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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxh1+foxq1a+foxq1b

Z-value: 0.69

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Transcription factors associated with foxh1+foxq1a+foxq1b

Gene Symbol Gene ID Gene Info
ENSDARG00000030896 forkhead box Q1a
ENSDARG00000055395 forkhead box Q1b
ENSDARG00000055630 forkhead box H1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxq1adr11_v1_chr2_-_722156_722170-0.409.1e-02Click!
foxh1dr11_v1_chr12_-_13729263_13729263-0.409.3e-02Click!
foxq1bdr11_v1_chr20_+_26683933_266839400.058.5e-01Click!

Activity profile of foxh1+foxq1a+foxq1b motif

Sorted Z-values of foxh1+foxq1a+foxq1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_15534815 2.21 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr18_+_20034023 1.55 ENSDART00000139441
mortality factor 4 like 1
chr22_+_15960005 1.55 ENSDART00000033617
scl/tal1 interrupting locus
chr22_+_15960514 1.52 ENSDART00000181617
scl/tal1 interrupting locus
chr22_+_15959844 1.44 ENSDART00000182201
scl/tal1 interrupting locus
chr8_+_39634114 1.41 ENSDART00000144293
musashi RNA-binding protein 1
chr4_+_21741228 1.41 ENSDART00000112035
ENSDART00000127664
myogenic factor 5
chr14_+_34495216 1.38 ENSDART00000147756
wingless-type MMTV integration site family, member 8a
chr25_+_18556588 1.35 ENSDART00000073726
caveolin 2
chr13_+_25286538 1.30 ENSDART00000180282
conserved helix-loop-helix ubiquitous kinase
chr1_+_26676758 1.26 ENSDART00000152299
si:dkey-25o16.4
chr10_+_22775253 1.23 ENSDART00000190141
transmembrane protein 88 a
chr1_+_25696798 1.23 ENSDART00000054228
lecithin retinol acyltransferase a
chr16_+_35536075 1.22 ENSDART00000183618
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr20_+_33294428 1.20 ENSDART00000024104
MYCN proto-oncogene, bHLH transcription factor
chr3_-_37148594 1.19 ENSDART00000140855
MLX, MAX dimerization protein
chr17_-_42213285 1.18 ENSDART00000140549
NK2 homeobox 2a
chr13_-_25198025 1.18 ENSDART00000159585
ENSDART00000144227
adenosine kinase a
chr1_+_19538299 1.18 ENSDART00000109416
structural maintenance of chromosomes 2
chr5_+_25762271 1.18 ENSDART00000181323
transmembrane protein 2
chr16_+_35535375 1.16 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr2_+_36701322 1.13 ENSDART00000002510
golgi integral membrane protein 4b
chr16_-_42461263 1.11 ENSDART00000109259
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr5_-_45958838 1.10 ENSDART00000135072
POC5 centriolar protein homolog (Chlamydomonas)
chr21_-_44772738 1.09 ENSDART00000026178
kinesin family member 4
chr16_-_30564319 1.05 ENSDART00000145087
lamin A
chr7_-_26076970 1.05 ENSDART00000101120
zgc:92664
chr14_+_28486213 1.04 ENSDART00000161852
stromal antigen 2b
chr7_-_51102479 1.04 ENSDART00000174023
collagen, type IV, alpha 6
chr13_+_23157053 1.03 ENSDART00000162359
sorbin and SH3 domain containing 1
chr17_-_42218652 1.03 ENSDART00000081396
ENSDART00000190007
NK2 homeobox 2a
chr7_-_54679595 1.02 ENSDART00000165320
cyclin D1
chr1_+_9290103 0.97 ENSDART00000055009
Unc4.1 homeobox (C. elegans)
chr20_-_25748407 0.96 ENSDART00000063152
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr9_+_34397843 0.96 ENSDART00000146314
mediator complex subunit 14
chr19_+_25971000 0.93 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr2_+_7132292 0.92 ENSDART00000153404
ENSDART00000012119
zgc:110366
chr16_+_11818126 0.89 ENSDART00000145727
chemokine (C-X-C motif) receptor 3, tandem duplicate 2
chr9_+_34950942 0.88 ENSDART00000077800
transcription factor Dp-1, a
chr11_+_37612214 0.87 ENSDART00000172899
ENSDART00000077496
heterochromatin protein 1, binding protein 3
chr17_-_42213822 0.87 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr11_+_25257022 0.86 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr1_-_45580787 0.85 ENSDART00000135089
activating transcription factor 7 interacting protein
chr5_-_67365750 0.85 ENSDART00000062359
uracil DNA glycosylase a
chr18_-_45761868 0.85 ENSDART00000025423
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr19_+_46240171 0.84 ENSDART00000162785
mitogen-activated protein kinase 15
chr16_-_30563129 0.84 ENSDART00000191716
lamin A
chr9_+_34397516 0.83 ENSDART00000011304
ENSDART00000192973
mediator complex subunit 14
chr1_+_14658801 0.83 ENSDART00000192194

chr14_-_24410673 0.82 ENSDART00000125923
chemokine (C-X-C motif) ligand 14
chr18_-_44316920 0.81 ENSDART00000098599
si:ch211-151h10.2
chr17_+_24590177 0.80 ENSDART00000092941
rearranged L-myc fusion
chr5_+_49744713 0.79 ENSDART00000133384
nuclear receptor subfamily 2, group F, member 1a
chr19_+_19777437 0.78 ENSDART00000170662
homeobox A3a
chr11_-_25257045 0.77 ENSDART00000130477
snail family zinc finger 1a
chr17_+_34244345 0.77 ENSDART00000006058
eukaryotic translation initiation factor 2, subunit 1 alpha a
chr5_+_32835219 0.75 ENSDART00000140832
ENSDART00000186055
si:ch211-208h16.4
chr3_+_22442445 0.75 ENSDART00000190921
WNK lysine deficient protein kinase 4b
chr10_-_6587066 0.75 ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr1_-_23370395 0.75 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr16_-_39267185 0.70 ENSDART00000058550
ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1 like
chr8_-_11324143 0.70 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr3_-_43356082 0.69 ENSDART00000171213
UNC homeobox
chr11_+_22134540 0.68 ENSDART00000190502
si:dkey-91m3.1
chr2_-_37956768 0.67 ENSDART00000034595
cerebellin 10
chr16_-_42186093 0.67 ENSDART00000076030
fibrillarin
chr2_+_15128418 0.67 ENSDART00000141921
Rho GTPase activating protein 29b
chr24_+_26329018 0.67 ENSDART00000145752
myoneurin
chr7_+_9290929 0.65 ENSDART00000128530
small nuclear ribonucleoprotein polypeptide A'
chr7_+_22801465 0.64 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr7_+_24494299 0.64 ENSDART00000087568
negative elongation factor complex member A
chr11_+_24046179 0.64 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr9_-_27398369 0.64 ENSDART00000186499
testis expressed 30
chr11_-_25257595 0.63 ENSDART00000123567
snail family zinc finger 1a
chr10_+_28428222 0.62 ENSDART00000135003
si:ch211-222e20.4
chr8_+_32719930 0.62 ENSDART00000145362
hemicentin 2
chr12_-_34887943 0.62 ENSDART00000027379
BRD4 interacting chromatin remodeling complex associated protein like
chr19_+_5143128 0.62 ENSDART00000138011
ENSDART00000108541
si:dkey-89b17.4
chr5_-_32074534 0.61 ENSDART00000112342
ENSDART00000135855
actin related protein 2/3 complex, subunit 5-like, b
chr1_+_32054159 0.60 ENSDART00000181442
steroid sulfatase (microsomal), isozyme S
chr22_-_29906764 0.60 ENSDART00000019786
structural maintenance of chromosomes 3
chr16_-_21692024 0.59 ENSDART00000123597
si:ch211-154o6.2
chr3_+_40289418 0.59 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr17_-_18888959 0.59 ENSDART00000080029
adenylate kinase 7b
chr8_-_20243389 0.59 ENSDART00000184904
alkaline ceramidase 1
chr23_+_28077953 0.58 ENSDART00000186122
ENSDART00000111570
solute carrier family 26, member 10
chr19_+_20177887 0.57 ENSDART00000008595
transformer 2 alpha homolog
chr4_+_23125689 0.57 ENSDART00000077854
MDM2 oncogene, E3 ubiquitin protein ligase
chr9_-_53666031 0.57 ENSDART00000126314
protocadherin 8
chr3_-_39695856 0.56 ENSDART00000148247
B9 protein domain 1
chr5_-_41531629 0.56 ENSDART00000051082
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr5_-_36328688 0.56 ENSDART00000011399
ephrin-B1
chr13_+_18507592 0.55 ENSDART00000142622
si:ch211-198a12.6
chr24_+_6107901 0.55 ENSDART00000156419
si:ch211-37e10.2
chr3_+_23710839 0.55 ENSDART00000151584
homeobox B4a
chr4_+_11723852 0.53 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr18_+_19648275 0.53 ENSDART00000100569
SMAD family member 6b
chr7_-_18547420 0.53 ENSDART00000173969
regulator of G protein signaling 12a
chr15_+_16185118 0.50 ENSDART00000147900
mitochondrial rRNA methyltransferase 3a
chr11_+_7580079 0.50 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr8_-_15150131 0.50 ENSDART00000138253
BCAR3, NSP family adaptor protein
chr19_+_19756425 0.49 ENSDART00000167606
homeobox A3a
chr12_+_27156943 0.49 ENSDART00000153030
ENSDART00000001737
src kinase associated phosphoprotein 1
chr18_-_5850683 0.49 ENSDART00000082087
NIP7, nucleolar pre-rRNA processing protein
chr7_+_30240791 0.48 ENSDART00000109243
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr25_+_2776865 0.47 ENSDART00000156567
neogenin 1b
chr6_-_19341184 0.47 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr3_-_39696066 0.47 ENSDART00000015393
B9 protein domain 1
chr7_+_38808027 0.46 ENSDART00000052323
harbinger transposase derived 1
chr15_-_7337537 0.46 ENSDART00000161613
high affinity cationic amino acid transporter 1
chr17_+_44441042 0.46 ENSDART00000142123
adaptor-related protein complex 5, mu 1 subunit
chr9_-_30494727 0.46 ENSDART00000148729
si:dkey-229b18.3
chr19_+_43004408 0.45 ENSDART00000038230
small nuclear ribonucleoprotein 40 (U5)
chr11_+_2172335 0.45 ENSDART00000170593
homeobox C12b
chr20_+_37300296 0.45 ENSDART00000180789
vesicle (multivesicular body) trafficking 1
chr3_+_40284598 0.44 ENSDART00000009411
BUD31 homolog (S. cerevisiae)
chr16_-_9675982 0.44 ENSDART00000113724
mal, T cell differentiation protein 2 (gene/pseudogene)
chr16_+_9580699 0.44 ENSDART00000165565
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_+_29726428 0.44 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr9_-_21067971 0.44 ENSDART00000004333
T-box 15
chr18_+_30421528 0.43 ENSDART00000140908
Gse1 coiled-coil protein
chr19_-_46018152 0.42 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr5_+_34623107 0.42 ENSDART00000184126
ectodermal-neural cortex 1
chr14_+_34966598 0.42 ENSDART00000004550
ring finger protein 145a
chr8_+_47726919 0.42 ENSDART00000160166
si:ch211-243p7.3
chr16_+_25116827 0.41 ENSDART00000163244
si:ch211-261d7.6
chr23_+_38159715 0.41 ENSDART00000137969
zgc:112994
chr2_-_10631767 0.41 ENSDART00000190033
metal response element binding transcription factor 2
chr5_-_28767573 0.40 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr2_+_8649293 0.39 ENSDART00000081442
ENSDART00000186024
far upstream element (FUSE) binding protein 1
chr8_+_11425048 0.39 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr18_+_40354998 0.39 ENSDART00000098791
ENSDART00000049171
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr17_-_12764360 0.37 ENSDART00000003418
breast cancer metastasis-suppressor 1-like a
chr8_+_48484455 0.37 ENSDART00000122737
si:ch211-263k4.2
chr15_-_36727462 0.37 ENSDART00000085971
nephrosis 1, congenital, Finnish type (nephrin)
chr20_-_16156419 0.37 ENSDART00000037420
Ral GEF with PH domain and SH3 binding motif 2
chr9_+_31282161 0.36 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr5_-_63509581 0.36 ENSDART00000097325
complement component 5
chr14_-_12391506 0.36 ENSDART00000080864
magnesium transporter 1
chr1_+_35790082 0.36 ENSDART00000085051
hedgehog interacting protein
chr15_-_37875601 0.36 ENSDART00000122439
si:dkey-238d18.4
chr19_+_32553874 0.36 ENSDART00000078197
hes-related family bHLH transcription factor with YRPW motif-like
chr7_+_30254652 0.35 ENSDART00000173711
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr24_-_26854032 0.35 ENSDART00000087991
fibronectin type III domain containing 3Bb
chr16_+_44906324 0.34 ENSDART00000074960
cd22 molecule
chr6_+_54680730 0.34 ENSDART00000074602
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr18_+_25225524 0.33 ENSDART00000055563
si:dkeyp-59c12.1
chr24_+_37338169 0.33 ENSDART00000141771
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr17_+_26803470 0.33 ENSDART00000023470
progesterone receptor membrane component 2
chr7_+_29080684 0.32 ENSDART00000173709
ENSDART00000173576
ACD, shelterin complex subunit and telomerase recruitment factor
chr3_+_34234029 0.32 ENSDART00000044859
zinc finger protein 207, a
chr21_+_17542473 0.32 ENSDART00000005750
ENSDART00000141326
stomatin
chr13_-_3155243 0.32 ENSDART00000139183
ENSDART00000050934
protein kinase domain containing, cytoplasmic a
chr14_-_15990361 0.32 ENSDART00000168075
tripartite motif containing 105
chr15_-_7337148 0.32 ENSDART00000182568
high affinity cationic amino acid transporter 1
chr23_+_25354856 0.31 ENSDART00000109023
ENSDART00000147440
formin-like 3
chr7_-_19999152 0.31 ENSDART00000173881
ENSDART00000100798
thyroid hormone receptor interactor 6
chr8_-_44223473 0.31 ENSDART00000098525
syntaxin 2b
chr21_-_13225402 0.31 ENSDART00000080347
WD repeat domain 34
chr23_+_2191773 0.31 ENSDART00000190876
ENSDART00000126768
coiled-coil and C2 domain containing 2A
chr1_+_46194333 0.31 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr15_+_23550890 0.30 ENSDART00000009796
ENSDART00000152720
si:dkey-31m14.7
chr4_+_2637947 0.30 ENSDART00000130623
dihydrouridine synthase 4-like (S. cerevisiae)
chr13_+_39182099 0.29 ENSDART00000131434
family with sequence similarity 135, member A
chr3_-_42086577 0.29 ENSDART00000083111
ENSDART00000187312
tweety family member 3a
chr11_+_27347076 0.29 ENSDART00000173383
fibulin 2
chr9_+_6802641 0.29 ENSDART00000187278

chr7_+_24153070 0.28 ENSDART00000076735
low density lipoprotein receptor-related protein 10
chr3_+_18062871 0.28 ENSDART00000112384
ankyrin repeat domain 40
chr15_+_21712328 0.28 ENSDART00000192553
zgc:162339
chr9_+_11293830 0.28 ENSDART00000144440
wingless-type MMTV integration site family, member 6b
chr3_-_50139860 0.28 ENSDART00000101563
bloodthirsty-related gene family, member 2
chr1_+_19083501 0.26 ENSDART00000002886
ENSDART00000131948
exosome component 9
chr16_+_24733741 0.26 ENSDART00000155217
si:dkey-79d12.4
chr12_-_34716037 0.26 ENSDART00000152876
BAH domain and coiled-coil containing 1b
chr19_+_33476557 0.26 ENSDART00000181800
triple QxxK/R motif containing
chr24_+_26328787 0.25 ENSDART00000003884
myoneurin
chr7_+_52761841 0.25 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr14_-_40389699 0.24 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr21_-_38153824 0.23 ENSDART00000151226
Kruppel-like factor 5 like
chr18_-_34156765 0.23 ENSDART00000059400
c18h3orf33 homolog (H. sapiens)
chr6_+_33881372 0.23 ENSDART00000165710
GC-rich promoter binding protein 1-like 1
chr4_+_25181572 0.22 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr18_+_6039141 0.22 ENSDART00000138972
si:ch73-386h18.1
chr23_+_36118738 0.22 ENSDART00000139319
homeobox C5a
chr11_+_24348425 0.21 ENSDART00000089747
NFS1 cysteine desulfurase
chr10_-_43117607 0.21 ENSDART00000148293
ENSDART00000089965
transmembrane protein 167A
chr9_+_8894788 0.21 ENSDART00000132068
NAD(P)HX dehydratase
chr1_+_24076243 0.21 ENSDART00000014608
mab-21-like 2
chr10_+_43117661 0.20 ENSDART00000024644
ENSDART00000186932
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_44282796 0.20 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr25_+_18711804 0.20 ENSDART00000011149
family with sequence similarity 185, member A
chr15_-_19334448 0.20 ENSDART00000062576
thymocyte nuclear protein 1
chr6_-_8466717 0.19 ENSDART00000151577
ENSDART00000151800
ENSDART00000151227
si:dkey-217d24.6
chr5_-_37997774 0.19 ENSDART00000139616
ENSDART00000167694
si:dkey-111e8.1
chr22_+_15624371 0.19 ENSDART00000124868
lipoprotein lipase
chr11_-_16215143 0.19 ENSDART00000027014
RAB7, member RAS oncogene family
chr7_+_52950449 0.19 ENSDART00000187559
CDKN2A interacting protein
chr17_+_33453689 0.17 ENSDART00000156894
Ras and Rab interactor 3
chr15_+_42285643 0.17 ENSDART00000152731
SR-related CTD-associated factor 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxh1+foxq1a+foxq1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 4.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.5 1.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 1.4 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.4 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 1.2 GO:1901295 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.4 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.9 GO:0090342 regulation of cell aging(GO:0090342)
0.3 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 0.9 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.3 1.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 1.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.2 GO:0044209 AMP salvage(GO:0044209)
0.2 1.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 2.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.2 1.3 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.7 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 1.0 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.9 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.2 0.3 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 1.0 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.2 0.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 1.2 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.6 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.3 GO:0071042 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 0.8 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.1 0.4 GO:0045056 transcytosis(GO:0045056)
0.1 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.6 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.7 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 0.9 GO:0070828 heterochromatin organization(GO:0070828)
0.1 1.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 1.8 GO:0019827 stem cell population maintenance(GO:0019827)
0.1 0.6 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.9 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.4 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.6 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.2 GO:0030238 male sex determination(GO:0030238)
0.1 1.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.6 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.2 GO:0051103 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.3 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 1.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 1.1 GO:0007632 visual behavior(GO:0007632)
0.0 0.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 1.2 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.9 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.3 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0031123 RNA 3'-end processing(GO:0031123)
0.0 0.1 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097189 apoptotic body(GO:0097189)
0.3 0.8 GO:0043614 multi-eIF complex(GO:0043614)
0.3 1.8 GO:0070847 core mediator complex(GO:0070847)
0.2 1.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.0 GO:0016589 NURF complex(GO:0016589)
0.2 1.0 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.6 GO:0032021 NELF complex(GO:0032021)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 1.6 GO:0008278 cohesin complex(GO:0008278)
0.1 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 4.6 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 1.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.4 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 1.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 0.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 1.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 0.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.6 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.9 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.1 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.2 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.5 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.8 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.7 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 2.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID ATM PATHWAY ATM pathway
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing