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PRJEB1986: zebrafish developmental stages transcriptome

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Results for figla

Z-value: 1.35

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Transcription factors associated with figla

Gene Symbol Gene ID Gene Info
ENSDARG00000087166 folliculogenesis specific bHLH transcription factor
ENSDARG00000115572 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
figladr11_v1_chr5_-_13848296_138482960.331.7e-01Click!

Activity profile of figla motif

Sorted Z-values of figla motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_25472758 1.73 ENSDART00000011178
opsin 1 (cone pigments), short-wave-sensitive 2
chr19_+_31904836 1.67 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr23_+_42414652 1.45 ENSDART00000171119
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr2_-_37893910 1.29 ENSDART00000143027
hexose-binding lectin 2
chr8_-_25247284 1.25 ENSDART00000132697
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr6_+_42338309 1.24 ENSDART00000015277
glutathione peroxidase 1b
chr13_+_50375800 1.19 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr6_-_52348562 1.17 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr16_-_17207754 1.16 ENSDART00000063804
wu:fj39g12
chr6_-_37459759 1.10 ENSDART00000190666
si:dkey-66a8.7
chr18_-_14337065 1.09 ENSDART00000135703
heat shock factor binding protein 1b
chr19_-_30404096 1.02 ENSDART00000103475
anterior gradient 2
chr9_+_159720 1.02 ENSDART00000166215
claudin 10-like 2
chr19_+_9174166 1.01 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
chr7_-_18881358 1.01 ENSDART00000021502
MLLT3, super elongation complex subunit
chr17_+_23462972 1.00 ENSDART00000112959
ENSDART00000192168
ankyrin repeat domain 1a (cardiac muscle)
chr22_-_10470663 1.00 ENSDART00000143352
osteomodulin
chr8_-_50287949 0.99 ENSDART00000023639
NK2 transcription factor related 7
chr6_-_607063 0.99 ENSDART00000189900
lectin, galactoside-binding, soluble, 2b
chr6_-_37749711 0.99 ENSDART00000078324
non imprinted in Prader-Willi/Angelman syndrome 1
chr8_-_8698607 0.95 ENSDART00000046712
zgc:86609
chr4_+_5537101 0.95 ENSDART00000008692
si:dkey-14d8.7
chr18_-_37241080 0.94 ENSDART00000126421
ENSDART00000078064
SIX homeobox 9
chr25_+_5012791 0.94 ENSDART00000156970
si:ch73-265h17.5
chr12_-_28818720 0.91 ENSDART00000134453
ENSDART00000141727
proline rich 15-like b
chr4_-_8043839 0.90 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr8_-_39760427 0.89 ENSDART00000184336
ENSDART00000186500
si:ch211-170d8.8
chr10_-_1961930 0.89 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr3_+_49021079 0.89 ENSDART00000162012
zgc:163083
chr3_+_17910569 0.87 ENSDART00000080946
tetratricopeptide repeat domain 25
chr7_-_35066457 0.84 ENSDART00000058067
zgc:112160
chr9_+_29985010 0.81 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr18_+_21061216 0.80 ENSDART00000141739
family with sequence similarity 169, member B
chr4_-_20483954 0.78 ENSDART00000187240
N-acyl phosphatidylethanolamine phospholipase D
chr10_-_1961576 0.78 ENSDART00000042441
teratocarcinoma-derived growth factor 1
chr19_-_30403922 0.77 ENSDART00000181841
anterior gradient 2
chr16_+_17715243 0.76 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
chr18_+_25003207 0.75 ENSDART00000099476
ENSDART00000132285
family with sequence similarity 174, member B
chr12_+_33484458 0.75 ENSDART00000000069
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr20_+_18580176 0.74 ENSDART00000185310
si:dkeyp-72h1.1
chr5_+_28271412 0.74 ENSDART00000031727
vesicle-associated membrane protein 8 (endobrevin)
chr20_+_38725662 0.74 ENSDART00000181873
urotensin 1
chr21_-_17016788 0.72 ENSDART00000186703

chr10_+_33171501 0.72 ENSDART00000159666
myosin, light chain 10, regulatory
chr15_+_36115955 0.72 ENSDART00000032702
somatostatin 1, tandem duplicate 2
chr15_+_19783352 0.71 ENSDART00000178784
ENSDART00000092560
zona pellucida-like domain containing 1b
chr23_+_42336084 0.71 ENSDART00000158959
ENSDART00000161812
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr21_+_11776328 0.71 ENSDART00000134469
ENSDART00000081646
glutaredoxin (thioltransferase)
chr6_-_37460178 0.71 ENSDART00000153500
si:dkey-66a8.7
chr22_+_26400519 0.70 ENSDART00000159839
ENSDART00000144585
calpain 8
chr14_-_16810401 0.70 ENSDART00000158396
ENSDART00000170758
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_+_36234335 0.70 ENSDART00000193484
ENSDART00000181664
cornichon family AMPA receptor auxiliary protein 3
chr2_+_37480669 0.69 ENSDART00000029801
signal peptide peptidase-like 2
chr23_+_25893020 0.69 ENSDART00000144769
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr3_+_34121156 0.69 ENSDART00000174929
aldehyde dehydrogenase 3 family, member B1
chr14_+_32964 0.68 ENSDART00000166173
Ly1 antibody reactive homolog (mouse)
chr21_-_21178410 0.68 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
FtsJ RNA methyltransferase homolog 1
chr18_-_14337450 0.67 ENSDART00000061435
heat shock factor binding protein 1b
chr16_-_45854882 0.67 ENSDART00000027013
ENSDART00000128068
neurotrophic tyrosine kinase, receptor, type 1
chr22_+_19111444 0.67 ENSDART00000109655
fibroblast growth factor 22
chr11_+_31285127 0.67 ENSDART00000160154
si:dkey-238i5.2
chr8_-_30242706 0.66 ENSDART00000139864
ENSDART00000143809
zgc:162939
chr22_-_26524596 0.66 ENSDART00000087623
zgc:194330
chr6_-_54290227 0.66 ENSDART00000050483
SAM pointed domain containing ETS transcription factor
chr22_-_17677947 0.66 ENSDART00000139911
tight junction protein 3
chr13_-_12581388 0.66 ENSDART00000079655
glutamyl aminopeptidase
chr2_-_52795722 0.65 ENSDART00000193307

chr4_-_4834347 0.65 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr4_-_277081 0.64 ENSDART00000166174
si:ch73-252i11.1
chr21_-_39931285 0.64 ENSDART00000180010
ENSDART00000024407
transmembrane and immunoglobulin domain containing 1
chr19_-_35035857 0.63 ENSDART00000103253
bone morphogenetic protein 8a
chr4_-_8040436 0.63 ENSDART00000113033
si:ch211-240l19.6
chr9_+_24121036 0.62 ENSDART00000101565
matrix AAA peptidase interacting protein 1
chr2_-_37888429 0.61 ENSDART00000183277
mannose binding lectin 2
chr8_+_27555314 0.61 ENSDART00000135568
ENSDART00000016696
ras homolog family member Cb
chr6_+_42918933 0.61 ENSDART00000064896
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr17_+_5976683 0.61 ENSDART00000110276
zgc:194275
chr15_-_29326254 0.61 ENSDART00000114492
si:dkey-52l18.4
chr6_+_40775800 0.59 ENSDART00000085090
si:ch211-157b11.8
chr13_-_46991577 0.58 ENSDART00000114748
vasoactive intestinal peptide
chr8_+_13849999 0.58 ENSDART00000143784
double C2-like domains, delta
chr7_-_5640822 0.58 ENSDART00000143767

chr11_+_34921492 0.58 ENSDART00000128070
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr5_-_15494164 0.57 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr7_-_50367326 0.57 ENSDART00000141926
protein regulator of cytokinesis 1b
chr14_+_22297257 0.56 ENSDART00000113676
ATPase phospholipid transporting 10B
chr13_+_40770628 0.56 ENSDART00000085846
NK1 transcription factor related 2-like,a
chr21_+_33172526 0.56 ENSDART00000183532
ADP-ribosylation factor-like 3, like 1
chr3_+_14641962 0.56 ENSDART00000091070
zgc:158403
chr21_+_34981263 0.56 ENSDART00000132711
RNA binding motif protein 11
chr11_+_7264457 0.56 ENSDART00000154182
receptor accessory protein 6
chr12_-_26415499 0.56 ENSDART00000185779
synaptopodin 2-like b
chr19_-_31341850 0.56 ENSDART00000040810
ADP-ribosylation factor-like 4ab
chr7_+_58751504 0.55 ENSDART00000024185
zgc:56231
chr13_+_24834199 0.55 ENSDART00000101274
zgc:153981
chr12_-_13336703 0.55 ENSDART00000134356
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_55423220 0.54 ENSDART00000158929
cathepsin A
chr7_+_33279618 0.54 ENSDART00000173706
coronin, actin binding protein, 2Ba
chr21_-_25774605 0.53 ENSDART00000002128
zgc:112437
chr4_-_16001118 0.52 ENSDART00000041070
ENSDART00000125389
mesoderm specific transcript
chr1_-_1894722 0.52 ENSDART00000165669
si:ch211-132g1.3
chr19_-_10612774 0.51 ENSDART00000091898
si:dkey-211g8.6
chr12_-_4301234 0.51 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr22_-_5006801 0.50 ENSDART00000106166
retinal homeobox gene 1
chr14_-_7409364 0.50 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr14_+_22172047 0.50 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr25_-_24240797 0.49 ENSDART00000132790
SPT2 chromatin protein domain containing 1
chr7_+_57089354 0.49 ENSDART00000140702
secretory carrier membrane protein 2, like
chr2_-_50225411 0.47 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr14_+_34514336 0.47 ENSDART00000024440
forkhead box I3b
chr6_-_33129045 0.47 ENSDART00000073757
tetraspanin 1
chr24_+_8736497 0.47 ENSDART00000181904
transmembrane protein 14Ca
chr21_+_30351256 0.47 ENSDART00000078341
forkhead box I3a
chr25_+_27744293 0.47 ENSDART00000103519
ENSDART00000149456
Wiskott-Aldrich syndrome-like a
chr8_-_13029297 0.46 ENSDART00000144305
DENN/MADD domain containing 2Da
chr5_-_69212184 0.46 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr23_-_1583193 0.46 ENSDART00000143841
fibronectin type III domain containing 7b
chr17_-_15777350 0.46 ENSDART00000155711
ankyrin repeat domain 6a
chr20_+_21391181 0.46 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jagged 2b
chr5_-_29152457 0.45 ENSDART00000078469
NADPH oxidase activator 1
chr15_+_33989181 0.45 ENSDART00000169487
von Willebrand factor D and EGF domains
chr20_+_36623807 0.45 ENSDART00000149171
ENSDART00000062895
signal recognition particle 9
chr2_+_34967022 0.44 ENSDART00000134926
astrotactin 1
chr8_-_14554785 0.44 ENSDART00000057645
quiescin Q6 sulfhydryl oxidase 1
chr6_+_49028874 0.44 ENSDART00000175254
solute carrier family 16 (monocarboxylate transporter), member 1a
chr1_-_53468160 0.44 ENSDART00000143349
zgc:66455
chr8_-_11229523 0.44 ENSDART00000002164
unc-45 myosin chaperone B
chr2_+_34967210 0.43 ENSDART00000141796
astrotactin 1
chr21_+_27336550 0.43 ENSDART00000139634
dipeptidyl-peptidase 3
chr16_+_54875530 0.43 ENSDART00000149795
nuclear receptor subfamily 0, group B, member 2a
chr1_+_594584 0.42 ENSDART00000135944
junctional adhesion molecule 2a
chr25_-_9013963 0.42 ENSDART00000073912
recombination activating gene 2
chr5_-_25572151 0.42 ENSDART00000144995
si:dkey-229d2.4
chr6_-_8360918 0.42 ENSDART00000004716
acid phosphatase 5a, tartrate resistant
chr14_+_2487672 0.42 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr20_-_43743700 0.41 ENSDART00000100620
si:dkeyp-50f7.2
chr22_+_7439186 0.41 ENSDART00000190667
zgc:92041
chr9_+_50749388 0.41 ENSDART00000181015
fidgetin
chr7_+_69841017 0.41 ENSDART00000169107

chr21_-_25522510 0.41 ENSDART00000162711
connector enhancer of kinase suppressor of Ras 2b
chr14_-_33277743 0.41 ENSDART00000048130
START domain containing 14
chr15_+_38299385 0.40 ENSDART00000142403
si:dkey-24p1.6
chr19_-_9711472 0.40 ENSDART00000016197
ENSDART00000175075
solute carrier family 2 (facilitated glucose transporter), member 3a
chr3_+_36515376 0.40 ENSDART00000161652
si:dkeyp-72e1.9
chr4_+_5255041 0.40 ENSDART00000137966
coiled-coil domain containing 167
chr15_+_24572926 0.40 ENSDART00000155636
ENSDART00000187800
dehydrogenase/reductase (SDR family) member 13b
chr23_-_19831739 0.40 ENSDART00000125066
HAUS augmin-like complex, subunit 7
chr16_-_42066523 0.40 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr12_+_30705769 0.39 ENSDART00000186448
ENSDART00000066259
potassium channel, subfamily K, member 1a
chr5_-_22052852 0.39 ENSDART00000002938
myotubularin related protein 8
chr24_+_35564668 0.39 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr23_+_4741543 0.39 ENSDART00000144761
Raf-1 proto-oncogene, serine/threonine kinase a
chr8_+_44358443 0.39 ENSDART00000189130
ENSDART00000189212

chr20_+_18703454 0.39 ENSDART00000152342
eukaryotic translation initiation factor 5
chr7_-_20836625 0.39 ENSDART00000192566
claudin 15a
chr20_-_39188476 0.38 ENSDART00000152858
regulator of calcineurin 2
chr10_-_38468847 0.38 ENSDART00000133914
glycerophosphodiester phosphodiesterase domain containing 5a
chr6_+_50452699 0.38 ENSDART00000115049
myelocytomatosis oncogene homolog
chr19_-_27542433 0.38 ENSDART00000136414
si:ch211-152p11.4
chr25_-_34632050 0.38 ENSDART00000170671
multiple EGF-like-domains 8
chr4_-_12978925 0.38 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr18_+_8402129 0.37 ENSDART00000081154
ENSDART00000171974
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr12_+_30706158 0.37 ENSDART00000133869
potassium channel, subfamily K, member 1a
chr10_-_31805923 0.36 ENSDART00000077785
vacuolar protein sorting 26 homolog B, like
chr23_-_26532696 0.36 ENSDART00000124811
ENSDART00000180274
si:dkey-205h13.2
chr13_+_24584401 0.36 ENSDART00000057599
fucose mutarotase
chr15_-_23761580 0.36 ENSDART00000137918
BCL2 binding component 3
chr14_-_33278084 0.35 ENSDART00000132850
START domain containing 14
chr8_-_22273819 0.35 ENSDART00000121513
nephronophthisis 4
chr17_-_8692722 0.35 ENSDART00000148931
ENSDART00000192891
C-terminal binding protein 2a
chr11_-_5865744 0.34 ENSDART00000104360
guanidinoacetate N-methyltransferase
chr6_-_41135215 0.34 ENSDART00000001861
solute carrier family 6 member 22, tandem duplicate 1
chr11_+_31730680 0.34 ENSDART00000145497
diaphanous-related formin 3
chr5_-_37900350 0.34 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr3_-_32169754 0.34 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr8_+_14158021 0.34 ENSDART00000080832
si:dkey-6n6.2
chr23_+_30985530 0.33 ENSDART00000142953
si:ch211-197l9.2
chr5_+_58679071 0.33 ENSDART00000019561
zgc:171734
chr23_-_15090782 0.33 ENSDART00000133624
si:ch211-218g4.2
chr1_-_59141715 0.33 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr18_+_34861568 0.33 ENSDART00000192825

chr16_+_32152612 0.33 ENSDART00000008880
G protein-coupled receptor, class C, group 6, member A
chr20_+_46371458 0.33 ENSDART00000152912
adhesion G protein-coupled receptor G11
chr7_+_4524059 0.33 ENSDART00000187693
si:dkey-83f18.4
chr6_+_11438972 0.32 ENSDART00000029314
collagen, type V, alpha 2b
chr6_-_12644563 0.32 ENSDART00000153797
dedicator of cytokinesis 9b
chr11_-_30352333 0.32 ENSDART00000030794
transmembrane protein 169a
chr23_+_9522942 0.32 ENSDART00000137751
oxysterol binding protein-like 2b
chr5_+_40485503 0.32 ENSDART00000051055
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr4_+_10066840 0.31 ENSDART00000026492
filamin C, gamma b (actin binding protein 280)
chr18_+_7345417 0.31 ENSDART00000041429
GLI pathogenesis-related 1b
chr17_-_25331439 0.31 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr19_-_34927201 0.31 ENSDART00000076518
Src-like-adaptor 1
chr10_-_25217347 0.31 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr22_-_18546649 0.31 ENSDART00000171277
cold inducible RNA binding protein b
chr15_-_34878388 0.31 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr23_+_21479958 0.31 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
chr13_-_438705 0.30 ENSDART00000082142

chr6_-_33129312 0.30 ENSDART00000156987
tetraspanin 1
chr2_-_1227221 0.30 ENSDART00000130897
ATP binding cassette subfamily F member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0090008 hypoblast development(GO:0090008)
0.4 1.2 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.9 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 1.2 GO:0010269 response to selenium ion(GO:0010269)
0.2 0.8 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.2 1.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 0.5 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.6 GO:0033605 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.2 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.1 0.7 GO:0070254 mucus secretion(GO:0070254)
0.1 0.6 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.8 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 2.3 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.7 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.3 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.7 GO:0030104 water homeostasis(GO:0030104)
0.1 0.4 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.4 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 1.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.7 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 1.0 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.7 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 2.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.4 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 1.0 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.4 GO:0045453 bone resorption(GO:0045453)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354)
0.0 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 1.2 GO:0014029 neural crest formation(GO:0014029)
0.0 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.0 0.1 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.5 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.1 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.7 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.5 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.4 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.6 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 0.5 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.2 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 0.4 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 2.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.3 GO:0005771 multivesicular body(GO:0005771)
0.1 0.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 1.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 0.6 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.7 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.0 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.4 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 2.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 1.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.5 GO:0005179 hormone activity(GO:0005179)
0.0 2.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 2.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.7 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.7 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation