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PRJEB1986: zebrafish developmental stages transcriptome

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Results for egr2a+egr2b

Z-value: 1.05

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Transcription factors associated with egr2a+egr2b

Gene Symbol Gene ID Gene Info
ENSDARG00000042826 early growth response 2b
ENSDARG00000044098 early growth response 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr2adr11_v1_chr17_-_43665366_43665366-0.821.7e-05Click!
egr2bdr11_v1_chr12_-_8504278_8504278-0.691.2e-03Click!

Activity profile of egr2a+egr2b motif

Sorted Z-values of egr2a+egr2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_22535 6.35 ENSDART00000157877

chr14_+_15155684 5.15 ENSDART00000167966
zgc:158852
chr17_+_27456804 3.75 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr25_+_24250247 3.69 ENSDART00000064646
transmembrane protein 86A
chr3_-_61185746 3.68 ENSDART00000028219
parvalbumin 4
chr25_-_207214 3.19 ENSDART00000193448

chr20_-_54462551 3.15 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr6_-_35446110 2.88 ENSDART00000058773
regulator of G protein signaling 16
chr8_+_34731982 2.81 ENSDART00000066050
4-hydroxyphenylpyruvate dioxygenase b
chr11_+_7324704 2.77 ENSDART00000031937
DIRAS family, GTP-binding RAS-like 1a
chr16_-_12173554 2.61 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr23_+_20422661 2.56 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr2_+_47582488 2.46 ENSDART00000149967
secretogranin II (chromogranin C), b
chr19_+_342094 2.39 ENSDART00000151013
ENSDART00000187622
endosulfine alpha a
chr23_-_637347 2.32 ENSDART00000132175
L1 cell adhesion molecule, paralog b
chr14_-_2933185 2.29 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr2_+_47582681 2.15 ENSDART00000187579
secretogranin II (chromogranin C), b
chr2_+_59015878 2.12 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr25_-_8602437 2.10 ENSDART00000171200
Rh family, C glycoprotein b
chr7_-_38612230 2.06 ENSDART00000173678
C1q and TNF related 4
chr8_+_23165749 2.04 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr3_+_60007703 2.03 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
chr24_-_31439841 2.01 ENSDART00000169952
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr14_+_2243 1.93 ENSDART00000191193
cytokine like 1
chr5_-_26093945 1.90 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr6_-_16406210 1.90 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr25_+_34984333 1.87 ENSDART00000154760
coiled-coil domain containing 136b
chr6_+_40661703 1.85 ENSDART00000142492
enolase 1b, (alpha)
chr18_+_402048 1.84 ENSDART00000166345
glucose-6-phosphate isomerase b
chr6_-_15604157 1.81 ENSDART00000141597
leucine rich repeat (in FLII) interacting protein 1b
chr24_+_3963684 1.79 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
phosphofructokinase, platelet a
chr17_+_46387086 1.78 ENSDART00000157079
si:dkey-206p8.1
chr8_+_24854600 1.75 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr21_+_28958471 1.75 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_-_12173399 1.72 ENSDART00000142574
calsyntenin 3
chr6_+_42338309 1.72 ENSDART00000015277
glutathione peroxidase 1b
chr21_+_5169154 1.68 ENSDART00000102559
zgc:122979
chr12_+_18606140 1.67 ENSDART00000161128
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr11_+_77526 1.67 ENSDART00000193521

chr6_+_21740672 1.65 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr3_+_19299309 1.64 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr6_+_41503854 1.62 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cytokine inducible SH2-containing protein
chr1_+_32528097 1.61 ENSDART00000128317
neuroligin 4a
chr1_-_50438247 1.58 ENSDART00000114098
dickkopf WNT signaling pathway inhibitor 2
chr23_+_44307996 1.57 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr19_-_10196370 1.56 ENSDART00000091707
D site albumin promoter binding protein a
chr10_+_110868 1.55 ENSDART00000135572
ENSDART00000190467
ENSDART00000056672
phosphatidylinositol glycan anchor biosynthesis, class P
chr24_+_26379441 1.53 ENSDART00000137786
si:ch211-230g15.5
chr9_-_54001502 1.49 ENSDART00000085253
midline 1
chr20_-_14665002 1.47 ENSDART00000152816
secernin 2
chr13_+_12739283 1.47 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr1_+_1599979 1.47 ENSDART00000097626
urotensin II-related peptide
chr11_+_1796426 1.46 ENSDART00000173330
low density lipoprotein receptor-related protein 1Aa
chr7_+_67325933 1.43 ENSDART00000170575
ENSDART00000183342
nuclear factor of activated T cells 5b
chr23_-_29556844 1.43 ENSDART00000138021
retinol binding protein 7a, cellular
chr16_-_12316979 1.40 ENSDART00000182392
transient receptor potential cation channel, subfamily V, member 6
chr11_-_24191928 1.39 ENSDART00000136827
SRY (sex determining region Y)-box 12
chr14_+_909769 1.39 ENSDART00000021346
ENSDART00000172777
ADP-ribosylation factor-like 3, like 2
chr23_-_32156278 1.38 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr16_-_6821927 1.38 ENSDART00000149070
ENSDART00000149570
myelin basic protein b
chr21_-_43952958 1.38 ENSDART00000039571
calcium/calmodulin-dependent protein kinase II alpha
chr23_+_41799748 1.37 ENSDART00000144257
prodynorphin
chr8_+_49975160 1.36 ENSDART00000156403
ENSDART00000080135
glutamine--fructose-6-phosphate transaminase 1
chr5_-_43071058 1.34 ENSDART00000165546
si:dkey-245n4.2
chr7_-_29534001 1.29 ENSDART00000124028
annexin A2b
chr20_+_1398564 1.29 ENSDART00000002242
liver-enriched gene 1, tandem duplicate 2
chr25_-_7999756 1.26 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr21_+_11415224 1.26 ENSDART00000049036
zgc:92275
chr11_+_2855430 1.24 ENSDART00000172837
kinesin family member 21B
chr16_+_68069 1.22 ENSDART00000185385
ENSDART00000159652
SRY (sex determining region Y)-box 4b
chr20_-_45661049 1.21 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr3_-_28075756 1.20 ENSDART00000122037
RNA binding fox-1 homolog 1
chr23_-_12158685 1.20 ENSDART00000135035
family with sequence similarity 217, member B
chr20_+_13969414 1.20 ENSDART00000049864
retinal degeneration 3
chr7_-_13882988 1.19 ENSDART00000169828
retinaldehyde binding protein 1a
chr17_-_20897407 1.18 ENSDART00000149481
ankyrin 3b
chr2_-_31936966 1.18 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amphiphysin
chr16_+_52105227 1.16 ENSDART00000150025
ENSDART00000097863
si:ch73-373m9.1
chr2_+_30147504 1.13 ENSDART00000190947
potassium voltage-gated channel, Shab-related subfamily, member 2
chr17_+_30587333 1.12 ENSDART00000156500
NHS-like 1a
chr1_-_44940830 1.12 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr7_+_38510197 1.11 ENSDART00000173468
ENSDART00000100479
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr1_-_7917062 1.11 ENSDART00000177068
monocyte to macrophage differentiation-associated 2b
chr6_-_15604417 1.11 ENSDART00000157817
leucine rich repeat (in FLII) interacting protein 1b
chr10_-_15053507 1.10 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr21_-_43949208 1.10 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr19_+_14573998 1.10 ENSDART00000022076
family with sequence similarity 46, member Bb
chr2_+_38924975 1.09 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr11_+_30161168 1.09 ENSDART00000157385
cyclin-dependent kinase-like 5
chr4_+_19534833 1.08 ENSDART00000140028
leucine rich repeat containing 4.1
chr20_-_53366137 1.08 ENSDART00000146001
WAS protein family, member 1
chr24_+_32472155 1.07 ENSDART00000098859
neuronal differentiation 6a
chr7_-_52849913 1.06 ENSDART00000174133
ENSDART00000172951
microtubule-associated protein 1Aa
chr3_+_16762483 1.06 ENSDART00000132732
transmembrane protein 86B
chr16_+_10918252 1.05 ENSDART00000172949
POU class 2 homeobox 2a
chr5_-_68022631 1.04 ENSDART00000143199
WAS protein family, member 3a
chr4_+_2619132 1.04 ENSDART00000128807
G protein-coupled receptor 22a
chr13_-_37653840 1.04 ENSDART00000143806
si:dkey-188i13.11
chr2_-_155270 1.03 ENSDART00000131177
adenylate cyclase 1b
chr16_-_2414063 1.02 ENSDART00000073621
zgc:152945
chr10_+_1668106 1.02 ENSDART00000142278
small G protein signaling modulator 1b
chr11_+_3254524 1.01 ENSDART00000159459
premelanosome protein a
chr6_-_25181012 1.00 ENSDART00000161585
leucine rich repeat containing 8 VRAC subunit Db
chr23_+_43834376 0.99 ENSDART00000148989
si:ch211-149b19.4
chr7_-_7845540 0.99 ENSDART00000166280
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr3_+_16722014 0.99 ENSDART00000008711
glycogen synthase 1 (muscle)
chr18_+_41495841 0.99 ENSDART00000098671
si:ch211-203b8.6
chr1_-_46632948 0.99 ENSDART00000148893
ENSDART00000053232
cytidine and dCMP deaminase domain containing 1
chr25_+_37348730 0.98 ENSDART00000156639
peptidase domain containing associated with muscle regeneration 1
chr8_-_22739757 0.97 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr19_+_5480327 0.97 ENSDART00000148794
junction plakoglobin b
chr24_-_17892325 0.97 ENSDART00000154039
ENSDART00000185619
ENSDART00000178326
contactin associated protein like 2a
chr18_-_16179129 0.96 ENSDART00000125353
solute carrier family 6 (neutral amino acid transporter), member 15
chr15_+_9294620 0.95 ENSDART00000133588
ENSDART00000140009
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr15_-_47193564 0.94 ENSDART00000172453
limbic system-associated membrane protein
chr7_-_6458222 0.94 ENSDART00000172861
zgc:165555
chr15_-_5467477 0.94 ENSDART00000123839
arrestin, beta 1
chr19_+_9305964 0.93 ENSDART00000136241
si:ch73-15n24.1
chr3_+_22273123 0.93 ENSDART00000044157
sodium channel, voltage-gated, type IV, alpha, b
chr21_-_43398122 0.93 ENSDART00000050533
cyclin I family, member 2
chr24_+_35564668 0.92 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr12_+_2522642 0.92 ENSDART00000152567
FERM and PDZ domain containing 2
chr25_-_19395476 0.91 ENSDART00000182622
microtubule-associated protein 1Ab
chr13_-_49666615 0.91 ENSDART00000148083
translocase of outer mitochondrial membrane 20
chr11_-_33919309 0.91 ENSDART00000078202
phosphorylase kinase, alpha 2 (liver)
chr3_+_40315410 0.91 ENSDART00000083241
ENSDART00000132827
solute carrier family 29 (equilibrative nucleoside transporter), member 4
chr14_-_21218891 0.91 ENSDART00000158294
protein phosphatase 2, regulatory subunit B, gamma b
chr16_+_10963602 0.91 ENSDART00000141032
POU class 2 homeobox 2a
chr2_-_48966431 0.91 ENSDART00000147948
potassium inwardly-rectifying channel, subfamily J, member 9
chr3_+_51684963 0.90 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
BAI1-associated protein 2a
chr21_+_7900107 0.90 ENSDART00000056560
cholesterol 25-hydroxylase like 2
chr23_+_46183410 0.90 ENSDART00000167596
ENSDART00000151149
ENSDART00000150896
bloodthirsty-related gene family, member 31
chr1_-_59176949 0.89 ENSDART00000128742

chr25_-_10564721 0.89 ENSDART00000154776
galanin/GMAP prepropeptide
chr24_+_2519761 0.89 ENSDART00000106619
neuritin 1a
chr5_+_51443009 0.88 ENSDART00000083350
Ras protein-specific guanine nucleotide-releasing factor 2b
chr1_-_22861348 0.87 ENSDART00000139412
si:dkey-92j12.6
chr7_-_10560964 0.87 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr5_-_1999417 0.87 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
chr16_+_17389116 0.87 ENSDART00000103750
ENSDART00000173448
family with sequence similarity 131, member Bb
chr15_+_3284416 0.86 ENSDART00000187665
ENSDART00000171723
forkhead box O1 a
chr25_-_35046114 0.85 ENSDART00000185267
zgc:165555
chr12_-_15620090 0.85 ENSDART00000038032
acyl-CoA binding domain containing 4
chr11_+_6819050 0.84 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr3_-_30061985 0.84 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr15_-_16121496 0.84 ENSDART00000128624
uncharacterized serine/threonine-protein kinase SgK494a
chr17_-_20897250 0.83 ENSDART00000088106
ankyrin 3b
chr23_+_41800052 0.82 ENSDART00000141484
prodynorphin
chr1_-_19845378 0.81 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr5_+_31820264 0.81 ENSDART00000110974
zinc finger, DHHC-type containing 12b
chr7_+_30867008 0.81 ENSDART00000193106
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr13_+_31757331 0.81 ENSDART00000044282
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr8_-_14144707 0.81 ENSDART00000148061
si:dkey-6n6.1
chr13_+_51853716 0.81 ENSDART00000175341
ENSDART00000187855

chr14_+_11430796 0.80 ENSDART00000165275
si:ch211-153b23.3
chr13_-_40238813 0.80 ENSDART00000044963
lysyl oxidase-like 4
chr21_-_43398457 0.78 ENSDART00000166530
cyclin I family, member 2
chr22_+_883678 0.78 ENSDART00000140588
serine/threonine kinase 38b
chr10_+_32646402 0.78 ENSDART00000137244
zinc finger and BTB domain containing 21
chr7_-_6352569 0.78 ENSDART00000173074
zgc:165555
chr23_+_16633951 0.77 ENSDART00000109537
ENSDART00000193323
syntaphilin b
chr1_+_31942961 0.77 ENSDART00000007522
anosmin 1a
chr11_-_33919014 0.77 ENSDART00000181203
phosphorylase kinase, alpha 2 (liver)
chr23_-_32100106 0.77 ENSDART00000044658
LETM1 domain containing 1
chr18_+_15106518 0.77 ENSDART00000168639
cryptochrome circadian clock 1ab
chr21_-_7882905 0.76 ENSDART00000056561
S100 calcium binding protein Z
chr10_+_252425 0.76 ENSDART00000059478
leucine rich repeat containing 32
chr11_-_37880492 0.75 ENSDART00000102868
ethanolamine kinase 2
chr15_+_47746176 0.75 ENSDART00000154481
ENSDART00000160914
StAR-related lipid transfer (START) domain containing 10
chr10_+_2234283 0.75 ENSDART00000136363
contactin associated protein like 3
chr10_+_26571174 0.75 ENSDART00000148617
ENSDART00000112956
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr15_+_46344655 0.75 ENSDART00000155893
si:ch1073-340i21.2
chr9_+_51784922 0.73 ENSDART00000125850
CD302 molecule
chr11_-_33960318 0.73 ENSDART00000087597
collagen, type VI, alpha 2
chr19_-_36675023 0.73 ENSDART00000132471
CUB and Sushi multiple domains 2
chr11_+_3254252 0.73 ENSDART00000123568
premelanosome protein a
chr25_+_34888886 0.72 ENSDART00000035245
spire-type actin nucleation factor 2
chr7_-_20241346 0.72 ENSDART00000173619
ENSDART00000127699
si:ch73-335l21.4
chr12_-_13886952 0.72 ENSDART00000110503
ADAM metallopeptidase domain 11
chr10_-_19497914 0.71 ENSDART00000132084
si:ch211-127i16.2
chr3_-_49504023 0.70 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr2_+_37480669 0.70 ENSDART00000029801
signal peptide peptidase-like 2
chr18_+_12147971 0.70 ENSDART00000162067
ENSDART00000168386
FYVE, RhoGEF and PH domain containing 4a
chr6_-_8580857 0.70 ENSDART00000138858
ENSDART00000041142
myosin, heavy chain 11a, smooth muscle
chr2_-_24603325 0.70 ENSDART00000113356
CREB regulated transcription coactivator 1a
chr8_-_30338872 0.69 ENSDART00000137583
dedicator of cytokinesis 8
chr19_-_6193448 0.69 ENSDART00000151405
Ets2 repressor factor
chr1_-_28629471 0.69 ENSDART00000121758
endothelin receptor Ba
chr17_-_14726824 0.69 ENSDART00000162947
si:ch73-305o9.3
chr22_+_18786797 0.68 ENSDART00000141864
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr4_-_16644708 0.68 ENSDART00000042307
SIN3-HDAC complex associated factor
chr24_-_14711597 0.68 ENSDART00000131830
junctophilin 1a
chr3_+_16976095 0.68 ENSDART00000112450
caveolae associated protein 1a
chr18_-_21806613 0.67 ENSDART00000145721
neuritin 1-like a
chr25_+_1304173 0.67 ENSDART00000155229
relaxin/insulin-like family peptide receptor 3.3b
chr25_-_10565006 0.66 ENSDART00000130608
ENSDART00000190212
galanin/GMAP prepropeptide
chr9_-_2573121 0.65 ENSDART00000181340
secernin 3
chr2_-_7431590 0.65 ENSDART00000185699
agouti signaling protein, nonagouti homolog (mouse) 2b
chr12_-_41684729 0.64 ENSDART00000184461
Janus kinase and microtubule interacting protein 3
chr8_+_1284784 0.63 ENSDART00000061663
F-box and leucine-rich repeat protein 17

Network of associatons between targets according to the STRING database.

First level regulatory network of egr2a+egr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.6 1.8 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.6 1.7 GO:0097435 fibril organization(GO:0097435)
0.6 2.8 GO:0061551 trigeminal ganglion development(GO:0061551)
0.5 1.6 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.5 4.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 2.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 2.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.4 1.6 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578) gamma-aminobutyric acid receptor clustering(GO:0097112)
0.4 1.4 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3 1.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 1.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 1.7 GO:0010269 response to selenium ion(GO:0010269)
0.3 0.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 1.6 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.3 1.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.2 0.9 GO:0001774 microglial cell activation(GO:0001774)
0.2 1.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.6 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.2 3.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 3.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 1.0 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 1.4 GO:0071632 optomotor response(GO:0071632)
0.2 1.9 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.2 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 1.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 0.8 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 1.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 2.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.7 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.1 0.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 3.8 GO:0051289 protein homotetramerization(GO:0051289)
0.1 2.6 GO:0014823 response to activity(GO:0014823)
0.1 2.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.9 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 3.2 GO:0019319 hexose biosynthetic process(GO:0019319)
0.1 0.6 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 0.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 4.2 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.7 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 2.6 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.7 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 1.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.8 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.7 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.1 1.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.8 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.1 0.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.9 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.3 GO:0019860 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860) 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.2 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 1.7 GO:0060972 left/right pattern formation(GO:0060972)
0.1 1.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.0 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.6 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 2.7 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.8 GO:0030168 platelet activation(GO:0030168)
0.0 3.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.7 GO:0050935 iridophore differentiation(GO:0050935)
0.0 1.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 2.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.3 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.3 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0006096 glycolytic process(GO:0006096)
0.0 0.1 GO:0097037 heme export(GO:0097037)
0.0 0.4 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.5 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.6 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.1 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 1.4 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0060077 inhibitory synapse(GO:0060077)
0.4 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.8 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 3.1 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 1.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.1 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0033010 paranodal junction(GO:0033010)
0.1 0.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0043209 myelin sheath(GO:0043209)
0.1 0.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 5.3 GO:0030141 secretory granule(GO:0030141)
0.1 1.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.6 GO:0005861 troponin complex(GO:0005861)
0.1 2.2 GO:0043679 axon terminus(GO:0043679)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.0 1.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.8 GO:0000786 nucleosome(GO:0000786)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 4.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 6.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 4.2 GO:0005764 lysosome(GO:0005764)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0098978 glutamatergic synapse(GO:0098978)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.6 4.7 GO:0016803 ether hydrolase activity(GO:0016803)
0.4 1.8 GO:0071253 connexin binding(GO:0071253)
0.4 2.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.4 1.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.4 1.8 GO:0039706 co-receptor binding(GO:0039706)
0.3 3.1 GO:0005522 profilin binding(GO:0005522)
0.3 1.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 1.4 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.3 0.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.0 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 1.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 2.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.8 GO:0070052 collagen V binding(GO:0070052)
0.2 1.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 2.2 GO:0031628 opioid receptor binding(GO:0031628)
0.2 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 2.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 1.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.8 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 2.0 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 0.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.9 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.4 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 2.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 2.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.8 GO:0019003 GDP binding(GO:0019003)
0.1 0.3 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 1.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.9 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 1.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 1.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 1.0 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.7 GO:0015293 symporter activity(GO:0015293)
0.0 0.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.5 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 2.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 2.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 3.5 GO:0015631 tubulin binding(GO:0015631)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.8 ST ADRENERGIC Adrenergic Pathway
0.1 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters