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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gmeb1

Z-value: 0.46

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Transcription factors associated with gmeb1

Gene Symbol Gene ID Gene Info
gmeb1
ENSDARG00000062060 glucocorticoid modulatory element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gmeb1dr11_v1_chr19_+_16064439_160644390.803.8e-05Click!

Activity profile of gmeb1 motif

Sorted Z-values of gmeb1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_45238292 1.15 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr25_+_34845115 1.13 ENSDART00000061996
tmem231
transmembrane protein 231
chr22_+_22437561 1.01 ENSDART00000089622
kif14
kinesin family member 14
chr3_-_15999501 0.98 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr21_+_6397463 0.87 ENSDART00000136539
si:ch211-225g23.1
si:ch211-225g23.1
chr3_-_16000168 0.87 ENSDART00000160628
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr16_-_41535690 0.73 ENSDART00000102662
rpp25l
ribonuclease P/MRP 25 subunit-like
chr4_+_23126558 0.72 ENSDART00000162859
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr8_+_10305400 0.64 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr10_-_20523405 0.59 ENSDART00000114824
ddhd2
DDHD domain containing 2
chr8_+_19489854 0.57 ENSDART00000184671
ENSDART00000011258
npl
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr25_-_34845302 0.56 ENSDART00000039485
gabarapl2
GABA(A) receptor-associated protein like 2
chr16_+_23397785 0.49 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr22_-_621888 0.48 ENSDART00000135829
srsf3b
serine/arginine-rich splicing factor 3b
chr9_-_306515 0.44 ENSDART00000166059
si:ch211-166e11.5
si:ch211-166e11.5
chr5_+_30588856 0.40 ENSDART00000086661
dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr1_+_19515228 0.38 ENSDART00000103091
clrn2
clarin 2
chr25_+_22281441 0.35 ENSDART00000089516
stoml1
stomatin (EPB72)-like 1
chr23_-_9807546 0.35 ENSDART00000136740
ENSDART00000004474
mapre1b
microtubule-associated protein, RP/EB family, member 1b
chr14_-_21932403 0.35 ENSDART00000054420
rad9a
RAD9 checkpoint clamp component A
chr12_+_11650146 0.35 ENSDART00000150191
waplb
WAPL cohesin release factor b
chr5_+_6955900 0.32 ENSDART00000099417
CABZ01041962.1

chr14_-_31489410 0.26 ENSDART00000018347
cab39l1
calcium binding protein 39, like 1
chr12_-_2869565 0.24 ENSDART00000152772
zdhhc16b
zinc finger, DHHC-type containing 16b
chr12_+_3571770 0.24 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr22_-_621609 0.22 ENSDART00000137264
ENSDART00000106636
srsf3b
serine/arginine-rich splicing factor 3b
chr20_+_27427112 0.19 ENSDART00000153459
si:dkey-22l1.1
si:dkey-22l1.1
chr10_+_39091716 0.18 ENSDART00000193072
si:ch73-1a9.4
si:ch73-1a9.4
chr3_+_46764278 0.17 ENSDART00000136051
ENSDART00000164930
prkcsh
protein kinase C substrate 80K-H
chr21_-_8153165 0.16 ENSDART00000182580
CABZ01074363.1

chr25_+_18711804 0.15 ENSDART00000011149
fam185a
family with sequence similarity 185, member A
chr12_-_11649690 0.15 ENSDART00000149713
btbd16
BTB (POZ) domain containing 16
chr2_-_3045861 0.15 ENSDART00000105818
ENSDART00000187575
guk1a
guanylate kinase 1a
chr16_-_24815091 0.15 ENSDART00000154269
ENSDART00000131025
kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr17_-_25831569 0.13 ENSDART00000148743
hhat
hedgehog acyltransferase
chr10_+_26990095 0.13 ENSDART00000064111
faub
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b

Network of associatons between targets according to the STRING database.

First level regulatory network of gmeb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 1.9 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0007634 optokinetic behavior(GO:0007634)
0.0 1.3 GO:0007224 smoothened signaling pathway(GO:0007224)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein