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PRJEB1986: zebrafish developmental stages transcriptome

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Results for cdx1a+cdx1b

Z-value: 1.00

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Transcription factors associated with cdx1a+cdx1b

Gene Symbol Gene ID Gene Info
ENSDARG00000114554 caudal type homeobox 1a
ENSDARG00000116139 caudal type homeobox 1 b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cdx1bdr11_v1_chr21_-_43992027_43992027-0.885.1e-07Click!
cdx1adr11_v1_chr14_+_3287740_3287740-0.752.1e-04Click!

Activity profile of cdx1a+cdx1b motif

Sorted Z-values of cdx1a+cdx1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_25257022 2.22 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr20_-_29499363 2.18 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr19_-_47571456 2.16 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr3_-_15999501 2.13 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr7_-_17028015 2.10 ENSDART00000022441
developing brain homeobox 1a
chr12_-_13205854 1.94 ENSDART00000077829
pelota mRNA surveillance and ribosome rescue factor
chr19_+_1872794 1.92 ENSDART00000013217
small nuclear ribonucleoprotein D1 polypeptide
chr8_-_32803227 1.90 ENSDART00000110079
zgc:194839
chr11_-_25257045 1.89 ENSDART00000130477
snail family zinc finger 1a
chr25_-_29074064 1.85 ENSDART00000165603
AT rich interactive domain 3B (BRIGHT-like)
chr6_+_40629066 1.80 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr11_-_25257595 1.77 ENSDART00000123567
snail family zinc finger 1a
chr19_+_1873059 1.74 ENSDART00000145246
small nuclear ribonucleoprotein D1 polypeptide
chr9_-_48370645 1.70 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr10_-_10864331 1.67 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr1_-_53468160 1.64 ENSDART00000143349
zgc:66455
chr16_+_38940758 1.62 ENSDART00000102482
ENSDART00000136215
enhancer of yellow 2 homolog (Drosophila)
chr21_-_39024754 1.59 ENSDART00000056878
tnf receptor-associated factor 4b
chr23_-_43718067 1.57 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr17_-_51222510 1.56 ENSDART00000166687
presenilin 1
chr2_-_9744081 1.56 ENSDART00000097732
dishevelled segment polarity protein 3a
chr10_-_31563049 1.50 ENSDART00000023575
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr2_+_19777146 1.49 ENSDART00000038648
polypyrimidine tract binding protein 2b
chr23_+_31596441 1.44 ENSDART00000053534
TBP-like 1
chr19_-_10306910 1.44 ENSDART00000151684
U2 small nuclear RNA auxiliary factor 2b
chr12_+_13205955 1.42 ENSDART00000092906
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr13_+_11436130 1.40 ENSDART00000169895
zinc finger and BTB domain containing 18
chr15_+_834697 1.35 ENSDART00000154861
ENSDART00000160694
si:dkey-7i4.14
zgc:174573
chr5_-_40510397 1.34 ENSDART00000146237
ENSDART00000051065
follistatin a
chr3_+_60589157 1.34 ENSDART00000165367
methyltransferase like 23
chr17_+_43595692 1.33 ENSDART00000156271
cilia and flagella associated protein 99
chr23_+_44349252 1.33 ENSDART00000097644
eph receptor B4b
chr21_-_11970199 1.31 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr17_+_32343121 1.30 ENSDART00000156051
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr1_-_14506759 1.30 ENSDART00000057044
si:dkey-194g4.1
chr11_+_6116503 1.29 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr2_-_6115389 1.28 ENSDART00000134921
peroxiredoxin 1
chr23_+_36087219 1.27 ENSDART00000154825
homeobox C3a
chr14_+_14841685 1.27 ENSDART00000158291
ENSDART00000162039
stem-loop binding protein
chr9_+_32178374 1.26 ENSDART00000078576
coenzyme Q10B
chr1_+_41596099 1.25 ENSDART00000111367
si:dkey-56e3.3
chr24_-_3407507 1.25 ENSDART00000132648
NCK adaptor protein 1b
chr5_+_38662125 1.23 ENSDART00000136949
si:dkey-58f10.13
chr23_-_3758637 1.22 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr21_-_25416391 1.22 ENSDART00000114081
spermine synthase
chr24_+_39105051 1.22 ENSDART00000115297
MSS51 mitochondrial translational activator
chr19_+_27970292 1.21 ENSDART00000103887
ENSDART00000145549
mediator complex subunit 10
chr8_-_39822917 1.20 ENSDART00000067843
zgc:162025
chr5_-_69499486 1.19 ENSDART00000023983
ENSDART00000180293
phosphoserine aminotransferase 1
chr21_+_19070921 1.16 ENSDART00000029874
NK6 homeobox 1
chr19_+_19747430 1.16 ENSDART00000166129
homeobox A9a
chr9_+_22782027 1.14 ENSDART00000090816
replication timing regulatory factor 1
chr7_-_59589547 1.12 ENSDART00000008554
ENSDART00000101731
La ribonucleoprotein domain family, member 7
chr16_+_52966812 1.12 ENSDART00000148435
ENSDART00000049099
ENSDART00000150117
thyroid hormone receptor interactor 13
chr5_-_36597612 1.12 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr10_-_31562695 1.12 ENSDART00000186456
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr7_+_50766094 1.11 ENSDART00000165037
si:ch73-380l10.2
chr6_-_7107868 1.09 ENSDART00000171123
nonhomologous end-joining factor 1
chr22_+_10440991 1.08 ENSDART00000064805
centromere protein P
chr18_+_9171778 1.08 ENSDART00000101192
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr23_+_7379728 1.08 ENSDART00000012194
GATA binding protein 5
chr10_-_3332362 1.07 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr8_-_50888806 1.06 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr14_+_35369979 1.03 ENSDART00000144702
ENSDART00000169712
clathrin interactor 1a
chr10_-_21545091 1.02 ENSDART00000029122
ENSDART00000132207
zgc:165539
chr14_-_45604667 1.02 ENSDART00000167016
si:ch211-276i12.9
chr14_+_21754521 1.02 ENSDART00000111839
lysine (K)-specific demethylase 2Ab
chr7_-_48263516 1.01 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr24_-_24114217 1.01 ENSDART00000160578
zgc:112982
chr9_+_2041535 1.01 ENSDART00000093187
limb and neural patterns a
chr21_+_41468856 1.00 ENSDART00000161175
biorientation of chromosomes in cell division 1
chr16_+_29376751 1.00 ENSDART00000168856
ENSDART00000162502
ENSDART00000050535
ribosomal RNA adenine dimethylase domain containing 1
chr6_-_23002373 0.99 ENSDART00000037709
ENSDART00000170369
nucleolar protein 11
chr14_+_4276394 0.99 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr3_+_62161184 0.99 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr8_-_25033681 0.98 ENSDART00000003493
nuclear transcription factor Y, alpha, like
chr21_-_15929041 0.97 ENSDART00000080693
LIM homeobox 5
chr1_+_45663727 0.96 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trafficking protein particle complex 5
chr16_-_17586883 0.95 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr23_+_43718115 0.94 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr4_-_56898328 0.94 ENSDART00000169189
si:dkey-269o24.6
chr6_-_6976096 0.94 ENSDART00000151822
ENSDART00000039443
ENSDART00000177960
tubulin, alpha 8 like 4
chr10_-_44924289 0.92 ENSDART00000171267
tubulin, alpha 7 like
chr1_+_27808916 0.92 ENSDART00000102335
paraspeckle component 1
chr5_+_70155935 0.92 ENSDART00000165570
regulator of G protein signaling 3a
chr12_+_27022517 0.92 ENSDART00000152975
male-specific lethal 1 homolog b (Drosophila)
chr5_+_64856666 0.92 ENSDART00000050863
zgc:101858
chr14_+_34490445 0.91 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr12_-_33746111 0.90 ENSDART00000127203
lethal giant larvae homolog 2 (Drosophila)
chr23_-_24699400 0.89 ENSDART00000104031
stromal cell derived factor 4
chr16_+_42471455 0.89 ENSDART00000166640
si:ch211-215k15.5
chr22_+_2512154 0.89 ENSDART00000097363
zgc:173726
chr22_-_9930079 0.88 ENSDART00000131734
si:dkey-253d23.9
chr21_+_41468210 0.86 ENSDART00000192287
biorientation of chromosomes in cell division 1
chr2_+_23351454 0.85 ENSDART00000017034
ENSDART00000154645
ring finger protein 2
chr3_+_22442445 0.85 ENSDART00000190921
WNK lysine deficient protein kinase 4b
chr20_-_34670236 0.84 ENSDART00000033325
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr2_-_6115688 0.83 ENSDART00000081663
peroxiredoxin 1
chr10_+_15340768 0.82 ENSDART00000046274
ENSDART00000168909
trafficking protein particle complex 13
chr3_-_4501026 0.82 ENSDART00000163052
zgc:162198
chr14_-_2602445 0.81 ENSDART00000166910
eukaryotic translation termination factor 1a
chr4_-_5775507 0.80 ENSDART00000021753
cyclin C
chr5_-_31856681 0.79 ENSDART00000187817
protein kinase N3
chr5_-_1963498 0.79 ENSDART00000073462
ribosomal protein, large, P0
chr10_+_27068251 0.79 ENSDART00000012717
EH-domain containing 1b
chr2_-_32366287 0.78 ENSDART00000144758
upstream binding transcription factor, like
chr15_+_30323491 0.77 ENSDART00000048847
nitric oxide synthase 2b, inducible
chr19_-_17304866 0.77 ENSDART00000160433
ENSDART00000190798
ENSDART00000171284
splicing factor 3a, subunit 3
chr3_+_36646054 0.75 ENSDART00000170013
ENSDART00000159948
G1 to S phase transition 1, like
chr6_-_10728921 0.75 ENSDART00000151484
Sp3b transcription factor
chr20_-_43741159 0.75 ENSDART00000192621
si:dkeyp-50f7.2
chr2_+_19785540 0.74 ENSDART00000149789
polypyrimidine tract binding protein 2b
chr18_-_12295092 0.74 ENSDART00000033248
family with sequence similarity 107, member B
chr19_+_19652439 0.73 ENSDART00000165934
3-hydroxyisobutyrate dehydrogenase a
chr2_-_27975530 0.73 ENSDART00000020367
zgc:56556
chr6_-_37745508 0.71 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr1_+_46194333 0.71 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr23_+_36115541 0.70 ENSDART00000130090
homeobox C6a
chr24_+_5237753 0.70 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr10_-_34889053 0.69 ENSDART00000136966
coiled-coil domain containing 169
chr12_+_3871452 0.68 ENSDART00000066546
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr9_-_16853462 0.68 ENSDART00000160273

chr4_-_20135919 0.68 ENSDART00000172230
centrosomal protein 83
chr1_+_47178529 0.67 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
MORC family CW-type zinc finger 3b
chr2_+_23039041 0.67 ENSDART00000056921
casein kinase 1, gamma 2a
chr1_-_45752010 0.67 ENSDART00000101410
si:ch211-214c7.5
chr4_-_42014474 0.66 ENSDART00000193544
si:dkey-237m9.1
chr23_-_10722664 0.66 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
forkhead box P1a
chr22_+_2403068 0.66 ENSDART00000132925
ENSDART00000132569
zgc:112977
chr24_-_17029374 0.65 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr3_+_24190207 0.65 ENSDART00000034762
proline rich 15-like a
chr3_+_39579393 0.64 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr10_+_40321067 0.63 ENSDART00000109816
glycolipid transfer protein b
chr5_-_31857345 0.62 ENSDART00000112546
protein kinase N3
chr13_+_45431660 0.62 ENSDART00000099950
SYF2 pre-mRNA-splicing factor
chr22_+_21255860 0.62 ENSDART00000134893
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr2_+_26682913 0.62 ENSDART00000010683
ENSDART00000131411
ENSDART00000137933
inositol monophosphatase 1
chr22_-_25043103 0.61 ENSDART00000015512
polymerase (RNA) III (DNA directed) polypeptide F
chr8_+_25959940 0.60 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
chr7_+_18989241 0.59 ENSDART00000053213
zgc:194252
chr24_-_10014512 0.59 ENSDART00000124341
ENSDART00000191630
zgc:171474
chr19_+_3840955 0.59 ENSDART00000172305
LSM10, U7 small nuclear RNA associated
chr22_-_10605045 0.58 ENSDART00000184812
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr18_+_14684115 0.57 ENSDART00000108469
spermatogenesis associated 2-like
chr16_-_21915223 0.57 ENSDART00000170634
SET domain, bifurcated 1b
chr9_+_51891 0.57 ENSDART00000163529
zgc:158316
chr11_-_25461336 0.56 ENSDART00000014945
host cell factor C1a
chr16_-_9675982 0.56 ENSDART00000113724
mal, T cell differentiation protein 2 (gene/pseudogene)
chr16_-_25368048 0.56 ENSDART00000132445
ribosome binding factor A
chr11_-_18323059 0.56 ENSDART00000182590
Scm like with four mbt domains 1
chr23_-_39959173 0.56 ENSDART00000077122
chemokine (C motif) receptor 1a, duplicate 1
chr11_-_36051004 0.55 ENSDART00000025033
glutathione peroxidase 1a
chr11_-_44622478 0.54 ENSDART00000171837
tubulin folding cofactor E
chr17_-_30652738 0.54 ENSDART00000154960
SH3 and SYLF domain containing 1
chr18_-_14691727 0.54 ENSDART00000010129
peptide deformylase, mitochondrial
chr16_-_16225260 0.54 ENSDART00000165790
granulito
chr10_+_40629616 0.54 ENSDART00000147476

chr24_-_10006158 0.53 ENSDART00000106244
zgc:171750
chr10_+_26612321 0.53 ENSDART00000134322
four and a half LIM domains 1b
chr2_+_35733335 0.52 ENSDART00000113489
RAS protein activator like 2
chr5_+_50913034 0.52 ENSDART00000149787
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr14_+_15495088 0.51 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
chr7_+_52154215 0.50 ENSDART00000098712
zgc:77041
chr12_+_3262564 0.48 ENSDART00000184264
transmembrane protein 101
chr23_-_39959784 0.48 ENSDART00000115046
chemokine (C motif) receptor 1a, duplicate 1
chr3_-_53091946 0.48 ENSDART00000187297
lysophosphatidic acid receptor 2a
chr21_+_25236297 0.48 ENSDART00000112783
transmembrane protein 45B
chr5_+_58687541 0.47 ENSDART00000083015
ENSDART00000181902
coiled-coil domain containing 84
chr11_+_44622472 0.47 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
RNA binding motif protein 34
chr15_+_42285643 0.46 ENSDART00000152731
SR-related CTD-associated factor 4b
chr2_+_16798923 0.46 ENSDART00000181603
ENSDART00000179816
ENSDART00000087107
ENSDART00000187009
eukaryotic translation initiation factor 4 gamma, 1a
chr1_+_8508753 0.45 ENSDART00000091683
alkB homolog 5, RNA demethylase
chr22_-_10440688 0.44 ENSDART00000111962
nucleolar protein 8
chr17_-_43666166 0.44 ENSDART00000077990
early growth response 2a
chr25_+_9013342 0.44 ENSDART00000154207
ENSDART00000153705
im:7145024
chr20_-_13140309 0.43 ENSDART00000020703
ENSDART00000188594
integrator complex subunit 7
chr21_+_20396858 0.42 ENSDART00000003299
ENSDART00000146615
zgc:103482
chr23_+_309099 0.42 ENSDART00000134556
ENSDART00000055152
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_+_8481660 0.41 ENSDART00000109559

chr2_-_37458527 0.40 ENSDART00000146820
si:dkey-57k2.7
chr24_-_9997948 0.40 ENSDART00000136274
si:ch211-146l10.7
chr20_+_27087539 0.40 ENSDART00000062094
transmembrane protein 251
chr14_-_15171435 0.40 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr13_+_18520738 0.40 ENSDART00000113952
toll-like receptor 4a, like
chr1_-_7603734 0.40 ENSDART00000009315
myxovirus (influenza) resistance B
chr1_-_9486214 0.39 ENSDART00000137821
mical-like 2b
chr21_-_30181732 0.39 ENSDART00000015636
heterogeneous nuclear ribonucleoprotein H1, like
chr5_-_12713920 0.38 ENSDART00000099749
si:dkey-98f17.3
chr16_+_34046733 0.38 ENSDART00000058424
family with sequence similarity 46, member Ba
chr4_+_25630555 0.38 ENSDART00000133425
acyl-CoA thioesterase 15
chr12_-_31726748 0.37 ENSDART00000153174
serine/arginine-rich splicing factor 2a
chr16_-_27138478 0.36 ENSDART00000147438
transmembrane protein 245
chr2_+_19522082 0.36 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr6_+_49551614 0.36 ENSDART00000022581
RAB22A, member RAS oncogene family
chr15_+_9297340 0.36 ENSDART00000055554
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr3_-_4557653 0.36 ENSDART00000111305
finTRIM family, member 50
chr2_+_31948352 0.36 ENSDART00000192611
ANKH inorganic pyrophosphate transport regulator b
chr16_+_43344475 0.36 ENSDART00000085282
mitochondrial ribosomal protein L32
chr14_+_22447662 0.35 ENSDART00000161776
sosondowah ankyrin repeat domain family member Ab
chr5_-_24997293 0.35 ENSDART00000177478
EMI domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of cdx1a+cdx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0032790 ribosome disassembly(GO:0032790)
0.4 1.2 GO:1905072 cardiac jelly development(GO:1905072)
0.4 1.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 1.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 4.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 1.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.4 1.1 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 2.1 GO:0097065 anterior head development(GO:0097065)
0.3 1.0 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 1.0 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 1.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.3 1.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.3 1.0 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.2 2.2 GO:0016578 histone deubiquitination(GO:0016578)
0.2 1.0 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 1.6 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.1 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.2 2.1 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 2.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 0.9 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 0.9 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 1.1 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 3.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 0.5 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.2 0.8 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 1.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 2.1 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.8 GO:0031284 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.7 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 3.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.6 GO:0045056 transcytosis(GO:0045056)
0.1 1.9 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 1.0 GO:0045682 regulation of epidermis development(GO:0045682)
0.1 0.6 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.6 GO:0015809 arginine transport(GO:0015809)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 2.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0060958 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.1 1.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.9 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.2 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.0 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.6 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.0 GO:0000154 rRNA modification(GO:0000154)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 2.1 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.9 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.8 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 1.1 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.4 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.1 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 3.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.8 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.3 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.3 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 2.8 GO:0008380 RNA splicing(GO:0008380)
0.0 0.5 GO:0036269 swimming behavior(GO:0036269)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.5 3.7 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.3 1.6 GO:0070390 transcription export complex 2(GO:0070390)
0.3 1.6 GO:0018444 translation release factor complex(GO:0018444)
0.3 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.3 0.9 GO:0097189 apoptotic body(GO:0097189)
0.2 1.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 1.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 0.5 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.2 1.4 GO:0089701 U2AF(GO:0089701)
0.1 1.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0072487 MSL complex(GO:0072487)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.6 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 2.5 GO:0016605 PML body(GO:0016605)
0.1 1.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 3.0 GO:0016592 mediator complex(GO:0016592)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.7 GO:0005938 cell cortex(GO:0005938)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.6 4.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 1.0 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 2.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.6 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.7 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.6 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.5 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 1.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 2.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 1.3 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 2.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 2.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.1 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.2 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 1.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 1.6 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 3.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)