ISMARA results: gata1a+gata2b

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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gata1a+gata2b

Z-value: 0.16

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Transcription factors associated with gata1a+gata2b

Gene Symbol	Gene ID	Gene Info
gata2b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000009094	GATA binding protein 2b
gata1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000013477	GATA binding protein 1a
gata1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000117116	GATA binding protein 1a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
gata1a	dr11_v1_chr11_-_25418856_25418856	0.43	6.9e-02	Click!
gata2b	dr11_v1_chr6_+_40794015_40794015	0.17	4.9e-01	Click!

Activity profile of gata1a+gata2b motif

Sorted Z-values of gata1a+gata2b motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_12444943 Show fit	0.40	ENSDART00000135706	ldlrad4a NCBI UniProt ZFIN ENSEMBL Google Show fit	low density lipoprotein receptor class A domain containing 4a
chr10_-_31175744 Show fit	0.32	ENSDART00000191728	pknox2 NCBI UniProt ZFIN ENSEMBL Google Show fit	pbx/knotted 1 homeobox 2
chr22_+_635813 Show fit	0.28	ENSDART00000179067	CU856139.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr22_+_21398508 Show fit	0.25	ENSDART00000089408 ENSDART00000186091	shdb NCBI UniProt ZFIN ENSEMBL Google Show fit	Src homology 2 domain containing transforming protein D, b
chr5_+_18047111 Show fit	0.12	ENSDART00000132164	hira NCBI UniProt ZFIN ENSEMBL Google Show fit	histone cell cycle regulator a
chr10_+_42589391 Show fit	0.09	ENSDART00000067689 ENSDART00000075259	fgfr1b NCBI UniProt ZFIN ENSEMBL Google Show fit	fibroblast growth factor receptor 1b
chr6_-_49159207 Show fit	0.08	ENSDART00000041942	tspan2a NCBI UniProt ZFIN ENSEMBL Google Show fit	tetraspanin 2a
chr12_-_5505205 Show fit	0.07	ENSDART00000092319	abi3b NCBI UniProt ZFIN ENSEMBL Google Show fit	ABI family, member 3b
chr7_+_15329819 Show fit	0.07	ENSDART00000006018	mespaa NCBI UniProt ZFIN ENSEMBL Google Show fit	mesoderm posterior aa
chr22_+_15507218 Show fit	0.07	ENSDART00000125450	gpc1a NCBI UniProt ZFIN ENSEMBL Google Show fit	glypican 1a
chr19_-_32710922 Show fit	0.06	ENSDART00000004034	hpca NCBI UniProt ZFIN ENSEMBL Google Show fit	hippocalcin
chr18_+_3169579 Show fit	0.05	ENSDART00000164724 ENSDART00000186340 ENSDART00000181247 ENSDART00000168056	pak1 NCBI UniProt ZFIN ENSEMBL Google Show fit	p21 protein (Cdc42/Rac)-activated kinase 1
chr11_-_40457325 Show fit	0.04	ENSDART00000128442	tnfrsf1b NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor necrosis factor receptor superfamily, member 1B
chr22_-_16270462 Show fit	0.01	ENSDART00000105681	cdc14ab NCBI UniProt ZFIN ENSEMBL Google Show fit	cell division cycle 14Ab

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1a+gata2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0097101	blood vessel endothelial cell fate specification(GO:0097101)
0.0	0.1	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)