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PRJEB1986: zebrafish developmental stages transcriptome

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Results for cebpb

Z-value: 2.40

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Transcription factors associated with cebpb

Gene Symbol Gene ID Gene Info
ENSDARG00000042725 CCAAT enhancer binding protein beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpbdr11_v1_chr8_-_28449782_28449782-0.771.1e-04Click!

Activity profile of cebpb motif

Sorted Z-values of cebpb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_8606883 12.68 ENSDART00000054469
ENSDART00000185264
S100 calcium binding protein A10a
chr5_+_51079504 10.84 ENSDART00000097466
family with sequence similarity 169, member Aa
chr6_-_345503 10.70 ENSDART00000168901
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr5_-_33259079 9.93 ENSDART00000132223
interferon induced transmembrane protein 1
chr7_+_65240227 8.46 ENSDART00000168287
beta-carotene oxygenase 1, like
chr25_+_31222069 8.37 ENSDART00000159373
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr2_-_32643738 8.02 ENSDART00000112452
si:dkeyp-73d8.9
chr6_-_43449013 7.77 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr12_+_46960579 7.75 ENSDART00000149032
ornithine aminotransferase
chr20_-_40755614 6.92 ENSDART00000061247
connexin 32.3
chr25_-_30429607 6.83 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
chr21_-_40174647 6.67 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
solute carrier organic anion transporter family, member 2B1
chr5_-_30615901 6.64 ENSDART00000147769
si:ch211-117m20.5
chr2_-_30460293 6.62 ENSDART00000113193
cerebellin 2a precursor
chr5_-_58840971 6.38 ENSDART00000050932
transmembrane protein 136b
chr9_-_48736388 6.13 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr24_-_40009446 6.08 ENSDART00000087422
amine oxidase, copper containing 1
chr2_-_5356686 6.03 ENSDART00000124290
mitofusin 1
chr1_-_9231952 5.87 ENSDART00000166515
si:dkeyp-57d7.4
chr16_+_25245857 5.82 ENSDART00000155220
kelch-like family member 38b
chr7_+_49862837 5.79 ENSDART00000174315
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr9_-_34915351 5.78 ENSDART00000100728
ENSDART00000139608
UPF3A, regulator of nonsense mediated mRNA decay
chr7_-_34339845 5.54 ENSDART00000173816
MAP-kinase activating death domain
chr10_-_17103651 5.46 ENSDART00000108959
ring finger protein 208
chr22_+_17203752 5.44 ENSDART00000143376
RAB3B, member RAS oncogene family
chr23_-_26521970 5.38 ENSDART00000143712
si:dkey-205h13.1
chr14_-_46238186 5.37 ENSDART00000173245
si:ch211-113d11.6
chr21_-_43550120 5.27 ENSDART00000151627
si:ch73-362m14.2
chr14_+_16345003 5.16 ENSDART00000003040
ENSDART00000165193
intelectin 3
chr24_-_39771667 5.11 ENSDART00000181867
si:ch211-276f18.2
chr3_+_19299309 5.05 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr4_-_9549693 4.92 ENSDART00000160242

chr8_-_39739627 4.86 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr9_-_9989660 4.86 ENSDART00000081463
UDP glucuronosyltransferase 1 family a, b
chr20_+_1121458 4.81 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr4_+_12113105 4.72 ENSDART00000182399
transmembrane protein 178B
chr21_-_4032650 4.69 ENSDART00000151648
netrin g2b
chr12_+_35119762 4.68 ENSDART00000085774
si:ch73-127m5.1
chr2_-_31661609 4.63 ENSDART00000144383
si:ch211-106h4.9
chr15_-_1885247 4.60 ENSDART00000149703
P450 (cytochrome) oxidoreductase b
chr17_+_30450163 4.46 ENSDART00000104257
lipin 1
chr7_-_7845540 4.36 ENSDART00000166280
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr7_-_7823662 4.35 ENSDART00000167652
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr12_-_14922955 4.35 ENSDART00000002078
neurogenic differentiation 2
chr9_-_53062083 4.21 ENSDART00000122155
zmp:0000000936
chr16_-_27749172 4.19 ENSDART00000145198
STEAP family member 4
chr5_+_26795773 4.12 ENSDART00000145631
transcobalamin II
chr23_-_18030399 3.99 ENSDART00000136967
peptidase M20 domain containing 1, tandem duplicate 1
chr17_-_14613711 3.94 ENSDART00000157345
serine dehydratase-like
chr18_-_20869175 3.91 ENSDART00000090079
synemin, intermediate filament protein
chr13_+_40437550 3.86 ENSDART00000057090
ENSDART00000167859
glutamic-oxaloacetic transaminase 1, soluble
chr20_+_43113465 3.83 ENSDART00000004842
dual specificity phosphatase 23a
chr14_-_33613794 3.82 ENSDART00000010022
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr4_-_14915268 3.77 ENSDART00000067040
si:dkey-180p18.9
chr19_+_1370504 3.76 ENSDART00000158946
diacylglycerol O-acyltransferase 1a
chr17_+_30587333 3.74 ENSDART00000156500
NHS-like 1a
chr19_-_9829965 3.71 ENSDART00000136842
ENSDART00000142766
calcium channel, voltage-dependent, gamma subunit 8a
chr25_-_19443421 3.66 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr19_+_5674907 3.65 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr15_-_12258851 3.59 ENSDART00000180656
si:dkey-36i7.3
chr21_-_43949208 3.56 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr8_+_25351863 3.55 ENSDART00000034092
deoxyribonuclease I-like 1-like
chr14_-_12071447 3.50 ENSDART00000166116
thymosin beta 1
chr5_-_69948099 3.45 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr14_+_36885524 3.40 ENSDART00000032547
leukocyte cell-derived chemotaxin 2 like
chr9_+_219124 3.37 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr17_+_3124129 3.36 ENSDART00000155323
zgc:136872
chr6_+_8314451 3.34 ENSDART00000147793
ENSDART00000183688
glutaryl-CoA dehydrogenase a
chr11_-_6265574 3.32 ENSDART00000181974
ENSDART00000104405
chemokine (C-C motif) ligand 25b
chr13_-_20540790 3.32 ENSDART00000131467
si:ch1073-126c3.2
chr20_-_25533739 3.32 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr7_+_4162994 3.30 ENSDART00000172800
si:ch211-63p21.1
chr2_+_31476065 3.29 ENSDART00000049219
calcium channel, voltage-dependent, beta 2b
chr12_-_33706726 3.20 ENSDART00000153135
myosin XVB
chr25_+_20188769 3.19 ENSDART00000142781
caldesmon 1b
chr9_-_1702648 3.19 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr1_-_19237576 3.17 ENSDART00000143663
ENSDART00000131579
protein tyrosine phosphatase, receptor type, D, b
chr18_-_16179129 3.17 ENSDART00000125353
solute carrier family 6 (neutral amino acid transporter), member 15
chr14_-_5642371 3.16 ENSDART00000183859
ENSDART00000054876
nucleophosmin 1b
chr11_-_29082175 3.14 ENSDART00000123245
immunoglobin superfamily, member 21a
chr24_-_38644937 3.12 ENSDART00000170194
solute carrier family 6, member 16b
chr2_-_48966431 3.10 ENSDART00000147948
potassium inwardly-rectifying channel, subfamily J, member 9
chr18_+_15644559 3.10 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr17_-_45552602 3.08 ENSDART00000154844
ENSDART00000034432
sushi domain containing 4
chr12_-_45304971 3.06 ENSDART00000186537
ENSDART00000126405
ferredoxin reductase
chr13_+_7292061 3.02 ENSDART00000179504
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr21_-_5007109 3.02 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
ring finger protein 165a
chr11_-_2250767 3.01 ENSDART00000018131
heterogeneous nuclear ribonucleoprotein A1a
chr1_+_50538839 2.99 ENSDART00000020412
polycystic kidney disease 2
chr24_-_31123365 2.98 ENSDART00000182947
transmembrane protein 56a
chr18_-_14274803 2.95 ENSDART00000166643
malonyl-CoA decarboxylase
chr25_-_32869794 2.93 ENSDART00000162784
transmembrane protein 266
chr22_-_10487490 2.89 ENSDART00000064798
asporin (LRR class 1)
chr10_+_44940693 2.87 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr12_-_31012741 2.85 ENSDART00000145967
transcription factor 7 like 2
chr19_+_4990496 2.85 ENSDART00000151050
ENSDART00000017535
zgc:91968
chr7_+_11543999 2.79 ENSDART00000173676
interleukin 16
chr9_+_13682133 2.78 ENSDART00000175639
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr16_+_49601838 2.77 ENSDART00000168570
ENSDART00000159236
si:dkey-82o10.4
chr22_+_18469004 2.74 ENSDART00000061430
cartilage intermediate layer protein 2
chr14_-_7306983 2.73 ENSDART00000158914
si:ch211-51f19.1
chr23_-_36724575 2.72 ENSDART00000159560
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr16_+_25259313 2.72 ENSDART00000058938
F-box protein 32
chr16_+_47207691 2.72 ENSDART00000062507
islet cell autoantigen 1
chr17_-_15149192 2.71 ENSDART00000180511
ENSDART00000103405
GTP cyclohydrolase 1
chr1_-_19215336 2.70 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr7_-_4296771 2.65 ENSDART00000128855
cerebellin 11
chr15_-_4314042 2.64 ENSDART00000173311
ENSDART00000170562
si:ch211-117a13.2
chr22_-_18491813 2.64 ENSDART00000105419
si:ch211-212d10.2
chr13_+_13770980 2.61 ENSDART00000113089
solute carrier family 4, sodium borate transporter, member 11
chr14_+_7902374 2.61 ENSDART00000113299
zgc:110843
chr7_-_29723761 2.60 ENSDART00000173560
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr16_+_50289916 2.57 ENSDART00000168861
ENSDART00000167332
hepcidin antimicrobial peptide
chr17_-_6076084 2.56 ENSDART00000058890
epoxide hydrolase 2, cytoplasmic
chr22_-_16377666 2.55 ENSDART00000161878
tetratricopeptide repeat domain 39C
chr6_+_27151940 2.55 ENSDART00000088364
kinesin family member 1Aa
chr16_+_14029283 2.55 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr25_+_13191391 2.55 ENSDART00000109937
si:ch211-147m6.2
chr24_-_28381404 2.50 ENSDART00000148406
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr21_-_39058490 2.49 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr11_-_24681292 2.48 ENSDART00000089601
olfactomedin-like 3b
chr3_+_13637383 2.47 ENSDART00000166000
si:ch211-194b1.1
chr15_-_22139566 2.45 ENSDART00000149017
sodium channel, voltage-gated, type III, beta
chr15_+_45994123 2.44 ENSDART00000124704
leucine rich repeat and fibronectin type III domain containing 1
chr23_-_36003441 2.43 ENSDART00000164699
calcium binding and coiled-coil domain 1a
chr6_-_38816500 2.42 ENSDART00000190866
ENSDART00000104124
cyclic nucleotide gated channel alpha 3a
chr19_-_9662958 2.42 ENSDART00000041094
chloride channel, voltage-sensitive 1a
chr12_-_31457301 2.42 ENSDART00000043887
ENSDART00000148603
acyl-CoA synthetase long chain family member 5
chr12_+_16132612 2.41 ENSDART00000152550
low density lipoprotein receptor-related protein 2b
chr25_-_17239008 2.41 ENSDART00000151965
ENSDART00000152106
ENSDART00000152107
cyclin D2, a
chr23_+_44732863 2.40 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr19_+_7045033 2.37 ENSDART00000146579
major histocompatibility complex class I UKA
chr20_+_16743056 2.33 ENSDART00000050308
calmodulin 1b
chr2_+_11029138 2.32 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acyl-CoA thioesterase 11a
chr25_-_32311048 2.30 ENSDART00000181806
ENSDART00000086334

chr19_+_4990320 2.29 ENSDART00000147056
zgc:91968
chr18_+_507835 2.25 ENSDART00000189701
neural precursor cell expressed, developmentally down-regulated 4a
chr4_-_77432218 2.23 ENSDART00000158683
solute carrier organic anion transporter family, member 1D1
chr10_+_15255012 2.21 ENSDART00000023766
very low density lipoprotein receptor
chr8_+_28900689 2.20 ENSDART00000141634
glutamate receptor, ionotropic, delta 2
chr3_-_57744323 2.19 ENSDART00000101829
lectin, galactoside-binding, soluble, 3 binding protein b
chr9_-_4856767 2.16 ENSDART00000016814
ENSDART00000138015
formin-like 2a
chr19_-_9472893 2.14 ENSDART00000045565
ENSDART00000137505
vesicle-associated membrane protein 1
chr6_+_8315050 2.12 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr6_-_14292307 2.08 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr11_-_44931962 2.07 ENSDART00000170345
phosphofructokinase, liver b
chr24_-_15648636 2.05 ENSDART00000136200
cerebellin 2b precursor
chr17_-_6076266 2.04 ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr3_-_43821191 2.03 ENSDART00000186816
stannin
chr5_+_32162684 2.02 ENSDART00000134472
TAO kinase 3b
chr25_+_13191615 2.01 ENSDART00000168849
si:ch211-147m6.2
chr8_+_46386601 2.01 ENSDART00000129661
ENSDART00000084081
8-oxoguanine DNA glycosylase
chr3_+_22242269 2.00 ENSDART00000168970
sodium channel, voltage-gated, type IV, alpha, b
chr22_-_26175237 2.00 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr18_+_22287084 1.98 ENSDART00000151919
ENSDART00000181644
CCCTC-binding factor (zinc finger protein)
chr21_-_36972127 1.97 ENSDART00000100310
drebrin 1
chr19_+_22085925 1.96 ENSDART00000185636
ATPase phospholipid transporting 9B
chr1_+_14253118 1.96 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr10_+_15310811 1.95 ENSDART00000136239
potassium channel, subfamily V, member 2a
chr12_+_32073660 1.94 ENSDART00000153245
ENSDART00000153268
syntaxin binding protein 4
chr9_+_33154841 1.94 ENSDART00000132465
dopey family member 2
chr22_+_15438513 1.94 ENSDART00000010846
glypican 5b
chr23_-_24195723 1.93 ENSDART00000145489
anoctamin 11
chr17_+_443264 1.92 ENSDART00000159086
zgc:195050
chr23_+_2669 1.89 ENSDART00000011146
twist3
chr6_-_13498745 1.87 ENSDART00000027684
ENSDART00000189438
myosin light chain kinase b
chr2_-_36819624 1.87 ENSDART00000140844
SLIT and NTRK-like family, member 3b
chr24_+_26134029 1.87 ENSDART00000185134
teleost multiple tissue opsin b
chr8_+_16990120 1.85 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr1_+_55752593 1.84 ENSDART00000108838
ENSDART00000134770
trans-2,3-enoyl-CoA reductase b
chr10_+_15255198 1.83 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr23_-_33361425 1.81 ENSDART00000031638
solute carrier family 48 (heme transporter), member 1a
chr16_+_44298902 1.81 ENSDART00000114795
dihydropyrimidinase
chr5_+_8196264 1.81 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr12_-_46959990 1.80 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr7_+_16033923 1.80 ENSDART00000161669
ENSDART00000114062
inner mitochondrial membrane peptidase subunit 1
chr10_+_45248326 1.79 ENSDART00000159797
zinc finger, MIZ-type containing 2
chr13_-_31544365 1.79 ENSDART00000005670
dehydrogenase/reductase (SDR family) member 7
chr14_-_2322484 1.78 ENSDART00000167806
si:ch73-379j16.2
chr7_-_52842605 1.77 ENSDART00000083002
microtubule-associated protein 1Aa
chr22_+_15438872 1.77 ENSDART00000139800
glypican 5b
chr17_+_10501647 1.76 ENSDART00000140391
TYRO3 protein tyrosine kinase
chr15_-_29573267 1.76 ENSDART00000099947
SAM domain, SH3 domain and nuclear localisation signals 1a
chr21_-_22547496 1.75 ENSDART00000166835
ENSDART00000089030
myosin VB
chr5_-_55395384 1.75 ENSDART00000147298
ENSDART00000082577
prune homolog 2 (Drosophila)
chr17_-_43466317 1.74 ENSDART00000155313
heat shock protein 4 like
chr20_+_9211237 1.72 ENSDART00000139527
si:ch211-59d15.4
chr1_-_52222989 1.71 ENSDART00000010236
calponin 1, basic, smooth muscle, a
chr5_-_26181863 1.69 ENSDART00000098500
coiled-coil domain containing 125
chr17_-_27976031 1.68 ENSDART00000154829
platelet-activating factor receptor
chr22_+_26798853 1.65 ENSDART00000087576
ENSDART00000179780
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr22_-_26236188 1.64 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
complement component c3b, tandem duplicate 1
chr19_-_15192840 1.61 ENSDART00000151337
phosphatase and actin regulator 4a
chr25_+_13498188 1.59 ENSDART00000015710
SNF related kinase b
chr5_-_56412262 1.58 ENSDART00000083079
acetyl-CoA carboxylase alpha
chr24_-_17049270 1.58 ENSDART00000175508
methionine sulfoxide reductase B2
chr11_+_37251825 1.57 ENSDART00000169804
interleukin 17 receptor C
chr6_+_22068589 1.55 ENSDART00000151205
aldehyde dehydrogenase 1 family, member L1
chr5_+_19094153 1.54 ENSDART00000186525
ENSDART00000064752
unc-13 homolog Ba (C. elegans)
chr6_+_58915889 1.54 ENSDART00000083628
DNA-damage-inducible transcript 3

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
1.4 4.1 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
1.2 6.1 GO:0046677 response to antibiotic(GO:0046677)
1.1 3.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
1.1 4.3 GO:0060074 synapse maturation(GO:0060074)
1.1 6.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.0 4.2 GO:0015677 copper ion import(GO:0015677)
1.0 3.1 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
1.0 4.0 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.0 3.0 GO:0071498 cellular response to fluid shear stress(GO:0071498)
1.0 3.9 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
1.0 3.9 GO:0006531 aspartate metabolic process(GO:0006531)
0.9 8.5 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.9 8.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.9 4.5 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.8 5.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.8 2.4 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) positive regulation of lipid transport(GO:0032370) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.8 3.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.7 2.9 GO:0010226 response to lithium ion(GO:0010226)
0.7 5.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.7 2.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.6 2.5 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.6 5.8 GO:0042574 retinal metabolic process(GO:0042574)
0.6 2.8 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.5 1.5 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.5 2.9 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.5 2.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.5 6.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.5 1.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.4 1.7 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 1.7 GO:0061010 gall bladder development(GO:0061010)
0.4 1.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 2.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 5.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 2.6 GO:0032570 response to progesterone(GO:0032570)
0.4 3.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 4.4 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.3 3.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.3 1.3 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3 5.1 GO:0090382 phagosome maturation(GO:0090382)
0.3 4.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 1.4 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.3 2.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 2.6 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.3 2.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 1.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 1.0 GO:0014909 smooth muscle cell migration(GO:0014909)
0.2 8.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.2 1.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 3.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 3.6 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.2 1.8 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.2 3.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 2.1 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.8 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 0.9 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 1.0 GO:0006574 valine catabolic process(GO:0006574)
0.2 4.6 GO:0060841 venous blood vessel development(GO:0060841)
0.2 4.7 GO:0070831 basement membrane assembly(GO:0070831)
0.2 2.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 5.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 1.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 8.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 3.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 2.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2 1.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 1.7 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 0.5 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 2.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 5.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 2.2 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 1.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.2 GO:0098900 regulation of action potential(GO:0098900)
0.1 2.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 2.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 2.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 0.5 GO:0030091 protein repair(GO:0030091)
0.1 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 2.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 1.2 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 2.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 1.0 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.2 GO:0031638 zymogen activation(GO:0031638)
0.1 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 3.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.6 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 0.8 GO:0070293 renal absorption(GO:0070293)
0.1 2.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.1 3.6 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 0.5 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 0.3 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 2.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 4.5 GO:0042493 response to drug(GO:0042493)
0.1 2.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.2 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.1 0.6 GO:1901998 toxin transport(GO:1901998)
0.1 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 1.0 GO:0008354 germ cell migration(GO:0008354)
0.1 1.8 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 4.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 1.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 3.2 GO:0010842 retina layer formation(GO:0010842)
0.1 3.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 4.0 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.6 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 1.0 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.7 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.5 GO:0007602 phototransduction(GO:0007602)
0.0 1.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.7 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 2.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.6 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 2.1 GO:0003146 heart jogging(GO:0003146)
0.0 0.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 3.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 1.5 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 1.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 1.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.9 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 3.2 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.8 GO:0055088 lipid homeostasis(GO:0055088)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 1.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.2 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 3.4 GO:0009725 response to hormone(GO:0009725)
0.0 0.6 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0044316 cone cell pedicle(GO:0044316)
1.5 10.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.7 2.9 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.5 2.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 5.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4 1.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.3 GO:0035339 SPOTS complex(GO:0035339)
0.3 3.9 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.3 1.7 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 2.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 4.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 2.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 8.4 GO:0005861 troponin complex(GO:0005861)
0.2 2.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 4.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 7.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 2.7 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 4.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.4 GO:0043195 terminal bouton(GO:0043195)
0.1 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 9.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.9 GO:0030425 dendrite(GO:0030425)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 2.0 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 27.5 GO:0005615 extracellular space(GO:0005615)
0.0 3.9 GO:0010008 endosome membrane(GO:0010008)
0.0 13.6 GO:0045202 synapse(GO:0045202)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 3.1 GO:0043005 neuron projection(GO:0043005)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 2.1 GO:0030016 myofibril(GO:0030016)
0.0 1.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 13.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.7 GO:0005153 interleukin-8 receptor binding(GO:0005153)
2.3 9.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.5 4.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.4 5.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
1.2 6.1 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 4.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
1.0 4.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.0 3.9 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.9 8.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.9 7.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.8 4.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.8 10.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.8 3.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.8 6.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.7 2.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 2.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.6 3.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.6 2.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 6.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 3.1 GO:0032052 bile acid binding(GO:0032052)
0.5 4.1 GO:0031419 cobalamin binding(GO:0031419)
0.5 1.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.5 2.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.5 3.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 12.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 1.8 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.4 2.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 1.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.4 1.6 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.4 2.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.4 3.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.4 3.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 1.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.4 4.0 GO:0004046 aminoacylase activity(GO:0004046)
0.4 3.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 3.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 7.8 GO:0008483 transaminase activity(GO:0008483)
0.3 2.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 2.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 3.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 1.0 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.3 1.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 1.0 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 2.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 5.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.8 GO:0015232 heme transporter activity(GO:0015232)
0.2 5.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 0.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.9 GO:0070513 death domain binding(GO:0070513)
0.2 2.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 5.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.2 2.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 2.4 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 0.9 GO:0050699 WW domain binding(GO:0050699)
0.2 3.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.8 GO:0015288 porin activity(GO:0015288)
0.2 1.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.5 GO:0016208 AMP binding(GO:0016208)
0.1 8.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 2.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.1 GO:0034452 dynactin binding(GO:0034452)
0.1 4.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 4.6 GO:0017022 myosin binding(GO:0017022)
0.1 0.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 2.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 3.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 3.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 1.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 3.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.2 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.1 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.7 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 3.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.5 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 2.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 4.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0030552 cAMP binding(GO:0030552)
0.1 1.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 2.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 2.8 GO:0043022 ribosome binding(GO:0043022)
0.1 8.3 GO:0015293 symporter activity(GO:0015293)
0.1 0.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.5 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 2.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 3.2 GO:0042562 hormone binding(GO:0042562)
0.0 9.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 3.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 4.9 GO:0022832 voltage-gated channel activity(GO:0022832)
0.0 1.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 4.0 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 5.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 2.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 4.0 PID REELIN PATHWAY Reelin signaling pathway
0.2 5.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 3.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.8 PID FOXO PATHWAY FoxO family signaling
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 4.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 12.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.2 3.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.8 6.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.6 10.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 3.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 2.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 4.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 1.6 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 1.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 1.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 2.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 3.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 2.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 4.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 4.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones