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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gsc

Z-value: 1.48

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Transcription factors associated with gsc

Gene Symbol Gene ID Gene Info
ENSDARG00000059073 goosecoid
ENSDARG00000111184 goosecoid
ENSDARG00000115937 goosecoid

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gscdr11_v1_chr17_-_19344999_193449990.716.7e-04Click!

Activity profile of gsc motif

Sorted Z-values of gsc motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_54077740 14.28 ENSDART00000027000
rhodopsin
chr17_-_51202339 8.70 ENSDART00000167117
si:ch1073-469d17.2
chr14_+_32838110 7.37 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr6_+_41186320 7.24 ENSDART00000025241
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr6_-_345503 6.48 ENSDART00000168901
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr11_-_15090118 6.25 ENSDART00000171118
solute carrier family 1 (glutamate transporter), member 8a
chr3_-_32170850 6.15 ENSDART00000055307
ENSDART00000157366
troponin T type 1 (skeletal, slow)
chr11_-_15090564 5.55 ENSDART00000162079
solute carrier family 1 (glutamate transporter), member 8a
chr14_+_32839535 5.22 ENSDART00000168975
arrestin 3b, retinal (X-arrestin)
chr15_+_45640906 5.10 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr19_+_40856534 5.07 ENSDART00000051950
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr14_+_32837914 5.05 ENSDART00000158888
arrestin 3b, retinal (X-arrestin)
chr7_-_13882988 4.76 ENSDART00000169828
retinaldehyde binding protein 1a
chr10_-_20453995 4.62 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
chr19_+_40856807 4.60 ENSDART00000139083
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr14_+_46313396 4.46 ENSDART00000047525
crystallin, beta A1, like 1
chr5_+_28973264 4.28 ENSDART00000005638
syntaxin binding protein 1b
chr1_-_58009216 4.14 ENSDART00000143829
nucleoredoxin like 1
chr5_+_28972935 4.12 ENSDART00000193274
syntaxin binding protein 1b
chr23_+_39854566 3.99 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr2_+_7192966 3.90 ENSDART00000142735
si:ch211-13f8.1
chr14_+_46313135 3.86 ENSDART00000172902
crystallin, beta A1, like 1
chr22_+_34701848 3.83 ENSDART00000082066
ATPase H+ transporting V0 subunit e2
chr5_-_38161033 3.54 ENSDART00000145907
guanylate cyclase 2D, retinal
chr6_+_48618512 3.49 ENSDART00000111190
si:dkey-238f9.1
chr3_-_28828242 3.41 ENSDART00000151445
si:ch211-76l23.4
chr17_-_16965809 3.34 ENSDART00000153697
neurexin 3a
chr14_-_36378494 3.12 ENSDART00000058503
glycoprotein M6Aa
chr17_+_36627099 2.99 ENSDART00000154104
interphotoreceptor matrix proteoglycan 1b
chr10_-_22845485 2.92 ENSDART00000079454
vesicle-associated membrane protein 2
chr21_-_28235361 2.90 ENSDART00000164458
neurexin 2a
chr13_+_29462249 2.87 ENSDART00000147903
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr7_+_56615554 2.77 ENSDART00000098430
dipeptidase 1
chr2_-_5356686 2.75 ENSDART00000124290
mitofusin 1
chr12_+_5530247 2.67 ENSDART00000114637
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr10_-_22249444 2.64 ENSDART00000148831
fibroblast growth factor 11b
chr9_+_33357011 2.57 ENSDART00000088569
nyctalopin
chr23_+_6232895 2.57 ENSDART00000139795
synaptotagmin IIa
chr2_-_4797512 2.56 ENSDART00000160765
tyrosine kinase, non-receptor, 2b
chr16_+_32059785 2.53 ENSDART00000134459
si:dkey-40m6.8
chr13_+_3954715 2.50 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
leucine rich repeat containing 73
chr8_+_23142946 2.50 ENSDART00000152933
si:ch211-196c10.13
chr3_+_34919810 2.50 ENSDART00000055264
carbonic anhydrase Xb
chr13_+_3954540 2.50 ENSDART00000092646
leucine rich repeat containing 73
chr5_+_1278092 2.48 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr7_-_49594995 2.40 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr15_+_9053059 2.40 ENSDART00000012039
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr23_-_21797517 2.40 ENSDART00000110041
leucine rich repeat containing 38a
chr13_+_12528043 2.38 ENSDART00000057761
retinal pigment epithelium-derived rhodopsin homolog
chr16_-_17188294 2.37 ENSDART00000165883
opsin 9
chr17_-_15149192 2.35 ENSDART00000180511
ENSDART00000103405
GTP cyclohydrolase 1
chr2_+_24199073 2.34 ENSDART00000144110
microtubule associated protein 4 like
chr2_-_30784198 2.34 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr22_+_5103349 2.34 ENSDART00000083474
ataxia, cerebellar, Cayman type a
chr25_+_27923846 2.32 ENSDART00000047007
solute carrier family 13 member 1
chr19_+_1097393 2.28 ENSDART00000168218

chr1_+_41690402 2.22 ENSDART00000177298
F-box protein 41
chr19_-_10373630 2.21 ENSDART00000131517
si:ch211-232m10.6
chr9_+_13685921 2.18 ENSDART00000145775
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr1_-_45920632 2.14 ENSDART00000140890
patatin-like phospholipase domain containing 6
chr24_-_6501211 2.14 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
G protein-coupled receptor 158a
chr11_-_44873780 2.10 ENSDART00000160465
opsin 6, group member a
chr3_+_34220194 2.08 ENSDART00000145859
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr6_+_9867426 2.05 ENSDART00000151749
si:ch211-222n4.6
chr25_-_17552299 2.01 ENSDART00000154327
si:dkey-44k1.5
chr23_-_10137322 1.97 ENSDART00000142442
plexin b1a
chr23_-_1587955 1.93 ENSDART00000136037
fibronectin type III domain containing 7b
chr7_-_66864756 1.87 ENSDART00000184462
ENSDART00000189424
adenosine monophosphate deaminase 3a
chr6_-_35401282 1.87 ENSDART00000127612
regulator of G protein signaling 5a
chr17_+_15845765 1.80 ENSDART00000130881
ENSDART00000074936
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr17_-_20979077 1.75 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr3_-_49504023 1.72 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr12_+_41991635 1.69 ENSDART00000186161
ENSDART00000192510
transcription elongation regulator 1 like
chr20_+_29587995 1.67 ENSDART00000153339
ADAM metallopeptidase domain 17b
chr25_+_192116 1.66 ENSDART00000153983
zgc:114188
chr12_+_47044707 1.65 ENSDART00000186506
zinc finger, RAN-binding domain containing 1a
chr20_-_25436389 1.62 ENSDART00000153266
intersectin 2a
chr1_-_45177373 1.60 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr22_+_38164486 1.57 ENSDART00000137521
transmembrane 4 L six family member 18
chr20_-_18736281 1.51 ENSDART00000142837
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr17_-_33414781 1.49 ENSDART00000142203
ENSDART00000034638
coiled-coil domain containing 28A
chr23_-_17509656 1.47 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr24_-_7777389 1.45 ENSDART00000138541
RPGR interacting protein 1
chr1_-_7894255 1.45 ENSDART00000167126
ENSDART00000145460
Ras association and DIL domains
chr20_-_14680897 1.43 ENSDART00000063857
ENSDART00000161314
secernin 2
chr3_+_26144765 1.43 ENSDART00000146267
ENSDART00000043932
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr2_+_28995776 1.43 ENSDART00000138733
cadherin 12, type 2a (N-cadherin 2)
chr24_-_24271629 1.40 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr3_-_16227683 1.35 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr4_-_14926637 1.35 ENSDART00000110199
PR domain containing 4
chr3_+_14157090 1.34 ENSDART00000156766
si:ch211-108d22.2
chr11_-_28148033 1.32 ENSDART00000177182
lactamase, beta-like 1b
chr6_-_59381391 1.30 ENSDART00000157066
protein phosphatase 1, regulatory subunit 16B
chr8_+_4337312 1.30 ENSDART00000182228
myosin, light chain 2b, regulatory, cardiac, slow
chr7_-_57933736 1.30 ENSDART00000142580
ankyrin 2b, neuronal
chr17_-_15657029 1.30 ENSDART00000153925
fucosyltransferase 9a
chr22_-_910926 1.29 ENSDART00000180075

chr24_-_38079261 1.28 ENSDART00000105662
C-reactive protein 1
chr15_+_15375607 1.27 ENSDART00000129751
si:ch211-105f12.2
chr10_+_22134606 1.26 ENSDART00000155228
si:dkey-4c2.11
chr2_-_1569250 1.25 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr7_-_9674073 1.22 ENSDART00000187902
leucine-rich repeat kinase 1
chr18_-_36135799 1.21 ENSDART00000059344
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr10_+_6013076 1.18 ENSDART00000167613
ENSDART00000159216
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr21_-_15046065 1.18 ENSDART00000178507
matrix metallopeptidase 17a
chr1_+_55758257 1.13 ENSDART00000139312
trans-2,3-enoyl-CoA reductase b
chr18_-_1228688 1.13 ENSDART00000064403
neuroplastin b
chr11_+_36180349 1.13 ENSDART00000012940
glutamate receptor, metabotropic 2b
chr7_-_35516251 1.12 ENSDART00000045628
iroquois homeobox 6a
chr2_+_30721070 1.08 ENSDART00000099052
si:dkey-94e7.2
chr22_+_38581012 1.06 ENSDART00000169239

chr24_-_24060632 1.06 ENSDART00000090514
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr20_-_9963713 1.04 ENSDART00000104234
gap junction protein delta 2b
chr21_-_2348838 1.03 ENSDART00000160337
si:ch73-299h12.8
chr19_+_24068223 1.00 ENSDART00000141351
ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr25_+_22274642 1.00 ENSDART00000127099
nuclear receptor subfamily 2, group E, member 3
chr9_-_29544720 1.00 ENSDART00000130317
Rho GTPase activating protein 20
chr18_-_43884044 1.00 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr10_-_36738619 0.99 ENSDART00000093000
ENSDART00000157179
si:ch211-176g13.7
chr2_-_52365251 0.98 ENSDART00000097716
transducin like enhancer of split 2c
chr2_+_30878864 0.98 ENSDART00000009326
opioid receptor, kappa 1
chr19_-_11846958 0.96 ENSDART00000148516
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr17_-_21368775 0.96 ENSDART00000058027
shootin 1
chr21_-_39327223 0.95 ENSDART00000115097
apoptosis-inducing factor, mitochondrion-associated, 5
chr4_-_7212875 0.94 ENSDART00000161297
leucine rich repeat neuronal 3b
chr15_-_38154616 0.91 ENSDART00000099392
immunity-related GTPase family, q2
chr16_-_22585289 0.87 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cingulin a
chr12_+_7865470 0.86 ENSDART00000161683

chr18_-_7948188 0.85 ENSDART00000091805
SH3 and multiple ankyrin repeat domains 3a
chr5_+_24287927 0.85 ENSDART00000143563
zinc finger, DHHC-type containing 23a
chr3_-_33574576 0.77 ENSDART00000184881

chr7_+_4384863 0.76 ENSDART00000042955
ENSDART00000134653
slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3
chr7_-_35515931 0.75 ENSDART00000193324
iroquois homeobox 6a
chr3_-_16227490 0.73 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
calcium channel, voltage-dependent, beta 1 subunit
chr21_-_20733615 0.72 ENSDART00000145544
si:ch211-22d5.2
chr1_-_7893808 0.70 ENSDART00000110154
Ras association and DIL domains
chr19_+_4061699 0.69 ENSDART00000158309
ENSDART00000166512
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr16_+_29555801 0.68 ENSDART00000169425
endosulfine alpha b
chr19_-_32944050 0.67 ENSDART00000137611
antizyme inhibitor 1b
chr4_-_760560 0.67 ENSDART00000103601
ATP/GTP binding protein-like 5
chr3_-_30941362 0.60 ENSDART00000076830
coronin, actin binding protein, 1A
chrM_+_12897 0.59 ENSDART00000093622
NADH dehydrogenase 5, mitochondrial
chr6_-_19270484 0.59 ENSDART00000186894
ENSDART00000188709
zgc:174863
chr13_-_36525982 0.58 ENSDART00000114744
phosphofurin acidic cluster sorting protein 2
chr14_+_44545092 0.56 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr8_+_2656231 0.55 ENSDART00000160833
family with sequence similarity 102, member Aa
chr7_+_17063761 0.55 ENSDART00000182880
HIV-1 Tat interactive protein 2
chr10_+_13279079 0.54 ENSDART00000135082
transmembrane protein 267
chr20_+_37295006 0.50 ENSDART00000153137
connexin 23
chr7_-_12821277 0.50 ENSDART00000091584
zgc:158785
chr25_+_19041329 0.45 ENSDART00000153467
leucine-rich repeats and transmembrane domains 2b
chr2_-_16986894 0.44 ENSDART00000145720
chloride channel, voltage-sensitive 2a
chr17_-_14559576 0.42 ENSDART00000162452
dishevelled associated activator of morphogenesis 1a
chr11_+_27973055 0.42 ENSDART00000135135
alkaline phosphatase, liver/bone/kidney
chr9_-_14084743 0.41 ENSDART00000056105
fer-1-like family member 6
chr2_-_9818640 0.38 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
adaptor-related protein complex 2, mu 1 subunit, b
chr2_-_42071558 0.37 ENSDART00000142792
centrosome and spindle pole associated protein 1b
chr2_+_30531726 0.35 ENSDART00000146518
ankyrin repeat domain 33Bb
chr19_+_24882845 0.35 ENSDART00000010580
si:ch211-195b13.1
chr21_-_36948 0.34 ENSDART00000181230
junction mediating and regulatory protein, p53 cofactor
chr3_+_52475058 0.32 ENSDART00000035867
si:ch211-241f5.3
chr7_+_30970045 0.31 ENSDART00000155974
tight junction protein 1a
chr24_+_3478871 0.30 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
WD repeat domain 37
chr1_+_16573982 0.28 ENSDART00000166317
microtubule associated tumor suppressor 1b
chr19_+_2275019 0.27 ENSDART00000136138
integrin, beta 8
chr5_-_33274645 0.27 ENSDART00000188584
kynurenine aminotransferase 1
chr17_-_50010121 0.26 ENSDART00000122747
transmembrane protein 30Aa
chr3_-_10970502 0.25 ENSDART00000127500

chr20_+_13533544 0.23 ENSDART00000143115
synaptotagmin-like 3
chr5_-_57526807 0.21 ENSDART00000022866
phosphatidylserine decarboxylase
chr16_-_31675669 0.20 ENSDART00000168848
ENSDART00000158331
complement component 1, r subcomponent
chr16_+_11297703 0.19 ENSDART00000125158
zinc finger protein 574
chr22_-_20695237 0.17 ENSDART00000112722
oogenesis-related gene
chr24_-_1303553 0.17 ENSDART00000190984
neuropilin 1a
chr7_+_20031202 0.16 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr8_+_48848200 0.16 ENSDART00000130673
tumor protein p73
chr5_+_67371650 0.13 ENSDART00000142156
SEBOX homeobox
chr8_+_21280360 0.13 ENSDART00000144488
inositol 1,4,5-trisphosphate receptor, type 3
chr5_+_8767290 0.12 ENSDART00000189377

chr23_-_28294763 0.11 ENSDART00000139537
zinc finger protein 385A
chr15_-_14486534 0.10 ENSDART00000179368
numb homolog (Drosophila)-like
chr21_-_35419486 0.10 ENSDART00000138529
si:dkeyp-23e4.3
chr3_-_58798815 0.09 ENSDART00000082920
si:ch73-281f12.4
chr25_-_22889519 0.09 ENSDART00000128250
MOB kinase activator 2a
chr7_-_50517023 0.09 ENSDART00000073910
ADAMTS like 5
chr7_-_18656069 0.08 ENSDART00000021559
coronin, actin binding protein, 1B
chr11_-_3366782 0.08 ENSDART00000127982
sulfite oxidase
chr20_+_32473584 0.08 ENSDART00000192449
osteopetrosis associated transmembrane protein 1
chr22_+_661505 0.06 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_+_33012407 0.06 ENSDART00000151873
si:dkey-26h11.2
chr24_+_5826005 0.04 ENSDART00000154930
si:ch211-157j23.5
chr17_-_32863250 0.04 ENSDART00000167292
prospero homeobox 1a
chr1_+_27690 0.03 ENSDART00000162928
embryonic ectoderm development
chr7_-_17780048 0.03 ENSDART00000183336
si:dkey-106g10.7
chr20_+_36629173 0.02 ENSDART00000161241
epoxide hydrolase 1, microsomal (xenobiotic)
chr18_-_25646286 0.02 ENSDART00000099511
ENSDART00000186890
si:ch211-13k12.2

Network of associatons between targets according to the STRING database.

First level regulatory network of gsc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.9 22.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.1 6.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.9 6.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 2.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 1.2 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.4 1.4 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 1.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 7.3 GO:0007634 optokinetic behavior(GO:0007634)
0.3 13.3 GO:0007602 phototransduction(GO:0007602)
0.3 1.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.7 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 2.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 2.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 8.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 1.0 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.2 2.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.0 GO:0016559 peroxisome fission(GO:0016559)
0.2 5.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 1.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.6 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 2.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 3.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0035608 protein deglutamylation(GO:0035608)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.8 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 2.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 2.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.0 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.3 GO:0008272 sulfate transport(GO:0008272)
0.1 3.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.3 GO:0036065 fucosylation(GO:0036065)
0.1 0.6 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.5 GO:0036269 swimming behavior(GO:0036269)
0.1 10.6 GO:0007601 visual perception(GO:0007601)
0.1 2.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.6 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.1 3.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 3.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 2.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 2.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.7 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 1.4 GO:0001503 ossification(GO:0001503)
0.0 5.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.4 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.9 13.6 GO:0060170 ciliary membrane(GO:0060170)
0.6 9.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.5 2.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.5 18.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 3.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 1.4 GO:0031673 H zone(GO:0031673)
0.3 4.1 GO:0044295 axonal growth cone(GO:0044295)
0.3 3.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 6.2 GO:0005861 troponin complex(GO:0005861)
0.1 2.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 8.5 GO:0030141 secretory granule(GO:0030141)
0.1 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.3 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 1.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.6 2.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.5 6.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.5 9.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.3 1.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.3 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.3 1.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 13.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 1.4 GO:0070004 dipeptidase activity(GO:0016805) cysteine-type exopeptidase activity(GO:0070004)
0.3 11.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 5.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 3.9 GO:0005080 protein kinase C binding(GO:0005080)
0.2 2.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 1.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 3.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 2.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 1.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 2.0 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.0 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 2.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 22.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.1 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 7.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.3 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 11.8 GO:0015293 symporter activity(GO:0015293)
0.1 2.4 GO:0030145 manganese ion binding(GO:0030145)
0.1 2.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.0 GO:0044325 ion channel binding(GO:0044325)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.2 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 1.6 GO:0051020 GTPase binding(GO:0051020)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 3.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 3.4 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 26.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 2.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 23.9 REACTOME OPSINS Genes involved in Opsins
2.4 9.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.0 2.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events