Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for atf2+atf7a+atf7b_creb5a+creb5b

Z-value: 0.83

Motif logo

Transcription factors associated with atf2+atf7a+atf7b_creb5a+creb5b

Gene Symbol Gene ID Gene Info
ENSDARG00000011298 activating transcription factor 7a
ENSDARG00000023903 activating transcription factor 2
ENSDARG00000055481 activating transcription factor 7b
ENSDARG00000114492 activating transcription factor 7b
ENSDARG00000115171 activating transcription factor 7b
ENSDARG00000070536 cAMP responsive element binding protein 5b
ENSDARG00000099002 cAMP responsive element binding protein 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf7adr11_v1_chr23_-_27479558_274795580.502.9e-02Click!
atf7bdr11_v1_chr6_-_39631164_396311810.381.1e-01Click!
atf2dr11_v1_chr9_+_2343096_23431720.331.7e-01Click!
creb5adr11_v1_chr19_-_19505167_195051670.155.3e-01Click!
creb5bdr11_v1_chr16_-_20707742_20707742-0.048.7e-01Click!

Activity profile of atf2+atf7a+atf7b_creb5a+creb5b motif

Sorted Z-values of atf2+atf7a+atf7b_creb5a+creb5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_33121535 1.13 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr22_+_1911269 1.06 ENSDART00000164158
ENSDART00000168205
zinc finger protein 1156
chr15_+_28685625 0.90 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr15_+_28685892 0.88 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr7_-_12065668 0.87 ENSDART00000101537
mex-3 RNA binding family member B
chr5_+_69808763 0.81 ENSDART00000143482
fibronectin type III and SPRY domain containing 1-like
chr5_+_56268436 0.79 ENSDART00000021159
LIM homeobox 1b
chr24_+_4373355 0.69 ENSDART00000179062
ENSDART00000093256
ENSDART00000138943
cyclin Y
chr4_+_77060861 0.68 ENSDART00000174271
ENSDART00000174393
ENSDART00000150450
si:dkey-240n22.8
chr20_-_24122881 0.67 ENSDART00000131857
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
chr9_-_306515 0.67 ENSDART00000166059
si:ch211-166e11.5
chr19_-_1961024 0.65 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_44037843 0.63 ENSDART00000160276
si:ch73-109d9.3
chr22_+_2315996 0.61 ENSDART00000132489
zinc finger protein 1175
chr7_+_7552008 0.60 ENSDART00000173018
ENSDART00000049311
chloride channel 3
chr3_+_53116172 0.57 ENSDART00000115117
bromodomain containing 4
chr16_-_32649929 0.57 ENSDART00000136161
failed axon connections homolog b
chr20_-_32446406 0.57 ENSDART00000026635
nuclear receptor subfamily 2, group E, member 1
chr23_+_34990693 0.56 ENSDART00000013449
si:ch211-236h17.3
chr3_-_5964557 0.55 ENSDART00000184738

chr4_+_77141970 0.54 ENSDART00000174209
si:dkey-172k15.11
chr2_+_58877162 0.53 ENSDART00000122174

chr22_+_38935060 0.53 ENSDART00000183732
ENSDART00000130055
sirtuin 7
chr3_-_16413606 0.52 ENSDART00000127309
ENSDART00000017172
ENSDART00000136465
elongation factor Tu GTP binding domain containing 2
chr23_-_25686894 0.52 ENSDART00000181420
ENSDART00000088208
low density lipoprotein receptor-related protein 1Ab
chr4_+_77151419 0.52 ENSDART00000174312

chr24_+_39638555 0.51 ENSDART00000078313
LUC7-like (S. cerevisiae)
chr3_-_49566364 0.51 ENSDART00000161507
zgc:153426
chr4_-_64482414 0.51 ENSDART00000159000
zinc finger protein 1105
chr17_+_23554932 0.50 ENSDART00000135814
pantothenate kinase 1a
chr15_-_34658057 0.50 ENSDART00000110964
BCL2 associated athanogene 6
chr22_+_30330574 0.50 ENSDART00000104751
max interactor 1, dimerization protein
chr20_-_37933237 0.49 ENSDART00000142567
ENSDART00000036371
ENSDART00000061445
angel homolog 2 (Drosophila)
chr22_+_2183110 0.46 ENSDART00000159279
ENSDART00000121703
zinc finger protein 1152
chr24_-_19718077 0.45 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr9_+_219124 0.45 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr20_+_29743904 0.45 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr1_-_23595779 0.44 ENSDART00000134860
ENSDART00000138852
ligand dependent nuclear receptor corepressor-like
chr8_+_29742237 0.43 ENSDART00000133955
ENSDART00000020621
mitogen-activated protein kinase 4
chr21_-_23308286 0.42 ENSDART00000184419
zinc finger and BTB domain containing 16a
chr16_+_34523515 0.41 ENSDART00000041007
stathmin 1b
chr16_+_25137483 0.41 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr25_+_19201231 0.41 ENSDART00000067323
hyaluronan and proteoglycan link protein 3
chr4_-_43640507 0.41 ENSDART00000150700
si:dkey-29p23.2
chr13_-_865193 0.41 ENSDART00000187053

chr15_+_618376 0.40 ENSDART00000156007
si:ch73-144d13.8
chr19_+_2279051 0.39 ENSDART00000182103
integrin, beta 8
chr21_+_45816030 0.39 ENSDART00000187056
paired-like homeodomain 1
chr16_-_33097398 0.39 ENSDART00000166617
dopey family member 1
chr8_-_410199 0.37 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr20_-_9760424 0.37 ENSDART00000104936
si:dkey-63j12.4
chr4_+_39055027 0.37 ENSDART00000150397
zinc finger protein 977
chr6_-_29049022 0.37 ENSDART00000190309
ecotropic viral integration site 5b
chr22_+_2239254 0.37 ENSDART00000131396
ENSDART00000135320
zinc finger protein 1144
chr20_-_3319642 0.37 ENSDART00000186743
ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr15_+_872085 0.37 ENSDART00000193867
ENSDART00000157483
ENSDART00000156324
si:dkey-7i4.9
si:dkey-77f5.13
si:dkey-7i4.11
chr18_-_20444296 0.37 ENSDART00000132993
kinesin family member 23
chr4_+_30775376 0.36 ENSDART00000158528
si:dkey-11d20.1
chr19_-_7225060 0.36 ENSDART00000133179
ENSDART00000151138
ENSDART00000104799
ENSDART00000128331
collagen, type XI, alpha 2
chr22_+_2254972 0.36 ENSDART00000144906
zinc finger protein 1157
chr8_-_24113575 0.36 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr21_-_5007109 0.35 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
ring finger protein 165a
chr15_+_879897 0.35 ENSDART00000185066
ENSDART00000179840
si:dkey-7i4.9
si:dkey-77f5.13
chr4_-_36144500 0.35 ENSDART00000170896
zinc finger protein 992
chr9_-_296169 0.35 ENSDART00000165228
kinesin family member 5A, a
chr25_-_6447835 0.34 ENSDART00000012820
snurportin 1
chr16_+_5184402 0.33 ENSDART00000156685
SOGA family member 3a
chr21_+_19547806 0.33 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
retinoic acid induced 14
chr4_+_40953320 0.33 ENSDART00000151912
zinc finger protein 1136
chr5_-_30145939 0.33 ENSDART00000086795
zinc finger and BTB domain containing 44
chr7_+_34549198 0.33 ENSDART00000173784
formin homology 2 domain containing 1
chr3_-_2593859 0.33 ENSDART00000143826
si:dkey-217f16.5
chr15_-_27710513 0.33 ENSDART00000005641
ENSDART00000134373
LIM homeobox 1a
chr22_+_1821718 0.32 ENSDART00000132220
zinc finger protein 1002
chr3_+_20156956 0.32 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr22_+_997838 0.32 ENSDART00000149743
peroxisome proliferator-activated receptor delta a
chr7_+_40228422 0.32 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr4_+_359970 0.32 ENSDART00000139832
transmembrane protein 181
chr16_-_41131578 0.32 ENSDART00000102649
ENSDART00000145956
protein tyrosine phosphatase, non-receptor type 23, a
chr9_-_28939181 0.31 ENSDART00000101276
ENSDART00000135334
erythrocyte membrane protein band 4.1 like 5
chr5_-_23999777 0.31 ENSDART00000085969
MAP7 domain containing 2a
chr7_+_24889783 0.31 ENSDART00000005329
ENSDART00000159955
MAP/microtubule affinity-regulating kinase 2b
chr13_+_28705143 0.31 ENSDART00000183338
LIM domain binding 1a
chr5_+_9047433 0.31 ENSDART00000091463
iduronidase, alpha-L-
chr4_-_73739119 0.30 ENSDART00000108669
zgc:171551
chr11_-_44163164 0.30 ENSDART00000047126
chloride channel, voltage-sensitive 4
chr20_-_54245256 0.30 ENSDART00000170482
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr4_-_6373735 0.30 ENSDART00000140100
si:ch73-156e19.1
chr9_+_7548533 0.30 ENSDART00000081543
protein tyrosine phosphatase, receptor type, Na
chr2_-_43739559 0.29 ENSDART00000138947
kinesin family member 5B, a
chr10_-_11353101 0.29 ENSDART00000092110
lin-54 DREAM MuvB core complex component
chr18_-_46063773 0.29 ENSDART00000078561
si:ch73-262h23.4
chr4_+_76304911 0.29 ENSDART00000172734
ENSDART00000161850
si:ch73-389k6.1
chr1_-_18592068 0.29 ENSDART00000082063
family with sequence similarity 114, member A1
chr24_-_41657005 0.29 ENSDART00000159109

chr25_+_16945348 0.28 ENSDART00000016591
fibroblast growth factor 6a
chr13_-_3155243 0.28 ENSDART00000139183
ENSDART00000050934
protein kinase domain containing, cytoplasmic a
chr5_-_19444930 0.28 ENSDART00000136259
ENSDART00000188499
potassium channel tetramerization domain containing 10
chr1_-_23596391 0.28 ENSDART00000155184
ligand dependent nuclear receptor corepressor-like
chr18_+_12058403 0.28 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicaudal D homolog 1a
chr1_-_11291324 0.28 ENSDART00000091205
sidekick cell adhesion molecule 1b
chr11_+_28166165 0.28 ENSDART00000169360
ENSDART00000192311
eph receptor B2b
chr12_-_10365875 0.28 ENSDART00000142386
ENSDART00000007335
NDC80 kinetochore complex component
chr8_+_1839695 0.28 ENSDART00000148254
ENSDART00000143473
synaptosomal-associated protein 29
chr5_-_32363372 0.28 ENSDART00000098045
growth arrest-specific 1b
chr15_-_5892650 0.28 ENSDART00000154812
bromodomain and WD repeat domain containing 1
chr25_-_6448050 0.27 ENSDART00000180616
snurportin 1
chr4_-_42294516 0.27 ENSDART00000133558
si:dkey-4e4.1
chr10_-_2971407 0.27 ENSDART00000132526
MARVEL domain containing 2a
chr17_-_24866727 0.27 ENSDART00000027957
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr21_-_44772738 0.27 ENSDART00000026178
kinesin family member 4
chr20_+_46699021 0.27 ENSDART00000167398
ENSDART00000029894
WD repeat domain 26b
chr4_-_73825089 0.27 ENSDART00000174207
si:dkey-262g12.12
chr22_+_2819613 0.27 ENSDART00000131234
si:dkey-20i20.3
chr1_-_17693273 0.26 ENSDART00000146258
cilia and flagella associated protein 97
chr4_-_43056627 0.26 ENSDART00000150269
si:dkey-54j5.2
chr9_-_6502491 0.26 ENSDART00000102672
NCK adaptor protein 2a
chr13_+_47623916 0.26 ENSDART00000109266
c-mer proto-oncogene tyrosine kinase a
chr1_+_19538299 0.26 ENSDART00000109416
structural maintenance of chromosomes 2
chr4_+_48769555 0.26 ENSDART00000150725
zinc finger protein 1020
chr5_+_22133153 0.25 ENSDART00000016214
moesin a
chr1_-_9940494 0.25 ENSDART00000138726
transmembrane protein 8A
chr4_+_76403698 0.25 ENSDART00000184821
ENSDART00000169373


chr15_+_1796313 0.25 ENSDART00000126253
family with sequence similarity 124B
chr4_+_45504471 0.24 ENSDART00000150399
si:dkey-256i11.2
chr15_+_17030473 0.24 ENSDART00000129407
perilipin 2
chr12_+_36109507 0.24 ENSDART00000175409
mitogen-activated protein kinase kinase 6
chr23_+_43424518 0.24 ENSDART00000022498
TELO2 interacting protein 1
chr4_+_65332578 0.24 ENSDART00000170824
zinc finger protein 1108
chr22_+_2228919 0.24 ENSDART00000133475
zinc finger protein 1161
chr17_-_32621103 0.24 ENSDART00000155321
XK related 5b
chr5_-_32882162 0.24 ENSDART00000085769
leucine rich repeat and sterile alpha motif containing 1
chr10_-_11353469 0.24 ENSDART00000191847
lin-54 DREAM MuvB core complex component
chr6_+_58832323 0.24 ENSDART00000042595
dynactin 2 (p50)
chr12_-_5455936 0.24 ENSDART00000109305
TBC1 domain family, member 12b
chr12_+_33894396 0.24 ENSDART00000130853
ENSDART00000152988
major facilitator superfamily domain containing 13A
chr4_-_149334 0.24 ENSDART00000163280
TANK-binding kinase 1
chr5_+_28259655 0.23 ENSDART00000087684
non-SMC condensin I complex, subunit H
chr25_+_34845469 0.23 ENSDART00000145416
transmembrane protein 231
chr1_-_38756870 0.23 ENSDART00000130324
ENSDART00000148404
glycoprotein M6Ab
chr13_+_22295905 0.23 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr15_-_762319 0.23 ENSDART00000154306
ENSDART00000157492
si:dkey-7i4.16
zinc finger protein 1011
chr2_-_30324610 0.23 ENSDART00000185422
junctophilin 1b
chr22_+_1947494 0.23 ENSDART00000159121
si:dkey-15h8.15
chr13_+_51710725 0.23 ENSDART00000163741
PWWP domain containing 2B
chr20_+_25911342 0.23 ENSDART00000146004
tau tubulin kinase 2b
chr22_-_18746508 0.23 ENSDART00000003929
midnolin
chr21_-_45086170 0.23 ENSDART00000188963
Rap guanine nucleotide exchange factor (GEF) 6
chr5_-_31856681 0.23 ENSDART00000187817
protein kinase N3
chr4_-_44801146 0.22 ENSDART00000154874
si:dkeyp-77c4.5
chr2_-_17115256 0.22 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr2_-_17114852 0.22 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr2_-_42415902 0.22 ENSDART00000142489
solute carrier organic anion transporter family member 5A1b
chr19_-_26923273 0.22 ENSDART00000089609
SKI2 homolog, superkiller viralicidic activity 2-like
chr4_-_48957129 0.22 ENSDART00000150426
zinc finger protein 1064
chr10_-_41906609 0.22 ENSDART00000102530
lysine (K)-specific demethylase 2Bb
chr21_-_43606502 0.22 ENSDART00000151030
si:ch73-362m14.4
chr5_+_51848756 0.22 ENSDART00000087467
ENSDART00000184466
cardiomyopathy associated 5
chr15_-_23443937 0.22 ENSDART00000148311
ubiquitination factor E4A (UFD2 homolog, yeast)
chr23_-_4409668 0.22 ENSDART00000081823
si:ch73-142c19.1
chr15_+_903743 0.21 ENSDART00000155783
si:dkey-77f5.13
chr21_+_45366229 0.21 ENSDART00000029946
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr25_-_32751982 0.21 ENSDART00000012862
ISL LIM homeobox 2a
chr11_-_575786 0.21 ENSDART00000019997
makorin, ring finger protein, 2
chr25_+_3104959 0.21 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr25_+_35683956 0.21 ENSDART00000149768
kinesin family member 21A
chr4_+_77076645 0.21 ENSDART00000174346

chr1_+_52792439 0.21 ENSDART00000123972
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr20_-_28352352 0.21 ENSDART00000128806
INO80 complex subunit
chr10_-_17170086 0.21 ENSDART00000020122
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr10_-_1276046 0.21 ENSDART00000169779
PDZ and LIM domain 5b
chr23_-_18981595 0.21 ENSDART00000147617
bcl2-like 1
chr15_+_618081 0.20 ENSDART00000181518
si:ch211-210b2.1
chr4_-_41825115 0.20 ENSDART00000160196
si:dkey-237m9.1
chr4_-_57869437 0.20 ENSDART00000170067
zgc:174314
chr16_-_32208728 0.20 ENSDART00000023995
calcium homeostasis modulator family member 5, tandem duplicate 2
chr2_-_10386738 0.20 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr5_-_41494831 0.20 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr21_-_435466 0.20 ENSDART00000110297
Kruppel-like factor 4
chr4_-_73448588 0.20 ENSDART00000138333
si:ch73-120g24.4
chr23_+_10805188 0.20 ENSDART00000035693
protein phosphatase 4, regulatory subunit 2a
chr9_-_370225 0.19 ENSDART00000163637
si:dkey-11f4.7
chr10_-_26273629 0.19 ENSDART00000147790
dachsous cadherin-related 1b
chr14_-_38946808 0.19 ENSDART00000139293
galactosidase, alpha
chr4_-_33405483 0.19 ENSDART00000150625

chr3_-_1204341 0.19 ENSDART00000089646
family with sequence similarity 234, member B
chr8_+_21406769 0.19 ENSDART00000135766
si:dkey-163f12.6
chr12_+_48204891 0.19 ENSDART00000190534
ENSDART00000164427
nodal-related 2
chr1_+_9290103 0.19 ENSDART00000055009
Unc4.1 homeobox (C. elegans)
chr2_-_43739740 0.19 ENSDART00000113849
kinesin family member 5B, a
chr15_-_780472 0.19 ENSDART00000188131
ENSDART00000156942
si:dkey-7i4.21
si:dkey-7i4.15
chr17_-_19345521 0.19 ENSDART00000082085
goosecoid
chr23_-_35396845 0.19 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cap methyltransferase 1
chr6_-_48311 0.19 ENSDART00000131010
zgc:114175
chr5_-_24000211 0.19 ENSDART00000188865
MAP7 domain containing 2a
chr4_-_30269748 0.18 ENSDART00000163550
si:dkey-233e3.3
chr1_-_55068941 0.18 ENSDART00000152143
ENSDART00000152590
pellino E3 ubiquitin protein ligase 1a
chr8_-_38317914 0.18 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr10_-_26274094 0.18 ENSDART00000108798
dachsous cadherin-related 1b
chr22_+_2660505 0.18 ENSDART00000135555
ENSDART00000031485
zinc finger protein 1162

Network of associatons between targets according to the STRING database.

First level regulatory network of atf2+atf7a+atf7b_creb5a+creb5b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 0.6 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 0.7 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.6 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.4 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.8 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.3 GO:0097377 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.1 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.3 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.4 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.2 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.1 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.2 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.2 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.3 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.0 0.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.1 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0003156 regulation of organ formation(GO:0003156)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 1.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0045176 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.2 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.8 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0016234 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.4 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0005035 death receptor activity(GO:0005035)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.0 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation