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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gli2a+gli3

Z-value: 0.76

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Transcription factors associated with gli2a+gli3

Gene Symbol Gene ID Gene Info
ENSDARG00000025641 GLI family zinc finger 2a
ENSDARG00000052131 GLI family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli2adr11_v1_chr9_+_37141836_37141836-0.871.7e-06Click!
gli3dr11_v1_chr24_-_11821505_11821505-0.804.1e-05Click!

Activity profile of gli2a+gli3 motif

Sorted Z-values of gli2a+gli3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_3252950 5.60 ENSDART00000020671
peripherin 2b (retinal degeneration, slow)
chr16_+_52512025 4.00 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr10_-_22854758 3.16 ENSDART00000079449
actinodin3
chr5_+_51594209 2.24 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
creatine kinase, mitochondrial 2b (sarcomeric)
chr6_-_35446110 2.23 ENSDART00000058773
regulator of G protein signaling 16
chr13_+_3954540 2.01 ENSDART00000092646
leucine rich repeat containing 73
chr21_+_10739846 1.95 ENSDART00000084011
complexin 4a
chr19_-_40192249 1.95 ENSDART00000051972
granulin 1
chr2_+_51783120 1.94 ENSDART00000177559
crystallin, gamma N1
chr23_-_27875140 1.85 ENSDART00000143662
ankyrin repeat domain 33Aa
chr17_-_51202339 1.75 ENSDART00000167117
si:ch1073-469d17.2
chr23_+_28582865 1.64 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr2_-_30784502 1.56 ENSDART00000056735
regulator of G protein signaling 20
chr25_-_210730 1.56 ENSDART00000187580

chr12_-_464007 1.55 ENSDART00000106669
dehydrogenase/reductase (SDR family) member 7Cb
chr15_+_7992906 1.53 ENSDART00000090790
cell adhesion molecule 2b
chr2_-_57707039 1.52 ENSDART00000097685

chr4_+_72797711 1.47 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr19_-_10243148 1.47 ENSDART00000148073
shisa family member 7
chr4_-_55785014 1.46 ENSDART00000181348

chr4_-_55801210 1.46 ENSDART00000186943

chr4_-_55829342 1.46 ENSDART00000185611

chr20_+_27194833 1.44 ENSDART00000150072
si:dkey-85n7.8
chr4_-_17741513 1.43 ENSDART00000141680
myosin binding protein C, slow type
chr25_-_17403598 1.43 ENSDART00000104216
cytochrome P450, family 2, subfamily X, polypeptide 9
chr16_+_20220225 1.32 ENSDART00000182208
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr23_+_20422661 1.28 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr6_-_10320676 1.26 ENSDART00000151247
sodium channel, voltage-gated, type I like, alpha b
chr23_+_43834376 1.25 ENSDART00000148989
si:ch211-149b19.4
chr5_-_20678300 1.24 ENSDART00000088639
WSC domain containing 2
chr10_-_35542071 1.24 ENSDART00000162139
si:ch211-244c8.4
chr4_-_75175407 1.22 ENSDART00000180125

chr18_+_9641210 1.21 ENSDART00000182024
piccolo presynaptic cytomatrix protein b
chr10_+_29963518 1.11 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
neurotrimin
chr1_-_19845378 1.09 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr15_+_16525126 1.08 ENSDART00000193455
polypeptide N-acetylgalactosaminyltransferase 17
chr19_+_9050852 1.06 ENSDART00000151031
ash1 (absent, small, or homeotic)-like (Drosophila)
chr20_-_915234 1.05 ENSDART00000164816
cannabinoid receptor 1
chr1_-_17797802 1.04 ENSDART00000041215
sorbin and SH3 domain containing 2a
chr1_-_46862190 1.04 ENSDART00000145167
1-acylglycerol-3-phosphate O-acyltransferase 3
chr25_+_30298377 1.02 ENSDART00000153622
chromosome 11 open reading frame 96
chr18_+_9635178 1.00 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr6_+_54358529 0.99 ENSDART00000153704
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr22_-_10487490 0.93 ENSDART00000064798
asporin (LRR class 1)
chr4_+_5132951 0.92 ENSDART00000103279
cyclin D2, b
chr16_-_31644545 0.90 ENSDART00000181634

chr1_+_9557212 0.89 ENSDART00000111131
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr5_-_17876709 0.88 ENSDART00000141978
si:dkey-112e17.1
chr7_-_2129076 0.87 ENSDART00000182385
si:cabz01007807.1
chr11_+_30314885 0.87 ENSDART00000187418
ENSDART00000123244
UDP glucuronosyltransferase 1 family, polypeptide B2
chr12_+_24562667 0.86 ENSDART00000056256
neurexin 1a
chr16_+_42667560 0.86 ENSDART00000023452
dpy-19-like 1, like (H. sapiens)
chr16_+_37470717 0.84 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adhesion G protein-coupled receptor B1a
chr2_+_50738325 0.80 ENSDART00000114182
FYVE and coiled-coil domain containing 1b
chr22_+_38173960 0.80 ENSDART00000010537
ceruloplasmin
chr8_-_47800754 0.80 ENSDART00000115050
ENSDART00000133669
KN motif and ankyrin repeat domains 3
chr5_+_13521081 0.79 ENSDART00000171975
si:ch211-230g14.6
chr9_-_46072805 0.79 ENSDART00000169682
histone deacetylase 4
chr8_+_31119548 0.79 ENSDART00000136578
synapsin I
chr2_-_30784198 0.78 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr3_-_46410387 0.78 ENSDART00000156822
cell death-inducing p53 target 1
chr5_+_36768674 0.75 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr18_+_16963881 0.74 ENSDART00000147583
si:ch211-242e8.1
chr7_+_73780936 0.73 ENSDART00000092691
proliferation and apoptosis adaptor protein 15
chr25_-_28384954 0.71 ENSDART00000073500
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr4_-_2219705 0.68 ENSDART00000131046
si:ch73-278m9.1
chr5_-_58112032 0.68 ENSDART00000016418
dopamine receptor D2b
chr17_+_30587333 0.65 ENSDART00000156500
NHS-like 1a
chr21_-_30935262 0.63 ENSDART00000172390
stromal interaction molecule 1b
chr17_-_7371564 0.62 ENSDART00000060336
RAB32b, member RAS oncogene family
chr8_-_40075983 0.62 ENSDART00000141455
gamma-glutamyltransferase 1a
chr19_+_32201991 0.62 ENSDART00000022667
family with sequence similarity 8, member A1a
chr8_+_47342586 0.61 ENSDART00000007624
phospholipase C, eta 2a
chr14_+_25464681 0.61 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr6_+_10094061 0.60 ENSDART00000150998
ENSDART00000162236
ATPase copper transporting beta
chr16_-_4026265 0.59 ENSDART00000149339
si:ch211-175f12.2
chr5_+_36439405 0.58 ENSDART00000102973
ectodysplasin A
chr8_-_49201258 0.58 ENSDART00000114584
ENSDART00000142172
zgc:171501
chr20_-_38610360 0.58 ENSDART00000168783
ENSDART00000164638
solute carrier family 30 (zinc transporter), member 2
chr2_+_54086436 0.57 ENSDART00000174581

chr10_-_44411032 0.56 ENSDART00000111509

chr10_+_2232023 0.55 ENSDART00000097695
contactin associated protein like 3
chr7_-_15413019 0.55 ENSDART00000172147
si:ch211-106j24.1
chr8_-_18316482 0.53 ENSDART00000190156
ring finger protein 220b
chr16_+_50741154 0.53 ENSDART00000101627
zgc:110372
chr12_-_46145635 0.50 ENSDART00000074682
zgc:153932
chr8_-_7078575 0.50 ENSDART00000137413
si:ch73-233m11.2
chr25_+_7461624 0.50 ENSDART00000170569
synaptotagmin XII
chr1_+_7956030 0.50 ENSDART00000159655

chr17_+_31580960 0.49 ENSDART00000188157
si:dkey-13p1.4
chr20_-_35052823 0.47 ENSDART00000153033
kinesin family member 26Bb
chr13_-_15799391 0.47 ENSDART00000124688
BCL2 associated athanogene 5
chr21_+_22985078 0.46 ENSDART00000156491
lysophosphatidic acid receptor 6b
chr2_+_47718605 0.46 ENSDART00000189180
ENSDART00000148824
muscleblind-like splicing regulator 1
chr3_-_19091024 0.45 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr20_-_7000225 0.43 ENSDART00000100098
adenylate cyclase 1a
chr2_+_48638827 0.43 ENSDART00000163634

chr5_+_20437124 0.43 ENSDART00000159001
transmembrane protein 119a
chr14_+_46020282 0.42 ENSDART00000190087
C1q and TNF related 2
chr21_-_5856050 0.42 ENSDART00000115367

chr3_+_5083407 0.41 ENSDART00000146883
si:ch73-338o16.4
chr12_-_26582607 0.41 ENSDART00000045186
solute carrier family 16 (monocarboxylate transporter), member 5a
chr7_+_73801377 0.40 ENSDART00000184051
si:ch73-252p3.1
chr19_+_56351 0.40 ENSDART00000168334
collagen, type XIV, alpha 1b
chr6_+_7123980 0.40 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
chr14_+_25465346 0.40 ENSDART00000173436
si:dkey-280e21.3
chr10_+_26747755 0.39 ENSDART00000100329
coagulation factor IXb
chr22_-_188102 0.39 ENSDART00000125391
ENSDART00000170463

chr3_-_18805225 0.38 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr7_-_15413188 0.37 ENSDART00000185980
si:ch211-106j24.1
chr20_+_10498704 0.37 ENSDART00000192985
zgc:100997
chr24_-_39354829 0.36 ENSDART00000169108
potassium inwardly-rectifying channel, subfamily J, member 12a
chr21_-_26520629 0.35 ENSDART00000142731
Ras converting CAAX endopeptidase 1b
chr20_-_6131686 0.35 ENSDART00000145964
ENSDART00000086578
ENSDART00000164090
pumilio RNA-binding family member 2
chr9_-_11655031 0.34 ENSDART00000044314
integrin, alpha V
chr17_-_34952562 0.33 ENSDART00000021128
kinase D-interacting substrate 220a
chr15_+_42431198 0.33 ENSDART00000189951
ENSDART00000089694
T cell lymphoma invasion and metastasis 1b
chr4_-_38476901 0.32 ENSDART00000167124
si:ch211-209n20.59
chr17_-_8562586 0.32 ENSDART00000154257
ENSDART00000157308
frizzled class receptor 3b
chr25_+_32473433 0.30 ENSDART00000152326
sulfide quinone oxidoreductase
chr10_-_24868581 0.29 ENSDART00000193055

chr18_+_22793743 0.29 ENSDART00000150106
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr15_-_19128705 0.27 ENSDART00000152428
Rho GTPase activating protein 32a
chr13_-_45201300 0.27 ENSDART00000074750
ENSDART00000180265
runt-related transcription factor 3
chr19_-_26235219 0.27 ENSDART00000104008
dystrobrevin binding protein 1b
chr23_-_41824460 0.26 ENSDART00000131235
si:ch73-302a13.2
chr4_+_4902392 0.24 ENSDART00000133866
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr9_-_33136990 0.22 ENSDART00000131742
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3b
chr11_-_23025949 0.22 ENSDART00000184859
ENSDART00000167818
ENSDART00000046122
ENSDART00000193120
ATPase plasma membrane Ca2+ transporting 2
chr14_-_41091667 0.22 ENSDART00000170042
dystrophin related protein 2
chr24_-_6258869 0.22 ENSDART00000006636
ENSDART00000178667
myosin IIIA
chr6_-_15639087 0.21 ENSDART00000128940
ENSDART00000183092
melanophilin a
chr10_+_18952271 0.21 ENSDART00000146517
dihydropyrimidinase-like 2b
chr23_-_14057191 0.21 ENSDART00000154908
adenylate cyclase 6a
chr25_+_22730490 0.21 ENSDART00000149455
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr3_+_57991074 0.21 ENSDART00000076077
myeloid-associated differentiation marker-like 2
chr7_+_34790768 0.18 ENSDART00000075116
si:dkey-148a17.6
chr11_+_36355348 0.18 ENSDART00000145427
synaptophysin-like 2a
chr25_-_24247584 0.17 ENSDART00000046349
SPT2 chromatin protein domain containing 1
chr17_-_4252221 0.17 ENSDART00000152020
growth differentiation factor 3
chr3_+_56574623 0.17 ENSDART00000130877
Rac family small GTPase 1b
chr20_-_35052464 0.15 ENSDART00000037195
kinesin family member 26Bb
chr24_-_25184553 0.15 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr14_+_30774515 0.15 ENSDART00000191666
atlastin 3
chr11_+_440305 0.15 ENSDART00000082517
RAB43, member RAS oncogene family
chr8_-_14484599 0.14 ENSDART00000057644
LIM homeobox 4
chr19_+_7954679 0.14 ENSDART00000150909
si:dkey-266f7.10
chr21_-_38619305 0.13 ENSDART00000139178
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr18_-_17485419 0.12 ENSDART00000018764
forkhead box L1
chr7_-_8374950 0.12 ENSDART00000057101
aerolysin-like protein
chr10_+_40235959 0.12 ENSDART00000145862
GRAM domain containing 1Ba
chr1_+_10129099 0.11 ENSDART00000187740
RNA binding motif protein 46
chr8_+_28467893 0.11 ENSDART00000189724
solute carrier family 52 (riboflavin transporter), member 3
chr14_+_49152341 0.11 ENSDART00000084114
nuclear receptor binding SET domain protein 1a
chr5_-_23715861 0.10 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr5_+_20599658 0.10 ENSDART00000143019
si:ch211-240b21.4
chr3_-_51109286 0.09 ENSDART00000172010
si:ch211-148f13.1
chr17_+_6563307 0.09 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr16_-_7827517 0.09 ENSDART00000189975
T cell activation inhibitor, mitochondrial
chr22_+_38762693 0.09 ENSDART00000015016
ENSDART00000150187
alkaline phosphatase, intestinal, tandem duplicate 1
chr24_+_7828613 0.08 ENSDART00000135161
zgc:101569
chr20_+_2669017 0.08 ENSDART00000058777
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr6_-_8480815 0.08 ENSDART00000162300
RAS protein activator like 3
chr13_-_865193 0.07 ENSDART00000187053

chr24_-_10828560 0.05 ENSDART00000132282
family with sequence similarity 49, member Bb
chr5_-_31926906 0.05 ENSDART00000187340
slingshot protein phosphatase 1b
chr14_-_215051 0.04 ENSDART00000054822
NK3 homeobox 2
chr9_-_12736089 0.04 ENSDART00000088042
myosin X-like 3
chr14_+_30774032 0.04 ENSDART00000139552
atlastin 3
chr21_+_35327589 0.03 ENSDART00000145191
ENSDART00000132743
arginyl-tRNA synthetase
chr4_+_38937575 0.02 ENSDART00000150385
zinc finger protein 997
chr22_+_1751640 0.02 ENSDART00000162093
zinc finger protein 1169
chr16_-_37964325 0.01 ENSDART00000148801
melanocortin 2 receptor accessory protein 2a
chr20_+_26095530 0.01 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr4_+_64921810 0.00 ENSDART00000157654

Network of associatons between targets according to the STRING database.

First level regulatory network of gli2a+gli3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.9 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 2.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 0.8 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 2.2 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 1.0 GO:0038171 cannabinoid signaling pathway(GO:0038171) positive regulation of feeding behavior(GO:2000253)
0.1 0.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.4 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.6 GO:0031179 peptide modification(GO:0031179)
0.1 0.3 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.1 1.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.3 GO:0014823 response to activity(GO:0014823)
0.1 0.7 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 2.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 7.2 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0032438 melanosome organization(GO:0032438)
0.0 1.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 1.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.5 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.8 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.6 GO:0042476 odontogenesis(GO:0042476)
0.0 1.4 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.8 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.1 GO:0016586 RSC complex(GO:0016586)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.0 GO:0043195 terminal bouton(GO:0043195)
0.1 1.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0032052 bile acid binding(GO:0032052)
0.4 1.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 2.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 2.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.4 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.6 GO:0030546 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 2.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels