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PRJEB1986: zebrafish developmental stages transcriptome

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Results for barx2

Z-value: 1.55

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Transcription factors associated with barx2

Gene Symbol Gene ID Gene Info
ENSDARG00000041098 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barx2dr11_v1_chr18_+_47313715_473137150.474.4e-02Click!

Activity profile of barx2 motif

Sorted Z-values of barx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_46313082 3.30 ENSDART00000153830
si:ch1073-190k2.1
chr8_+_23521974 2.90 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr11_+_24002503 2.48 ENSDART00000164702
chitinase, acidic.2
chr23_-_21446985 2.35 ENSDART00000044080
hairy-related 12
chr1_+_52662203 2.20 ENSDART00000141530
oxysterol binding protein
chr18_-_48983690 2.16 ENSDART00000182359

chr18_+_3579829 2.15 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
leucine-rich repeats and calponin homology (CH) domain containing 3
chr16_+_28994709 2.11 ENSDART00000088023
gon-4-like (C. elegans)
chr23_+_40460333 2.06 ENSDART00000184658
SOGA family member 3b
chr25_+_37126921 1.99 ENSDART00000124331
si:ch1073-174d20.1
chr4_+_2482046 1.90 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr6_-_12588044 1.82 ENSDART00000047896
solute carrier family 15 (oligopeptide transporter), member 1b
chr24_-_29586082 1.82 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr20_-_47188966 1.73 ENSDART00000152965
si:dkeyp-104f11.9
chr3_-_12026741 1.63 ENSDART00000132238
cilia and flagella associated protein 70
chr21_-_2814709 1.63 ENSDART00000097664
semaphorin 4D
chr5_+_71802014 1.59 ENSDART00000124939
ENSDART00000097164
LIM homeobox 3
chr1_-_19502322 1.53 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr8_+_6576940 1.50 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr8_+_26141680 1.35 ENSDART00000078334
cadherin, EGF LAG seven-pass G-type receptor 3
chr20_+_41664350 1.34 ENSDART00000186247
family with sequence similarity 184, member A
chr23_-_900795 1.34 ENSDART00000190517
ENSDART00000182849
ENSDART00000111456
ENSDART00000185430
RNA binding motif protein 10
chr3_-_40054615 1.31 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr12_-_7854216 1.30 ENSDART00000149594
ankyrin 3b
chr3_-_59297532 1.28 ENSDART00000187991

chr1_-_2457546 1.27 ENSDART00000103795
gamma-glutamylamine cyclotransferase, tandem duplicate 1
chr9_+_2574122 1.27 ENSDART00000166326
ENSDART00000191822
si:ch73-167c12.2
chr2_-_17694504 1.25 ENSDART00000133709
protein tyrosine phosphatase, receptor type, f, b
chr21_-_36571804 1.24 ENSDART00000138129
WW and C2 domain containing 1
chr3_+_35542067 1.20 ENSDART00000146529
ENSDART00000084549
RNA pseudouridylate synthase domain containing 1
chr19_-_42045372 1.19 ENSDART00000144275
trio Rho guanine nucleotide exchange factor a
chr20_-_53078607 1.17 ENSDART00000163494
ENSDART00000191730

chr23_+_7710721 1.17 ENSDART00000186852
ENSDART00000161193
kinesin family member 3B
chr7_-_25895189 1.17 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr11_-_6974022 1.16 ENSDART00000172851
si:ch211-43f4.1
chr12_+_4971515 1.16 ENSDART00000161076
Rho GTPase activating protein 27
chr3_+_62339264 1.14 ENSDART00000174569

chr9_+_7998794 1.14 ENSDART00000138167
myosin XVI
chr8_-_50888806 1.14 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr11_+_45436703 1.12 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr20_-_9095105 1.10 ENSDART00000140792
OMA1 zinc metallopeptidase
chr4_-_2219705 1.09 ENSDART00000131046
si:ch73-278m9.1
chr5_-_66702479 1.09 ENSDART00000129197
meningioma 1b
chr22_+_2769236 1.07 ENSDART00000141836
si:dkey-20i20.10
chr9_+_24065855 1.07 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr15_-_40157513 1.07 ENSDART00000184014
si:ch211-281l24.3
chr1_+_54124209 1.07 ENSDART00000187730

chr15_-_40157331 1.07 ENSDART00000187958
si:ch211-281l24.3
chr10_-_33297864 1.06 ENSDART00000163360
PR/SET domain 15
chr19_+_1688727 1.05 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr1_-_47071979 1.05 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr21_-_13972745 1.04 ENSDART00000143874
AT-hook transcription factor
chr19_-_26869103 1.03 ENSDART00000089699
proline-rich transmembrane protein 1
chr23_+_2789422 1.03 ENSDART00000156954
phospholipase C, gamma 1
chr12_-_48006835 1.03 ENSDART00000108989
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr22_-_21897203 1.01 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr16_+_54209504 0.99 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr15_-_40267485 0.98 ENSDART00000152253
potassium inwardly-rectifying channel, subfamily J, member 13
chr25_+_35891342 0.98 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr5_-_51198430 0.97 ENSDART00000132503
ENSDART00000097473
ENSDART00000165870
small nuclear RNA activating complex, polypeptide 4
chr10_+_45089820 0.96 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr22_-_37797695 0.95 ENSDART00000085931
ENSDART00000185443
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr11_+_29975830 0.95 ENSDART00000148929
si:ch73-226l13.2
chr17_-_16422654 0.92 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr25_+_16116740 0.92 ENSDART00000139778
fatty acyl CoA reductase 1
chr8_+_25767610 0.92 ENSDART00000062406
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr7_-_31922432 0.92 ENSDART00000188398
lin-7 homolog C (C. elegans)
chr7_+_24573721 0.91 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr17_-_200316 0.91 ENSDART00000190561

chr23_-_26521970 0.91 ENSDART00000143712
si:dkey-205h13.1
chr8_+_7097929 0.90 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
ankyrin repeat and BTB (POZ) domain containing 1
chr5_+_19933356 0.90 ENSDART00000088819
ankyrin repeat domain 13A
chr13_+_646700 0.89 ENSDART00000006892
tumor protein p53 binding protein, 2a
chr9_+_21277846 0.89 ENSDART00000139620
ENSDART00000110996
ENSDART00000111899
large tumor suppressor kinase 2
chr1_-_56080112 0.88 ENSDART00000075469
ENSDART00000161473
complement component c3a, duplicate 6
chr18_+_50461981 0.87 ENSDART00000158761

chr13_+_24750078 0.87 ENSDART00000021053
collagen, type XVII, alpha 1b
chr24_+_7336807 0.86 ENSDART00000137010
lysine (K)-specific methyltransferase 2Ca
chr15_-_40157165 0.86 ENSDART00000192991
si:ch211-281l24.3
chr12_-_35885349 0.83 ENSDART00000085662
centrosomal protein 131
chr7_+_26534131 0.83 ENSDART00000173980
si:dkey-62k3.5
chr8_-_19246342 0.83 ENSDART00000147172
abhydrolase domain containing 17Ab
chr7_+_1530024 0.82 ENSDART00000163082
TOX high mobility group box family member 4 b
chr10_-_21054059 0.82 ENSDART00000139733
protocadherin 1a
chr19_+_19775757 0.81 ENSDART00000164677
homeobox A3a
chr1_+_11977426 0.80 ENSDART00000103399
tetraspanin 5b
chr17_+_49281597 0.80 ENSDART00000155599
zgc:113176
chr19_-_205104 0.80 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr16_+_11623956 0.80 ENSDART00000137788
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr20_-_35578435 0.78 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr2_-_58142854 0.78 ENSDART00000169909

chr1_-_5455498 0.78 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr25_-_19420949 0.77 ENSDART00000181338
microtubule-associated protein 1Ab
chr17_+_50524573 0.76 ENSDART00000187974

chr23_+_45785563 0.76 ENSDART00000186027

chr15_-_14552101 0.76 ENSDART00000171169
numb homolog (Drosophila)-like
chr15_-_47115787 0.76 ENSDART00000192601

chr9_+_48761455 0.76 ENSDART00000139631
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr1_+_39482588 0.75 ENSDART00000181790
teneurin transmembrane protein 3
chr7_-_71829649 0.75 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr22_+_18816662 0.75 ENSDART00000132476
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr1_+_51312752 0.74 ENSDART00000063938
microtubule associated serine/threonine kinase 1a
chr11_+_29770966 0.74 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr22_-_37796998 0.74 ENSDART00000124742
ENSDART00000191232
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr20_-_39333657 0.73 ENSDART00000153720
ENSDART00000142164
chemokine (C-C motif) ligand 38, duplicate 1
chr19_+_40069524 0.73 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr5_+_63668735 0.73 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr7_+_53156810 0.73 ENSDART00000189816
cadherin 29
chr2_-_3678029 0.72 ENSDART00000146861
matrix metallopeptidase 16b (membrane-inserted)
chr10_-_2524917 0.72 ENSDART00000188642

chr17_-_20717845 0.72 ENSDART00000150037
ankyrin 3b
chr23_-_18024543 0.71 ENSDART00000139695
peptidase M20 domain containing 1, tandem duplicate 1
chr22_-_17844117 0.71 ENSDART00000159363

chr23_-_33709964 0.70 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr10_-_37072776 0.70 ENSDART00000110835
myosin XVIIIAa
chr23_-_1660708 0.69 ENSDART00000175138

chr21_+_21195487 0.69 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr23_-_1017605 0.69 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr24_+_23840821 0.69 ENSDART00000128595
ENSDART00000127188
polymerase (DNA directed), alpha 1
chr21_-_44081540 0.69 ENSDART00000130833

chr6_+_612594 0.69 ENSDART00000150903
kynureninase
chr11_-_40742424 0.68 ENSDART00000173399
ENSDART00000021369
taste receptor, type 1, member 3
chr19_-_6239248 0.68 ENSDART00000014127
POU class 2 homeobox 2a
chr12_+_48480632 0.68 ENSDART00000158157
Rho GTPase activating protein 44
chr12_-_314899 0.68 ENSDART00000066579
6-pyruvoyltetrahydropterin synthase
chr24_+_36204028 0.68 ENSDART00000063832
ENSDART00000155260
retinoblastoma binding protein 8
chr24_+_7336411 0.68 ENSDART00000191170
lysine (K)-specific methyltransferase 2Ca
chr17_-_29224908 0.68 ENSDART00000156288
si:dkey-28g23.6
chr8_+_52637507 0.67 ENSDART00000163830
si:dkey-90l8.3
chr21_-_2232640 0.67 ENSDART00000157754
zgc:113343
chr3_-_1989000 0.67 ENSDART00000193936

chr8_-_7567815 0.67 ENSDART00000132536
host cell factor C1b
chr1_+_6862917 0.67 ENSDART00000182953
erb-b2 receptor tyrosine kinase 4a
chr14_-_30387894 0.66 ENSDART00000176136
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr19_+_31873308 0.65 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr2_-_59205393 0.65 ENSDART00000056417
ENSDART00000182452
ENSDART00000141876
finTRIM family, member 30
chr17_-_4245902 0.64 ENSDART00000151851
growth differentiation factor 3
chr9_-_32604414 0.64 ENSDART00000088876
ENSDART00000166502
SATB homeobox 2
chr9_+_48415043 0.64 ENSDART00000159930
low density lipoprotein receptor-related protein 2a
chr21_+_6394929 0.63 ENSDART00000138600
si:ch211-225g23.1
chr19_-_47323267 0.62 ENSDART00000190077

chr13_-_18122333 0.62 ENSDART00000128748
WASH complex subunit 2C
chr5_+_66433287 0.62 ENSDART00000170757
kinetochore associated 1
chr11_+_23760470 0.62 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr19_+_24891747 0.62 ENSDART00000132209
ENSDART00000193610
EYA transcriptional coactivator and phosphatase 3
chr7_-_54679595 0.62 ENSDART00000165320
cyclin D1
chr15_-_18162647 0.62 ENSDART00000012064
PIH1 domain containing 2
chr17_+_41992054 0.61 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr24_-_6078222 0.61 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_+_42726712 0.61 ENSDART00000028955
tudor domain containing 3
chr7_+_19552381 0.61 ENSDART00000169060
si:ch211-212k18.5
chr6_-_39649504 0.61 ENSDART00000179960
ENSDART00000190951
La ribonucleoprotein domain family, member 4Ab
chr17_+_6625717 0.60 ENSDART00000190753
ENSDART00000181298

chr25_-_25058508 0.60 ENSDART00000087570
ENSDART00000178891

chr11_+_31323746 0.59 ENSDART00000180220
ENSDART00000189937
signal-induced proliferation-associated 1 like 2
chr10_+_42733210 0.59 ENSDART00000189832

chr10_-_43404027 0.59 ENSDART00000086227
EGF-like repeats and discoidin I-like domains 3b
chr5_+_21891305 0.59 ENSDART00000136788
si:ch73-92i20.1
chr6_-_29305132 0.59 ENSDART00000132456
basic, immunoglobulin-like variable motif containing
chr13_+_35339182 0.59 ENSDART00000019323
jagged 1b
chr9_-_47472998 0.59 ENSDART00000134480
tensin 1b
chr22_-_9896180 0.58 ENSDART00000138343
zinc finger protein 990
chr5_-_11809710 0.58 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr17_-_2386569 0.58 ENSDART00000121614
phospholipase C beta 2
chr5_-_6377865 0.58 ENSDART00000031775
zgc:73226
chr3_+_38540411 0.58 ENSDART00000154943
si:dkey-7f16.3
chr6_-_1432200 0.57 ENSDART00000182901

chr14_-_48765262 0.57 ENSDART00000166463
CCR4-NOT transcription complex, subunit 6b
chr6_-_6487876 0.57 ENSDART00000137642
centrosomal protein 170Ab
chr18_-_30020879 0.57 ENSDART00000162086
si:ch211-220f16.2
chr15_-_34845414 0.57 ENSDART00000009892
gamma-aminobutyric acid (GABA) B receptor, 1a
chr6_-_21189295 0.56 ENSDART00000137136
obscurin-like 1a
chr1_-_46981134 0.56 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr23_+_4022620 0.56 ENSDART00000055099
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr3_+_62205858 0.55 ENSDART00000126807
zgc:173575
chr23_-_25779995 0.55 ENSDART00000110670
si:dkey-21c19.3
chr6_+_59832786 0.55 ENSDART00000154985
ENSDART00000102148
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr3_-_10749691 0.55 ENSDART00000183088

chr8_+_24299321 0.55 ENSDART00000112046
ENSDART00000183558
ENSDART00000183796
ENSDART00000181395
ENSDART00000184555
ENSDART00000172531
ENSDART00000191663
ENSDART00000184103
ENSDART00000183676
si:ch211-269m15.3
chr3_+_57268363 0.54 ENSDART00000180725
transmembrane protein 235
chr15_+_32297441 0.54 ENSDART00000153657
tripartite motif containing 3a
chr1_-_9195629 0.54 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr7_+_66884291 0.54 ENSDART00000187499
SET binding factor 2
chr22_-_22337382 0.53 ENSDART00000144684
si:ch211-129c21.1
chr2_+_48073972 0.53 ENSDART00000186442
Kruppel-like factor 6b
chr10_+_15967643 0.53 ENSDART00000136709
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr7_-_11596450 0.53 ENSDART00000173863
StAR-related lipid transfer (START) domain containing 5
chr12_-_48188928 0.53 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr24_+_9475809 0.53 ENSDART00000132688
si:ch211-285f17.1
chr9_-_9348058 0.53 ENSDART00000132257
zgc:113337
chr12_-_9294819 0.53 ENSDART00000003805
parathyroid hormone 1 receptor b
chr5_-_14373662 0.53 ENSDART00000183694
tet methylcytosine dioxygenase 3
chr17_+_16564921 0.53 ENSDART00000151904
forkhead box N3
chr3_-_40955780 0.52 ENSDART00000130130
cytochrome P450, family 3, subfamily c, polypeptide 3
chr2_-_17393216 0.52 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr10_-_2524297 0.52 ENSDART00000192475

chr22_-_18179214 0.52 ENSDART00000129576
si:ch211-125m10.6
chr23_-_26652273 0.51 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr1_-_669717 0.51 ENSDART00000160564
cysteine/tyrosine-rich 1
chr15_-_755023 0.51 ENSDART00000155594
zinc finger protein 1011

Network of associatons between targets according to the STRING database.

First level regulatory network of barx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0000012 single strand break repair(GO:0000012)
0.4 1.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.3 1.0 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.3 1.9 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 1.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 0.7 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.2 2.5 GO:0006032 chitin catabolic process(GO:0006032)
0.2 0.7 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.2 1.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.8 GO:0006857 oligopeptide transport(GO:0006857)
0.2 0.8 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 0.8 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 0.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.2 GO:0032475 otolith formation(GO:0032475)
0.2 0.7 GO:0006272 leading strand elongation(GO:0006272)
0.2 1.2 GO:0043584 nose development(GO:0043584)
0.1 0.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 1.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.5 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.0 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.8 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 0.7 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.7 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.3 GO:0035973 aggrephagy(GO:0035973)
0.1 0.5 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.5 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 1.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 1.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.3 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.9 GO:0046620 regulation of organ growth(GO:0046620)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.8 GO:0070293 renal absorption(GO:0070293)
0.1 0.4 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.9 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.7 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.8 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 2.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 0.3 GO:0042138 mitotic G2 DNA damage checkpoint(GO:0007095) meiotic DNA double-strand break formation(GO:0042138)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.4 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.4 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0001881 receptor recycling(GO:0001881)
0.0 0.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.9 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.3 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 1.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0030814 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.7 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.7 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 2.3 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.1 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.2 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0008216 spermidine metabolic process(GO:0008216) polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.4 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.6 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.3 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.6 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.0 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.6 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 0.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 2.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.4 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.6 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 2.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.4 GO:0016459 myosin complex(GO:0016459)
0.0 1.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 0.9 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 1.8 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.2 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.5 GO:0004568 chitinase activity(GO:0004568)
0.2 0.7 GO:0070336 flap-structured DNA binding(GO:0070336)
0.2 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 0.8 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.2 0.6 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2 1.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.9 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.4 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.1 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 1.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.5 GO:0032052 bile acid binding(GO:0032052)
0.1 2.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.2 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 3.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 5.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 1.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.8 GO:0003774 motor activity(GO:0003774)
0.0 3.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0002020 protease binding(GO:0002020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases