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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hmga1a

Z-value: 0.70

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Transcription factors associated with hmga1a

Gene Symbol Gene ID Gene Info
hmga1a
ENSDARG00000028335 high mobility group AT-hook 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmga1adr11_v1_chr23_-_3759692_37596920.961.6e-10Click!

Activity profile of hmga1a motif

Sorted Z-values of hmga1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_20195350 3.31 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr7_-_64971839 2.02 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr16_+_1383914 1.96 ENSDART00000185089
cers2b
ceramide synthase 2b
chr14_-_38827442 1.80 ENSDART00000160000
spdl1
spindle apparatus coiled-coil protein 1
chr14_-_38828057 1.46 ENSDART00000186088
spdl1
spindle apparatus coiled-coil protein 1
chr19_+_29808699 1.33 ENSDART00000051799
ENSDART00000164205
hdac1
histone deacetylase 1
chr1_+_47335038 1.18 ENSDART00000188153
bcl9
B cell CLL/lymphoma 9
chr13_+_41917606 1.16 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr7_+_33130639 1.12 ENSDART00000142450
ENSDART00000173967
ENSDART00000173832
zgc:153219
si:ch211-194p6.7
zgc:153219
si:ch211-194p6.7
chr5_+_32831561 1.10 ENSDART00000169358
ENSDART00000192078
si:ch211-208h16.4
si:ch211-208h16.4
chr19_+_29808471 1.07 ENSDART00000186428
hdac1
histone deacetylase 1
chr18_-_35407289 1.05 ENSDART00000012018
snrpa
small nuclear ribonucleoprotein polypeptide A
chr17_-_40110782 1.04 ENSDART00000126929
si:dkey-187k19.2
si:dkey-187k19.2
chr24_-_15159658 1.01 ENSDART00000142473
rttn
rotatin
chr24_-_31090948 0.99 ENSDART00000176799
hccsb
holocytochrome c synthase b
chr18_+_328689 0.94 ENSDART00000167841
ss18l2
synovial sarcoma translocation gene on chromosome 18-like 2
chr2_+_25839193 0.93 ENSDART00000078634
eif5a2
eukaryotic translation initiation factor 5A2
chr20_+_35255403 0.90 ENSDART00000002773
ENSDART00000137915
fam49a
family with sequence similarity 49, member A
chr1_-_54972170 0.88 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr6_-_39518489 0.87 ENSDART00000185446
atf1
activating transcription factor 1
chr7_-_33130552 0.86 ENSDART00000127006
mns1
meiosis-specific nuclear structural 1
chr10_+_20364009 0.84 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr6_-_58764672 0.81 ENSDART00000154322
soat2
sterol O-acyltransferase 2
chr2_+_32846602 0.80 ENSDART00000056649
tmem53
transmembrane protein 53
chr3_-_34136368 0.80 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr5_-_39805874 0.79 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr6_-_58757131 0.78 ENSDART00000083582
soat2
sterol O-acyltransferase 2
chr14_-_34513103 0.78 ENSDART00000136306
zgc:194246
zgc:194246
chr19_-_20403507 0.77 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr22_-_784110 0.76 ENSDART00000061775
rbbp5
retinoblastoma binding protein 5
chr16_-_42969598 0.75 ENSDART00000156011
si:ch211-135n15.3
si:ch211-135n15.3
chr9_+_25568839 0.73 ENSDART00000177342
zeb2a
zinc finger E-box binding homeobox 2a
chr18_-_35407695 0.72 ENSDART00000191845
ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr18_-_35407530 0.72 ENSDART00000137663
snrpa
small nuclear ribonucleoprotein polypeptide A
chr6_-_2222707 0.69 ENSDART00000022179
prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr9_-_27738110 0.69 ENSDART00000060347
crygs2
crystallin, gamma S2
chr25_-_13789955 0.69 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
ckap5
cytoskeleton associated protein 5
chr4_-_4535189 0.67 ENSDART00000057519
zgc:194209
zgc:194209
chr6_+_30533504 0.65 ENSDART00000155842
wwc3
WWC family member 3
chr1_-_54971968 0.65 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr23_-_28347039 0.65 ENSDART00000145072
neurod4
neuronal differentiation 4
chr24_-_35534273 0.64 ENSDART00000026578
ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr15_-_33807758 0.62 ENSDART00000158445
pds5b
PDS5 cohesin associated factor B
chr9_-_12885201 0.62 ENSDART00000124957
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr9_-_2892250 0.61 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr1_+_31658011 0.61 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr3_+_62161184 0.59 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr23_+_25354856 0.58 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3
chr23_+_38940700 0.58 ENSDART00000065331
sall4
spalt-like transcription factor 4
chr7_+_15871156 0.57 ENSDART00000145946
pax6b
paired box 6b
chr15_+_888704 0.54 ENSDART00000182796
si:dkey-7i4.9
si:dkey-7i4.9
chr15_+_47440477 0.54 ENSDART00000002384
phox2a
paired-like homeobox 2a
chr4_+_13568469 0.51 ENSDART00000171235
ENSDART00000136152
calua
calumenin a
chr23_-_45407631 0.51 ENSDART00000148484
ENSDART00000150186
zgc:101853
zgc:101853
chr10_+_42733210 0.48 ENSDART00000189832
CABZ01063556.1

chr14_+_26566936 0.48 ENSDART00000173056
arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr8_-_50981175 0.48 ENSDART00000004065
zgc:91909
zgc:91909
chr15_-_29387446 0.48 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr25_-_34670413 0.47 ENSDART00000073440
DNAJA4
DnaJ heat shock protein family (Hsp40) member A4
chr7_-_22956889 0.45 ENSDART00000101447
tnfsf10l
TNF superfamily member 10, like
chr6_-_7123210 0.44 ENSDART00000041304
atg3
autophagy related 3
chr13_-_41917050 0.42 ENSDART00000110549
cisd1
CDGSH iron sulfur domain 1
chr21_+_21743599 0.41 ENSDART00000101700
pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr7_+_19615056 0.40 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr6_+_28294113 0.38 ENSDART00000136898
lpp
LIM domain containing preferred translocation partner in lipoma
chr7_-_22956716 0.38 ENSDART00000122113
tnfsf10l
TNF superfamily member 10, like
chr16_-_29557338 0.38 ENSDART00000058888
hormad1
HORMA domain containing 1
chr12_+_33919502 0.37 ENSDART00000085888
trim8b
tripartite motif containing 8b
chr5_-_20814576 0.37 ENSDART00000098682
ENSDART00000147639
si:ch211-225b11.1
si:ch211-225b11.1
chr19_-_3741602 0.36 ENSDART00000170301
btr22
bloodthirsty-related gene family, member 22
chr6_+_22679610 0.35 ENSDART00000102701
zmp:0000000634
zmp:0000000634
chr10_+_6121558 0.34 ENSDART00000166799
ENSDART00000157947
tln1
talin 1
chr20_+_26349002 0.34 ENSDART00000152842
syne1a
spectrin repeat containing, nuclear envelope 1a
chr14_-_15699528 0.33 ENSDART00000161123
neurl1b
neuralized E3 ubiquitin protein ligase 1B
chr15_+_17030941 0.33 ENSDART00000062069
plin2
perilipin 2
chr25_+_19739665 0.32 ENSDART00000067353
zgc:101783
zgc:101783
chr5_+_41476443 0.31 ENSDART00000145228
ENSDART00000137981
ENSDART00000142538
pias2
protein inhibitor of activated STAT, 2
chr14_-_33521071 0.31 ENSDART00000052789
c1galt1c1
C1GALT1-specific chaperone 1
chr20_+_34400715 0.30 ENSDART00000061632
fam129aa
family with sequence similarity 129, member Aa
chr15_+_17030473 0.29 ENSDART00000129407
plin2
perilipin 2
chr5_-_38451082 0.29 ENSDART00000136428
chrne
cholinergic receptor, nicotinic, epsilon
chr9_-_41507712 0.29 ENSDART00000135821
mfsd6b
major facilitator superfamily domain containing 6b
chr12_-_10409961 0.28 ENSDART00000149521
ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr25_+_15287036 0.27 ENSDART00000147572
hipk3a
homeodomain interacting protein kinase 3a
chr12_+_46386983 0.26 ENSDART00000183982
BX005305.3
Danio rerio legumain (LOC100005356), mRNA.
chr25_-_2355107 0.26 ENSDART00000056121
mrps35
mitochondrial ribosomal protein S35
chr12_+_46425800 0.26 ENSDART00000191965
BX005305.1

chr4_+_17245005 0.24 ENSDART00000027645
casc1
cancer susceptibility candidate 1
chr16_-_26232411 0.23 ENSDART00000139355
arhgef1b
Rho guanine nucleotide exchange factor (GEF) 1b
chr4_+_17245217 0.23 ENSDART00000184215
ENSDART00000110908
casc1
cancer susceptibility candidate 1
chr12_+_46404307 0.23 ENSDART00000185011
BX005305.4

chr25_-_17910714 0.21 ENSDART00000191586
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr12_+_46512881 0.21 ENSDART00000105454
CU855711.1

chr10_-_26202766 0.20 ENSDART00000136393
fhdc3
FH2 domain containing 3
chr24_-_16975960 0.20 ENSDART00000180687
klhl15
kelch-like family member 15
chr5_-_1203455 0.20 ENSDART00000172177
surf4
surfeit gene 4
chr12_+_46443477 0.20 ENSDART00000191873
BX005305.1

chr8_-_49725430 0.18 ENSDART00000135675
gkap1
G kinase anchoring protein 1
chr17_-_21200406 0.18 ENSDART00000104708
abhd12
abhydrolase domain containing 12
chr18_+_14595546 0.18 ENSDART00000080788
wfdc1
WAP four-disulfide core domain 1
chr11_+_5817202 0.16 ENSDART00000126084
ctdspl3
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr10_-_22106331 0.16 ENSDART00000187654
BX005027.2

chr13_+_49175624 0.16 ENSDART00000193550
egln1a
egl-9 family hypoxia-inducible factor 1a
chr3_+_57820913 0.15 ENSDART00000168101
CU571328.1

chr12_+_46483618 0.15 ENSDART00000186970
BX005305.5

chr21_-_588858 0.14 ENSDART00000168983
TMEM38B
transmembrane protein 38B
chr14_+_34951202 0.14 ENSDART00000047524
ENSDART00000115105
il12ba
interleukin 12Ba
chr5_+_71924175 0.14 ENSDART00000115182
ENSDART00000170215
nup214
nucleoporin 214
chr12_+_46462090 0.13 ENSDART00000130748
BX005305.2

chr17_+_31739418 0.13 ENSDART00000155073
ENSDART00000156180
arhgap5
Rho GTPase activating protein 5
chr6_+_8630355 0.12 ENSDART00000161749
ENSDART00000193976
tspeara
thrombospondin-type laminin G domain and EAR repeats a
chr15_-_37436082 0.11 ENSDART00000192423
si:ch211-113j13.2
si:ch211-113j13.2
chr17_-_5769196 0.11 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr4_+_26053044 0.11 ENSDART00000039877
SCYL2
si:ch211-244b2.1
chr4_-_45028479 0.10 ENSDART00000143150
ENSDART00000076870
si:dkey-51d8.1
si:dkey-51d8.1
chr1_+_49814461 0.09 ENSDART00000132405
lef1
lymphoid enhancer-binding factor 1
chr11_+_36683859 0.09 ENSDART00000170102
si:ch211-11c3.12
si:ch211-11c3.12
chr12_+_4686145 0.08 ENSDART00000128145
kansl1a
KAT8 regulatory NSL complex subunit 1a
chr10_-_40617534 0.08 ENSDART00000148070
ENSDART00000131599
taar16g
trace amine associated receptor 16g
chr20_-_874807 0.07 ENSDART00000020506
snx14
sorting nexin 14
chr16_-_12236362 0.07 ENSDART00000114759
lpcat3
lysophosphatidylcholine acyltransferase 3
chr13_+_49175947 0.07 ENSDART00000056927
egln1a
egl-9 family hypoxia-inducible factor 1a
chr4_+_19127973 0.07 ENSDART00000136611
si:dkey-21o22.2
si:dkey-21o22.2
chr18_+_14595805 0.04 ENSDART00000167825
wfdc1
WAP four-disulfide core domain 1
chr25_-_13549577 0.03 ENSDART00000166772
ano10b
anoctamin 10b
chr15_+_15856178 0.03 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr20_-_46249185 0.03 ENSDART00000100544
taar10
trace amine-associated receptor 10
chr21_+_40302747 0.02 ENSDART00000174166
si:ch211-218m3.18
si:ch211-218m3.18

Network of associatons between targets according to the STRING database.

First level regulatory network of hmga1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.4 3.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 2.4 GO:0033687 osteoblast proliferation(GO:0033687)
0.2 1.0 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 1.6 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.2 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.9 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 0.9 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 1.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.8 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.7 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.6 GO:0001839 neural plate morphogenesis(GO:0001839)
0.1 0.8 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.6 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.3 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.5 GO:0021703 locus ceruleus development(GO:0021703)
0.0 0.8 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.9 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.2 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.8 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.6 GO:0006301 postreplication repair(GO:0006301)
0.0 1.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.6 GO:0048538 thymus development(GO:0048538)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0031514 motile cilium(GO:0031514)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.4 1.6 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.4 3.3 GO:0043515 kinetochore binding(GO:0043515)
0.3 2.5 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.0 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 2.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 1.5 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 2.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.8 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.7 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 1.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0016208 AMP binding(GO:0016208)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS