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PRJEB1986: zebrafish developmental stages transcriptome

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Results for elf3

Z-value: 0.71

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Transcription factors associated with elf3

Gene Symbol Gene ID Gene Info
ENSDARG00000077982 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf3dr11_v1_chr22_+_661711_661711-0.233.3e-01Click!

Activity profile of elf3 motif

Sorted Z-values of elf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_69482891 1.46 ENSDART00000109487

chr17_-_6730247 1.43 ENSDART00000031091
visinin-like 1b
chr5_-_21524251 1.37 ENSDART00000176793
ENSDART00000040184
teneurin transmembrane protein 1
chr19_-_40192249 1.25 ENSDART00000051972
granulin 1
chr6_-_10233538 1.18 ENSDART00000182004
ENSDART00000149237
ENSDART00000148876
xin actin binding repeat containing 2a
chr12_-_14551077 1.18 ENSDART00000188717

chr24_-_11127493 1.18 ENSDART00000144066
myosin VIIA and Rab interacting protein
chr13_-_37210369 1.10 ENSDART00000140744
si:dkeyp-77c8.4
chr24_-_38113208 1.08 ENSDART00000079003
c-reactive protein, pentraxin-related
chr11_-_141592 1.04 ENSDART00000092787
cyclin-dependent kinase 4
chr22_-_31517300 0.97 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr16_+_34528409 0.96 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr7_+_35075847 0.94 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr13_+_30055171 0.92 ENSDART00000143581
ENSDART00000132027
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr6_-_17849786 0.92 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr16_+_14033121 0.92 ENSDART00000135844
RUN and SH3 domain containing 1
chr14_+_26796917 0.90 ENSDART00000137695
kelch-like family member 4
chr20_-_2090789 0.89 ENSDART00000113237
Rho GTPase activating protein 18
chr8_+_53423408 0.87 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr7_+_73295890 0.85 ENSDART00000174331
ENSDART00000174250

chr10_+_3507861 0.84 ENSDART00000092684
rabphilin 3A homolog (mouse), a
chr19_+_48176745 0.82 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr13_+_30054996 0.81 ENSDART00000110061
ENSDART00000186045
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_2101541 0.81 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
muscleblind-like splicing regulator 2
chr3_-_5228137 0.80 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr10_-_22828302 0.77 ENSDART00000079459
ENSDART00000100468
period circadian clock 1a
chr5_+_52067723 0.77 ENSDART00000166902
SET binding protein 1
chr12_-_7824291 0.76 ENSDART00000148673
ENSDART00000149453
ankyrin 3b
chr5_+_67812062 0.74 ENSDART00000158611
zgc:175280
chr10_-_41450367 0.74 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr3_+_19460991 0.72 ENSDART00000169124
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a
chr2_-_24068848 0.71 ENSDART00000145526
solute carrier family 12 (potassium/chloride transporter), member 7a
chr1_-_24349759 0.70 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr10_+_2568793 0.70 ENSDART00000191985
ENSDART00000081922
spindlin a
chr23_-_1587955 0.68 ENSDART00000136037
fibronectin type III domain containing 7b
chr1_+_157793 0.67 ENSDART00000152205
cullin 4A
chr23_+_1181248 0.64 ENSDART00000170942
utrophin
chr9_-_22339582 0.63 ENSDART00000134805
crystallin, gamma M2d1
chr1_-_47071979 0.61 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr4_-_9533345 0.61 ENSDART00000128501
si:ch73-139j3.4
chr23_+_27068225 0.59 ENSDART00000054238
major intrinsic protein of lens fiber a
chr15_+_3808996 0.59 ENSDART00000110227
ring finger protein 14
chr17_-_11418513 0.58 ENSDART00000064412
ENSDART00000151847
AT rich interactive domain 4A (RBP1-like)
chr17_+_3993772 0.58 ENSDART00000170822
ENSDART00000168613
ENSDART00000186174
thioredoxin-related transmembrane protein 4
chr10_+_1668106 0.58 ENSDART00000142278
small G protein signaling modulator 1b
chr20_-_33462961 0.57 ENSDART00000135927
si:dkey-65b13.1
chr2_+_9061885 0.56 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr17_+_13664442 0.56 ENSDART00000171689
leucine rich repeat and fibronectin type III domain containing 5a
chr9_+_6079528 0.55 ENSDART00000142167
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr15_+_16525126 0.55 ENSDART00000193455
polypeptide N-acetylgalactosaminyltransferase 17
chr7_+_60161002 0.54 ENSDART00000054007
solute carrier family 8 (sodium/calcium exchanger), member 4b
chr3_-_5228841 0.54 ENSDART00000092373
ENSDART00000182438
myosin, heavy chain 9b, non-muscle
chr10_-_105100 0.53 ENSDART00000145716
tetratricopeptide repeat domain 3
chr13_+_4225173 0.52 ENSDART00000058242
ENSDART00000143456
male-enhanced antigen 1
chr23_+_42304602 0.52 ENSDART00000166004
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr7_-_6592142 0.52 ENSDART00000160137
potassium inwardly-rectifying channel, subfamily J, member 10a
chr22_-_16403602 0.52 ENSDART00000183417
laminin, alpha 3
chr15_-_20180475 0.52 ENSDART00000048183
exocyst complex component 3-like 2b
chr13_-_2189761 0.51 ENSDART00000166255
muscular LMNA-interacting protein
chr6_-_55254786 0.51 ENSDART00000113805
nuclear factor of activated T cells 2b
chr1_+_532766 0.51 ENSDART00000179731
ENSDART00000060944
mitochondrial ribosomal protein L39
chr6_+_3282809 0.51 ENSDART00000187444
ENSDART00000187407
ENSDART00000191883
lysine (K)-specific demethylase 4A, genome duplicate a
chr8_+_50742975 0.50 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
chr22_-_23781083 0.50 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
complement factor H like 3
chr2_+_33382648 0.50 ENSDART00000137207
ENSDART00000098831
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_61995745 0.50 ENSDART00000171539

chr17_-_21993620 0.49 ENSDART00000179905
ENSDART00000078873
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 3
chr2_-_55779927 0.49 ENSDART00000168579

chr17_+_25290136 0.48 ENSDART00000173295
kelch repeat and BTB (POZ) domain containing 11
chr20_+_42761881 0.48 ENSDART00000113625
Pim proto-oncogene, serine/threonine kinase, related 113
chr3_+_46479913 0.48 ENSDART00000149755
tyrosine kinase 2
chr1_-_37383741 0.48 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr17_-_5610514 0.47 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr19_-_36234185 0.47 ENSDART00000186003
CUB and Sushi multiple domains 2
chr17_+_27134806 0.47 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr12_+_43585527 0.46 ENSDART00000161590
clarin 3
chr21_+_5888641 0.46 ENSDART00000091331
proline dehydrogenase (oxidase) 1a
chr23_-_874418 0.46 ENSDART00000133906
RNA binding motif protein 10
chr5_+_42467867 0.46 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr7_+_65261354 0.45 ENSDART00000168388
beta-carotene oxygenase 1
chr7_+_65261576 0.45 ENSDART00000169566
beta-carotene oxygenase 1
chr4_-_14926637 0.45 ENSDART00000110199
PR domain containing 4
chr3_+_24459709 0.45 ENSDART00000180976
chromobox homolog 6b
chr16_+_46807214 0.45 ENSDART00000185524

chr4_+_26629368 0.45 ENSDART00000183575
IQ motif and Sec7 domain 3a
chr3_+_29942338 0.44 ENSDART00000158220
interferon-induced protein 35
chr4_+_2655358 0.44 ENSDART00000007638
B cell receptor associated protein 29
chr9_+_12948511 0.44 ENSDART00000135797
si:dkey-230p4.1
chr10_+_10636237 0.44 ENSDART00000136853
family with sequence similarity 163, member B
chr3_-_32902138 0.44 ENSDART00000144026
ENSDART00000083874
ENSDART00000145443
ENSDART00000148239
ENSDART00000134917
K(lysine) acetyltransferase 7a
chr24_+_39990695 0.44 ENSDART00000040281

chr20_-_51727860 0.43 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr10_+_21576909 0.43 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr24_-_1985007 0.43 ENSDART00000189870
par-3 family cell polarity regulator
chr19_+_1003332 0.43 ENSDART00000081779
zinc finger, DHHC-type containing 3b
chr16_-_16590489 0.42 ENSDART00000190021
si:ch211-257p13.3
chr16_-_22251414 0.42 ENSDART00000158500
ENSDART00000179998
ATPase phospholipid transporting 8B2
chr23_-_44233408 0.42 ENSDART00000149318
ENSDART00000085528
zgc:158659
chr19_-_40199081 0.41 ENSDART00000051970
ENSDART00000151079
granulin 2
chr15_-_8856391 0.41 ENSDART00000008273
RAB4B, member RAS oncogene family
chr1_-_55008882 0.41 ENSDART00000083572
zgc:136864
chr14_-_1949277 0.40 ENSDART00000159435
protocadherin 2 gamma 5
chr4_-_17263210 0.40 ENSDART00000147853
lymphoid-restricted membrane protein
chr22_-_16377666 0.40 ENSDART00000161878
tetratricopeptide repeat domain 39C
chr16_+_1802307 0.40 ENSDART00000180026
glutamate ionotropic receptor kainate type subunit 2
chr1_-_59407322 0.40 ENSDART00000161661
si:ch211-188p14.5
chr11_-_43104475 0.40 ENSDART00000125368
acylphosphatase 2, muscle type
chr6_-_52796212 0.40 ENSDART00000154133
recombination signal binding protein for immunoglobulin kappa J region-like
chr15_+_9327252 0.40 ENSDART00000144381
sarcoglycan, gamma
chr17_-_44440832 0.39 ENSDART00000148786
exocyst complex component 5
chr20_-_1191910 0.38 ENSDART00000043218
ubiquitin-conjugating enzyme E2, J1
chr24_-_35707552 0.38 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr23_-_19103855 0.38 ENSDART00000016901
par-6 partitioning defective 6 homolog beta (C. elegans)
chr13_+_27316632 0.38 ENSDART00000016121
eukaryotic translation elongation factor 1 alpha 1a
chr9_-_4598883 0.37 ENSDART00000171927
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr5_-_41124241 0.37 ENSDART00000083561
myotubularin related protein 12
chr23_+_17981127 0.37 ENSDART00000012571
ENSDART00000145200
chitinase, acidic.6
chr20_+_2139436 0.37 ENSDART00000155311
l(3)mbt-like 3 (Drosophila)
chr4_+_4902392 0.37 ENSDART00000133866
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr6_-_55354004 0.37 ENSDART00000165911
PDX1 C-terminal inhibiting factor 1
chr18_-_26894732 0.37 ENSDART00000147735
ENSDART00000188938

si:dkey-24l11.2
chr12_-_44043285 0.36 ENSDART00000163074
si:ch211-182p11.1
chr15_-_568645 0.36 ENSDART00000156744
cerebellin 18
chr3_-_11972516 0.36 ENSDART00000140123
heme oxygenase 2b
chr3_+_57997980 0.36 ENSDART00000168477
ENSDART00000193840
pyrroline-5-carboxylate reductase 1a
chr12_+_33395748 0.35 ENSDART00000129458
fatty acid synthase
chr1_-_44314 0.35 ENSDART00000160050
transmembrane protein 39A
chr4_-_37766174 0.35 ENSDART00000170066
si:dkey-207l24.2
chr25_-_34979548 0.35 ENSDART00000153904
si:dkey-108k21.7
chr5_-_13206878 0.34 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr7_-_51476276 0.34 ENSDART00000082464
NHS-like 2
chr22_+_1586060 0.34 ENSDART00000160793
si:ch211-255f4.11
chr1_+_12301913 0.34 ENSDART00000165733
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr3_+_36366053 0.34 ENSDART00000181140
regulator of G protein signaling 9a
chr21_+_40443118 0.34 ENSDART00000190675
slingshot protein phosphatase 2b
chr19_+_42694211 0.33 ENSDART00000180153
cytoplasmic linker associated protein 2
chr2_-_32769759 0.33 ENSDART00000178951
beaded filament structural protein 2, phakinin
chr14_-_11529311 0.33 ENSDART00000127208
si:ch211-153b23.7
chr3_+_431208 0.33 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
chr20_+_32481348 0.33 ENSDART00000185018
osteopetrosis associated transmembrane protein 1
chr15_-_8856785 0.33 ENSDART00000192816
RAB4B, member RAS oncogene family
chr20_+_43602810 0.32 ENSDART00000142543
si:dkey-206f10.1
chr14_-_2327825 0.32 ENSDART00000180328
ENSDART00000191135
ENSDART00000114302
ENSDART00000189869
protocadherin 2 alpha b 8
protocadherin 2 alpha a 1
chr6_-_12459412 0.32 ENSDART00000090266
ENSDART00000144028
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr25_-_35664817 0.32 ENSDART00000148718
leucine-rich repeat kinase 2
chr1_+_40237276 0.32 ENSDART00000037553
fatty acid amide hydrolase 2a
chr22_-_3595439 0.32 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr11_+_38280454 0.32 ENSDART00000171496
si:dkey-166c18.1
chr23_+_19790962 0.32 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr20_+_42780162 0.32 ENSDART00000127069
Pim proto-oncogene, serine/threonine kinase, related 213
chr19_-_3759142 0.32 ENSDART00000170431
bloodthirsty-related gene family, member 21
chr13_-_5978433 0.31 ENSDART00000102555
ARP2 actin related protein 2b homolog
chr7_+_19762595 0.31 ENSDART00000130347
si:dkey-9k7.3
chr3_-_30625219 0.31 ENSDART00000151698
synaptotagmin III
chr22_+_26600834 0.30 ENSDART00000157411
adenylate cyclase 9
chr12_-_33859950 0.30 ENSDART00000131181
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr18_-_42333428 0.30 ENSDART00000034225
contactin 5
chr21_+_25801345 0.30 ENSDART00000035062
neurofibromin 2b (merlin)
chr1_+_36722122 0.29 ENSDART00000111566
transmembrane protein 184C
chr25_-_32311048 0.29 ENSDART00000181806
ENSDART00000086334

chr6_-_15065376 0.29 ENSDART00000087797
transforming growth factor, beta receptor associated protein 1
chr23_+_17980875 0.29 ENSDART00000163452
chitinase, acidic.6
chr2_+_31492662 0.29 ENSDART00000123495
calcium channel, voltage-dependent, beta 2b
chr9_+_24125445 0.28 ENSDART00000090346
post-GPI attachment to proteins 1
chr7_+_9922607 0.28 ENSDART00000184532
ENSDART00000113396
ceramide synthase 3a
chr15_-_35101143 0.28 ENSDART00000178430
ENSDART00000109593
biogenesis of lysosomal organelles complex-1, subunit 3
chr8_+_8712446 0.27 ENSDART00000158674
ELK1, member of ETS oncogene family
chr4_-_73311831 0.27 ENSDART00000174391
zgc:171727
chr7_+_41748693 0.27 ENSDART00000174379
ENSDART00000052168
histamine receptor H3
chr18_-_6982499 0.27 ENSDART00000101525
si:dkey-266m15.6
chr24_+_15670013 0.27 ENSDART00000185826

chr21_+_9576176 0.27 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr3_+_52737565 0.26 ENSDART00000108639
GEM interacting protein
chr3_-_34337969 0.26 ENSDART00000151634
trinucleotide repeat containing 6C1
chr9_-_54304684 0.26 ENSDART00000109512
interleukin 13
chr2_+_25929619 0.26 ENSDART00000137746
solute carrier family 7, member 14a
chr11_-_21304452 0.25 ENSDART00000163008
si:dkey-85p17.3
chr5_+_37487687 0.25 ENSDART00000184659

chr12_+_4573696 0.25 ENSDART00000152534
si:dkey-94f20.4
chr5_-_57311037 0.24 ENSDART00000149855
fer (fps/fes related) tyrosine kinase
chr22_+_569565 0.24 ENSDART00000037069
ubiquitin specific peptidase 49
chr20_+_39250673 0.24 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr22_-_16758438 0.24 ENSDART00000132829
PATJ, crumbs cell polarity complex component
chr13_-_24794486 0.24 ENSDART00000136177
STE20-like kinase a
chr6_+_51779863 0.24 ENSDART00000108534
transmembrane protein 74B
chr2_-_37462462 0.24 ENSDART00000145896
si:dkey-57k2.7
chr6_+_40714811 0.24 ENSDART00000153868
coiled-coil domain containing 36
chr23_-_37835794 0.24 ENSDART00000137358
CD40 molecule, TNF receptor superfamily member 5
chr6_-_442163 0.23 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr25_+_10947743 0.23 ENSDART00000073381
major histocompatibility complex class I LFA
chr15_-_2010926 0.23 ENSDART00000155688
dedicator of cytokinesis 10
chr8_+_22438398 0.23 ENSDART00000135145
zgc:153759
chr15_-_36352983 0.23 ENSDART00000059786
si:dkey-23k10.5
chr21_+_3941758 0.23 ENSDART00000181345
senataxin
chr19_+_25476228 0.22 ENSDART00000112808
collagen, type XXVIII, alpha 1a
chr11_-_34166960 0.22 ENSDART00000181571
ATPase 13A3
chr5_-_37252111 0.22 ENSDART00000185110
leucine-rich repeats and calponin homology (CH) domain containing 2
chr13_-_21701323 0.22 ENSDART00000164112
si:dkey-191g9.7
chr14_-_34276574 0.22 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr1_+_30103297 0.22 ENSDART00000146783
vacuolar protein sorting 8 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of elf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.7 GO:0097638 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.5 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.9 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0045830 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.5 GO:0036268 swimming(GO:0036268)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 0.5 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 0.5 GO:0006833 water transport(GO:0006833)
0.1 0.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.5 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.4 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.8 GO:0043153 response to hydrogen peroxide(GO:0042542) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.6 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.0 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.9 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.0 GO:2000108 regulation of platelet activation(GO:0010543) regulation of platelet aggregation(GO:0090330) positive regulation of leukocyte apoptotic process(GO:2000108)
0.0 0.2 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 1.2 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.5 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.3 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0030897 HOPS complex(GO:0030897)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.9 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.1 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.5 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.7 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization