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PRJEB1986: zebrafish developmental stages transcriptome

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Results for elf2a+elf2b

Z-value: 2.82

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Transcription factors associated with elf2a+elf2b

Gene Symbol Gene ID Gene Info
ENSDARG00000019459 E74-like factor 2a (ets domain transcription factor)
ENSDARG00000079626 E74-like factor 2b (ets domain transcription factor)
ENSDARG00000117064 E74-like factor 2b (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf2bdr11_v1_chr1_-_13964284_139642840.892.7e-07Click!
elf2adr11_v1_chr14_-_46070802_460708020.445.7e-02Click!

Activity profile of elf2a+elf2b motif

Sorted Z-values of elf2a+elf2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_26482096 12.71 ENSDART00000187280
SMAD family member 5
chr23_-_21471022 7.91 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr8_-_36554675 6.85 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr13_+_15941850 6.66 ENSDART00000016294
fidgetin-like 1
chr4_+_12031958 6.62 ENSDART00000044154
troponin T2c, cardiac
chr15_+_24737599 5.53 ENSDART00000078024
v-crk avian sarcoma virus CT10 oncogene homolog
chr25_+_186583 5.22 ENSDART00000161504
PCNA clamp associated factor
chr19_-_47782916 5.08 ENSDART00000063337
cell division cycle associated 8
chr1_+_25650917 4.88 ENSDART00000054235
pleiotropic regulator 1
chr23_-_13840433 4.87 ENSDART00000104831
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr2_+_19163965 4.80 ENSDART00000166073
ELOVL fatty acid elongase 1a
chr5_-_66028371 4.77 ENSDART00000183012
NOTCH regulated ankyrin repeat protein b
chr19_-_47782586 4.73 ENSDART00000177126
cell division cycle associated 8
chr16_+_20294976 4.71 ENSDART00000059619
FK506 binding protein 14
chr20_-_2619316 4.57 ENSDART00000185777
BUB1 mitotic checkpoint serine/threonine kinase
chr25_+_17405201 4.55 ENSDART00000164349
E2F transcription factor 4
chr5_-_67365750 4.53 ENSDART00000062359
uracil DNA glycosylase a
chr21_-_4793686 4.49 ENSDART00000158232
notch 1a
chr25_+_17405458 4.48 ENSDART00000186711
E2F transcription factor 4
chr11_-_306533 4.35 ENSDART00000173437
POC1 centriolar protein A
chr25_-_19574146 4.27 ENSDART00000156811
si:ch211-59o9.10
chr5_-_66028714 4.23 ENSDART00000022625
ENSDART00000164228
NOTCH regulated ankyrin repeat protein b
chr2_+_6243144 4.19 ENSDART00000058258
guanine nucleotide binding protein (G protein), gamma 5
chr9_+_2041535 4.14 ENSDART00000093187
limb and neural patterns a
chr9_+_426392 4.14 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr1_+_54737353 4.12 ENSDART00000130675
ENSDART00000162075
phosphatidylinositol 4-kinase type 2 alpha
chr19_+_43359075 4.01 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
Yes-related kinase
chr20_-_4157138 3.96 ENSDART00000112999
zgc:194224
chr8_-_41228530 3.93 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr20_+_13141408 3.89 ENSDART00000034098
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr8_-_51753604 3.89 ENSDART00000007090
T-box 16
chr4_+_13931578 3.86 ENSDART00000142466
periphilin 1
chr6_+_3816241 3.84 ENSDART00000178545
glutamate-rich 2
chr18_-_40884087 3.83 ENSDART00000059194
small nuclear ribonucleoprotein D2 polypeptide
chr16_+_52966812 3.77 ENSDART00000148435
ENSDART00000049099
ENSDART00000150117
thyroid hormone receptor interactor 13
chr17_+_43013171 3.69 ENSDART00000055541
gsk3b interacting protein
chr21_+_8341774 3.65 ENSDART00000129749
ENSDART00000055325
ENSDART00000133804
proteasome subunit beta 7
chr5_+_36895860 3.60 ENSDART00000134493
serine/arginine-rich splicing factor 7a
chr1_+_29140884 3.56 ENSDART00000053926
ENSDART00000150133
ankyrin repeat domain 10a
chr7_+_71764883 3.56 ENSDART00000166865
myosin, light chain 12, genome duplicate 1
chr7_+_59169081 3.56 ENSDART00000167980
oligosaccharyltransferase complex subunit
chr12_-_28910419 3.55 ENSDART00000153278
ENSDART00000152937
si:ch73-81k8.2
chr11_-_36350876 3.50 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr15_-_28802140 3.48 ENSDART00000156120
ENSDART00000156708
ENSDART00000122536
ENSDART00000155008
ENSDART00000153825
CD3e molecule, epsilon associated protein
chr25_-_3347418 3.48 ENSDART00000082385
golgi transport 1Bb
chr11_-_23219367 3.46 ENSDART00000003646
opticin
chr9_-_1986014 3.44 ENSDART00000142842
homeobox D12a
chr19_-_42607451 3.43 ENSDART00000004392
FK506 binding protein 9
chr25_-_19608382 3.42 ENSDART00000022279
ENSDART00000135201
ENSDART00000147223
ENSDART00000190220
ENSDART00000184242
ENSDART00000166824
G-2 and S-phase expressed 1
chr7_-_21887104 3.42 ENSDART00000019699
methyltransferase like 3
chr18_+_29898955 3.42 ENSDART00000064080
centromere protein N
chr2_+_20967673 3.36 ENSDART00000057174
actin related protein 2/3 complex, subunit 5A
chr2_+_38225427 3.34 ENSDART00000141614
si:ch211-14a17.11
chr20_-_22484621 3.33 ENSDART00000063601
GS homeobox 2
chr23_-_27589508 3.28 ENSDART00000178404
si:ch211-156j22.4
chr19_+_9459050 3.27 ENSDART00000186419
si:ch211-288g17.3
chr5_-_67365006 3.24 ENSDART00000136116
uracil DNA glycosylase a
chr12_+_27462225 3.24 ENSDART00000105661
mesenchyme homeobox 1
chr12_-_33789006 3.23 ENSDART00000034550
lethal giant larvae homolog 2 (Drosophila)
chr23_+_21459263 3.21 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr11_-_18107447 3.20 ENSDART00000187376
glutamine-rich 1
chr20_-_38827623 3.20 ENSDART00000153310
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_-_67180800 3.17 ENSDART00000065264
cell division cycle associated 5
chr10_-_3332362 3.16 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr15_-_5624361 3.15 ENSDART00000176446
ENSDART00000114410
WD repeat domain 62
chr1_-_31657854 3.15 ENSDART00000085309
deleted in primary ciliary dyskinesia homolog (mouse)
chr12_-_34435604 3.15 ENSDART00000115088
baculoviral IAP repeat containing 5a
chr20_-_54198130 3.14 ENSDART00000160409
ADP-ribosylation factor 6a
chr5_+_69733096 3.13 ENSDART00000169013
ADP-ribosylation factor-like 6 interacting protein 4
chr1_-_21881818 3.12 ENSDART00000047728
maternal embryonic leucine zipper kinase
chr10_+_44363195 3.11 ENSDART00000161744
lysine methyltransferase 5Aa
chr8_+_26059677 3.09 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr2_-_34138064 3.09 ENSDART00000133381
centromere protein L
chr7_+_32693890 3.09 ENSDART00000121972
solute carrier family 39 (zinc transporter), member 13
chr2_+_9973687 3.06 ENSDART00000043499
SEC22 homolog B, vesicle trafficking protein a
chr18_-_3552414 3.06 ENSDART00000163762
ENSDART00000165434
ENSDART00000161197
ENSDART00000166841
ENSDART00000170260
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr7_+_19552381 3.05 ENSDART00000169060
si:ch211-212k18.5
chr16_-_25380903 3.04 ENSDART00000086375
ENSDART00000188587
ADNP homeobox 2a
chr14_-_14687004 3.01 ENSDART00000169970
germ cell nuclear acidic peptidase
chr11_-_41084358 3.01 ENSDART00000166999
zgc:175088
chr8_+_36554816 3.01 ENSDART00000126687
splicing factor 3a, subunit 1
chr18_+_41527877 3.00 ENSDART00000146972
selenoprotein T, 1b
chr13_+_15933168 3.00 ENSDART00000131390
fidgetin-like 1
chr17_-_42218652 2.99 ENSDART00000081396
ENSDART00000190007
NK2 homeobox 2a
chr7_+_22981909 2.98 ENSDART00000122449
cyclin B3
chr11_-_36350421 2.95 ENSDART00000141477
proteasome subunit alpha 5
chr11_+_8129536 2.94 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr13_+_33651416 2.94 ENSDART00000180221

chr7_+_54651109 2.93 ENSDART00000169987
oral cancer overexpressed 1
chr16_+_11818126 2.92 ENSDART00000145727
chemokine (C-X-C motif) receptor 3, tandem duplicate 2
chr12_+_27232173 2.92 ENSDART00000193714
transmembrane protein 106A
chr17_-_28811747 2.92 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase
chr13_+_41917606 2.91 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr11_-_36263886 2.91 ENSDART00000140397
nuclear transcription factor Y, alpha
chr4_+_9592486 2.90 ENSDART00000080829
heat shock protein 14
chr21_+_17016337 2.89 ENSDART00000065755
GPN-loop GTPase 3
chr17_+_44441042 2.88 ENSDART00000142123
adaptor-related protein complex 5, mu 1 subunit
chr2_-_34138400 2.88 ENSDART00000056667
centromere protein L
chr13_+_24402406 2.87 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr6_+_40775800 2.87 ENSDART00000085090
si:ch211-157b11.8
chr2_+_30249977 2.84 ENSDART00000109160
ENSDART00000135171
transmembrane protein 70
chr13_-_35459928 2.84 ENSDART00000144109
SLX4 interacting protein
chr5_+_28497956 2.83 ENSDART00000191935
notochord formation related
chr3_+_31058464 2.83 ENSDART00000153381
si:dkey-66i24.7
chr7_-_24994568 2.82 ENSDART00000002961
REST corepressor 2
chr9_+_48819280 2.82 ENSDART00000112555
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr22_-_10641873 2.81 ENSDART00000064772
cytochrome b561 family, member D2
chr7_-_32021853 2.81 ENSDART00000134521
kinesin family member 18A
chr1_+_54013457 2.80 ENSDART00000012104
ENSDART00000126339
deltaA
chr23_-_7052362 2.78 ENSDART00000127702
ENSDART00000192468
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr14_-_31618243 2.77 ENSDART00000016592
membrane magnesium transporter 1
chr11_-_18017918 2.77 ENSDART00000040171
glutamine-rich 1
chr13_-_33700461 2.77 ENSDART00000160520
MAD2L1 binding protein
chr6_+_14949950 2.77 ENSDART00000149202
ENSDART00000149949
POU class 3 homeobox 3b
chr21_-_30408775 2.77 ENSDART00000101037
NHP2 ribonucleoprotein homolog (yeast)
chr3_-_27065477 2.76 ENSDART00000185660
activating transcription factor 7 interacting protein 2
chr14_+_15768942 2.75 ENSDART00000158998
endoplasmic reticulum-golgi intermediate compartment 1
chr4_-_22363709 2.74 ENSDART00000037670
origin recognition complex, subunit 5
chr2_-_15040345 2.74 ENSDART00000109657
si:dkey-10f21.4
chr23_-_21463788 2.73 ENSDART00000079265
hairy-related 4, tandem duplicate 4
chr19_-_32518556 2.71 ENSDART00000103410
zinc finger and BTB domain containing 8B
chr24_-_9291857 2.69 ENSDART00000149875
TGFB-induced factor homeobox 1
chr5_-_51998708 2.69 ENSDART00000097194
serine incorporator 5
chr6_+_18544791 2.69 ENSDART00000167463
ENSDART00000169599
ATPase family, AAA domain containing 5b
chr21_-_25601648 2.68 ENSDART00000042578
EGF containing fibulin extracellular matrix protein 2b
chr1_+_38142354 2.68 ENSDART00000179352
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr7_+_50395856 2.67 ENSDART00000032324
HD domain containing 3
chr6_+_33931740 2.67 ENSDART00000130492
ENSDART00000151213
origin recognition complex, subunit 1
chr18_+_49248389 2.66 ENSDART00000059285
ENSDART00000142004
ENSDART00000132751
Yip1 interacting factor homolog B (S. cerevisiae)
chr2_+_26288301 2.66 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr1_-_21723329 2.65 ENSDART00000137138
si:ch211-134c9.2
chr18_-_26797723 2.65 ENSDART00000008013
SEC11 homolog A, signal peptidase complex subunit
chr3_-_49382896 2.64 ENSDART00000169115
si:ch73-167f10.1
chr14_-_22015232 2.63 ENSDART00000137795
structure specific recognition protein 1a
chr18_-_8378251 2.63 ENSDART00000192807
selenophosphate synthetase 1
chr13_-_31296358 2.63 ENSDART00000030946
PR domain containing 8
chr20_-_33497128 2.61 ENSDART00000101974
enhancer of rudimentary homolog (Drosophila)
chr7_-_30926030 2.61 ENSDART00000075421
sorbitol dehydrogenase
chr6_-_8392104 2.60 ENSDART00000081561
ENSDART00000181178
interleukin enhancer binding factor 3a
chr5_-_54714525 2.60 ENSDART00000150138
ENSDART00000150070
cyclin B1
chr17_-_24890843 2.59 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
UDP-galactose-4-epimerase
chr14_+_20911310 2.59 ENSDART00000160318
lysozyme g-like 2
chr16_-_54498109 2.58 ENSDART00000083713
CDC-like kinase 2b
chr11_-_16115804 2.57 ENSDART00000143436
ENSDART00000157928
ribosome production factor 1 homolog
chr2_+_38055529 2.57 ENSDART00000145642
si:rp71-1g18.1
chr16_-_11778933 2.56 ENSDART00000184916
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
chr9_+_20853894 2.56 ENSDART00000003648
WD repeat domain 3
chr24_-_6024466 2.56 ENSDART00000040865
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr20_+_19066858 2.55 ENSDART00000192086
SRY (sex determining region Y)-box 7
chr5_+_51833132 2.54 ENSDART00000167491
PAP associated domain containing 4
chr16_+_43139504 2.54 ENSDART00000065643
DBF4 zinc finger
chr18_+_49969568 2.54 ENSDART00000126916
MOB kinase activator 2b
chr4_+_5506952 2.53 ENSDART00000032857
ENSDART00000160222
mitogen-activated protein kinase 11
chr25_+_3549401 2.53 ENSDART00000166312
coiled-coil domain containing 77
chr21_+_723998 2.51 ENSDART00000160956
ornithine decarboxylase antizyme 1b
chr22_-_26353916 2.51 ENSDART00000077958
calpain 2, (m/II) large subunit b
chr1_-_34447515 2.50 ENSDART00000143048
LIM domain 7b
chr10_+_15970 2.50 ENSDART00000040240
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr7_+_22982201 2.50 ENSDART00000134116
cyclin B3
chr4_-_72295710 2.48 ENSDART00000182983
si:cabz01071911.3
chr6_-_39313027 2.48 ENSDART00000012644
keratin 4
chr16_+_11779534 2.47 ENSDART00000133497
si:dkey-250k15.4
chr21_+_28749720 2.47 ENSDART00000145178
zgc:100829
chr5_-_67365333 2.47 ENSDART00000133438
uracil DNA glycosylase a
chr19_-_29853402 2.47 ENSDART00000024292
ENSDART00000188508
taxilin alpha
chr19_-_34089205 2.47 ENSDART00000163618
ENSDART00000161666
RP9, pre-mRNA splicing factor
chr16_+_33144306 2.46 ENSDART00000101953
rhomboid, veinlet-like 2 (Drosophila)
chr3_-_24681404 2.46 ENSDART00000161612

chr21_-_226071 2.46 ENSDART00000160667
nucleoporin 54
chr6_-_48347724 2.45 ENSDART00000046973
capping protein (actin filament) muscle Z-line, alpha 1a
chr8_+_17168114 2.45 ENSDART00000183901
centromere protein H
chr11_-_15296805 2.45 ENSDART00000124968
ribophorin II
chr13_-_12005429 2.45 ENSDART00000180302
meningioma expressed antigen 5 (hyaluronidase)
chr9_-_3400727 2.45 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr11_-_36230146 2.45 ENSDART00000135888
ENSDART00000189782
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr11_-_17755444 2.45 ENSDART00000154627
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr23_-_19715557 2.45 ENSDART00000143764
ribosomal protein L10
chr14_-_10617923 2.44 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
chr16_-_27224246 2.43 ENSDART00000103257
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr25_-_29072162 2.43 ENSDART00000169269
AT rich interactive domain 3B (BRIGHT-like)
chr8_-_37043900 2.43 ENSDART00000139567
renin binding protein
chr1_-_38170997 2.42 ENSDART00000142811
high mobility group box 2a
chr10_+_18878856 2.42 ENSDART00000024127
protein phosphatase 2, regulatory subunit B, alpha b
chr6_-_57485411 2.41 ENSDART00000011663
small nuclear ribonucleoprotein polypeptides B and B1
chr11_-_7410537 2.41 ENSDART00000009859
adhesion G protein-coupled receptor L4
chr12_-_33789218 2.41 ENSDART00000193258
lethal giant larvae homolog 2 (Drosophila)
chr21_-_26715270 2.41 ENSDART00000053794
barrier to autointegration factor 1
chr12_-_22355430 2.40 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
N-ethylmaleimide-sensitive factor b
chr19_+_1873059 2.39 ENSDART00000145246
small nuclear ribonucleoprotein D1 polypeptide
chr12_+_10443785 2.39 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr21_+_13127742 2.38 ENSDART00000179221
outer dense fiber of sperm tails 2a
chr8_-_4694458 2.37 ENSDART00000019828
zgc:63587
chr18_+_38288877 2.37 ENSDART00000134247
LIM domain only 2 (rhombotin-like 1)
chr10_+_5234327 2.37 ENSDART00000133927
ENSDART00000063120
serine palmitoyltransferase, long chain base subunit 1
chr23_-_21453614 2.35 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr3_-_27647845 2.35 ENSDART00000151625
si:ch211-157c3.4
chr20_+_19066596 2.35 ENSDART00000130271
SRY (sex determining region Y)-box 7
chr8_-_17184482 2.34 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr8_+_12951155 2.34 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr2_-_42035250 2.34 ENSDART00000056460
ENSDART00000140788
guanylate binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of elf2a+elf2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.2 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
1.6 7.9 GO:0060019 radial glial cell differentiation(GO:0060019)
1.4 4.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
1.4 4.1 GO:1990403 embryonic brain development(GO:1990403)
1.3 5.4 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
1.3 3.9 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.3 3.9 GO:0048389 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
1.2 4.9 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.1 5.6 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
1.1 3.3 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
1.1 5.4 GO:0097355 protein localization to heterochromatin(GO:0097355)
1.1 3.2 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.1 3.2 GO:0035142 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
1.0 4.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
1.0 3.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.0 2.9 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.0 4.9 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.9 3.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.9 2.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 2.7 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.9 3.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.9 3.5 GO:0060471 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.9 2.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.8 12.7 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.8 2.5 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.8 2.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.8 3.2 GO:0007063 regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922)
0.8 2.3 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.8 16.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.8 2.3 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.8 9.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.7 4.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.7 2.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.7 5.7 GO:0019405 alditol catabolic process(GO:0019405)
0.7 4.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 2.8 GO:0055016 hypochord development(GO:0055016)
0.7 0.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.7 2.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 2.0 GO:0009193 pyrimidine nucleoside diphosphate metabolic process(GO:0009138) ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.7 4.0 GO:0032447 protein urmylation(GO:0032447)
0.7 4.6 GO:0061056 sclerotome development(GO:0061056)
0.7 4.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.6 1.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.6 2.5 GO:0051645 Golgi localization(GO:0051645)
0.6 2.4 GO:0048211 Golgi vesicle docking(GO:0048211)
0.6 8.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 13.6 GO:0006301 postreplication repair(GO:0006301)
0.6 1.8 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.6 2.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 1.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 2.9 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.6 2.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.6 3.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.5 1.6 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.5 1.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.5 2.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.5 13.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.5 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.5 1.5 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.5 8.2 GO:0051382 kinetochore assembly(GO:0051382)
0.5 2.0 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.5 2.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.5 1.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 2.0 GO:0010259 multicellular organism aging(GO:0010259)
0.5 1.5 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.5 2.0 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.5 5.9 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.5 2.9 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.5 1.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.5 1.4 GO:0002369 T cell cytokine production(GO:0002369)
0.5 1.0 GO:0072695 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247) negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.5 1.4 GO:1905072 cardiac jelly development(GO:1905072)
0.5 7.0 GO:0043248 proteasome assembly(GO:0043248)
0.5 3.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 2.3 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 1.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.5 2.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 1.4 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 3.1 GO:0036010 protein localization to endosome(GO:0036010)
0.4 1.8 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.4 2.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.4 6.6 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.4 3.9 GO:0006465 signal peptide processing(GO:0006465)
0.4 2.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 2.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 1.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 0.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.4 1.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 3.0 GO:0060420 regulation of heart growth(GO:0060420)
0.4 4.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 13.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 1.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 1.2 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.4 2.8 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.4 4.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.4 1.9 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) positive regulation of calcium ion import(GO:0090280)
0.4 3.1 GO:0036372 opsin transport(GO:0036372)
0.4 0.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.4 2.6 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.4 5.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4 2.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 3.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.4 3.7 GO:0070475 rRNA base methylation(GO:0070475)
0.4 1.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.4 3.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 1.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.4 1.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 5.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.4 1.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 1.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.4 1.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.3 1.0 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 1.7 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.3 2.4 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.3 4.2 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.3 2.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.3 1.4 GO:0016038 absorption of visible light(GO:0016038)
0.3 2.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.3 2.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.3 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.3 2.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.3 GO:0040016 embryonic cleavage(GO:0040016)
0.3 1.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 1.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.3 2.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 1.3 GO:0002090 regulation of receptor internalization(GO:0002090)
0.3 1.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.3 1.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 1.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.3 3.1 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.3 1.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 2.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3 1.2 GO:0000338 protein deneddylation(GO:0000338)
0.3 1.8 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.3 11.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 1.8 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 1.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 3.3 GO:0042026 protein refolding(GO:0042026)
0.3 2.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.3 2.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 3.8 GO:0061055 myotome development(GO:0061055)
0.3 2.0 GO:0034508 centromere complex assembly(GO:0034508)
0.3 2.3 GO:0051013 microtubule severing(GO:0051013)
0.3 0.9 GO:0070126 mitochondrial translational termination(GO:0070126)
0.3 5.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 4.2 GO:0045116 protein neddylation(GO:0045116)
0.3 1.4 GO:0043584 nose development(GO:0043584)
0.3 3.0 GO:0034605 cellular response to heat(GO:0034605)
0.3 0.6 GO:0033337 dorsal fin development(GO:0033337)
0.3 1.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 4.6 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 1.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 2.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 3.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.3 0.8 GO:0003156 regulation of organ formation(GO:0003156)
0.3 1.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 6.4 GO:0030497 fatty acid elongation(GO:0030497)
0.3 7.2 GO:0006270 DNA replication initiation(GO:0006270)
0.3 1.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 7.4 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.3 2.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3 1.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.3 2.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.3 1.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 0.7 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 2.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 1.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 2.2 GO:0009791 post-embryonic development(GO:0009791)
0.2 0.7 GO:0001779 natural killer cell differentiation(GO:0001779)
0.2 2.2 GO:1901998 toxin transport(GO:1901998)
0.2 2.2 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 3.9 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.2 2.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 1.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.2 5.7 GO:0007520 myoblast fusion(GO:0007520)
0.2 2.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.8 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.2 3.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 4.0 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 6.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 1.7 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.2 0.4 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.2 1.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 3.1 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.2 0.2 GO:0042727 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.2 1.6 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2 1.6 GO:0035476 angioblast cell migration(GO:0035476)
0.2 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 5.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.2 0.2 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.2 1.8 GO:0031057 negative regulation of histone modification(GO:0031057)
0.2 2.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.2 0.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.2 0.6 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.2 4.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.2 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 1.2 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2 2.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 1.7 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 5.8 GO:0006513 protein monoubiquitination(GO:0006513)
0.2 1.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.4 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.2 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.6 GO:0010893 thyroid hormone generation(GO:0006590) positive regulation of steroid biosynthetic process(GO:0010893)
0.2 1.5 GO:0072178 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.2 0.4 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 0.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.2 0.5 GO:0030238 male sex determination(GO:0030238)
0.2 0.2 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.2 2.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 4.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 1.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 1.2 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.2 1.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.2 0.9 GO:2000381 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) negative regulation of mesoderm development(GO:2000381)
0.2 3.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 11.3 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.2 1.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 0.5 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2 1.7 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 4.7 GO:0016925 protein sumoylation(GO:0016925)
0.2 1.7 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.7 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.2 8.0 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.2 1.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 4.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 2.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 2.8 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 0.8 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.2 0.8 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.2 19.5 GO:0006364 rRNA processing(GO:0006364)
0.2 4.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 40.6 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 2.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 5.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.9 GO:0090314 regulation of protein targeting to membrane(GO:0090313) positive regulation of protein targeting to membrane(GO:0090314)
0.1 0.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.4 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.6 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.9 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.0 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 1.0 GO:0045905 positive regulation of translational termination(GO:0045905)
0.1 1.0 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 1.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 13.8 GO:0008380 RNA splicing(GO:0008380)
0.1 4.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.8 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.1 1.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 1.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 6.6 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.4 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.7 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 2.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.1 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 1.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 2.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 1.0 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 3.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.6 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 1.0 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 1.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 1.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.7 GO:1900744 p38MAPK cascade(GO:0038066) regulation of p38MAPK cascade(GO:1900744)
0.1 4.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 1.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 1.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 5.7 GO:1904018 positive regulation of vasculature development(GO:1904018)
0.1 2.4 GO:0030261 chromosome condensation(GO:0030261)
0.1 2.7 GO:0048264 determination of ventral identity(GO:0048264)
0.1 1.3 GO:0021654 rhombomere boundary formation(GO:0021654)
0.1 3.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 0.2 GO:0051125 regulation of actin nucleation(GO:0051125)
0.1 1.2 GO:0046683 response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.1 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.7 GO:0010573 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 2.2 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 1.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 4.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.8 GO:0032508 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.1 0.1 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1 1.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.7 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.9 GO:0060840 artery development(GO:0060840)
0.1 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.5 GO:0016203 muscle attachment(GO:0016203)
0.1 1.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.6 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.7 GO:0031179 peptide modification(GO:0031179)
0.1 1.9 GO:0031123 RNA 3'-end processing(GO:0031123)
0.1 1.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.4 GO:0031444 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 1.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.5 GO:1902902 mitochondrion morphogenesis(GO:0070584) negative regulation of autophagosome assembly(GO:1902902)
0.1 1.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0045823 cardiolipin metabolic process(GO:0032048) positive regulation of heart contraction(GO:0045823) phosphatidylglycerol metabolic process(GO:0046471)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.0 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 1.8 GO:0090148 membrane fission(GO:0090148)
0.1 0.8 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 6.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.4 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.1 1.3 GO:1903322 positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.1 4.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.7 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.9 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.4 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.6 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 1.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 1.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 4.4 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.6 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 1.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.3 GO:0006154 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 0.9 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.6 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 1.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 3.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 1.8 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.1 2.7 GO:1902275 regulation of chromatin organization(GO:1902275)
0.1 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 3.2 GO:0051607 defense response to virus(GO:0051607)
0.1 0.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304) negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 3.0 GO:0007030 Golgi organization(GO:0007030)
0.1 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.2 GO:0097037 heme export(GO:0097037)
0.1 0.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 0.1 GO:0007143 female meiotic division(GO:0007143)
0.1 0.3 GO:0034552 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.1 GO:0048194 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 1.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 5.5 GO:0006397 mRNA processing(GO:0006397)
0.1 2.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.3 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 1.1 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 1.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 1.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.6 GO:0031623 receptor internalization(GO:0031623)
0.0 0.1 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 1.4 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 2.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 3.3 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 1.3 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.9 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 3.4 GO:0008033 tRNA processing(GO:0008033)
0.0 0.6 GO:0032418 lysosome localization(GO:0032418)
0.0 2.2 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 1.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.5 GO:0042552 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366) myelination(GO:0042552)
0.0 2.4 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0048742 regulation of myotube differentiation(GO:0010830) regulation of skeletal muscle fiber development(GO:0048742)
0.0 1.3 GO:0006396 RNA processing(GO:0006396)
0.0 1.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.7 GO:0009615 response to virus(GO:0009615)
0.0 1.2 GO:0061351 neural precursor cell proliferation(GO:0061351)
0.0 1.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0 0.8 GO:0042246 tissue regeneration(GO:0042246)
0.0 7.2 GO:0070085 glycosylation(GO:0070085)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 1.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.7 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 2.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 1.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.6 GO:0007631 feeding behavior(GO:0007631)
0.0 1.5 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 0.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 2.9 GO:0001947 heart looping(GO:0001947)
0.0 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.9 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.5 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.6 GO:0040029 regulation of gene expression, epigenetic(GO:0040029)
0.0 0.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 1.8 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 1.4 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.9 GO:0060389 pathway-restricted SMAD protein phosphorylation(GO:0060389)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.9 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.1 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0006499 N-terminal protein lipidation(GO:0006498) N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.6 GO:0003014 renal system process(GO:0003014)
0.0 0.3 GO:0072015 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell development(GO:0072015) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell development(GO:0072310) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.0 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400) positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0009086 sulfur amino acid biosynthetic process(GO:0000097) methionine biosynthetic process(GO:0009086)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0060324 face development(GO:0060324)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.0 GO:0016485 protein processing(GO:0016485)
0.0 0.2 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.6 4.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.4 4.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
1.3 3.9 GO:0034709 methylosome(GO:0034709)
1.2 4.9 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
1.1 3.4 GO:0034457 Mpp10 complex(GO:0034457)
1.1 4.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
1.0 7.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.0 4.9 GO:0031415 NatA complex(GO:0031415)
0.9 9.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 2.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.9 3.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.9 6.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.9 4.3 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.8 3.3 GO:0005787 signal peptidase complex(GO:0005787)
0.7 19.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.7 2.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.7 11.9 GO:0005686 U2 snRNP(GO:0005686)
0.7 4.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.7 2.8 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.7 2.7 GO:0097255 R2TP complex(GO:0097255)
0.7 4.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.7 2.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.6 12.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.6 8.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.6 5.5 GO:0000974 Prp19 complex(GO:0000974)
0.6 6.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 1.8 GO:0031251 PAN complex(GO:0031251)
0.6 2.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.6 6.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.6 2.2 GO:0033186 CAF-1 complex(GO:0033186)
0.5 4.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.5 5.6 GO:0005675 holo TFIIH complex(GO:0005675)
0.5 2.8 GO:0031262 Ndc80 complex(GO:0031262)
0.5 2.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.5 6.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5 3.7 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.5 5.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 3.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 1.3 GO:0098536 deuterosome(GO:0098536)
0.4 2.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.4 2.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 1.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 8.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.4 4.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 1.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 2.9 GO:0032019 mitochondrial cloud(GO:0032019)
0.4 1.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 6.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 8.4 GO:0032040 small-subunit processome(GO:0032040)
0.3 3.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 3.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 1.6 GO:0018444 translation release factor complex(GO:0018444)
0.3 3.0 GO:0016272 prefoldin complex(GO:0016272)
0.3 1.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 5.1 GO:0036038 MKS complex(GO:0036038)
0.3 1.3 GO:0071141 SMAD protein complex(GO:0071141)
0.3 1.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 1.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 2.1 GO:1990130 Iml1 complex(GO:1990130)
0.3 1.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.3 1.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 2.0 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.3 5.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 0.9 GO:0097361 CIA complex(GO:0097361)
0.3 1.4 GO:0033263 CORVET complex(GO:0033263)
0.3 5.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 3.0 GO:0008180 COP9 signalosome(GO:0008180)
0.3 1.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 2.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 2.1 GO:0016586 RSC complex(GO:0016586)
0.3 2.6 GO:0070449 elongin complex(GO:0070449)
0.3 4.6 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.3 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.2 3.2 GO:0014704 intercalated disc(GO:0014704)
0.2 1.9 GO:0001772 immunological synapse(GO:0001772)
0.2 1.7 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.7 GO:0071818 BAT3 complex(GO:0071818)
0.2 2.6 GO:0035101 FACT complex(GO:0035101)
0.2 1.0 GO:0070390 transcription export complex 2(GO:0070390)
0.2 3.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 2.5 GO:0045095 keratin filament(GO:0045095)
0.2 1.6 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 1.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 3.7 GO:0005839 proteasome core complex(GO:0005839)
0.2 5.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 1.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 1.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.9 GO:0000124 SAGA complex(GO:0000124)
0.2 1.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 16.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 4.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 1.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 4.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.3 GO:0035517 PR-DUB complex(GO:0035517)
0.2 2.2 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 6.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 0.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 7.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.5 GO:0070187 telosome(GO:0070187)
0.2 3.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 0.7 GO:0016460 myosin II complex(GO:0016460)
0.2 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 0.5 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 1.4 GO:0032021 NELF complex(GO:0032021)
0.2 3.1 GO:0005876 spindle microtubule(GO:0005876)
0.2 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 17.7 GO:0016607 nuclear speck(GO:0016607)
0.2 6.6 GO:0005861 troponin complex(GO:0005861)
0.2 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 3.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0030891 VCB complex(GO:0030891)
0.1 8.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 5.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 6.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 2.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 4.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 2.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 7.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 2.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.1 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 2.0 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 25.1 GO:0005730 nucleolus(GO:0005730)
0.1 3.3 GO:0030496 midbody(GO:0030496)
0.1 0.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.7 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.1 6.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 2.1 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 4.5 GO:0005681 spliceosomal complex(GO:0005681)
0.1 0.8 GO:0031526 brush border membrane(GO:0031526)
0.1 4.1 GO:0016592 mediator complex(GO:0016592)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.3 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 3.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 3.9 GO:0005811 lipid particle(GO:0005811)
0.1 4.1 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.1 GO:0034708 methyltransferase complex(GO:0034708)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 3.5 GO:0016342 catenin complex(GO:0016342)
0.1 5.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 4.7 GO:0005814 centriole(GO:0005814)
0.1 0.5 GO:0030904 retromer complex(GO:0030904)
0.1 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 5.1 GO:0005795 Golgi stack(GO:0005795)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.0 GO:0005884 actin filament(GO:0005884)
0.0 4.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 10.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 1.3 GO:0005694 chromosome(GO:0005694)
0.0 3.2 GO:0031674 I band(GO:0031674)
0.0 5.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 148.3 GO:0005634 nucleus(GO:0005634)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 4.2 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 6.4 GO:0009986 cell surface(GO:0009986)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 1.5 GO:0005925 focal adhesion(GO:0005925)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.6 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.3 6.7 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
1.2 3.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.1 3.4 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
1.1 4.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.1 12.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.1 3.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.0 4.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.9 2.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 2.7 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.9 2.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.8 5.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.8 2.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.8 3.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.7 2.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.7 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.7 5.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.7 3.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.7 3.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.7 2.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.6 2.6 GO:0003796 lysozyme activity(GO:0003796)
0.6 12.7 GO:0070411 I-SMAD binding(GO:0070411)
0.6 2.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.6 4.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.6 2.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.6 6.6 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.6 2.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.6 4.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 2.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 3.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 4.8 GO:0043515 kinetochore binding(GO:0043515)
0.5 3.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 1.5 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.5 1.4 GO:0030623 U5 snRNA binding(GO:0030623)
0.5 5.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.5 2.4 GO:0039706 co-receptor binding(GO:0039706)
0.4 3.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 3.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.4 1.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.4 1.3 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.4 2.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 2.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 1.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 1.7 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 2.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.4 2.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 1.6 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.4 8.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 1.6 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.4 2.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 1.9 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.4 1.5 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.4 4.9 GO:0030515 snoRNA binding(GO:0030515)
0.4 1.1 GO:0001016 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.4 1.5 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.4 1.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.4 1.1 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.4 9.1 GO:0005112 Notch binding(GO:0005112)
0.4 1.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.4 1.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.4 1.8 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.3 1.4 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.3 3.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 2.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.3 1.6 GO:0008430 selenium binding(GO:0008430)
0.3 1.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 2.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 1.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.3 2.5 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 6.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.3 1.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 0.9 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.3 3.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 1.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 5.1 GO:0045159 myosin II binding(GO:0045159)
0.3 1.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.3 1.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 0.8 GO:0045545 syndecan binding(GO:0045545)
0.3 2.0 GO:0019809 spermidine binding(GO:0019809)
0.3 7.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 5.5 GO:0097602 cullin family protein binding(GO:0097602)
0.3 1.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 3.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.3 1.3 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.3 2.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 1.0 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.3 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 1.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 1.8 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 1.7 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 2.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 3.1 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 1.0 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.2 4.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 1.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 0.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 3.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 0.6 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 1.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 4.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 7.5 GO:0019003 GDP binding(GO:0019003)
0.2 1.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 1.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 3.4 GO:0008301 DNA binding, bending(GO:0008301)
0.2 0.8 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2 0.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 3.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.9 GO:0030332 cyclin binding(GO:0030332)
0.2 3.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.0 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.2 0.8 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 2.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 2.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.8 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.2 2.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 3.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 2.7 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 2.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 0.9 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 0.5 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2 1.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 3.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 1.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 2.1 GO:0005537 mannose binding(GO:0005537)
0.2 1.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 2.9 GO:0015026 coreceptor activity(GO:0015026)
0.2 7.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 1.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 5.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.8 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 2.3 GO:0031386 protein tag(GO:0031386)
0.1 1.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 2.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 7.1 GO:0031491 nucleosome binding(GO:0031491)
0.1 8.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.7 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.5 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 1.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 4.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 3.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 10.2 GO:0003724 RNA helicase activity(GO:0003724)
0.1 2.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 2.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0051380 norepinephrine binding(GO:0051380)
0.1 7.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 4.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 4.7 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.4 GO:0043531 ADP binding(GO:0043531)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.9 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 2.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 2.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 5.2 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 2.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 0.3 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 2.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 2.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.9 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 13.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.3 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 3.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 2.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 4.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 6.4 GO:0045296 cadherin binding(GO:0045296)
0.1 2.0 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 6.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 5.7 GO:0042802 identical protein binding(GO:0042802)
0.1 0.7 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 3.6 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.1 0.3 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 67.4 GO:0003723 RNA binding(GO:0003723)
0.1 3.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 6.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.0 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 1.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 7.0 GO:0003712 transcription factor activity, protein binding(GO:0000988) transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 7.5 GO:0060090 binding, bridging(GO:0060090)
0.0 7.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.6 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.6 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 9.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 20.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.2 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 3.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 56.4 GO:0003677 DNA binding(GO:0003677)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 4.1 GO:0004175 endopeptidase activity(GO:0004175)
0.0 7.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 2.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 2.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
1.0 13.8 PID ALK2 PATHWAY ALK2 signaling events
0.9 7.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.7 11.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 14.4 PID AURORA B PATHWAY Aurora B signaling
0.3 7.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 7.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 1.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 4.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 4.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 3.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 5.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 3.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 6.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 3.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 9.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.9 PID AURORA A PATHWAY Aurora A signaling
0.1 6.5 PID E2F PATHWAY E2F transcription factor network
0.1 5.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 9.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.8 PID P73PATHWAY p73 transcription factor network
0.1 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.1 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 5.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 12.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.9 9.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.8 7.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.7 8.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.6 18.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.6 43.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.5 14.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5 8.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 4.7 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.4 8.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 3.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 1.8 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.4 2.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.4 11.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 14.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 2.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 3.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.3 1.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.3 4.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3 14.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 5.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 3.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 4.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.2 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 5.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 3.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 2.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.2 3.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 6.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 2.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 2.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 2.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 1.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 4.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 7.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.5 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 2.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 5.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 3.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 2.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 6.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 2.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 1.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 5.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 2.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.3 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks