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PRJEB1986: zebrafish developmental stages transcriptome

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Results for ets2

Z-value: 0.69

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Transcription factors associated with ets2

Gene Symbol Gene ID Gene Info
ENSDARG00000103980 v-ets avian erythroblastosis virus E26 oncogene homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ets2dr11_v1_chr10_+_187760_187764-0.214.0e-01Click!

Activity profile of ets2 motif

Sorted Z-values of ets2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_32335871 1.25 ENSDART00000149698
solute carrier family 39 (zinc transporter), member 5
chr11_+_8129536 1.21 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr12_-_48312647 1.10 ENSDART00000114415
activating signal cointegrator 1 complex subunit 1
chr25_+_5015019 1.05 ENSDART00000127600
histone deacetylase 10
chr17_-_24890843 1.02 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
UDP-galactose-4-epimerase
chr1_-_59571758 1.01 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr7_+_19374683 1.01 ENSDART00000162700
small nuclear ribonucleoprotein polypeptide F
chr3_+_19665319 0.98 ENSDART00000007857
ENSDART00000193509
methyltransferase like 2A
chr3_-_45777226 0.94 ENSDART00000192849
H3 histone, family 3B.1
chr14_-_41478265 0.89 ENSDART00000149886
ENSDART00000016002
tetraspanin 7
chr23_+_33957350 0.86 ENSDART00000172069
small nuclear ribonucleoprotein polypeptide G
chr7_-_66133786 0.83 ENSDART00000154961
BTB (POZ) domain containing 10b
chr10_+_9553935 0.82 ENSDART00000028855
si:ch211-243g18.2
chr13_+_33651416 0.80 ENSDART00000180221

chr11_-_36350876 0.77 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr2_+_13907452 0.77 ENSDART00000169724
ENSDART00000190691
zgc:66475
chr18_-_3552414 0.77 ENSDART00000163762
ENSDART00000165434
ENSDART00000161197
ENSDART00000166841
ENSDART00000170260
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr20_-_36800002 0.76 ENSDART00000015190
peptidyl-tRNA hydrolase domain containing 1
chr7_-_38687431 0.75 ENSDART00000074490
apelin receptor 2
chr19_+_1873059 0.75 ENSDART00000145246
small nuclear ribonucleoprotein D1 polypeptide
chr8_-_31107537 0.74 ENSDART00000098925
vestigial like 4 like
chr17_-_14836320 0.71 ENSDART00000157051
nidogen 2a (osteonidogen)
chr16_+_38201840 0.71 ENSDART00000044971
myosin IE, b
chr15_-_3277635 0.71 ENSDART00000189094
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr7_-_57637779 0.70 ENSDART00000028017
MAD2 mitotic arrest deficient-like 1 (yeast)
chr6_+_49255706 0.70 ENSDART00000156866
si:dkey-183k8.2
chr6_+_43400059 0.69 ENSDART00000143374
microphthalmia-associated transcription factor a
chr10_+_40324395 0.68 ENSDART00000147205
glycolipid transfer protein b
chr18_+_7543347 0.67 ENSDART00000103467
ADP-ribosylation factor 5
chr10_-_8046764 0.67 ENSDART00000099031
zgc:136254
chr2_-_22363460 0.67 ENSDART00000158486
selenoprotein F
chr10_-_8053385 0.67 ENSDART00000142714
si:ch211-251f6.7
chr5_-_7513082 0.66 ENSDART00000158913
bone morphogenetic protein receptor, type IBa
chr6_+_40775800 0.65 ENSDART00000085090
si:ch211-157b11.8
chr7_+_56453646 0.64 ENSDART00000112483
solute carrier family 22, member 31
chr8_+_19489854 0.64 ENSDART00000184671
ENSDART00000011258
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_-_17711636 0.64 ENSDART00000148322
ENSDART00000122670
ufm1-specific peptidase 2
chr2_-_20715094 0.64 ENSDART00000155439
dual specificity phosphatase 12
chr23_+_9560797 0.64 ENSDART00000180014
adhesion regulating molecule 1
chr21_+_30351256 0.63 ENSDART00000078341
forkhead box I3a
chr19_-_22843480 0.63 ENSDART00000052503
NudC domain containing 1
chr12_+_10443785 0.63 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr5_-_54712159 0.63 ENSDART00000149207
cyclin B1
chr17_+_10242166 0.63 ENSDART00000170420
C-type lectin domain containing 14A
chr12_-_49149800 0.62 ENSDART00000182290
BUB3 mitotic checkpoint protein
chr5_+_69733096 0.61 ENSDART00000169013
ADP-ribosylation factor-like 6 interacting protein 4
chr3_-_45281350 0.61 ENSDART00000020168
potassium channel tetramerization domain containing 5a
chr19_+_25649626 0.61 ENSDART00000146947
tachykinin 1
chr20_+_27087539 0.61 ENSDART00000062094
transmembrane protein 251
chr19_+_1872794 0.61 ENSDART00000013217
small nuclear ribonucleoprotein D1 polypeptide
chr6_+_27090800 0.60 ENSDART00000121558
autophagy related 4B, cysteine peptidase
chr8_-_50135492 0.60 ENSDART00000149398
si:ch73-132k15.2
chr17_-_10000339 0.60 ENSDART00000162893
sorting nexin 6
chr5_+_15495351 0.60 ENSDART00000111646
ENSDART00000114446
SDS3 homolog, SIN3A corepressor complex component
chr20_-_14462995 0.60 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr12_-_4301234 0.59 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr16_-_41805240 0.59 ENSDART00000034078
proteasome 26S subunit, ATPase 4
chr3_+_23691847 0.59 ENSDART00000078453
homeobox B7a
chr4_+_2637947 0.59 ENSDART00000130623
dihydrouridine synthase 4-like (S. cerevisiae)
chr13_-_49802194 0.59 ENSDART00000148722
beta-1,3-N-acetylgalactosaminyltransferase 2
chr13_+_46177478 0.58 ENSDART00000056987
MARCKS-like 1a
chr9_+_54179306 0.57 ENSDART00000189829
thymosin, beta 4 x
chr20_+_51813432 0.57 ENSDART00000127444
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr7_-_24621689 0.56 ENSDART00000101265
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr10_-_8053753 0.56 ENSDART00000162289
si:ch211-251f6.7
chr9_-_7673856 0.55 ENSDART00000102715
tubulin, alpha 8 like 3
chr6_-_33924883 0.55 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr10_+_8875195 0.55 ENSDART00000141045
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr25_+_3549401 0.54 ENSDART00000166312
coiled-coil domain containing 77
chr19_+_47476908 0.54 ENSDART00000157886
zgc:114119
chr21_-_22117085 0.54 ENSDART00000146673
solute carrier family 35, member F2
chr11_+_19502297 0.54 ENSDART00000103987
proteasome 26S subunit, non-ATPase 6
chr7_-_69025306 0.54 ENSDART00000180796

chr16_-_48430272 0.53 ENSDART00000005927
RAD21 cohesin complex component a
chr19_+_20793388 0.53 ENSDART00000142463
thioredoxin-like 4A
chr20_+_54304800 0.53 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr1_+_38142354 0.53 ENSDART00000179352
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr14_-_16807206 0.53 ENSDART00000157957
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr13_-_25767210 0.52 ENSDART00000131792
PDZ and LIM domain 1 (elfin)
chr19_-_25693728 0.52 ENSDART00000136187
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr6_-_49215790 0.52 ENSDART00000103376
ENSDART00000132347
ENSDART00000132131
ENSDART00000143252
ENSDART00000065033
nerve growth factor b (beta polypeptide)
chr19_+_20793237 0.52 ENSDART00000014774
thioredoxin-like 4A
chr7_-_24994568 0.51 ENSDART00000002961
REST corepressor 2
chr2_-_21167652 0.51 ENSDART00000185792
bmi1 polycomb ring finger oncogene 1b
chr15_+_30310843 0.51 ENSDART00000112784
LYR motif containing 9
chr12_-_28363111 0.51 ENSDART00000016283
ENSDART00000164156
proteasome 26S subunit, non-ATPase 11b
chr23_-_45318760 0.51 ENSDART00000166883
coiled-coil domain containing 171
chr18_+_40381102 0.50 ENSDART00000136588
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr7_+_26716321 0.50 ENSDART00000189750
CD82 molecule a
chr19_+_7292654 0.50 ENSDART00000140459
coiled-coil domain containing 127b
chr19_-_43757568 0.50 ENSDART00000058491
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr14_+_14043793 0.50 ENSDART00000164376
Ras-related GTP binding A
chr22_-_193234 0.50 ENSDART00000131067
F-box protein 42
chr25_-_25575717 0.50 ENSDART00000067138
hypermethylated in cancer 1 like
chr13_-_5064481 0.49 ENSDART00000091806
ENSDART00000032322
ATP-binding cassette, sub-family G (WHITE), member 2c
chr12_+_28955766 0.49 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr19_-_33274978 0.48 ENSDART00000020301
ENSDART00000114714
family with sequence similarity 92, member A1
chr3_-_6608342 0.48 ENSDART00000161188
si:ch73-59f11.3
chr20_+_54299419 0.48 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr2_-_32512648 0.48 ENSDART00000170674
ATP-binding cassette, sub-family F (GCN20), member 2a
chr5_+_10084100 0.48 ENSDART00000109236
si:ch211-207k7.4
chr6_-_33925381 0.48 ENSDART00000137268
ENSDART00000145019
ENSDART00000141822
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr21_-_26715270 0.48 ENSDART00000053794
barrier to autointegration factor 1
chr21_+_28747069 0.47 ENSDART00000014058
zgc:100829
chr24_+_18714212 0.47 ENSDART00000171181
centrosome and spindle pole associated protein 1a
chr3_-_54544612 0.47 ENSDART00000018044
angiopoietin-like 6
chr4_-_59417501 0.47 ENSDART00000163357

chr20_+_35282682 0.47 ENSDART00000187199
family with sequence similarity 49, member A
chr9_+_21148318 0.47 ENSDART00000035428
hydroxyacid oxidase 2 (long chain)
chr13_+_5978809 0.47 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr3_-_37785873 0.47 ENSDART00000011691
BCL2 associated X, apoptosis regulator a
chr18_+_3140682 0.46 ENSDART00000166382
chloride channel, nucleotide-sensitive, 1A
chr1_+_38818268 0.46 ENSDART00000166864
signal peptidase complex subunit 3
chr10_+_2684958 0.46 ENSDART00000112019
SET domain containing 9
chr1_-_44581937 0.46 ENSDART00000009858
thioredoxin-related transmembrane protein 2b
chr4_-_330748 0.46 ENSDART00000067488
mitochondrial ribosomal protein S10
chr3_+_59880317 0.46 ENSDART00000166922
ENSDART00000108647
Aly/REF export factor
chr23_-_20133994 0.46 ENSDART00000004871
leucine rich repeat containing 23
chr11_+_44548209 0.45 ENSDART00000181798
ENSDART00000191742
ENSDART00000168209
nidogen 1b
chr7_-_18470963 0.45 ENSDART00000173929
ENSDART00000173638
zinc finger protein 16 like
chr12_+_19199735 0.45 ENSDART00000066393
pdgfa associated protein 1a
chr20_+_54309148 0.45 ENSDART00000099360
zona pellucida glycoprotein 2, tandem duplicate 1
chr12_-_49168398 0.45 ENSDART00000186608

chr25_+_3549841 0.45 ENSDART00000164030
coiled-coil domain containing 77
chr20_+_54295213 0.45 ENSDART00000074085
zona pellucida glycoprotein 2, tandem duplicate 3
chr7_+_41340520 0.45 ENSDART00000005127
GRB2 associated, regulator of MAPK1
chr20_+_28803642 0.45 ENSDART00000188526
farnesyltransferase, CAAX box, beta
chr10_-_26997344 0.45 ENSDART00000146595
zgc:193742
chr15_-_5799170 0.44 ENSDART00000142334
ENSDART00000171528
heterogeneous nuclear ribonucleoprotein L2
chr13_+_15933168 0.44 ENSDART00000131390
fidgetin-like 1
chr22_-_20403194 0.44 ENSDART00000010048
mitogen-activated protein kinase kinase 2a
chr20_+_54290356 0.44 ENSDART00000173347
zona pellucida glycoprotein 2, tandem duplicate 2
chr19_-_24757231 0.44 ENSDART00000128177
si:dkey-154b15.1
chr4_+_18441988 0.43 ENSDART00000040827
non-SMC condensin II complex, subunit H2
chr18_-_16907436 0.43 ENSDART00000146464
switching B cell complex subunit SWAP70b
chr5_+_4366431 0.43 ENSDART00000168560
ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr2_-_37281748 0.43 ENSDART00000137598
NAD kinase b
chr25_-_6223567 0.43 ENSDART00000067512
proteasome subunit alpha 4
chr13_+_29519115 0.43 ENSDART00000086711
carbohydrate (chondroitin 6) sulfotransferase 3a
chr20_+_25581627 0.43 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9
chr22_-_14115292 0.43 ENSDART00000105717
ENSDART00000165670
aldehyde oxidase 5
chr6_+_40554551 0.42 ENSDART00000017859
ENSDART00000155928
DNA-damage inducible protein 2
chr3_+_23742868 0.42 ENSDART00000153512
homeobox B3a
chr12_+_22576404 0.42 ENSDART00000172053
capping protein (actin filament), gelsolin-like b
chr13_-_35459928 0.42 ENSDART00000144109
SLX4 interacting protein
chr9_+_48819280 0.42 ENSDART00000112555
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_+_45395846 0.42 ENSDART00000058793
neudesin neurotrophic factor
chr23_+_9560991 0.42 ENSDART00000081433
ENSDART00000131594
ENSDART00000130069
ENSDART00000138601
adhesion regulating molecule 1
chr20_-_24183333 0.42 ENSDART00000025862
ENSDART00000153075
mitogen-activated protein kinase kinase kinase 7
chr9_+_56232548 0.42 ENSDART00000099276
CCR4-NOT transcription complex, subunit 11
chr20_+_39457598 0.42 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr24_+_14595680 0.42 ENSDART00000137337
ENSDART00000091784
ENSDART00000136026
thiamine triphosphatase
chr8_-_25033681 0.41 ENSDART00000003493
nuclear transcription factor Y, alpha, like
chr3_-_34136778 0.41 ENSDART00000131951
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr21_+_17024002 0.41 ENSDART00000080628
actin related protein 2/3 complex, subunit 3
chr7_+_34237189 0.41 ENSDART00000179624
timeless interacting protein
chr23_-_29751730 0.41 ENSDART00000056865
catenin, beta interacting protein 1
chr3_-_21061931 0.41 ENSDART00000036741
family with sequence similarity 57, member Ba
chr8_-_52715911 0.41 ENSDART00000168241
tubulin, beta 2b
chr20_+_54312970 0.41 ENSDART00000024598
ENSDART00000193172
zona pellucida glycoprotein 2, tandem duplicate 5
chr6_+_21684296 0.41 ENSDART00000057223
Ras homolog, mTORC1 binding like 1
chr4_+_5642696 0.41 ENSDART00000028941
mitochondrial ribosomal protein S18A
chr21_-_9383974 0.40 ENSDART00000160932
SDA1 domain containing 1
chr11_+_18157260 0.40 ENSDART00000144659
zgc:173545
chr19_-_18135724 0.40 ENSDART00000186609
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr16_+_42018041 0.40 ENSDART00000134010
ENSDART00000102789
Fli-1 proto-oncogene, ETS transcription factor b
chr19_+_3206263 0.40 ENSDART00000020344
zgc:86598
chr18_-_40884087 0.39 ENSDART00000059194
small nuclear ribonucleoprotein D2 polypeptide
chr14_+_38878482 0.39 ENSDART00000043317
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr20_+_39373480 0.39 ENSDART00000136714
Pim proto-oncogene, serine/threonine kinase, related 131
chr16_+_35401543 0.39 ENSDART00000171608
RAB42, member RAS oncogene family
chr23_+_35714574 0.39 ENSDART00000164616
tubulin, alpha 1c
chr14_+_6535426 0.39 ENSDART00000055961
tRNA-histidine guanylyltransferase 1-like
chr2_+_15048410 0.39 ENSDART00000058484
calponin 3, acidic b
chr11_-_287670 0.39 ENSDART00000035737
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr17_+_132555 0.39 ENSDART00000158159
zgc:77287
chr2_+_50094873 0.39 ENSDART00000132307
zinc finger, CCHC domain containing 2
chr10_+_8091144 0.39 ENSDART00000143848
ENSDART00000075485
SUB1 homolog, transcriptional regulator a
chr16_+_51154918 0.39 ENSDART00000058290
dehydrodolichyl diphosphate synthase
chr23_-_24699400 0.39 ENSDART00000104031
stromal cell derived factor 4
chr23_-_24146591 0.39 ENSDART00000133269
Rho guanine nucleotide exchange factor (GEF) 19
chr22_-_38801510 0.38 ENSDART00000140764
si:ch211-262h13.3
chr24_-_37472727 0.38 ENSDART00000134152
clusterin associated protein 1
chr15_-_35100858 0.38 ENSDART00000099677
biogenesis of lysosomal organelles complex-1, subunit 3
chr1_+_22691256 0.38 ENSDART00000017413
zinc finger, MYND-type containing 10
chr20_-_2619316 0.38 ENSDART00000185777
BUB1 mitotic checkpoint serine/threonine kinase
chr11_+_18130300 0.38 ENSDART00000169146
zgc:175135
chr14_+_23709543 0.38 ENSDART00000136909
glucosamine-6-phosphate deaminase 1
chr10_+_7671260 0.38 ENSDART00000157608
family with sequence similarity 136, member A
chr8_-_17997845 0.38 ENSDART00000121660
acyl-CoA thioesterase 11b
chr11_+_6882049 0.38 ENSDART00000075998
kelch-like family member 26
chr8_-_25814263 0.38 ENSDART00000143397
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_+_7424347 0.38 ENSDART00000004622
splicing factor 3b, subunit 4
chr4_+_7677318 0.38 ENSDART00000149218
ELK3, ETS-domain protein
chr16_+_46205693 0.38 ENSDART00000058385
ENSDART00000168145
bolA family member 1
chr13_+_12045758 0.37 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_36777613 0.37 ENSDART00000065644
ENSDART00000158151
parapinopsin b
chr11_+_24313931 0.37 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr4_+_7698862 0.37 ENSDART00000009909
ELK3, ETS-domain protein
chr1_-_157563 0.37 ENSDART00000018741
PCI domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ets2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.2 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.2 0.4 GO:0071514 genetic imprinting(GO:0071514)
0.2 1.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.0 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.6 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.2 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 4.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.9 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.7 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 1.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.3 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.3 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.6 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.7 GO:0035627 ceramide transport(GO:0035627)
0.1 0.4 GO:0010039 response to iron ion(GO:0010039)
0.1 0.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.5 GO:0043111 replication fork arrest(GO:0043111)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.4 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 1.3 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.6 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.5 GO:0032475 otolith formation(GO:0032475)
0.1 0.3 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.2 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.2 GO:0046324 regulation of glucose import(GO:0046324)
0.1 1.2 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 1.1 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.1 0.5 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.3 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0014014 negative regulation of gliogenesis(GO:0014014) positive regulation of DNA binding(GO:0043388) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.4 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.5 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0015740 C4-dicarboxylate transport(GO:0015740) acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.4 GO:0098926 postsynaptic signal transduction(GO:0098926)
0.0 1.2 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.0 0.4 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.7 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.4 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.6 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.1 GO:1901799 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.1 GO:0043300 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation involved in immune response(GO:0033006) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.6 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.3 GO:0060324 face development(GO:0060324)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 1.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0035476 angioblast cell migration(GO:0035476)
0.0 0.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:0034709 methylosome(GO:0034709) pICln-Sm protein complex(GO:0034715)
0.3 2.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.2 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.3 GO:0030891 VCB complex(GO:0030891)
0.1 0.6 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 1.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.3 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.5 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.5 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.1 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.5 GO:0070449 elongin complex(GO:0070449)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0030990 intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.3 1.1 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.3 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 1.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.6 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.7 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.2 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.8 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.7 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.9 GO:0051117 ATPase binding(GO:0051117)
0.1 0.4 GO:0019809 spermidine binding(GO:0019809)
0.1 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 1.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 3.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 2.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis