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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxc1a+foxc1b

Z-value: 0.82

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Transcription factors associated with foxc1a+foxc1b

Gene Symbol Gene ID Gene Info
ENSDARG00000055398 forkhead box C1b
ENSDARG00000091481 forkhead box C1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxc1adr11_v1_chr2_-_689047_689047-0.474.4e-02Click!
foxc1bdr11_v1_chr20_+_26702377_26702377-0.165.1e-01Click!

Activity profile of foxc1a+foxc1b motif

Sorted Z-values of foxc1a+foxc1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_46310204 3.54 ENSDART00000188713
ENSDART00000184930
crystallin, beta B1, like 1
chr22_+_20720808 2.87 ENSDART00000171321
si:dkey-211f22.5
chr2_-_22152797 2.24 ENSDART00000145188
cytochrome P450, family 7, subfamily A, polypeptide 1
chr21_-_43606502 2.23 ENSDART00000151030
si:ch73-362m14.4
chr1_-_22338521 2.21 ENSDART00000176849
si:ch73-380n15.2
chr12_-_22524388 2.13 ENSDART00000020942
sex hormone-binding globulin
chr7_+_23907692 2.08 ENSDART00000045479
synaptotagmin IV
chr15_-_12319065 2.07 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr10_+_2587234 1.96 ENSDART00000126937
wu:fb59d01
chr16_-_13818061 1.95 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr9_-_48736388 1.94 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr9_-_7421135 1.91 ENSDART00000144600
bridging integrator 1a
chr21_-_4032650 1.78 ENSDART00000151648
netrin g2b
chr25_+_20216159 1.73 ENSDART00000048642
troponin T2d, cardiac
chr8_+_53464216 1.71 ENSDART00000169514
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr15_+_47903864 1.61 ENSDART00000063835
orthodenticle homolog 5
chr4_-_4387012 1.58 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr1_-_54947592 1.56 ENSDART00000129710
cartilage acidic protein 1a
chr21_-_22114625 1.53 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr5_+_72087619 1.47 ENSDART00000062885
oxytocin
chr13_+_24552254 1.43 ENSDART00000147907
lectin, galactoside-binding-like b
chr1_+_7540978 1.43 ENSDART00000147770
myosin, light polypeptide 3, skeletal muscle
chr17_-_12336987 1.36 ENSDART00000172001
synaptosomal-associated protein, 25b
chr22_-_10486477 1.33 ENSDART00000184366
asporin (LRR class 1)
chr22_-_10487490 1.31 ENSDART00000064798
asporin (LRR class 1)
chr23_+_6272638 1.29 ENSDART00000190366
synaptotagmin IIa
chr22_+_5103349 1.27 ENSDART00000083474
ataxia, cerebellar, Cayman type a
chr19_-_19339285 1.25 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr11_+_30729745 1.23 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr1_-_45177373 1.22 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr8_+_19514294 1.22 ENSDART00000170622
si:ch73-281k2.5
chr23_-_24856025 1.21 ENSDART00000142171
synaptotagmin VIa
chr5_+_30680804 1.16 ENSDART00000078049
PDZ domain containing 3b
chr2_+_20430366 1.13 ENSDART00000155108
si:ch211-153l6.6
chr19_-_5103313 1.10 ENSDART00000037007
triosephosphate isomerase 1a
chr1_-_8101495 1.06 ENSDART00000161938
si:dkeyp-9d4.3
chr11_+_11200550 1.05 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr4_-_53370 1.03 ENSDART00000180254
ENSDART00000186529

chr16_-_42004544 1.00 ENSDART00000034544
caspase a
chr1_-_14332283 0.99 ENSDART00000090025
Wolfram syndrome 1a (wolframin)
chr24_-_21588914 0.98 ENSDART00000152054
G protein-coupled receptor 12
chr23_+_18944388 0.97 ENSDART00000104487
cytochrome c oxidase subunit IV isoform 2
chr18_-_41219790 0.95 ENSDART00000162387
ENSDART00000193753
zinc finger and BTB domain containing 38
chr3_-_40976463 0.93 ENSDART00000128450
ENSDART00000018676
cytochrome P450, family 3, subfamily c, polypeptide 1
chr22_+_31930650 0.93 ENSDART00000092090
dedicator of cytokinesis 3
chr9_-_7257877 0.92 ENSDART00000153514
si:ch211-121j5.4
chr12_-_26064480 0.92 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
LIM domain binding 3b
chr18_-_12858016 0.91 ENSDART00000130343
poly (ADP-ribose) polymerase family, member 12a
chr15_-_568645 0.91 ENSDART00000156744
cerebellin 18
chr25_-_31739309 0.91 ENSDART00000098896
acyl-CoA thioesterase 19
chr13_-_301309 0.85 ENSDART00000131747
chitin synthase 1
chr12_+_10116912 0.85 ENSDART00000189630
si:dkeyp-118b1.2
chr24_-_32408404 0.83 ENSDART00000144157
si:ch211-56a11.2
chr16_+_13818500 0.81 ENSDART00000135245
folliculin
chr3_-_18030938 0.81 ENSDART00000013540
si:ch73-141c7.1
chr2_-_50372467 0.78 ENSDART00000108900
contactin associated protein like 2b
chr7_-_38790341 0.77 ENSDART00000159884
si:dkey-23n7.10
chr8_-_46525092 0.76 ENSDART00000030482
sulfotransferase family 1, cytosolic sulfotransferase 2
chr8_-_15398760 0.75 ENSDART00000162011
ATP/GTP binding protein-like 4
chr5_+_25952340 0.73 ENSDART00000147188
transient receptor potential cation channel, subfamily M, member 3
chr12_-_24060358 0.72 ENSDART00000050831
ChaC, cation transport regulator homolog 2 (E. coli)
chr15_-_37921998 0.69 ENSDART00000193597
ENSDART00000181443
ENSDART00000168790
si:dkey-238d18.5
chr13_+_36680564 0.68 ENSDART00000136030
ENSDART00000006923
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr17_+_53250802 0.68 ENSDART00000143819
vasohibin 1
chr21_+_11105007 0.68 ENSDART00000128859
ENSDART00000193105
prolactin receptor a
chr20_-_3166168 0.67 ENSDART00000134137
si:ch73-212j7.3
chr16_-_12723324 0.67 ENSDART00000131915
SH3 domain binding kinase family, member 3
chr12_-_26064105 0.67 ENSDART00000168825
LIM domain binding 3b
chr1_-_7917062 0.67 ENSDART00000177068
monocyte to macrophage differentiation-associated 2b
chr7_-_28463106 0.67 ENSDART00000137799
tripartite motif containing 66
chr14_+_35013656 0.65 ENSDART00000164974
early B cell factor 3a
chr20_-_27311675 0.65 ENSDART00000026088
ENSDART00000148361
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr9_+_12890161 0.63 ENSDART00000146477
si:ch211-167j6.4
chr9_-_23994225 0.62 ENSDART00000140346
collagen, type VI, alpha 3
chr21_-_26250744 0.61 ENSDART00000044735
glutamate receptor, ionotropic, AMPA 1b
chr4_+_57093908 0.60 ENSDART00000170198
si:ch211-238e22.5
chr18_+_808911 0.60 ENSDART00000172518
cytochrome c oxidase subunit Vab
chr8_-_44015210 0.59 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
RIMS binding protein 2
RIMS binding protein 2
chr1_+_6817292 0.59 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr5_-_28029558 0.59 ENSDART00000078649
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr15_+_15456910 0.59 ENSDART00000155708
zgc:174895
chr8_-_18200003 0.59 ENSDART00000080014
ribosomal protein S8b
chr3_-_40976288 0.57 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr3_-_43770876 0.57 ENSDART00000160162
zgc:92162
chr24_-_25428176 0.57 ENSDART00000090010
phosphate regulating endopeptidase homolog, X-linked
chr9_-_3866707 0.56 ENSDART00000010378
myosin IIIB
chr13_-_47800342 0.56 ENSDART00000121817
fibulin 7
chr5_+_23597144 0.56 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
K(lysine) acetyltransferase 5b
chr17_-_465285 0.56 ENSDART00000168718
cholinergic receptor, muscarinic 5a
chr3_-_16227683 0.56 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr23_-_44819100 0.55 ENSDART00000076373
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1
chr20_-_46817223 0.55 ENSDART00000100336
estrogen-related receptor gamma b
chr7_-_22132265 0.52 ENSDART00000125284
ENSDART00000112978
neuroligin 2a
chr19_+_164013 0.51 ENSDART00000167379
capping protein regulator and myosin 1 linker 1
chr1_-_45341760 0.50 ENSDART00000149183
ENSDART00000148289
ENSDART00000110390
zgc:101679
chr7_-_31321027 0.49 ENSDART00000186878

chr21_+_6556635 0.49 ENSDART00000139598
procollagen, type V, alpha 1
chr2_+_6181383 0.47 ENSDART00000153307
si:ch73-344o19.1
chr5_-_67629263 0.46 ENSDART00000133753
zinc finger and BTB domain containing 20
chr11_-_29946927 0.46 ENSDART00000165182
zgc:113276
chr23_-_42752387 0.45 ENSDART00000149781
si:ch73-217n20.1
chr1_-_25679339 0.45 ENSDART00000161703
ENSDART00000054230
fibrinogen gamma chain
chr1_-_46326156 0.44 ENSDART00000040284
ATPase phospholipid transporting 11A
chr19_-_10730488 0.43 ENSDART00000126033
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 1
chr5_-_61942482 0.42 ENSDART00000097338
N-ethylmaleimide-sensitive factor attachment protein, alpha a
chr7_+_49695904 0.41 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr1_-_37383741 0.41 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr7_-_24373662 0.41 ENSDART00000173865
si:dkey-11k2.7
chr6_+_18359306 0.40 ENSDART00000157796
chromobox homolog 8b
chr5_-_23705828 0.40 ENSDART00000189419
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr10_+_15107886 0.40 ENSDART00000188047
ENSDART00000164095
secretory calcium-binding phosphoprotein 8
chr22_-_26175237 0.40 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr22_-_20386982 0.40 ENSDART00000089015
zinc finger and BTB domain containing 7a
chr20_+_38276690 0.39 ENSDART00000061437
chemokine (C-C motif) ligand 38, duplicate 6
chr8_-_29706882 0.39 ENSDART00000045909
perforin 1.5
chr7_+_9981757 0.36 ENSDART00000113429
ENSDART00000173233
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr4_+_12333168 0.34 ENSDART00000172455
ENSDART00000146166
Pim proto-oncogene, serine/threonine kinase, related 214
Pim proto-oncogene, serine/threonine kinase, related 171
chr3_-_16227490 0.34 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
calcium channel, voltage-dependent, beta 1 subunit
chr23_+_14269311 0.34 ENSDART00000170414

chr9_+_51180508 0.33 ENSDART00000138990
interferon induced with helicase C domain 1
chr5_-_18897482 0.33 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr8_-_36370552 0.33 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
chr22_-_23000815 0.32 ENSDART00000137111
protein tyrosine phosphatase, receptor type, C
chr6_+_42587637 0.31 ENSDART00000179964
CaM kinase-like vesicle-associated a
chr12_-_35095414 0.31 ENSDART00000153229
si:dkey-21e13.3
chr12_+_20641471 0.31 ENSDART00000133654
calcium binding and coiled-coil domain 2
chr5_+_31860043 0.31 ENSDART00000036235
ENSDART00000140541
iron-sulfur cluster assembly enzyme b
chr13_+_21601149 0.31 ENSDART00000179369
SH2 domain containing 4Ba
chr22_+_29135846 0.30 ENSDART00000143811
BAI1-associated protein 2-like 2b
chr22_-_7778895 0.29 ENSDART00000125489
si:ch73-44m9.3
chr13_+_28417297 0.28 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr16_-_9383629 0.28 ENSDART00000084264
ENSDART00000166958
adenylate cyclase 2a
chr17_-_33415740 0.28 ENSDART00000135218
coiled-coil domain containing 28A
chr6_+_52853384 0.27 ENSDART00000174155
ENSDART00000164391

chr22_+_24559947 0.27 ENSDART00000169847
WD repeat domain 47b
chr3_+_29641181 0.27 ENSDART00000151517
eukaryotic translation initiation factor 3, subunit D
chr25_+_19238175 0.26 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
diphosphoinositol pentakisphosphate kinase 1b
chr5_-_4219741 0.26 ENSDART00000100093
si:ch211-283g2.2
chr22_-_8860869 0.25 ENSDART00000166188

chr13_+_8696825 0.25 ENSDART00000109059
tetratricopeptide repeat domain 7A
chr5_+_37890521 0.25 ENSDART00000140207
transmembrane protease, serine 4b
chr4_-_25064510 0.24 ENSDART00000025153
GATA binding protein 3
chr9_-_7089303 0.23 ENSDART00000146609
cytochrome C oxidase assembly factor 5
chr13_+_21600946 0.23 ENSDART00000144045
SH2 domain containing 4Ba
chr24_-_36270855 0.23 ENSDART00000154858
si:ch211-40k21.5
chr18_-_16792561 0.22 ENSDART00000145546
adenosine monophosphate deaminase 3b
chr1_+_18550864 0.22 ENSDART00000142515
si:dkey-192k22.2
chr2_+_49644803 0.22 ENSDART00000160342
si:ch211-209f23.7
chr21_-_4918735 0.22 ENSDART00000150936
potassium channel, subfamily T, member 1
chr7_+_38762043 0.22 ENSDART00000036461
Rho GTPase activating protein 1
chr9_+_13985567 0.22 ENSDART00000102296
CD28 molecule
chr1_-_17663108 0.21 ENSDART00000131559
si:dkey-256e7.5
chr5_-_12687357 0.21 ENSDART00000193206
apoptosis-inducing factor, mitochondrion-associated, 3
chr20_+_28960340 0.21 ENSDART00000147917
G protein-coupled receptor 176
chr1_-_35113974 0.21 ENSDART00000192811
ENSDART00000167461

chr8_+_7737062 0.21 ENSDART00000166712
FYVE, RhoGEF and PH domain containing 1
chr5_-_54300725 0.20 ENSDART00000163048
solute carrier family 25, member 35
chr7_-_16214889 0.20 ENSDART00000076318
ENSDART00000173946
bloodthirsty-related gene family, member 6
chr15_-_36347858 0.20 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
chr1_-_37383539 0.20 ENSDART00000127579
secretory calcium-binding phosphoprotein 1
chr23_+_2185397 0.19 ENSDART00000109373
C1q and TNF related 7
chr9_+_18576047 0.19 ENSDART00000145174
laccase (multicopper oxidoreductase) domain containing 1
chr5_-_50640171 0.18 ENSDART00000183353
multiple C2 domains, transmembrane 1a
chr1_+_23274710 0.18 ENSDART00000036448
lipoic acid synthetase
chr16_+_28727383 0.18 ENSDART00000149753
DC-STAMP domain containing 2
chr1_+_35862550 0.17 ENSDART00000132118
si:ch211-194g2.4
chr5_-_57624425 0.16 ENSDART00000167892
zgc:193711
chr6_+_72040 0.16 ENSDART00000122957
crystallin, gamma M4
chr3_-_21062706 0.16 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
family with sequence similarity 57, member Ba
chr15_+_638457 0.15 ENSDART00000157162
zinc finger protein 1013
chr20_-_19365875 0.15 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
chr5_-_35201482 0.15 ENSDART00000166272
FCH domain only 2
chr10_+_23520952 0.15 ENSDART00000125317
zmp:0000000937
chr12_-_31794908 0.14 ENSDART00000105583
ENSDART00000153449
N-acetyltransferase 9 (GCN5-related, putative)
chr19_-_17526735 0.14 ENSDART00000189391
thyroid hormone receptor beta
chr19_-_18667130 0.14 ENSDART00000164833
ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like 3
chr8_+_54263946 0.13 ENSDART00000193119
transmembrane and coiled-coil domain family 1
chr4_+_12358822 0.13 ENSDART00000172557
ENSDART00000150627
Pim proto-oncogene, serine/threonine kinase, related 168
chr15_-_6966221 0.12 ENSDART00000165487
ENSDART00000027657
mitochondrial ribosomal protein S22
chr9_+_12896340 0.12 ENSDART00000136417
si:ch211-167j6.5
chr3_+_25825043 0.12 ENSDART00000153749
phosphoinositide-3-kinase, regulatory subunit 6b
chr6_+_9398074 0.12 ENSDART00000151772
kalirin RhoGEF kinase b
chr4_-_14899113 0.12 ENSDART00000137829
si:dkey-14k9.3
chr20_+_51478939 0.12 ENSDART00000149758
toll-like receptor 5a
chr6_+_18441331 0.10 ENSDART00000171005
si:dkey-31g6.4
chr17_+_45472608 0.10 ENSDART00000103493
ENSDART00000183474
zgc:110783
chr21_+_34976600 0.09 ENSDART00000191672
ENSDART00000139635
RNA binding motif protein 11
chr24_-_10917243 0.09 ENSDART00000144372
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr22_+_2632961 0.09 ENSDART00000106278
zinc finger protein 1173
chr6_-_51771634 0.09 ENSDART00000073847
bladder cancer associated protein
chr2_-_36914281 0.09 ENSDART00000008322
si:dkey-193b15.5
chr25_+_16601839 0.09 ENSDART00000008986
ATPase H+ transporting V1 subunit E1a
chr5_-_61431809 0.08 ENSDART00000082952
RCC1 like
chr9_-_370225 0.08 ENSDART00000163637
si:dkey-11f4.7
chr4_+_12342173 0.08 ENSDART00000161518
Pim proto-oncogene, serine/threonine kinase, related 214
chr6_-_24384654 0.08 ENSDART00000164723
bromodomain, testis-specific
chr2_-_11096489 0.08 ENSDART00000156753
leucine rich repeat containing 53
chr16_-_40155424 0.07 ENSDART00000191763

chr6_-_8480815 0.07 ENSDART00000162300
RAS protein activator like 3
chr25_-_3087556 0.07 ENSDART00000193249
bestrophin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxc1a+foxc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.3 1.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.2 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.2 0.5 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.9 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 0.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 3.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 0.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 1.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 2.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.2 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.7 GO:0050951 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 4.6 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 1.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.8 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.6 GO:0032475 otolith formation(GO:0032475)
0.1 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 1.8 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.3 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.5 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 1.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 2.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.6 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.8 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.1 GO:0019835 cytolysis(GO:0019835)
0.0 1.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 1.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0043703 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.0 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 3.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.9 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.8 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 1.7 GO:0070509 calcium ion import(GO:0070509)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.1 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.1 GO:0014829 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) vascular smooth muscle contraction(GO:0014829) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.0 GO:0061702 inflammasome complex(GO:0061702)
0.2 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.2 2.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 1.8 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 5.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.5 GO:0099503 secretory vesicle(GO:0099503)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.4 1.2 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.3 1.9 GO:0048156 tau protein binding(GO:0048156)
0.3 1.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 2.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.6 GO:0046978 TAP1 binding(GO:0046978)
0.2 0.6 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.7 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 1.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 4.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 2.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 2.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.3 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.0 3.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.3 GO:0042562 hormone binding(GO:0042562)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling