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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxm1

Z-value: 0.67

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Transcription factors associated with foxm1

Gene Symbol Gene ID Gene Info
ENSDARG00000003200 forkhead box M1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxm1dr11_v1_chr4_-_5831522_58315220.699.8e-04Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_47822597 2.02 ENSDART00000193236
ENSDART00000161391

chr7_-_41554047 1.79 ENSDART00000174144
plexin domain containing 2
chr4_+_15944245 1.65 ENSDART00000134594
si:dkey-117n7.3
chr7_+_15736230 1.37 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr14_-_41478265 1.30 ENSDART00000149886
ENSDART00000016002
tetraspanin 7
chr14_+_22114918 1.30 ENSDART00000166610
thioredoxin-related transmembrane protein 2a
chr7_+_39401388 1.25 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr20_+_25904199 1.14 ENSDART00000016864
solute carrier family 35, member F6
chr22_-_17606575 1.14 ENSDART00000183951
glutathione peroxidase 4a
chr17_+_23975762 1.11 ENSDART00000155941
exportin 1 (CRM1 homolog, yeast) b
chr11_-_18107447 1.02 ENSDART00000187376
glutamine-rich 1
chr4_+_5196469 1.01 ENSDART00000067386
RAD51 associated protein 1
chr2_+_37838259 1.00 ENSDART00000136796
poly (ADP-ribose) polymerase 2
chr14_-_4177311 0.96 ENSDART00000128129
si:dkey-185e18.7
chr10_-_35257458 0.95 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr16_+_40131473 0.91 ENSDART00000155421
ENSDART00000134732
ENSDART00000138699
centromere protein W
si:ch211-195p4.4
chr1_-_18585046 0.91 ENSDART00000147228
family with sequence similarity 114, member A1
chr2_+_33926911 0.90 ENSDART00000109849
ENSDART00000135884
kinesin family member 2C
chr15_+_23534126 0.89 ENSDART00000152320
si:dkey-182i3.10
chr16_-_32303835 0.88 ENSDART00000191408
MMS22-like, DNA repair protein
chr24_+_5893134 0.88 ENSDART00000077941
microtubule associated serine/threonine kinase-like
chr11_-_18017918 0.87 ENSDART00000040171
glutamine-rich 1
chr6_-_40922971 0.86 ENSDART00000155363
SFI1 centrin binding protein
chr17_+_8799661 0.82 ENSDART00000105326
tonsoku-like, DNA repair protein
chr14_-_22015232 0.81 ENSDART00000137795
structure specific recognition protein 1a
chr2_-_44777592 0.80 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr9_+_21259820 0.79 ENSDART00000137024
ENSDART00000132324
spindle and kinetochore associated complex subunit 3
chr13_+_5978809 0.78 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr15_-_44052927 0.78 ENSDART00000166209
wu:fb44b02
chr22_+_1526040 0.77 ENSDART00000164089
ENSDART00000159126
si:ch211-255f4.6
chr14_-_52480661 0.76 ENSDART00000158353
exosome component 3
chr2_-_14793343 0.76 ENSDART00000132264
si:ch73-366i20.1
chr20_-_39596338 0.76 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr11_-_18017287 0.75 ENSDART00000155443
glutamine-rich 1
chr2_+_25840463 0.75 ENSDART00000125178
eukaryotic translation initiation factor 5A2
chr11_-_28614608 0.75 ENSDART00000065853
dehydrogenase/reductase (SDR family) member 3b
chr7_+_24023653 0.75 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr17_+_32622933 0.74 ENSDART00000077418
cathepsin Ba
chr17_-_11439815 0.73 ENSDART00000130105
proteasome subunit alpha 3
chr14_-_30905963 0.72 ENSDART00000183543
ENSDART00000186441
si:ch211-126c2.4
chr17_+_45639247 0.72 ENSDART00000153669
valosin containing protein lysine (K) methyltransferase
chr2_-_37837472 0.72 ENSDART00000165347
methyltransferase like 17
chr9_+_23770666 0.70 ENSDART00000182493
si:ch211-219a4.3
chr14_+_22498757 0.69 ENSDART00000021657
SMYD family member 5
chr6_-_14040136 0.69 ENSDART00000065361
ENSDART00000179765
ets variant 5b
chr4_+_14981854 0.68 ENSDART00000067046
cation/H+ exchanger protein 1
chr1_+_38362412 0.68 ENSDART00000075086
centrosomal protein 44
chr17_-_4245902 0.67 ENSDART00000151851
growth differentiation factor 3
chr8_-_22558773 0.67 ENSDART00000074309
porcupine O-acyltransferase like
chr14_-_41388178 0.66 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr3_-_54607166 0.66 ENSDART00000021977
DNA (cytosine-5-)-methyltransferase 1
chr13_+_26703922 0.64 ENSDART00000020946
Fanconi anemia, complementation group L
chr10_+_19017146 0.64 ENSDART00000038674
transmembrane protein 230a
chr13_+_10023256 0.64 ENSDART00000110035
S1 RNA binding domain 1
chr16_-_30570161 0.64 ENSDART00000184045
ENSDART00000191040
lamin A
chr9_+_22780901 0.62 ENSDART00000110992
ENSDART00000143972
replication timing regulatory factor 1
chr8_+_32719930 0.62 ENSDART00000145362
hemicentin 2
chr18_+_6857071 0.62 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr7_+_30282389 0.62 ENSDART00000108782
RNA polymerase II subunit M
chr2_-_29996036 0.61 ENSDART00000020792
canopy1
chr22_+_9239831 0.61 ENSDART00000133720
si:ch211-250k18.5
chr14_-_8453192 0.61 ENSDART00000136947
eukaryotic translation initiation factor 1A domain containing
chr11_-_36474306 0.61 ENSDART00000170678
ENSDART00000123591
ubiquitin specific peptidase 48
chr13_+_33298338 0.61 ENSDART00000131892
ENSDART00000143895
IQ motif containing C
chr14_-_38826739 0.60 ENSDART00000187633
spindle apparatus coiled-coil protein 1
chr7_+_1505507 0.60 ENSDART00000161015
NOP10 ribonucleoprotein homolog (yeast)
chr6_-_22064158 0.59 ENSDART00000153585
cilia and flagella associated protein 100
chr16_-_32006737 0.59 ENSDART00000184813
ENSDART00000179827
glutathione S-transferase kappa 4
chr1_-_23268013 0.59 ENSDART00000146575
replication factor C (activator 1) 1
chr15_+_37589698 0.59 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr3_+_60589157 0.59 ENSDART00000165367
methyltransferase like 23
chr13_+_11828516 0.59 ENSDART00000110141
suppressor of fused homolog (Drosophila)
chr8_-_18211605 0.58 ENSDART00000114177

chr1_+_19538299 0.58 ENSDART00000109416
structural maintenance of chromosomes 2
chr16_+_53125918 0.57 ENSDART00000102170

chr14_+_52481288 0.57 ENSDART00000169164
ENSDART00000159297
transcription elongation regulator 1a (CA150)
chr11_-_33618612 0.57 ENSDART00000033980
LIM and senescent cell antigen-like domains 1
chr12_+_19191787 0.57 ENSDART00000152892
solute carrier family 16 (monocarboxylate transporter), member 8
chr23_+_39611688 0.57 ENSDART00000034690
OTU deubiquitinase 3
chr5_+_29726428 0.57 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr12_+_17154655 0.57 ENSDART00000028003
ankyrin repeat domain 22
chr22_-_9934854 0.56 ENSDART00000136404
si:dkey-253d23.11
chr3_+_37112693 0.56 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
PSMC3 interacting protein
chr13_+_2894536 0.55 ENSDART00000183678

chr10_+_22891126 0.55 ENSDART00000057291
arrestin, beta 2a
chr4_-_39110934 0.55 ENSDART00000185041
si:dkey-122c11.8
chr7_-_6444011 0.53 ENSDART00000173010
zgc:112234
chr15_-_23784600 0.53 ENSDART00000059354
RAD1 homolog (S. pombe)
chr22_-_8692305 0.53 ENSDART00000181602

chr5_-_54672763 0.52 ENSDART00000159009
sperm associated antigen 8
chr14_+_21686207 0.52 ENSDART00000034438
RAN, member RAS oncogene family
chr18_-_20458412 0.52 ENSDART00000012241
kinesin family member 23
chr14_-_16082806 0.52 ENSDART00000165656
MAX dimerization protein 3
chr23_+_13928346 0.52 ENSDART00000155326
si:dkey-90a13.10
chr9_+_33216945 0.51 ENSDART00000134029
si:ch211-125e6.12
chr10_-_42237304 0.51 ENSDART00000140341
transcription factor 7 like 1a
chr11_-_22369303 0.51 ENSDART00000163450
transmembrane protein 183A
chr19_+_7759354 0.50 ENSDART00000151400
ubiquitin associated protein 2-like
chr6_+_16736871 0.49 ENSDART00000155471
Pim proto-oncogene, serine/threonine kinase, related 12
chr1_-_28861226 0.49 ENSDART00000075502
translocase of inner mitochondrial membrane domain containing 1
chr8_-_26033176 0.49 ENSDART00000184533

chr18_-_20458840 0.48 ENSDART00000177125
kinesin family member 23
chr10_-_35051691 0.48 ENSDART00000108670
ENSDART00000190711
SPT20 homolog, SAGA complex component
chr4_+_38103421 0.48 ENSDART00000164164
zinc finger protein 1016
chr15_-_23692359 0.48 ENSDART00000141618
excision repair cross-complementation group 2
chr7_+_26716321 0.47 ENSDART00000189750
CD82 molecule a
chr4_+_59234719 0.47 ENSDART00000170724
ENSDART00000192143
ENSDART00000109914
zinc finger protein 1086
chr15_-_18232712 0.47 ENSDART00000081199
wu:fj20b03
chr25_+_3868438 0.46 ENSDART00000156438
transmembrane protein 138
chr17_-_42213822 0.46 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr14_+_31865099 0.46 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr3_-_49514874 0.46 ENSDART00000167179
anti-silencing function 1Ba histone chaperone
chr1_-_55166511 0.46 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr17_-_32621103 0.45 ENSDART00000155321
XK related 5b
chr21_-_13856689 0.44 ENSDART00000102197
family with sequence similarity 129, member Ba
chr22_+_31059919 0.44 ENSDART00000077063
SEC13 homolog, nuclear pore and COPII coat complex component
chr4_+_69510337 0.44 ENSDART00000165995
zinc finger protein 1025
chr21_+_3796620 0.44 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr4_+_65127317 0.44 ENSDART00000166475
zinc finger protein 1126
chr17_+_8542203 0.44 ENSDART00000158873

chr21_-_25565392 0.44 ENSDART00000144917
ENSDART00000180102
si:dkey-17e16.10
chr5_+_50898849 0.44 ENSDART00000083317
arylsulfatase family, member K
chr19_-_10324182 0.43 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
U2 small nuclear RNA auxiliary factor 2b
chr13_+_44857087 0.43 ENSDART00000017770
zinc finger and BTB domain containing 8 opposite strand
chr7_-_51102479 0.42 ENSDART00000174023
collagen, type IV, alpha 6
chr10_+_35257651 0.42 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr7_-_13906409 0.42 ENSDART00000062257
solute carrier family 39 (zinc transporter), member 1
chr21_-_23046606 0.42 ENSDART00000016167
zw10 kinetochore protein
chr7_+_60359347 0.42 ENSDART00000145201
ENSDART00000039827
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr22_-_22301672 0.41 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr7_+_55950229 0.41 ENSDART00000082780
acyl-CoA synthetase family member 3
chr23_+_30985530 0.41 ENSDART00000142953
si:ch211-197l9.2
chr12_-_33558879 0.41 ENSDART00000161167
mbt domain containing 1
chr5_-_24333684 0.40 ENSDART00000051553
zinc finger protein 703
chr25_-_22187397 0.40 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr6_+_16870004 0.40 ENSDART00000154794
Pim proto-oncogene, serine/threonine kinase, related 21
chr17_-_25630822 0.40 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr3_-_60589292 0.39 ENSDART00000157822
jumonji domain containing 6
chr15_+_23784842 0.39 ENSDART00000192889
ENSDART00000138375
intraflagellar transport 20 homolog (Chlamydomonas)
chr1_+_52137528 0.39 ENSDART00000007079
ENSDART00000074265
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr16_+_25068576 0.38 ENSDART00000125838
im:7147486
chr7_+_38811800 0.38 ENSDART00000052322
zgc:110699
chr23_+_1078072 0.38 ENSDART00000159263
ENSDART00000053527
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr19_-_46018152 0.38 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr6_+_35362225 0.37 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr3_-_29891218 0.37 ENSDART00000142118
solute carrier family 25, member 39
chr15_-_14210382 0.37 ENSDART00000179599

chr15_-_37589600 0.37 ENSDART00000154641
proline and serine rich 3
chr19_+_18627100 0.36 ENSDART00000167245
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_+_40922572 0.36 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr4_-_6373735 0.36 ENSDART00000140100
si:ch73-156e19.1
chr6_+_27090800 0.36 ENSDART00000121558
autophagy related 4B, cysteine peptidase
chr9_-_38036984 0.36 ENSDART00000134574
3-hydroxyacyl-CoA dehydratase 2
chr18_-_15932704 0.36 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr15_+_1653779 0.35 ENSDART00000021299
NMD3 ribosome export adaptor
chr2_-_37803614 0.35 ENSDART00000154124
nuclear factor of activated T cells 4
chr8_+_23147218 0.35 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr16_-_35952789 0.34 ENSDART00000180118
eva-1 homolog Ba (C. elegans)
chr6_-_54444929 0.34 ENSDART00000154121
Sys1 golgi trafficking protein
chr22_+_17606863 0.33 ENSDART00000035670
polymerase (RNA) II (DNA directed) polypeptide E, b
chr9_-_38368138 0.33 ENSDART00000059574
coiled-coil domain containing 93
chr13_+_33655404 0.33 ENSDART00000023379
mitochondrial genome maintenance exonuclease 1
chr6_+_56147812 0.33 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_+_39099380 0.32 ENSDART00000166657
BMP2 inducible kinase
chr25_+_27873671 0.32 ENSDART00000088817
IQ motif and ubiquitin domain containing
chr21_+_40685895 0.31 ENSDART00000017709
coiled-coil domain containing 82
chr5_-_16351306 0.30 ENSDART00000168643

chr25_+_27873836 0.30 ENSDART00000163801
IQ motif and ubiquitin domain containing
chr12_+_28888975 0.30 ENSDART00000076362
phosphorylase kinase, gamma 2 (testis)
chr6_+_16949735 0.30 ENSDART00000155342
Pim proto-oncogene, serine/threonine kinase, related 13
chr20_+_6663544 0.29 ENSDART00000135390
tensin 3, tandem duplicate 2
chr6_+_28018390 0.29 ENSDART00000123324
ENSDART00000150915
Sin3A-associated protein a
chr4_-_39111612 0.28 ENSDART00000150394
si:dkey-122c11.8
chr2_-_59231017 0.28 ENSDART00000143980
ENSDART00000184190
finTRIM family, member 29
chr11_-_11336986 0.28 ENSDART00000016677
zgc:77929
chr14_-_52433292 0.28 ENSDART00000164272
RE1-silencing transcription factor
chr7_+_17255705 0.28 ENSDART00000053357
ENSDART00000167849
ENSDART00000165833
novel immune-type receptor 9
si:ch73-46n24.1
chr3_-_37082618 0.28 ENSDART00000026701
ENSDART00000110716
tubulin, gamma 1
chr3_-_37758487 0.28 ENSDART00000150938
si:dkey-260c8.6
chr6_-_16948040 0.27 ENSDART00000156433
Pim proto-oncogene, serine/threonine kinase, related 30
chr15_-_1001177 0.27 ENSDART00000160730
zgc:162936
chr8_-_21071476 0.27 ENSDART00000184184
ENSDART00000100288
zgc:112962
chr7_-_19638319 0.26 ENSDART00000163686
si:ch211-212k18.4
chr6_+_11397269 0.26 ENSDART00000114260
SUMO1/sentrin/SMT3 specific peptidase 2
chr17_+_46818521 0.26 ENSDART00000156022
Pim proto-oncogene, serine/threonine kinase, related 14
chr1_-_23268569 0.26 ENSDART00000143948
replication factor C (activator 1) 1
chr5_+_34982318 0.25 ENSDART00000160504
ankyrin repeat, family A (RFXANK-like), 2
chr7_-_4125021 0.25 ENSDART00000167182
ENSDART00000173696
zgc:55733
chr9_-_55772937 0.25 ENSDART00000159192
A kinase (PRKA) anchor protein 17A
chr19_-_7832439 0.24 ENSDART00000104703
ENSDART00000132336
zinc finger protein 687b
chr7_-_19642417 0.24 ENSDART00000160936
si:ch211-212k18.4
chr24_-_20915050 0.24 ENSDART00000133763
si:ch211-161h7.5
chr14_+_44804326 0.24 ENSDART00000079866
ENSDART00000172974
solute carrier family 30 (zinc transporter), member 9
chr13_+_31550185 0.24 ENSDART00000127843
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr13_+_24679674 0.24 ENSDART00000033090
ENSDART00000139854
zgc:66426
chr9_+_27354414 0.23 ENSDART00000163804
toll-like receptor 20, tandem duplicate 2
chr10_+_6121558 0.23 ENSDART00000166799
ENSDART00000157947
talin 1
chr18_+_27001115 0.23 ENSDART00000133547
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr20_-_26383368 0.23 ENSDART00000024518
ENSDART00000087844
estrogen receptor 1
chr14_+_23687678 0.23 ENSDART00000002469
heat shock protein 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0071034 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.3 0.8 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.2 0.7 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 0.5 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:0046823 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.5 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.7 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.5 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 1.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.5 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.4 GO:0045601 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.1 1.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.2 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.7 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.6 GO:0090342 regulation of cell aging(GO:0090342)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 1.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.4 GO:0035790 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.3 GO:1903430 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.1 0.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.6 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 1.7 GO:0031297 replication fork processing(GO:0031297)
0.1 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.2 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.2 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.9 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.6 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.7 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 0.5 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:1903429 regulation of cell maturation(GO:1903429)
0.0 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979) limb morphogenesis(GO:0035108)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.7 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0031650 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.3 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.0 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.9 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.3 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.2 GO:0030104 water homeostasis(GO:0030104)
0.0 0.3 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.8 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.8 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.5 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.6 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0035101 FACT complex(GO:0035101)
0.2 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.6 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.4 GO:0000938 GARP complex(GO:0000938)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.2 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.5 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 0.7 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.4 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 2.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 4.2 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME KINESINS Genes involved in Kinesins
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress