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PRJEB1986: zebrafish developmental stages transcriptome

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Results for barhl1a+barhl1b

Z-value: 2.71

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Transcription factors associated with barhl1a+barhl1b

Gene Symbol Gene ID Gene Info
ENSDARG00000019013 BarH-like homeobox 1b
ENSDARG00000035508 BarH-like homeobox 1a
ENSDARG00000110061 BarH-like homeobox 1a
ENSDARG00000112355 BarH-like homeobox 1a
ENSDARG00000113145 BarH-like homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barhl1bdr11_v1_chr21_-_17482465_17482465-0.409.0e-02Click!
barhl1adr11_v1_chr5_-_29750377_29750377-0.068.1e-01Click!

Activity profile of barhl1a+barhl1b motif

Sorted Z-values of barhl1a+barhl1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_8362419 15.66 ENSDART00000142752
ENSDART00000135810
acid phosphatase 5a, tartrate resistant
chr22_+_14093306 12.39 ENSDART00000080329
ENSDART00000115383
hatching enzyme 1, tandem duplicate 1
chr3_-_19368435 8.61 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr4_+_15006217 7.00 ENSDART00000090837
zinc finger, C3HC-type containing 1
chr19_+_15444210 5.56 ENSDART00000142509
lin-28 homolog A (C. elegans)
chr16_-_32303835 5.55 ENSDART00000191408
MMS22-like, DNA repair protein
chr7_+_34236238 5.45 ENSDART00000052474
timeless interacting protein
chr4_+_73606482 5.27 ENSDART00000150765
si:ch211-165i18.2
chr3_+_31093455 5.22 ENSDART00000153074
si:dkey-66i24.9
chr19_-_47571456 5.22 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr7_-_54678289 5.03 ENSDART00000170774
cyclin D1
chr3_-_61387273 4.99 ENSDART00000156479
zinc finger protein 1143
chr10_-_35257458 4.99 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr8_+_30452945 4.91 ENSDART00000062303
forkhead box D5
chr24_-_41797681 4.84 ENSDART00000169643
Rho GTPase activating protein 28
chr23_+_31913292 4.72 ENSDART00000136910
armadillo repeat containing 1, like
chr20_-_53992952 4.72 ENSDART00000170138
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr20_+_33294428 4.65 ENSDART00000024104
MYCN proto-oncogene, bHLH transcription factor
chr2_-_10098191 4.62 ENSDART00000138081
B-cell CLL/lymphoma 6a, genome duplicate b
chr16_+_40576679 4.48 ENSDART00000169412
ENSDART00000193464
cyclin E2
chr5_-_69437422 4.43 ENSDART00000073676
iron-sulfur cluster assembly 1
chr4_-_12477224 4.39 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr13_-_35908275 4.30 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr20_-_32148901 4.28 ENSDART00000153405
ENSDART00000048537
ENSDART00000152984
centrosomal protein 57, like 1
chr6_+_3473657 4.28 ENSDART00000011785
RAD54 like
chr13_+_15701849 4.25 ENSDART00000003517
tRNA methyltransferase 61A
chr23_-_25779995 4.21 ENSDART00000110670
si:dkey-21c19.3
chr5_+_24087035 4.10 ENSDART00000183644
tumor protein p53
chr14_-_17072736 4.08 ENSDART00000106333
paired-like homeobox 2bb
chr20_-_38827623 4.08 ENSDART00000153310
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr23_-_10722664 4.07 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
forkhead box P1a
chr2_+_27386617 4.05 ENSDART00000134976
si:ch73-382f3.1
chr12_+_14149686 4.04 ENSDART00000123741
kelch repeat and BTB (POZ) domain containing 2
chr16_+_29376751 4.04 ENSDART00000168856
ENSDART00000162502
ENSDART00000050535
ribosomal RNA adenine dimethylase domain containing 1
chr1_+_49352900 4.00 ENSDART00000008468
muscle segment homeobox 1b
chr23_+_35713557 3.99 ENSDART00000123518
tubulin, alpha 1c
chr22_-_21314821 3.99 ENSDART00000105546
ENSDART00000135388
CDC28 protein kinase regulatory subunit 2
chr2_-_38080075 3.96 ENSDART00000056544
TOX high mobility group box family member 4 a
chr22_-_10541372 3.92 ENSDART00000179708
si:dkey-42i9.4
chr5_-_32505109 3.85 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr5_+_32831561 3.83 ENSDART00000169358
ENSDART00000192078
si:ch211-208h16.4
chr3_+_22442445 3.83 ENSDART00000190921
WNK lysine deficient protein kinase 4b
chr3_-_50066499 3.81 ENSDART00000056618
ENSDART00000154561
mitochondrial ribosomal protein L12
chr16_-_31824525 3.79 ENSDART00000058737
cell division cycle 42, like
chr5_-_32505276 3.76 ENSDART00000034705
ENSDART00000187597
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr1_-_31515746 3.75 ENSDART00000190886
centromere protein K
chr18_+_29898955 3.74 ENSDART00000064080
centromere protein N
chr19_+_3213914 3.72 ENSDART00000193144
zgc:86598
chr6_+_11760749 3.71 ENSDART00000112212
zinc finger, SWIM-type containing 2
chr19_+_41509956 3.68 ENSDART00000171318
ENSDART00000172311
si:ch211-57n23.1
chr7_+_25000060 3.63 ENSDART00000039265
ENSDART00000141814
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr2_-_29994726 3.59 ENSDART00000163350
canopy1
chr16_+_48626780 3.58 ENSDART00000157364
pre-B-cell leukemia homeobox 2
chr2_-_17115256 3.47 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr11_-_40519886 3.45 ENSDART00000172819
migration and invasion inhibitory protein
chr1_-_55166511 3.44 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr2_-_16449504 3.41 ENSDART00000144801
ATR serine/threonine kinase
chr13_-_31296358 3.41 ENSDART00000030946
PR domain containing 8
chr23_+_24955394 3.31 ENSDART00000142124
nucleolar protein 9
chr16_-_34195002 3.21 ENSDART00000054026
regulator of chromosome condensation 1
chr18_+_7639401 3.19 ENSDART00000092416
RAB, member of RAS oncogene family-like 2
chr12_+_23664335 3.17 ENSDART00000111334
mitochondrial poly(A) polymerase
chr4_-_9350585 3.15 ENSDART00000148155
si:ch211-125a15.1
chr5_+_60847823 3.14 ENSDART00000074426
ligase III, DNA, ATP-dependent
chr2_+_32826235 3.12 ENSDART00000143127
si:dkey-154p10.3
chr8_+_20863025 3.12 ENSDART00000015891
ENSDART00000187089
ENSDART00000146989
fizzy/cell division cycle 20 related 1a
chr2_-_26469065 3.12 ENSDART00000099247
ENSDART00000099248
Rab geranylgeranyltransferase, beta subunit
chr9_+_38314466 3.09 ENSDART00000048753
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr14_+_21820034 3.08 ENSDART00000122739
C-terminal binding protein 1
chr19_-_11315224 3.02 ENSDART00000104933
endonuclease/exonuclease/phosphatase family domain containing 1
chr20_-_54924593 2.97 ENSDART00000151522
si:dkey-15f23.1
chr9_-_34300707 2.95 ENSDART00000049805
immunoglobulin-like domain containing receptor 2
chr7_+_25126629 2.92 ENSDART00000077217
zgc:101765
chr13_+_6189203 2.92 ENSDART00000109665
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr13_+_6188759 2.87 ENSDART00000161062
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr1_-_55116453 2.86 ENSDART00000142348
SERTA domain containing 2a
chr19_+_29808471 2.86 ENSDART00000186428
histone deacetylase 1
chr16_+_26732086 2.85 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr3_-_15352303 2.84 ENSDART00000104338
ENSDART00000145919
ENSDART00000132135
phosphatidylinositol transfer protein, beta, like
chr22_-_38258053 2.83 ENSDART00000132516
ELAV like neuron-specific RNA binding protein 2
chr11_+_30295582 2.80 ENSDART00000122424
UDP glucuronosyltransferase 1 family, polypeptide B7
chr23_+_31912882 2.77 ENSDART00000140505
armadillo repeat containing 1, like
chr17_-_45387134 2.76 ENSDART00000010975
transmembrane protein 206
chr19_-_33274978 2.75 ENSDART00000020301
ENSDART00000114714
family with sequence similarity 92, member A1
chr18_+_5308392 2.75 ENSDART00000179072
deoxyuridine triphosphatase
chr7_-_20464133 2.74 ENSDART00000078192
canopy4
chr12_-_20409794 2.66 ENSDART00000077936
leucine carboxyl methyltransferase 1
chr13_-_35907768 2.64 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr13_+_16279890 2.64 ENSDART00000101775
ENSDART00000057948
annexin A11a
chr6_-_6976096 2.63 ENSDART00000151822
ENSDART00000039443
ENSDART00000177960
tubulin, alpha 8 like 4
chr3_+_54761569 2.63 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
chr9_+_52411530 2.62 ENSDART00000163684
NME/NM23 family member 8
chr22_+_17120473 2.61 ENSDART00000170076
ENSDART00000090217
Fras1 related extracellular matrix 1b
chr5_+_36900157 2.60 ENSDART00000183533
ENSDART00000051184
heterogeneous nuclear ribonucleoprotein L
chr14_+_21686207 2.59 ENSDART00000034438
RAN, member RAS oncogene family
chr25_+_1732838 2.59 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr23_+_32011768 2.58 ENSDART00000053509
pleiomorphic adenoma gene X
chr23_+_19813677 2.58 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr3_+_17910569 2.57 ENSDART00000080946
tetratricopeptide repeat domain 25
chr13_+_9896368 2.57 ENSDART00000137388
si:ch211-117n7.8
chr16_+_20055878 2.57 ENSDART00000146436
ankyrin repeat domain 28b
chr13_+_9896845 2.56 ENSDART00000169076
si:ch211-117n7.8
chr16_-_43344859 2.55 ENSDART00000058680
proteasome subunit alpha 2
chr3_+_12554801 2.53 ENSDART00000167177
cyclin F
chr11_+_6136220 2.53 ENSDART00000082223
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr18_+_6536598 2.52 ENSDART00000149350
FK506 binding protein 4
chr10_+_10728870 2.52 ENSDART00000109282
SWI5 homologous recombination repair protein
chr14_-_38929885 2.51 ENSDART00000148737
Bruton agammaglobulinemia tyrosine kinase
chr19_-_20777351 2.50 ENSDART00000019206
N-glycanase 1
chr25_-_26753196 2.49 ENSDART00000155698
ubiquitin specific peptidase 3
chr23_-_31913231 2.48 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr2_+_22495274 2.48 ENSDART00000167915
leucine rich repeat containing 8 VRAC subunit Da
chr16_+_15114645 2.48 ENSDART00000158483
MDM2 binding protein
chr20_-_20901540 2.47 ENSDART00000010564
ENSDART00000131273
X-ray repair complementing defective repair in Chinese hamster cells 3
chr21_-_25565392 2.47 ENSDART00000144917
ENSDART00000180102
si:dkey-17e16.10
chr15_-_14193926 2.46 ENSDART00000162707
polynucleotide kinase 3'-phosphatase
chr17_-_33716688 2.45 ENSDART00000043651
dynein, axonemal, light chain 1
chr12_+_16087077 2.44 ENSDART00000141898
zinc finger protein 281b
chr1_-_31516091 2.44 ENSDART00000139828
ENSDART00000146567
centromere protein K
chr7_-_24644893 2.43 ENSDART00000048921
GP1 homolog, RAB6A GEF complex partner 1
chr2_+_16449627 2.43 ENSDART00000005381
zgc:110269
chr11_-_33618612 2.42 ENSDART00000033980
LIM and senescent cell antigen-like domains 1
chr16_-_35415004 2.40 ENSDART00000170401
ENSDART00000157832
ENSDART00000170048
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_-_33477588 2.39 ENSDART00000144150
calcium/calmodulin-dependent serine protein kinase a
chr10_-_13116337 2.39 ENSDART00000164568
muscle, skeletal, receptor tyrosine kinase
chr18_-_7448047 2.38 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
chr12_+_28910762 2.36 ENSDART00000076342
ENSDART00000160939
ENSDART00000076572
ring finger protein 40
chr7_-_24112484 2.36 ENSDART00000111923
ajuba LIM protein
chr25_+_17590095 2.35 ENSDART00000009767
vac14 homolog (S. cerevisiae)
chr7_+_56517402 2.35 ENSDART00000073597
dihydroorotate dehydrogenase
chr2_-_37103622 2.35 ENSDART00000137849
zgc:101744
chr3_+_7040363 2.35 ENSDART00000157805

chr7_+_38260434 2.35 ENSDART00000052351
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr3_-_32859335 2.35 ENSDART00000158916
si:dkey-16l2.20
chr19_-_874888 2.33 ENSDART00000007206
eomesodermin homolog a
chr9_+_500052 2.31 ENSDART00000166707

chr15_-_41689684 2.31 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr3_+_22035863 2.30 ENSDART00000177169
cell division cycle 27
chr25_-_12923482 2.28 ENSDART00000161754

chr21_+_10756154 2.27 ENSDART00000074833
retinal homeobox gene 3
chr23_-_20345473 2.27 ENSDART00000140935
si:rp71-17i16.6
chr17_+_24446353 2.27 ENSDART00000140467
UDP-glucose pyrophosphorylase 2b
chr23_-_24955135 2.24 ENSDART00000136347
ENSDART00000144903
zinc finger and BTB domain containing 48
chr13_-_35808904 2.24 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr5_+_51833132 2.21 ENSDART00000167491
PAP associated domain containing 4
chr18_-_34549721 2.21 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr11_-_25461336 2.21 ENSDART00000014945
host cell factor C1a
chr11_+_37612214 2.21 ENSDART00000172899
ENSDART00000077496
heterochromatin protein 1, binding protein 3
chr22_+_10010292 2.21 ENSDART00000180096

chr10_-_11397590 2.21 ENSDART00000064212
SREK1-interacting protein 1
chr3_+_22036113 2.19 ENSDART00000132190
cell division cycle 27
chr1_+_29267841 2.17 ENSDART00000085648
ligase IV, DNA, ATP-dependent
chr3_+_22443313 2.17 ENSDART00000156450
WNK lysine deficient protein kinase 4b
chr12_+_34119439 2.17 ENSDART00000032821
cytohesin 1b
chr16_+_20056030 2.16 ENSDART00000027020
ankyrin repeat domain 28b
chr5_-_33280699 2.16 ENSDART00000183838
kynurenine aminotransferase 1
chr5_+_57714902 2.15 ENSDART00000182860
ubiquitin-fold modifier conjugating enzyme 1
chr5_-_56943064 2.14 ENSDART00000146991
si:ch211-127d4.3
chr5_+_53580846 2.14 ENSDART00000184967
ENSDART00000161751
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_-_25761544 2.13 ENSDART00000078152
suppressor of variegation 3-9 homolog 1b
chr25_-_3347418 2.12 ENSDART00000082385
golgi transport 1Bb
chr3_+_45365098 2.11 ENSDART00000052746
ENSDART00000156555
ubiquitin-conjugating enzyme E2Ia
chr16_+_11779534 2.10 ENSDART00000133497
si:dkey-250k15.4
chr5_+_32141790 2.08 ENSDART00000041504
tescalcin b
chr4_-_18840487 2.07 ENSDART00000066978
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr9_+_8968702 2.07 ENSDART00000008490
ubiquitin conjugating enzyme E2 A, like
chr18_+_48423973 2.07 ENSDART00000184233
ENSDART00000147074
Fli-1 proto-oncogene, ETS transcription factor a
chr10_+_25947946 2.06 ENSDART00000064393
ubiquitin-fold modifier 1
chr19_+_46237665 2.05 ENSDART00000159391
vacuolar protein sorting 28 (yeast)
chr20_+_26556372 2.05 ENSDART00000187179
ENSDART00000157291
interferon regulatory factor 4b
chr9_-_21488976 2.05 ENSDART00000080404
M-phase phosphoprotein 8
chr10_+_42733210 2.04 ENSDART00000189832

chr6_+_296130 2.04 ENSDART00000073985
RNA binding fox-1 homolog 2
chr14_+_7892383 2.03 ENSDART00000063837
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr23_+_20431388 2.03 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
solute carrier family 35 (GDP-fucose transporter), member C2
chr2_-_29923403 2.03 ENSDART00000144672
PAX interacting (with transcription-activation domain) protein 1
chr17_-_45386823 2.02 ENSDART00000156002
transmembrane protein 206
chr17_+_24597001 2.01 ENSDART00000191834
rearranged L-myc fusion
chr20_+_26556174 2.01 ENSDART00000138492
interferon regulatory factor 4b
chr19_+_24891747 2.01 ENSDART00000132209
ENSDART00000193610
EYA transcriptional coactivator and phosphatase 3
chr2_+_6243144 2.00 ENSDART00000058258
guanine nucleotide binding protein (G protein), gamma 5
chr12_+_20583552 2.00 ENSDART00000170035
arylsulfatase G
chr13_+_22717939 1.99 ENSDART00000188288
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr3_-_32590164 1.99 ENSDART00000151151
tetraspanin 4b
chr21_+_37090795 1.99 ENSDART00000085786
zinc finger protein 346
chr24_+_16905188 1.98 ENSDART00000066760
chaperonin containing TCP1, subunit 5 (epsilon)
chr2_+_307665 1.96 ENSDART00000082083
zgc:113452
chr15_+_34699585 1.96 ENSDART00000017569
tumor necrosis factor b (TNF superfamily, member 2)
chr19_+_2685779 1.96 ENSDART00000160533
ENSDART00000097531
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr6_-_52348562 1.95 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr20_-_10120442 1.95 ENSDART00000144970
Meis homeobox 2b
chr21_-_36396334 1.94 ENSDART00000183627
mitochondrial ribosomal protein L22
chr5_-_32890807 1.93 ENSDART00000007512
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr18_+_49248389 1.93 ENSDART00000059285
ENSDART00000142004
ENSDART00000132751
Yip1 interacting factor homolog B (S. cerevisiae)
chr7_+_26466826 1.92 ENSDART00000058908
mannose-P-dolichol utilization defect 1b
chr10_-_8032885 1.92 ENSDART00000188619
ATPase H+ transporting V0 subunit a2a
chr10_+_10386435 1.92 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sarcosine dehydrogenase
chr23_+_27051919 1.91 ENSDART00000054237
prostaglandin E synthase 3a (cytosolic)
chr17_+_24446533 1.90 ENSDART00000131417
UDP-glucose pyrophosphorylase 2b
chr2_-_32386791 1.87 ENSDART00000056634
upstream binding transcription factor, like

Network of associatons between targets according to the STRING database.

First level regulatory network of barhl1a+barhl1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
1.4 15.7 GO:0045453 bone resorption(GO:0045453)
1.4 4.1 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
1.4 4.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.3 5.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.2 6.0 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
1.2 4.7 GO:0045428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
1.2 5.8 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.1 5.5 GO:0043111 replication fork arrest(GO:0043111)
1.1 5.3 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
1.0 4.1 GO:0061549 sympathetic ganglion development(GO:0061549)
1.0 5.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.9 3.8 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.8 2.5 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.8 4.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.8 2.4 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.8 2.4 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.8 2.3 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.8 2.3 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.7 6.8 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.7 2.0 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.6 2.6 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.6 1.9 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.6 1.9 GO:1901052 sarcosine metabolic process(GO:1901052)
0.6 4.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.6 9.9 GO:0051382 kinetochore assembly(GO:0051382)
0.6 5.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.6 3.0 GO:1901207 regulation of heart looping(GO:1901207)
0.6 1.8 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 3.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.5 4.1 GO:0032196 transposition(GO:0032196)
0.5 3.0 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.5 1.9 GO:0006272 leading strand elongation(GO:0006272)
0.5 3.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.5 5.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 2.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.5 5.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.5 3.2 GO:1901673 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.4 3.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.4 5.1 GO:0016926 protein desumoylation(GO:0016926)
0.4 2.9 GO:0033687 osteoblast proliferation(GO:0033687)
0.4 3.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.4 1.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.4 1.8 GO:0002159 desmosome assembly(GO:0002159)
0.4 1.1 GO:0060306 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.4 5.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.3 5.5 GO:0031297 replication fork processing(GO:0031297)
0.3 2.4 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.3 1.0 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.3 2.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.3 4.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 2.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 2.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.3 1.2 GO:0021795 substrate-dependent cell migration(GO:0006929) pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.3 1.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 2.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 2.5 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.3 1.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 1.8 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.3 3.6 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.3 0.8 GO:0071514 genetic imprinting(GO:0071514)
0.2 2.5 GO:0006517 protein deglycosylation(GO:0006517)
0.2 4.8 GO:0051098 regulation of binding(GO:0051098)
0.2 2.7 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.2 2.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 2.0 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 3.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 1.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 3.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 1.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 3.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 2.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 2.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 1.8 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) embryonic skeletal joint development(GO:0072498)
0.2 2.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.8 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.0 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.2 4.0 GO:0000154 rRNA modification(GO:0000154)
0.2 0.6 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2 0.9 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 3.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.8 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 2.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 4.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 1.9 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) chaperone-mediated protein complex assembly(GO:0051131)
0.1 3.2 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 4.4 GO:0016574 histone ubiquitination(GO:0016574)
0.1 1.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 4.0 GO:0043049 otic placode formation(GO:0043049)
0.1 2.6 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.7 GO:0080009 mRNA methylation(GO:0080009)
0.1 5.0 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.5 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 2.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 4.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.6 GO:0071428 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 1.8 GO:0048665 neuron fate specification(GO:0048665)
0.1 3.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.5 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 1.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 3.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 2.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 3.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 1.8 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 2.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.7 GO:0007286 spermatid development(GO:0007286)
0.1 1.1 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.7 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 3.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 2.9 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.1 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 3.6 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.1 2.0 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 2.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 1.0 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.5 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 2.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.2 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 1.5 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.4 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 8.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 2.5 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 2.8 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 4.4 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 3.7 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 0.8 GO:0042476 odontogenesis(GO:0042476)
0.0 2.6 GO:0007492 endoderm development(GO:0007492)
0.0 2.1 GO:0034968 histone lysine methylation(GO:0034968)
0.0 2.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.3 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.1 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.0 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 1.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.9 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 1.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.9 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 2.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 1.7 GO:0003341 cilium movement(GO:0003341)
0.0 3.9 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.4 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 2.4 GO:0006260 DNA replication(GO:0006260)
0.0 2.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.1 GO:0051607 defense response to virus(GO:0051607)
0.0 1.0 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 2.2 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 3.9 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 2.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0002250 adaptive immune response(GO:0002250)
0.0 3.4 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 6.7 GO:0000278 mitotic cell cycle(GO:0000278)
0.0 1.2 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
1.1 4.5 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
1.1 4.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
1.1 5.5 GO:0031298 replication fork protection complex(GO:0031298)
1.0 4.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.8 4.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.8 2.5 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.8 3.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.7 2.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.5 5.5 GO:0035101 FACT complex(GO:0035101)
0.5 2.5 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.5 1.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 2.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 2.1 GO:0033503 HULC complex(GO:0033503)
0.4 1.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.4 3.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 2.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 2.4 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 3.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.3 7.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 2.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 11.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 1.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 2.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.1 GO:0070695 FHF complex(GO:0070695)
0.2 2.4 GO:0014704 intercalated disc(GO:0014704)
0.2 2.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 2.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 1.4 GO:0071546 pi-body(GO:0071546)
0.2 3.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 1.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.2 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 6.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 2.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 4.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.5 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.7 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 1.8 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.1 GO:0000124 SAGA complex(GO:0000124)
0.1 2.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 3.5 GO:0005657 replication fork(GO:0005657)
0.1 2.2 GO:0005694 chromosome(GO:0005694)
0.1 1.6 GO:0015030 Cajal body(GO:0015030)
0.1 1.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 3.8 GO:0030496 midbody(GO:0030496)
0.1 8.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 1.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.6 GO:0030286 dynein complex(GO:0030286)
0.1 1.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 4.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 3.1 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 6.2 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 2.7 GO:0000786 nucleosome(GO:0000786)
0.0 154.6 GO:0005634 nucleus(GO:0005634)
0.0 1.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 2.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
2.0 15.7 GO:0003993 acid phosphatase activity(GO:0003993)
1.8 5.3 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.4 4.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.3 8.8 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
1.2 5.0 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
1.2 7.1 GO:0015616 DNA translocase activity(GO:0015616)
1.2 5.8 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
1.1 8.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.9 3.8 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.8 4.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.8 4.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.8 3.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.8 3.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.7 5.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.7 4.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.7 2.2 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.7 2.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.7 3.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.6 2.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6 2.4 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.5 2.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.5 1.9 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5 1.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 2.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 6.0 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.4 5.8 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.4 1.4 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.4 1.8 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 2.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 1.0 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 2.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 5.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 4.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 2.7 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.3 2.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.3 4.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 2.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.3 0.8 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 3.6 GO:0051117 ATPase binding(GO:0051117)
0.2 2.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 12.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 4.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 2.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 2.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.7 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 3.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.2 1.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.9 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 8.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.5 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 6.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.4 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 1.1 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 5.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 8.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 13.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 6.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 2.1 GO:0000049 tRNA binding(GO:0000049)
0.1 0.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.6 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 2.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 4.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 3.1 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 2.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 6.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 15.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.6 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 2.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 37.7 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.1 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 5.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 4.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.3 5.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 13.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 9.4 PID ATR PATHWAY ATR signaling pathway
0.1 3.1 PID ATM PATHWAY ATM pathway
0.1 2.5 ST GA12 PATHWAY G alpha 12 Pathway
0.1 3.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.0 ST GA13 PATHWAY G alpha 13 Pathway
0.1 3.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 9.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 4.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 8.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 5.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 2.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.3 6.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3 7.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 5.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 2.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 1.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 2.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 2.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 2.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 9.6 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 1.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 5.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway