1.59 ENSDART00000149295
zinc finger CCCH-type containing 12A
chr5_-_69180227 1.57 ENSDART00000154816
zgc:171967
chr21_+_31838386 1.55 ENSDART00000135591
si:ch211-12m10.1
chr15_-_47929455 1.54 ENSDART00000064462
proteasome subunit alpha 6, like
chr15_-_47193564 1.53 ENSDART00000172453
limbic system-associated membrane protein
chr14_-_2221877 1.53 ENSDART00000106704
protocadherin 2 alpha b 1
chr6_-_20707846 1.52 ENSDART00000169836
collagen type XVIII alpha 1 chain b
chr15_+_21276735 1.51 ENSDART00000111213
ubiquitin associated and SH3 domain containing Bb
chr2_-_55337585 1.51 ENSDART00000177924
tropomyosin 4b
chr4_-_4119396 1.50 ENSDART00000067409
ENSDART00000138221
leiomodin 2 (cardiac) b
chr4_-_17263210 1.49 ENSDART00000147853
lymphoid-restricted membrane protein
chr23_+_45906137 1.49 ENSDART00000159939
ATP-binding cassette, sub-family G (WHITE), member 2a
chr10_-_43029001 1.48 ENSDART00000171494
single-stranded DNA binding protein 2
chr12_+_6214041 1.48 ENSDART00000179759
protein kinase, cGMP-dependent, type Ib
chr3_-_28750495 1.48 ENSDART00000054408
gsg1-like
chr23_+_21566828 1.47 ENSDART00000134741
ENSDART00000111966
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr17_-_15657029 1.46 ENSDART00000153925
fucosyltransferase 9a
chr22_+_7742211 1.46 ENSDART00000140896
zgc:92511
chr1_-_714626 1.46 ENSDART00000161072
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr6_-_25181012 1.44 ENSDART00000161585
leucine rich repeat containing 8 VRAC subunit Db
chr21_+_9628854 1.44 ENSDART00000161753
ENSDART00000160711
mitogen-activated protein kinase 10
chr24_-_20320480 1.42 ENSDART00000137366
mitogen-activated protein kinase kinase kinase 20
chr6_-_40744720 1.39 ENSDART00000154916
ENSDART00000186922
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr9_-_362971 1.39 ENSDART00000168944
si:dkey-11f4.7
chr13_+_51869025 1.39 ENSDART00000187066

chr6_+_4299164 1.38 ENSDART00000159759
neurobeachin-like 1
chr12_+_33396489 1.38 ENSDART00000149960
fatty acid synthase
chr14_-_31060082 1.36 ENSDART00000111601
ENSDART00000161113
muscleblind-like splicing regulator 3
chr17_-_25395395 1.35 ENSDART00000170233
family with sequence similarity 167, member B
chr8_+_8532407 1.35 ENSDART00000169276
ENSDART00000138993
glutamate receptor, metabotropic 6a
chr21_-_37790727 1.35 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr9_-_23217196 1.34 ENSDART00000083567
kinesin family member 5C
chr2_-_36925561 1.34 ENSDART00000187690
microtubule-associated protein 1Sb
chr5_+_31049742 1.33 ENSDART00000173097
zinc finger, ZZ-type with EF hand domain 1
chr17_-_29194219 1.32 ENSDART00000157340
spectrin, beta, non-erythrocytic 5
chr8_-_32497815 1.32 ENSDART00000122359
si:dkey-164f24.2
chr16_-_28709874 1.31 ENSDART00000127753
ADAM metallopeptidase domain 15
chr4_-_2867461 1.29 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr6_+_59967994 1.29 ENSDART00000050457
zgc:65895
chr12_-_10220036 1.29 ENSDART00000134619
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr12_-_36045283 1.28 ENSDART00000160646
G protein-coupled receptor, class C, group 5, member C
chr24_+_27268001 1.27 ENSDART00000122639
vasoactive intestinal peptide receptor 2
chr15_+_20548212 1.27 ENSDART00000193519
ENSDART00000169941
ENSDART00000187940
ENSDART00000183871
small G protein signaling modulator 2
chr14_+_8275115 1.26 ENSDART00000129055
neuregulin 2b
chr2_+_15776156 1.26 ENSDART00000190795
vav 3 guanine nucleotide exchange factor b
chr8_+_68864 1.26 ENSDART00000164574
proline rich 16
chr25_-_169291 1.25 ENSDART00000128344
lipase, hepatic b
chr17_-_31483469 1.24 ENSDART00000062907
ENSDART00000061547
leukocyte receptor tyrosine kinase
chr6_+_32497493 1.23 ENSDART00000184819
KN motif and ankyrin repeat domains 4
chr24_+_42149453 1.21 ENSDART00000128766
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr18_+_9810642 1.21 ENSDART00000143965
si:dkey-266j7.2
chr19_+_8612839 1.20 ENSDART00000144925
sorting nexin family member 27a
chr17_-_20430177 1.20 ENSDART00000114236
sortilin related VPS10 domain containing receptor 3b
chr16_-_20707742 1.20 ENSDART00000103630
cAMP responsive element binding protein 5b
chr9_+_34434943 1.19 ENSDART00000175455
si:ch211-269e2.1
chr17_-_3291369 1.19 ENSDART00000181840

chr10_-_41352502 1.19 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr10_+_32646402 1.18 ENSDART00000137244
zinc finger and BTB domain containing 21
chr2_+_20331445 1.18 ENSDART00000186880
phospholipid phosphatase related 4a
chr22_-_20376488 1.18 ENSDART00000140187
zinc finger and BTB domain containing 7a
chr21_+_5993188 1.16 ENSDART00000048399
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr23_+_26039524 1.16 ENSDART00000142851
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr11_+_11175814 1.16 ENSDART00000183864

chr20_-_32112818 1.13 ENSDART00000142653
glutamate receptor, metabotropic 1a
chr12_+_49114483 1.13 ENSDART00000181696

chr1_-_58975098 1.11 ENSDART00000189899

chr17_-_28749640 1.11 ENSDART00000000948
coagulation factor C homolog, cochlin (Limulus polyphemus)
chr6_+_58406014 1.11 ENSDART00000044241
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr3_-_22829710 1.10 ENSDART00000055659
cytochrome b561
chr16_-_31756859 1.10 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
protein tyrosine phosphatase, non-receptor type 6
chr16_+_29586468 1.10 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr9_-_30363770 1.09 ENSDART00000147030
synaptotagmin-like 5
chr1_-_17735861 1.08 ENSDART00000018238
PDZ and LIM domain 3a
chr7_-_35379899 1.08 ENSDART00000183484
solute carrier family 6 (neurotransmitter transporter), member 2
chr7_+_18100996 1.07 ENSDART00000055810
zRAB1B, member RAS oncogene family a
chr17_-_13070602 1.05 ENSDART00000188311
ENSDART00000193428

chr7_+_33279108 1.04 ENSDART00000084530
coronin, actin binding protein, 2Ba
chr4_+_14717502 1.04 ENSDART00000067031
potassium inwardly-rectifying channel, subfamily J, member 8
chr17_+_1323699 1.03 ENSDART00000172540
adenylosuccinate synthase like 1
chr11_+_30161699 1.03 ENSDART00000190504
cyclin-dependent kinase-like 5
chr23_+_14269311 1.02 ENSDART00000170414

chr11_+_30162407 1.02 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr4_+_45484774 1.02 ENSDART00000150573
si:dkey-256i11.6
chr17_+_10748366 1.01 ENSDART00000018683
ENSDART00000097274
zgc:113944
chr1_-_45889820 1.01 ENSDART00000144735
patatin-like phospholipase domain containing 6
chr13_+_31144305 0.99 ENSDART00000189602

chr7_+_25858380 0.98 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr19_+_58954 0.97 ENSDART00000162379
collagen, type XIV, alpha 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of hmx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
1.0 3.0 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.8 2.4 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.7 2.0 GO:0015874 norepinephrine transport(GO:0015874)
0.6 1.9 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.6 1.8 GO:0015695 organic cation transport(GO:0015695)
0.6 1.7 GO:0097376 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.5 1.6 GO:0006089 lactate metabolic process(GO:0006089)
0.5 2.7 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.5 2.1 GO:0032801 receptor catabolic process(GO:0032801)
0.5 4.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.5 1.5 GO:0035046 pronuclear migration(GO:0035046)
0.5 3.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.4 5.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 2.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.4 4.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.4 2.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.3 1.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 3.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 2.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 2.6 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.2 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.2 4.8 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.2 2.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.6 GO:0036076 ligamentous ossification(GO:0036076)
0.2 0.6 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 1.3 GO:0099640 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.2 2.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.2 1.9 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.2 1.2 GO:0070285 pigment cell development(GO:0070285)
0.2 9.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 5.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 3.6 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 1.0 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 1.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 3.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.5 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.5 GO:0043476 pigment accumulation(GO:0043476)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 3.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.5 GO:0036065 fucosylation(GO:0036065)
0.1 2.5 GO:0006828 manganese ion transport(GO:0006828)
0.1 2.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.2 GO:0006829 zinc II ion transport(GO:0006829)
0.1 9.8 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.2 GO:0015871 choline transport(GO:0015871)
0.1 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 2.4 GO:0072348 sulfur compound transport(GO:0072348)
0.1 4.5 GO:0071482 cellular response to light stimulus(GO:0071482)
0.1 0.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 2.8 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 0.8 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 4.6 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 1.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 1.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 1.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.6 GO:0032526 response to retinoic acid(GO:0032526)
0.1 1.9 GO:0001878 response to yeast(GO:0001878)
0.0 2.2 GO:0007586 digestion(GO:0007586)
0.0 0.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 2.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.8 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0033273 response to vitamin(GO:0033273)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 2.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.4 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 2.4 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 1.0 GO:1990573 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.0 2.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.2 GO:0045055 regulated exocytosis(GO:0045055)
0.0 3.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 3.0 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 1.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.1 GO:0007605 sensory perception of sound(GO:0007605)
0.0 3.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.3 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 2.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 6.0 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 3.1 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.8 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 1.4 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.1 GO:0022900 electron transport chain(GO:0022900)
0.0 5.0 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 2.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 2.8 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0006497 protein lipidation(GO:0006497)
0.0 0.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 1.8 GO:0048793 pronephros development(GO:0048793)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.7 2.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.5 1.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.4 2.6 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.4 5.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 2.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 0.6 GO:0010369 chromocenter(GO:0010369)
0.2 1.3 GO:0070062 extracellular exosome(GO:0070062)
0.2 4.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 2.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 1.1 GO:0043194 axon initial segment(GO:0043194)
0.1 2.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.1 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 5.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.4 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 3.0 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0008278 cohesin complex(GO:0008278)
0.0 2.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.3 GO:0005604 basement membrane(GO:0005604)
0.0 4.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.3 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 3.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 3.5 GO:0034703 cation channel complex(GO:0034703)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0036126 sperm flagellum(GO:0036126)
0.0 5.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.7 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 3.8 GO:0045202 synapse(GO:0045202)
0.0 1.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.0 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 5.0 GO:0043005 neuron projection(GO:0043005)
0.0 12.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.5 GO:0032052 bile acid binding(GO:0032052)
1.2 5.8 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.7 2.1 GO:0031704 apelin receptor binding(GO:0031704)
0.7 2.0 GO:0005330 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.6 3.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.5 2.7 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.5 2.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.5 1.9 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 3.9 GO:0004359 glutaminase activity(GO:0004359)
0.4 1.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.4 2.1 GO:0008432 JUN kinase binding(GO:0008432)
0.4 1.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.4 1.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 5.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.4 2.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 3.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 2.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.2 2.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 2.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 1.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 1.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.6 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 1.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 5.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.4 GO:0031628 opioid receptor binding(GO:0031628)
0.2 1.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 3.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 1.1 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 4.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.6 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.1 1.8 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 1.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 6.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.5 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.5 GO:0050699 WW domain binding(GO:0050699)
0.1 9.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 2.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.3 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 6.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 2.6 GO:0042562 hormone binding(GO:0042562)
0.0 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.3 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 14.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 4.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 4.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 3.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 3.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 9.2 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 4.2 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 1.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.3 4.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 1.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 3.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 4.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 4.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 2.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization