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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gfi1aa+gfi1ab

Z-value: 0.83

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Transcription factors associated with gfi1aa+gfi1ab

Gene Symbol Gene ID Gene Info
ENSDARG00000020746 growth factor independent 1A transcription repressor a
ENSDARG00000044457 growth factor independent 1A transcription repressor b
ENSDARG00000114140 growth factor independent 1A transcription repressor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gfi1aadr11_v1_chr2_+_10771787_10771787-0.331.7e-01Click!
gfi1abdr11_v1_chr6_-_29007493_29007493-0.077.7e-01Click!

Activity profile of gfi1aa+gfi1ab motif

Sorted Z-values of gfi1aa+gfi1ab motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_54013457 1.09 ENSDART00000012104
ENSDART00000126339
deltaA
chr23_-_21471022 1.07 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr3_-_1400309 1.06 ENSDART00000159893
WW domain binding protein 11
chr16_+_20915319 1.05 ENSDART00000079383
homeobox A9b
chr11_-_10456553 1.00 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
epithelial cell transforming 2
chr12_+_27127139 1.00 ENSDART00000025966
homeobox B6b
chr23_+_21459263 0.93 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr5_-_54714789 0.92 ENSDART00000063357
cyclin B1
chr11_-_10456387 0.89 ENSDART00000011087
ENSDART00000081827
epithelial cell transforming 2
chr9_-_18877597 0.89 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr4_+_9508505 0.87 ENSDART00000080842
kit ligand b
chr24_+_19518570 0.87 ENSDART00000056081
sulfatase 1
chr24_+_19518303 0.86 ENSDART00000027022
ENSDART00000056080
sulfatase 1
chr5_-_19400166 0.85 ENSDART00000008994
forkhead box N4
chr6_-_53326421 0.84 ENSDART00000191740
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr1_+_31573225 0.83 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr23_-_21453614 0.83 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr14_-_26704829 0.82 ENSDART00000078563
neurogenin 1
chr23_+_8797143 0.81 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr23_+_21455152 0.81 ENSDART00000158511
ENSDART00000161321
ENSDART00000160731
ENSDART00000137573
hairy-related 4, tandem duplicate 2
chr8_+_15254564 0.77 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr25_-_7520937 0.77 ENSDART00000170050
cyclin-dependent kinase inhibitor 1Cb
chr14_-_39074539 0.76 ENSDART00000030509
glycine receptor, alpha 4a
chr15_-_15468326 0.76 ENSDART00000161192
RAB34, member RAS oncogene family a
chr21_+_33187992 0.76 ENSDART00000162745
ENSDART00000188388

chr5_-_54714525 0.75 ENSDART00000150138
ENSDART00000150070
cyclin B1
chr19_-_18152942 0.75 ENSDART00000190182
nuclear factor, erythroid 2-like 3
chr20_-_48485354 0.73 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr9_-_3400727 0.72 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr19_-_18152407 0.72 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr16_-_20312146 0.71 ENSDART00000134980
si:dkeyp-86h10.3
chr3_+_41922114 0.70 ENSDART00000138280
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_16330368 0.70 ENSDART00000128932
epiphycan
chr19_-_28130658 0.69 ENSDART00000079114
iroquois homeobox 1b
chr3_-_32859335 0.69 ENSDART00000158916
si:dkey-16l2.20
chr4_-_17353100 0.68 ENSDART00000134467
ENSDART00000189019
PARP1 binding protein
chr12_-_28848015 0.67 ENSDART00000153200
si:ch211-194k22.8
chr24_-_8729531 0.67 ENSDART00000082346
transcription factor AP-2 alpha
chr1_+_59538755 0.66 ENSDART00000166354
Sp6 transcription factor
chr5_-_54712159 0.66 ENSDART00000149207
cyclin B1
chr8_+_28371496 0.66 ENSDART00000158788
kelch-like family member 12
chr20_-_25645150 0.65 ENSDART00000063137
si:dkeyp-117h8.4
chr15_-_4528326 0.65 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr23_-_9855627 0.65 ENSDART00000180159
protein kinase C binding protein 1, like
chr11_-_40519886 0.65 ENSDART00000172819
migration and invasion inhibitory protein
chr12_+_27055900 0.64 ENSDART00000153198
fibrosin
chr12_-_8958353 0.64 ENSDART00000041728
cytochrome P450, family 26, subfamily A, polypeptide 1
chr21_-_929448 0.63 ENSDART00000133976
thioredoxin-like 1
chr19_+_9455218 0.63 ENSDART00000139385
si:ch211-288g17.3
chr20_+_26940178 0.62 ENSDART00000190888
cell division cycle associated 4
chr23_-_1056808 0.62 ENSDART00000081961
zgc:113423
chr19_-_35439237 0.62 ENSDART00000145883
anillin, actin binding protein
chr8_+_54055390 0.62 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr7_-_34184282 0.62 ENSDART00000183284
SMAD family member 6a
chr16_+_26706519 0.61 ENSDART00000142706
vir like m6A methyltransferase associated
chr12_+_16087077 0.61 ENSDART00000141898
zinc finger protein 281b
chr23_+_36178104 0.61 ENSDART00000103131
homeobox C1a
chr12_+_10706772 0.61 ENSDART00000158227
DNA topoisomerase II alpha
chr10_-_6427362 0.61 ENSDART00000166774
carbonic anhydrase IX
chr9_+_28232522 0.60 ENSDART00000031761
frizzled class receptor 5
chr5_-_36948586 0.60 ENSDART00000193606
H3 histone, family 3C
chr13_-_16222388 0.59 ENSDART00000182861
zgc:110045
chr20_+_26939742 0.59 ENSDART00000138369
ENSDART00000062061
ENSDART00000152992
cell division cycle associated 4
chr20_-_26491567 0.59 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr1_-_45584407 0.58 ENSDART00000149155
activating transcription factor 7 interacting protein
chr1_+_23563691 0.58 ENSDART00000142879
non-SMC condensin I complex, subunit G
chr22_-_2922053 0.58 ENSDART00000178290
p21 protein (Cdc42/Rac)-activated kinase 2b
chr11_+_14104417 0.57 ENSDART00000059752
ENSDART00000186575
mediator complex subunit 16
chr20_-_18535502 0.57 ENSDART00000049437
CDC42 binding protein kinase beta (DMPK-like)
chr7_-_18598661 0.56 ENSDART00000182109
si:ch211-119e14.2
chr2_+_49522178 0.55 ENSDART00000056254
signal transducing adaptor family member 2a
chr1_-_38195012 0.55 ENSDART00000020409
heart and neural crest derivatives expressed 2
chr13_+_46941930 0.55 ENSDART00000056962
F-box protein 5
chr17_+_15433671 0.54 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr12_+_25600685 0.54 ENSDART00000077157
SIX homeobox 3b
chr22_-_10541372 0.53 ENSDART00000179708
si:dkey-42i9.4
chr8_+_16738282 0.53 ENSDART00000134265
ENSDART00000100698
excision repair cross-complementation group 8
chr1_-_50590626 0.53 ENSDART00000146892
ENSDART00000022733
ATP-binding cassette, sub-family G (WHITE), member 2d
chr2_-_47431205 0.53 ENSDART00000014350
ENSDART00000038828
paired box 3a
chr11_+_45343245 0.53 ENSDART00000160904
si:ch73-100l22.3
chr2_-_29996036 0.52 ENSDART00000020792
canopy1
chr7_-_26603743 0.52 ENSDART00000099003
phospholipid scramblase 3b
chr16_-_7443388 0.51 ENSDART00000017445
PR domain containing 1a, with ZNF domain
chr13_-_45022301 0.51 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
KH domain containing, RNA binding, signal transduction associated 1a
chr8_+_18010978 0.51 ENSDART00000039887
ENSDART00000144532
single stranded DNA binding protein 3b
chr5_-_45958838 0.51 ENSDART00000135072
POC5 centriolar protein homolog (Chlamydomonas)
chr2_-_48753873 0.51 ENSDART00000189556

chr25_-_15049694 0.50 ENSDART00000162485
ENSDART00000164384
ENSDART00000165632
ENSDART00000159490
paired box 6a
chr3_-_26244256 0.50 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr22_+_22437561 0.50 ENSDART00000089622
kinesin family member 14
chr3_+_23703704 0.50 ENSDART00000024256
homeobox B6a
chr13_+_28612313 0.50 ENSDART00000077383
BLOC-1 related complex subunit 7
chr5_-_23179319 0.49 ENSDART00000161883
ENSDART00000136260
si:dkey-114c15.5
chr22_-_506522 0.49 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr9_+_3388099 0.49 ENSDART00000019910
distal-less homeobox 1a
chr17_-_36936649 0.48 ENSDART00000145236
dihydropyrimidinase-like 5a
chr14_+_30491890 0.48 ENSDART00000131174
fibroblast growth factor 20b
chr22_+_396840 0.48 ENSDART00000163198
capping protein (actin filament) muscle Z-line, beta
chr4_-_12477224 0.48 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr1_+_34701144 0.48 ENSDART00000150038
general transcription factor IIF, polypeptide 2a
chr13_+_51579851 0.48 ENSDART00000163847
NK6 homeobox 2
chr18_-_14836600 0.48 ENSDART00000045232
metastasis suppressor 1-like a
chr24_+_41690545 0.48 ENSDART00000160069
laminin, alpha 1
chr4_+_4803698 0.48 ENSDART00000129252
solute carrier family 13 (sodium/sulfate symporter), member 4
chr3_-_56030117 0.48 ENSDART00000113030
ENSDART00000157764
centrosomal protein 112
chr7_-_16598212 0.47 ENSDART00000128488
E2F transcription factor 8
chr13_+_4671698 0.47 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
phospholipase A2, group XIIB
chr2_+_48288461 0.47 ENSDART00000141495
hes family bHLH transcription factor 6
chr12_+_27536095 0.47 ENSDART00000013033
ets variant 4
chr21_-_26495700 0.47 ENSDART00000109379
CD248 molecule, endosialin b
chr3_+_32135037 0.47 ENSDART00000110490

chr13_-_39159810 0.47 ENSDART00000131508
collagen, type IX, alpha 1b
chr8_-_2591654 0.46 ENSDART00000049109
SET nuclear proto-oncogene a
chr21_+_30351256 0.46 ENSDART00000078341
forkhead box I3a
chr2_-_16562505 0.46 ENSDART00000156406
ATPase Na+/K+ transporting subunit beta 3a
chr21_+_25068215 0.45 ENSDART00000167523
ENSDART00000189259
DIX domain containing 1b
chr6_+_36821621 0.45 ENSDART00000104157
transmembrane protein 45a
chr10_-_26274094 0.45 ENSDART00000108798
dachsous cadherin-related 1b
chr13_+_24263049 0.45 ENSDART00000135992
ENSDART00000088005
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr13_+_30912385 0.45 ENSDART00000182642
dorsal root ganglia homeobox
chr17_+_23975762 0.44 ENSDART00000155941
exportin 1 (CRM1 homolog, yeast) b
chr16_+_813780 0.44 ENSDART00000162474
ENSDART00000161774
iroquois homeobox 1a
chr13_+_25433774 0.44 ENSDART00000141255
si:dkey-51a16.9
chr3_-_27072179 0.44 ENSDART00000156556
activating transcription factor 7 interacting protein 2
chr8_+_18010568 0.44 ENSDART00000121984
single stranded DNA binding protein 3b
chr9_-_48214216 0.44 ENSDART00000012938
phosphoglycerate dehydrogenase
chr5_+_17727310 0.44 ENSDART00000147657
fibrosin-like 1
chr22_+_23546926 0.44 ENSDART00000157940
abnormal spindle microtubule assembly
chr5_-_35252761 0.44 ENSDART00000051278
transportin 1
chr24_+_4978055 0.43 ENSDART00000045813
zic family member 4
chr21_+_35215810 0.43 ENSDART00000135256
ubiquitin domain containing 2
chr20_-_20533865 0.43 ENSDART00000125039
SIX homeobox 6b
chr16_+_33121260 0.43 ENSDART00000058472
akirin 1
chr13_-_39160018 0.43 ENSDART00000168795
collagen, type IX, alpha 1b
chr5_+_9259971 0.42 ENSDART00000163060
sushi domain containing 1
chr2_+_38227264 0.42 ENSDART00000192707
si:ch211-14a17.11
chr13_-_42536642 0.42 ENSDART00000134533
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr6_+_40563848 0.42 ENSDART00000154766
si:ch73-15b2.5
chr17_-_37795865 0.42 ENSDART00000025853
zinc finger protein 36, C3H type-like 1a
chr15_+_5901970 0.42 ENSDART00000114134
tryptophan rich basic protein
chr24_+_4977862 0.42 ENSDART00000114537
zic family member 4
chr8_+_37700090 0.42 ENSDART00000187885
ENSDART00000127633
adrenoceptor beta 3a
chr4_-_16412084 0.42 ENSDART00000188460
decorin
chr23_+_2421689 0.42 ENSDART00000180200
t-complex 1
chr23_+_9268083 0.41 ENSDART00000055054
acyl-CoA synthetase short chain family member 2
chr12_-_10476448 0.41 ENSDART00000106172
Rac family small GTPase 1a
chr4_+_646154 0.41 ENSDART00000171138
exportin, tRNA (nuclear export receptor for tRNAs)
chr22_-_10541712 0.41 ENSDART00000013933
si:dkey-42i9.4
chr17_-_43022468 0.41 ENSDART00000002945
zgc:193725
chr13_+_43650632 0.40 ENSDART00000141024
zinc finger, FYVE domain containing 21
chr1_-_20271138 0.40 ENSDART00000185931
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr12_+_22258962 0.40 ENSDART00000131175
wingless-type MMTV integration site family, member 3
chr8_+_25173317 0.40 ENSDART00000142006
G protein-coupled receptor 61
chr13_+_30912117 0.40 ENSDART00000133138
dorsal root ganglia homeobox
chr4_-_9867476 0.40 ENSDART00000091630
F-box protein, helicase, 18
chr25_+_27410352 0.40 ENSDART00000154362
protection of telomeres 1 homolog
chr2_-_45510699 0.40 ENSDART00000024034
ENSDART00000145634
G protein signaling modulator 2
chr25_-_17918536 0.40 ENSDART00000148660
aryl hydrocarbon receptor nuclear translocator-like 1a
chr18_+_16744307 0.40 ENSDART00000179872
ENSDART00000133490
lymphatic vessel endothelial hyaluronic receptor 1b
chr18_+_38749547 0.40 ENSDART00000143735
si:ch211-215d8.2
chr17_-_36936856 0.40 ENSDART00000010274
ENSDART00000188887
dihydropyrimidinase-like 5a
chr1_+_14658801 0.40 ENSDART00000192194

chr6_+_48154954 0.40 ENSDART00000019706
polyhomeotic homolog 2b (Drosophila)
chr24_+_21973929 0.39 ENSDART00000042495
spermidine/spermine N1-acetyltransferase 1b
chr8_+_39619087 0.39 ENSDART00000134822
musashi RNA-binding protein 1
chr19_+_37120491 0.39 ENSDART00000032341
penta-EF-hand domain containing 1
chr21_-_10773344 0.39 ENSDART00000063244
gastrin-releasing peptide
chr19_+_5146460 0.39 ENSDART00000150740
si:dkey-89b17.4
chr7_-_18470963 0.39 ENSDART00000173929
ENSDART00000173638
zinc finger protein 16 like
chr12_+_27536270 0.39 ENSDART00000133719
ets variant 4
chr8_+_2487250 0.38 ENSDART00000081325
dynein, light chain, LC8-type 1
chr5_+_9259574 0.38 ENSDART00000185560
sushi domain containing 1
chr25_-_23526058 0.38 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr6_+_35362225 0.38 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr4_-_5652030 0.38 ENSDART00000010903
radial spoke head 9 homolog
chr7_+_40638210 0.38 ENSDART00000052236
motor neuron and pancreas homeobox 1
chr11_+_14333441 0.37 ENSDART00000171969
polypyrimidine tract binding protein 1b
chr10_-_17550239 0.37 ENSDART00000057513
spindle and kinetochore associated complex subunit 1
chr23_+_36095260 0.37 ENSDART00000127384
homeobox C9a
chr9_-_43213057 0.37 ENSDART00000059448
ENSDART00000133589
SEC14 and spectrin domains 1
chr2_+_33926911 0.37 ENSDART00000109849
ENSDART00000135884
kinesin family member 2C
chr19_+_15521997 0.37 ENSDART00000003164
protein phosphatase 1, regulatory subunit 8a
chr20_-_29864390 0.37 ENSDART00000161834
ENSDART00000132278
ring finger protein 144ab
chr3_-_32541033 0.37 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr1_+_27825980 0.37 ENSDART00000160524
paraspeckle component 1
chr24_+_40860320 0.37 ENSDART00000161351
golgi reassembly stacking protein 1b
chr6_-_39518489 0.36 ENSDART00000185446
activating transcription factor 1
chr11_-_18017287 0.36 ENSDART00000155443
glutamine-rich 1
chr8_-_4892913 0.36 ENSDART00000126808
immunoglobulin superfamily, member 9b
chr6_-_11792152 0.36 ENSDART00000183403
membrane-associated ring finger (C3HC4) 7
chr13_-_45022527 0.36 ENSDART00000159021
KH domain containing, RNA binding, signal transduction associated 1a
chr13_+_31603988 0.36 ENSDART00000030646
SIX homeobox 6a
chr3_+_39568290 0.35 ENSDART00000020741
aldolase a, fructose-bisphosphate, a
chr17_-_21066075 0.35 ENSDART00000078763
ENSDART00000104327
visual system homeobox 1 homolog, chx10-like
chr5_+_43870389 0.35 ENSDART00000141002
zgc:112966
chr9_-_1984604 0.35 ENSDART00000082339
homeobox D12a
chr24_+_9881219 0.35 ENSDART00000036204
carnitine deficiency-associated gene expressed in ventricle 3
chr17_-_11439815 0.35 ENSDART00000130105
proteasome subunit alpha 3
chr10_+_43994471 0.34 ENSDART00000138242
ENSDART00000186359
claudin 5b
chr12_+_19191787 0.34 ENSDART00000152892
solute carrier family 16 (monocarboxylate transporter), member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of gfi1aa+gfi1ab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 1.8 GO:0055016 hypochord development(GO:0055016)
0.3 2.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 1.7 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.2 2.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.7 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 0.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.2 1.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.2 1.0 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.2 1.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.4 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 2.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.4 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.5 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.6 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 0.6 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 0.5 GO:0048327 axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
0.1 1.0 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 2.0 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 0.8 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.0 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.3 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.2 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.8 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.7 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 1.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.4 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.4 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.2 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.1 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.9 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.5 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.5 GO:0001709 cell fate determination(GO:0001709)
0.1 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:2000051 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.1 GO:0033340 pelvic fin development(GO:0033340)
0.0 0.5 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.2 GO:0043111 replication fork arrest(GO:0043111)
0.0 0.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.6 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0090505 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.0 0.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.7 GO:0048794 swim bladder development(GO:0048794)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.7 GO:0060840 artery development(GO:0060840)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:1900180 regulation of protein localization to nucleus(GO:1900180) positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.6 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.1 GO:0001840 neural plate development(GO:0001840)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.4 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.0 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 0.0 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.6 GO:0072175 epithelial tube formation(GO:0072175)
0.0 0.1 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.5 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.1 0.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.5 GO:0030175 filopodium(GO:0030175)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.9 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 0.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.3 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.8 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.4 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.3 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.5 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.4 GO:0019809 spermidine binding(GO:0019809)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0060182 apelin receptor activity(GO:0060182)
0.0 2.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 19.2 GO:0001159 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID P73PATHWAY p73 transcription factor network
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.3 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.4 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse