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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxa3

Z-value: 1.40

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Transcription factors associated with foxa3

Gene Symbol Gene ID Gene Info
ENSDARG00000012788 forkhead box A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxa3dr11_v1_chr18_-_46354269_463542690.532.1e-02Click!

Activity profile of foxa3 motif

Sorted Z-values of foxa3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_36513605 3.08 ENSDART00000013590
wingless-type MMTV integration site family, member 11
chr5_-_20194876 2.85 ENSDART00000122587
D-amino-acid oxidase, tandem duplicate 1
chr7_-_32020100 2.30 ENSDART00000185433
kinesin family member 18A
chr12_+_27537357 2.28 ENSDART00000136212
ets variant 4
chr3_-_50865079 2.20 ENSDART00000164295
peripheral myelin protein 22a
chr5_-_54712159 2.15 ENSDART00000149207
cyclin B1
chr18_+_20566817 2.05 ENSDART00000100716
BH3 interacting domain death agonist
chr17_+_24718272 2.03 ENSDART00000007271
mitochondrial fission regulator 1-like
chr16_-_21785261 2.01 ENSDART00000078858
si:ch73-86n18.1
chr4_+_14926948 1.95 ENSDART00000019647
proteasome 26S subunit, ATPase 2
chr24_+_19542323 1.93 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr8_+_39795918 1.91 ENSDART00000143413
si:ch211-170d8.2
chr16_+_38940758 1.90 ENSDART00000102482
ENSDART00000136215
enhancer of yellow 2 homolog (Drosophila)
chr2_-_57264262 1.85 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
methyl-CpG binding domain protein 3a
chr4_+_14981854 1.84 ENSDART00000067046
cation/H+ exchanger protein 1
chr4_-_6373735 1.82 ENSDART00000140100
si:ch73-156e19.1
chr19_-_43757568 1.76 ENSDART00000058491
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr16_+_23978978 1.75 ENSDART00000058964
ENSDART00000135084
apolipoprotein A-II
chr3_+_23743139 1.73 ENSDART00000187409
homeobox B3a
chr14_-_16082806 1.72 ENSDART00000165656
MAX dimerization protein 3
chr20_+_29209615 1.68 ENSDART00000062350
katanin p80 subunit B-like 1
chr1_+_9153141 1.67 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr19_+_22347627 1.67 ENSDART00000109157
F-box and leucine-rich repeat protein 6
chr13_+_5978809 1.66 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr17_-_42218652 1.63 ENSDART00000081396
ENSDART00000190007
NK2 homeobox 2a
chr4_-_16451375 1.63 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr1_+_21309386 1.62 ENSDART00000054442
ENSDART00000145661
mediator complex subunit 28
chr11_-_36350421 1.60 ENSDART00000141477
proteasome subunit alpha 5
chr7_-_26844064 1.59 ENSDART00000162241
si:ch211-107p11.3
chr11_-_11336986 1.58 ENSDART00000016677
zgc:77929
chr9_-_24030795 1.47 ENSDART00000144163
ribulose-5-phosphate-3-epimerase
chr20_-_9980318 1.47 ENSDART00000080664
zgc:86709
chr7_+_52712807 1.45 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr24_+_23716918 1.44 ENSDART00000080332
COP9 signalosome subunit 5
chr1_+_11107688 1.44 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr19_+_1873059 1.42 ENSDART00000145246
small nuclear ribonucleoprotein D1 polypeptide
chr7_-_8417315 1.42 ENSDART00000173046
jacalin 1
chr2_-_30200206 1.41 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr1_+_29162478 1.39 ENSDART00000141441
ankyrin repeat domain 10a
chr8_+_25902170 1.37 ENSDART00000193130
ras homolog gene family, member Ab
chr8_-_19313510 1.37 ENSDART00000164780
ENSDART00000137133
ral guanine nucleotide dissociation stimulator-like 1
chr11_-_36350876 1.36 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr9_-_6661657 1.35 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
POU class 3 homeobox 3a
chr16_-_35952789 1.33 ENSDART00000180118
eva-1 homolog Ba (C. elegans)
chr9_+_53725294 1.33 ENSDART00000165991
chondromodulin
chr9_+_53725128 1.33 ENSDART00000169062
chondromodulin
chr9_+_44431174 1.33 ENSDART00000149726
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr21_+_43172506 1.33 ENSDART00000121725
zinc finger, CCHC domain containing 10
chr6_+_41446541 1.31 ENSDART00000029553
ENSDART00000128756
ENSDART00000144864
REM2 and RAB-like small GTPase 1
chr10_-_14545658 1.30 ENSDART00000057865
immediate early response 3 interacting protein 1
chr18_-_44847855 1.30 ENSDART00000086823
signal recognition particle receptor (docking protein)
chr18_-_19005919 1.29 ENSDART00000129776
integrator complex subunit 14
chr21_+_30549512 1.28 ENSDART00000132831
RAB38c, member of RAS oncogene family
chr1_-_55166511 1.26 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr2_-_32262287 1.25 ENSDART00000056621
ENSDART00000039717
family with sequence similarity 49, member Ba
chr23_-_44848961 1.25 ENSDART00000136839
wu:fb72h05
chr19_-_10324182 1.23 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
U2 small nuclear RNA auxiliary factor 2b
chr20_+_29209767 1.22 ENSDART00000141252
katanin p80 subunit B-like 1
chr2_+_25840463 1.22 ENSDART00000125178
eukaryotic translation initiation factor 5A2
chr23_+_36653376 1.22 ENSDART00000053189
G protein-coupled receptor 182
chr16_+_20904754 1.20 ENSDART00000006043
homeobox A11b
chr20_+_38671894 1.19 ENSDART00000146544
MpV17 mitochondrial inner membrane protein
chr16_+_23961276 1.18 ENSDART00000192754
apolipoprotein Eb
chr13_-_32726178 1.18 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr12_+_17154655 1.18 ENSDART00000028003
ankyrin repeat domain 22
chr14_-_17588345 1.16 ENSDART00000143486
selenoprotein T, 2
chr4_-_74466703 1.15 ENSDART00000174032
ENSDART00000189417

chr21_-_32081552 1.14 ENSDART00000135659
methionine adenosyltransferase II, beta
chr8_-_16697912 1.13 ENSDART00000076542
retinal pigment epithelium-specific protein 65b
chr21_-_40938382 1.13 ENSDART00000008593
Yip1 domain family, member 5
chr25_-_14433503 1.13 ENSDART00000103957
exocyst complex component 3-like 1
chr24_-_37272116 1.13 ENSDART00000022999
ubiquitin-conjugating enzyme E2Ib
chr18_-_40884087 1.13 ENSDART00000059194
small nuclear ribonucleoprotein D2 polypeptide
chr12_-_8504278 1.12 ENSDART00000135865
early growth response 2b
chr1_+_26667872 1.11 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemogen
chr2_-_44777592 1.09 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr21_-_26490186 1.09 ENSDART00000009889
zgc:110540
chr16_-_30564319 1.08 ENSDART00000145087
lamin A
chr17_+_51262556 1.08 ENSDART00000186748
ENSDART00000181606
ENSDART00000063738
ENSDART00000189066
EARP complex and GARP complex interacting protein 1
chr21_-_21020708 1.07 ENSDART00000064032
eukaryotic translation initiation factor 4E binding protein 1
chr10_+_10728870 1.07 ENSDART00000109282
SWI5 homologous recombination repair protein
chr24_-_21172122 1.05 ENSDART00000154259
ATPase H+ transporting V1 subunit Ab
chr14_-_25040359 1.05 ENSDART00000162556
si:rp71-1d10.5
chr6_-_13206255 1.05 ENSDART00000065373
eukaryotic translation elongation factor 1 beta 2
chr17_-_42213285 1.04 ENSDART00000140549
NK2 homeobox 2a
chr16_-_44673851 1.04 ENSDART00000015139
ddb1 and cul4 associated factor 13
chr5_+_49744713 1.03 ENSDART00000133384
nuclear receptor subfamily 2, group F, member 1a
chr5_+_26913120 1.03 ENSDART00000126609
T-box 3b
chr6_-_54444929 1.02 ENSDART00000154121
Sys1 golgi trafficking protein
chr21_-_17037907 1.02 ENSDART00000101263
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr17_-_28707898 1.01 ENSDART00000135752
ENSDART00000061853
adaptor-related protein complex 4, sigma 1 subunit
chr3_+_61523035 1.01 ENSDART00000106530
zinc finger protein 1004
chr11_-_30634286 1.00 ENSDART00000191019
zgc:153665
chr21_-_39081107 1.00 ENSDART00000075935
vitronectin b
chr23_-_16843649 0.99 ENSDART00000129971
si:dkey-63j12.4
chr7_+_26844261 0.99 ENSDART00000079165
exostosin glycosyltransferase 2
chr3_-_37571601 0.99 ENSDART00000016407
ADP-ribosylation factor 2a
chr16_+_23913943 0.99 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr21_+_26522571 0.99 ENSDART00000134617
adenylosuccinate synthase, like
chr15_+_21252532 0.98 ENSDART00000162619
ENSDART00000019636
ENSDART00000144901
ENSDART00000138676
ENSDART00000133821
ENSDART00000146967
ENSDART00000143990
ENSDART00000142070
ENSDART00000132373
upstream transcription factor 1
chr7_+_38808027 0.98 ENSDART00000052323
harbinger transposase derived 1
chr5_-_63302944 0.97 ENSDART00000047110
gelsolin b
chr22_+_20169352 0.97 ENSDART00000169055
ENSDART00000061617
high mobility group 20B
chr16_-_11986321 0.96 ENSDART00000148666
ENSDART00000029121
ubiquitin specific peptidase 5 (isopeptidase T)
chr4_+_42450386 0.96 ENSDART00000168211
si:dkey-11d20.1
chr14_-_31488100 0.95 ENSDART00000186246
calcium binding protein 39, like 1
chr20_+_30378803 0.95 ENSDART00000148242
ENSDART00000169140
ENSDART00000062441
ribonuclease H1
chr14_-_25985698 0.94 ENSDART00000172909
ENSDART00000123053
antioxidant 1 copper chaperone
chr17_+_43595692 0.94 ENSDART00000156271
cilia and flagella associated protein 99
chr19_+_20178978 0.93 ENSDART00000145115
ENSDART00000151175
transformer 2 alpha homolog
chr7_+_24023653 0.93 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr1_-_54622227 0.93 ENSDART00000049010
tektin 4
chr18_-_14337450 0.92 ENSDART00000061435
heat shock factor binding protein 1b
chr5_-_14509137 0.92 ENSDART00000180742
si:ch211-244o22.2
chr16_-_17713859 0.92 ENSDART00000149275
zgc:174935
chr5_+_63302660 0.91 ENSDART00000142131
si:ch73-376l24.2
chr20_+_29209926 0.90 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr4_-_1824836 0.90 ENSDART00000111858
mitochondrial ribosomal protein L42
chr4_-_12795030 0.90 ENSDART00000150427
beta-2-microglobulin
chr16_+_33163858 0.90 ENSDART00000101943
Ras-related GTP binding Ca
chr24_-_25461267 0.89 ENSDART00000105820
membrane-bound transcription factor peptidase, site 2
chr22_-_21176269 0.88 ENSDART00000112839
required for excision 1-B domain containing
chr11_-_31172276 0.86 ENSDART00000171520
si:dkey-238i5.3
chr5_+_29726428 0.86 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr3_-_57762247 0.86 ENSDART00000156522
calcium activated nucleotidase 1a
chr1_-_44940830 0.85 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr7_-_33023404 0.85 ENSDART00000052383
CD81 molecule a
chr19_-_46018152 0.84 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr3_-_27065477 0.84 ENSDART00000185660
activating transcription factor 7 interacting protein 2
chr15_+_23528010 0.83 ENSDART00000152786
si:dkey-182i3.8
chr20_-_10120442 0.83 ENSDART00000144970
Meis homeobox 2b
chr15_+_23528310 0.83 ENSDART00000152523
si:dkey-182i3.8
chr8_-_3312384 0.82 ENSDART00000035965
fucosyltransferase 9b
chr6_-_53048291 0.81 ENSDART00000103267
family with sequence similarity 212, member Ab
chr14_-_33894915 0.81 ENSDART00000143290
urotensin-related peptide 1
chr17_+_8799661 0.80 ENSDART00000105326
tonsoku-like, DNA repair protein
chr18_+_6857071 0.79 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr8_-_20245892 0.79 ENSDART00000136911
alkaline ceramidase 1
chr14_-_36799280 0.79 ENSDART00000168615
ring finger protein 130
chr25_-_21280584 0.79 ENSDART00000143644
transmembrane protein 60
chr15_+_24644016 0.79 ENSDART00000043292
smoothelin, like
chr11_+_7528599 0.79 ENSDART00000171813
adhesion G protein-coupled receptor L2a
chr4_+_10721795 0.79 ENSDART00000136000
ENSDART00000067253
stabilin 2
chr25_-_35101396 0.78 ENSDART00000138865
zgc:162611
chr23_+_27703749 0.77 ENSDART00000027224
limb development membrane protein 1-like
chr6_-_40851499 0.77 ENSDART00000182591
RFT1 homolog
chr9_+_52411530 0.76 ENSDART00000163684
NME/NM23 family member 8
chr9_+_34950942 0.76 ENSDART00000077800
transcription factor Dp-1, a
chr19_+_30867845 0.75 ENSDART00000047461
major facilitator superfamily domain containing 2ab
chr19_-_19720744 0.74 ENSDART00000170636
even-skipped homeobox 1
chr15_-_7337537 0.74 ENSDART00000161613
high affinity cationic amino acid transporter 1
chr6_+_13206516 0.74 ENSDART00000036927
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr25_-_35101673 0.74 ENSDART00000140864
zgc:162611
chr16_-_41714988 0.74 ENSDART00000138798
centrosomal protein 85
chr5_+_11944054 0.74 ENSDART00000159448
zgc:110063
chr23_+_9206350 0.73 ENSDART00000136236
si:dkey-66g10.2
chr9_-_27719998 0.73 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
general transcription factor IIE, polypeptide 1, alpha
chr23_-_36449111 0.73 ENSDART00000110478
zgc:174906
chr6_-_41135215 0.73 ENSDART00000001861
solute carrier family 6 member 22, tandem duplicate 1
chr8_-_16712111 0.73 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
retinal pigment epithelium-specific protein 65c
chr6_+_52895008 0.72 ENSDART00000136143
odorant receptor, family H, subfamily 137, member 7
chr6_+_52903302 0.71 ENSDART00000143962
odorant receptor, family H, subfamily 137, member 6
chr16_-_8280885 0.71 ENSDART00000129068
ectonucleoside triphosphate diphosphohydrolase 3
chr7_-_37555208 0.71 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr11_+_2416064 0.70 ENSDART00000067117
ubiquitin-conjugating enzyme E2 variant 1
chr14_-_29799993 0.69 ENSDART00000133775
ENSDART00000005568
PDZ and LIM domain 3b
chr2_+_25839940 0.69 ENSDART00000139927
eukaryotic translation initiation factor 5A2
chr1_+_38362412 0.69 ENSDART00000075086
centrosomal protein 44
chr2_-_32670883 0.69 ENSDART00000192586
ENSDART00000191410
poly-U binding splicing factor a
chr25_-_25142387 0.69 ENSDART00000031814
tumor susceptibility 101a
chr8_+_49570884 0.69 ENSDART00000182117
ENSDART00000108613
RAS and EF-hand domain containing
chr3_+_32571929 0.69 ENSDART00000151025
si:ch73-248e21.1
chr2_-_37277626 0.68 ENSDART00000135340
NAD kinase b
chr6_-_10728057 0.67 ENSDART00000002247
Sp3b transcription factor
chr21_+_40195452 0.66 ENSDART00000108650
odorant receptor, family F, subfamily 115, member 15
chr18_-_15532016 0.66 ENSDART00000165279
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr7_+_19850889 0.65 ENSDART00000100782
MUS81 structure-specific endonuclease subunit
chr13_+_42544009 0.65 ENSDART00000145409
si:dkey-221j11.3
chr20_+_54274431 0.65 ENSDART00000099338
ARP10 actin related protein 10 homolog
chr20_+_15015557 0.65 ENSDART00000039345
myocilin
chr1_+_33647682 0.65 ENSDART00000114384
zinc finger protein 654
chr4_-_20135919 0.64 ENSDART00000172230
centrosomal protein 83
chr11_-_7380674 0.64 ENSDART00000014979
ENSDART00000103418
vitellogenin 3, phosvitinless
chr19_-_17996336 0.64 ENSDART00000186143
ENSDART00000080751
integrator complex subunit 8
chr7_-_13906409 0.64 ENSDART00000062257
solute carrier family 39 (zinc transporter), member 1
chr15_-_26552393 0.64 ENSDART00000150152
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr23_-_29357764 0.63 ENSDART00000156512
si:ch211-129o18.4
chr21_+_20386865 0.63 ENSDART00000144366
si:dkey-30k6.5
chr5_+_34622320 0.63 ENSDART00000141338
ectodermal-neural cortex 1
chr2_+_1988036 0.63 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr9_-_29497916 0.62 ENSDART00000060246
DnaJ (Hsp40) homolog, subfamily C, member 3a
chr10_+_31951338 0.62 ENSDART00000019416
LHFPL tetraspan subfamily member 6
chr2_-_27330181 0.61 ENSDART00000137053
thioredoxin related transmembrane protein 3a
chr21_-_18991165 0.61 ENSDART00000012574
si:ch211-222n4.6
chr3_+_32492467 0.60 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr16_-_25233515 0.60 ENSDART00000058943
zgc:110182
chr15_-_25571865 0.60 ENSDART00000077836
matrix metallopeptidase 20b (enamelysin)
chr15_+_7176182 0.60 ENSDART00000101578
hairy-related 8.2
chr7_-_27033080 0.59 ENSDART00000173516
nucleobindin 2a
chr8_-_14184423 0.59 ENSDART00000063817
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11

Network of associatons between targets according to the STRING database.

First level regulatory network of foxa3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.7 2.9 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.7 3.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 2.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.5 1.5 GO:0019323 pentose catabolic process(GO:0019323)
0.5 1.9 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.4 1.2 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.4 1.2 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.4 1.4 GO:0000338 protein deneddylation(GO:0000338)
0.4 2.5 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3 1.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 1.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.3 1.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 1.9 GO:0016578 histone deubiquitination(GO:0016578)
0.2 0.7 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 1.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.2 2.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 1.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 0.6 GO:0002369 T cell cytokine production(GO:0002369)
0.2 0.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 1.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.6 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.2 0.4 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.1 GO:0090342 regulation of cell aging(GO:0090342)
0.2 0.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.2 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.5 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 0.5 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.2 1.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 2.3 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.7 GO:0045056 transcytosis(GO:0045056)
0.1 1.9 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 1.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.6 GO:0097186 amelogenesis(GO:0097186)
0.1 1.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.9 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 1.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.7 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 1.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 3.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 2.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.9 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.9 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 3.1 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.7 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 1.1 GO:0048938 myelination of lateral line nerve axons(GO:0048897) posterior lateral line nerve glial cell differentiation(GO:0048931) myelination of posterior lateral line nerve axons(GO:0048932) lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048938) posterior lateral line nerve glial cell development(GO:0048941) posterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048942)
0.1 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 1.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.5 GO:0032438 melanosome organization(GO:0032438)
0.1 0.5 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074) pharyngeal muscle development(GO:0043282)
0.1 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.4 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 1.2 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.6 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 2.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 2.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.3 GO:0090467 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 1.5 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.5 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.8 GO:0031297 replication fork processing(GO:0031297)
0.0 1.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.6 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.7 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.5 GO:0003205 cardiac chamber development(GO:0003205)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0060052 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299) neurofilament cytoskeleton organization(GO:0060052)
0.0 1.0 GO:0014029 neural crest formation(GO:0014029)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 1.9 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.7 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.6 GO:0032355 response to estradiol(GO:0032355)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.8 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0 0.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 1.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.5 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.9 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.5 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 1.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.6 2.3 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.4 1.9 GO:0070390 transcription export complex 2(GO:0070390)
0.3 1.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 3.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 0.9 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.9 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.5 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.4 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 1.2 GO:0089701 U2AF(GO:0089701)
0.1 1.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.7 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.7 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 1.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 1.9 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.2 GO:0070187 telosome(GO:0070187)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 2.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 1.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 2.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.3 GO:0030132 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130) clathrin coat of coated pit(GO:0030132)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 3.3 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.5 1.9 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.5 1.8 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.4 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 1.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 1.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 1.0 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 0.6 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 0.9 GO:0016531 copper chaperone activity(GO:0016531)
0.2 2.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.6 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.6 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 3.6 GO:0005109 frizzled binding(GO:0005109)
0.1 1.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0048256 flap endonuclease activity(GO:0048256)
0.1 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 3.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 1.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0008126 acetylesterase activity(GO:0008126)
0.0 1.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 1.2 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 2.8 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 5.1 GO:0003924 GTPase activity(GO:0003924)
0.0 2.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 3.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis