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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxn1

Z-value: 0.74

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Transcription factors associated with foxn1

Gene Symbol Gene ID Gene Info
ENSDARG00000011879 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxn1dr11_v1_chr15_-_28148314_28148314-0.512.7e-02Click!

Activity profile of foxn1 motif

Sorted Z-values of foxn1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_51579851 1.09 ENSDART00000163847
NK6 homeobox 2
chr13_-_21650404 1.03 ENSDART00000078352
tetraspanin 14
chr21_-_4849029 1.00 ENSDART00000168930
ENSDART00000151019
notch 1a
chr14_+_21754521 0.93 ENSDART00000111839
lysine (K)-specific demethylase 2Ab
chr16_-_17258111 0.88 ENSDART00000079497
EMG1 N1-specific pseudouridine methyltransferase
chr18_+_619619 0.86 ENSDART00000159846
protogenin homolog a (Gallus gallus)
chr3_-_60175470 0.85 ENSDART00000156597
si:ch73-364h19.1
chr9_-_46415847 0.85 ENSDART00000009790
connexin 43.4
chr23_+_27652906 0.81 ENSDART00000077931
wingless-type MMTV integration site family, member 1
chr23_+_30898013 0.80 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr5_-_54554583 0.75 ENSDART00000158865
ENSDART00000158069
Sjogren syndrome nuclear autoantigen 1
chr9_-_52598343 0.75 ENSDART00000167922
X-ray repair complementing defective repair in Chinese hamster cells 5
chr16_+_48460873 0.74 ENSDART00000159902
exostosin glycosyltransferase 1a
chr13_+_18321140 0.73 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr19_-_14191592 0.73 ENSDART00000164594
T-box transcription factor Ta
chr25_+_2776511 0.72 ENSDART00000115280
neogenin 1b
chr16_-_27161410 0.70 ENSDART00000177503

chr3_+_58472305 0.69 ENSDART00000154122
si:ch211-165g14.1
chr12_-_10674606 0.69 ENSDART00000157919
mediator complex subunit 24
chr16_-_6205790 0.68 ENSDART00000038495
catenin (cadherin-associated protein), beta 1
chr24_+_21092156 0.67 ENSDART00000028542
coiled-coil domain containing 191
chr1_+_19930520 0.65 ENSDART00000158344
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr10_-_22803740 0.64 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr1_-_50791280 0.63 ENSDART00000181224

chr20_+_20484827 0.60 ENSDART00000048110
SIX homeobox 4b
chr4_-_11594202 0.60 ENSDART00000002682
neuroepithelial cell transforming 1
chr16_-_51072406 0.59 ENSDART00000083777
argonaute RISC catalytic component 3a
chr9_+_21793565 0.59 ENSDART00000134915
REV1, polymerase (DNA directed)
chr19_-_6193067 0.59 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr4_+_23117557 0.59 ENSDART00000066909
solute carrier family 35, member E3
chr8_+_54055390 0.58 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr4_-_18281070 0.57 ENSDART00000135330
ENSDART00000179075
ENSDART00000046871
UHRF1 binding protein 1-like
chr18_+_328689 0.57 ENSDART00000167841
synovial sarcoma translocation gene on chromosome 18-like 2
chr6_+_21684296 0.57 ENSDART00000057223
Ras homolog, mTORC1 binding like 1
chr23_+_23485858 0.57 ENSDART00000114067
agrin
chr1_-_59313465 0.56 ENSDART00000158067
ENSDART00000159419
thioredoxin domain containing 11
chr10_-_35177257 0.56 ENSDART00000077426
POM121 transmembrane nucleoporin
chr16_+_35870456 0.55 ENSDART00000184321
thyroid hormone receptor associated protein 3a
chr20_+_51730658 0.55 ENSDART00000010271
axin interactor, dorsalization associated
chr16_-_31505802 0.54 ENSDART00000147616
si:ch211-251p5.5
chr17_+_24064014 0.54 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr9_+_54984900 0.53 ENSDART00000191622
motile sperm domain containing 2
chr19_-_29303788 0.53 ENSDART00000112167
serum response factor binding protein 1
chr25_+_7532811 0.51 ENSDART00000161593
phosphatidylserine synthase 2
chr19_-_7272921 0.50 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
retinoid x receptor, beta a
chr6_-_59505589 0.49 ENSDART00000170685
GLI family zinc finger 1
chr14_-_21123325 0.49 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
chr20_+_25225112 0.49 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
monooxygenase, DBH-like 1
chr7_-_18547420 0.48 ENSDART00000173969
regulator of G protein signaling 12a
chr14_+_26439227 0.48 ENSDART00000054183
G protein-coupled receptor 137
chr14_-_83154 0.48 ENSDART00000187097

chr7_+_24006875 0.47 ENSDART00000033755
homeobox and leucine zipper encoding b
chr15_+_2421432 0.47 ENSDART00000193772
hephaestin-like 1a
chr12_+_2804505 0.47 ENSDART00000152193
MMS19 homolog, cytosolic iron-sulfur assembly component
chr5_+_23045096 0.46 ENSDART00000171719
alpha thalassemia/mental retardation syndrome X-linked, like
chr25_+_34845115 0.46 ENSDART00000061996
transmembrane protein 231
chr5_-_31901468 0.46 ENSDART00000147814
ENSDART00000141446
coronin, actin binding protein, 1Cb
chr5_-_19932621 0.46 ENSDART00000088881
G protein-coupled receptor kinase interacting ArfGAP 2a
chr16_-_48430272 0.46 ENSDART00000005927
RAD21 cohesin complex component a
chr4_-_119689 0.45 ENSDART00000161055
dual specificity phosphatase 16
chr15_+_2421729 0.45 ENSDART00000082294
ENSDART00000156428
hephaestin-like 1a
chr17_+_34186632 0.44 ENSDART00000014306
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr25_+_245018 0.44 ENSDART00000155344
zgc:92481
chr17_-_53022822 0.44 ENSDART00000103434
zgc:154061
chr19_+_5134624 0.43 ENSDART00000151324
si:dkey-89b17.4
chr19_+_26681848 0.43 ENSDART00000138322
si:dkey-27c15.3
chr5_+_63288599 0.43 ENSDART00000140065
si:ch73-37h15.2
chr2_+_35732652 0.43 ENSDART00000052666
RAS protein activator like 2
chr24_+_4373355 0.42 ENSDART00000179062
ENSDART00000093256
ENSDART00000138943
cyclin Y
chr19_+_19772765 0.42 ENSDART00000182028
ENSDART00000161019
homeobox A3a
chr14_-_4177311 0.42 ENSDART00000128129
si:dkey-185e18.7
chr4_-_74998614 0.42 ENSDART00000162529
zgc:172139
chr3_+_1055588 0.42 ENSDART00000143220
zgc:153921
chr6_-_35106425 0.42 ENSDART00000165139
nitric oxide synthase 1 (neuronal) adaptor protein a
chr25_+_7346800 0.41 ENSDART00000154404
pseudopodium-enriched atypical kinase 1
chr4_-_40589466 0.41 ENSDART00000133295
ENSDART00000124872
si:dkey-207m2.4
chr17_+_10593398 0.41 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr4_-_43640507 0.41 ENSDART00000150700
si:dkey-29p23.2
chr20_-_50014936 0.40 ENSDART00000148892
exostosin-like glycosyltransferase 3
chr23_+_35650771 0.40 ENSDART00000005158
cyclin T1
chr11_-_22605981 0.40 ENSDART00000186923
myogenin
chr9_+_54984537 0.40 ENSDART00000029528
motile sperm domain containing 2
chr6_+_20647155 0.38 ENSDART00000193477
solute carrier family 19 (folate transporter), member 1
chr4_-_30440116 0.38 ENSDART00000159935
si:dkey-199m13.5
chr2_+_4207209 0.38 ENSDART00000157903
ENSDART00000166476
GATA binding protein 6
chr13_+_233482 0.38 ENSDART00000102511
cilia and flagella associated protein 36
chr5_-_68244564 0.37 ENSDART00000169350

chr20_-_6196989 0.37 ENSDART00000013343
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr25_+_7532627 0.37 ENSDART00000187660
phosphatidylserine synthase 2
chr5_-_18962794 0.36 ENSDART00000145210
ankyrin repeat and LEM domain containing 2
chr18_-_1270220 0.36 ENSDART00000193754
UDP glucuronosyltransferase 5 family, polypeptide F1
chr6_+_59832786 0.36 ENSDART00000154985
ENSDART00000102148
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr8_+_16758304 0.36 ENSDART00000133514
ELOVL fatty acid elongase 7a
chr10_-_15854743 0.36 ENSDART00000092343
tight junction protein 2a (zona occludens 2)
chr25_+_34845469 0.36 ENSDART00000145416
transmembrane protein 231
chr17_+_44030692 0.36 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr2_+_38055529 0.36 ENSDART00000145642
si:rp71-1g18.1
chr25_+_4660639 0.35 ENSDART00000130299
DEAF1 transcription factor
chr21_+_21743599 0.35 ENSDART00000101700
polymerase (DNA-directed), delta 3, accessory subunit
chr7_+_22801465 0.35 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr15_-_684911 0.35 ENSDART00000161685
zgc:171901
chr10_+_18877362 0.35 ENSDART00000138334
protein phosphatase 2, regulatory subunit B, alpha b
chr1_+_31725154 0.35 ENSDART00000112333
ENSDART00000189801
cyclin and CBS domain divalent metal cation transport mediator 2b
chr1_-_54735441 0.34 ENSDART00000109089
cell division cycle 25 homolog d
chr11_-_23687158 0.34 ENSDART00000189599
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr8_-_37043900 0.34 ENSDART00000139567
renin binding protein
chr5_+_51248784 0.34 ENSDART00000159571
ENSDART00000189513
ENSDART00000092285
mutS homolog 3 (E. coli)
chr18_+_41560822 0.34 ENSDART00000158503
bromodomain adjacent to zinc finger domain, 1B
chr4_-_42014474 0.33 ENSDART00000193544
si:dkey-237m9.1
chr22_-_10156581 0.33 ENSDART00000168304
RanBP-type and C3HC4-type zinc finger containing 1
chr4_-_8152746 0.33 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr16_+_23531583 0.33 ENSDART00000146708
adenosine deaminase, RNA-specific
chr3_-_29891218 0.32 ENSDART00000142118
solute carrier family 25, member 39
chr7_+_34236238 0.32 ENSDART00000052474
timeless interacting protein
chr7_-_19146925 0.32 ENSDART00000142924
ENSDART00000009695
kirre like nephrin family adhesion molecule 1a
chr2_-_48255843 0.32 ENSDART00000056277
GRB10 interacting GYF protein 2
chr2_-_6292510 0.32 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr4_-_12102025 0.32 ENSDART00000048391
ENSDART00000023894
B-Raf proto-oncogene, serine/threonine kinase
chr23_+_44634187 0.31 ENSDART00000143688
si:ch73-265d7.2
chr6_-_51573975 0.31 ENSDART00000073865
retinoblastoma-like 1 (p107)
chr19_+_5135113 0.31 ENSDART00000151310
si:dkey-89b17.4
chr22_-_6651382 0.31 ENSDART00000124308
si:ch211-209l18.4
chr3_-_32180796 0.30 ENSDART00000133191
ENSDART00000055308
PIH1 domain containing 1
chr13_-_11971148 0.30 ENSDART00000066230
ENSDART00000185614
zgc:110197
chr15_+_15516612 0.30 ENSDART00000016024
tnf receptor-associated factor 4a
chr7_+_13491452 0.30 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr6_+_33885828 0.30 ENSDART00000179994
GC-rich promoter binding protein 1-like 1
chr15_+_34963316 0.30 ENSDART00000153840
si:ch73-95l15.5
chr5_+_11812089 0.30 ENSDART00000111359
F-box protein 21
chr6_-_7686594 0.29 ENSDART00000091836
ENSDART00000151697
ubinuclein 2a
chr8_+_23639124 0.29 ENSDART00000083108
5'-nucleotidase domain containing 2
chr16_+_26547152 0.29 ENSDART00000141393
protein tyrosine phosphatase, non-receptor type 3
chr18_+_45645357 0.29 ENSDART00000010256
eukaryotic translation initiation factor 3, subunit M
chr11_-_22371105 0.29 ENSDART00000146873
transmembrane protein 183A
chr3_-_29891456 0.29 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr19_+_43978814 0.28 ENSDART00000102314
naked cuticle homolog 3
chr8_+_32722842 0.28 ENSDART00000147594
hemicentin 2
chr23_+_11285662 0.28 ENSDART00000111028
cell adhesion molecule L1-like a
chr20_+_35857399 0.28 ENSDART00000102611
CD2-associated protein
chr4_+_63818718 0.28 ENSDART00000161177
si:dkey-30f3.2
chr5_-_52215926 0.28 ENSDART00000163973
ENSDART00000193602
leucyl/cystinyl aminopeptidase
chr7_-_6444011 0.27 ENSDART00000173010
zgc:112234
chr20_+_54333774 0.27 ENSDART00000144633
CLOCK-interacting pacemaker b
chr8_-_18582922 0.27 ENSDART00000123917
transmembrane protein 47
chr5_-_52216170 0.27 ENSDART00000158542
ENSDART00000192981
leucyl/cystinyl aminopeptidase
chr22_+_26703026 0.27 ENSDART00000158756
CREB binding protein a
chr4_+_16710001 0.27 ENSDART00000035899
plakophilin 2
chr7_-_67316903 0.27 ENSDART00000159408
proteasome 26S subunit, non-ATPase 7
chr9_-_2594410 0.27 ENSDART00000188306
ENSDART00000164276
sp9 transcription factor
chr15_-_47458034 0.26 ENSDART00000168527
inositol polyphosphate phosphatase-like 1a
chr2_+_22531185 0.26 ENSDART00000171959
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr25_+_36405021 0.26 ENSDART00000152801
ankyrin repeat domain 27 (VPS9 domain)
chr19_+_816208 0.26 ENSDART00000093304
nurim
chr5_-_35200590 0.26 ENSDART00000051271
FCH domain only 2
chr5_+_38886499 0.25 ENSDART00000076845
Fraser extracellular matrix complex subunit 1
chr1_+_11107688 0.25 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr10_-_76352 0.25 ENSDART00000186560
ENSDART00000144722
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr19_+_10473612 0.25 ENSDART00000125718
si:ch211-171h4.7
chr14_-_15956921 0.25 ENSDART00000190500
fms-related tyrosine kinase 4
chr16_-_40459104 0.25 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr18_+_302796 0.25 ENSDART00000157434
ENSDART00000160279
LSM14A mRNA processing body assembly factor b
chr21_+_26028947 0.25 ENSDART00000028007
SPT6 homolog, histone chaperone
chr2_-_14272083 0.25 ENSDART00000169986
Tctex1 domain containing 1
chr8_+_18010978 0.25 ENSDART00000039887
ENSDART00000144532
single stranded DNA binding protein 3b
chr9_-_41090048 0.24 ENSDART00000131681
ENSDART00000182552
asparagine synthetase domain containing 1
chr14_-_40850481 0.24 ENSDART00000173236
E74-like ETS transcription factor 1
chr19_-_10295173 0.24 ENSDART00000136697
CCR4-NOT transcription complex, subunit 3b
chr16_-_26855936 0.24 ENSDART00000167320
ENSDART00000078119
INO80 complex subunit C
chr4_-_33405483 0.24 ENSDART00000150625

chr9_+_56422517 0.24 ENSDART00000168620
G protein-coupled receptor 39
chr20_+_37300699 0.24 ENSDART00000067053
vesicle (multivesicular body) trafficking 1
chr7_+_24153070 0.24 ENSDART00000076735
low density lipoprotein receptor-related protein 10
chr5_-_72324371 0.23 ENSDART00000006380
T-box 3a
chr16_-_2390931 0.23 ENSDART00000149463
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr20_+_263056 0.23 ENSDART00000132669
tubulin, epsilon 1
chr1_-_25144439 0.23 ENSDART00000132355
F-box and WD repeat domain containing 7
chr7_+_66884291 0.23 ENSDART00000187499
SET binding factor 2
chr4_+_67318419 0.22 ENSDART00000185025
ENSDART00000185535
ENSDART00000180288
ENSDART00000192414

chr24_+_35387517 0.22 ENSDART00000058571
snail family zinc finger 2
chr4_+_44808133 0.22 ENSDART00000184430
zinc finger protein 1107
chr11_+_23933016 0.22 ENSDART00000000486
contactin 2
chr8_+_10305400 0.22 ENSDART00000172400
Pim-1 proto-oncogene, serine/threonine kinase
chr19_+_9232676 0.21 ENSDART00000136957
lysine (K)-specific methyltransferase 2Ba
chr7_-_67317119 0.21 ENSDART00000183915
proteasome 26S subunit, non-ATPase 7
chr6_+_6491013 0.21 ENSDART00000140827
B cell CLL/lymphoma 11Ab
chr10_+_15187316 0.21 ENSDART00000179732

chr1_+_44523516 0.21 ENSDART00000147702
zinc finger, DHHC-type containing 5a
chr6_+_7977611 0.20 ENSDART00000112290
paralemmin 3
chr8_+_18010568 0.20 ENSDART00000121984
single stranded DNA binding protein 3b
chr12_-_16990896 0.20 ENSDART00000152402
interferon-induced protein with tetratricopeptide repeats 12
chr10_+_36695597 0.20 ENSDART00000169015
ENSDART00000171392
RAB6A, member RAS oncogene family
chr8_-_41228530 0.20 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr9_-_24046287 0.20 ENSDART00000184313
atypical chemokine receptor 3a
chr10_-_1180314 0.20 ENSDART00000114261
bone morphogenetic protein receptor, type IBb
chr2_+_20925899 0.20 ENSDART00000099913
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr19_-_6193448 0.19 ENSDART00000151405
Ets2 repressor factor
chr2_+_16696052 0.19 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr5_+_338154 0.19 ENSDART00000191743
ring finger protein 170
chr17_-_2584423 0.19 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr22_-_34872533 0.19 ENSDART00000167176
slit homolog 1b (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of foxn1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.2 0.7 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.2 0.6 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 0.7 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.2 0.5 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.2 0.5 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.2 0.8 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.7 GO:0043111 replication fork arrest(GO:0043111)
0.1 0.4 GO:0015884 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.5 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.9 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.2 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.4 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.1 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.2 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.4 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.8 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 1.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.6 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 0.5 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 0.3 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0017145 stem cell division(GO:0017145)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.1 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:1901673 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of mitotic spindle assembly(GO:1901673) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.9 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.1 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043) regulation of heart growth(GO:0060420)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.5 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.3 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1903573 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.3 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.4 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.4 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.2 GO:1902806 regulation of cell cycle G1/S phase transition(GO:1902806)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.6 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.0 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097361 CIA complex(GO:0097361)
0.1 0.5 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.7 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0097255 R2TP complex(GO:0097255)
0.1 0.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.5 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0031464 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.4 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.3 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.1 0.6 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.0 1.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.0 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling