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PRJEB1986: zebrafish developmental stages transcriptome

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Results for esr1+esr2a+esr2b

Z-value: 1.76

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Transcription factors associated with esr1+esr2a+esr2b

Gene Symbol Gene ID Gene Info
ENSDARG00000004111 estrogen receptor 1
ENSDARG00000016454 estrogen receptor 2a
ENSDARG00000034181 estrogen receptor 2b
ENSDARG00000112357 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
esr1dr11_v1_chr20_-_26382284_263822840.606.6e-03Click!
esr2bdr11_v1_chr13_+_37022601_370226320.522.4e-02Click!
esr2adr11_v1_chr20_+_21583639_215836390.312.0e-01Click!

Activity profile of esr1+esr2a+esr2b motif

Sorted Z-values of esr1+esr2a+esr2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_44027391 13.44 ENSDART00000145404
crystallin, beta B1
chr9_-_22310919 8.29 ENSDART00000108719
crystallin, gamma M2d10
chr15_+_19797918 7.13 ENSDART00000113314
si:ch211-229d2.5
chr9_-_22240052 6.85 ENSDART00000111109
crystallin, gamma M2d9
chr9_-_22147567 6.68 ENSDART00000110941
crystallin, gamma M2d14
chr9_-_22272181 6.36 ENSDART00000113174
crystallin, gamma M2d7
chr9_-_22188117 6.34 ENSDART00000132890
crystallin, gamma M2d17
chr12_-_4683325 6.24 ENSDART00000152771
si:ch211-255p10.3
chr9_-_22318511 6.21 ENSDART00000129295
crystallin, gamma M2d2
chr1_+_17676745 6.09 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr6_-_13783604 5.80 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr16_+_12022543 5.75 ENSDART00000012673
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr9_-_22232902 5.64 ENSDART00000101845
crystallin, gamma M2d5
chr14_+_17376940 5.61 ENSDART00000054590
ENSDART00000010148
spondin 2b, extracellular matrix protein
chr12_-_30846055 5.33 ENSDART00000075983
crystallin, gamma MX, like 2
chr9_-_22352280 4.53 ENSDART00000115384
ENSDART00000060361
crystallin, gamma M5
chr20_+_5564042 4.51 ENSDART00000090934
ENSDART00000127050
neurexin 3b
chr6_+_48618512 4.28 ENSDART00000111190
si:dkey-238f9.1
chr23_-_26535875 4.16 ENSDART00000135988
si:dkey-205h13.2
chr1_-_59176949 4.05 ENSDART00000128742

chr23_-_45504991 3.96 ENSDART00000148761
collagen type XXIV alpha 1
chr5_-_71722257 3.86 ENSDART00000013404
adenylate kinase 1
chr24_-_38374744 3.83 ENSDART00000007208
leucine rich repeat containing 4Bb
chr23_-_39636195 3.78 ENSDART00000144439
von Willebrand factor A domain containing 1
chr3_-_41795917 3.74 ENSDART00000182662
galectin-related inter-fiber protein
chr11_+_30729745 3.64 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr16_-_560574 3.55 ENSDART00000148452
iroquois homeobox 2a
chr6_-_607063 3.40 ENSDART00000189900
lectin, galactoside-binding, soluble, 2b
chr4_-_16853464 3.36 ENSDART00000125743
ENSDART00000164570
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr4_+_17280868 3.34 ENSDART00000145349
branched chain amino-acid transaminase 1, cytosolic
chr17_-_6738538 3.33 ENSDART00000157125
visinin-like 1b
chr6_-_40722200 3.23 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr5_+_2815021 3.22 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr15_+_47386939 3.22 ENSDART00000128224

chr16_+_5774977 3.19 ENSDART00000134202
cholecystokinin a
chr4_-_16333944 3.16 ENSDART00000079523
epiphycan
chr17_-_12385308 3.11 ENSDART00000080927
synaptosomal-associated protein, 25b
chr19_-_5135345 3.06 ENSDART00000151787
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr5_-_41831646 3.01 ENSDART00000134326
si:dkey-65b12.6
chr3_+_32142382 2.99 ENSDART00000133035
synaptotagmin Va
chr6_-_49873020 2.98 ENSDART00000148511
GNAS complex locus
chr11_+_25477643 2.95 ENSDART00000065941
opsin 1 (cone pigments), long-wave-sensitive, 1
chr3_-_13147310 2.89 ENSDART00000160840
protein kinase, cAMP-dependent, regulatory, type I, beta
chr5_+_1278092 2.88 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr8_+_48613040 2.84 ENSDART00000121432
natriuretic peptide A
chr2_-_22688651 2.84 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr1_+_29096881 2.84 ENSDART00000075539
crystallin, alpha A
chr15_+_28096152 2.83 ENSDART00000100293
ENSDART00000140092
crystallin, beta B1, like 3
chr3_+_23488652 2.78 ENSDART00000126282
nuclear receptor subfamily 1, group d, member 1
chr2_-_38000276 2.72 ENSDART00000034790
Purkinje cell protein 4 like 1
chr9_-_23944470 2.68 ENSDART00000138754
collagen, type VI, alpha 3
chr5_-_29643381 2.68 ENSDART00000034849
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr20_+_30490682 2.68 ENSDART00000184871
myelin transcription factor 1-like, a
chr6_-_609880 2.68 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr21_-_131236 2.67 ENSDART00000160005
si:ch1073-398f15.1
chr6_+_10450000 2.67 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
potassium channel, voltage gated eag related subfamily H, member 7
chr23_-_26536055 2.66 ENSDART00000182719
si:dkey-205h13.2
chr20_-_34090740 2.64 ENSDART00000062539
ENSDART00000008140
phosducin b
chr8_-_49431939 2.63 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
synaptophysin b
chr8_+_22478090 2.62 ENSDART00000170263
si:ch211-261n11.7
chr23_+_44741500 2.58 ENSDART00000166421
ATPase Na+/K+ transporting subunit beta 2a
chr1_-_55810730 2.56 ENSDART00000100551
zgc:136908
chr10_+_37145007 2.54 ENSDART00000131777
CUE domain containing 1a
chr4_-_1360495 2.53 ENSDART00000164623
pleiotrophin
chr10_-_29900546 2.52 ENSDART00000147441
lens intrinsic membrane protein 2.1
chr18_-_16123222 2.49 ENSDART00000061189
sarcospan (Kras oncogene-associated gene)
chr13_-_33022372 2.47 ENSDART00000147165
RNA binding motif protein 25a
chr5_-_46980651 2.47 ENSDART00000181022
ENSDART00000168038
EGF-like repeats and discoidin I-like domains 3a
chr10_-_17103651 2.46 ENSDART00000108959
ring finger protein 208
chr3_+_29980603 2.44 ENSDART00000151509
potassium voltage-gated channel, shaker-related subfamily, member 7
chr8_+_25351863 2.40 ENSDART00000034092
deoxyribonuclease I-like 1-like
chr6_-_11768198 2.38 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr24_+_29449690 2.35 ENSDART00000105743
ENSDART00000193556
ENSDART00000145816
netrin g1a
chr9_-_49493305 2.29 ENSDART00000148707
ENSDART00000148561
xin actin binding repeat containing 2b
chr20_+_1398564 2.25 ENSDART00000002242
liver-enriched gene 1, tandem duplicate 2
chr2_-_31302615 2.25 ENSDART00000034784
ENSDART00000060812
adenylate cyclase activating polypeptide 1b
chr18_+_910992 2.23 ENSDART00000161206
ENSDART00000167229
pyruvate kinase M1/2a
chr15_+_45640906 2.19 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr5_-_55395964 2.19 ENSDART00000145791
prune homolog 2 (Drosophila)
chr12_+_7491690 2.18 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr3_+_40170216 2.10 ENSDART00000011568
synaptogyrin 3a
chr24_-_39610585 2.10 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr1_-_22757145 2.10 ENSDART00000134719
prominin 1 b
chr12_-_47782623 2.08 ENSDART00000115742
selenoprotein U1b
chr3_+_13440900 2.08 ENSDART00000143715
si:dkey-117i10.1
chr11_-_24681292 2.08 ENSDART00000089601
olfactomedin-like 3b
chr20_+_13969414 2.08 ENSDART00000049864
retinal degeneration 3
chr9_+_4429593 2.07 ENSDART00000184855

chr9_-_48736388 2.06 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr20_+_22681066 2.00 ENSDART00000143286
ligand of numb-protein X 1
chr5_-_23280098 1.98 ENSDART00000126540
ENSDART00000051533
proteolipid protein 1b
chr7_-_38638809 1.97 ENSDART00000144341
six-cysteine containing astacin protease 4
chr6_+_3828560 1.97 ENSDART00000185273
ENSDART00000179091
glutamate decarboxylase 1b
chr7_-_13882988 1.94 ENSDART00000169828
retinaldehyde binding protein 1a
chr4_-_4387012 1.94 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr15_-_12500938 1.93 ENSDART00000159627
sodium channel, voltage-gated, type IV, beta a
chr25_+_13406069 1.92 ENSDART00000010495
zinc and ring finger 1
chr7_+_568819 1.91 ENSDART00000173716
neurexin 2b
chr17_-_40397752 1.89 ENSDART00000178483

chr17_+_51499789 1.88 ENSDART00000187701

chr10_-_31782616 1.87 ENSDART00000128839
fasciculation and elongation protein zeta 1 (zygin I)
chr1_-_30039331 1.84 ENSDART00000086935
ENSDART00000143800
zgc:153256
chr3_-_27880229 1.84 ENSDART00000151404
4-aminobutyrate aminotransferase
chr20_-_25518488 1.84 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr3_-_28120092 1.83 ENSDART00000151143
RNA binding fox-1 homolog 1
chr12_+_18556929 1.82 ENSDART00000191277

chr25_+_3326885 1.82 ENSDART00000104866
lactate dehydrogenase Bb
chr9_+_4306122 1.82 ENSDART00000193722
ENSDART00000190521
kalirin RhoGEF kinase a
chr6_-_31348999 1.82 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr22_+_19290199 1.82 ENSDART00000148173
si:dkey-21e2.15
chr12_-_48992527 1.79 ENSDART00000169696
cadherin related family member 1
chr2_-_5502256 1.79 ENSDART00000193037
S-antigen; retina and pineal gland (arrestin) a
chr9_+_29643036 1.76 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr18_-_33344 1.75 ENSDART00000129125
phosphodiesterase 8A
chr9_-_22057658 1.74 ENSDART00000101944
crystallin, gamma MX, like 1
chr9_+_42095220 1.74 ENSDART00000148317
ENSDART00000134431
poly(rC) binding protein 3
chr5_-_68916455 1.72 ENSDART00000171465
ankyrin 1, erythrocytic a
chr5_-_30079434 1.72 ENSDART00000133981
beta-carotene oxygenase 2a
chr9_-_9982696 1.72 ENSDART00000192548
ENSDART00000125852
UDP glucuronosyltransferase 1 family a, b
chr2_-_44720551 1.71 ENSDART00000146380
MAP6 domain containing 1
chr8_+_24854600 1.71 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr11_+_45287541 1.71 ENSDART00000165321
ENSDART00000173116
pyrroline-5-carboxylate reductase 1b
chr18_-_16179129 1.70 ENSDART00000125353
solute carrier family 6 (neutral amino acid transporter), member 15
chr3_-_32170850 1.69 ENSDART00000055307
ENSDART00000157366
troponin T type 1 (skeletal, slow)
chr12_+_35119762 1.69 ENSDART00000085774
si:ch73-127m5.1
chr3_-_5829501 1.68 ENSDART00000091017
protein kinase N1b
chr1_-_22756898 1.67 ENSDART00000158915
prominin 1 b
chr19_-_703898 1.66 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr23_+_21966447 1.66 ENSDART00000189378
lactamase, beta-like 1a
chr16_-_12688957 1.65 ENSDART00000147854
ENSDART00000184587
microfibril associated protein 5
chr2_-_24289641 1.65 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr21_-_14251306 1.65 ENSDART00000114715
ENSDART00000181380
mannosidase, alpha, class 1B, member 1a
chr23_-_8373676 1.64 ENSDART00000105135
ENSDART00000158531
opiate receptor-like 1
chr25_+_16945348 1.62 ENSDART00000016591
fibroblast growth factor 6a
chr11_+_36989696 1.62 ENSDART00000045888
transketolase a
chr5_+_38276582 1.61 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_+_42191592 1.61 ENSDART00000144716
caveolae associated protein 4a
chr15_-_28095532 1.60 ENSDART00000191490
crystallin, beta A1a
chr21_-_39546737 1.59 ENSDART00000006971
septin 4a
chr3_+_1015867 1.59 ENSDART00000109912
si:ch1073-464p5.5
chr3_-_30061985 1.58 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr18_+_8340886 1.58 ENSDART00000081132
carnitine palmitoyltransferase 1B (muscle)
chr6_+_13806466 1.57 ENSDART00000043522
transmembrane protein 198b
chr10_+_17026870 1.57 ENSDART00000184529
ENSDART00000157480

chr22_+_19311411 1.57 ENSDART00000133234
ENSDART00000138284
si:dkey-21e2.16
chr3_-_30941362 1.56 ENSDART00000076830
coronin, actin binding protein, 1A
chr25_-_19374710 1.56 ENSDART00000184483
ENSDART00000188706
microtubule-associated protein 1Ab
chr3_-_1317290 1.56 ENSDART00000047094

chr17_-_25395395 1.56 ENSDART00000170233
family with sequence similarity 167, member B
chr20_-_39273987 1.55 ENSDART00000127173
clusterin
chr3_+_30257582 1.55 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr6_-_40722480 1.55 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr11_+_43401592 1.54 ENSDART00000112468
vasoactive intestinal peptide b
chr18_+_783936 1.54 ENSDART00000193357
ribonuclease P and MRP subunit p25, b
chr11_-_6048490 1.54 ENSDART00000066164
plasmalemma vesicle associated protein b
chr3_+_34821327 1.53 ENSDART00000055262
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr2_+_28672152 1.53 ENSDART00000157410
ENSDART00000169614
NAD synthetase 1
chr16_+_31802203 1.53 ENSDART00000058739
ENSDART00000110834
wingless-type MMTV integration site family, member 4b
chr11_+_42730639 1.53 ENSDART00000165297
zgc:194981
chr1_+_34496855 1.52 ENSDART00000012873
Kruppel-like factor 12a
chr6_+_9175886 1.51 ENSDART00000165333
si:ch211-207l14.1
chr14_+_21699414 1.50 ENSDART00000169942
syntaxin 3A
chr6_+_12853655 1.50 ENSDART00000156341
family with sequence similarity 117, member Ba
chr13_+_50375800 1.50 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr12_+_46708920 1.50 ENSDART00000153089
exocyst complex component 7
chr18_-_14937211 1.50 ENSDART00000141893
megalencephalic leukoencephalopathy with subcortical cysts 1
chr21_+_40106448 1.49 ENSDART00000100166
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr18_+_23249519 1.48 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
myocyte enhancer factor 2aa
chr7_+_34297271 1.48 ENSDART00000180342
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr17_-_52595932 1.48 ENSDART00000127225
si:ch211-173a9.7
chr21_+_11415224 1.47 ENSDART00000049036
zgc:92275
chr17_-_31058900 1.47 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
echinoderm microtubule associated protein like 1
chr8_+_24861264 1.47 ENSDART00000099607
solute carrier family 6 (neutral amino acid transporter), member 17
chr20_-_24122881 1.46 ENSDART00000131857
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
chr18_+_3530769 1.45 ENSDART00000163469
si:ch73-338a16.3
chr6_+_55032439 1.45 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
myosin binding protein Hb
chr10_-_30785501 1.45 ENSDART00000020054
opioid binding protein/cell adhesion molecule-like
chr21_-_39639954 1.43 ENSDART00000026766
aldolase C, fructose-bisphosphate, b
chr16_+_29650698 1.43 ENSDART00000137153
tropomodulin 4 (muscle)
chr19_+_58954 1.42 ENSDART00000162379
collagen, type XIV, alpha 1b
chr2_-_10062575 1.41 ENSDART00000091726
family with sequence similarity 78, member B a
chr1_-_14332283 1.40 ENSDART00000090025
Wolfram syndrome 1a (wolframin)
chr3_-_28828569 1.40 ENSDART00000167679
si:ch211-76l23.4
chr13_-_16222388 1.39 ENSDART00000182861
zgc:110045
chr4_+_10366532 1.38 ENSDART00000189901
potassium voltage-gated channel, Shal-related subfamily, member 2
chr9_-_31747106 1.38 ENSDART00000048469
ENSDART00000145204
ENSDART00000186889
sodium leak channel, non-selective
chr16_-_17175731 1.38 ENSDART00000183057
opsin 9
chr13_+_22480496 1.37 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
LIM domain binding 3a
chr23_-_15216654 1.36 ENSDART00000131649
sulfatase 2b
chr6_-_47246948 1.36 ENSDART00000162435
glutamate receptor, metabotropic 4
chr3_+_42923275 1.35 ENSDART00000168228
transmembrane protein 184a
chr9_-_22821901 1.34 ENSDART00000101711
nebulin
chr11_+_45286911 1.34 ENSDART00000181763
pyrroline-5-carboxylate reductase 1b
chr1_+_54626491 1.34 ENSDART00000136063
si:ch211-202h22.9
chr13_+_33703784 1.34 ENSDART00000173361
MACRO domain containing 2
chr6_-_60031693 1.33 ENSDART00000160275

chr21_-_2238277 1.33 ENSDART00000165754
si:dkey-50i6.6
chr12_-_43685802 1.32 ENSDART00000170723
zgc:112964
chr11_-_11471857 1.32 ENSDART00000030103
keratin 94
chr1_-_22512063 1.32 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6

Network of associatons between targets according to the STRING database.

First level regulatory network of esr1+esr2a+esr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
1.2 4.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.9 2.8 GO:1905072 cardiac jelly development(GO:1905072)
0.9 2.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.9 2.6 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.7 88.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.7 2.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.6 2.6 GO:0043084 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.6 3.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.6 3.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.6 3.9 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.5 3.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 2.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.5 2.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.5 2.8 GO:0006545 glycine biosynthetic process(GO:0006545)
0.4 1.8 GO:0015677 copper ion import(GO:0015677)
0.4 4.0 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 2.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 1.3 GO:2000812 positive regulation of protein depolymerization(GO:1901881) regulation of barbed-end actin filament capping(GO:2000812)
0.4 1.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.4 1.7 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.4 2.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.4 1.2 GO:0000256 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.4 1.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.4 6.2 GO:0006825 copper ion transport(GO:0006825)
0.3 4.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.3 1.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.3 1.3 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.3 3.4 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 1.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 0.9 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.3 1.2 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.3 0.9 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 1.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 1.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.3 1.0 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.2 1.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 1.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.7 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.2 5.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 2.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.2 3.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 2.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.6 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.8 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 3.7 GO:0042574 retinal metabolic process(GO:0042574)
0.2 1.6 GO:0019233 sensory perception of pain(GO:0019233)
0.2 1.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 1.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 2.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 5.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 0.6 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.2 2.6 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.6 GO:0072149 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.2 0.6 GO:0071733 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.9 GO:0071295 cellular response to nutrient(GO:0031670) vitamin D3 metabolic process(GO:0070640) cellular response to vitamin(GO:0071295) cellular response to vitamin D(GO:0071305)
0.2 0.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 3.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.7 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 2.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.4 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 2.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.4 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 2.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.3 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 1.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.8 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 1.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.8 GO:0070285 pigment cell development(GO:0070285)
0.1 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 2.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 5.2 GO:0007602 phototransduction(GO:0007602)
0.1 0.5 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 2.1 GO:0007634 optokinetic behavior(GO:0007634)
0.1 0.9 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 3.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.1 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 0.6 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.6 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.7 GO:0090075 relaxation of muscle(GO:0090075)
0.1 0.7 GO:0008343 adult feeding behavior(GO:0008343) negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 2.4 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.6 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.1 3.4 GO:0007586 digestion(GO:0007586)
0.1 2.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.4 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 2.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 1.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.6 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.0 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.3 GO:0010039 response to iron ion(GO:0010039)
0.1 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.2 GO:0033273 response to vitamin(GO:0033273)
0.1 0.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 7.8 GO:0051260 protein homooligomerization(GO:0051260)
0.1 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.4 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 2.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.6 GO:0090148 membrane fission(GO:0090148)
0.1 2.2 GO:0006096 glycolytic process(GO:0006096)
0.1 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 2.1 GO:0050433 catecholamine secretion(GO:0050432) regulation of catecholamine secretion(GO:0050433)
0.1 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.3 GO:0035777 pronephric distal tubule development(GO:0035777)
0.1 4.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.5 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.3 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.8 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 1.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.4 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.8 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0098773 skin epidermis development(GO:0098773)
0.0 1.1 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.5 GO:0001964 startle response(GO:0001964)
0.0 0.3 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.8 GO:0050926 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 1.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 2.2 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 3.8 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.6 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.0 3.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.2 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0000423 macromitophagy(GO:0000423)
0.0 1.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.4 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 2.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 1.0 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 3.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.8 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940) adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0046184 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 1.2 GO:0031638 zymogen activation(GO:0031638)
0.0 0.9 GO:0043113 receptor clustering(GO:0043113)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.9 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.4 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.6 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 1.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 1.6 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 1.9 GO:0007626 locomotory behavior(GO:0007626)
0.0 1.7 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.3 GO:0006813 potassium ion transport(GO:0006813)
0.0 2.3 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 1.0 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.9 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.4 GO:0006887 exocytosis(GO:0006887)
0.0 0.2 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 1.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094) response to alkaloid(GO:0043279)
0.0 1.3 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.2 GO:0050808 synapse organization(GO:0050808)
0.0 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.6 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.6 2.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 3.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.5 4.0 GO:0071914 prominosome(GO:0071914)
0.3 4.2 GO:0031045 dense core granule(GO:0031045)
0.3 2.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.6 GO:0042583 chromaffin granule(GO:0042583)
0.3 1.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 17.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 2.6 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.2 1.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 3.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.0 GO:0032433 filopodium tip(GO:0032433)
0.2 0.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 7.3 GO:0043204 perikaryon(GO:0043204)
0.2 7.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 0.8 GO:0097224 sperm connecting piece(GO:0097224)
0.1 6.2 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 2.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.0 GO:0043209 myelin sheath(GO:0043209)
0.1 2.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.4 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 5.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 5.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 3.9 GO:0043025 neuronal cell body(GO:0043025)
0.1 2.6 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 3.2 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.1 GO:0031430 M band(GO:0031430)
0.1 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.2 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.8 GO:0043195 terminal bouton(GO:0043195)
0.0 2.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 7.2 GO:0030424 axon(GO:0030424)
0.0 1.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0098845 postsynaptic recycling endosome(GO:0098837) postsynaptic endosome(GO:0098845)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 4.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 5.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0034704 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.1 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 5.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 5.9 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0099503 secretory vesicle(GO:0099503)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
1.2 6.2 GO:0016531 copper chaperone activity(GO:0016531)
1.2 3.7 GO:0048030 disaccharide binding(GO:0048030)
1.1 3.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
1.0 87.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 4.1 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.8 11.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.7 7.0 GO:0016936 galactoside binding(GO:0016936)
0.7 3.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.7 2.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 1.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 0.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.6 2.2 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.5 2.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 1.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 3.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.3 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.4 2.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 2.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 2.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.3 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 1.7 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 1.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3 3.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 0.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3 3.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 1.2 GO:0050897 cobalt ion binding(GO:0050897)
0.3 2.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.3 2.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 1.6 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.3 2.6 GO:0030332 cyclin binding(GO:0030332)
0.3 2.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 5.9 GO:0008483 transaminase activity(GO:0008483)
0.2 1.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 3.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 8.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.9 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 0.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.8 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.9 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 1.7 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.6 GO:0004985 opioid receptor activity(GO:0004985)
0.2 0.9 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 6.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 1.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 6.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 3.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 4.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.4 GO:0031704 apelin receptor binding(GO:0031704)
0.1 2.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 2.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 1.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.9 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 5.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 2.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 1.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 1.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 1.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 2.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.0 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 4.3 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.9 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 9.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.9 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.6 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.6 GO:0009975 cyclase activity(GO:0009975)
0.1 0.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.8 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 5.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0001221 transcription cofactor binding(GO:0001221) transcription corepressor binding(GO:0001222)
0.0 1.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 2.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 1.0 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 6.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0008443 6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443)
0.0 3.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 3.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 5.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.1 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 7.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.6 GO:0005267 potassium channel activity(GO:0005267)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 2.7 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:1900750 oligopeptide binding(GO:1900750)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 3.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 5.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.1 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 2.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 5.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 1.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 7.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 2.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.2 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 1.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 6.7 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 2.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 4.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 4.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis