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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxi1+foxi2+foxi3a+foxi3b

Z-value: 1.08

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Transcription factors associated with foxi1+foxi2+foxi3a+foxi3b

Gene Symbol Gene ID Gene Info
ENSDARG00000009550 forkhead box I3b
ENSDARG00000055926 forkhead box I3a
ENSDARG00000069715 forkhead box I2
ENSDARG00000104566 forkhead box i1
ENSDARG00000112022 forkhead box I3b
ENSDARG00000112303 forkhead box I3b
ENSDARG00000116791 forkhead box I2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxi1dr11_v1_chr12_-_43664682_43664682-0.901.0e-07Click!
foxi3adr11_v1_chr21_+_30351256_30351256-0.886.6e-07Click!
foxi2dr11_v1_chr13_+_13578552_13578552-0.812.3e-05Click!
foxi3bdr11_v1_chr14_+_34514336_34514336-0.522.3e-02Click!

Activity profile of foxi1+foxi2+foxi3a+foxi3b motif

Sorted Z-values of foxi1+foxi2+foxi3a+foxi3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_37837245 4.45 ENSDART00000171617
ependymin
chr24_-_4765740 3.66 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr5_+_51079504 3.62 ENSDART00000097466
family with sequence similarity 169, member Aa
chr22_+_31821815 3.49 ENSDART00000159825
dedicator of cytokinesis 3
chr16_+_14588141 3.40 ENSDART00000140469
ENSDART00000059984
ENSDART00000167411
ENSDART00000133566
DEP domain containing MTOR-interacting protein
chr6_-_35446110 3.37 ENSDART00000058773
regulator of G protein signaling 16
chr9_-_44948488 3.10 ENSDART00000059228
villin 1
chr8_-_21372446 2.98 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr18_-_21097663 2.96 ENSDART00000060196
alanyl (membrane) aminopeptidase a
chr20_+_30445971 2.94 ENSDART00000153150
myelin transcription factor 1-like, a
chr15_+_36457888 2.89 ENSDART00000155100
si:dkey-262k9.2
chr1_-_43915423 2.88 ENSDART00000181915
ENSDART00000113673
secretory calcium-binding phosphoprotein 5
chr19_-_27261102 2.80 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr17_-_11417904 2.73 ENSDART00000103228
AT rich interactive domain 4A (RBP1-like)
chr6_-_13783604 2.64 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr20_-_45709990 2.53 ENSDART00000027482
glycerophosphocholine phosphodiesterase 1
chr11_+_6422374 2.50 ENSDART00000183148

chr7_+_38510197 2.46 ENSDART00000173468
ENSDART00000100479
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr10_-_24343507 2.42 ENSDART00000002974
phosphatidylinositol transfer protein, alpha b
chr22_+_20720808 2.41 ENSDART00000171321
si:dkey-211f22.5
chr5_-_33215261 2.40 ENSDART00000097935
ENSDART00000134777
si:dkey-226m8.10
chr5_-_37935607 2.39 ENSDART00000141233
ENSDART00000084868
ENSDART00000125857
sodium channel, voltage-gated, type IV, beta b
chr25_+_14087045 2.37 ENSDART00000155770
actin, alpha, cardiac muscle 1c
chr14_-_2352384 2.36 ENSDART00000170666
si:ch73-233f7.7
chr17_+_20605013 2.33 ENSDART00000156878
si:ch73-288o11.5
chr20_+_42565049 2.24 ENSDART00000061101
insulin-like growth factor 2 receptor
chr4_-_18436899 2.11 ENSDART00000141671
suppressor of cytokine signaling 2
chr8_-_14049404 2.10 ENSDART00000093117
ATPase plasma membrane Ca2+ transporting 3a
chr5_-_23362602 2.08 ENSDART00000137120
glutamate receptor, ionotropic, AMPA 3a
chr17_-_11417551 2.07 ENSDART00000128291
AT rich interactive domain 4A (RBP1-like)
chr14_-_2348917 2.05 ENSDART00000159004
si:ch73-233f7.8
chr6_-_49873020 2.00 ENSDART00000148511
GNAS complex locus
chr5_+_37068223 1.95 ENSDART00000164279
si:dkeyp-110c7.4
chr10_-_14929392 1.92 ENSDART00000137430
SMAD family member 2
chr16_+_5612547 1.91 ENSDART00000140226
ENSDART00000189352
si:dkey-283b15.4
chr17_+_44756247 1.89 ENSDART00000153773
CLOCK-interacting pacemaker a
chr12_-_31422433 1.87 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vesicle transport through interaction with t-SNAREs 1A
chr16_-_17207754 1.82 ENSDART00000063804
wu:fj39g12
chr5_+_36768674 1.79 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr6_-_10780698 1.77 ENSDART00000151714
G protein-coupled receptor 155b
chr1_+_45839927 1.71 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr19_+_20724347 1.68 ENSDART00000090757
K(lysine) acetyltransferase 2B
chr23_+_17220986 1.64 ENSDART00000054761
nucleolar protein 4-like b
chr4_+_8797197 1.59 ENSDART00000158671
sulfotransferase family 4A, member 1
chr10_+_1638876 1.58 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr10_+_26972755 1.56 ENSDART00000042162
transmembrane 7 superfamily member 2
chr1_-_46862190 1.52 ENSDART00000145167
1-acylglycerol-3-phosphate O-acyltransferase 3
chr9_-_12574473 1.52 ENSDART00000191372
ENSDART00000193667
insulin-like growth factor 2 mRNA binding protein 2a
chr10_+_36650222 1.50 ENSDART00000126963
uncoupling protein 3
chr13_+_37653851 1.50 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr19_+_1510971 1.48 ENSDART00000157721
solute carrier family 45 member 4
chr18_+_12147971 1.48 ENSDART00000162067
ENSDART00000168386
FYVE, RhoGEF and PH domain containing 4a
chr16_-_29334672 1.46 ENSDART00000162835
brevican
chr10_-_43404027 1.43 ENSDART00000086227
EGF-like repeats and discoidin I-like domains 3b
chr19_-_44091405 1.42 ENSDART00000132800
RAD21 cohesin complex component b
chr11_-_17713987 1.40 ENSDART00000090401
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr19_-_9503473 1.36 ENSDART00000091615
intermediate filament family orphan 1a
chr21_+_31434251 1.35 ENSDART00000040740
ENSDART00000130157
si:ch211-12m10.1
si:ch211-166i24.1
chr13_-_29505604 1.34 ENSDART00000110005
cadherin-related family member 1a
chr2_-_57110477 1.34 ENSDART00000181132
solute carrier family 25, member 42
chr9_-_23253870 1.34 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr4_+_7391400 1.33 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr7_-_33868903 1.33 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr14_-_18671334 1.30 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr11_+_30817943 1.29 ENSDART00000150130
ENSDART00000159997
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr9_+_2762270 1.28 ENSDART00000123342
ENSDART00000001795
ENSDART00000177563
sp3a transcription factor
chr1_-_22757145 1.27 ENSDART00000134719
prominin 1 b
chr6_-_52796212 1.26 ENSDART00000154133
recombination signal binding protein for immunoglobulin kappa J region-like
chr1_-_30039331 1.22 ENSDART00000086935
ENSDART00000143800
zgc:153256
chr18_+_37015185 1.21 ENSDART00000191305
signal-induced proliferation-associated 1 like 3
chr13_+_27316934 1.19 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr15_-_4314042 1.19 ENSDART00000173311
ENSDART00000170562
si:ch211-117a13.2
chr20_-_8304271 1.17 ENSDART00000179057
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr21_-_21148623 1.16 ENSDART00000184364
ankyrin 1, erythrocytic b
chr24_-_2312868 1.16 ENSDART00000140125
ENSDART00000138432
cullin 2
chr14_+_15231097 1.14 ENSDART00000172430
si:dkey-203a12.3
chr13_-_29505946 1.14 ENSDART00000026679
cadherin-related family member 1a
chr21_-_42202792 1.10 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr1_+_6817292 1.08 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr10_+_21584195 1.07 ENSDART00000100599
protocadherin 1 alpha 3
chr22_-_14367966 1.07 ENSDART00000188796
low density lipoprotein receptor-related protein 1Ba
chr2_+_5948534 1.06 ENSDART00000124324
ENSDART00000176461
solute carrier family 1 (glutamate transporter), member 7a
chr5_-_63286077 1.06 ENSDART00000131274
tubulin folding cofactor E-like b
chr7_-_52842605 1.06 ENSDART00000083002
microtubule-associated protein 1Aa
chr6_+_4255319 1.05 ENSDART00000170351
neurobeachin-like 1
chr10_+_17850934 1.04 ENSDART00000113666
ENSDART00000145936
PHD finger protein 24
chr3_+_20012891 1.04 ENSDART00000078974
transmembrane and ubiquitin-like domain containing 2
chr17_-_50220228 1.03 ENSDART00000058707
Jun dimerization protein 2a
chr8_+_8643901 1.03 ENSDART00000142076
ENSDART00000075624
ubiquitin specific peptidase 11
chr2_-_42492201 1.03 ENSDART00000180762
ENSDART00000009093
extended synaptotagmin-like protein 2a
chr3_+_45778810 1.01 ENSDART00000003338
ENSDART00000155409
unkempt family zinc finger-like
chr21_+_4116437 0.98 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr6_-_59563597 0.98 ENSDART00000166311
inhibin beta E subunit
chr24_-_17444067 0.95 ENSDART00000155843
contactin associated protein like 2a
chr22_+_6905210 0.94 ENSDART00000167530

chr2_-_12243213 0.93 ENSDART00000113081
G protein-coupled receptor 158b
chr3_-_24456451 0.92 ENSDART00000024480
ENSDART00000156814
BAI1-associated protein 2-like 2a
chr4_+_7391110 0.90 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr2_-_37043905 0.90 ENSDART00000056514
guanine nucleotide binding protein (G protein), gamma 7
chr15_+_28940352 0.90 ENSDART00000154085
gastric inhibitory polypeptide receptor
chr6_-_39167732 0.90 ENSDART00000153626
apolipoprotein F
chr12_+_5081759 0.87 ENSDART00000164178
proline-rich transmembrane protein 2
chr5_-_2676783 0.87 ENSDART00000159661

chr6_+_39222598 0.86 ENSDART00000154991
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr23_-_42810664 0.86 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr1_+_55752593 0.84 ENSDART00000108838
ENSDART00000134770
trans-2,3-enoyl-CoA reductase b
chr16_+_29558530 0.83 ENSDART00000088146
endosulfine alpha b
chr5_-_4931266 0.81 ENSDART00000067600
zinc finger and BTB domain containing 43
chr22_+_23359369 0.80 ENSDART00000170886
DENN/MADD domain containing 1B
chr17_-_38778826 0.80 ENSDART00000168182
ENSDART00000124041
ENSDART00000136921
D-glutamate cyclase
chr14_+_32926385 0.79 ENSDART00000139159
ligand of numb-protein X 2b
chr14_-_21219659 0.78 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr13_+_2442841 0.78 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
ARFGEF family member 3
chr22_-_28777374 0.77 ENSDART00000188206
si:dkeyp-34c12.1
chr6_+_54239625 0.76 ENSDART00000149542
protein kinase C and casein kinase substrate in neurons 1b
chr3_-_2623176 0.76 ENSDART00000179792
ENSDART00000123512
si:dkey-217f16.6
chr15_-_18432673 0.76 ENSDART00000146853
neural cell adhesion molecule 1b
chr4_-_14926637 0.76 ENSDART00000110199
PR domain containing 4
chr20_-_42702832 0.75 ENSDART00000134689
ENSDART00000045816
plasminogen
chr22_+_18469004 0.75 ENSDART00000061430
cartilage intermediate layer protein 2
chr7_+_13995792 0.73 ENSDART00000091470
furin (paired basic amino acid cleaving enzyme) a
chr4_-_6567355 0.73 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr12_+_13404784 0.71 ENSDART00000167977
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr2_-_38035235 0.71 ENSDART00000075904
cerebellin 5
chr20_+_52546186 0.71 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr15_-_20933574 0.71 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
ubiquitin specific peptidase 2a
chr10_+_29138021 0.70 ENSDART00000025227
ENSDART00000123033
ENSDART00000034242
phosphatidylinositol binding clathrin assembly protein a
chr18_+_41560822 0.69 ENSDART00000158503
bromodomain adjacent to zinc finger domain, 1B
chr19_-_45650994 0.69 ENSDART00000163504
trichorhinophalangeal syndrome I
chr17_-_27382826 0.69 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
chr7_+_13830052 0.69 ENSDART00000191360
abhydrolase domain containing 2a
chr10_+_34315719 0.68 ENSDART00000135303
StAR-related lipid transfer (START) domain containing 13a
chr11_+_33628104 0.68 ENSDART00000165318
thrombospondin, type I, domain containing 7Bb
chr3_-_56871330 0.66 ENSDART00000014103
zgc:112148
chr2_-_31798717 0.65 ENSDART00000170880
reticulophagy regulator 1
chr10_+_26973063 0.64 ENSDART00000143162
ENSDART00000186210
transmembrane 7 superfamily member 2
chr1_-_54191626 0.64 ENSDART00000062941
nth-like DNA glycosylase 1
chr15_+_42431198 0.63 ENSDART00000189951
ENSDART00000089694
T cell lymphoma invasion and metastasis 1b
chr8_+_10862353 0.63 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr7_+_42206847 0.62 ENSDART00000149250
phosphorylase kinase, beta
chr18_-_25855263 0.60 ENSDART00000042074
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr10_-_17501528 0.60 ENSDART00000144847
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr17_+_8324345 0.60 ENSDART00000172443
CDC42 binding protein kinase alpha (DMPK-like) a
chr11_+_34523132 0.60 ENSDART00000192257
zinc finger, matrin-type 3
chr3_-_55537096 0.59 ENSDART00000123544
ENSDART00000188752
testis expressed 2
chr3_-_30384353 0.59 ENSDART00000186832
leucine rich repeat containing 4Ba
chr7_-_52334429 0.58 ENSDART00000187372

chr16_+_18535618 0.57 ENSDART00000021596
retinoid x receptor, beta b
chr7_-_20836625 0.57 ENSDART00000192566
claudin 15a
chr17_+_50261603 0.56 ENSDART00000154503
ENSDART00000154467
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr20_-_14875308 0.56 ENSDART00000141290
dynamin 3a
chr20_-_45062514 0.56 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr18_-_26126258 0.55 ENSDART00000145875
ankyrin repeat domain 34C
chr8_-_31701157 0.54 ENSDART00000141799
F-box protein 4
chr17_+_5351922 0.54 ENSDART00000105394
runt-related transcription factor 2a
chr8_-_8446668 0.53 ENSDART00000132700
cyclin-dependent kinase 16
chr1_+_51191049 0.52 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr7_+_22637515 0.52 ENSDART00000158698
si:dkey-112a7.5
chr21_+_12010505 0.52 ENSDART00000123522
aquaporin 7
chr14_+_35023923 0.52 ENSDART00000172171
early B cell factor 3a
chr4_-_14926106 0.50 ENSDART00000147629
PR domain containing 4
chr10_+_21730585 0.50 ENSDART00000188576
protocadherin 1 gamma 22
chr14_+_15331486 0.50 ENSDART00000172077
ENSDART00000183370
ENSDART00000182467
si:dkey-203a12.4
si:dkey-203a12.5
chr9_-_710896 0.49 ENSDART00000180478
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr4_-_149334 0.49 ENSDART00000163280
TANK-binding kinase 1
chr14_-_21218891 0.49 ENSDART00000158294
protein phosphatase 2, regulatory subunit B, gamma b
chr21_-_33995213 0.48 ENSDART00000140184
si:ch211-51e8.2
chr7_+_16033923 0.47 ENSDART00000161669
ENSDART00000114062
inner mitochondrial membrane peptidase subunit 1
chr14_-_33177935 0.47 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr25_+_6451038 0.46 ENSDART00000009971
sorting nexin 33
chr20_-_26042070 0.45 ENSDART00000140255
si:dkey-12h9.6
chr4_+_6833735 0.45 ENSDART00000136355
dedicator of cytokinesis 4b
chr17_-_33415740 0.43 ENSDART00000135218
coiled-coil domain containing 28A
chr18_+_16192083 0.42 ENSDART00000133042
leucine-rich repeats and IQ motif containing 1
chr16_+_38820486 0.42 ENSDART00000131866
thyrotropin-releasing hormone receptor a
chr1_+_31674297 0.42 ENSDART00000044214
WW domain binding protein 1-like b
chr8_-_18316482 0.41 ENSDART00000190156
ring finger protein 220b
chr3_-_39627412 0.40 ENSDART00000123292
si:dkey-27o4.1
chr25_-_11088839 0.40 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr4_-_12997587 0.39 ENSDART00000140532
si:dkey-6a5.3
chr23_+_33383583 0.39 ENSDART00000114423
Rap guanine nucleotide exchange factor (GEF) 3
chr18_+_41561285 0.37 ENSDART00000169621
bromodomain adjacent to zinc finger domain, 1B
chr17_+_25856671 0.37 ENSDART00000064817
WAPL cohesin release factor a
chr6_-_39218609 0.37 ENSDART00000133305
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr23_-_26652273 0.37 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr12_+_13405445 0.36 ENSDART00000089042
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr1_-_31856622 0.35 ENSDART00000065125
5'-nucleotidase, cytosolic IIb
chr9_-_34974416 0.35 ENSDART00000077790
zgc:172067
chr15_+_25681044 0.33 ENSDART00000077853
hypermethylated in cancer 1
chr12_+_30234209 0.33 ENSDART00000102081
actin filament associated protein 1-like 2
chr7_+_52766211 0.33 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr15_+_26940569 0.33 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr25_-_8055229 0.33 ENSDART00000003252
dehydrogenase E1 and transketolase domain containing 1
chr21_-_33995710 0.31 ENSDART00000100508
ENSDART00000179622
early B cell factor 1b
chr9_+_24088062 0.31 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr11_+_21586335 0.31 ENSDART00000091182
zgc:101564
chr17_-_2685026 0.30 ENSDART00000191014
ENSDART00000179309
protein tyrosine phosphatase, non-receptor type 21
chr18_+_27077853 0.30 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr8_+_12930216 0.29 ENSDART00000115405
zgc:103670
chr7_+_49800849 0.29 ENSDART00000164838
ENSDART00000187888
si:ch211-102l7.3

Network of associatons between targets according to the STRING database.

First level regulatory network of foxi1+foxi2+foxi3a+foxi3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.7 2.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.6 1.7 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.5 1.9 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.4 1.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 2.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.3 1.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 2.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.2 1.3 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.2 0.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 1.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.0 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 1.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 0.6 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 1.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 1.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.3 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 2.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 3.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 2.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.7 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 3.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 2.0 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.6 GO:0051923 sulfation(GO:0051923)
0.1 0.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 1.1 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.8 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0045471 response to ethanol(GO:0045471)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 2.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 2.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 2.2 GO:0007041 lysosomal transport(GO:0007041)
0.0 2.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 3.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 4.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.8 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 1.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 6.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.5 GO:0051028 mRNA transport(GO:0051028)
0.0 2.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.8 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.9 GO:0008203 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.7 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.6 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 0.0 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0032433 filopodium tip(GO:0032433)
0.4 2.8 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.3 2.4 GO:0016586 RSC complex(GO:0016586)
0.2 1.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.3 GO:0071914 prominosome(GO:0071914)
0.1 1.0 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.7 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.1 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 3.5 GO:0005764 lysosome(GO:0005764)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.6 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 4.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.4 1.3 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.4 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 2.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 2.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 1.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 0.6 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.2 1.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 0.9 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 2.2 GO:0005537 mannose binding(GO:0005537)
0.2 1.1 GO:0035173 histone kinase activity(GO:0035173)
0.1 2.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0008126 acetylesterase activity(GO:0008126)
0.1 1.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0030507 spectrin binding(GO:0030507)
0.1 2.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.3 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.1 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 3.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 0.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.5 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 1.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.0 5.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 2.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 7.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.5 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.8 GO:0009975 cyclase activity(GO:0009975)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517) FAD transmembrane transporter activity(GO:0015230)
0.0 0.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.8 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 1.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 2.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 2.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade