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PRJEB1986: zebrafish developmental stages transcriptome

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Results for cdc5l

Z-value: 2.46

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Transcription factors associated with cdc5l

Gene Symbol Gene ID Gene Info
ENSDARG00000043797 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cdc5ldr11_v1_chr17_+_5061135_50611350.821.6e-05Click!

Activity profile of cdc5l motif

Sorted Z-values of cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_29509133 7.20 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr5_-_61652254 6.83 ENSDART00000097364
draculin
chr5_+_50879545 5.90 ENSDART00000128402
nucleolar protein 6 (RNA-associated)
chr21_-_44512893 5.90 ENSDART00000166853
zgc:136410
chr11_+_41981959 5.55 ENSDART00000055707
hairy and enhancer of split-related 15, tandem duplicate 1
chr7_+_24881680 5.49 ENSDART00000058843
kelch repeat-containing protein
chr20_-_26491567 5.42 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr8_-_16725573 5.36 ENSDART00000049676
DEP domain containing 1a
chr9_+_34397516 5.14 ENSDART00000011304
ENSDART00000192973
mediator complex subunit 14
chr4_+_35553514 4.96 ENSDART00000182938

chr20_-_38801981 4.66 ENSDART00000125333
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr7_-_17337233 4.61 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr5_-_61624693 4.47 ENSDART00000141323
si:dkey-261j4.4
chr2_-_42958619 4.47 ENSDART00000144317
otoconin 90
chr3_+_6443992 4.36 ENSDART00000169325
ENSDART00000162255
nucleoporin 85
chr17_+_5985933 4.13 ENSDART00000190844
zgc:194275
chr19_+_27859546 4.10 ENSDART00000161908
NOP2/Sun RNA methyltransferase family, member 2
chr11_-_6880725 3.87 ENSDART00000007204
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr2_-_42960353 3.84 ENSDART00000098303
otoconin 90
chr16_-_25699554 3.83 ENSDART00000155899
ENSDART00000114495
DEAD (Asp-Glu-Ala-Asp) box helicase 61
chr1_-_11104805 3.79 ENSDART00000147648
kinetochore scaffold 1
chr6_-_8377055 3.78 ENSDART00000131513
interleukin enhancer binding factor 3a
chr22_-_16291041 3.74 ENSDART00000021666
RNA 3'-terminal phosphate cyclase
chr9_-_27398369 3.72 ENSDART00000186499
testis expressed 30
chr2_-_19234329 3.67 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cell division cycle 20 homolog
chr15_-_16333015 3.67 ENSDART00000080892
thioredoxin domain containing 17
chr9_+_34397843 3.64 ENSDART00000146314
mediator complex subunit 14
chr19_-_13933204 3.64 ENSDART00000158059
tRNA selenocysteine 1 associated protein 1a
chr6_+_60125033 3.61 ENSDART00000148557
ENSDART00000008224
aurora kinase A
chr23_-_23179417 3.53 ENSDART00000122945
ENSDART00000091662
NOC2-like nucleolar associated transcriptional repressor
chr23_+_32011768 3.52 ENSDART00000053509
pleiomorphic adenoma gene X
chr7_-_20464133 3.46 ENSDART00000078192
canopy4
chr17_-_31695217 3.31 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr4_-_11580948 3.31 ENSDART00000049066
neuroepithelial cell transforming 1
chr3_+_23697997 3.29 ENSDART00000184299
ENSDART00000078466
homeobox B3a
chr17_-_14700889 3.28 ENSDART00000179975
protein tyrosine phosphatase type IVA, member 2a
chr21_+_20901505 3.23 ENSDART00000132741
complement component 7b
chr4_-_71110826 3.23 ENSDART00000167431
si:dkeyp-80d11.1
chr14_-_30905963 3.22 ENSDART00000183543
ENSDART00000186441
si:ch211-126c2.4
chr24_+_22485710 3.21 ENSDART00000146058
si:dkey-40h20.1
chr13_-_37474989 3.21 ENSDART00000114136
WD repeat domain 89
chr2_+_2168547 3.19 ENSDART00000029347
HIG1 hypoxia inducible domain family, member 1A
chr9_-_21976670 3.17 ENSDART00000104322
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr9_+_44994214 3.16 ENSDART00000141434
retinol saturase (all-trans-retinol 13,14-reductase) like
chr13_+_18321140 3.16 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr11_-_33868881 3.12 ENSDART00000163295
ENSDART00000172633
ENSDART00000171439
si:ch211-227n13.3
chr21_-_22357545 3.11 ENSDART00000134320
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_-_38171648 3.09 ENSDART00000137451
ENSDART00000047159
high mobility group box 2a
chr6_+_29386728 3.08 ENSDART00000104303
actin-like 6A
chr16_-_12060770 3.07 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
chr8_+_45003659 3.06 ENSDART00000132663
si:ch211-163b2.4
chr7_-_24994568 3.06 ENSDART00000002961
REST corepressor 2
chr12_+_1609563 3.04 ENSDART00000163559
solute carrier family 39 member 11
chr4_+_17642731 3.04 ENSDART00000026509
CWF19-like 1, cell cycle control
chr21_-_29990574 3.03 ENSDART00000185800
si:ch73-190f9.4
chr15_-_14038227 3.02 ENSDART00000139068
zgc:114130
chr24_-_3426620 3.00 ENSDART00000184346
NCK adaptor protein 1b
chr5_+_45007962 2.99 ENSDART00000010786
doublesex and mab-3 related transcription factor 2a
chr4_-_56068511 2.99 ENSDART00000168345
zinc finger protein 1133
chr25_+_19557628 2.96 ENSDART00000133859
LYR motif containing 5b
chr2_-_23390779 2.96 ENSDART00000020136
influenza virus NS1A binding protein b
chr16_+_55059026 2.91 ENSDART00000109391
Danio rerio nuclear receptor coactivator 7-like (LOC792958), mRNA.
chr21_-_29533723 2.91 ENSDART00000193554

chr19_+_16064439 2.89 ENSDART00000151169
glucocorticoid modulatory element binding protein 1
chr22_+_8313513 2.88 ENSDART00000181169
ENSDART00000103911

chr4_+_18441988 2.87 ENSDART00000040827
non-SMC condensin II complex, subunit H2
chr19_-_3056235 2.87 ENSDART00000137020
block of proliferation 1
chr16_-_12060488 2.85 ENSDART00000188733
si:ch211-69g19.2
chr17_-_24937879 2.84 ENSDART00000153964

chr2_-_2813259 2.84 ENSDART00000032540
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr18_-_18874921 2.84 ENSDART00000193332
ADP-ribosylation factor-like 2 binding protein
chr22_+_1911269 2.82 ENSDART00000164158
ENSDART00000168205
zinc finger protein 1156
chr24_-_9294134 2.82 ENSDART00000082434
TGFB-induced factor homeobox 1
chr13_+_33606739 2.82 ENSDART00000026464
cofilin 1 (non-muscle), like
chr25_-_3217115 2.79 ENSDART00000032390
general transcription factor IIH, polypeptide 1
chr14_+_22132388 2.79 ENSDART00000109065
cyclin G1
chr7_-_20464468 2.79 ENSDART00000134700
canopy4
chr7_-_24994722 2.78 ENSDART00000131671
REST corepressor 2
chr20_+_28803642 2.78 ENSDART00000188526
farnesyltransferase, CAAX box, beta
chr20_+_43691208 2.77 ENSDART00000152976
ENSDART00000045185
lin-9 DREAM MuvB core complex component
chr10_+_22918338 2.76 ENSDART00000167874
ENSDART00000171298
zgc:103508
chr17_-_8312923 2.75 ENSDART00000064678
lefty2
chr20_-_27225876 2.75 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
chr1_-_53880639 2.72 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr24_-_31904924 2.71 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr19_+_636886 2.69 ENSDART00000149192
telomerase reverse transcriptase
chr9_-_32300783 2.66 ENSDART00000078596
heat shock 60 protein 1
chr21_-_29735366 2.65 ENSDART00000181668

chr9_+_30090656 2.65 ENSDART00000102981
collagen, type VIII, alpha 1a
chr8_+_22355909 2.64 ENSDART00000146457
ENSDART00000142883
zgc:153631
chr21_-_29689141 2.64 ENSDART00000100876

chr19_+_15444210 2.63 ENSDART00000142509
lin-28 homolog A (C. elegans)
chr21_-_19919020 2.63 ENSDART00000147396
protein phosphatase 1, regulatory subunit 3B
chr5_+_33289057 2.61 ENSDART00000123210
mediator complex subunit 22
chr6_-_30683637 2.59 ENSDART00000065212
tetratricopeptide repeat domain 4
chr19_-_8536474 2.57 ENSDART00000139715
dolichyl-phosphate mannosyltransferase polypeptide 3
chr16_-_33650578 2.57 ENSDART00000058460
UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
chr4_+_23127284 2.54 ENSDART00000122675
MDM2 oncogene, E3 ubiquitin protein ligase
chr6_-_19340889 2.52 ENSDART00000181407
MIF4G domain containing a
chr6_-_29402578 2.51 ENSDART00000115031
mitochondrial ribosomal protein L47
chr10_+_13209580 2.51 ENSDART00000000887
ENSDART00000136932
Ras association (RalGDS/AF-6) domain family 6
chr14_+_36220479 2.50 ENSDART00000148319
paired-like homeodomain 2
chr4_+_64562090 2.50 ENSDART00000188810
si:ch211-223a21.3
chr9_-_41040098 2.49 ENSDART00000008275
adenosine deaminase, tRNA-specific 3
chr5_+_45008418 2.47 ENSDART00000189882
doublesex and mab-3 related transcription factor 2a
chr2_+_50967947 2.46 ENSDART00000162288
si:ch211-249o11.5
chr7_-_26844064 2.46 ENSDART00000162241
si:ch211-107p11.3
chr3_-_54607166 2.46 ENSDART00000021977
DNA (cytosine-5-)-methyltransferase 1
chr13_+_30912117 2.44 ENSDART00000133138
dorsal root ganglia homeobox
chr6_-_41091151 2.43 ENSDART00000154963
ENSDART00000153818
serine/arginine-rich splicing factor 3a
chr18_-_18875308 2.41 ENSDART00000127182
ADP-ribosylation factor-like 2 binding protein
chr24_-_38657683 2.41 ENSDART00000154843
si:ch1073-164k15.3
chr9_-_32300611 2.41 ENSDART00000127938
heat shock 60 protein 1
chr7_-_28647959 2.39 ENSDART00000150148
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr18_+_6536598 2.38 ENSDART00000149350
FK506 binding protein 4
chr2_-_10877228 2.38 ENSDART00000138718
ENSDART00000034246
cell division cycle 7 homolog (S. cerevisiae)
chr21_-_29477624 2.35 ENSDART00000180110

chr3_-_42125655 2.34 ENSDART00000040753
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr20_+_26394324 2.32 ENSDART00000078093
zinc finger and BTB domain containing 2b
chr2_-_9607879 2.30 ENSDART00000056899
thioredoxin domain containing 12 (endoplasmic reticulum)
chr12_-_13336703 2.30 ENSDART00000134356
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr1_-_30762264 2.28 ENSDART00000085454
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
chr6_-_52234796 2.26 ENSDART00000001803
translocase of outer mitochondrial membrane 34
chr18_+_6536293 2.25 ENSDART00000024576
FK506 binding protein 4
chr13_-_42757565 2.24 ENSDART00000161950
calpain 2, (m/II) large subunit a
chr10_+_16036246 2.24 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lamin B1
chr5_+_60847823 2.24 ENSDART00000074426
ligase III, DNA, ATP-dependent
chr24_+_22022109 2.24 ENSDART00000133686
rhophilin associated tail protein 1-like
chr16_+_29690708 2.23 ENSDART00000103054
LysM, putative peptidoglycan-binding, domain containing 1
chr23_-_29553430 2.22 ENSDART00000157773
ENSDART00000126384
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr9_+_21259820 2.22 ENSDART00000137024
ENSDART00000132324
spindle and kinetochore associated complex subunit 3
chr11_-_36350421 2.22 ENSDART00000141477
proteasome subunit alpha 5
chr8_-_16697912 2.21 ENSDART00000076542
retinal pigment epithelium-specific protein 65b
chr21_-_29940453 2.21 ENSDART00000182862

chr17_-_36529449 2.20 ENSDART00000187252
collectin sub-family member 11
chr19_+_20163826 2.20 ENSDART00000090942
ENSDART00000134650
coiled-coil domain containing 126
chr19_+_3206263 2.19 ENSDART00000020344
zgc:86598
chr25_+_5249513 2.19 ENSDART00000126814

chr4_-_29769304 2.19 ENSDART00000134990
zinc finger protein 1119
chr3_-_24681404 2.18 ENSDART00000161612

chr6_-_19341184 2.18 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr15_-_41689981 2.17 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr23_-_3409140 2.17 ENSDART00000002309
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr18_+_17537975 2.17 ENSDART00000179783
nucleoporin 93
chr4_-_76488854 2.16 ENSDART00000132323
finTRIM family, member 51
chr5_-_41645058 2.16 ENSDART00000051092
RIO kinase 2 (yeast)
chr10_+_16036573 2.16 ENSDART00000188757
lamin B1
chr19_-_27588842 2.15 ENSDART00000121643
si:dkeyp-46h3.2
chr4_+_69863750 2.15 ENSDART00000170800
zinc finger protein 1117
chr2_-_57264262 2.15 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
methyl-CpG binding domain protein 3a
chr4_+_29532731 2.13 ENSDART00000114649
zinc finger protein 1140
chr10_+_39893439 2.12 ENSDART00000003435
small fragment nuclease
chr22_-_15593824 2.12 ENSDART00000123125
tropomyosin 4a
chr6_-_37745508 2.11 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr12_-_9533956 2.10 ENSDART00000188940
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr10_+_21434649 2.10 ENSDART00000193938
ENSDART00000064558
eukaryotic translation termination factor 1b
chr14_-_38826739 2.07 ENSDART00000187633
spindle apparatus coiled-coil protein 1
chr18_-_48296793 2.07 ENSDART00000032184
ENSDART00000193076

chr19_-_27578929 2.07 ENSDART00000177368
si:dkeyp-46h3.3
chr11_-_16152400 2.06 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr25_-_15040369 2.06 ENSDART00000159342
ENSDART00000166490
paired box 6a
chr4_+_1761029 2.05 ENSDART00000026963
peptidase (mitochondrial processing) beta
chr12_+_6065661 2.05 ENSDART00000142418
sphingomyelin synthase 1
chr15_-_20024205 2.04 ENSDART00000161379
autism susceptibility candidate 2b
chr2_-_32666174 2.04 ENSDART00000133660
poly-U binding splicing factor a
chr20_-_25645150 2.04 ENSDART00000063137
si:dkeyp-117h8.4
chr3_+_62161184 2.03 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr11_+_24994705 2.03 ENSDART00000129211
zgc:92107
chr3_-_61375496 2.02 ENSDART00000165188
si:dkey-111k8.2
chr18_-_17087138 2.01 ENSDART00000135597
zinc finger CCCH-type containing 18
chr14_+_22132896 1.99 ENSDART00000138274
cyclin G1
chr11_+_16152316 1.99 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr23_-_29553691 1.99 ENSDART00000053804
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr7_+_39664055 1.99 ENSDART00000146171
zgc:158564
chr2_-_22530969 1.98 ENSDART00000159641
zinc finger protein 644a
chr3_+_32651697 1.98 ENSDART00000055338
THO complex 6
chr2_+_52049239 1.97 ENSDART00000036813
coiled-coil domain containing 94
chr1_+_34695373 1.97 ENSDART00000077744
ENSDART00000102118
ENSDART00000135528
general transcription factor IIF, polypeptide 2a
chr8_-_28274251 1.96 ENSDART00000050671
RAP1A, member of RAS oncogene family a
chr6_+_43426599 1.96 ENSDART00000056457
microphthalmia-associated transcription factor a
chr4_+_30454496 1.94 ENSDART00000164555
si:dkey-199m13.4
chr9_+_29430432 1.94 ENSDART00000125632
UDP-glucose glycoprotein glucosyltransferase 2
chr11_+_1533097 1.93 ENSDART00000066191
intraflagellar transport 52 homolog (Chlamydomonas)
chr11_-_16395956 1.92 ENSDART00000115085
leucine-rich repeats and immunoglobulin-like domains 1
chr17_-_19463355 1.92 ENSDART00000045881
dicer 1, ribonuclease type III
chr4_-_77260727 1.91 ENSDART00000075770
zgc:162948
chr17_-_36529016 1.91 ENSDART00000025019
collectin sub-family member 11
chr25_+_17925424 1.90 ENSDART00000067305
zgc:103499
chr6_+_3716666 1.90 ENSDART00000041627
Sjogren syndrome antigen B (autoantigen La)
chr12_+_5708400 1.89 ENSDART00000017191
distal-less homeobox 3b
chr18_+_14633974 1.89 ENSDART00000133834
VPS9 domain containing 1
chr11_+_24815667 1.88 ENSDART00000141730
RAB interacting factor
chr7_-_8315179 1.88 ENSDART00000184049
coagulation factor XIII, A1 polypeptide b
chr4_+_33225161 1.87 ENSDART00000150851
si:dkey-247i3.5
chr23_-_13295923 1.87 ENSDART00000189214
ENSDART00000165432
Danio rerio uncharacterized LOC100001444 (LOC100001444), mRNA.
chr13_+_22555342 1.87 ENSDART00000193633
bone morphogenetic protein receptor, type IAa
chr5_+_18047111 1.87 ENSDART00000132164
histone cell cycle regulator a
chr17_-_15189397 1.85 ENSDART00000133710
ENSDART00000110507
WD repeat and HMG-box DNA binding protein 1
chr2_+_2169337 1.85 ENSDART00000179939
HIG1 hypoxia inducible domain family, member 1A
chr4_+_45504471 1.84 ENSDART00000150399
si:dkey-256i11.2

Network of associatons between targets according to the STRING database.

First level regulatory network of cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.6 4.7 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.5 4.6 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
1.3 5.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
1.2 3.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.9 1.9 GO:0021559 trigeminal nerve development(GO:0021559)
0.9 2.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.9 2.7 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.9 2.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.8 5.0 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.7 2.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.7 2.2 GO:0021742 abducens nucleus development(GO:0021742)
0.7 2.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.7 2.8 GO:0018343 protein farnesylation(GO:0018343)
0.7 1.4 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.7 9.1 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.6 1.9 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.6 1.9 GO:0060912 cardiac cell fate specification(GO:0060912)
0.6 3.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.6 5.9 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.6 1.7 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.6 2.2 GO:0016117 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.5 1.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.5 3.3 GO:0032447 protein urmylation(GO:0032447)
0.5 1.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.5 3.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.5 1.6 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.5 2.5 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.5 6.6 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.5 1.5 GO:0048785 hatching gland development(GO:0048785)
0.5 2.5 GO:0061072 iris morphogenesis(GO:0061072)
0.5 2.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.5 2.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.5 3.8 GO:0034063 stress granule assembly(GO:0034063)
0.5 1.4 GO:0015695 organic cation transport(GO:0015695)
0.5 2.3 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.5 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 1.3 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.4 1.3 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.4 2.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.4 1.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 2.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 0.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.4 1.7 GO:0000338 protein deneddylation(GO:0000338)
0.4 1.6 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.4 1.6 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.4 2.0 GO:0071320 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 1.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.4 4.1 GO:0019730 antimicrobial humoral response(GO:0019730)
0.4 1.1 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.4 5.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.4 1.4 GO:0042148 strand invasion(GO:0042148)
0.4 3.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.4 2.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.4 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.0 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.3 2.3 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.3 1.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.3 1.0 GO:0065001 specification of axis polarity(GO:0065001)
0.3 0.9 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3 2.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.8 GO:1902946 protein localization to early endosome(GO:1902946)
0.3 2.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.3 8.8 GO:0019827 stem cell population maintenance(GO:0019827)
0.3 2.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 2.7 GO:0070475 rRNA base methylation(GO:0070475)
0.3 0.8 GO:0046133 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.3 2.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 1.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 1.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 2.0 GO:0036372 opsin transport(GO:0036372)
0.2 2.7 GO:0014028 notochord formation(GO:0014028)
0.2 0.7 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.2 0.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 0.2 GO:0051031 tRNA transport(GO:0051031)
0.2 2.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.2 1.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 0.7 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 2.6 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.2 3.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 1.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 1.5 GO:0034389 lipid particle organization(GO:0034389)
0.2 2.2 GO:0030719 P granule organization(GO:0030719)
0.2 2.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 5.1 GO:0043967 histone H4 acetylation(GO:0043967)
0.2 2.1 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.2 0.8 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 1.7 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 1.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 2.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 3.3 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.2 1.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 1.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 0.4 GO:0021588 cerebellum formation(GO:0021588)
0.2 0.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 2.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.2 1.7 GO:0006611 protein export from nucleus(GO:0006611)
0.2 6.2 GO:0007548 sex differentiation(GO:0007548)
0.2 4.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 5.6 GO:0032543 mitochondrial translation(GO:0032543)
0.2 0.5 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 5.2 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 1.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.2 5.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 3.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 2.9 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 1.8 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.8 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 1.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.7 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.2 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 1.5 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 2.8 GO:0003128 heart field specification(GO:0003128)
0.1 0.7 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 7.6 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.7 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 1.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 4.1 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.9 GO:0051279 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.1 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.6 GO:0016180 snRNA processing(GO:0016180)
0.1 1.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.5 GO:0045161 neuronal ion channel clustering(GO:0045161) clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.1 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.7 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.1 2.6 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 1.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 1.6 GO:0060324 face development(GO:0060324)
0.1 3.1 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 0.8 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 2.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 7.9 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 0.9 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 1.8 GO:0007286 spermatid development(GO:0007286)
0.1 0.5 GO:0016074 snoRNA metabolic process(GO:0016074)
0.1 0.4 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 7.1 GO:0006413 translational initiation(GO:0006413)
0.1 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 6.0 GO:0008033 tRNA processing(GO:0008033)
0.1 1.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.5 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 1.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 5.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 1.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.0 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.9 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.6 GO:0006857 oligopeptide transport(GO:0006857)
0.1 2.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.2 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.1 3.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 0.5 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 3.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 4.4 GO:0051607 defense response to virus(GO:0051607)
0.1 8.4 GO:0016072 rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.1 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.8 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 3.4 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.8 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551) regulation of phospholipid metabolic process(GO:1903725)
0.1 7.2 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.9 GO:0030878 thyroid gland development(GO:0030878)
0.1 2.0 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 2.7 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.1 0.6 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.8 GO:0035518 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 2.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 2.0 GO:0051028 mRNA transport(GO:0051028)
0.0 4.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 1.1 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 4.4 GO:0001756 somitogenesis(GO:0001756)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.8 GO:0042744 oxygen transport(GO:0015671) hydrogen peroxide catabolic process(GO:0042744)
0.0 3.0 GO:0006417 regulation of translation(GO:0006417)
0.0 1.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.0 1.6 GO:0002218 activation of innate immune response(GO:0002218) pattern recognition receptor signaling pathway(GO:0002221) toll-like receptor signaling pathway(GO:0002224) innate immune response-activating signal transduction(GO:0002758)
0.0 0.3 GO:0031179 peptide modification(GO:0031179)
0.0 1.3 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 1.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.7 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.9 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.9 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 1.0 GO:2000027 regulation of organ morphogenesis(GO:2000027)
0.0 1.0 GO:0009615 response to virus(GO:0009615)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0019915 lipid storage(GO:0019915)
0.0 0.6 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0090148 membrane fission(GO:0090148)
0.0 0.6 GO:0035329 hippo signaling(GO:0035329)
0.0 0.6 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052) positive regulation of cellular protein catabolic process(GO:1903364)
0.0 4.2 GO:0006260 DNA replication(GO:0006260)
0.0 1.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.7 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 1.6 GO:0048565 digestive tract development(GO:0048565)
0.0 1.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.8 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 3.6 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 4.4 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 1.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.4 GO:0009913 epidermal cell differentiation(GO:0009913)
0.0 0.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.8 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 2.2 GO:0007059 chromosome segregation(GO:0007059)
0.0 5.7 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.0 3.8 GO:0006396 RNA processing(GO:0006396)
0.0 1.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.7 GO:0006412 translation(GO:0006412)
0.0 0.3 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.8 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.7 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0045446 endothelial cell differentiation(GO:0045446)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
1.3 8.8 GO:0070847 core mediator complex(GO:0070847)
1.2 3.5 GO:0030689 Noc complex(GO:0030689)
1.0 2.9 GO:0070545 PeBoW complex(GO:0070545)
0.9 2.7 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.9 2.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.7 2.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.6 1.9 GO:0070578 RISC-loading complex(GO:0070578)
0.6 3.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.6 2.2 GO:0033186 CAF-1 complex(GO:0033186)
0.5 5.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.5 1.6 GO:0032301 MutSalpha complex(GO:0032301)
0.5 2.8 GO:0016589 NURF complex(GO:0016589)
0.4 1.3 GO:0034457 Mpp10 complex(GO:0034457)
0.4 2.1 GO:0018444 translation release factor complex(GO:0018444)
0.4 4.6 GO:0005675 holo TFIIH complex(GO:0005675)
0.4 1.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 4.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 2.0 GO:0005879 axonemal microtubule(GO:0005879)
0.4 1.9 GO:0070724 BMP receptor complex(GO:0070724)
0.4 2.9 GO:0000796 condensin complex(GO:0000796)
0.3 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 2.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 1.6 GO:0031415 NatA complex(GO:0031415)
0.3 1.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 4.9 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.3 4.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 2.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 2.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 1.4 GO:0034657 GID complex(GO:0034657)
0.3 10.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 4.1 GO:0005579 membrane attack complex(GO:0005579)
0.3 3.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 2.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 4.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 2.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 1.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.2 0.4 GO:0097255 R2TP complex(GO:0097255)
0.2 0.6 GO:0043614 multi-eIF complex(GO:0043614)
0.2 4.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 0.7 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 1.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 1.4 GO:0031931 TORC1 complex(GO:0031931)
0.2 4.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 7.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.2 GO:0071818 BAT3 complex(GO:0071818)
0.2 0.5 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.2 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.2 0.5 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 2.0 GO:0002102 podosome(GO:0002102)
0.1 7.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 4.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.5 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 0.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.9 GO:0032797 SMN complex(GO:0032797)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.7 GO:0005869 dynactin complex(GO:0005869)
0.1 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 2.2 GO:0034399 nuclear periphery(GO:0034399)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.3 GO:0097541 axonemal basal plate(GO:0097541)
0.1 0.9 GO:0032021 NELF complex(GO:0032021)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.7 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 3.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 4.0 GO:0016592 mediator complex(GO:0016592)
0.1 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.6 GO:0005771 multivesicular body(GO:0005771)
0.1 1.8 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.3 GO:0042555 MCM complex(GO:0042555)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 1.1 GO:0070187 telosome(GO:0070187)
0.1 3.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.1 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 5.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.3 GO:0017177 glucosidase II complex(GO:0017177)
0.1 0.5 GO:0071546 pi-body(GO:0071546)
0.1 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.3 GO:0032039 integrator complex(GO:0032039)
0.1 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.4 GO:0005882 intermediate filament(GO:0005882)
0.0 2.1 GO:0000502 proteasome complex(GO:0000502)
0.0 7.5 GO:0005819 spindle(GO:0005819)
0.0 3.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.0 1.0 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.5 GO:0031514 motile cilium(GO:0031514)
0.0 9.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 5.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 3.2 GO:0005884 actin filament(GO:0005884)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 1.3 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 100.6 GO:0005634 nucleus(GO:0005634)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0005741 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.5 6.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.4 4.1 GO:0042806 fucose binding(GO:0042806)
1.2 6.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
1.2 4.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0 4.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.9 2.7 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.8 2.5 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.8 5.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.7 3.7 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.7 2.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.7 2.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.7 2.0 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.6 4.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.6 2.9 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.6 1.7 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.6 1.7 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.6 2.2 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.5 4.7 GO:0008494 translation activator activity(GO:0008494)
0.5 1.6 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.5 3.6 GO:0035173 histone kinase activity(GO:0035173)
0.5 1.5 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.5 1.5 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 1.9 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.5 1.4 GO:0000150 recombinase activity(GO:0000150)
0.5 1.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 3.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 1.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 1.2 GO:0000035 acyl binding(GO:0000035)
0.4 2.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 2.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 9.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.3 2.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 1.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 4.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 0.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 1.2 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.3 1.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 3.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 1.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 7.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 1.3 GO:0009374 biotin binding(GO:0009374)
0.2 0.7 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 2.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.1 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 2.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.3 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 2.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 2.3 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 2.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.5 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.2 1.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.5 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.2 2.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 1.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 5.1 GO:0051087 chaperone binding(GO:0051087)
0.2 3.1 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.4 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2 2.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 1.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 5.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.0 GO:2001069 glycogen binding(GO:2001069)
0.1 1.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.6 GO:0005542 folic acid binding(GO:0005542)
0.1 0.6 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.7 GO:0048156 tau protein binding(GO:0048156)
0.1 1.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 3.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.8 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 9.0 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 4.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 3.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 2.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 3.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 3.3 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 1.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 2.3 GO:0031072 heat shock protein binding(GO:0031072)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 8.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.4 GO:0019003 GDP binding(GO:0019003)
0.1 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 10.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 3.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 7.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 0.8 GO:0008144 drug binding(GO:0008144)
0.1 3.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 9.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.2 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0004096 catalase activity(GO:0004096)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 2.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 3.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 74.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.7 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 6.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 0.2 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 3.2 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 14.1 GO:0003677 DNA binding(GO:0003677)
0.0 13.2 GO:0003723 RNA binding(GO:0003723)
0.0 4.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 3.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.2 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 16.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 12.0 PID P53 REGULATION PATHWAY p53 pathway
0.2 9.1 PID PLK1 PATHWAY PLK1 signaling events
0.2 6.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 4.1 PID AURORA B PATHWAY Aurora B signaling
0.1 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 7.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 4.8 PID P73PATHWAY p73 transcription factor network
0.1 1.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 5.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 1.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.3 1.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 2.5 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.3 4.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 1.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 4.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 4.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 1.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 7.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 10.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 2.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 6.8 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 6.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 3.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 6.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 13.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 1.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 1.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 2.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 6.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 5.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.7 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.1 3.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 3.8 REACTOME MEIOSIS Genes involved in Meiosis
0.1 6.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 3.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)