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PRJEB1986: zebrafish developmental stages transcriptome

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Results for arxa

Z-value: 0.52

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Transcription factors associated with arxa

Gene Symbol Gene ID Gene Info
ENSDARG00000058011 aristaless related homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arxadr11_v1_chr24_-_23942722_23942722-0.184.6e-01Click!

Activity profile of arxa motif

Sorted Z-values of arxa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_22320738 1.31 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr3_-_19368435 1.31 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr12_-_35830625 1.27 ENSDART00000180028

chr25_-_21031007 1.22 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr2_-_26596794 1.18 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr16_+_54209504 1.13 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr20_+_11731039 1.10 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
chr8_-_39822917 1.09 ENSDART00000067843
zgc:162025
chr23_-_42232124 1.07 ENSDART00000149944
glutathione peroxidase 7
chr3_-_26017831 1.07 ENSDART00000179982
heme oxygenase 1a
chr8_-_50888806 0.98 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr2_-_38284648 0.98 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
chr23_-_16485190 0.97 ENSDART00000155038
si:dkeyp-100a5.4
chr24_+_19415124 0.94 ENSDART00000186931
sulfatase 1
chr20_+_29209615 0.92 ENSDART00000062350
katanin p80 subunit B-like 1
chr25_+_30131055 0.91 ENSDART00000152705
apoptosis inhibitor 5
chr9_-_34937025 0.90 ENSDART00000137888
cell division cycle 16 homolog (S. cerevisiae)
chr24_-_38657683 0.88 ENSDART00000154843
si:ch1073-164k15.3
chr9_-_1986014 0.87 ENSDART00000142842
homeobox D12a
chr8_+_26059677 0.85 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr23_+_1029450 0.85 ENSDART00000189196
si:zfos-905g2.1
chr23_+_12134839 0.84 ENSDART00000128551
ENSDART00000141204
tubulin tyrosine ligase-like family, member 9
chr17_-_9950911 0.81 ENSDART00000105117
serine palmitoyltransferase, small subunit A
chr25_+_20715950 0.80 ENSDART00000180223
ERGIC and golgi 2
chr7_+_2969661 0.79 ENSDART00000158382

chr13_-_12602920 0.78 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr2_-_9989919 0.77 ENSDART00000180213
ENSDART00000184369
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr6_-_55399214 0.77 ENSDART00000168367
cathepsin A
chr16_-_7793457 0.77 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr21_+_43172506 0.74 ENSDART00000121725
zinc finger, CCHC domain containing 10
chr17_-_16422654 0.73 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr4_+_11723852 0.72 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr16_-_27677930 0.71 ENSDART00000145991
transforming growth factor beta regulator 4
chr19_-_5669122 0.71 ENSDART00000112211
si:ch211-264f5.2
chr22_-_36530902 0.70 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr22_-_5252005 0.70 ENSDART00000132942
ENSDART00000081801
nicalin
chr11_-_21528056 0.69 ENSDART00000181626
SLIT-ROBO Rho GTPase activating protein 2
chr25_+_11008419 0.68 ENSDART00000156589
major histocompatibility complex class I LIA
chr7_-_8712148 0.68 ENSDART00000065488
testis expressed 261
chr8_+_17167876 0.67 ENSDART00000134665
centromere protein H
chr3_+_30501135 0.67 ENSDART00000165869
si:dkey-13n23.3
chr11_-_39118882 0.65 ENSDART00000113185
ENSDART00000156526
adaptor-related protein complex 5, beta 1 subunit
chr16_+_23799622 0.65 ENSDART00000046922
RAB13, member RAS oncogene family
chr8_+_28259347 0.65 ENSDART00000110857
family with sequence similarity 212, member B
chr11_-_41853874 0.64 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr6_+_7533601 0.63 ENSDART00000057823
proliferation-associated 2G4, a
chr15_+_23799461 0.61 ENSDART00000154885
si:ch211-167j9.4
chr14_+_34558480 0.61 ENSDART00000075170
pituitary tumor-transforming 1
chr10_-_2788668 0.61 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr12_-_28363111 0.60 ENSDART00000016283
ENSDART00000164156
proteasome 26S subunit, non-ATPase 11b
chr8_+_49065348 0.60 ENSDART00000032277
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr2_-_10877765 0.60 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr5_-_54672763 0.59 ENSDART00000159009
sperm associated antigen 8
chr8_+_25079470 0.59 ENSDART00000000744
synaptophysin-like 2b
chr18_-_46258612 0.59 ENSDART00000153930
si:dkey-244a7.1
chr20_+_29209767 0.59 ENSDART00000141252
katanin p80 subunit B-like 1
chr15_-_4528326 0.58 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr2_+_10878406 0.57 ENSDART00000091497
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_+_21731382 0.56 ENSDART00000054395
paired box 5
chr13_-_31017960 0.56 ENSDART00000145287
WDFY family member 4
chr14_-_41388178 0.56 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr23_+_36460239 0.55 ENSDART00000172441
LIM domain and actin binding 1a
chr5_-_69649044 0.54 ENSDART00000011192
ENSDART00000170885
eukaryotic translation initiation factor 2B, subunit 1 alpha
chr3_+_40164129 0.54 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr7_-_5375214 0.54 ENSDART00000033316
VANGL planar cell polarity protein 2
chr4_-_9909371 0.53 ENSDART00000102656
si:dkey-22l11.6
chr4_+_19700308 0.52 ENSDART00000027919
paired box 4
chr21_+_6394929 0.52 ENSDART00000138600
si:ch211-225g23.1
chr18_+_39937225 0.52 ENSDART00000141136
si:ch211-282k23.2
chr2_-_45331115 0.51 ENSDART00000158003
si:dkey-13n23.3
chr23_-_36303216 0.51 ENSDART00000188720
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr20_+_25225112 0.51 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
monooxygenase, DBH-like 1
chr2_+_9990491 0.51 ENSDART00000011906
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr1_+_27977297 0.50 ENSDART00000180692
ENSDART00000166819
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr2_+_2169337 0.50 ENSDART00000179939
HIG1 hypoxia inducible domain family, member 1A
chr11_+_31324335 0.50 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr6_+_36839509 0.50 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr20_+_25586099 0.50 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr7_-_60156409 0.49 ENSDART00000006802
chaperonin containing TCP1, subunit 7 (eta)
chr17_-_29224908 0.49 ENSDART00000156288
si:dkey-28g23.6
chr1_-_45616470 0.49 ENSDART00000150165
activating transcription factor 7 interacting protein
chr21_-_15200556 0.48 ENSDART00000141809
splicing factor SWAP
chr9_-_11676491 0.48 ENSDART00000022358
zinc finger CCCH-type containing 15
chr10_+_26652859 0.48 ENSDART00000079174
HIV-1 Tat specific factor 1
chr14_+_5385855 0.47 ENSDART00000031508
ladybird homeobox 2
chr25_+_7241084 0.47 ENSDART00000190501
ENSDART00000190588
high mobility group 20A
chr20_+_29209926 0.47 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr8_+_18011522 0.47 ENSDART00000136756
single stranded DNA binding protein 3b
chr25_-_28674739 0.46 ENSDART00000067073
leucine rich repeat containing 10
chr19_+_2631565 0.46 ENSDART00000171487
family with sequence similarity 126, member A
chr16_-_30434279 0.46 ENSDART00000018504
zgc:77086
chr21_+_43328685 0.45 ENSDART00000109620
ENSDART00000139668
septin 8a
chr10_+_42521943 0.45 ENSDART00000010420
ENSDART00000075303
ARP1 actin related protein 1, centractin
chr6_-_40922971 0.44 ENSDART00000155363
SFI1 centrin binding protein
chr14_-_5817039 0.43 ENSDART00000131820
Kazal-type serine peptidase inhibitor domain 2
chr11_+_16153207 0.43 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr12_-_36521767 0.42 ENSDART00000110290
unc-13 homolog D (C. elegans)
chr6_+_40922572 0.42 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr23_+_4709607 0.42 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr23_-_33350990 0.42 ENSDART00000144831
si:ch211-226m16.2
chr7_+_24023653 0.42 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_42955280 0.42 ENSDART00000141225
fatty acid binding protein 3, muscle and heart
chr10_-_3138859 0.41 ENSDART00000190606
ubiquitin-conjugating enzyme E2L 3a
chr10_-_3138403 0.40 ENSDART00000183365
ubiquitin-conjugating enzyme E2L 3a
chr18_+_39106722 0.40 ENSDART00000122377
BCL2 like 10
chr7_-_51368681 0.40 ENSDART00000146385
Rho GTPase activating protein 36
chr6_+_25261297 0.40 ENSDART00000162824
ENSDART00000163490
ENSDART00000157790
ENSDART00000160978
ENSDART00000161545
ENSDART00000159978
kynurenine aminotransferase 3
chr23_+_29885019 0.40 ENSDART00000167059
aurora kinase A interacting protein 1
chr5_+_32076109 0.39 ENSDART00000051357
ENSDART00000144510
zinc finger, matrin-type 5
chr7_+_19495905 0.39 ENSDART00000125584
ENSDART00000173774
si:ch211-212k18.8
chr6_-_7720332 0.38 ENSDART00000135945
ribosomal protein SA
chr15_-_35098345 0.37 ENSDART00000181824

chr11_-_16152400 0.37 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr12_-_48188928 0.37 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr5_+_66433287 0.36 ENSDART00000170757
kinetochore associated 1
chr5_-_52010122 0.35 ENSDART00000073627
ENSDART00000163898
ENSDART00000051003
cyclin-dependent kinase 7
chr11_+_31323746 0.35 ENSDART00000180220
ENSDART00000189937
signal-induced proliferation-associated 1 like 2
chr14_+_30568961 0.35 ENSDART00000184303
mitochondrial ribosomal protein L11
chr9_-_30555725 0.35 ENSDART00000079222
chromatin assembly factor 1, subunit B
chr24_+_38301080 0.34 ENSDART00000105672
myosin binding protein C, fast type b
chr7_-_30677104 0.34 ENSDART00000188360
myosin IE, a
chr24_+_29912509 0.34 ENSDART00000168422
ferric-chelate reductase 1b
chr11_+_16152316 0.33 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr13_-_35808904 0.33 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr8_-_53044300 0.32 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr17_-_10122204 0.32 ENSDART00000160751

chr22_+_11775269 0.31 ENSDART00000140272
keratin 96
chr21_-_30082414 0.31 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr2_-_59205393 0.30 ENSDART00000056417
ENSDART00000182452
ENSDART00000141876
finTRIM family, member 30
chr4_-_1801519 0.30 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr3_-_34052882 0.30 ENSDART00000151463
immunoglobulin heavy variable 11-1
chr9_-_41062412 0.30 ENSDART00000193879
ankyrin and armadillo repeat containing
chr3_+_27798094 0.30 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr9_+_43799829 0.30 ENSDART00000186240
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr3_-_34034498 0.29 ENSDART00000151145
immunoglobulin heavy variable 11-2
chr1_+_47499888 0.28 ENSDART00000027624
STN1, CST complex subunit
chr18_+_7073130 0.28 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr7_-_50410524 0.28 ENSDART00000083346
huntingtin interacting protein K
chr3_-_26787430 0.28 ENSDART00000087047
RAB40c, member RAS oncogene family
chr13_-_4707018 0.27 ENSDART00000128422
oncoprotein induced transcript 3
chr17_+_20589553 0.26 ENSDART00000154447
si:ch73-288o11.4
chr2_-_17392799 0.26 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr7_+_21272833 0.25 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr23_-_30041065 0.25 ENSDART00000131209
ENSDART00000127192
coiled-coil domain containing 187
chr19_-_10810006 0.25 ENSDART00000151157
si:dkey-3n22.9
chr20_-_37813863 0.25 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr16_+_23984179 0.24 ENSDART00000175879
apolipoprotein C-II
chr12_-_4185554 0.24 ENSDART00000152313
si:dkey-32n7.7
chr20_-_51355465 0.24 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
t-complex-associated-testis-expressed 1
chr11_-_1509773 0.24 ENSDART00000050762
phosphatase and actin regulator 3b
chr5_+_40485503 0.24 ENSDART00000051055
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr8_+_18615938 0.24 ENSDART00000089161
si:ch211-232d19.4
chr20_+_40457599 0.23 ENSDART00000017553
serine incorporator 1
chr13_-_36798204 0.23 ENSDART00000012357
salvador family WW domain containing protein 1
chr21_+_13387965 0.23 ENSDART00000134347
zgc:113162
chr19_+_43780970 0.22 ENSDART00000063870
ribosomal protein L11
chr10_+_38610741 0.22 ENSDART00000126444
matrix metallopeptidase 13a
chr1_-_19502322 0.22 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr2_+_11923615 0.22 ENSDART00000126118
TROVE domain family, member 2
chr23_-_31969786 0.21 ENSDART00000134550
ORMDL sphingolipid biosynthesis regulator 2
chr10_-_43771447 0.21 ENSDART00000052307
arrestin domain containing 3b
chr21_-_4793686 0.21 ENSDART00000158232
notch 1a
chr4_-_45115963 0.20 ENSDART00000137248
si:dkey-51d8.6
chr24_+_35787629 0.20 ENSDART00000136721
si:dkeyp-7a3.1
chr6_+_12527725 0.20 ENSDART00000149328
serine/threonine kinase 24b (STE20 homolog, yeast)
chr6_+_49551614 0.20 ENSDART00000022581
RAB22A, member RAS oncogene family
chr21_+_45223194 0.19 ENSDART00000150902
si:ch73-269m14.3
chr5_-_11809710 0.19 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr2_+_1988036 0.19 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr24_+_37640626 0.19 ENSDART00000008047
WD repeat domain 24
chr9_+_22351443 0.19 ENSDART00000080054
crystallin, gamma S3
chr5_+_24156170 0.19 ENSDART00000136570
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr5_+_33498253 0.19 ENSDART00000140993
membrane-spanning 4-domains, subfamily A, member 17c.2
chr21_-_45363871 0.18 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
zgc:56064
chr7_+_26173751 0.17 ENSDART00000065131
si:ch211-196f2.7
chr6_+_8598428 0.17 ENSDART00000032118
ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
chr20_-_51831816 0.17 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr4_-_69428110 0.17 ENSDART00000160607
si:ch211-145h19.3
chr24_-_37640705 0.17 ENSDART00000066583
zgc:112496
chr7_+_19495379 0.17 ENSDART00000180514
si:ch211-212k18.8
chr20_+_38458084 0.16 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr8_-_51930826 0.16 ENSDART00000109785
calcineurin binding protein 1
chr7_+_22543963 0.16 ENSDART00000101528
cholinergic receptor, nicotinic, beta 1 (muscle)
chr14_-_470505 0.15 ENSDART00000067147
ankyrin repeat domain 50
chr16_+_13818743 0.15 ENSDART00000090191
folliculin
chr10_+_34010494 0.15 ENSDART00000186836
ENSDART00000114703
klotho
chr20_+_22799857 0.15 ENSDART00000058527
sec1 family domain containing 2
chr21_-_19314618 0.15 ENSDART00000188744
glycerol-3-phosphate acyltransferase 3
chr7_+_34453185 0.15 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
chr3_+_32118670 0.15 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr16_+_35379720 0.15 ENSDART00000170497
si:dkey-34d22.2
chr2_-_17393216 0.14 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr4_-_5108844 0.14 ENSDART00000132666
ENSDART00000136096
transmembrane protein 209
chr18_+_17827149 0.14 ENSDART00000190237
ENSDART00000189345
si:ch211-216l23.1
chr20_+_20731633 0.14 ENSDART00000191952
ENSDART00000165224
protein phosphatase 1, regulatory subunit 13Bb
chr13_+_7049823 0.14 ENSDART00000178997
ENSDART00000161443
ribonuclease T2
chr3_+_32365811 0.14 ENSDART00000155967
adaptor-related protein complex 2, alpha 1 subunit
chr15_-_21014270 0.13 ENSDART00000154019
si:ch211-212c13.10
chr2_+_35806672 0.13 ENSDART00000137384
RAS protein activator like 2
chr22_+_737211 0.13 ENSDART00000017305
zinc finger protein 76

Network of associatons between targets according to the STRING database.

First level regulatory network of arxa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0000012 single strand break repair(GO:0000012)
0.4 1.1 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.3 1.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.5 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.1 GO:0097065 anterior head development(GO:0097065)
0.2 0.7 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.5 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.2 0.8 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.7 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.9 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.9 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.5 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.6 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.2 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.6 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.2 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0051279 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.0 1.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.5 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.5 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0050821 protein stabilization(GO:0050821)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0033046 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.8 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0016233 telomere capping(GO:0016233)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.7 GO:0045335 dendritic spine head(GO:0044327) phagocytic vesicle(GO:0045335)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 0.7 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.8 GO:0035198 miRNA binding(GO:0035198)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.8 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo