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PRJEB1986: zebrafish developmental stages transcriptome

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Results for bcl6aa+bcl6ab+bcl6b

Z-value: 1.15

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Transcription factors associated with bcl6aa+bcl6ab+bcl6b

Gene Symbol Gene ID Gene Info
ENSDARG00000069295 BCL6A transcription repressor b
ENSDARG00000069335 BCL6B transcription repressor
ENSDARG00000070864 BCL6A transcription repressor a
ENSDARG00000111395 BCL6A transcription repressor a
ENSDARG00000112502 BCL6A transcription repressor a
ENSDARG00000116260 BCL6A transcription repressor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl6bdr11_v1_chr7_+_20019125_20019125-0.921.8e-08Click!
bcl6abdr11_v1_chr2_-_10098191_10098191-0.789.5e-05Click!
bcl6adr11_v1_chr6_-_28222592_28222592-0.381.0e-01Click!

Activity profile of bcl6aa+bcl6ab+bcl6b motif

Sorted Z-values of bcl6aa+bcl6ab+bcl6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_52061034 4.15 ENSDART00000170383

chr16_-_52879741 3.20 ENSDART00000166470
tubulin polymerization promoting protein
chr16_-_36834505 2.85 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr11_-_8167799 2.61 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
urate oxidase
chr17_-_6730247 2.33 ENSDART00000031091
visinin-like 1b
chr6_-_345503 2.29 ENSDART00000168901
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr20_+_10166297 2.27 ENSDART00000141877
potassium channel, subfamily K, member 10a
chr24_-_40009446 2.06 ENSDART00000087422
amine oxidase, copper containing 1
chr6_+_9881093 2.01 ENSDART00000151558
si:ch211-222n4.6
chr25_-_17395315 2.01 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr8_-_23783633 2.00 ENSDART00000132657
si:ch211-163l21.7
chr24_+_42948 1.92 ENSDART00000122785
thioredoxin related transmembrane protein 3b
chr23_-_35483163 1.89 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr22_+_7480465 1.76 ENSDART00000034545
zgc:92745
chr5_-_3209345 1.75 ENSDART00000171477

chr17_-_24564674 1.74 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr7_-_12869545 1.53 ENSDART00000163045
SH3-domain GRB2-like 3a
chr3_+_49021079 1.53 ENSDART00000162012
zgc:163083
chr18_+_49411417 1.51 ENSDART00000028944
zmp:0000001073
chr24_+_35947077 1.51 ENSDART00000173406
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr1_+_44053641 1.50 ENSDART00000124873
si:ch73-109d9.4
chr6_-_35446110 1.50 ENSDART00000058773
regulator of G protein signaling 16
chr21_+_11684830 1.40 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr9_-_21912227 1.40 ENSDART00000145576
LIM domain 7a
chr21_-_18982337 1.37 ENSDART00000147246
si:ch211-222n4.6
chr15_+_16521785 1.36 ENSDART00000062191
polypeptide N-acetylgalactosaminyltransferase 17
chr21_+_11685009 1.36 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr16_+_45746549 1.36 ENSDART00000190403
progestin and adipoQ receptor family member VI
chr9_-_6372535 1.34 ENSDART00000149189
esophageal cancer related gene 4a
chr15_-_40246396 1.34 ENSDART00000063777
potassium inwardly-rectifying channel, subfamily J, member 13
chr23_+_45229198 1.33 ENSDART00000172445
tetratricopeptide repeat domain 39B
chr11_-_762721 1.32 ENSDART00000166465
synapsin IIb
chr5_+_63668735 1.27 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr4_-_18436899 1.25 ENSDART00000141671
suppressor of cytokine signaling 2
chr11_-_22303678 1.24 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr3_+_12861158 1.23 ENSDART00000171237
potassium inwardly-rectifying channel, subfamily J, member 2b
chr7_+_38509333 1.21 ENSDART00000153482
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr25_-_20258508 1.20 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr6_+_9175886 1.19 ENSDART00000165333
si:ch211-207l14.1
chr18_+_50907675 1.18 ENSDART00000159950
si:ch1073-450f2.1
chr23_+_29966466 1.16 ENSDART00000143583
dishevelled segment polarity protein 1a
chr3_+_19299309 1.14 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr8_+_1189798 1.13 ENSDART00000193474
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr1_-_54765262 1.12 ENSDART00000150362
si:ch211-197k17.3
chr21_-_2238277 1.12 ENSDART00000165754
si:dkey-50i6.6
chr1_-_55008882 1.11 ENSDART00000083572
zgc:136864
chr22_+_28337429 1.09 ENSDART00000166177
interphotoreceptor matrix proteoglycan 2b
chr2_+_38556195 1.08 ENSDART00000138769
cadherin 24, type 2b
chr9_-_9282519 1.08 ENSDART00000146821
si:ch211-214p13.3
chr21_-_41588129 1.07 ENSDART00000164125
creb3 regulatory factor
chr25_-_29415369 1.05 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr11_-_40742424 1.05 ENSDART00000173399
ENSDART00000021369
taste receptor, type 1, member 3
chr18_-_6460102 1.05 ENSDART00000137037
IQ motif and Sec7 domain 3b
chr4_-_8152746 1.05 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr7_+_73295890 1.05 ENSDART00000174331
ENSDART00000174250

chr21_+_5209476 1.04 ENSDART00000146400
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr12_+_5530247 1.03 ENSDART00000114637
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr9_-_8670158 1.03 ENSDART00000077296
collagen, type IV, alpha 1
chr2_-_10703621 1.02 ENSDART00000005944
ribosomal protein L5a
chr2_-_38125657 0.97 ENSDART00000143433
cerebellin 12
chr2_-_37465517 0.96 ENSDART00000139983
si:dkey-57k2.6
chr16_+_16849220 0.92 ENSDART00000047409
ENSDART00000142155
myosin, heavy chain 14, non-muscle
chr5_+_28849155 0.92 ENSDART00000079090
zgc:174259
chr4_-_67969695 0.91 ENSDART00000190016
si:ch211-223k15.1
chr6_+_41503854 0.91 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cytokine inducible SH2-containing protein
chr2_+_38554260 0.91 ENSDART00000171527
cadherin 24, type 2b
chr19_-_20114149 0.90 ENSDART00000052620
neuropeptide Y
chr15_-_2903475 0.89 ENSDART00000043226
guanylate cyclase activator 1C
chr20_+_41664350 0.87 ENSDART00000186247
family with sequence similarity 184, member A
chr19_-_47587719 0.87 ENSDART00000111108

chr9_+_42157578 0.87 ENSDART00000142888
leucine rich repeat containing 3
chr13_-_37631092 0.85 ENSDART00000108855
si:dkey-188i13.7
chr9_+_8851819 0.85 ENSDART00000160004
collagen, type IV, alpha 2
chr7_-_6425549 0.85 ENSDART00000173323
zgc:165555
chr14_-_2206476 0.84 ENSDART00000081870
protocadherin 2 alpha b 6
chr25_-_35137391 0.83 ENSDART00000182510
zgc:165555
chr10_-_30785501 0.83 ENSDART00000020054
opioid binding protein/cell adhesion molecule-like
chr21_+_15870752 0.83 ENSDART00000122015
family with sequence similarity 169, member Ab
chr5_+_9360394 0.82 ENSDART00000124642

chr11_-_43226255 0.80 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr13_-_11644806 0.79 ENSDART00000169953
dynactin 1b
chr25_-_8160030 0.79 ENSDART00000067159
tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a
chr20_+_6493648 0.78 ENSDART00000099846
meprin A, beta
chr3_+_39656188 0.78 ENSDART00000186292
ENSDART00000156038
epsin 2
chr16_+_22761846 0.77 ENSDART00000193028

chr20_-_16548912 0.77 ENSDART00000137601
checkpoint suppressor 1
chr23_-_1571682 0.76 ENSDART00000013635
F-box protein 30b
chr7_+_14005111 0.76 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr19_-_6631900 0.75 ENSDART00000144571
poliovirus receptor-related 2 like
chr19_-_6134802 0.75 ENSDART00000140051
capicua transcriptional repressor a
chr20_-_40367493 0.75 ENSDART00000075096
sphingomyelin phosphodiesterase, acid-like 3A
chr14_-_2196267 0.74 ENSDART00000161674
ENSDART00000125674
protocadherin 2 alpha b 8
protocadherin 2 alpha b 9
chr11_+_29770966 0.73 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr22_+_1462177 0.73 ENSDART00000164685
si:dkeyp-53d3.5
chr22_+_37902976 0.73 ENSDART00000169327
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr20_+_29586529 0.72 ENSDART00000178617
ADAM metallopeptidase domain 17b
chr10_+_585719 0.72 ENSDART00000180167
SMAD family member 4a
chr7_+_13039426 0.72 ENSDART00000171777
synaptotagmin VIIb
chr16_-_27749172 0.71 ENSDART00000145198
STEAP family member 4
chr8_+_11687254 0.70 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr13_+_33688474 0.70 ENSDART00000161465

chr11_+_43375326 0.70 ENSDART00000130131
sulfotransferase family, cytosolic, 6b, member 1
chr13_-_2112008 0.69 ENSDART00000110814
family with sequence similarity 83, member B
chr25_-_8030113 0.69 ENSDART00000104674
calcium/calmodulin-dependent protein kinase 1Db
chr1_-_9195629 0.68 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr13_-_37608441 0.68 ENSDART00000140230
zgc:123068
chr7_+_61764040 0.67 ENSDART00000056745
acyl-CoA oxidase 3, pristanoyl
chr2_+_3428357 0.64 ENSDART00000125967

chr17_-_50331351 0.64 ENSDART00000149294
otoferlin b
chr21_-_22676323 0.64 ENSDART00000167392
grass carp reovirus (GCRV)-induced gene 2h
chr6_+_40591149 0.63 ENSDART00000189060
ENSDART00000188298
fibroblast growth factor receptor substrate 3
chr21_+_26720803 0.63 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr18_-_7400075 0.62 ENSDART00000101250
si:dkey-30c15.13
chr7_-_71837213 0.61 ENSDART00000168645
ENSDART00000160512
calcium channel, voltage-dependent, beta 2a
chr4_+_359970 0.61 ENSDART00000139832
transmembrane protein 181
chr13_-_47554194 0.61 ENSDART00000181508
acyl-CoA oxidase-like
chr10_-_18468385 0.61 ENSDART00000183302
si:dkey-28o19.1
chr22_+_26804197 0.61 ENSDART00000135688
si:dkey-44g23.2
chr1_-_46663997 0.61 ENSDART00000134450
emopamil binding protein-like
chr1_+_10221568 0.61 ENSDART00000152424
neuropeptide Y receptor Y2, like
chr18_-_43880020 0.60 ENSDART00000185638
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr16_-_45398408 0.60 ENSDART00000004052
ral guanine nucleotide dissociation stimulator-like 2
chr5_+_25952340 0.60 ENSDART00000147188
transient receptor potential cation channel, subfamily M, member 3
chr18_-_44888375 0.60 ENSDART00000160506
si:ch211-71n6.4
chr8_-_46700278 0.58 ENSDART00000143780
G protein-coupled receptor 153
chr12_-_28983584 0.57 ENSDART00000112374
zgc:171713
chr5_-_23118290 0.57 ENSDART00000132857
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr18_+_3634652 0.57 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr1_+_41454210 0.57 ENSDART00000148251
si:ch211-89o9.4
chr14_-_27121854 0.57 ENSDART00000173119
protocadherin 11
chr13_-_50234122 0.56 ENSDART00000164338
eukaryotic translation initiation factor 2-alpha kinase 2
chr9_+_51265283 0.56 ENSDART00000137426
glucagon b
chr18_+_45228691 0.56 ENSDART00000127953
LARGE xylosyl- and glucuronyltransferase 2
chr21_+_31811202 0.55 ENSDART00000189846
si:ch211-12m10.1
chr23_-_30960506 0.55 ENSDART00000142661
oxysterol binding protein-like 2a
chr22_-_17844117 0.55 ENSDART00000159363

chr25_-_21822426 0.55 ENSDART00000151993
zgc:158222
chr16_-_31933740 0.55 ENSDART00000125411
si:ch1073-90m23.1
chr20_-_25551676 0.55 ENSDART00000063081
cytochrome P450, family 2, subfamily AD, polypeptide 3
chr20_+_4793790 0.54 ENSDART00000153486
galectin 8a
chr23_+_2185397 0.53 ENSDART00000109373
C1q and TNF related 7
chr21_+_1378250 0.53 ENSDART00000186912
transcription factor 4
chr20_-_47188966 0.53 ENSDART00000152965
si:dkeyp-104f11.9
chr3_-_44059902 0.52 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr7_-_16204885 0.52 ENSDART00000171008
bloodthirsty-related gene family, member 5
chr25_+_11281970 0.52 ENSDART00000180094
si:dkey-187e18.1
chr21_+_26073104 0.51 ENSDART00000193273
ribosomal protein L23a
chr7_-_11596450 0.51 ENSDART00000173863
StAR-related lipid transfer (START) domain containing 5
chr9_+_1313418 0.51 ENSDART00000191361
caspase 8, apoptosis-related cysteine peptidase, like 2
chr10_+_21722892 0.50 ENSDART00000162855
protocadherin 1 gamma 13
chr7_-_24373662 0.50 ENSDART00000173865
si:dkey-11k2.7
chr21_+_12010505 0.50 ENSDART00000123522
aquaporin 7
chr19_+_32856907 0.50 ENSDART00000148232
ribosomal protein L30
chr9_-_23922011 0.49 ENSDART00000145734
collagen, type VI, alpha 3
chr5_-_55600689 0.48 ENSDART00000013229
guanine nucleotide binding protein (G protein), q polypeptide
chr18_+_10689772 0.48 ENSDART00000126441
leptin a
chr1_-_56596701 0.48 ENSDART00000133693

chr15_-_23793641 0.48 ENSDART00000122891
transmembrane protein 97
chr25_+_37397031 0.48 ENSDART00000193643
ENSDART00000169132
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr7_+_5529967 0.47 ENSDART00000142709
si:dkeyp-67a8.4
chr17_-_23631400 0.47 ENSDART00000079563
Fas cell surface death receptor
chr14_-_6987649 0.47 ENSDART00000060990
eukaryotic translation initiation factor 4E binding protein 3, like
chr12_-_26558038 0.46 ENSDART00000039510
transporter associated with antigen processing, subunit type t, teleost specific
chr5_-_5035683 0.46 ENSDART00000170025
LIM homeobox transcription factor 1, beta a
chr3_-_30888415 0.45 ENSDART00000124458
lysine methyltransferase 5C
chr24_-_1356668 0.45 ENSDART00000188935
neuropilin 1a
chr21_+_39361040 0.44 ENSDART00000085453
clustered mitochondria (cluA/CLU1) homolog b
chr14_-_11507211 0.44 ENSDART00000186873
ENSDART00000109181
ENSDART00000186166
ENSDART00000186986
zgc:174917
chr16_-_41004731 0.44 ENSDART00000102591
si:dkey-201i6.2
chr11_+_36409457 0.44 ENSDART00000077641
cytochrome b561 family, member D1
chr24_+_37370064 0.44 ENSDART00000185870
si:ch211-183d21.3
chr16_+_10329701 0.43 ENSDART00000172845
mediator of DNA damage checkpoint 1
chr13_-_37122217 0.43 ENSDART00000133242
spectrin repeat containing, nuclear envelope 2b
chr21_-_2248239 0.43 ENSDART00000169448
si:ch73-299h12.1
chr19_-_35229336 0.43 ENSDART00000054274
microtubule-actin crosslinking factor 1a
chr22_-_11493236 0.43 ENSDART00000002691
tetraspanin 7b
chr1_-_47114310 0.42 ENSDART00000144899
ENSDART00000053157
SET domain containing 4
chr8_+_28667021 0.42 ENSDART00000184292
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr24_+_22039964 0.41 ENSDART00000081220
ankyrin repeat domain 33ba
chr1_+_11736420 0.41 ENSDART00000140329
carbohydrate (chondroitin 4) sulfotransferase 12b
chr15_+_5321612 0.41 ENSDART00000174345
odorant receptor, family A, subfamily 113, member 1
chr7_-_19168375 0.41 ENSDART00000112447
interleukin 13 receptor, alpha 1
chr19_-_3821678 0.40 ENSDART00000169639
si:dkey-206d17.12
chr7_+_66739166 0.40 ENSDART00000154634
murine retrovirus integration site 1 homolog
chr9_+_38502524 0.39 ENSDART00000087229
leishmanolysin-like (metallopeptidase M8 family)
chr18_+_6479963 0.39 ENSDART00000092752
ENSDART00000136333
WAS protein family homolog 1
chr23_+_42292748 0.39 ENSDART00000166113
ENSDART00000158684
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr10_+_22134606 0.39 ENSDART00000155228
si:dkey-4c2.11
chr14_+_23929059 0.39 ENSDART00000159582
SH3 domain containing ring finger 2
chr16_-_17162843 0.39 ENSDART00000089386
intermediate filament family orphan 1b
chr15_-_2010926 0.38 ENSDART00000155688
dedicator of cytokinesis 10
chr24_-_37472727 0.38 ENSDART00000134152
clusterin associated protein 1
chr1_-_40341306 0.37 ENSDART00000190649
mastermind-like transcriptional coactivator 3
chr11_+_45287541 0.37 ENSDART00000165321
ENSDART00000173116
pyrroline-5-carboxylate reductase 1b
chr9_+_29585943 0.37 ENSDART00000185989
ENSDART00000115290
mcf.2 cell line derived transforming sequence-like b
chr8_+_47099033 0.36 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr1_-_40208237 0.36 ENSDART00000191987

chr9_+_12948511 0.36 ENSDART00000135797
si:dkey-230p4.1
chr21_-_43398457 0.36 ENSDART00000166530
cyclin I family, member 2
chr18_+_18863167 0.36 ENSDART00000091094
plasmolipin

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl6aa+bcl6ab+bcl6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.5 1.9 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.4 1.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 2.1 GO:0046677 response to antibiotic(GO:0046677)
0.4 2.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.3 1.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.3 1.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 2.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 3.5 GO:0016486 peptide hormone processing(GO:0016486)
0.2 0.9 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.2 0.6 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 1.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 0.7 GO:0015677 copper ion import(GO:0015677)
0.1 0.4 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 0.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.5 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.1 0.5 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.3 GO:0003403 optic vesicle formation(GO:0003403)
0.1 0.3 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.6 GO:0050951 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.1 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0002858 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.4 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.6 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.3 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.0 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.6 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 2.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.5 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.2 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.8 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.2 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.5 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.2 GO:0050688 regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 1.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.0 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 2.1 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.5 GO:0001508 action potential(GO:0001508)
0.0 0.3 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 1.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 2.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 0.8 GO:0008091 spectrin(GO:0008091)
0.1 1.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.6 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.8 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.4 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 4.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 2.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 2.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 2.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 1.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 1.1 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.3 1.9 GO:0016972 thiol oxidase activity(GO:0016972)
0.3 1.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 1.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.9 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 0.7 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 0.5 GO:0046978 TAP1 binding(GO:0046978)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 2.4 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0032052 bile acid binding(GO:0032052)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.2 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.0 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.8 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.2 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing