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PRJEB1986: zebrafish developmental stages transcriptome

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Results for bsx

Z-value: 0.50

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Transcription factors associated with bsx

Gene Symbol Gene ID Gene Info
ENSDARG00000068976 brain-specific homeobox
ENSDARG00000110782 brain-specific homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bsxdr11_v1_chr10_-_29892486_298924860.418.0e-02Click!

Activity profile of bsx motif

Sorted Z-values of bsx motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_50888806 0.92 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr8_+_30452945 0.80 ENSDART00000062303
forkhead box D5
chr16_+_29509133 0.75 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr18_-_33979693 0.74 ENSDART00000021215
si:ch211-203b20.7
chr19_+_15440841 0.74 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr23_+_38251864 0.73 ENSDART00000183498
ENSDART00000129593
zinc finger protein 217
chr22_+_18315490 0.73 ENSDART00000160413
GATA zinc finger domain containing 2Ab
chr21_-_37973819 0.71 ENSDART00000133405
ripply transcriptional repressor 1
chr24_+_39638555 0.69 ENSDART00000078313
LUC7-like (S. cerevisiae)
chr15_-_20233105 0.68 ENSDART00000123910
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr5_+_50879545 0.68 ENSDART00000128402
nucleolar protein 6 (RNA-associated)
chr17_-_31659670 0.63 ENSDART00000030448
visual system homeobox 2
chr25_+_14507567 0.61 ENSDART00000015681
developing brain homeobox 1b
chr15_+_1796313 0.59 ENSDART00000126253
family with sequence similarity 124B
chr7_-_54679595 0.58 ENSDART00000165320
cyclin D1
chr19_+_15441022 0.58 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr2_+_20793982 0.56 ENSDART00000014785
proteoglycan 4a
chr1_+_23563691 0.56 ENSDART00000142879
non-SMC condensin I complex, subunit G
chr17_+_21295132 0.56 ENSDART00000103845
enolase family member 4
chr5_+_68807170 0.55 ENSDART00000017849
hairy and enhancer of split related-7
chr10_-_35257458 0.55 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr6_+_41191482 0.54 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr2_-_26596794 0.51 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr6_-_43283122 0.51 ENSDART00000186022
FERM domain containing 4Ba
chr2_-_20599315 0.49 ENSDART00000114199
si:ch211-267e7.3
chr12_-_42214 0.48 ENSDART00000045071
forkhead box K2
chr3_-_26183699 0.47 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr1_-_55248496 0.47 ENSDART00000098615
nanos homolog 3
chr11_+_18130300 0.46 ENSDART00000169146
zgc:175135
chr25_+_18965430 0.46 ENSDART00000169742
thymine DNA glycosylase, tandem duplicate 1
chr22_-_14272699 0.46 ENSDART00000190121
si:ch211-246m6.5
chr12_-_5728755 0.45 ENSDART00000105887
distal-less homeobox 4b
chr3_+_18807006 0.45 ENSDART00000180091
transportin 2 (importin 3, karyopherin beta 2b)
chr3_+_26244353 0.44 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr23_-_18913032 0.43 ENSDART00000136678
si:ch211-209j10.6
chr10_-_44560165 0.43 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr15_-_16177603 0.43 ENSDART00000156352
si:ch211-259g3.4
chr17_-_28101880 0.42 ENSDART00000149458
ENSDART00000149226
ENSDART00000085758
lysine (K)-specific demethylase 1a
chr13_-_42400647 0.42 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr3_-_16719244 0.42 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr8_+_21353878 0.42 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr3_-_26184018 0.42 ENSDART00000191604
si:ch211-11k18.4
chr3_+_23737795 0.42 ENSDART00000182247
homeobox B3a
chr16_+_28994709 0.42 ENSDART00000088023
gon-4-like (C. elegans)
chr2_+_4146606 0.42 ENSDART00000171170
mindbomb E3 ubiquitin protein ligase 1
chr18_+_17537344 0.41 ENSDART00000025782
nucleoporin 93
chr1_-_33645967 0.41 ENSDART00000192758
claudin g
chr25_-_29074064 0.40 ENSDART00000165603
AT rich interactive domain 3B (BRIGHT-like)
chr8_-_4892913 0.40 ENSDART00000126808
immunoglobulin superfamily, member 9b
chr12_-_26415499 0.39 ENSDART00000185779
synaptopodin 2-like b
chr10_+_22775253 0.39 ENSDART00000190141
transmembrane protein 88 a
chr2_+_4146299 0.39 ENSDART00000173418
mindbomb E3 ubiquitin protein ligase 1
chr21_-_37194365 0.39 ENSDART00000100286
fibroblast growth factor receptor 4
chr24_+_24170914 0.38 ENSDART00000127842
si:dkey-226l10.6
chr9_-_24031461 0.38 ENSDART00000021218
ribulose-5-phosphate-3-epimerase
chr5_+_66433287 0.37 ENSDART00000170757
kinetochore associated 1
chr2_-_55298075 0.37 ENSDART00000186404
ENSDART00000149062
RAB8A, member RAS oncogene family
chr9_-_27748868 0.37 ENSDART00000190306
TBCC domain containing 1
chr3_+_6469754 0.37 ENSDART00000185809
nucleoporin 85
chr19_-_7540821 0.37 ENSDART00000143958
limb and CNS expressed 1 like
chr12_-_35830625 0.37 ENSDART00000180028

chr9_-_20372977 0.37 ENSDART00000113418
immunoglobulin superfamily, member 3
chr19_-_19871211 0.36 ENSDART00000170980
even-skipped homeobox 1
chr12_+_16087077 0.36 ENSDART00000141898
zinc finger protein 281b
chr4_+_9177997 0.36 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr15_+_1534644 0.36 ENSDART00000130413
structural maintenance of chromosomes 4
chr15_-_14884332 0.35 ENSDART00000165237
si:ch211-24o8.4
chr12_-_26430507 0.35 ENSDART00000153214
synaptopodin 2-like b
chr5_+_1624359 0.35 ENSDART00000165431
protein phosphatase 1 catalytic subunit gamma
chr17_+_16046132 0.35 ENSDART00000155005
si:ch73-204p21.2
chr18_+_29898955 0.35 ENSDART00000064080
centromere protein N
chr23_-_40194732 0.35 ENSDART00000164931
transglutaminase 1 like 2
chr23_-_31913231 0.35 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr4_+_13428993 0.34 ENSDART00000067151
si:dkey-39a18.1
chr23_-_31913069 0.34 ENSDART00000135526
mitochondrial fission regulator 2
chr17_+_16046314 0.34 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr13_-_11984867 0.34 ENSDART00000157538
nucleophosmin/nucleoplasmin, 3
chr2_+_33326522 0.34 ENSDART00000056655
Kruppel-like factor 17
chr21_-_17296789 0.34 ENSDART00000192180
growth factor independent 1B transcription repressor
chr1_-_12064715 0.34 ENSDART00000143628
ENSDART00000103406
phospholipase A2, group XIIA
chr11_+_18157260 0.33 ENSDART00000144659
zgc:173545
chr8_+_48484455 0.33 ENSDART00000122737
si:ch211-263k4.2
chr13_-_21660203 0.33 ENSDART00000100925
mix-type homeobox gene 1
chr3_-_21288202 0.33 ENSDART00000191766
ENSDART00000187319
family with sequence similarity 171, member A2a
chr7_+_56098590 0.33 ENSDART00000098453
cadherin 15, type 1, M-cadherin (myotubule)
chr8_-_20243389 0.32 ENSDART00000184904
alkaline ceramidase 1
chr11_+_18175893 0.32 ENSDART00000177625
zgc:173545
chr6_-_40922971 0.31 ENSDART00000155363
SFI1 centrin binding protein
chr12_+_31638045 0.31 ENSDART00000184216
ENSDART00000183645
ENSDART00000153129
dynamin binding protein
chr21_-_43666420 0.31 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr11_-_6974022 0.31 ENSDART00000172851
si:ch211-43f4.1
chr5_-_41307550 0.31 ENSDART00000143446
natriuretic peptide receptor 3
chr4_+_14981854 0.31 ENSDART00000067046
cation/H+ exchanger protein 1
chr9_-_21460164 0.31 ENSDART00000133469
zinc finger, MYM-type 2
chr21_+_43404945 0.30 ENSDART00000142234
FERM domain containing 7
chr2_-_32666174 0.30 ENSDART00000133660
poly-U binding splicing factor a
chr23_+_11285662 0.30 ENSDART00000111028
cell adhesion molecule L1-like a
chr18_+_17537975 0.30 ENSDART00000179783
nucleoporin 93
chr12_-_33817114 0.30 ENSDART00000161265
twinkle mtDNA helicase
chr19_+_15521997 0.30 ENSDART00000003164
protein phosphatase 1, regulatory subunit 8a
chr19_+_19786117 0.30 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr2_+_56891858 0.30 ENSDART00000159912
zgc:85843
chr17_-_10043273 0.29 ENSDART00000156078
bromodomain adjacent to zinc finger domain, 1A
chr17_-_20118145 0.29 ENSDART00000149737
ENSDART00000165606
ryanodine receptor 2b (cardiac)
chr18_-_14777092 0.29 ENSDART00000144660
metastasis suppressor 1-like a
chr21_+_34088110 0.29 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr23_+_36095260 0.29 ENSDART00000127384
homeobox C9a
chr13_-_12005429 0.29 ENSDART00000180302
meningioma expressed antigen 5 (hyaluronidase)
chr13_+_17468161 0.29 ENSDART00000008906
zinc finger protein 503
chr5_+_27897504 0.28 ENSDART00000130936
ADAM metallopeptidase domain 28
chr2_-_38206034 0.28 ENSDART00000144518
ENSDART00000137395
apoptotic chromatin condensation inducer 1a
chr1_+_41588170 0.28 ENSDART00000139175
si:dkey-56e3.2
chr11_-_36341028 0.28 ENSDART00000146093
sortilin 1a
chr16_+_42471455 0.27 ENSDART00000166640
si:ch211-215k15.5
chr20_-_23426339 0.27 ENSDART00000004625
zygote arrest 1
chr3_+_13848226 0.27 ENSDART00000184342
interleukin enhancer binding factor 3b
chr10_-_41980797 0.27 ENSDART00000076575
ras homolog family member F
chr23_-_1017605 0.27 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr15_+_36309070 0.27 ENSDART00000157034
geminin coiled-coil domain containing
chr5_+_60590796 0.27 ENSDART00000159859
transmembrane protein 132E
chr24_-_10021341 0.26 ENSDART00000137250
zgc:173856
chr3_+_60721342 0.26 ENSDART00000157772
forkhead box J1a
chr23_-_25135046 0.26 ENSDART00000184844
ENSDART00000103989
isocitrate dehydrogenase 3 (NAD+) gamma
chr17_-_49412313 0.26 ENSDART00000152100
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr25_-_27722614 0.26 ENSDART00000190154
zgc:153935
chr24_+_37800102 0.26 ENSDART00000187591
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr21_-_13149453 0.26 ENSDART00000172578
si:dkey-228b2.6
chr19_+_31585917 0.26 ENSDART00000132182
geminin, DNA replication inhibitor
chr9_+_32073606 0.26 ENSDART00000184170
ENSDART00000180355
ENSDART00000110204
ENSDART00000123278
phosphoinositide kinase, FYVE finger containing
chr5_-_41142467 0.26 ENSDART00000129415
zinc finger RNA binding protein
chr25_+_35553542 0.26 ENSDART00000113723
Spi-1 proto-oncogene a
chr5_+_38913621 0.26 ENSDART00000137112
Fraser extracellular matrix complex subunit 1
chr1_+_33668236 0.25 ENSDART00000122316
ENSDART00000102184
ADP-ribosylation factor-like 13b
chr5_-_68333081 0.25 ENSDART00000168786
linker histone H1M
chr7_+_17816006 0.25 ENSDART00000080834
echinoderm microtubule associated protein like 3
chr21_-_36396334 0.25 ENSDART00000183627
mitochondrial ribosomal protein L22
chr21_+_28478663 0.25 ENSDART00000077887
ENSDART00000134150
solute carrier family 22 (organic anion transporter), member 6, like
chr10_-_23099809 0.25 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
notchless homolog 1 (Drosophila)
chr3_+_28860283 0.25 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr8_-_39822917 0.25 ENSDART00000067843
zgc:162025
chr5_-_31856681 0.24 ENSDART00000187817
protein kinase N3
chr17_-_25649079 0.24 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr22_-_27709692 0.24 ENSDART00000172458

chr11_+_24703108 0.24 ENSDART00000159173
G protein-coupled receptor 25
chr7_+_17816470 0.24 ENSDART00000173807
echinoderm microtubule associated protein like 3
chr24_-_4450238 0.24 ENSDART00000066835
frizzled class receptor 8a
chr10_-_28380919 0.24 ENSDART00000183409
ENSDART00000183105
ENSDART00000100207
ENSDART00000185392
ENSDART00000131220
B-cell translocation gene 3
chr1_+_34696503 0.24 ENSDART00000186106

chr5_-_65691512 0.24 ENSDART00000189255
notch 1b
chr21_-_30994577 0.24 ENSDART00000065503
post-GPI attachment to proteins 2
chr4_+_40265583 0.23 ENSDART00000151870
si:ch211-246n15.2
chr7_+_53498152 0.23 ENSDART00000184497
zinc finger protein 609b
chr17_-_31695217 0.23 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr19_+_16015881 0.23 ENSDART00000187135
CTP synthase 1a
chr5_+_30998764 0.23 ENSDART00000185783
ENSDART00000147874
ankyrin repeat and FYVE domain containing 1
chr20_-_48898560 0.23 ENSDART00000163071
5'-3' exoribonuclease 2
chr18_+_9171778 0.23 ENSDART00000101192
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr12_-_8504278 0.23 ENSDART00000135865
early growth response 2b
chr14_+_24845941 0.23 ENSDART00000187513
Rho guanine nucleotide exchange factor (GEF) 37
chr19_-_20403507 0.23 ENSDART00000052603
ENSDART00000137590
deleted in azoospermia-like
chr13_+_30903816 0.23 ENSDART00000191727
excision repair cross-complementation group 6
chr14_-_21959712 0.23 ENSDART00000021417
purinergic receptor P2X, ligand-gated ion channel, 3a
chr11_-_29563437 0.23 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr2_+_41526904 0.23 ENSDART00000127520
activin A receptor, type 1 like
chr6_+_50393047 0.22 ENSDART00000055502
ENSDART00000055511
ERGIC and golgi 3
chr19_+_12406583 0.22 ENSDART00000013865
ENSDART00000151535
SEH1-like (S. cerevisiae)
chr13_+_27232848 0.22 ENSDART00000138043
Ras and Rab interactor 2
chr8_-_23612462 0.22 ENSDART00000025024
solute carrier family 38, member 5b
chr13_+_36984794 0.22 ENSDART00000137328
FERM domain containing 6
chr10_+_26944418 0.22 ENSDART00000135493
FERM domain containing 8
chr17_+_24821627 0.21 ENSDART00000112389
WD repeat domain 43
chr18_-_25568994 0.21 ENSDART00000133029
si:ch211-13k12.2
chr4_-_74892355 0.21 ENSDART00000188725
PHD finger protein 21B
chr20_+_46513651 0.21 ENSDART00000152977
zinc finger CCCH-type containing 14
chr16_+_16266428 0.21 ENSDART00000188433
SET domain containing 2
chr21_+_33187992 0.21 ENSDART00000162745
ENSDART00000188388

chr15_-_23206562 0.21 ENSDART00000110360
coiled-coil domain containing 153
chr6_+_15762647 0.21 ENSDART00000127133
ENSDART00000128939
IQ motif containing with AAA domain 1
chr10_+_17371356 0.21 ENSDART00000122663
signal peptide peptidase 3
chr9_+_50316921 0.21 ENSDART00000098687
growth factor receptor bound protein 14
chr18_+_24921587 0.21 ENSDART00000191345
repulsive guidance molecule family member a
chr3_+_23738215 0.21 ENSDART00000143981
homeobox B3a
chr7_+_17908235 0.21 ENSDART00000077113
metastasis associated 1 family, member 2
chr7_-_17816175 0.21 ENSDART00000091272
ENSDART00000173757
ECSIT signalling integrator
chr10_+_518546 0.21 ENSDART00000128275
neuropeptide FF receptor 1 like 3
chr7_-_51368681 0.21 ENSDART00000146385
Rho GTPase activating protein 36
chr7_+_29863548 0.21 ENSDART00000136555
ENSDART00000134068
talin 2a
chr8_-_16788626 0.20 ENSDART00000191652

chr21_+_30746348 0.20 ENSDART00000050172
transient receptor potential cation channel, subfamily C, member 2b
chr15_+_436776 0.20 ENSDART00000008504
mediator complex subunit 17
chr16_+_14707960 0.20 ENSDART00000137912
collagen, type XIV, alpha 1a
chr16_-_41714988 0.20 ENSDART00000138798
centrosomal protein 85
chr11_-_18557929 0.20 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
death inducer-obliterator 1
chr10_+_23099890 0.20 ENSDART00000135890
si:dkey-175g6.5
chr5_-_12063381 0.20 ENSDART00000026749
nipsnap homolog 1 (C. elegans)
chr3_+_62205858 0.20 ENSDART00000126807
zgc:173575
chr4_-_2545310 0.20 ENSDART00000150619
ENSDART00000140760
E2F transcription factor 7
chr3_-_26244256 0.19 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr23_+_39695827 0.19 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr2_-_42071558 0.19 ENSDART00000142792
centrosome and spindle pole associated protein 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of bsx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.2 0.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.6 GO:0019323 pentose catabolic process(GO:0019323)
0.2 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 0.5 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.4 GO:2000726 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.4 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.4 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.4 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.2 GO:0060898 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.6 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.4 GO:0097065 anterior head development(GO:0097065)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.2 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.3 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.9 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.1 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.7 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.6 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.5 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 1.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910)
0.0 0.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 0.1 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:1900158 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.0 0.2 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.6 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.5 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.3 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)
0.1 1.2 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0097189 apoptotic body(GO:0097189)
0.0 0.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.6 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 1.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.5 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.2 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.7 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0098847 double-stranded telomeric DNA binding(GO:0003691) single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0031005 filamin binding(GO:0031005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling