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PRJEB1986: zebrafish developmental stages transcriptome

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Results for cux2b

Z-value: 0.63

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Transcription factors associated with cux2b

Gene Symbol Gene ID Gene Info
ENSDARG00000086345 cut-like homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cux2bdr11_v1_chr8_-_4327473_4327473-0.145.6e-01Click!

Activity profile of cux2b motif

Sorted Z-values of cux2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_48039400 1.54 ENSDART00000166748
ENSDART00000165921
colony stimulating factor 3 (granulocyte) b
chr2_-_42958619 1.24 ENSDART00000144317
otoconin 90
chr12_-_20340543 1.17 ENSDART00000055623
hemoglobin beta embryonic-3
chr7_+_32695954 0.92 ENSDART00000184425
solute carrier family 39 (zinc transporter), member 13
chr23_-_45705525 0.80 ENSDART00000148959
endothelin receptor type Ab
chr21_-_34844059 0.69 ENSDART00000136402
zgc:56585
chr1_+_277731 0.67 ENSDART00000133431
centromere protein E
chr16_+_54210554 0.66 ENSDART00000172622
X-ray repair complementing defective repair in Chinese hamster cells 1
chr6_-_17999776 0.64 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
regulatory associated protein of MTOR, complex 1
chr19_-_41518922 0.63 ENSDART00000164483
ENSDART00000062080
chromatin accessibility complex 1
chr3_-_61387273 0.63 ENSDART00000156479
zinc finger protein 1143
chr16_+_54209504 0.63 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr23_+_12454542 0.62 ENSDART00000182259
ENSDART00000193043
si:ch211-153a8.4
chr7_-_17297156 0.62 ENSDART00000161336
novel immune-type receptor 11a
chr17_-_40110782 0.59 ENSDART00000126929
si:dkey-187k19.2
chr12_+_16953415 0.53 ENSDART00000020824
pantothenate kinase 1b
chr4_+_5334202 0.51 ENSDART00000150409
APEX nuclease (multifunctional DNA repair enzyme) 1
chr20_-_35246150 0.50 ENSDART00000090549
frizzled class receptor 3a
chr1_+_292545 0.50 ENSDART00000148261
centromere protein E
chr18_-_14677936 0.49 ENSDART00000111995
si:dkey-238o13.4
chr16_+_29509133 0.49 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr21_-_37973819 0.49 ENSDART00000133405
ripply transcriptional repressor 1
chr13_-_21650404 0.49 ENSDART00000078352
tetraspanin 14
chr21_-_2261720 0.49 ENSDART00000170161
si:ch73-299h12.2
chr4_+_5334439 0.48 ENSDART00000180644
APEX nuclease (multifunctional DNA repair enzyme) 1
chr11_-_35171768 0.48 ENSDART00000192896
TRAF-interacting protein
chr9_-_55128839 0.48 ENSDART00000085135
transducin beta like 1 X-linked
chr3_-_61362398 0.47 ENSDART00000156177
si:dkey-111k8.3
chr14_-_970853 0.46 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr22_-_3564563 0.46 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr18_+_44630415 0.46 ENSDART00000098540
BRD4 interacting chromatin remodeling complex associated protein
chr9_-_48371379 0.46 ENSDART00000115121
collagen, type XXVIII, alpha 2a
chr7_+_1579236 0.46 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr15_+_29472065 0.45 ENSDART00000154343
glycerophosphodiester phosphodiesterase domain containing 5b
chr4_+_27018663 0.45 ENSDART00000180778

chr14_+_52481288 0.45 ENSDART00000169164
ENSDART00000159297
transcription elongation regulator 1a (CA150)
chr7_-_16597130 0.45 ENSDART00000144118
E2F transcription factor 8
chr2_+_45300512 0.45 ENSDART00000144704
calmodulin regulated spectrin-associated protein family, member 2b
chr25_+_3648497 0.45 ENSDART00000160017

chr21_+_45268112 0.45 ENSDART00000157136
transcription factor 7
chr17_-_2578026 0.45 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr22_-_34979139 0.44 ENSDART00000116455
ENSDART00000133537
Rho GTPase activating protein 19
chr4_+_288633 0.44 ENSDART00000183304

chr4_+_5334707 0.43 ENSDART00000150620
APEX nuclease (multifunctional DNA repair enzyme) 1
chr25_+_22320738 0.43 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr20_-_16078741 0.43 ENSDART00000021550
Ral GEF with PH domain and SH3 binding motif 2
chr21_-_19919918 0.42 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
protein phosphatase 1, regulatory subunit 3B
chr24_+_38301080 0.42 ENSDART00000105672
myosin binding protein C, fast type b
chr1_+_38153944 0.42 ENSDART00000135666
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr23_-_43486714 0.42 ENSDART00000169726
E2F transcription factor 1
chr21_+_38855551 0.41 ENSDART00000171977
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr23_+_4373360 0.41 ENSDART00000144061
protein tyrosine phosphatase domain containing 1b
chr15_+_11814969 0.41 ENSDART00000127248

chr20_+_21391181 0.41 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jagged 2b
chr19_-_10207103 0.41 ENSDART00000151629
zinc finger protein 865
chr7_+_30626378 0.41 ENSDART00000173533
ENSDART00000052541
cyclin B2
chr9_+_32073606 0.41 ENSDART00000184170
ENSDART00000180355
ENSDART00000110204
ENSDART00000123278
phosphoinositide kinase, FYVE finger containing
chr5_+_31779911 0.40 ENSDART00000098163
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr7_-_5375214 0.40 ENSDART00000033316
VANGL planar cell polarity protein 2
chr12_-_611367 0.40 ENSDART00000152286
wu:fj29h11
chr6_+_20647155 0.40 ENSDART00000193477
solute carrier family 19 (folate transporter), member 1
chr6_+_18544791 0.39 ENSDART00000167463
ENSDART00000169599
ATPase family, AAA domain containing 5b
chr7_-_16596938 0.39 ENSDART00000134548
E2F transcription factor 8
chr17_-_2590222 0.39 ENSDART00000185711

chr11_-_22605981 0.39 ENSDART00000186923
myogenin
chr17_-_15189397 0.38 ENSDART00000133710
ENSDART00000110507
WD repeat and HMG-box DNA binding protein 1
chr16_+_35870456 0.38 ENSDART00000184321
thyroid hormone receptor associated protein 3a
chr16_-_30564319 0.38 ENSDART00000145087
lamin A
chr2_+_21048661 0.38 ENSDART00000156876
ras responsive element binding protein 1b
chr19_-_18130567 0.38 ENSDART00000190659
ENSDART00000022803
sorting nexin 10a
chr18_-_15610856 0.37 ENSDART00000099849
aryl hydrocarbon receptor nuclear translocator-like 2
chr9_+_22780901 0.37 ENSDART00000110992
ENSDART00000143972
replication timing regulatory factor 1
chr5_-_28767573 0.36 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr9_+_13120419 0.36 ENSDART00000141005
family with sequence similarity 117, member Bb
chr16_-_26435431 0.36 ENSDART00000187526
multiple EGF-like-domains 8
chr5_+_37729207 0.36 ENSDART00000184378
CDC42 effector protein (Rho GTPase binding) 2
chr3_-_62527675 0.36 ENSDART00000155048
ENSDART00000064500
SRY (sex determining region Y)-box 9b
chr13_+_1726953 0.36 ENSDART00000103004
zmp:0000000760
chr21_+_45267589 0.36 ENSDART00000182963
ENSDART00000155681
ENSDART00000192632
transcription factor 7
chr23_+_21405201 0.36 ENSDART00000144409
intermediate filament family orphan 2a
chr1_+_16621345 0.36 ENSDART00000149026
pericentriolar material 1
chr13_+_46941930 0.35 ENSDART00000056962
F-box protein 5
chr22_+_18349794 0.35 ENSDART00000186580
GATA zinc finger domain containing 2Ab
chr14_+_49376011 0.34 ENSDART00000020961
TNFAIP3 interacting protein 1
chr3_+_62339264 0.34 ENSDART00000174569

chr5_-_20205075 0.34 ENSDART00000051611
D-amino-acid oxidase, tandem duplicate 3
chr13_+_45967179 0.33 ENSDART00000074499
oligodendrocyte transcription factor 4
chr8_-_18880399 0.33 ENSDART00000169043
SH3-domain GRB2-like 1b
chr25_+_18964782 0.33 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
chr4_-_77135340 0.33 ENSDART00000180581
ENSDART00000179901

chr25_-_37262220 0.32 ENSDART00000153789
ENSDART00000155182
ring finger and WD repeat domain 3
chr19_+_16015881 0.32 ENSDART00000187135
CTP synthase 1a
chr1_+_21563311 0.32 ENSDART00000147076
ENSDART00000006147
primase and polymerase (DNA-directed)
chr8_-_53960349 0.32 ENSDART00000160074
cyclin-dependent kinase 11B
chr10_-_21545091 0.32 ENSDART00000029122
ENSDART00000132207
zgc:165539
chr7_+_61480296 0.31 ENSDART00000083255
ADAM metallopeptidase domain 19a
chr22_-_7539414 0.31 ENSDART00000159083

chr16_+_28994709 0.31 ENSDART00000088023
gon-4-like (C. elegans)
chr19_+_16016038 0.31 ENSDART00000131319
CTP synthase 1a
chr3_+_60721342 0.31 ENSDART00000157772
forkhead box J1a
chr2_+_35880600 0.31 ENSDART00000004277
laminin, gamma 1
chr10_+_13209580 0.31 ENSDART00000000887
ENSDART00000136932
Ras association (RalGDS/AF-6) domain family 6
chr4_+_5832311 0.31 ENSDART00000121743
ENSDART00000158233
ENSDART00000165187
si:ch73-352p4.5
chr7_-_16598212 0.30 ENSDART00000128488
E2F transcription factor 8
chr23_+_32101202 0.30 ENSDART00000000992
zgc:56699
chr4_-_45115963 0.30 ENSDART00000137248
si:dkey-51d8.6
chr2_-_45510699 0.30 ENSDART00000024034
ENSDART00000145634
G protein signaling modulator 2
chr23_+_43424518 0.30 ENSDART00000022498
TELO2 interacting protein 1
chr3_-_61377127 0.29 ENSDART00000155932
si:dkey-111k8.2
chr14_+_52413846 0.29 ENSDART00000160952
nitric oxide associated 1
chr2_-_45510223 0.29 ENSDART00000113058
G protein signaling modulator 2
chr2_-_34138400 0.29 ENSDART00000056667
centromere protein L
chr21_-_31013817 0.29 ENSDART00000065504
nuclear cap binding subunit 3
chr1_+_19930520 0.29 ENSDART00000158344
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr9_+_12907574 0.29 ENSDART00000102348
si:dkey-230p4.1
chr19_-_18152942 0.29 ENSDART00000190182
nuclear factor, erythroid 2-like 3
chr17_-_50045375 0.29 ENSDART00000184639

chr6_-_27891961 0.28 ENSDART00000155116
im:7152348
chr17_+_23964132 0.28 ENSDART00000154823
exportin 1 (CRM1 homolog, yeast) b
chr3_-_30488063 0.28 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr19_+_627899 0.28 ENSDART00000148508
telomerase reverse transcriptase
chr19_-_7033636 0.28 ENSDART00000122815
ENSDART00000123443
ENSDART00000124094
death-domain associated protein
chr7_-_56831621 0.28 ENSDART00000182912
SUMO/sentrin peptidase family member, NEDD8 specific
chr23_-_33709964 0.28 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr8_+_3496204 0.28 ENSDART00000085993
paxillin b
chr13_-_7233811 0.27 ENSDART00000162026
ninein-like
chr21_-_11970199 0.27 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr7_+_1579510 0.27 ENSDART00000190525
SPT16 homolog, facilitates chromatin remodeling subunit
chr19_+_48102560 0.27 ENSDART00000164464
UTP18 small subunit (SSU) processome component
chr7_-_26518086 0.27 ENSDART00000058913
eukaryotic translation initiation factor 4A1A
chr25_+_126174 0.27 ENSDART00000168913
contactin 1a
chr17_-_43665366 0.27 ENSDART00000127945
early growth response 2a
chr19_+_43256986 0.27 ENSDART00000182336
diacylglycerol kinase delta
chr2_+_20868286 0.27 ENSDART00000062591
odr-4 GPCR localization factor homolog
chr8_-_27849770 0.27 ENSDART00000190196
ENSDART00000181244
CTTNBP2 N-terminal like b
chr16_-_31790285 0.26 ENSDART00000184655
chromodomain helicase DNA binding protein 4b
chr23_-_43424510 0.26 ENSDART00000055564
regulation of nuclear pre-mRNA domain containing 1B
chr9_-_1951144 0.26 ENSDART00000082355
homeobox D4a
chr9_+_27329640 0.26 ENSDART00000111039
si:rp71-84d19.3
chr6_-_19926657 0.26 ENSDART00000157527
ENSDART00000171384
netrin 1a
chr14_-_46259523 0.26 ENSDART00000172890
si:ch211-113d11.8
chr19_-_10971230 0.26 ENSDART00000166196

chr17_-_11357851 0.26 ENSDART00000153915
si:ch211-185a18.2
chr6_+_3717613 0.26 ENSDART00000184330
Sjogren syndrome antigen B (autoantigen La)
chr2_+_43920461 0.26 ENSDART00000123673
si:ch211-195h23.3
chr3_-_58165254 0.26 ENSDART00000093031
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr11_+_24046179 0.26 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr4_-_39171837 0.25 ENSDART00000179734
si:ch211-22k7.9
chr15_-_23442891 0.25 ENSDART00000059376
ubiquitination factor E4A (UFD2 homolog, yeast)
chr22_+_38978084 0.25 ENSDART00000025482
Rho guanine nucleotide exchange factor (GEF) 3
chr3_+_18846488 0.25 ENSDART00000148133
transmembrane protein 104
chr4_-_39111612 0.25 ENSDART00000150394
si:dkey-122c11.8
chr15_+_32798333 0.25 ENSDART00000162370
ENSDART00000166525
spartin b
chr25_+_22017182 0.25 ENSDART00000156517
si:dkey-217l24.1
chr16_+_53203370 0.25 ENSDART00000154669
si:ch211-269k10.2
chr14_-_38843690 0.25 ENSDART00000183629
spindle apparatus coiled-coil protein 1
chr3_-_16411244 0.25 ENSDART00000140067
elongation factor Tu GTP binding domain containing 2
chr24_+_37799818 0.24 ENSDART00000131975
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr23_-_23401305 0.24 ENSDART00000078936
hairy-related 9
chr5_+_56268436 0.24 ENSDART00000021159
LIM homeobox 1b
chr8_-_10961991 0.24 ENSDART00000139603
tripartite motif containing 33
chr25_+_31122806 0.24 ENSDART00000067039
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8a
chr4_-_33331681 0.24 ENSDART00000150319
zinc finger protein 1000
chr2_+_33326522 0.24 ENSDART00000056655
Kruppel-like factor 17
chr4_+_2655358 0.24 ENSDART00000007638
B cell receptor associated protein 29
chr5_+_53691803 0.24 ENSDART00000163256
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_-_4532066 0.24 ENSDART00000092687
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr5_+_31791001 0.24 ENSDART00000043010
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr9_+_17423941 0.23 ENSDART00000112884
ENSDART00000155233
kelch repeat and BTB (POZ) domain containing 7
chr2_-_24962820 0.23 ENSDART00000182767
helicase-like transcription factor
chr12_+_695619 0.23 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr4_+_22297839 0.23 ENSDART00000077707
LLP homolog, long-term synaptic facilitation (Aplysia)
chr21_+_17956856 0.23 ENSDART00000080431
dynein, axonemal, intermediate chain 1, paralog 2
chr15_+_2857556 0.23 ENSDART00000157758
MRE11 homolog A, double strand break repair nuclease
chr6_-_33916756 0.23 ENSDART00000137447
ENSDART00000138488
nuclear autoantigenic sperm protein (histone-binding)
chr12_-_30338779 0.23 ENSDART00000192511
von Willebrand factor A domain containing 2
chr4_-_77135076 0.23 ENSDART00000174184
zgc:173770
chr19_-_46018152 0.23 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr5_-_2672492 0.23 ENSDART00000192337

chr21_+_20391978 0.23 ENSDART00000180817
si:dkey-30k6.5
chr21_-_39058490 0.23 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr24_-_25461267 0.23 ENSDART00000105820
membrane-bound transcription factor peptidase, site 2
chr19_-_47997424 0.23 ENSDART00000081675
catenin, beta 2
chr18_-_12327426 0.22 ENSDART00000136992
ENSDART00000114024
family with sequence similarity 107, member B
chr20_-_13623882 0.22 ENSDART00000125218
ENSDART00000152499
synaptotagmin-like 3
chr6_+_35052721 0.22 ENSDART00000191090
ENSDART00000082940
U2AF homology motif (UHM) kinase 1
chr2_-_56387041 0.22 ENSDART00000036240
ceramide synthase 4b
chr5_-_39171302 0.22 ENSDART00000020808
progestin and adipoQ receptor family member IIIa
chr7_+_67749251 0.22 ENSDART00000167562
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr8_-_37101581 0.22 ENSDART00000185922
zgc:162200
chr9_+_20853894 0.22 ENSDART00000003648
WD repeat domain 3
chr23_+_16807209 0.22 ENSDART00000141966
zgc:114081
chr8_-_21988833 0.22 ENSDART00000167708
nephronophthisis 4
chr9_-_14143370 0.22 ENSDART00000108950
tubulin tyrosine ligase-like family, member 4
chr25_+_16356083 0.22 ENSDART00000125925
ENSDART00000125444
TEA domain family member 1a
chr11_-_34151487 0.22 ENSDART00000173039
ATPase 13A3
chr1_+_23784905 0.22 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit homolog 2 (Drosophila)
chr10_+_16092671 0.22 ENSDART00000182761
ENSDART00000154835
multiple EGF-like-domains 10
chr23_-_478201 0.22 ENSDART00000140749
si:ch73-181d5.4
chr23_-_21471022 0.22 ENSDART00000104206
hairy-related 4, tandem duplicate 2

Network of associatons between targets according to the STRING database.

First level regulatory network of cux2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.3 GO:0000012 single strand break repair(GO:0000012)
0.2 1.0 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.2 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.8 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.3 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.4 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.2 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.3 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 1.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.3 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.4 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.2 GO:0048785 hatching gland development(GO:0048785)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.2 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.1 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 1.5 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.2 GO:0071634 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.2 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.0 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.4 GO:0090342 regulation of cell aging(GO:0090342)
0.1 0.3 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.2 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.2 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.1 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.2 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.3 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.0 1.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.4 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0043703 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0001709 cell fate determination(GO:0001709)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.6 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.2 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.3 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.2 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.4 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.7 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070209 ASTRA complex(GO:0070209)
0.2 0.6 GO:0097268 cytoophidium(GO:0097268)
0.2 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0035101 FACT complex(GO:0035101)
0.1 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.2 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 0.6 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.1 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.4 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.0 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.2 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.2 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 1.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.0 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.2 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.0 GO:0001607 neuromedin U receptor activity(GO:0001607)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase