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PRJEB1986: zebrafish developmental stages transcriptome

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Results for en1a

Z-value: 0.75

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Transcription factors associated with en1a

Gene Symbol Gene ID Gene Info
ENSDARG00000014321 engrailed homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
en1adr11_v1_chr9_-_785444_7854440.302.1e-01Click!

Activity profile of en1a motif

Sorted Z-values of en1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_9277152 1.41 ENSDART00000189048
ankyrin repeat and SOCS box-containing 12b
chr5_+_22459087 1.37 ENSDART00000134781

chr10_+_28428222 1.32 ENSDART00000135003
si:ch211-222e20.4
chr7_-_17297156 1.15 ENSDART00000161336
novel immune-type receptor 11a
chr14_-_41467497 1.01 ENSDART00000181220
MID1 interacting protein 1, like
chr7_+_55314206 0.91 ENSDART00000132852
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr7_+_17120811 0.89 ENSDART00000147140
protein arginine methyltransferase 3
chr17_-_6349044 0.85 ENSDART00000081707
organic cation transporter 2
chr7_-_20582842 0.84 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
chr10_-_21542702 0.83 ENSDART00000146761
ENSDART00000134502
zgc:165539
chr16_-_41535690 0.81 ENSDART00000102662
ribonuclease P/MRP 25 subunit-like
chr18_+_19456648 0.80 ENSDART00000079695
zwilch kinetochore protein
chr22_+_2183110 0.80 ENSDART00000159279
ENSDART00000121703
zinc finger protein 1152
chr3_+_23768898 0.76 ENSDART00000110682
homeobox B1a
chr3_-_26184018 0.75 ENSDART00000191604
si:ch211-11k18.4
chr5_-_65021736 0.75 ENSDART00000162368
ENSDART00000161876
annexin A1c
chr11_-_669558 0.74 ENSDART00000173450
peroxisome proliferator-activated receptor gamma
chr4_-_52165969 0.72 ENSDART00000171130
si:dkeyp-44b5.4
chr10_+_38512270 0.69 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr2_-_26590628 0.69 ENSDART00000025120
NDC1 transmembrane nucleoporin
chr17_-_18797245 0.68 ENSDART00000045991
vaccinia related kinase 1
chr25_-_3836597 0.68 ENSDART00000115154
si:ch211-247i17.1
chr18_-_43866526 0.66 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr7_+_4592867 0.66 ENSDART00000192614
si:dkey-83f18.15
chr1_-_18585046 0.66 ENSDART00000147228
family with sequence similarity 114, member A1
chr7_-_18712482 0.66 ENSDART00000173517
ENSDART00000122564
ENSDART00000173905
tRNA methyltransferase 10A
chr20_+_51833030 0.65 ENSDART00000074330
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr9_+_44994214 0.65 ENSDART00000141434
retinol saturase (all-trans-retinol 13,14-reductase) like
chr12_+_27096835 0.65 ENSDART00000149475
tubulin tyrosine ligase-like family, member 6
chr22_+_17120473 0.64 ENSDART00000170076
ENSDART00000090217
Fras1 related extracellular matrix 1b
chr12_-_10365875 0.64 ENSDART00000142386
ENSDART00000007335
NDC80 kinetochore complex component
chr8_-_50888806 0.63 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr6_+_21684296 0.62 ENSDART00000057223
Ras homolog, mTORC1 binding like 1
chr2_+_36606019 0.62 ENSDART00000098415
inhibitor of growth family, member 5b
chr7_-_6470431 0.62 ENSDART00000081359
zgc:110425
chr12_-_10381282 0.60 ENSDART00000152788
marker of proliferation Ki-67
chr22_-_10440688 0.60 ENSDART00000111962
nucleolar protein 8
chr9_-_33121535 0.60 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr11_+_3989403 0.59 ENSDART00000082379
signal peptidase complex subunit 1
chr11_-_35756468 0.59 ENSDART00000103076
ADP-ribosylation factor-like 8Bb
chr22_+_18349794 0.59 ENSDART00000186580
GATA zinc finger domain containing 2Ab
chr24_+_18299175 0.59 ENSDART00000140994
thiamin pyrophosphokinase 1
chr1_+_49682312 0.58 ENSDART00000136747
si:ch211-149l1.2
chr3_+_14543953 0.58 ENSDART00000161710
erythropoietin receptor
chr9_+_21277846 0.58 ENSDART00000139620
ENSDART00000110996
ENSDART00000111899
large tumor suppressor kinase 2
chr24_-_2423791 0.57 ENSDART00000190402
ras responsive element binding protein 1a
chr13_+_18311410 0.55 ENSDART00000036718
ENSDART00000132073
eukaryotic translation initiation factor 4E family member 1c
chr12_+_34119439 0.55 ENSDART00000032821
cytohesin 1b
chr18_+_41232719 0.55 ENSDART00000138552
ENSDART00000145863
thyroid hormone receptor interactor 12
chr10_-_36633882 0.55 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr8_-_39859688 0.55 ENSDART00000019907
unc-119 homolog 1
chr23_+_42396934 0.55 ENSDART00000169821
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr23_-_16981899 0.54 ENSDART00000125472
ENSDART00000142297
ENSDART00000143180
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr2_-_24398324 0.54 ENSDART00000165226
zgc:154006
chr19_+_12649691 0.54 ENSDART00000192956
ENSDART00000088917
RNA (guanine-7-) methyltransferase
chr5_-_8164439 0.51 ENSDART00000189912
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr1_-_38170997 0.51 ENSDART00000142811
high mobility group box 2a
chr8_+_40284973 0.50 ENSDART00000018401
ORAI calcium release-activated calcium modulator 1a
chr5_-_69716501 0.50 ENSDART00000158956
MOB kinase activator 1A
chr4_-_4250317 0.49 ENSDART00000103316
CD9 molecule b
chr16_+_23924040 0.48 ENSDART00000161124
si:dkey-7f3.14
chr4_-_72296520 0.47 ENSDART00000182638
si:cabz01071911.3
chr7_+_69459759 0.47 ENSDART00000160500
CTD nuclear envelope phosphatase 1b
chr4_-_55039830 0.47 ENSDART00000170096
si:dkey-56m15.3
chr2_+_37836821 0.47 ENSDART00000143203
poly (ADP-ribose) polymerase 2
chr13_+_8892784 0.46 ENSDART00000075054
ENSDART00000143705
thyroid adenoma associated
chr9_+_23003208 0.45 ENSDART00000021060
ELL associated factor 2
chr2_+_44972720 0.44 ENSDART00000075146
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr2_-_3045861 0.43 ENSDART00000105818
ENSDART00000187575
guanylate kinase 1a
chr11_-_6880725 0.43 ENSDART00000007204
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr2_+_26656283 0.43 ENSDART00000133202
ENSDART00000099208
aspartate beta-hydroxylase
chr23_+_27782071 0.43 ENSDART00000131379
lysine (K)-specific methyltransferase 2D
chr18_-_17513426 0.42 ENSDART00000146725
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr23_-_10722664 0.41 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
forkhead box P1a
chr7_-_39751540 0.40 ENSDART00000016803
GrpE-like 1, mitochondrial
chr6_+_47424266 0.40 ENSDART00000171087
si:ch211-286o17.1
chr5_+_61863996 0.40 ENSDART00000082879
symplekin
chr2_+_22495274 0.40 ENSDART00000167915
leucine rich repeat containing 8 VRAC subunit Da
chr18_-_14901437 0.39 ENSDART00000145842
ENSDART00000008035
TraB domain containing
chr21_+_25198637 0.39 ENSDART00000164972
si:dkey-183i3.6
chr3_+_26345732 0.39 ENSDART00000128613
ribosomal protein S15a
chr22_-_37738203 0.39 ENSDART00000143190
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr23_-_25779995 0.39 ENSDART00000110670
si:dkey-21c19.3
chr7_-_34062301 0.39 ENSDART00000052404
mitogen-activated protein kinase kinase 5
chr25_-_17503393 0.39 ENSDART00000061726
tripartite motif containing 35-40
chr2_+_22531185 0.39 ENSDART00000171959
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr4_-_20108833 0.39 ENSDART00000100867
family with sequence similarity 3, member C
chr15_-_20233105 0.38 ENSDART00000123910
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr22_+_22303053 0.38 ENSDART00000129975
secretory carrier membrane protein 4
chr14_+_14043793 0.37 ENSDART00000164376
Ras-related GTP binding A
chr1_-_11913170 0.37 ENSDART00000165543
G protein-coupled receptor kinase 4
chr22_+_15973122 0.37 ENSDART00000144545
ring finger and CCCH-type domains 1a
chr23_-_33738945 0.37 ENSDART00000136386
si:ch211-210c8.7
chr22_-_37007365 0.37 ENSDART00000157966
si:dkey-211e20.10
chr8_+_17168114 0.37 ENSDART00000183901
centromere protein H
chr12_-_8070969 0.37 ENSDART00000020995
transmembrane protein 26b
chr17_-_45734459 0.36 ENSDART00000137807
ADP-ribosylation factor 6b
chr14_+_45732081 0.36 ENSDART00000110103
coiled-coil domain containing 88B
chr25_+_19095231 0.35 ENSDART00000154066
interferon stimulated exonuclease gene
chr6_-_8392104 0.35 ENSDART00000081561
ENSDART00000181178
interleukin enhancer binding factor 3a
chr10_+_16165533 0.35 ENSDART00000065045
proline-rich coiled-coil 1
chr4_+_13615731 0.35 ENSDART00000141395
ENSDART00000144310
coiled-coil domain containing 87
chr18_-_29898351 0.35 ENSDART00000138533
ENSDART00000064076
C-x(9)-C motif containing 2
chr25_+_7532627 0.35 ENSDART00000187660
phosphatidylserine synthase 2
chr14_-_25935167 0.34 ENSDART00000139855
GTPase activating protein (SH3 domain) binding protein 1
chr13_-_1130096 0.34 ENSDART00000010261
partner of NOB1 homolog
chr4_+_25912654 0.34 ENSDART00000109508
ENSDART00000134218
vezatin, adherens junctions transmembrane protein
chr9_-_30555725 0.34 ENSDART00000079222
chromatin assembly factor 1, subunit B
chr1_-_57172294 0.33 ENSDART00000063774
Rac family small GTPase 1, like
chr12_+_36416173 0.33 ENSDART00000190278
unkempt family zinc finger
chr11_-_44898129 0.33 ENSDART00000157615
eukaryotic translation initiation factor 4A3
chr2_-_16562505 0.33 ENSDART00000156406
ATPase Na+/K+ transporting subunit beta 3a
chr13_+_25364324 0.33 ENSDART00000187471
conserved helix-loop-helix ubiquitous kinase
chr17_-_45734231 0.33 ENSDART00000074873
ADP-ribosylation factor 6b
chr6_-_54111928 0.32 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr19_-_32914227 0.32 ENSDART00000186115
ENSDART00000124246
metadherin a
chr8_-_21054132 0.32 ENSDART00000187735
zgc:112962
chr23_+_36653376 0.31 ENSDART00000053189
G protein-coupled receptor 182
chr16_-_45080812 0.31 ENSDART00000157377
si:rp71-77l1.2
chr2_+_26498446 0.31 ENSDART00000078412
ribosomal protein S8a
chr22_+_2409175 0.31 ENSDART00000141776
zgc:113220
chr15_-_26931541 0.31 ENSDART00000027563
coiled-coil domain containing 9
chr13_-_15700060 0.30 ENSDART00000170689
ENSDART00000010986
ENSDART00000101741
ENSDART00000139124
creatine kinase, brain a
chr2_+_36114194 0.30 ENSDART00000113547
T-cell receptor alpha joining 39
chr22_+_2533514 0.30 ENSDART00000147967
si:ch73-92e7.4
chr9_+_14152211 0.30 ENSDART00000148055
si:ch211-67e16.11
chr2_+_41524238 0.30 ENSDART00000122860
ENSDART00000017977
activin A receptor, type 1 like
chr20_-_48898560 0.30 ENSDART00000163071
5'-3' exoribonuclease 2
chr21_-_31252131 0.30 ENSDART00000121946
calcitonin gene-related peptide-receptor component protein
chr1_-_17689858 0.29 ENSDART00000181078
cilia and flagella associated protein 97
chr2_+_38025260 0.29 ENSDART00000075905
heterogeneous nuclear ribonucleoprotein C
chr1_-_38171648 0.29 ENSDART00000137451
ENSDART00000047159
high mobility group box 2a
chr23_+_1730663 0.29 ENSDART00000149545
transglutaminase 1, K polypeptide
chr5_-_41996414 0.29 ENSDART00000143573
nuclear receptor corepressor 1
chr25_-_13023569 0.28 ENSDART00000167232
chemokine (C-C motif) ligand 39, duplicate 1
chr2_-_24554416 0.28 ENSDART00000052061
calponin 2
chr25_+_17589906 0.27 ENSDART00000167750
vac14 homolog (S. cerevisiae)
chr6_+_18544791 0.27 ENSDART00000167463
ENSDART00000169599
ATPase family, AAA domain containing 5b
chr8_-_22531817 0.27 ENSDART00000140606
cold shock domain containing E1, RNA-binding
chr8_-_13211527 0.27 ENSDART00000090541
si:ch73-61d6.3
chr20_-_14718801 0.27 ENSDART00000137605
SUN domain containing ossification factor
chr3_+_12784460 0.26 ENSDART00000168382
cytochrome P450, family 2, subfamily K, polypeptide 8
chr18_-_7422787 0.26 ENSDART00000081386
si:dkey-30c15.12
chr9_-_25255490 0.26 ENSDART00000141502
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr11_-_3907937 0.26 ENSDART00000082409
ribophorin I
chr5_-_55625247 0.26 ENSDART00000133156
heterogeneous nuclear ribonucleoprotein K, like
chr6_+_41446541 0.26 ENSDART00000029553
ENSDART00000128756
ENSDART00000144864
REM2 and RAB-like small GTPase 1
chr15_+_23799461 0.25 ENSDART00000154885
si:ch211-167j9.4
chr19_+_7495791 0.25 ENSDART00000010862
mitochondrial ribosomal protein L24
chr14_-_38872536 0.25 ENSDART00000184315
ENSDART00000127479
glutathione reductase
chr16_+_23383316 0.25 ENSDART00000103220
keratinocyte associated protein 2
chr14_-_21123551 0.24 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr12_+_17754859 0.24 ENSDART00000112119
basic helix-loop-helix family, member a15
chr11_+_24716837 0.24 ENSDART00000145217
zgc:153953
chr5_-_13778726 0.24 ENSDART00000051655
small nuclear ribonucleoprotein 27 (U4/U6.U5)
chr22_+_36547670 0.24 ENSDART00000125991
ENSDART00000186372
armadillo repeat containing 9
chr22_-_20733822 0.24 ENSDART00000133780
si:dkey-3k20.1
chr5_-_28038623 0.24 ENSDART00000160013
zgc:113436
chr1_-_11607062 0.24 ENSDART00000158253
si:dkey-26i13.6
chr4_+_25912308 0.23 ENSDART00000167845
ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr4_-_64912026 0.23 ENSDART00000157956
si:ch211-234c11.2
chr14_+_26247319 0.23 ENSDART00000192793
coiled-coil domain containing 69
chr8_+_17167876 0.23 ENSDART00000134665
centromere protein H
chr2_-_37837056 0.22 ENSDART00000158179
ENSDART00000160317
ENSDART00000171409
methyltransferase like 17
chr19_-_10810006 0.22 ENSDART00000151157
si:dkey-3n22.9
chr15_-_45246911 0.22 ENSDART00000189557
ENSDART00000185291

chr1_+_14406098 0.22 ENSDART00000030083
cysteine-rich hydrophobic domain 2
chr4_-_71983381 0.22 ENSDART00000169130
finTRIM family, member 64
chr2_+_49631850 0.22 ENSDART00000114274
ENSDART00000114516
si:dkey-53k12.18
chr3_-_3939785 0.22 ENSDART00000049593
un-named sa1506
chr14_+_16813816 0.22 ENSDART00000161201
LIM and calponin homology domains 1b
chr1_+_33647682 0.22 ENSDART00000114384
zinc finger protein 654
chr3_+_16663373 0.21 ENSDART00000100961
zgc:55558
chr9_+_13733468 0.21 ENSDART00000165954
ENSDART00000160355
ENSDART00000081040
ENSDART00000138254
ENSDART00000081015
ENSDART00000141314
abl-interactor 2a
chr20_-_39391833 0.21 ENSDART00000135149
si:dkey-217m5.8
chr3_-_9738985 0.21 ENSDART00000160102

chr3_+_3519607 0.21 ENSDART00000150922
CDC42 effector protein (Rho GTPase binding) 1b
chr22_+_1285182 0.21 ENSDART00000171750
si:ch73-138e16.3
chr25_+_17590095 0.21 ENSDART00000009767
vac14 homolog (S. cerevisiae)
chr2_-_22530969 0.20 ENSDART00000159641
zinc finger protein 644a
chr16_-_23885482 0.20 ENSDART00000132243
oxidative stress induced growth inhibitor family member 2
chr7_-_34265481 0.20 ENSDART00000173596
si:ch211-98n17.5
chr1_-_45616242 0.20 ENSDART00000150066
activating transcription factor 7 interacting protein
chr23_+_30736895 0.20 ENSDART00000042944
additional sex combs like transcriptional regulator 1
chr4_+_65332578 0.20 ENSDART00000170824
zinc finger protein 1108
chr21_-_21824285 0.19 ENSDART00000030984
WD repeat domain 73
chr20_-_20312789 0.19 ENSDART00000114779
si:ch211-212g7.6
chr21_-_21570134 0.19 ENSDART00000174388
odorant receptor, family H, subfamily 133, member 4
chr12_+_1385192 0.19 ENSDART00000160788
phosphatidylethanolamine N-methyltransferase
chr4_-_28958601 0.19 ENSDART00000111294
zgc:174315
chr1_+_39597809 0.19 ENSDART00000122700
teneurin transmembrane protein 3
chr17_-_12407106 0.19 ENSDART00000183540
ankyrin repeat and EF-hand domain containing 1b
chr9_+_55857193 0.18 ENSDART00000160980
septin 10
chr13_+_22476742 0.18 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
LIM domain binding 3a
chr4_-_5831522 0.18 ENSDART00000008898
forkhead box M1
chr9_+_3175201 0.18 ENSDART00000179022
ENSDART00000007756
ENSDART00000182108
dynein, cytoplasmic 1, intermediate chain 2a
chr6_+_35052721 0.18 ENSDART00000191090
ENSDART00000082940
U2AF homology motif (UHM) kinase 1
chr19_+_9091673 0.18 ENSDART00000052898
si:ch211-81a5.5
chr20_-_37813863 0.17 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr2_+_3201345 0.17 ENSDART00000130349
wingless-type MMTV integration site family, member 9A

Network of associatons between targets according to the STRING database.

First level regulatory network of en1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005991 trehalose metabolic process(GO:0005991)
0.2 0.6 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 0.6 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.2 0.7 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.2 0.9 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.8 GO:0002825 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.1 0.8 GO:0021661 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.1 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.4 GO:0044003 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.1 0.5 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.8 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.4 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.1 0.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.9 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.6 GO:0046620 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.0 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 1.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.2 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.3 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.3 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.2 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.7 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.8 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.3 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.4 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.5 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.3 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.2 GO:0016460 myosin II complex(GO:0016460)
0.1 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.2 0.6 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.2 0.7 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.2 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.9 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.6 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0004532 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC