ISMARA results: etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa

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PRJEB1986: zebrafish developmental stages transcriptome

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Results for etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Z-value: 6.17

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Transcription factors associated with etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Gene Symbol	Gene ID	Gene Info
etv5b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000044511	ETS variant transcription factor 5b
etv5a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000069763	ETS variant transcription factor 5a
etv5a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000113729	ETS variant transcription factor 5a
etv5b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000113744	ETS variant transcription factor 5b
elk1 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000078066	ETS transcription factor ELK1
elk4 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000077092	ETS transcription factor ELK4
etv1 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000101959	ETS variant transcription factor 1
elf1 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000020759	E74-like ETS transcription factor 1
erfl3 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000062801	Ets2 repressor factor like 3
erf NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000063417	Ets2 repressor factor
gabpa NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000069289	GA binding protein transcription factor subunit alpha
gabpa NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000110923	GA binding protein transcription factor subunit alpha
elk3 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000018688	ETS transcription factor ELK3
elk3 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000110853	ETS transcription factor ELK3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
etv1	dr11_v1_chr15_-_34214440_34214440	-0.94	1.8e-09	Click!
gabpa	dr11_v1_chr9_+_35016201_35016201	0.93	5.2e-09	Click!
elk1	dr11_v1_chr8_+_8735285_8735285	-0.92	2.3e-08	Click!
etv5a	dr11_v1_chr9_+_22632126_22632126	-0.80	4.0e-05	Click!
elk3	dr11_v1_chr4_+_7677318_7677318	0.78	8.4e-05	Click!
elk4	dr11_v1_chr11_-_38492564_38492564	-0.73	4.3e-04	Click!
etv5b	dr11_v1_chr6_-_14040136_14040161	0.69	1.0e-03	Click!
erf	dr11_v1_chr19_-_6193067_6193141	0.68	1.3e-03	Click!
elf1	dr11_v1_chr14_-_40821411_40821411	-0.47	4.4e-02	Click!
erfl3	dr11_v1_chr16_+_11029762_11029762	-0.44	6.2e-02	Click!

Activity profile of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Sorted Z-values of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_-_36554675 Show fit	25.02	ENSDART00000132804 ENSDART00000078746	ccdc157 NCBI UniProt ZFIN ENSEMBL Google Show fit	coiled-coil domain containing 157
chr4_+_12031958 Show fit	21.26	ENSDART00000044154	tnnt2c NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin T2c, cardiac
chr8_-_41228530 Show fit	19.42	ENSDART00000165949 ENSDART00000173055	fahd2a NCBI UniProt ZFIN ENSEMBL Google Show fit	fumarylacetoacetate hydrolase domain containing 2A
chr13_-_33700461 Show fit	15.28	ENSDART00000160520	mad2l1bp NCBI UniProt ZFIN ENSEMBL Google Show fit	MAD2L1 binding protein
chr8_+_48943009 Show fit	14.93	ENSDART00000180763	rer1 NCBI UniProt ZFIN ENSEMBL Google Show fit	retention in endoplasmic reticulum sorting receptor 1
chr25_+_186583 Show fit	14.86	ENSDART00000161504	pclaf NCBI UniProt ZFIN ENSEMBL Google Show fit	PCNA clamp associated factor
chr5_+_28497956 Show fit	14.76	ENSDART00000191935	nfr NCBI UniProt ZFIN ENSEMBL Google Show fit	notochord formation related
chr1_-_21723329 Show fit	14.55	ENSDART00000137138	si:ch211-134c9.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-134c9.2
chr20_+_13141408 Show fit	14.42	ENSDART00000034098	dtl NCBI UniProt ZFIN ENSEMBL Google Show fit	denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr13_+_15933168 Show fit	14.33	ENSDART00000131390	fignl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	fidgetin-like 1
chr25_-_19574146 Show fit	14.04	ENSDART00000156811	si:ch211-59o9.10 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-59o9.10
chr12_-_49151326 Show fit	13.55	ENSDART00000153244	bub3 NCBI UniProt ZFIN ENSEMBL Google Show fit	BUB3 mitotic checkpoint protein
chr14_-_14687004 Show fit	13.38	ENSDART00000169970	gcna NCBI UniProt ZFIN ENSEMBL Google Show fit	germ cell nuclear acidic peptidase
chr11_-_16115804 Show fit	13.27	ENSDART00000143436 ENSDART00000157928	rpf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosome production factor 1 homolog
chr12_+_10443785 Show fit	13.22	ENSDART00000029133	snu13b NCBI UniProt ZFIN ENSEMBL Google Show fit	SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr16_+_20294976 Show fit	13.16	ENSDART00000059619	fkbp14 NCBI UniProt ZFIN ENSEMBL Google Show fit	FK506 binding protein 14
chr18_+_29898955 Show fit	13.16	ENSDART00000064080	cenpn NCBI UniProt ZFIN ENSEMBL Google Show fit	centromere protein N
chr7_+_756942 Show fit	12.56	ENSDART00000152224	zgc:63470 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:63470
chr5_-_56119028 Show fit	12.54	ENSDART00000083134	mks1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Meckel syndrome, type 1
chr9_+_426392 Show fit	12.53	ENSDART00000172515	bzw1b NCBI UniProt ZFIN ENSEMBL Google Show fit	basic leucine zipper and W2 domains 1b
chr7_+_55518519 Show fit	12.49	ENSDART00000098476 ENSDART00000149915	cdt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	chromatin licensing and DNA replication factor 1
chr14_-_31618243 Show fit	12.44	ENSDART00000016592	mmgt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane magnesium transporter 1
chr5_+_69733096 Show fit	12.42	ENSDART00000169013	arl6ip4 NCBI UniProt ZFIN ENSEMBL Google Show fit	ADP-ribosylation factor-like 6 interacting protein 4
chr3_-_14498295 Show fit	12.39	ENSDART00000172102	elof1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ELF1 homolog, elongation factor 1
chr5_+_3927989 Show fit	12.32	ENSDART00000030125	znhit3 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger, HIT-type containing 3
chr5_-_67365006 Show fit	12.26	ENSDART00000136116	unga NCBI UniProt ZFIN ENSEMBL Google Show fit	uracil DNA glycosylase a
chr22_-_28373698 Show fit	11.83	ENSDART00000157592	si:ch211-213c4.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-213c4.5
chr13_-_29980215 Show fit	11.55	ENSDART00000042049	hif1an NCBI UniProt ZFIN ENSEMBL Google Show fit	hypoxia inducible factor 1, alpha subunit inhibitor
chr7_-_57637779 Show fit	11.40	ENSDART00000028017	mad2l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_-_51998708 Show fit	11.25	ENSDART00000097194	serinc5 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine incorporator 5
chr4_+_58576146 Show fit	11.22	ENSDART00000164911	si:ch211-212k5.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-212k5.4
chr20_-_33497128 Show fit	11.21	ENSDART00000101974	erh NCBI UniProt ZFIN ENSEMBL Google Show fit	enhancer of rudimentary homolog (Drosophila)
chr8_+_36554816 Show fit	11.20	ENSDART00000126687	sf3a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	splicing factor 3a, subunit 1
chr23_-_13840433 Show fit	11.19	ENSDART00000104831	naa10 NCBI UniProt ZFIN ENSEMBL Google Show fit	N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr21_-_30408775 Show fit	11.10	ENSDART00000101037	nhp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	NHP2 ribonucleoprotein homolog (yeast)
chr4_+_9592486 Show fit	11.08	ENSDART00000080829	hspa14 NCBI UniProt ZFIN ENSEMBL Google Show fit	heat shock protein 14
chr21_-_45840341 Show fit	11.03	ENSDART00000006942	irf1b NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 1b
chr14_-_10617923 Show fit	10.88	ENSDART00000133723 ENSDART00000131939 ENSDART00000136649	si:dkey-92i17.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-92i17.2
chr18_-_26797723 Show fit	10.79	ENSDART00000008013	sec11a NCBI UniProt ZFIN ENSEMBL Google Show fit	SEC11 homolog A, signal peptidase complex subunit
chr13_+_41917606 Show fit	10.71	ENSDART00000114741	polr1b NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (RNA) I polypeptide B
chr22_-_10752471 Show fit	10.63	ENSDART00000081191	sass6 NCBI UniProt ZFIN ENSEMBL Google Show fit	SAS-6 centriolar assembly protein
chr16_+_52966812 Show fit	10.57	ENSDART00000148435 ENSDART00000049099 ENSDART00000150117	trip13 NCBI UniProt ZFIN ENSEMBL Google Show fit	thyroid hormone receptor interactor 13
chr2_-_8688759 Show fit	10.54	ENSDART00000010257	miga1 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitoguardin 1
chr24_-_36175365 Show fit	10.51	ENSDART00000065338	pak1ip1 NCBI UniProt ZFIN ENSEMBL Google Show fit	PAK1 interacting protein 1
chr18_-_3552414 Show fit	10.48	ENSDART00000163762 ENSDART00000165434 ENSDART00000161197 ENSDART00000166841 ENSDART00000170260	dcun1d5 NCBI UniProt ZFIN ENSEMBL Google Show fit	DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr7_+_32693890 Show fit	10.44	ENSDART00000121972	slc39a13 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 39 (zinc transporter), member 13
chr20_-_14462995 Show fit	10.38	ENSDART00000152418 ENSDART00000044125	grcc10 NCBI UniProt ZFIN ENSEMBL Google Show fit	gene rich cluster, C10 gene
chr2_+_38055529 Show fit	10.27	ENSDART00000145642	si:rp71-1g18.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:rp71-1g18.1
chr3_+_59880317 Show fit	10.19	ENSDART00000166922 ENSDART00000108647	alyref NCBI UniProt ZFIN ENSEMBL Google Show fit	Aly/REF export factor
chr18_-_7056702 Show fit	10.13	ENSDART00000127397 ENSDART00000148774	utp15 NCBI UniProt ZFIN ENSEMBL Google Show fit	utp15, U3 small nucleolar ribonucleoprotein, homolog
chr8_-_17184482 Show fit	10.10	ENSDART00000025803	pola2 NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (DNA directed), alpha 2
chr12_-_34435604 Show fit	10.05	ENSDART00000115088	birc5a NCBI UniProt ZFIN ENSEMBL Google Show fit	baculoviral IAP repeat containing 5a
chr19_+_3206263 Show fit	9.97	ENSDART00000020344	zgc:86598 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:86598
chr16_-_54498109 Show fit	9.96	ENSDART00000083713	clk2b NCBI UniProt ZFIN ENSEMBL Google Show fit	CDC-like kinase 2b
chr2_+_30182431 Show fit	9.95	ENSDART00000004903	rdh10b NCBI UniProt ZFIN ENSEMBL Google Show fit	retinol dehydrogenase 10b
chr21_-_226071 Show fit	9.94	ENSDART00000160667	nup54 NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleoporin 54
chr25_+_3549401 Show fit	9.90	ENSDART00000166312	ccdc77 NCBI UniProt ZFIN ENSEMBL Google Show fit	coiled-coil domain containing 77
chr14_+_4276394 Show fit	9.88	ENSDART00000038301	gnpda2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glucosamine-6-phosphate deaminase 2
chr11_-_36230146 Show fit	9.78	ENSDART00000135888 ENSDART00000189782	rrp9 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr4_+_9536860 Show fit	9.72	ENSDART00000130083	lsm8 NCBI UniProt ZFIN ENSEMBL Google Show fit	LSM8 homolog, U6 small nuclear RNA associated
chr12_-_28363111 Show fit	9.70	ENSDART00000016283 ENSDART00000164156	psmd11b NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome 26S subunit, non-ATPase 11b
chr15_-_14064302 Show fit	9.69	ENSDART00000156384	BX927244.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr19_-_34089205 Show fit	9.67	ENSDART00000163618 ENSDART00000161666	rp9 NCBI UniProt ZFIN ENSEMBL Google Show fit	RP9, pre-mRNA splicing factor
chr5_-_67365750 Show fit	9.63	ENSDART00000062359	unga NCBI UniProt ZFIN ENSEMBL Google Show fit	uracil DNA glycosylase a
chr19_-_37508571 Show fit	9.62	ENSDART00000018255	ilf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin enhancer binding factor 2
chr20_-_2619316 Show fit	9.60	ENSDART00000185777	bub1 NCBI UniProt ZFIN ENSEMBL Google Show fit	BUB1 mitotic checkpoint serine/threonine kinase
chr5_-_67365333 Show fit	9.59	ENSDART00000133438	unga NCBI UniProt ZFIN ENSEMBL Google Show fit	uracil DNA glycosylase a
chr4_-_330748 Show fit	9.53	ENSDART00000067488	mrps10 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial ribosomal protein S10
chr15_-_43625549 Show fit	9.47	ENSDART00000168589	ctsc NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin C
chr22_+_10752787 Show fit	9.35	ENSDART00000186542	lsm7 NCBI UniProt ZFIN ENSEMBL Google Show fit	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr17_+_43013171 Show fit	9.20	ENSDART00000055541	gskip NCBI UniProt ZFIN ENSEMBL Google Show fit	gsk3b interacting protein
chr2_+_8649293 Show fit	9.13	ENSDART00000081442 ENSDART00000186024	fubp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	far upstream element (FUSE) binding protein 1
chr22_+_10752511 Show fit	9.12	ENSDART00000081188	lsm7 NCBI UniProt ZFIN ENSEMBL Google Show fit	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr5_-_3927692 Show fit	9.11	ENSDART00000146840 ENSDART00000058346	c1qbp NCBI UniProt ZFIN ENSEMBL Google Show fit	complement component 1, q subcomponent binding protein
chr23_-_31403668 Show fit	9.10	ENSDART00000147498	CR759830.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr9_-_30555725 Show fit	9.03	ENSDART00000079222	chaf1b NCBI UniProt ZFIN ENSEMBL Google Show fit	chromatin assembly factor 1, subunit B
chr21_-_26715270 Show fit	9.02	ENSDART00000053794	banf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	barrier to autointegration factor 1
chr21_+_17016337 Show fit	8.99	ENSDART00000065755	gpn3 NCBI UniProt ZFIN ENSEMBL Google Show fit	GPN-loop GTPase 3
chr9_+_48819280 Show fit	8.99	ENSDART00000112555	spc25 NCBI UniProt ZFIN ENSEMBL Google Show fit	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr19_+_34742706 Show fit	8.95	ENSDART00000103276	fam206a NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 206, member A
chr20_-_42972599 Show fit	8.94	ENSDART00000100751	pomcb NCBI UniProt ZFIN ENSEMBL Google Show fit	proopiomelanocortin b
chr13_+_33655404 Show fit	8.84	ENSDART00000023379	mgme1 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial genome maintenance exonuclease 1
chr2_-_32512648 Show fit	8.79	ENSDART00000170674	abcf2a NCBI UniProt ZFIN ENSEMBL Google Show fit	ATP-binding cassette, sub-family F (GCN20), member 2a
chr19_-_18855513 Show fit	8.77	ENSDART00000162708	ppt2 NCBI UniProt ZFIN ENSEMBL Google Show fit	palmitoyl-protein thioesterase 2
chr3_-_36602069 Show fit	8.77	ENSDART00000165414	rrn3 NCBI UniProt ZFIN ENSEMBL Google Show fit	RRN3 homolog, RNA polymerase I transcription factor
chr6_-_10725847 Show fit	8.74	ENSDART00000184567	sp3b NCBI UniProt ZFIN ENSEMBL Google Show fit	Sp3b transcription factor
chr15_-_14642186 Show fit	8.69	ENSDART00000164166	si:dkey-260j18.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-260j18.2
chr13_+_9559461 Show fit	8.66	ENSDART00000047740	wdr32 NCBI UniProt ZFIN ENSEMBL Google Show fit	WD repeat domain 32
chr23_-_7052362 Show fit	8.55	ENSDART00000127702 ENSDART00000192468	prpf6 NCBI UniProt ZFIN ENSEMBL Google Show fit	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr7_-_30177691 Show fit	8.53	ENSDART00000046689	tmed3 NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane p24 trafficking protein 3
chr3_-_27065477 Show fit	8.53	ENSDART00000185660	atf7ip2 NCBI UniProt ZFIN ENSEMBL Google Show fit	activating transcription factor 7 interacting protein 2
chr19_-_34742440 Show fit	8.52	ENSDART00000122625 ENSDART00000175621	elp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	elongator acetyltransferase complex subunit 2
chr7_+_38744924 Show fit	8.49	ENSDART00000052329	znf408 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger protein 408
chr25_+_3549841 Show fit	8.44	ENSDART00000164030	ccdc77 NCBI UniProt ZFIN ENSEMBL Google Show fit	coiled-coil domain containing 77
chr22_-_621888 Show fit	8.42	ENSDART00000135829	srsf3b NCBI UniProt ZFIN ENSEMBL Google Show fit	serine/arginine-rich splicing factor 3b
chr5_+_51833132 Show fit	8.41	ENSDART00000167491	papd4 NCBI UniProt ZFIN ENSEMBL Google Show fit	PAP associated domain containing 4
chr4_+_13931578 Show fit	8.27	ENSDART00000142466	pphln1 NCBI UniProt ZFIN ENSEMBL Google Show fit	periphilin 1
chr21_-_25213616 Show fit	8.23	ENSDART00000122513	rfc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	replication factor C (activator 1) 2
chr22_-_5655680 Show fit	8.19	ENSDART00000159629	mcm2 NCBI UniProt ZFIN ENSEMBL Google Show fit	minichromosome maintenance complex component 2
chr9_-_12269847 Show fit	8.19	ENSDART00000136558 ENSDART00000144734 ENSDART00000131766 ENSDART00000032344	nup35 NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleoporin 35
chr20_-_37820939 Show fit	8.16	ENSDART00000032978	nsl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	NSL1, MIS12 kinetochore complex component
chr8_+_387622 Show fit	8.15	ENSDART00000167361	pym1 NCBI UniProt ZFIN ENSEMBL Google Show fit	PYM homolog 1, exon junction complex associated factor
chr6_+_41808673 Show fit	8.09	ENSDART00000038163	rad18 NCBI UniProt ZFIN ENSEMBL Google Show fit	RAD18 E3 ubiquitin protein ligase
chr5_+_68826514 Show fit	8.06	ENSDART00000061406	usp39 NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin specific peptidase 39
chr6_+_49095646 Show fit	7.97	ENSDART00000103385	slc25a55a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 25, member 55a
chr13_-_24396199 Show fit	7.90	ENSDART00000181093	tbp NCBI UniProt ZFIN ENSEMBL Google Show fit	TATA box binding protein
chr23_-_44871987 Show fit	7.88	ENSDART00000085764	wu:fb72h05 NCBI UniProt ZFIN ENSEMBL Google Show fit	wu:fb72h05
chr7_-_16598212 Show fit	7.83	ENSDART00000128488	e2f8 NCBI UniProt ZFIN ENSEMBL Google Show fit	E2F transcription factor 8
chr3_-_61116258 Show fit	7.81	ENSDART00000009194 ENSDART00000156978	aimp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr16_+_33931032 Show fit	7.79	ENSDART00000167240	snip1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Smad nuclear interacting protein
chr19_+_7424347 Show fit	7.79	ENSDART00000004622	sf3b4 NCBI UniProt ZFIN ENSEMBL Google Show fit	splicing factor 3b, subunit 4
chr5_-_4297459 Show fit	7.77	ENSDART00000018895	srrt NCBI UniProt ZFIN ENSEMBL Google Show fit	serrate RNA effector molecule homolog (Arabidopsis)
chr21_-_30994577 Show fit	7.75	ENSDART00000065503	pgap2 NCBI UniProt ZFIN ENSEMBL Google Show fit	post-GPI attachment to proteins 2
chr15_+_30350061 Show fit	7.75	ENSDART00000135632 ENSDART00000044452	mrps23 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial ribosomal protein S23
chr12_-_7253270 Show fit	7.75	ENSDART00000035762	ube2d1b NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin-conjugating enzyme E2D 1b
chr12_+_20667301 Show fit	7.75	ENSDART00000144804	mxra7 NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix-remodelling associated 7
chr4_-_2265271 Show fit	7.69	ENSDART00000125815	krr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	KRR1, small subunit (SSU) processome component, homolog (yeast)
chr21_-_45878872 Show fit	7.57	ENSDART00000029763	sap30l NCBI UniProt ZFIN ENSEMBL Google Show fit	sap30-like
chr24_-_36196077 Show fit	7.52	ENSDART00000154395	esco1 NCBI UniProt ZFIN ENSEMBL Google Show fit	establishment of sister chromatid cohesion N-acetyltransferase 1
chr23_-_19715557 Show fit	7.41	ENSDART00000143764	rpl10 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L10
chr6_-_54433995 Show fit	7.39	ENSDART00000017230	snrpc NCBI UniProt ZFIN ENSEMBL Google Show fit	small nuclear ribonucleoprotein polypeptide C
chr5_-_26893310 Show fit	7.38	ENSDART00000126669	lman2lb NCBI UniProt ZFIN ENSEMBL Google Show fit	lectin, mannose-binding 2-like b
chr20_+_26892761 Show fit	7.38	ENSDART00000133293	ftr97 NCBI UniProt ZFIN ENSEMBL Google Show fit	finTRIM family, member 97
chr1_+_34685405 Show fit	7.36	ENSDART00000037986 ENSDART00000166007	gpalpp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	GPALPP motifs containing 1
chr2_+_1124512 Show fit	7.35	ENSDART00000108718	polr2d NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (RNA) II (DNA directed) polypeptide D
chr13_-_24396003 Show fit	7.34	ENSDART00000016211	tbp NCBI UniProt ZFIN ENSEMBL Google Show fit	TATA box binding protein
chr3_-_53559581 Show fit	7.33	ENSDART00000183499	notch3 NCBI UniProt ZFIN ENSEMBL Google Show fit	notch 3
chr6_+_29707129 Show fit	7.32	ENSDART00000023549 ENSDART00000164849	phb2b NCBI UniProt ZFIN ENSEMBL Google Show fit	prohibitin 2b
chr8_+_44613135 Show fit	7.31	ENSDART00000063392	lsm1 NCBI UniProt ZFIN ENSEMBL Google Show fit	LSM1, U6 small nuclear RNA associated
chr15_+_17343319 Show fit	7.29	ENSDART00000018461	vmp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	vacuole membrane protein 1
chr5_-_48070779 Show fit	7.28	ENSDART00000078401	tmem161b NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 161B
chr3_-_15444396 Show fit	7.24	ENSDART00000104361	si:dkey-56d12.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-56d12.4
chr18_-_35407289 Show fit	7.21	ENSDART00000012018	snrpa NCBI UniProt ZFIN ENSEMBL Google Show fit	small nuclear ribonucleoprotein polypeptide A
chr7_-_13906409 Show fit	7.20	ENSDART00000062257	slc39a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 39 (zinc transporter), member 1
chr13_+_24662238 Show fit	7.19	ENSDART00000014176	msx3 NCBI UniProt ZFIN ENSEMBL Google Show fit	muscle segment homeobox 3
chr17_+_45395846 Show fit	7.13	ENSDART00000058793	nenf NCBI UniProt ZFIN ENSEMBL Google Show fit	neudesin neurotrophic factor
chr20_-_10487951 Show fit	7.10	ENSDART00000064112	glrx5 NCBI UniProt ZFIN ENSEMBL Google Show fit	glutaredoxin 5 homolog (S. cerevisiae)
chr1_-_44581937 Show fit	7.09	ENSDART00000009858	tmx2b NCBI UniProt ZFIN ENSEMBL Google Show fit	thioredoxin-related transmembrane protein 2b
chr17_-_12966907 Show fit	7.08	ENSDART00000022874	psma6a NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit alpha 6a
chr7_+_22796723 Show fit	7.05	ENSDART00000077395 ENSDART00000146368	rbm4.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	RNA binding motif protein 4.2
chr12_-_20409794 Show fit	6.98	ENSDART00000077936	lcmt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine carboxyl methyltransferase 1
chr5_+_61862199 Show fit	6.94	ENSDART00000132452	sympk NCBI UniProt ZFIN ENSEMBL Google Show fit	symplekin
chr21_+_22738939 Show fit	6.90	ENSDART00000151342 ENSDART00000079145	arhgap42a NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 42a
chr12_-_13336703 Show fit	6.86	ENSDART00000134356	lsm5 NCBI UniProt ZFIN ENSEMBL Google Show fit	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr21_+_6136981 Show fit	6.86	ENSDART00000065859 ENSDART00000166287	cdk9 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin-dependent kinase 9 (CDC2-related kinase)
chr1_-_34685329 Show fit	6.85	ENSDART00000125944 ENSDART00000008277	pibf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	progesterone immunomodulatory binding factor 1
chr18_-_20458412 Show fit	6.85	ENSDART00000012241	kif23 NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 23
chr14_-_25935167 Show fit	6.83	ENSDART00000139855	g3bp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	GTPase activating protein (SH3 domain) binding protein 1
chr8_+_47677208 Show fit	6.83	ENSDART00000123254	dpp9 NCBI UniProt ZFIN ENSEMBL Google Show fit	dipeptidyl-peptidase 9
chr5_-_52010122 Show fit	6.82	ENSDART00000073627 ENSDART00000163898 ENSDART00000051003	cdk7 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin-dependent kinase 7
chr13_-_33654931 Show fit	6.80	ENSDART00000020350	snx5 NCBI UniProt ZFIN ENSEMBL Google Show fit	sorting nexin 5
chr18_-_20458840 Show fit	6.77	ENSDART00000177125	kif23 NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 23
chr18_-_35407530 Show fit	6.77	ENSDART00000137663	snrpa NCBI UniProt ZFIN ENSEMBL Google Show fit	small nuclear ribonucleoprotein polypeptide A
chr4_+_646154 Show fit	6.73	ENSDART00000171138	xpot NCBI UniProt ZFIN ENSEMBL Google Show fit	exportin, tRNA (nuclear export receptor for tRNAs)
chr6_+_40775800 Show fit	6.71	ENSDART00000085090	si:ch211-157b11.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-157b11.8
chr3_-_25275364 Show fit	6.71	ENSDART00000163782 ENSDART00000145420 ENSDART00000133718 ENSDART00000055492	ddx5 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_+_32490238 Show fit	6.68	ENSDART00000191839	ndor1 NCBI UniProt ZFIN ENSEMBL Google Show fit	NADPH dependent diflavin oxidoreductase 1
chr21_+_28502340 Show fit	6.68	ENSDART00000077897 ENSDART00000140229	otub1a NCBI UniProt ZFIN ENSEMBL Google Show fit	OTU deubiquitinase, ubiquitin aldehyde binding 1a
chr3_-_34816893 Show fit	6.68	ENSDART00000084448 ENSDART00000154696	psmd11a NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome 26S subunit, non-ATPase 11a
chr8_+_15277874 Show fit	6.67	ENSDART00000146965	dnttip2 NCBI UniProt ZFIN ENSEMBL Google Show fit	deoxynucleotidyltransferase, terminal, interacting protein 2
chr18_+_26429428 Show fit	6.66	ENSDART00000142686	blm NCBI UniProt ZFIN ENSEMBL Google Show fit	Bloom syndrome, RecQ helicase-like
chr8_+_47683539 Show fit	6.66	ENSDART00000190701	dpp9 NCBI UniProt ZFIN ENSEMBL Google Show fit	dipeptidyl-peptidase 9
chr23_+_37090889 Show fit	6.64	ENSDART00000074406	ubxn10 NCBI UniProt ZFIN ENSEMBL Google Show fit	UBX domain protein 10
chr11_-_287670 Show fit	6.62	ENSDART00000035737	slc11a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr16_+_26680508 Show fit	6.61	ENSDART00000142215 ENSDART00000159064	virma NCBI UniProt ZFIN ENSEMBL Google Show fit	vir like m6A methyltransferase associated
chr19_-_18855717 Show fit	6.59	ENSDART00000158192	ppt2 NCBI UniProt ZFIN ENSEMBL Google Show fit	palmitoyl-protein thioesterase 2
chr23_+_9560797 Show fit	6.54	ENSDART00000180014	adrm1 NCBI UniProt ZFIN ENSEMBL Google Show fit	adhesion regulating molecule 1
chr10_-_5135788 Show fit	6.51	ENSDART00000108587 ENSDART00000138537	sec31a NCBI UniProt ZFIN ENSEMBL Google Show fit	SEC31 homolog A, COPII coat complex component
chr13_+_23897975 Show fit	6.50	ENSDART00000002244	sf3b5 NCBI UniProt ZFIN ENSEMBL Google Show fit	splicing factor 3b, subunit 5
chr2_+_6243144 Show fit	6.50	ENSDART00000058258	gng5 NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein (G protein), gamma 5
chr13_-_35760969 Show fit	6.49	ENSDART00000127476	erlec1 NCBI UniProt ZFIN ENSEMBL Google Show fit	endoplasmic reticulum lectin 1
chr7_+_1505507 Show fit	6.48	ENSDART00000161015	nop10 NCBI UniProt ZFIN ENSEMBL Google Show fit	NOP10 ribonucleoprotein homolog (yeast)
chr18_-_35407695 Show fit	6.43	ENSDART00000191845 ENSDART00000141703	snrpa NCBI UniProt ZFIN ENSEMBL Google Show fit	small nuclear ribonucleoprotein polypeptide A
chr10_+_7671260 Show fit	6.41	ENSDART00000157608	fam136a NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 136, member A
chr4_-_18840919 Show fit	6.39	ENSDART00000015834	cbll1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr8_+_41229233 Show fit	6.38	ENSDART00000131135	zgc:152830 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:152830
chr12_-_2869565 Show fit	6.36	ENSDART00000152772	zdhhc16b NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger, DHHC-type containing 16b
chr8_+_23726708 Show fit	6.36	ENSDART00000142395	mkrn4 NCBI UniProt ZFIN ENSEMBL Google Show fit	makorin, ring finger protein, 4
chr19_-_29853402 Show fit	6.35	ENSDART00000024292 ENSDART00000188508	txlna NCBI UniProt ZFIN ENSEMBL Google Show fit	taxilin alpha
chr3_-_27066451 Show fit	6.27	ENSDART00000156228 ENSDART00000156311	atf7ip2 NCBI UniProt ZFIN ENSEMBL Google Show fit	activating transcription factor 7 interacting protein 2
chr2_+_2772447 Show fit	6.26	ENSDART00000124882	thoc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	THO complex 1
chr23_-_14216506 Show fit	6.26	ENSDART00000019620	ddx23 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr5_-_25733745 Show fit	6.25	ENSDART00000051566	zgc:101016 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:101016
chr7_+_71683853 Show fit	6.17	ENSDART00000163002	emilin2b NCBI UniProt ZFIN ENSEMBL Google Show fit	elastin microfibril interfacer 2b
chr1_-_51720633 Show fit	6.16	ENSDART00000045894	rnaseh2a NCBI UniProt ZFIN ENSEMBL Google Show fit	ribonuclease H2, subunit A
chr3_-_45777226 Show fit	6.14	ENSDART00000192849	h3f3b.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	H3 histone, family 3B.1
chr1_-_34685007 Show fit	6.13	ENSDART00000157471	klf5a NCBI UniProt ZFIN ENSEMBL Google Show fit	Kruppel-like factor 5a
chr21_-_30181732 Show fit	6.12	ENSDART00000015636	hnrnph1l NCBI UniProt ZFIN ENSEMBL Google Show fit	heterogeneous nuclear ribonucleoprotein H1, like
chr18_+_49248389 Show fit	6.12	ENSDART00000059285 ENSDART00000142004 ENSDART00000132751	yif1b NCBI UniProt ZFIN ENSEMBL Google Show fit	Yip1 interacting factor homolog B (S. cerevisiae)
chr22_+_9523479 Show fit	6.10	ENSDART00000189473 ENSDART00000143953	strip1 NCBI UniProt ZFIN ENSEMBL Google Show fit	striatin interacting protein 1
chr14_-_26465729 Show fit	6.07	ENSDART00000143454	syvn1 NCBI UniProt ZFIN ENSEMBL Google Show fit	synovial apoptosis inhibitor 1, synoviolin
chr19_-_43657468 Show fit	6.06	ENSDART00000150940	si:ch211-193k19.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-193k19.2
chr1_+_25650917 Show fit	6.05	ENSDART00000054235	plrg1 NCBI UniProt ZFIN ENSEMBL Google Show fit	pleiotropic regulator 1
chr18_-_21910991 Show fit	6.04	ENSDART00000089787 ENSDART00000169220 ENSDART00000132381 ENSDART00000191764	edc4 NCBI UniProt ZFIN ENSEMBL Google Show fit	enhancer of mRNA decapping 4
chr10_-_3427589 Show fit	6.04	ENSDART00000133452 ENSDART00000037183	tmed2 NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane p24 trafficking protein 2
chr20_-_29633507 Show fit	6.03	ENSDART00000040292	cpsf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	cleavage and polyadenylation specific factor 3
chr21_-_7781555 Show fit	6.02	ENSDART00000084380 ENSDART00000189131	aggf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	angiogenic factor with G patch and FHA domains 1
chr2_-_5723786 Show fit	6.01	ENSDART00000100924	cwc25 NCBI UniProt ZFIN ENSEMBL Google Show fit	CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr16_+_38337783 Show fit	6.00	ENSDART00000135008	gabpb2b NCBI UniProt ZFIN ENSEMBL Google Show fit	GA binding protein transcription factor, beta subunit 2b
chr20_-_16906623 Show fit	5.96	ENSDART00000012859 ENSDART00000171628	psma6b NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit alpha 6b

Network of associatons between targets according to the STRING database.

First level regulatory network of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.3	31.5	GO:0097510	base-excision repair, AP site formation via deaminated base removal(GO:0097510)
5.9	17.6	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
4.6	13.8	GO:0006041	glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
4.2	12.6	GO:1990403	embryonic brain development(GO:1990403)
3.6	10.8	GO:0035019	somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
3.5	24.2	GO:0040016	embryonic cleavage(GO:0040016)
3.3	9.9	GO:0090435	protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
3.3	13.2	GO:0033301	cell cycle comprising mitosis without cytokinesis(GO:0033301)
3.0	18.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
2.9	8.8	GO:0043504	mitochondrial DNA repair(GO:0043504)
2.8	19.7	GO:0006621	protein retention in ER lumen(GO:0006621)
2.6	10.6	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
2.5	7.5	GO:0034421	post-translational protein acetylation(GO:0034421)
2.4	19.1	GO:0072422	signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
2.4	11.8	GO:0097355	protein localization to heterochromatin(GO:0097355)
2.3	11.6	GO:0018197	peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
2.2	6.7	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
2.2	33.4	GO:0043248	proteasome assembly(GO:0043248)
2.2	15.2	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.0	30.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
2.0	5.9	GO:2000105	positive regulation of DNA-dependent DNA replication(GO:2000105)
1.9	5.8	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
1.8	12.4	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
1.8	12.3	GO:0000492	box C/D snoRNP assembly(GO:0000492)
1.8	8.8	GO:0031053	primary miRNA processing(GO:0031053)
1.8	8.8	GO:0019348	dolichol metabolic process(GO:0019348)
1.7	6.9	GO:0060043	regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
1.7	5.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
1.7	25.6	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
1.7	6.8	GO:0048211	Golgi vesicle docking(GO:0048211)
1.7	6.8	GO:0070129	regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
1.7	5.0	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
1.7	6.7	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
1.7	16.6	GO:0090329	regulation of DNA-dependent DNA replication(GO:0090329)
1.7	6.6	GO:0010039	response to iron ion(GO:0010039)
1.6	4.9	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.6	8.1	GO:0048855	adenohypophysis morphogenesis(GO:0048855)
1.6	6.4	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
1.6	1.6	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
1.6	4.7	GO:0021693	cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
1.5	13.9	GO:0006465	signal peptide processing(GO:0006465)
1.5	4.6	GO:0043576	respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
1.5	6.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.5	11.9	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
1.4	10.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
1.4	11.6	GO:0019405	alditol catabolic process(GO:0019405)
1.4	4.3	GO:0072344	rescue of stalled ribosome(GO:0072344)
1.4	4.3	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.4	5.6	GO:0051645	Golgi localization(GO:0051645)
1.4	11.1	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.4	4.1	GO:0000390	spliceosomal complex disassembly(GO:0000390)
1.4	12.3	GO:0006449	regulation of translational termination(GO:0006449)
1.4	4.1	GO:0006266	DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
1.3	13.5	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
1.3	17.5	GO:0002138	retinoic acid biosynthetic process(GO:0002138)
1.2	26.2	GO:0006301	postreplication repair(GO:0006301)
1.2	7.4	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
1.2	8.5	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
1.2	17.8	GO:0045116	protein neddylation(GO:0045116)
1.2	7.1	GO:1901314	regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
1.2	24.6	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
1.2	8.2	GO:1902292	cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
1.2	3.5	GO:0070734	histone H3-K27 methylation(GO:0070734)
1.2	4.7	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
1.2	1.2	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
1.1	4.6	GO:1903292	protein localization to Golgi membrane(GO:1903292)
1.1	3.4	GO:1903173	fatty alcohol metabolic process(GO:1903173)
1.1	2.2	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
1.1	4.4	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.1	4.4	GO:0006598	polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
1.1	27.1	GO:0006270	DNA replication initiation(GO:0006270)
1.0	3.1	GO:0001120	DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
1.0	6.0	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
1.0	3.0	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
1.0	2.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.0	7.8	GO:0051351	positive regulation of ligase activity(GO:0051351)
1.0	2.9	GO:0061355	Wnt protein secretion(GO:0061355)
1.0	11.5	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
1.0	2.9	GO:0001779	natural killer cell differentiation(GO:0001779)
0.9	28.4	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.9	10.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.9	20.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9	4.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.9	11.0	GO:0050688	regulation of defense response to virus(GO:0050688)
0.9	11.5	GO:0061055	myotome development(GO:0061055)
0.9	2.6	GO:0071033	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.9	10.4	GO:0009791	post-embryonic development(GO:0009791)
0.8	12.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.8	4.2	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.8	4.2	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.8	5.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.8	12.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.8	19.0	GO:0034508	centromere complex assembly(GO:0034508)
0.8	12.2	GO:0042026	protein refolding(GO:0042026)
0.8	8.1	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.8	12.8	GO:0008053	mitochondrial fusion(GO:0008053)
0.8	4.0	GO:0017006	protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.8	8.0	GO:0015813	acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.8	5.5	GO:0021982	pineal gland development(GO:0021982)
0.8	4.0	GO:0061056	sclerotome development(GO:0061056)
0.8	11.1	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.8	2.4	GO:0010586	miRNA metabolic process(GO:0010586)
0.8	1.5	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.8	3.8	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.7	5.2	GO:0035860	esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.7	5.2	GO:0003188	heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.7	2.2	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.7	1.4	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.7	7.8	GO:0034605	cellular response to heat(GO:0034605)
0.7	1.4	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.7	17.1	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.7	3.4	GO:0008216	spermidine metabolic process(GO:0008216)
0.7	2.0	GO:0021531	spinal cord radial glial cell differentiation(GO:0021531)
0.7	1.3	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.7	18.7	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.7	2.0	GO:0030237	female sex determination(GO:0030237)
0.7	5.3	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.7	2.0	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.6	6.9	GO:0060217	hemangioblast cell differentiation(GO:0060217)
0.6	1.8	GO:0051026	chiasma assembly(GO:0051026)
0.6	3.0	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.6	3.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.6	3.0	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.6	1.8	GO:0031591	wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.6	1.2	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442)
0.6	23.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.6	1.2	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.6	3.0	GO:0019370	leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.6	3.5	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.6	18.8	GO:0060030	dorsal convergence(GO:0060030)
0.6	3.5	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.6	18.3	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.6	1.7	GO:0036159	inner dynein arm assembly(GO:0036159)
0.6	10.7	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.6	3.3	GO:0046471	cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.5	56.4	GO:0006402	mRNA catabolic process(GO:0006402)
0.5	1.6	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5	5.9	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.5	6.4	GO:0006401	RNA catabolic process(GO:0006401)
0.5	9.6	GO:0050685	positive regulation of mRNA splicing, via spliceosome(GO:0048026) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.5	1.6	GO:0061400	positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.5	3.2	GO:0010269	response to selenium ion(GO:0010269)
0.5	1.6	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.5	6.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.5	15.0	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.5	14.6	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.5	1.5	GO:1990575	mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.5	4.4	GO:0007220	Notch receptor processing(GO:0007220)
0.5	2.9	GO:1905168	positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.5	1.4	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.5	167.4	GO:0008380	RNA splicing(GO:0008380)
0.5	5.7	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.5	1.4	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.5	2.7	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.5	6.9	GO:0009086	methionine biosynthetic process(GO:0009086)
0.5	4.6	GO:0006177	GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.5	1.4	GO:0036010	protein localization to endosome(GO:0036010)
0.5	6.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.5	5.4	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.5	2.3	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.4	1.3	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.4	3.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4	9.9	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.4	2.6	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.4	3.4	GO:0044528	regulation of mitochondrial mRNA stability(GO:0044528)
0.4	6.4	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.4	0.4	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.4	3.4	GO:1902038	positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.4	3.8	GO:0097345	mitochondrial outer membrane permeabilization(GO:0097345)
0.4	3.0	GO:0031057	negative regulation of histone modification(GO:0031057)
0.4	1.3	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4	7.0	GO:0015693	magnesium ion transport(GO:0015693)
0.4	1.2	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.4	4.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4	0.8	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.4	7.9	GO:0043631	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.4	21.3	GO:0006937	regulation of muscle contraction(GO:0006937)
0.4	0.4	GO:1904035	epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.4	1.2	GO:0048714	positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.4	4.3	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.4	6.8	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.4	7.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.4	1.9	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.4	1.5	GO:0019401	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4	3.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4	1.5	GO:0003400	regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.4	1.1	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.4	8.3	GO:1903322	positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.4	4.7	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.4	1.1	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.4	0.7	GO:0010893	positive regulation of steroid biosynthetic process(GO:0010893)
0.4	2.5	GO:0006172	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.3	1.7	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.3	13.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.3	1.4	GO:0016038	absorption of visible light(GO:0016038)
0.3	5.1	GO:0032392	DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.3	4.0	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.3	0.7	GO:0009188	ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.3	1.7	GO:0019388	galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.3	3.6	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.3	2.3	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.3	23.6	GO:0016072	rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.3	1.6	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.3	1.6	GO:0060231	mesenchymal to epithelial transition(GO:0060231)
0.3	1.3	GO:0070291	N-acylethanolamine metabolic process(GO:0070291)
0.3	2.5	GO:0031123	RNA 3'-end processing(GO:0031123)
0.3	1.6	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.3	12.9	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.3	0.9	GO:2000425	regulation of apoptotic cell clearance(GO:2000425)
0.3	0.6	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.3	1.2	GO:1903651	positive regulation of cytoplasmic transport(GO:1903651)
0.3	6.5	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.3	4.9	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.3	12.2	GO:0045766	positive regulation of angiogenesis(GO:0045766)
0.3	5.1	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.3	3.8	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.3	2.6	GO:2001239	histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.3	8.9	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3	1.1	GO:1990108	protein linear deubiquitination(GO:1990108)
0.3	4.1	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.3	2.7	GO:0031060	regulation of histone methylation(GO:0031060)
0.3	1.9	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.3	2.4	GO:0032486	Rap protein signal transduction(GO:0032486)
0.3	5.6	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.3	4.4	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.3	0.8	GO:1903358	regulation of Golgi organization(GO:1903358)
0.3	5.1	GO:0071218	response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.3	7.1	GO:0043049	otic placode formation(GO:0043049)
0.3	5.8	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.3	19.8	GO:0007030	Golgi organization(GO:0007030)
0.2	2.0	GO:0070933	histone H4 deacetylation(GO:0070933)
0.2	0.7	GO:0071480	response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2	1.2	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2	1.5	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.2	0.7	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2	4.6	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2	3.1	GO:0035518	histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.2	1.7	GO:0010830	regulation of myotube differentiation(GO:0010830) regulation of skeletal muscle fiber development(GO:0048742)
0.2	2.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.2	15.5	GO:0018210	peptidyl-threonine modification(GO:0018210)
0.2	1.9	GO:0036372	opsin transport(GO:0036372)
0.2	0.9	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.2	1.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.2	1.2	GO:0000012	single strand break repair(GO:0000012)
0.2	2.5	GO:0090398	cellular senescence(GO:0090398)
0.2	3.2	GO:0051452	vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2	3.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.2	1.3	GO:0018344	protein geranylgeranylation(GO:0018344)
0.2	0.7	GO:0097435	fibril organization(GO:0097435)
0.2	4.9	GO:0007520	myoblast fusion(GO:0007520)
0.2	1.9	GO:0006167	AMP biosynthetic process(GO:0006167)
0.2	5.6	GO:0048570	notochord morphogenesis(GO:0048570)
0.2	3.3	GO:0019827	stem cell population maintenance(GO:0019827)
0.2	0.6	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.2	2.0	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.2	3.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	5.6	GO:0016925	protein sumoylation(GO:0016925)
0.2	1.4	GO:0070073	regulation of melanocyte differentiation(GO:0045634) clustering of voltage-gated calcium channels(GO:0070073)
0.2	0.4	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2	7.9	GO:0030261	chromosome condensation(GO:0030261)
0.2	2.6	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2	10.6	GO:0010842	retina layer formation(GO:0010842)
0.2	0.4	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.2	3.3	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2	1.8	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.2	0.6	GO:0042560	10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2	4.9	GO:0042476	odontogenesis(GO:0042476)
0.2	3.6	GO:0016180	snRNA processing(GO:0016180)
0.2	0.7	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2	4.8	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	2.3	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.2	2.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.2	15.3	GO:0008033	tRNA processing(GO:0008033)
0.2	1.4	GO:0061647	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.2	2.0	GO:0035141	medial fin morphogenesis(GO:0035141)
0.2	9.5	GO:0042254	ribosome biogenesis(GO:0042254)
0.2	1.2	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2	3.8	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.2	0.6	GO:0032053	ciliary basal body organization(GO:0032053)
0.2	3.7	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.2	0.5	GO:0051030	snRNA transport(GO:0051030)
0.2	1.8	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	3.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2	0.8	GO:0071422	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.2	0.6	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2	0.9	GO:0043584	nose development(GO:0043584)
0.2	0.8	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.2	3.7	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.2	2.4	GO:0048264	determination of ventral identity(GO:0048264)
0.1	0.7	GO:0034982	protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.1	0.7	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.7	GO:0010867	regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.4	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.1	1.0	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	5.1	GO:0033500	carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.1	0.9	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1	0.6	GO:0061549	sympathetic ganglion development(GO:0061549)
0.1	0.7	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.1	6.4	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
0.1	5.5	GO:0010921	regulation of phosphatase activity(GO:0010921)
0.1	0.8	GO:0006004	fucose metabolic process(GO:0006004)
0.1	0.3	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	1.7	GO:0035476	angioblast cell migration(GO:0035476)
0.1	0.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	1.4	GO:0035844	cloaca development(GO:0035844)
0.1	0.9	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1	3.3	GO:0050821	protein stabilization(GO:0050821)
0.1	4.7	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1	1.8	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	1.7	GO:0046051	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.1	0.5	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	3.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.7	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	2.9	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.1	0.2	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1	0.6	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.1	3.0	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.1	2.6	GO:0035675	neuromast hair cell development(GO:0035675)
0.1	6.2	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	8.3	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.1	0.6	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	1.2	GO:0003209	cardiac atrium morphogenesis(GO:0003209)
0.1	2.8	GO:0021884	forebrain neuron development(GO:0021884)
0.1	1.3	GO:0014074	response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.1	0.2	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.1	2.1	GO:0006298	mismatch repair(GO:0006298)
0.1	0.6	GO:0018160	peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1	1.4	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	1.2	GO:0045580	regulation of T cell differentiation(GO:0045580)
0.1	0.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	3.1	GO:0060840	artery development(GO:0060840)
0.1	6.3	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.1	7.7	GO:0006457	protein folding(GO:0006457)
0.1	1.5	GO:0098781	ncRNA transcription(GO:0098781)
0.1	0.8	GO:0032096	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1	0.9	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	10.0	GO:0006397	mRNA processing(GO:0006397)
0.1	1.9	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell development(GO:0072015) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell development(GO:0072310) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.5	GO:0003308	desmosome assembly(GO:0002159) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1	0.3	GO:0043383	negative T cell selection(GO:0043383)
0.1	1.1	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	1.8	GO:0090307	mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1	6.2	GO:0055113	epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.1	1.3	GO:2001235	positive regulation of apoptotic signaling pathway(GO:2001235)
0.1	2.9	GO:0006612	protein targeting to membrane(GO:0006612)
0.1	1.5	GO:0071350	interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1	4.7	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.1	GO:0071156	regulation of cell cycle arrest(GO:0071156)
0.1	0.5	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	5.3	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.1	2.4	GO:0001946	lymphangiogenesis(GO:0001946)
0.1	2.0	GO:0035987	endodermal cell differentiation(GO:0035987)
0.1	0.6	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.1	GO:0033003	regulation of mast cell activation(GO:0033003)
0.1	0.2	GO:0051125	regulation of actin nucleation(GO:0051125)
0.1	0.3	GO:0043901	negative regulation of multi-organism process(GO:0043901) negative regulation of oocyte development(GO:0060283)
0.1	0.6	GO:0007530	sex determination(GO:0007530)
0.1	1.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.1	1.2	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1	0.3	GO:0051012	microtubule sliding(GO:0051012)
0.1	3.4	GO:0043297	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1	0.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	5.4	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.1	1.3	GO:0060046	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1	0.2	GO:0097094	craniofacial suture morphogenesis(GO:0097094) frontonasal suture morphogenesis(GO:0097095)
0.1	1.1	GO:0061300	cerebellum vasculature development(GO:0061300)
0.1	3.3	GO:0009306	protein secretion(GO:0009306)
0.1	2.9	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.1	0.3	GO:0060965	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	12.4	GO:0061371	determination of heart left/right asymmetry(GO:0061371)
0.1	1.5	GO:0003094	glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.1	1.1	GO:0060729	maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1	1.5	GO:0048263	determination of dorsal identity(GO:0048263)
0.1	2.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1	0.8	GO:0016926	protein desumoylation(GO:0016926)
0.1	1.8	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.1	3.0	GO:0045214	sarcomere organization(GO:0045214)
0.1	0.8	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	3.7	GO:0048484	enteric nervous system development(GO:0048484)
0.1	0.6	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.3	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.1	5.5	GO:0009615	response to virus(GO:0009615)
0.1	3.7	GO:0031101	fin regeneration(GO:0031101)
0.1	3.0	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1	0.9	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	7.9	GO:0030155	regulation of cell adhesion(GO:0030155)
0.1	3.3	GO:0045765	regulation of angiogenesis(GO:0045765)
0.1	1.5	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	3.3	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1	2.4	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	6.6	GO:0001755	neural crest cell migration(GO:0001755)
0.1	2.3	GO:0048565	digestive tract development(GO:0048565)
0.1	0.7	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.1	0.8	GO:0036065	fucosylation(GO:0036065)
0.1	0.2	GO:0003262	endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1	3.0	GO:0042738	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1	4.6	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.1	2.0	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.1	0.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	3.5	GO:0003341	cilium movement(GO:0003341)
0.1	1.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.5	GO:0061588	calcium activated phospholipid scrambling(GO:0061588)
0.1	0.6	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.1	0.8	GO:0060872	semicircular canal development(GO:0060872)
0.1	0.5	GO:0030308	negative regulation of cell growth(GO:0030308)
0.0	1.7	GO:0070121	Kupffer's vesicle development(GO:0070121)
0.0	0.3	GO:0072554	endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0	7.1	GO:0051301	cell division(GO:0051301)
0.0	1.5	GO:1903706	regulation of hemopoiesis(GO:1903706)
0.0	1.2	GO:0009145	purine nucleoside triphosphate biosynthetic process(GO:0009145) purine ribonucleoside triphosphate biosynthetic process(GO:0009206)
0.0	0.5	GO:0006767	water-soluble vitamin metabolic process(GO:0006767)
0.0	1.0	GO:0051961	negative regulation of neurogenesis(GO:0050768) negative regulation of nervous system development(GO:0051961)
0.0	0.4	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0	20.1	GO:0000278	mitotic cell cycle(GO:0000278)
0.0	0.9	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.8	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.8	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.3	GO:0031179	peptide modification(GO:0031179)
0.0	0.3	GO:0006477	protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0	0.6	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.7	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.2	GO:0032094	response to food(GO:0032094)
0.0	0.8	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	2.7	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.2	GO:0050779	RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0	0.2	GO:0019427	acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0	0.4	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.7	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.7	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0	2.4	GO:0070507	regulation of microtubule cytoskeleton organization(GO:0070507)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	6.3	GO:0045087	innate immune response(GO:0045087)
0.0	0.4	GO:0097061	dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	1.9	GO:0001817	regulation of cytokine production(GO:0001817)
0.0	0.4	GO:0032496	response to lipopolysaccharide(GO:0032496)
0.0	0.2	GO:0035627	ceramide transport(GO:0035627)
0.0	0.4	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0	2.5	GO:0043066	negative regulation of apoptotic process(GO:0043066)
0.0	1.5	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0060035	notochord cell development(GO:0060035) notochord cell vacuolation(GO:0060036)
0.0	1.2	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.2	GO:0097009	energy homeostasis(GO:0097009)
0.0	0.9	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
0.0	0.5	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.6	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	4.2	GO:0022604	regulation of cell morphogenesis(GO:0022604)
0.0	0.3	GO:0034284	response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0	0.3	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	2.4	GO:0006338	chromatin remodeling(GO:0006338)
0.0	1.3	GO:0021510	spinal cord development(GO:0021510)
0.0	0.4	GO:0060319	primitive erythrocyte differentiation(GO:0060319)
0.0	0.2	GO:0002183	cytoplasmic translational initiation(GO:0002183)
0.0	0.1	GO:2001057	reactive nitrogen species metabolic process(GO:2001057)
0.0	0.8	GO:0016575	histone deacetylation(GO:0016575)
0.0	1.1	GO:0009953	dorsal/ventral pattern formation(GO:0009953)
0.0	0.9	GO:0048916	posterior lateral line development(GO:0048916)
0.0	0.2	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	1.1	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.4	GO:0030593	neutrophil chemotaxis(GO:0030593) granulocyte chemotaxis(GO:0071621)
0.0	0.4	GO:0030500	regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0	0.2	GO:0006693	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	0.9	GO:0006414	translational elongation(GO:0006414)
0.0	0.1	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0	0.5	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.4	GO:0017148	negative regulation of translation(GO:0017148)
0.0	0.2	GO:1903286	positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.4	GO:0030814	regulation of cyclic nucleotide metabolic process(GO:0030799) regulation of cyclic nucleotide biosynthetic process(GO:0030802) regulation of nucleotide biosynthetic process(GO:0030808) regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of cyclase activity(GO:0031279) regulation of adenylate cyclase activity(GO:0045761) regulation of lyase activity(GO:0051339) regulation of purine nucleotide biosynthetic process(GO:1900371)
0.0	0.6	GO:0007043	cell-cell junction assembly(GO:0007043)
0.0	1.1	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.4	GO:0006396	RNA processing(GO:0006396)
0.0	0.2	GO:0035272	exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0	0.1	GO:0006284	base-excision repair(GO:0006284)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	16.9	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
4.9	34.6	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
4.4	17.6	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
3.5	10.6	GO:0098536	deuterosome(GO:0098536)
3.5	13.9	GO:0005787	signal peptidase complex(GO:0005787)
2.8	11.1	GO:0005688	U6 snRNP(GO:0005688)
2.7	13.7	GO:0043625	delta DNA polymerase complex(GO:0043625)
2.6	28.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
2.5	12.4	GO:0031415	NatA complex(GO:0031415)
2.3	9.0	GO:0033186	CAF-1 complex(GO:0033186)
2.2	13.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
2.0	10.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
2.0	18.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
1.9	9.5	GO:0000444	MIS12/MIND type complex(GO:0000444)
1.8	42.5	GO:0005685	U1 snRNP(GO:0005685)
1.8	9.1	GO:0031501	mannosyltransferase complex(GO:0031501)
1.7	43.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.5	6.2	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.5	10.7	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
1.5	16.8	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
1.5	16.6	GO:0072546	ER membrane protein complex(GO:0072546)
1.5	9.0	GO:0031262	Ndc80 complex(GO:0031262)
1.5	10.4	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.4	4.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.3	14.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
1.3	9.1	GO:0005663	DNA replication factor C complex(GO:0005663)
1.3	7.6	GO:0070449	elongin complex(GO:0070449)
1.3	17.7	GO:0005686	U2 snRNP(GO:0005686)
1.2	19.4	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.2	15.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.1	33.8	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
1.1	15.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
1.1	3.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.0	9.3	GO:0035145	exon-exon junction complex(GO:0035145)
1.0	11.1	GO:0030126	COPI vesicle coat(GO:0030126)
1.0	10.6	GO:0005689	U12-type spliceosomal complex(GO:0005689)
1.0	6.7	GO:0070847	core mediator complex(GO:0070847)
1.0	19.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.9	5.5	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.9	6.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.9	2.7	GO:0034708	methyltransferase complex(GO:0034708)
0.9	15.8	GO:0042555	MCM complex(GO:0042555)
0.9	14.0	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.9	8.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.9	20.5	GO:0032040	small-subunit processome(GO:0032040)
0.9	4.3	GO:0031298	replication fork protection complex(GO:0031298)
0.8	7.4	GO:0016272	prefoldin complex(GO:0016272)
0.8	11.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.8	4.7	GO:0030891	VCB complex(GO:0030891)
0.8	17.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.8	12.5	GO:0036038	MKS complex(GO:0036038)
0.8	10.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.7	8.0	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.7	4.3	GO:0042788	polysomal ribosome(GO:0042788)
0.7	15.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.7	2.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.7	6.8	GO:0005675	holo TFIIH complex(GO:0005675)
0.7	2.7	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.7	2.0	GO:0031251	PAN complex(GO:0031251)
0.7	5.3	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.6	7.8	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6	14.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.6	3.1	GO:0005673	transcription factor TFIIE complex(GO:0005673)
0.6	1.8	GO:0043614	multi-eIF complex(GO:0043614)
0.6	4.7	GO:0033061	DNA recombinase mediator complex(GO:0033061)
0.6	1.8	GO:0097361	CIA complex(GO:0097361)
0.6	4.7	GO:0070552	BRISC complex(GO:0070552)
0.6	11.6	GO:0005684	U2-type spliceosomal complex(GO:0005684)
0.6	2.9	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.6	2.3	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.6	10.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.6	4.0	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6	3.4	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.6	3.9	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.6	6.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.5	7.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.5	4.4	GO:0070765	gamma-secretase complex(GO:0070765)
0.5	4.9	GO:0000124	SAGA complex(GO:0000124)
0.5	3.7	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.5	2.6	GO:0070390	transcription export complex 2(GO:0070390)
0.5	2.6	GO:0005662	DNA replication factor A complex(GO:0005662)
0.5	1.5	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.5	3.5	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.5	4.4	GO:0032021	NELF complex(GO:0032021)
0.5	8.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.5	5.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.5	0.5	GO:0034456	CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.5	1.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.5	36.3	GO:0000776	kinetochore(GO:0000776)
0.5	11.9	GO:0005876	spindle microtubule(GO:0005876)
0.4	3.1	GO:1990130	Iml1 complex(GO:1990130)
0.4	18.8	GO:0005861	troponin complex(GO:0005861)
0.4	4.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.4	1.2	GO:0042382	paraspeckles(GO:0042382)
0.4	0.4	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.4	28.4	GO:0031228	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.4	2.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4	2.0	GO:0018444	translation release factor complex(GO:0018444)
0.4	3.9	GO:0032300	mismatch repair complex(GO:0032300)
0.4	16.9	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4	3.0	GO:0001772	immunological synapse(GO:0001772)
0.4	18.1	GO:0005643	nuclear pore(GO:0005643)
0.4	11.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4	7.9	GO:0032039	integrator complex(GO:0032039)
0.4	1.5	GO:0032133	chromosome passenger complex(GO:0032133)
0.4	37.7	GO:0016607	nuclear speck(GO:0016607)
0.4	11.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.3	7.8	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.3	2.0	GO:0071986	Ragulator complex(GO:0071986)
0.3	1.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3	5.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.3	25.8	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.3	3.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3	1.9	GO:0070876	SOSS complex(GO:0070876)
0.3	1.2	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.3	5.2	GO:0005838	proteasome regulatory particle(GO:0005838)
0.3	1.5	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.3	2.1	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3	18.5	GO:0005681	spliceosomal complex(GO:0005681)
0.3	5.8	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.3	2.0	GO:0005667	transcription factor complex(GO:0005667)
0.3	4.6	GO:0005801	cis-Golgi network(GO:0005801)
0.3	0.3	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.3	7.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.3	3.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	1.7	GO:0030686	90S preribosome(GO:0030686)
0.3	1.4	GO:0033263	CORVET complex(GO:0033263)
0.3	0.8	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.3	1.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.3	3.5	GO:0017119	Golgi transport complex(GO:0017119)
0.3	1.9	GO:0071818	BAT3 complex(GO:0071818)
0.3	58.8	GO:0005730	nucleolus(GO:0005730)
0.3	14.0	GO:0016604	nuclear body(GO:0016604)
0.3	13.5	GO:0005811	lipid particle(GO:0005811)
0.3	0.8	GO:0090443	FAR/SIN/STRIPAK complex(GO:0090443)
0.3	2.0	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.2	3.6	GO:0071564	npBAF complex(GO:0071564)
0.2	3.6	GO:0033290	eukaryotic 48S preinitiation complex(GO:0033290)
0.2	1.1	GO:0000814	ESCRT II complex(GO:0000814)
0.2	2.3	GO:0008180	COP9 signalosome(GO:0008180)
0.2	3.9	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2	2.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.2	3.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	3.3	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.2	1.5	GO:0097346	INO80-type complex(GO:0097346)
0.2	0.4	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2	5.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	0.7	GO:0070695	FHF complex(GO:0070695)
0.2	0.7	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.2	2.2	GO:0031010	ISWI-type complex(GO:0031010)
0.2	1.4	GO:0030990	intraciliary transport particle(GO:0030990)
0.2	4.9	GO:0000145	exocyst(GO:0000145)
0.2	30.8	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.2	1.4	GO:0016586	RSC complex(GO:0016586)
0.2	14.2	GO:0005795	Golgi stack(GO:0005795)
0.2	0.8	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.2	5.5	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2	0.8	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2	0.3	GO:1990072	TRAPPIII protein complex(GO:1990072)
0.1	1.6	GO:0098827	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1	0.7	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.1	4.0	GO:0032156	septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1	3.1	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	41.1	GO:0000139	Golgi membrane(GO:0000139)
0.1	1.0	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.7	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	1.4	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	2.3	GO:0000813	ESCRT I complex(GO:0000813)
0.1	2.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	9.4	GO:0005871	kinesin complex(GO:0005871)
0.1	0.7	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	1.1	GO:0071797	LUBAC complex(GO:0071797)
0.1	8.6	GO:0005814	centriole(GO:0005814)
0.1	10.8	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	1.6	GO:0005869	dynactin complex(GO:0005869)
0.1	1.0	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	17.4	GO:0005813	centrosome(GO:0005813)
0.1	4.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	4.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	0.5	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1	2.0	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	3.4	GO:0000781	chromosome, telomeric region(GO:0000781)
0.1	4.1	GO:0098978	glutamatergic synapse(GO:0098978)
0.1	1.6	GO:0000775	chromosome, centromeric region(GO:0000775)
0.1	10.3	GO:0005925	focal adhesion(GO:0005925)
0.1	1.5	GO:0005839	proteasome core complex(GO:0005839)
0.1	5.9	GO:0005802	trans-Golgi network(GO:0005802)
0.1	11.1	GO:0005769	early endosome(GO:0005769)
0.1	6.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.7	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.2	GO:0055087	Ski complex(GO:0055087)
0.1	9.2	GO:0016324	apical plasma membrane(GO:0016324)
0.1	1.0	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.7	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	1.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	4.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	2.5	GO:0005902	microvillus(GO:0005902)
0.1	342.2	GO:0005634	nucleus(GO:0005634)
0.1	0.4	GO:0036156	inner dynein arm(GO:0036156)
0.0	1.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	1.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	3.4	GO:0005604	basement membrane(GO:0005604)
0.0	0.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	3.7	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.6	GO:0030175	filopodium(GO:0030175)
0.0	0.7	GO:0036064	ciliary basal body(GO:0036064)
0.0	1.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.2	GO:0001401	mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0	1.4	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	2.8	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	1.8	GO:0045111	intermediate filament(GO:0005882) intermediate filament cytoskeleton(GO:0045111)
0.0	1.2	GO:0030141	secretory granule(GO:0030141)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.5	31.5	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
5.9	17.6	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
4.8	14.5	GO:0071532	ankyrin repeat binding(GO:0071532)
4.6	13.8	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
4.1	32.4	GO:0030619	U1 snRNA binding(GO:0030619)
3.1	12.5	GO:0070182	DNA polymerase binding(GO:0070182)
2.9	11.4	GO:0034511	U3 snoRNA binding(GO:0034511)
2.6	10.6	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
2.5	9.9	GO:0002151	G-quadruplex RNA binding(GO:0002151)
2.3	27.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
2.2	11.2	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
2.2	6.6	GO:0015086	cadmium ion transmembrane transporter activity(GO:0015086)
2.2	6.5	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
1.9	21.3	GO:0031013	troponin C binding(GO:0030172) troponin I binding(GO:0031013)
1.9	5.8	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
1.9	11.4	GO:0061133	endopeptidase activator activity(GO:0061133)
1.7	6.7	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
1.7	13.2	GO:0001130	bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
1.5	16.0	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
1.4	7.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.4	12.4	GO:0032977	membrane insertase activity(GO:0032977)
1.4	15.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
1.3	5.3	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
1.3	2.5	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2	3.7	GO:0080122	coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.2	2.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.1	8.9	GO:0034452	dynactin binding(GO:0034452)
1.1	8.8	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
1.1	10.6	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0	9.4	GO:0008494	translation activator activity(GO:0008494)
1.0	3.1	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
1.0	15.5	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
1.0	12.9	GO:0030515	snoRNA binding(GO:0030515)
1.0	17.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
1.0	8.7	GO:0009378	four-way junction helicase activity(GO:0009378)
1.0	3.8	GO:0051059	NF-kappaB binding(GO:0051059)
1.0	4.8	GO:1990756	protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
1.0	3.8	GO:0003979	UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.9	7.6	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.9	4.7	GO:0060182	apelin receptor activity(GO:0060182)
0.9	2.8	GO:0046403	polynucleotide 3'-phosphatase activity(GO:0046403)
0.9	2.7	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.9	6.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.9	8.7	GO:0008172	S-methyltransferase activity(GO:0008172)
0.9	5.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.9	7.7	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.9	19.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.8	8.5	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.8	5.9	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.8	21.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.8	4.1	GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.8	12.2	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.8	4.0	GO:0004408	holocytochrome-c synthase activity(GO:0004408)
0.8	10.3	GO:0043028	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.8	4.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.8	4.6	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.8	2.3	GO:0045545	syndecan binding(GO:0045545)
0.7	3.7	GO:0008106	alditol:NADP+ 1-oxidoreductase activity(GO:0004032) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.7	3.7	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.7	3.0	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.7	37.1	GO:0043022	ribosome binding(GO:0043022)
0.7	14.4	GO:0097602	cullin family protein binding(GO:0097602)
0.7	15.0	GO:0045182	translation regulator activity(GO:0045182)
0.7	5.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.7	12.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.7	3.5	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.7	5.5	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.7	2.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.7	8.8	GO:0005537	mannose binding(GO:0005537)
0.7	18.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.7	8.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.7	3.3	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.7	3.3	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.6	1.9	GO:0070735	protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.6	4.4	GO:0019809	spermidine binding(GO:0019809)
0.6	3.0	GO:0019863	IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.6	1.8	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6	10.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6	3.5	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.6	1.8	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.6	2.3	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.6	15.4	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.6	1.7	GO:0051185	coenzyme transporter activity(GO:0051185)
0.6	1.7	GO:0003978	UDP-glucose 4-epimerase activity(GO:0003978)
0.6	5.0	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.5	9.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.5	3.7	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.5	2.6	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.5	12.9	GO:0005112	Notch binding(GO:0005112)
0.5	1.0	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.5	6.0	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.5	2.0	GO:0033204	ribonuclease P RNA binding(GO:0033204)
0.5	0.9	GO:0004738	pyruvate dehydrogenase activity(GO:0004738)
0.5	3.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.4	1.3	GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.4	5.6	GO:0061665	SUMO ligase activity(GO:0061665)
0.4	3.8	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.4	5.9	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4	34.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.4	5.3	GO:0016783	sulfurtransferase activity(GO:0016783)
0.4	2.4	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.4	1.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.4	2.8	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.4	7.0	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.4	14.9	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.4	3.7	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.4	3.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.4	1.4	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.3	11.4	GO:0030145	manganese ion binding(GO:0030145)
0.3	2.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3	5.7	GO:0004532	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.3	1.3	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3	3.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	2.3	GO:0070698	type I activin receptor binding(GO:0070698)
0.3	1.3	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.3	2.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3	4.9	GO:0051879	Hsp90 protein binding(GO:0051879)
0.3	2.6	GO:0003993	acid phosphatase activity(GO:0003993)
0.3	7.8	GO:0031072	heat shock protein binding(GO:0031072)
0.3	1.6	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.3	1.3	GO:0044548	S100 protein binding(GO:0044548)
0.3	16.1	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3	2.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.3	14.6	GO:0019843	rRNA binding(GO:0019843)
0.3	2.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.3	17.0	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3	2.3	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3	4.6	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.3	5.8	GO:0070411	I-SMAD binding(GO:0070411)
0.3	21.6	GO:0003724	RNA helicase activity(GO:0003724)
0.3	1.2	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.3	1.7	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.3	7.3	GO:0000339	RNA cap binding(GO:0000339)
0.3	1.1	GO:0030331	estrogen receptor binding(GO:0030331)
0.3	1.1	GO:0000217	DNA secondary structure binding(GO:0000217)
0.3	0.8	GO:0017050	D-erythro-sphingosine kinase activity(GO:0017050)
0.3	1.1	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3	1.8	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.3	6.4	GO:0003684	damaged DNA binding(GO:0003684)
0.3	0.5	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	11.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.3	1.0	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2	4.2	GO:0004382	guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2	1.7	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2	1.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.2	1.7	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.2	12.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.2	0.7	GO:0016748	succinyltransferase activity(GO:0016748)
0.2	0.7	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.2	0.9	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	7.6	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.2	4.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.2	3.5	GO:0051117	ATPase binding(GO:0051117)
0.2	1.4	GO:0017070	U6 snRNA binding(GO:0017070)
0.2	0.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	3.9	GO:0030983	mismatched DNA binding(GO:0030983)
0.2	3.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	9.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.2	0.7	GO:0009041	uridylate kinase activity(GO:0009041)
0.2	16.7	GO:0043130	ubiquitin binding(GO:0043130)
0.2	0.6	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2	15.2	GO:0051082	unfolded protein binding(GO:0051082)
0.2	0.6	GO:0016623	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2	1.3	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2	1.5	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2	2.9	GO:0002020	protease binding(GO:0002020)
0.2	3.3	GO:0031386	protein tag(GO:0031386)
0.2	10.2	GO:0031491	nucleosome binding(GO:0031491)
0.2	6.3	GO:0000049	tRNA binding(GO:0000049)
0.2	4.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2	170.7	GO:0003723	RNA binding(GO:0003723)
0.2	12.8	GO:0042054	histone methyltransferase activity(GO:0042054)
0.2	1.5	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2	2.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.2	0.2	GO:0052813	phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	1.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2	1.5	GO:0015154	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2	0.9	GO:0008430	selenium binding(GO:0008430)
0.2	21.6	GO:0003777	microtubule motor activity(GO:0003777)
0.2	0.6	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2	5.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	0.9	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	5.1	GO:0016208	AMP binding(GO:0016208)
0.2	10.2	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	3.9	GO:0005003	ephrin receptor activity(GO:0005003)
0.2	4.9	GO:0031625	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.2	1.6	GO:0042162	telomeric DNA binding(GO:0042162)
0.2	0.5	GO:0047291	lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2	3.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	1.4	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.2	0.6	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2	0.8	GO:0015117	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.2	5.4	GO:0035064	methylated histone binding(GO:0035064)
0.2	2.7	GO:0008417	fucosyltransferase activity(GO:0008417)
0.2	2.7	GO:0031729	CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2	1.1	GO:0030274	LIM domain binding(GO:0030274)
0.2	2.0	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	2.1	GO:0061608	nuclear localization sequence binding(GO:0008139) nuclear import signal receptor activity(GO:0061608)
0.1	2.2	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1	1.7	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	1.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	2.0	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	2.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	2.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.8	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	1.8	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	46.7	GO:0003924	GTPase activity(GO:0003924)
0.1	1.2	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.1	3.7	GO:0008276	protein methyltransferase activity(GO:0008276)
0.1	0.5	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1	1.5	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	1.5	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	2.1	GO:0051018	protein kinase A binding(GO:0051018)
0.1	12.4	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	1.4	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.2	GO:0031781	type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 1 melanocortin receptor binding(GO:0070996)
0.1	1.0	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.1	6.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	1.3	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	14.4	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	1.7	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.1	39.5	GO:0003712	transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1	18.2	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	1.5	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1	1.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	4.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.3	GO:0004394	heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1	7.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	0.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1	0.5	GO:0004001	adenosine kinase activity(GO:0004001)
0.1	0.5	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.1	2.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	24.9	GO:0008270	zinc ion binding(GO:0008270)
0.1	1.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	8.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	5.1	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	1.5	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	1.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	1.5	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	1.3	GO:0032190	acrosin binding(GO:0032190)
0.1	1.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	21.9	GO:0016887	ATPase activity(GO:0016887)
0.1	1.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828)
0.1	1.6	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	1.6	GO:0015926	glucosidase activity(GO:0015926)
0.1	0.3	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	1.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.1	14.0	GO:0005525	GTP binding(GO:0005525)
0.1	0.7	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.6	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	0.8	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1	0.5	GO:0015923	mannosidase activity(GO:0015923)
0.1	0.1	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702) oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1	0.9	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.9	GO:0005504	fatty acid binding(GO:0005504)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	28.5	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.1	1.4	GO:0015248	sterol transporter activity(GO:0015248)
0.1	1.8	GO:0004386	helicase activity(GO:0004386)
0.1	1.0	GO:0004521	endoribonuclease activity(GO:0004521)
0.1	2.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.2	GO:0008117	sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0	0.4	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	22.2	GO:0046983	protein dimerization activity(GO:0046983)
0.0	0.7	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.5	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	1.5	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0019777	Atg12 transferase activity(GO:0019777)
0.0	1.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	1.0	GO:0019213	deacetylase activity(GO:0019213)
0.0	1.9	GO:0005178	integrin binding(GO:0005178)
0.0	0.4	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.3	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.0	1.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.5	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.3	GO:0036374	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0	0.2	GO:1902388	ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0	14.0	GO:0004175	endopeptidase activity(GO:0004175)
0.0	13.6	GO:0005198	structural molecule activity(GO:0005198)
0.0	7.5	GO:0016746	transferase activity, transferring acyl groups(GO:0016746)
0.0	90.6	GO:0003676	nucleic acid binding(GO:0003676)
0.0	0.3	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	0.4	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	3.7	GO:0005179	hormone activity(GO:0005179)
0.0	1.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	6.5	GO:0030246	carbohydrate binding(GO:0030246)
0.0	1.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.7	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.4	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.4	GO:0004698	protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0	10.8	GO:0003779	actin binding(GO:0003779)
0.0	0.6	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleoside transmembrane transporter activity(GO:0015211) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0098809	nitrite reductase activity(GO:0098809)
0.0	0.4	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.4	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	1.1	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	0.5	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.2	GO:0019870	chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	8.5	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.6	1.6	PID PI3KCI PATHWAY	Class I PI3K signaling events
1.1	15.8	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.9	9.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.9	1.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.8	30.3	PID AURORA B PATHWAY	Aurora B signaling
0.7	10.1	PID ALK2 PATHWAY	ALK2 signaling events
0.6	26.8	PID ATR PATHWAY	ATR signaling pathway
0.6	4.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.6	12.7	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.4	7.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.4	8.6	PID ATM PATHWAY	ATM pathway
0.4	20.3	PID NOTCH PATHWAY	Notch signaling pathway
0.4	5.7	PID AURORA A PATHWAY	Aurora A signaling
0.3	6.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.3	8.7	PID PLK1 PATHWAY	PLK1 signaling events
0.3	2.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	2.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	16.3	PID P73PATHWAY	p73 transcription factor network
0.3	16.7	PID E2F PATHWAY	E2F transcription factor network
0.3	0.9	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	10.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	7.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.2	1.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	9.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.2	15.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	7.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	2.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	3.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	2.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	1.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	2.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	4.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	2.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	0.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	3.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	2.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	1.9	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	4.6	PID CDC42 PATHWAY	CDC42 signaling events
0.1	0.7	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	1.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	0.7	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	1.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	13.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	0.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	2.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	3.5	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	0.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	2.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	2.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	0.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	2.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	0.9	PID MYC PATHWAY	C-MYC pathway
0.1	1.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.8	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.4	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	5.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	1.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	1.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.5	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	2.5	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
2.4	14.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
1.9	33.0	REACTOME POL SWITCHING	Genes involved in Polymerase switching
1.6	63.7	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
1.5	36.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.4	10.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.3	44.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
1.3	13.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.2	33.6	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
1.2	22.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.2	18.7	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
1.1	19.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.0	20.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.9	11.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.9	12.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.8	26.6	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.8	17.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8	12.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.8	4.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.7	19.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.7	5.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.7	6.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.7	19.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.7	13.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.6	13.6	REACTOME KINESINS	Genes involved in Kinesins
0.6	35.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.6	9.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.6	5.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.6	4.6	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.5	5.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.5	1.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.4	32.4	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.4	4.7	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.4	6.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.4	6.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.4	6.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4	3.0	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.3	2.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	13.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3	11.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.3	9.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3	4.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3	4.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	4.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3	5.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3	25.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	6.8	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.3	3.0	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	3.0	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	14.1	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.2	2.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2	2.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	11.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	2.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	1.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	1.6	REACTOME METABOLISM OF RNA	Genes involved in Metabolism of RNA
0.2	9.6	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2	3.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	3.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	2.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.2	2.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	2.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	3.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	2.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.7	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1	1.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.9	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	0.7	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	0.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	4.1	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.1	0.3	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	0.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.0	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.1	2.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	2.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	0.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.7	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	0.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	2.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.8	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Results for etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Z-value: 6.17

Motif logo

Transcription factors associated with etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Activity-expression correlation:

Activity profile of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Sorted Z-values of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: