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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxo4

Z-value: 0.80

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Transcription factors associated with foxo4

Gene Symbol Gene ID Gene Info
ENSDARG00000055792 forkhead box O4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo4dr11_v1_chr14_+_30910114_309101140.795.7e-05Click!

Activity profile of foxo4 motif

Sorted Z-values of foxo4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_24002503 1.86 ENSDART00000164702
chitinase, acidic.2
chr13_-_33207367 1.71 ENSDART00000146138
ENSDART00000109667
ENSDART00000182741
thyroid hormone receptor interactor 11
chr15_+_46313082 1.69 ENSDART00000153830
si:ch1073-190k2.1
chr3_-_60142530 1.46 ENSDART00000153247
si:ch211-120g10.1
chr13_-_42400647 1.20 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr17_+_33158350 1.16 ENSDART00000104476
sorting nexin 9a
chr11_+_6819050 1.13 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr13_-_23665580 1.11 ENSDART00000144282
mitogen-activated protein kinase kinase kinase 21
chr22_+_38276024 1.06 ENSDART00000143792
REST corepressor 3
chr4_-_1720648 1.05 ENSDART00000103484
growth arrest-specific 2 like 3
chr21_-_41588129 1.04 ENSDART00000164125
creb3 regulatory factor
chr23_-_44677315 1.02 ENSDART00000143054
kinesin family member 1C
chr18_+_41561285 1.02 ENSDART00000169621
bromodomain adjacent to zinc finger domain, 1B
chr5_+_36611128 0.94 ENSDART00000097684
neuro-oncological ventral antigen 1
chr2_-_26720854 0.92 ENSDART00000148110
si:dkey-181m9.8
chr15_+_30157602 0.90 ENSDART00000047248
ENSDART00000123937
nemo-like kinase, type 2
chr2_-_31376606 0.89 ENSDART00000098988
ENSDART00000125746
clusterin-like 1 (retinal)
chr20_+_30445971 0.87 ENSDART00000153150
myelin transcription factor 1-like, a
chr5_-_40190949 0.87 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr22_-_3449282 0.86 ENSDART00000136798
protein tyrosine phosphatase, receptor type, s, a
chr16_-_13612650 0.85 ENSDART00000080372
D site albumin promoter binding protein b
chr22_-_3914162 0.84 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
major histocompatibility complex class I UMA
chr10_+_573667 0.84 ENSDART00000110384
SMAD family member 4a
chr2_-_50372467 0.83 ENSDART00000108900
contactin associated protein like 2b
chr4_-_14926637 0.83 ENSDART00000110199
PR domain containing 4
chr9_+_32358514 0.82 ENSDART00000144608
phospholipase C like 1
chr1_-_9940494 0.81 ENSDART00000138726
transmembrane protein 8A
chr9_+_2343096 0.80 ENSDART00000062292
ENSDART00000191722
ENSDART00000135180
activating transcription factor 2
chr22_+_3914318 0.78 ENSDART00000188774
ENSDART00000082034
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr15_+_46386261 0.77 ENSDART00000191793
immunoglobulin superfamily member 11
chr3_+_57038033 0.77 ENSDART00000162930
BAH domain and coiled-coil containing 1a
chr17_+_44030692 0.76 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr16_-_13613475 0.75 ENSDART00000139102
D site albumin promoter binding protein b
chr7_+_38278860 0.75 ENSDART00000016265
low density lipoprotein receptor-related protein 3
chr3_-_60711127 0.75 ENSDART00000184119
UBA-like domain containing 2
chr5_+_51079504 0.73 ENSDART00000097466
family with sequence similarity 169, member Aa
chr4_+_18804317 0.71 ENSDART00000101043
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr19_-_7272921 0.71 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
retinoid x receptor, beta a
chr25_+_22017182 0.71 ENSDART00000156517
si:dkey-217l24.1
chr9_+_17423941 0.70 ENSDART00000112884
ENSDART00000155233
kelch repeat and BTB (POZ) domain containing 7
chr17_-_7218481 0.70 ENSDART00000181967
sterile alpha motif domain containing 5
chr10_-_36633882 0.69 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr10_-_33343244 0.69 ENSDART00000164191
C2 calcium-dependent domain containing 2
chr21_-_2707768 0.68 ENSDART00000165384

chr15_-_18574716 0.67 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr20_-_19365875 0.65 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
chr22_+_26798853 0.65 ENSDART00000087576
ENSDART00000179780
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr21_-_13661631 0.65 ENSDART00000184408
patatin-like phospholipase domain containing 7a
chr9_+_9502610 0.64 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr1_+_51191049 0.64 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr5_+_55934129 0.63 ENSDART00000050969
transmembrane protein 150Ab
chr2_+_33189582 0.62 ENSDART00000145588
ENSDART00000136330
ENSDART00000139295
ENSDART00000086340
ring finger protein 220a
chr9_+_24088062 0.62 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr3_-_12227359 0.61 ENSDART00000167356
transcription factor AP-4 (activating enhancer binding protein 4)
chr2_-_24603325 0.61 ENSDART00000113356
CREB regulated transcription coactivator 1a
chr20_-_25533739 0.60 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr6_+_48862 0.59 ENSDART00000082954
methyl-CpG binding domain protein 5
chr19_+_40115977 0.59 ENSDART00000139802
si:ch211-173p18.3
chr12_-_22509069 0.59 ENSDART00000179755
ENSDART00000109707
neuralized E3 ubiquitin protein ligase 4
chr2_-_38035235 0.58 ENSDART00000075904
cerebellin 5
chr6_-_32999646 0.58 ENSDART00000159510
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr8_+_16990120 0.57 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr15_+_30158652 0.57 ENSDART00000190682
nemo-like kinase, type 2
chr14_-_33177935 0.57 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr23_-_7755373 0.57 ENSDART00000162868
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr15_-_30984557 0.57 ENSDART00000080328
neurofibromin 1a
chr23_-_12158685 0.57 ENSDART00000135035
family with sequence similarity 217, member B
chr5_-_68058168 0.56 ENSDART00000177026
ring finger protein 167
chr23_-_30787932 0.56 ENSDART00000135771
myelin transcription factor 1a
chr8_+_4803906 0.56 ENSDART00000045533
transmembrane protein 127
chr7_+_33372680 0.55 ENSDART00000193436
ENSDART00000099988
glucuronic acid epimerase b
chr19_+_20724347 0.55 ENSDART00000090757
K(lysine) acetyltransferase 2B
chr5_+_44846434 0.55 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr12_-_30338779 0.55 ENSDART00000192511
von Willebrand factor A domain containing 2
chr2_-_57227542 0.54 ENSDART00000182675
ENSDART00000159480
BTB (POZ) domain containing 2b
chr2_-_43850637 0.54 ENSDART00000136077
zinc finger E-box binding homeobox 1a
chr5_+_62340799 0.53 ENSDART00000074117
aspartoacylase
chr24_-_5932982 0.53 ENSDART00000138412
ENSDART00000135124
ENSDART00000007373
acyl-CoA binding domain containing 5a
chr5_+_1965296 0.53 ENSDART00000156224
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr6_-_35309661 0.52 ENSDART00000114960
nitric oxide synthase 1 (neuronal) adaptor protein a
chr19_+_2275019 0.52 ENSDART00000136138
integrin, beta 8
chr17_+_24632440 0.51 ENSDART00000157092
mitogen-activated protein kinase kinase kinase kinase 3b
chr7_+_9904627 0.51 ENSDART00000172824
ceramide synthase 3a
chr13_-_43599898 0.51 ENSDART00000084416
ENSDART00000145705
actin binding LIM protein 1a
chr5_-_18046053 0.51 ENSDART00000144898
ring finger protein 215
chr25_+_34938317 0.51 ENSDART00000042678
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr22_-_28777374 0.50 ENSDART00000188206
si:dkeyp-34c12.1
chr18_+_26829086 0.49 ENSDART00000098356
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr20_-_16849306 0.49 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr3_+_24458899 0.49 ENSDART00000156655
chromobox homolog 6b
chr2_-_52841762 0.49 ENSDART00000114682
ralA binding protein 1
chr23_+_10469955 0.48 ENSDART00000140557
tensin 2a
chr1_-_23596391 0.48 ENSDART00000155184
ligand dependent nuclear receptor corepressor-like
chr18_+_26829362 0.47 ENSDART00000132728
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr18_-_25177230 0.47 ENSDART00000013363
solute carrier organic anion transporter family, member 3A1
chr6_-_10305918 0.47 ENSDART00000090994
sodium channel, voltage-gated, type I like, alpha b
chr18_+_41560822 0.46 ENSDART00000158503
bromodomain adjacent to zinc finger domain, 1B
chr22_-_22231720 0.45 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr17_-_43399896 0.45 ENSDART00000156033
ENSDART00000156418
inositol-tetrakisphosphate 1-kinase b
chr22_-_18179214 0.45 ENSDART00000129576
si:ch211-125m10.6
chr8_+_17869225 0.45 ENSDART00000080079
solute carrier family 44, member 5b
chr18_-_21047580 0.44 ENSDART00000010189
insulin-like growth factor 1a receptor
chr10_+_213878 0.44 ENSDART00000135903
ENSDART00000138812
myelin protein zero-like 1 like
chr11_+_39959039 0.43 ENSDART00000024304
period circadian clock 3
chr7_+_40205394 0.43 ENSDART00000173742
ENSDART00000148390
non-SMC condensin II complex, subunit G2
chr11_+_2710530 0.43 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr2_+_55365727 0.43 ENSDART00000162943

chr13_+_1100197 0.42 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr23_-_1571682 0.42 ENSDART00000013635
F-box protein 30b
chr21_-_13662237 0.41 ENSDART00000091647
ENSDART00000151547
patatin-like phospholipase domain containing 7a
chr20_+_4060839 0.41 ENSDART00000178565
tripartite motif containing 67
chr2_-_44971551 0.41 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr17_+_25856671 0.41 ENSDART00000064817
WAPL cohesin release factor a
chr8_+_8643901 0.40 ENSDART00000142076
ENSDART00000075624
ubiquitin specific peptidase 11
chr20_-_2949028 0.40 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cyclin-dependent kinase 19
chr12_+_27213733 0.39 ENSDART00000133048
neighbor of brca1 gene 1a
chr7_-_50604626 0.39 ENSDART00000073903
ENSDART00000174031
CREB regulated transcription coactivator 3
chr16_+_22587661 0.39 ENSDART00000129612
ENSDART00000142241
Src homology 2 domain containing E
chr19_+_22074468 0.38 ENSDART00000136294
ENSDART00000090476
ATPase phospholipid transporting 9B
chr17_-_2690083 0.38 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr5_-_18897482 0.38 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr10_+_28428222 0.38 ENSDART00000135003
si:ch211-222e20.4
chr18_-_14836862 0.38 ENSDART00000124843
metastasis suppressor 1-like a
chr18_-_16590056 0.38 ENSDART00000143744
mgat4 family, member C
chr20_-_40119872 0.37 ENSDART00000191569
sodium/potassium transporting ATPase interacting 2
chr16_-_26820634 0.37 ENSDART00000111156
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_+_41459759 0.37 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr21_-_42202792 0.37 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr14_+_8710568 0.37 ENSDART00000169505
potassium channel, subfamily K, member 4a
chr5_+_22836364 0.37 ENSDART00000131885
si:ch211-26b3.2
chr10_-_41156348 0.37 ENSDART00000058622
AP2 associated kinase 1b
chr4_+_15954293 0.37 ENSDART00000132695
si:dkey-117n7.4
chr13_+_28701233 0.37 ENSDART00000135931
si:ch211-67n3.9
chr8_+_17838924 0.36 ENSDART00000170762
solute carrier family 44, member 5b
chr25_-_17528994 0.36 ENSDART00000061712
si:dkey-44k1.5
chr25_-_4525081 0.36 ENSDART00000184347
p53-induced death domain protein 1
chr15_+_39977461 0.36 ENSDART00000063786
calcium binding protein 39
chr2_-_5942115 0.36 ENSDART00000154489
transmembrane protein 125b
chr11_-_25733910 0.36 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr16_-_22251414 0.35 ENSDART00000158500
ENSDART00000179998
ATPase phospholipid transporting 8B2
chr3_-_51912019 0.35 ENSDART00000149914
apoptosis-associated tyrosine kinase a
chr12_+_27704015 0.35 ENSDART00000153256
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr15_+_20543770 0.35 ENSDART00000092357
small G protein signaling modulator 2
chr5_-_50371205 0.35 ENSDART00000157800
si:ch73-280o22.2
chr23_+_17981127 0.34 ENSDART00000012571
ENSDART00000145200
chitinase, acidic.6
chr19_+_12237945 0.34 ENSDART00000190034
grainyhead-like transcription factor 2b
chr2_-_58142854 0.34 ENSDART00000169909

chr24_+_14240196 0.34 ENSDART00000124740
nuclear receptor coactivator 2
chr12_-_979789 0.33 ENSDART00000128188
diacylglycerol lipase, beta
chr25_-_3139805 0.33 ENSDART00000166625
eosinophil peroxidase
chr5_-_20678300 0.33 ENSDART00000088639
WSC domain containing 2
chr6_-_30839763 0.33 ENSDART00000154228
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr21_-_9782502 0.33 ENSDART00000158836
Rho GTPase activating protein 24
chr3_-_45298487 0.33 ENSDART00000102245
3-phosphoinositide dependent protein kinase 1a
chr15_+_20843161 0.33 ENSDART00000153726
unc-51 like autophagy activating kinase 2
chr19_-_27315062 0.33 ENSDART00000141203
general transcription factor IIH, polypeptide 4
chr6_-_43882696 0.33 ENSDART00000064938
forkhead box P1b
chr24_-_19718077 0.32 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr11_+_21586335 0.32 ENSDART00000091182
zgc:101564
chr14_-_25452503 0.32 ENSDART00000148652
solute carrier family 26 (anion exchanger), member 2
chr17_+_19730001 0.32 ENSDART00000155025
gremlin 2, DAN family BMP antagonist a
chr22_+_4707663 0.32 ENSDART00000042194
ceramide synthase 4a
chr1_+_45839927 0.32 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr5_-_4931266 0.31 ENSDART00000067600
zinc finger and BTB domain containing 43
chr23_-_27608257 0.31 ENSDART00000026314
PHD finger protein 8
chr25_-_3647277 0.31 ENSDART00000166363
si:ch211-272n13.3
chr6_-_9565526 0.31 ENSDART00000151470
mitogen-activated protein kinase kinase kinase 2
chr2_-_42492201 0.31 ENSDART00000180762
ENSDART00000009093
extended synaptotagmin-like protein 2a
chr15_-_44052927 0.31 ENSDART00000166209
wu:fb44b02
chr13_-_23264724 0.30 ENSDART00000051886
si:dkey-103j14.5
chr1_-_37383741 0.30 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr22_+_1868983 0.30 ENSDART00000160135
si:dkey-15h8.17
chr22_+_23546926 0.30 ENSDART00000157940
abnormal spindle microtubule assembly
chr15_-_25365570 0.30 ENSDART00000152754
clustered mitochondria (cluA/CLU1) homolog a
chr6_+_7466223 0.30 ENSDART00000148908
erb-b2 receptor tyrosine kinase 3a
chr2_-_12243213 0.30 ENSDART00000113081
G protein-coupled receptor 158b
chr16_+_42667560 0.30 ENSDART00000023452
dpy-19-like 1, like (H. sapiens)
chr16_-_5612480 0.30 ENSDART00000157944

chr22_+_2660505 0.29 ENSDART00000135555
ENSDART00000031485
zinc finger protein 1162
chr4_-_14926106 0.29 ENSDART00000147629
PR domain containing 4
chr7_+_13995792 0.29 ENSDART00000091470
furin (paired basic amino acid cleaving enzyme) a
chr24_+_21192431 0.29 ENSDART00000152027
upstream transcription factor family member 3
chr13_-_4333181 0.29 ENSDART00000122406
zinc finger protein 318
chr24_-_23323526 0.29 ENSDART00000112256
ENSDART00000176903
zinc finger homeobox 4
chr16_+_38337783 0.29 ENSDART00000135008
GA binding protein transcription factor, beta subunit 2b
chr7_-_51749683 0.28 ENSDART00000083190
histone deacetylase 8
chr15_-_5720583 0.28 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr9_-_10532591 0.28 ENSDART00000175269
thrombospondin, type I, domain containing 7Ba
chr10_-_36214582 0.28 ENSDART00000166471
odorant receptor, family D, subfamily 109, member 11
chr21_+_40276569 0.28 ENSDART00000144436
si:ch211-218m3.13
chr8_+_40081403 0.28 ENSDART00000138036
leucine rich repeat containing 75Ba
chr13_+_9368621 0.28 ENSDART00000109126
Alstrom syndrome protein 1
chr20_-_40119090 0.28 ENSDART00000145592
sodium/potassium transporting ATPase interacting 2
chr20_-_52928541 0.28 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr14_-_36378494 0.28 ENSDART00000058503
glycoprotein M6Aa
chr7_+_60551133 0.27 ENSDART00000148038
leucine rich repeat and fibronectin type III domain containing 4b
chr15_-_3976035 0.27 ENSDART00000168061
si:ch73-309g22.1
chr9_-_2572790 0.27 ENSDART00000135076
ENSDART00000016710
secernin 3
chr3_+_55031685 0.27 ENSDART00000132587
N-methylpurine DNA glycosylase
chr18_-_14836600 0.27 ENSDART00000045232
metastasis suppressor 1-like a

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 0.8 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.2 2.2 GO:0006032 chitin catabolic process(GO:0006032)
0.2 0.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 0.6 GO:0061010 gall bladder development(GO:0061010)
0.2 0.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.8 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 1.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 1.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.8 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.6 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.1 0.4 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.8 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.3 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.2 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.1 0.3 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.2 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 1.0 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.9 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.0 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.0 0.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.8 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.1 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.7 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.3 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.8 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.4 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.7 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 1.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.4 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0086009 membrane repolarization(GO:0086009)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 0.6 GO:0010369 chromocenter(GO:0010369)
0.1 0.6 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.9 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 2.2 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.6 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 1.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.4 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.7 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 1.9 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 1.0 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis