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PRJEB1986: zebrafish developmental stages transcriptome

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Results for emx2+emx3

Z-value: 1.01

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Transcription factors associated with emx2+emx3

Gene Symbol Gene ID Gene Info
ENSDARG00000020417 empty spiracles homeobox 3
ENSDARG00000039701 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
emx3dr11_v1_chr14_-_26377044_26377044-0.861.8e-06Click!
emx2dr11_v1_chr13_+_19322686_19322686-0.652.7e-03Click!

Activity profile of emx2+emx3 motif

Sorted Z-values of emx2+emx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_34896956 2.92 ENSDART00000055415
peripherin 2a (retinal degeneration, slow)
chr5_+_2815021 2.61 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr7_-_38638809 2.54 ENSDART00000144341
six-cysteine containing astacin protease 4
chr14_+_45675306 2.47 ENSDART00000105461
retinal outer segment membrane protein 1b
chr7_-_38638276 2.30 ENSDART00000074463
six-cysteine containing astacin protease 4
chr25_+_14092871 2.27 ENSDART00000067239
guanylate cyclase activator 1g
chr17_-_12336987 2.01 ENSDART00000172001
synaptosomal-associated protein, 25b
chr6_+_39905021 2.00 ENSDART00000064904
endonuclease, polyU-specific
chr25_+_31227747 1.93 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr25_+_34984333 1.73 ENSDART00000154760
coiled-coil domain containing 136b
chr10_+_45089820 1.73 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr23_-_306796 1.71 ENSDART00000143125
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr8_-_23780334 1.70 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr6_+_612594 1.66 ENSDART00000150903
kynureninase
chr20_-_40755614 1.63 ENSDART00000061247
connexin 32.3
chr19_+_43297546 1.57 ENSDART00000168002
lysosomal protein transmembrane 5
chr15_+_45640906 1.56 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr16_-_38118003 1.55 ENSDART00000058667
si:dkey-23o4.6
chr9_-_22099536 1.54 ENSDART00000101923

chr3_-_32169754 1.50 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr11_+_6819050 1.49 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr4_+_25654686 1.48 ENSDART00000100714
acyl-CoA thioesterase 16
chr6_-_39344259 1.48 ENSDART00000104074
zgc:158846
chr21_+_10739846 1.44 ENSDART00000084011
complexin 4a
chr23_-_25976656 1.43 ENSDART00000019519
adenosine deaminase
chr5_+_37068223 1.33 ENSDART00000164279
si:dkeyp-110c7.4
chr15_-_14625373 1.31 ENSDART00000171841
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr5_-_24238733 1.30 ENSDART00000138170
phospholipid scramblase 3a
chr18_+_26829086 1.30 ENSDART00000098356
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr18_+_45483282 1.23 ENSDART00000183725
cyclic nucleotide gated channel beta 1a
chr7_+_23515966 1.23 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr15_+_36457888 1.22 ENSDART00000155100
si:dkey-262k9.2
chr21_-_22115136 1.20 ENSDART00000134715
ENSDART00000089246
ENSDART00000139789
ELMO/CED-12 domain containing 1
chr1_-_47071979 1.20 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr14_+_46313396 1.17 ENSDART00000047525
crystallin, beta A1, like 1
chr18_-_898870 1.17 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr4_+_11384891 1.14 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
piccolo presynaptic cytomatrix protein a
chr9_-_22147567 1.13 ENSDART00000110941
crystallin, gamma M2d14
chr3_-_59297532 1.08 ENSDART00000187991

chr21_+_21195487 1.06 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr9_-_22182396 1.05 ENSDART00000101809
crystallin, gamma M2d6
chr6_-_12851888 1.01 ENSDART00000056764
bone morphogenetic protein receptor, type II a (serine/threonine kinase)
chr10_+_17776981 1.00 ENSDART00000141693
chemokine (C-C motif) ligand 19b
chr5_+_30624183 0.99 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr18_+_8833251 0.97 ENSDART00000143519
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr8_+_17009199 0.97 ENSDART00000139452
phosphodiesterase 4D, cAMP-specific
chr10_+_21522545 0.94 ENSDART00000131097

chr1_-_21901589 0.93 ENSDART00000140553
FERM and PDZ domain containing 1a
chr18_+_26829362 0.93 ENSDART00000132728
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr21_-_20939488 0.91 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr4_-_69189894 0.86 ENSDART00000169596
si:ch211-209j12.1
chr18_-_6477662 0.86 ENSDART00000161263
IQ motif and Sec7 domain 3b
chr7_+_15659280 0.85 ENSDART00000173414
myocyte enhancer factor 2ab
chr22_+_19277361 0.84 ENSDART00000190075
ENSDART00000141097
ENSDART00000136943
si:dkey-21e2.13
chr21_-_4923427 0.83 ENSDART00000181489
potassium channel, subfamily T, member 1
chr12_-_17712393 0.83 ENSDART00000143534
ENSDART00000010144
parvalbumin 2
chr9_+_54039006 0.83 ENSDART00000112441
toll-like receptor 7
chr6_+_57541776 0.82 ENSDART00000157330
N-terminal EF-hand calcium binding protein 3
chr14_-_8890437 0.82 ENSDART00000167242
si:ch73-45o6.2
chr23_-_1660708 0.82 ENSDART00000175138

chr8_+_42917515 0.81 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr21_-_22827548 0.81 ENSDART00000079161
angiopoietin-like 5
chr11_+_45110865 0.80 ENSDART00000158188
meningioma expressed antigen 5 (hyaluronidase) like
chr20_+_52389858 0.80 ENSDART00000185863
ENSDART00000166651
Rho GTPase activating protein 39
chr9_-_54001502 0.80 ENSDART00000085253
midline 1
chr5_-_71705191 0.80 ENSDART00000187767
adenylate kinase 1
chr12_-_30523216 0.79 ENSDART00000152896
ENSDART00000153191
pleckstrin homology domain containing, family S member 1
chr20_-_1141722 0.79 ENSDART00000152675
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr13_+_7665890 0.78 ENSDART00000046792
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr2_+_20430366 0.78 ENSDART00000155108
si:ch211-153l6.6
chr20_+_34717403 0.78 ENSDART00000034252
prepronociceptin b
chr15_-_5740358 0.77 ENSDART00000183563
phosphorylase kinase, gamma 1a (muscle)
chr18_+_39067575 0.77 ENSDART00000077724
guanine nucleotide binding protein (G protein), beta 5b
chr19_-_47323267 0.77 ENSDART00000190077

chr23_+_29966466 0.75 ENSDART00000143583
dishevelled segment polarity protein 1a
chr2_+_45548890 0.75 ENSDART00000113994
fibronectin type III domain containing 7a
chr6_-_30839763 0.74 ENSDART00000154228
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr6_+_39506043 0.73 ENSDART00000086260

chr2_-_1548330 0.73 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr9_+_55379283 0.73 ENSDART00000192728
neuroligin 4b
chr2_+_42871831 0.73 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr25_+_3994823 0.72 ENSDART00000154020
EPS8 like 2
chr10_+_24468922 0.71 ENSDART00000008248
ENSDART00000183510
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_-_39005133 0.71 ENSDART00000104116
ENSDART00000151750
vitamin D receptor b
chr21_-_36571804 0.70 ENSDART00000138129
WW and C2 domain containing 1
chr6_+_13933464 0.70 ENSDART00000109144
protein tyrosine phosphatase, receptor type, Nb
chr19_+_31873308 0.69 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr18_-_5527050 0.68 ENSDART00000145400
ENSDART00000132498
ENSDART00000146209
zgc:153317
chr2_-_9059955 0.68 ENSDART00000022768
adenylate kinase 5
chr21_-_37661570 0.68 ENSDART00000174570
Nedd4 family interacting protein 1, like
chr19_-_42045372 0.68 ENSDART00000144275
trio Rho guanine nucleotide exchange factor a
chr1_+_6862917 0.68 ENSDART00000182953
erb-b2 receptor tyrosine kinase 4a
chr23_-_19103855 0.68 ENSDART00000016901
par-6 partitioning defective 6 homolog beta (C. elegans)
chr12_+_47698356 0.67 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr21_-_44081540 0.66 ENSDART00000130833

chr20_-_5291012 0.65 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr9_+_29643036 0.65 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr9_-_22355391 0.64 ENSDART00000009115
crystallin, gamma M3
chr25_+_7671640 0.64 ENSDART00000145367
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr5_-_6377865 0.64 ENSDART00000031775
zgc:73226
chr10_+_33902264 0.64 ENSDART00000193793
furry homolog b (Drosophila)
chr9_+_2574122 0.64 ENSDART00000166326
ENSDART00000191822
si:ch73-167c12.2
chr25_+_19149241 0.64 ENSDART00000184982
ENSDART00000067324
milk fat globule-EGF factor 8 protein b
chr16_+_9540033 0.63 ENSDART00000149574
carbonic anhydrase XIV
chr16_-_31622777 0.63 ENSDART00000137311
ENSDART00000002930
PHD finger protein 20 like 1
chr22_-_31060579 0.63 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr22_+_5176693 0.61 ENSDART00000160927
ceramide synthase 1
chr2_+_41926707 0.61 ENSDART00000023208
zgc:110183
chr25_-_25058508 0.61 ENSDART00000087570
ENSDART00000178891

chr18_-_48983690 0.60 ENSDART00000182359

chr1_-_22757145 0.60 ENSDART00000134719
prominin 1 b
chr3_-_42981739 0.58 ENSDART00000167844
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr21_+_5882300 0.58 ENSDART00000165065
ubiquinol-cytochrome c reductase, complex III subunit X
chr11_+_30663300 0.57 ENSDART00000161662
tau tubulin kinase 1a
chr23_-_18024543 0.57 ENSDART00000139695
peptidase M20 domain containing 1, tandem duplicate 1
chr7_-_66868543 0.56 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr24_-_31425799 0.56 ENSDART00000157998
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr4_+_22480169 0.55 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr7_+_69470442 0.54 ENSDART00000189593
GABA(A) receptor-associated protein b
chr20_-_43663494 0.54 ENSDART00000144564

chr1_+_44127292 0.54 ENSDART00000160542
calcium binding protein 2a
chr3_+_39922602 0.54 ENSDART00000193937
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr11_+_42474694 0.54 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr7_-_74057288 0.53 ENSDART00000189740

chr20_+_37457642 0.53 ENSDART00000132771
adhesion G protein-coupled receptor G6
chr25_-_27621268 0.53 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr20_+_32552912 0.53 ENSDART00000009691
Scm polycomb group protein like 4
chr21_-_4922981 0.53 ENSDART00000191819
ENSDART00000113556
ENSDART00000193269
ENSDART00000182961
potassium channel, subfamily T, member 1
chr1_-_55785722 0.53 ENSDART00000142069
ENSDART00000043933
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr17_+_23584268 0.52 ENSDART00000192675
solute carrier family 16, member 12a
chr11_+_40812590 0.52 ENSDART00000186690
ERBB receptor feedback inhibitor 1a
chr12_-_6818676 0.52 ENSDART00000106391
protocadherin-related 15b
chr1_-_9629705 0.52 ENSDART00000166601
ENSDART00000164079
UDP glucuronosyltransferase 5 family, polypeptide B5
chr23_+_41679586 0.52 ENSDART00000067662

chr24_-_33873451 0.51 ENSDART00000159840
acid-sensing (proton-gated) ion channel 1c
chr1_+_18811679 0.51 ENSDART00000078610
solute carrier family 25, member 51a
chr22_+_19366866 0.50 ENSDART00000137301
si:dkey-21e2.12
chr3_+_7808459 0.50 ENSDART00000162374
hook microtubule-tethering protein 2
chr1_-_9195629 0.50 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr22_-_14739491 0.50 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr25_+_31277415 0.50 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr15_+_34592215 0.50 ENSDART00000099776
tetraspanin 13a
chr7_+_13382852 0.50 ENSDART00000166318
diacylglycerol lipase, alpha
chr6_-_39649504 0.49 ENSDART00000179960
ENSDART00000190951
La ribonucleoprotein domain family, member 4Ab
chr1_-_17797802 0.48 ENSDART00000041215
sorbin and SH3 domain containing 2a
chr15_-_46779934 0.48 ENSDART00000085136
chloride channel 2c
chr7_-_50410524 0.48 ENSDART00000083346
huntingtin interacting protein K
chr22_+_5176255 0.48 ENSDART00000092647
ceramide synthase 1
chr11_-_45171139 0.47 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
synaptogyrin 2b
chr10_+_21867307 0.47 ENSDART00000126629
cerebellin 17
chr17_-_26604946 0.47 ENSDART00000087062
family with sequence similarity 149, member B1
chr2_-_4925025 0.46 ENSDART00000160257
discs, large (Drosophila) homolog 1, like
chr9_-_27442339 0.46 ENSDART00000138602
syntaxin binding protein 5-like
chr1_+_10221568 0.45 ENSDART00000152424
neuropeptide Y receptor Y2, like
chr18_+_16750080 0.45 ENSDART00000136320
ring finger protein 141
chr11_-_44543082 0.45 ENSDART00000099568
G protein-coupled receptor 137Bb
chr12_+_47044707 0.45 ENSDART00000186506
zinc finger, RAN-binding domain containing 1a
chr7_+_69459759 0.44 ENSDART00000160500
CTD nuclear envelope phosphatase 1b
chr4_+_76671012 0.44 ENSDART00000005585
membrane-spanning 4-domains, subfamily A, member 17a.2
chr5_-_71460556 0.44 ENSDART00000108804
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr11_-_8126223 0.43 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr18_+_21408794 0.43 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr12_-_18883079 0.43 ENSDART00000178619
shisa family member 8b
chr1_+_38858399 0.43 ENSDART00000165454

chr11_-_45141309 0.43 ENSDART00000181736
calcium activated nucleotidase 1b
chr11_+_2855430 0.42 ENSDART00000172837
kinesin family member 21B
chr23_+_41800052 0.42 ENSDART00000141484
prodynorphin
chr23_+_44741500 0.42 ENSDART00000166421
ATPase Na+/K+ transporting subunit beta 2a
chr17_+_389218 0.41 ENSDART00000162898
si:rp71-62i8.1
chr7_-_11596450 0.41 ENSDART00000173863
StAR-related lipid transfer (START) domain containing 5
chr23_+_11669109 0.41 ENSDART00000091416
contactin 3a, tandem duplicate 1
chr24_-_26328721 0.41 ENSDART00000125468
apolipoprotein Db
chr11_+_3005536 0.41 ENSDART00000174539
copine Vb
chr21_-_25685739 0.41 ENSDART00000129619
ENSDART00000101205
phosphorylase kinase, gamma 1b (muscle)
chr9_+_11202552 0.41 ENSDART00000151931
acid-sensing (proton-gated) ion channel family member 4a
chr7_+_73488035 0.41 ENSDART00000110330
Rho guanine nucleotide exchange factor (GEF) 40
chr9_-_48397702 0.40 ENSDART00000147169
zgc:172182
chr23_-_900795 0.40 ENSDART00000190517
ENSDART00000182849
ENSDART00000111456
ENSDART00000185430
RNA binding motif protein 10
chr11_-_42554290 0.40 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr25_+_35913614 0.40 ENSDART00000022437
glucose-6-phosphate isomerase a
chr2_-_10014821 0.40 ENSDART00000185525

chr23_-_42752550 0.40 ENSDART00000187059
si:ch73-217n20.1
chr13_+_733027 0.40 ENSDART00000149547
neurexin 1b
chr8_+_20679759 0.40 ENSDART00000088668
nuclear factor I/C
chr13_-_31397987 0.39 ENSDART00000008287
phosphoglycerate mutase 1a
chr23_+_45200481 0.39 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
PC4 and SFRS1 interacting protein 1b
chr1_-_25144439 0.38 ENSDART00000132355
F-box and WD repeat domain containing 7
chr8_+_36560019 0.38 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
splicing factor 3a, subunit 1
chr17_-_43391499 0.38 ENSDART00000189280
inositol-tetrakisphosphate 1-kinase b
chr3_+_40170216 0.38 ENSDART00000011568
synaptogyrin 3a
chr5_+_35458346 0.38 ENSDART00000141239
ER lipid raft associated 2
chr21_-_22709251 0.38 ENSDART00000140032
si:dkeyp-69c1.9
chr25_-_21816269 0.38 ENSDART00000152014
zgc:158222
chr21_+_18997511 0.37 ENSDART00000145591
ribosomal protein L17
chr3_-_34084387 0.37 ENSDART00000155365
immunoglobulin heavy variable 4-3
chr15_+_11427620 0.37 ENSDART00000168688
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr5_+_45140914 0.37 ENSDART00000172702
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_2223837 0.36 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr16_-_28856112 0.36 ENSDART00000078543
synaptotagmin XIb
chr20_-_44557037 0.35 ENSDART00000140995
major facilitator superfamily domain containing 2B

Network of associatons between targets according to the STRING database.

First level regulatory network of emx2+emx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.6 1.7 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.5 1.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.4 2.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 1.4 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.3 0.8 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.3 0.8 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 0.8 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.2 1.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.8 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 2.2 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 2.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.6 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 1.0 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.7 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 1.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.5 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.8 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.8 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.3 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.7 GO:0032475 otolith formation(GO:0032475)
0.1 1.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.2 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 2.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 1.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 10.7 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.0 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 1.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 1.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.2 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 1.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 1.3 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.8 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.3 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.7 GO:0060119 inner ear receptor cell development(GO:0060119)
0.0 0.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.3 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.2 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.3 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0007602 phototransduction(GO:0007602)
0.0 1.5 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 1.0 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.3 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.5 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.6 GO:0007338 single fertilization(GO:0007338)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.5 GO:0045095 keratin filament(GO:0045095)
0.1 1.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.1 1.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 4.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0071914 prominosome(GO:0071914)
0.1 1.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.4 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 2.6 GO:0043679 axon terminus(GO:0043679)
0.1 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0016460 myosin II complex(GO:0016460)
0.1 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.3 1.7 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 2.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.8 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 1.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.2 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 1.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 1.0 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 0.2 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 4.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 2.2 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 2.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.1 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 5.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.7 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.7 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.3 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors