Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4

Z-value: 0.51

Motif logo

logo of logo of

Transcription factors associated with her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4

Gene Symbol Gene ID Gene Info
her11
ENSDARG00000002707 hairy-related 11
her5
ENSDARG00000008796 hairy-related 5
her1
ENSDARG00000014722 hairy-related 1
her4.4
ENSDARG00000009822 hairy-related 4, tandem duplicate 4
her12
ENSDARG00000032963 hairy-related 12
her2
ENSDARG00000038205 hairy-related 2
her15.2
ENSDARG00000054560 hairy and enhancer of split-related 15, tandem duplicate 2
her15.1
ENSDARG00000054562 hairy and enhancer of split-related 15, tandem duplicate 1
her4.2
ENSDARG00000056729 hairy-related 4, tandem duplicate 2
her4.1
ENSDARG00000056732 hairy-related 4, tandem duplicate 1
her4.3
ENSDARG00000070770 hairy-related 4, tandem duplicate 3
her4.2
ENSDARG00000094426 hairy-related 4, tandem duplicate 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
her1dr11_v1_chr5_-_68795063_68795063-0.821.7e-05Click!
her5dr11_v1_chr14_+_30543008_30543008-0.671.6e-03Click!
her11dr11_v1_chr14_-_30540967_30540967-0.483.7e-02Click!
her4.1dr11_v1_chr23_-_21453614_214536140.455.2e-02Click!
her2dr11_v1_chr11_-_41966854_41966854-0.399.9e-02Click!
her4.2dr11_v1_chr23_+_21455152_214551540.351.5e-01Click!
her4.3dr11_v1_chr23_+_21459263_214592630.302.1e-01Click!
her4.4dr11_v1_chr23_-_21463788_214637880.302.1e-01Click!
her15.2dr11_v1_chr11_-_41996957_419969570.213.9e-01Click!
her15.1dr11_v1_chr11_+_41981959_419819590.087.3e-01Click!
her12dr11_v1_chr23_-_21446985_21446985-0.068.2e-01Click!

Activity profile of her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4 motif

Sorted Z-values of her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_31183495 2.27 ENSDART00000088618
meox2b
mesenchyme homeobox 2b
chr16_-_45069882 2.01 ENSDART00000058384
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr14_+_46313135 1.99 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr6_-_60147517 1.79 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr6_+_39184236 1.04 ENSDART00000156187
tac3b
tachykinin 3b
chr9_-_44295071 1.00 ENSDART00000011837
neurod1
neuronal differentiation 1
chr14_+_46313396 0.86 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr23_+_21459263 0.67 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr23_-_21463788 0.64 ENSDART00000079265
her4.4
hairy-related 4, tandem duplicate 4
chr20_-_27733683 0.50 ENSDART00000103317
ENSDART00000138139
zgc:153157
zgc:153157
chr8_+_21146262 0.50 ENSDART00000045684
porcn
porcupine O-acyltransferase
chr19_+_42470396 0.42 ENSDART00000191679
si:dkey-166k12.1
si:dkey-166k12.1
chr19_+_42469058 0.32 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr3_+_23029934 0.28 ENSDART00000110343
nags
N-acetylglutamate synthase
chr5_-_45894802 0.27 ENSDART00000097648
crfb6
cytokine receptor family member b6
chr10_-_27566481 0.26 ENSDART00000078920
auts2a
autism susceptibility candidate 2a
chr11_-_3959889 0.26 ENSDART00000159683
pbrm1
polybromo 1
chr23_-_31969786 0.23 ENSDART00000134550
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr10_+_158590 0.23 ENSDART00000081982
KCNJ15
potassium voltage-gated channel subfamily J member 15
chr7_+_32021669 0.21 ENSDART00000173976
mettl15
methyltransferase like 15
chr11_-_3959477 0.20 ENSDART00000045971
pbrm1
polybromo 1
chr18_+_6126506 0.19 ENSDART00000125725
si:ch1073-390k14.1
si:ch1073-390k14.1
chr8_+_39760258 0.17 ENSDART00000037914
cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr12_+_33038757 0.16 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr5_-_46329880 0.15 ENSDART00000156577
si:ch211-130m23.5
si:ch211-130m23.5
chr7_+_32021982 0.14 ENSDART00000173848
mettl15
methyltransferase like 15
chr2_-_32386791 0.12 ENSDART00000056634
ubtfl
upstream binding transcription factor, like
chr9_+_45789887 0.11 ENSDART00000135202
si:dkey-34f9.3
si:dkey-34f9.3
chr10_+_17026870 0.10 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr18_+_30370559 0.10 ENSDART00000165450
gse1
Gse1 coiled-coil protein
chr21_-_38730557 0.09 ENSDART00000150984
ENSDART00000111885
taf9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr18_+_30370339 0.09 ENSDART00000158871
gse1
Gse1 coiled-coil protein
chr3_+_32425202 0.09 ENSDART00000156464
prr12b
proline rich 12b
chr3_-_6441619 0.08 ENSDART00000157771
ENSDART00000166758
sumo2b
small ubiquitin-like modifier 2b
chr24_+_31459715 0.07 ENSDART00000181102
ENSDART00000189950
ENSDART00000192321
ENSDART00000126380
cnbd1
cyclic nucleotide binding domain containing 1
chr19_-_35596207 0.07 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr20_+_19212962 0.07 ENSDART00000063706
fndc4a
fibronectin type III domain containing 4a
chr19_+_42142381 0.04 ENSDART00000129915
kcnq4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr25_-_37284370 0.03 ENSDART00000103222
nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr16_-_4026265 0.00 ENSDART00000149339
si:ch211-175f12.2
si:ch211-175f12.2

Network of associatons between targets according to the STRING database.

First level regulatory network of her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.5 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.2 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.8 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 2.0 GO:0006096 glycolytic process(GO:0006096)
0.0 2.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 2.3 GO:0061053 somite development(GO:0061053)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.5 GO:0016586 RSC complex(GO:0016586)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.8 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.0 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits