Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for arnt2

Z-value: 2.17

Motif logo

Transcription factors associated with arnt2

Gene Symbol Gene ID Gene Info
ENSDARG00000103697 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arnt2dr11_v1_chr7_+_10701938_107019380.643.0e-03Click!

Activity profile of arnt2 motif

Sorted Z-values of arnt2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_46313135 8.67 ENSDART00000172902
crystallin, beta A1, like 1
chr7_-_74090168 8.50 ENSDART00000050528
tyrosinase-related protein 1a
chr14_+_46313396 8.35 ENSDART00000047525
crystallin, beta A1, like 1
chr5_-_23429228 7.88 ENSDART00000049291
glutamate receptor, ionotropic, AMPA 3a
chr23_-_6641223 7.50 ENSDART00000023793
major intrinsic protein of lens fiber b
chr5_+_55626693 5.54 ENSDART00000168908
ENSDART00000161412
neurotrophic tyrosine kinase, receptor, type 2b
chr17_+_10566490 5.53 ENSDART00000144408
ENSDART00000137469
MGA, MAX dimerization protein a
chr12_-_22540943 5.10 ENSDART00000172310
zinc finger and BTB domain containing 4
chr21_+_30194904 4.52 ENSDART00000137023
ENSDART00000078403
si:ch211-59d17.3
chr11_+_7324704 4.38 ENSDART00000031937
DIRAS family, GTP-binding RAS-like 1a
chr5_+_32162684 4.33 ENSDART00000134472
TAO kinase 3b
chr20_+_35382482 4.25 ENSDART00000135284
visinin-like 1a
chr5_+_36932718 4.23 ENSDART00000037879
cone-rod homeobox
chr21_+_6751405 4.19 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr5_+_23118470 4.18 ENSDART00000149893
neurite extension and migration factor a
chr13_+_27314795 4.17 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr11_+_30513656 4.14 ENSDART00000008594
transmembrane protein 178
chr24_-_11325849 4.07 ENSDART00000182485
myosin VIIA and Rab interacting protein
chr10_+_29963518 3.82 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
neurotrimin
chr20_-_47731768 3.73 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr1_+_14283692 3.67 ENSDART00000017679
protein phosphatase 2, regulatory subunit B, gamma a
chr14_+_41409697 3.66 ENSDART00000173335
BCL6 corepressor-like 1
chr2_+_49522178 3.59 ENSDART00000056254
signal transducing adaptor family member 2a
chr17_-_17447899 3.59 ENSDART00000156928
ENSDART00000109034
neurexin 3a
chr2_+_42724404 3.52 ENSDART00000075392
brain abundant, membrane attached signal protein 1
chr5_+_36611128 3.46 ENSDART00000097684
neuro-oncological ventral antigen 1
chr18_-_46208581 3.45 ENSDART00000141278
si:ch211-14c7.2
chr15_-_34418525 3.36 ENSDART00000147582
alkylglycerol monooxygenase
chr15_+_38859648 3.31 ENSDART00000141086
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr15_-_12319065 3.27 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr11_-_24428237 3.20 ENSDART00000189107
ENSDART00000103752
dishevelled segment polarity protein 1b
chr11_+_36989696 3.17 ENSDART00000045888
transketolase a
chr1_-_22757145 3.14 ENSDART00000134719
prominin 1 b
chr12_+_35119762 3.13 ENSDART00000085774
si:ch73-127m5.1
chr7_-_38340674 3.12 ENSDART00000075782
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr23_-_8373676 3.04 ENSDART00000105135
ENSDART00000158531
opiate receptor-like 1
chr21_+_6751760 3.04 ENSDART00000135914
olfactomedin 1b
chr4_+_9279784 3.04 ENSDART00000014897
SLIT-ROBO Rho GTPase activating protein 1b
chr6_-_39006449 3.00 ENSDART00000150885
vitamin D receptor b
chr17_-_22067451 2.91 ENSDART00000156872
tau tubulin kinase 1b
chr25_+_13406069 2.90 ENSDART00000010495
zinc and ring finger 1
chr20_-_8419057 2.84 ENSDART00000145841
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr1_+_42225060 2.84 ENSDART00000138740
ENSDART00000101306
catenin (cadherin-associated protein), alpha 2
chr5_-_16983336 2.83 ENSDART00000038740
polypeptide N-acetylgalactosaminyltransferase 9
chr21_+_6212844 2.82 ENSDART00000150301
formin binding protein 1b
chr23_+_17220986 2.73 ENSDART00000054761
nucleolar protein 4-like b
chr21_-_14630831 2.73 ENSDART00000132142
ENSDART00000089967
calcium channel, voltage-dependent, N type, alpha 1B subunit, b
chr13_-_3516473 2.72 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr8_-_18899427 2.71 ENSDART00000079840
RAR-related orphan receptor C a
chr15_+_36156986 2.69 ENSDART00000059791
somatostatin 1, tandem duplicate 1
chr23_-_16692312 2.67 ENSDART00000046784
FK506 binding protein 1Ab
chr21_+_28958471 2.63 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr21_+_5169154 2.59 ENSDART00000102559
zgc:122979
chr6_+_4872883 2.57 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
protocadherin 9
chr16_-_13388821 2.57 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr1_-_22512063 2.57 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr3_+_14768364 2.55 ENSDART00000090235
ENSDART00000139001
nuclear factor I/Xb
chr19_+_17259912 2.55 ENSDART00000078951
si:ch211-30b16.2
chr25_+_19954576 2.49 ENSDART00000149335
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr7_+_10701938 2.48 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr1_-_19237576 2.45 ENSDART00000143663
ENSDART00000131579
protein tyrosine phosphatase, receptor type, D, b
chr19_+_49721 2.43 ENSDART00000160489
collagen, type XIV, alpha 1b
chr1_-_8917902 2.42 ENSDART00000137900
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr19_-_10243148 2.40 ENSDART00000148073
shisa family member 7
chr5_-_22952156 2.39 ENSDART00000111146
si:ch211-26b3.4
chr18_+_49411417 2.33 ENSDART00000028944
zmp:0000001073
chr17_+_9310259 2.32 ENSDART00000186158
ENSDART00000190329
neuronal PAS domain protein 3
chr9_-_23217196 2.32 ENSDART00000083567
kinesin family member 5C
chr19_+_15571290 2.32 ENSDART00000131134
forkhead box O6 b
chr19_-_1023051 2.27 ENSDART00000158429
transmembrane protein 42b
chr5_-_32092856 2.26 ENSDART00000086181
ENSDART00000181677
calcium binding protein 7b
chr13_+_24022963 2.25 ENSDART00000028285
piggyBac transposable element derived 5
chr1_+_36436936 2.24 ENSDART00000124112
POU class 4 homeobox 2
chr14_+_8275115 2.24 ENSDART00000129055
neuregulin 2b
chr11_+_41135055 2.21 ENSDART00000173252
calmodulin binding transcription activator 1
chr6_-_26559921 2.21 ENSDART00000104532
SRY (sex determining region Y)-box 14
chr17_-_20287530 2.19 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr19_+_48176745 2.19 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr21_+_6780340 2.18 ENSDART00000139493
ENSDART00000140478
olfactomedin 1b
chr14_-_47314340 2.17 ENSDART00000164851
follistatin-like 5
chr6_-_14292307 2.16 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr2_-_24603325 2.16 ENSDART00000113356
CREB regulated transcription coactivator 1a
chr1_+_33969015 2.16 ENSDART00000042984
ENSDART00000146530
eph receptor A6
chr16_+_10918252 2.15 ENSDART00000172949
POU class 2 homeobox 2a
chr18_-_33344 2.15 ENSDART00000129125
phosphodiesterase 8A
chr11_-_36963988 2.14 ENSDART00000168288
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr1_-_22756898 2.11 ENSDART00000158915
prominin 1 b
chr8_+_1082100 2.05 ENSDART00000149276
leucine zipper, putative tumor suppressor family member 3b
chr13_+_12299997 2.00 ENSDART00000108535
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr3_+_18097700 1.98 ENSDART00000021634
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr1_-_18446161 1.98 ENSDART00000089442
kelch-like family member 5
chr7_-_44963154 1.96 ENSDART00000073735
Ras-related associated with diabetes
chr9_-_44295071 1.95 ENSDART00000011837
neuronal differentiation 1
chr15_-_12229874 1.95 ENSDART00000165159
Down syndrome cell adhesion molecule like 1
chr22_-_14128716 1.95 ENSDART00000140323
si:ch211-246m6.4
chr11_-_37589293 1.93 ENSDART00000172989
bassoon (presynaptic cytomatrix protein) b
chr4_-_4780667 1.92 ENSDART00000133973
si:ch211-258f14.2
chr23_-_12158685 1.90 ENSDART00000135035
family with sequence similarity 217, member B
chr19_-_205104 1.90 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr8_+_10561922 1.89 ENSDART00000133348
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5-like
chr19_+_10396042 1.87 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr11_-_3959477 1.87 ENSDART00000045971
polybromo 1
chr12_-_431249 1.83 ENSDART00000083827
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr20_+_826459 1.81 ENSDART00000104740
5'-nucleotidase, ecto (CD73)
chr12_+_9703172 1.79 ENSDART00000091489
protein phosphatase 1, regulatory subunit 9Bb
chr14_-_7885707 1.78 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr11_+_30161699 1.78 ENSDART00000190504
cyclin-dependent kinase-like 5
chr13_-_30027730 1.78 ENSDART00000044009
stearoyl-CoA desaturase b
chr7_+_25858380 1.76 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr2_+_21090317 1.75 ENSDART00000109568
ENSDART00000139633
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr11_+_34824099 1.70 ENSDART00000037017
ENSDART00000146944
solute carrier family 38, member 3a
chr2_+_47581997 1.70 ENSDART00000112579
secretogranin II (chromogranin C), b
chr1_-_7917062 1.69 ENSDART00000177068
monocyte to macrophage differentiation-associated 2b
chr16_-_33059246 1.67 ENSDART00000171718
ENSDART00000168305
ENSDART00000166401
synaptosomal-associated protein 91
chr11_+_30161168 1.66 ENSDART00000157385
cyclin-dependent kinase-like 5
chr8_-_23328264 1.66 ENSDART00000131934
nucleolar protein 4-like a
chr15_-_28247583 1.66 ENSDART00000112967
Rab interacting lysosomal protein
chr17_+_28340138 1.65 ENSDART00000033943
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr5_-_71460556 1.64 ENSDART00000108804
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr22_-_29191152 1.64 ENSDART00000132702
parvalbumin 7
chr16_-_13662514 1.64 ENSDART00000146348
shisa family member 7a
chr4_-_27350820 1.63 ENSDART00000145806
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr3_+_17744339 1.62 ENSDART00000132622
zinc finger protein 385C
chr6_+_11829867 1.62 ENSDART00000151044
bromodomain adjacent to zinc finger domain, 2Ba
chr4_-_4706893 1.61 ENSDART00000093005

chr24_-_38110779 1.61 ENSDART00000147783
c-reactive protein, pentraxin-related
chr24_-_18179535 1.60 ENSDART00000186112
contactin associated protein like 2a
chr24_-_3419998 1.59 ENSDART00000066839
solute carrier family 35, member G2b
chr19_+_33732188 1.59 ENSDART00000151192
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_2682198 1.58 ENSDART00000183727
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr25_+_4541211 1.55 ENSDART00000129978
patatin-like phospholipase domain containing 2
chr19_+_42660158 1.55 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr5_+_3501859 1.54 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr3_-_3496738 1.54 ENSDART00000186849

chr6_-_58910402 1.53 ENSDART00000156662
methyl-CpG binding domain protein 6
chr8_-_11640240 1.53 ENSDART00000091752
formin binding protein 1a
chr22_-_21150845 1.53 ENSDART00000027345
transmembrane protein 59-like
chr16_+_1802307 1.52 ENSDART00000180026
glutamate ionotropic receptor kainate type subunit 2
chr1_+_8662530 1.52 ENSDART00000054989
fascin actin-bundling protein 1b
chr1_+_31942961 1.50 ENSDART00000007522
anosmin 1a
chr2_+_25929619 1.50 ENSDART00000137746
solute carrier family 7, member 14a
chr1_+_42224769 1.50 ENSDART00000177496
ENSDART00000184778
ENSDART00000110860
catenin (cadherin-associated protein), alpha 2
chr4_+_7888047 1.49 ENSDART00000104676
calcium/calmodulin-dependent protein kinase 1Da
chr4_-_2867461 1.49 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr21_-_27185915 1.49 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr19_-_10395683 1.48 ENSDART00000109488
zgc:194578
chr15_-_33734105 1.48 ENSDART00000172729
ENSDART00000172045
tRNA methyltransferase 9B
chr10_-_15053507 1.48 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr1_-_45633955 1.47 ENSDART00000044057
septin 3
chr6_+_40992409 1.45 ENSDART00000151419
transforming growth factor, alpha
chr5_-_28915130 1.44 ENSDART00000078592
neural proliferation, differentiation and control, 1b
chr16_-_12953739 1.44 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr13_-_17464362 1.43 ENSDART00000145499
leucine rich melanocyte differentiation associated
chr4_+_10888762 1.43 ENSDART00000136049
synaptotagmin X
chr19_-_47452874 1.42 ENSDART00000025931
transcription factor AP-2 epsilon
chr8_+_20624510 1.42 ENSDART00000138604
nuclear factor I/C
chr21_-_41305748 1.41 ENSDART00000170457
neuronal vesicle trafficking associated 2
chr8_+_44623540 1.40 ENSDART00000141513
G protein-coupled receptor kinase 5 like
chr23_-_44494401 1.40 ENSDART00000114640
ENSDART00000148532
actin-like 6B
chr11_+_34824262 1.38 ENSDART00000103157
solute carrier family 38, member 3a
chr12_-_25150239 1.38 ENSDART00000038415
ENSDART00000135368
ras homolog family member Q
chr13_-_32648382 1.37 ENSDART00000138571
ENSDART00000132820
BEN domain containing 3
chr3_-_62380146 1.36 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr13_-_31166544 1.36 ENSDART00000146250
ENSDART00000132129
ENSDART00000139591
mitogen-activated protein kinase 8a
chr10_+_36650222 1.34 ENSDART00000126963
uncoupling protein 3
chr13_+_12739283 1.34 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr24_+_35881984 1.34 ENSDART00000066587
kelch-like family member 14
chr12_-_14922955 1.33 ENSDART00000002078
neurogenic differentiation 2
chr25_-_36282539 1.32 ENSDART00000073398
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10b
chr3_+_46628885 1.32 ENSDART00000006602
phosphodiesterase 4A, cAMP-specific
chr4_+_121709 1.32 ENSDART00000186461
ENSDART00000172255
cAMP responsive element binding protein-like 2
chr7_-_33949246 1.32 ENSDART00000173513
protein inhibitor of activated STAT, 1a
chr23_-_31555696 1.31 ENSDART00000053539
transcription factor 21
chr17_-_45552602 1.31 ENSDART00000154844
ENSDART00000034432
sushi domain containing 4
chr4_-_4780510 1.30 ENSDART00000109609
si:ch211-258f14.2
chr23_+_22656477 1.30 ENSDART00000009337
ENSDART00000133322
enolase 1a, (alpha)
chr5_-_48285756 1.29 ENSDART00000183495
myocyte enhancer factor 2cb
chr25_-_32311048 1.29 ENSDART00000181806
ENSDART00000086334

chr13_-_17464654 1.28 ENSDART00000140312
leucine rich melanocyte differentiation associated
chr17_+_22530820 1.28 ENSDART00000089916
EDAR-associated death domain
chr18_-_44610992 1.28 ENSDART00000125968
ENSDART00000185836
sprouty-related, EVH1 domain containing 3
chr21_-_435466 1.28 ENSDART00000110297
Kruppel-like factor 4
chr22_-_11054244 1.28 ENSDART00000105823
insulin receptor b
chr15_-_43978141 1.27 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr20_-_2949028 1.26 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cyclin-dependent kinase 19
chr23_+_35847200 1.26 ENSDART00000129222
retinoic acid receptor gamma a
chr13_-_20518632 1.24 ENSDART00000165310
gdnf family receptor alpha 1a
chr14_-_34276574 1.23 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr7_-_56793739 1.22 ENSDART00000082842
si:ch211-146m13.3
chr21_-_10446405 1.22 ENSDART00000167948
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr17_+_52823015 1.21 ENSDART00000160507
ENSDART00000186979
Meis homeobox 2a
chr21_+_23953181 1.21 ENSDART00000145541
ENSDART00000065599
ENSDART00000112869
cell adhesion molecule 1a
chr16_-_44127307 1.20 ENSDART00000104583
ENSDART00000151936
ENSDART00000058685
ENSDART00000190830
zinc finger protein, FOG family member 2a
chr4_-_6567355 1.20 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr19_+_33732487 1.20 ENSDART00000010294
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_28482862 1.19 ENSDART00000015286
ENSDART00000154320
ankyrin repeat domain 13B
chr10_-_15919839 1.18 ENSDART00000065032
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr11_+_6152643 1.18 ENSDART00000012789
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr19_-_42651615 1.18 ENSDART00000123360
sushi domain containing 5
chr8_-_21184759 1.18 ENSDART00000139257
glutaminase 2a (liver, mitochondrial)

Network of associatons between targets according to the STRING database.

First level regulatory network of arnt2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.7 5.1 GO:0060031 mediolateral intercalation(GO:0060031)
1.5 4.4 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
1.4 4.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.1 4.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
1.0 4.2 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.9 8.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.9 4.4 GO:0061551 trigeminal ganglion development(GO:0061551)
0.8 7.5 GO:0006833 water transport(GO:0006833)
0.8 3.1 GO:0006867 asparagine transport(GO:0006867)
0.7 3.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.6 3.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.6 1.7 GO:0021611 facial nerve formation(GO:0021611)
0.5 1.5 GO:0042044 fluid transport(GO:0042044)
0.5 1.4 GO:0006972 hyperosmotic response(GO:0006972)
0.5 3.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.5 3.2 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 4.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 1.8 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 1.3 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.4 1.3 GO:2000257 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.4 1.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.6 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4 0.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.4 2.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.5 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.4 3.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 5.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.4 1.8 GO:0051701 interaction with host(GO:0051701)
0.4 2.8 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.4 1.8 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.3 1.4 GO:0046324 regulation of glucose import(GO:0046324)
0.3 1.3 GO:0060074 synapse maturation(GO:0060074)
0.3 2.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.3 3.3 GO:0050975 sensory perception of touch(GO:0050975)
0.3 1.6 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.3 1.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 1.8 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.3 5.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.3 0.9 GO:0071314 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.3 1.2 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.3 1.1 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.3 1.0 GO:0015677 copper ion import(GO:0015677)
0.3 0.5 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.3 2.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 2.5 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.2 1.0 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.2 3.0 GO:0019233 sensory perception of pain(GO:0019233)
0.2 2.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 1.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 2.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 1.3 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 2.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 0.6 GO:0015874 norepinephrine transport(GO:0015874)
0.2 6.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 1.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 0.8 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.2 0.6 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 0.5 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 5.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 2.8 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 1.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 3.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 1.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 1.1 GO:0002931 response to ischemia(GO:0002931)
0.2 1.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.8 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.2 1.4 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.2 0.8 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 3.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.2 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 2.4 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.1 17.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.8 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.8 GO:0021767 mammillary body development(GO:0021767)
0.1 0.9 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 1.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 4.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.5 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.8 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 1.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.6 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 2.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.4 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.9 GO:0001881 receptor recycling(GO:0001881)
0.1 4.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 3.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.4 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 0.9 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.0 GO:0030431 sleep(GO:0030431)
0.1 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 3.0 GO:0060037 pharyngeal system development(GO:0060037)
0.1 4.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.3 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 1.2 GO:0045471 response to ethanol(GO:0045471)
0.1 1.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.6 GO:0042461 photoreceptor cell development(GO:0042461)
0.1 1.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 4.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 1.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.5 GO:1990798 pancreas regeneration(GO:1990798)
0.1 3.3 GO:0071599 otic vesicle development(GO:0071599)
0.1 1.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.7 GO:0032196 transposition(GO:0032196)
0.1 0.6 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 1.3 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 2.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.7 GO:0019835 cytolysis(GO:0019835)
0.1 0.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.0 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.5 GO:0010890 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.1 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.4 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 2.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 1.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.2 GO:0031638 zymogen activation(GO:0031638)
0.0 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.8 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 2.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.4 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0036314 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 2.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.2 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 1.0 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 1.3 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 1.7 GO:0006414 translational elongation(GO:0006414)
0.0 1.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.0 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 5.5 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 2.3 GO:0006865 amino acid transport(GO:0006865)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 2.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.4 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 2.2 GO:0048511 rhythmic process(GO:0048511)
0.0 0.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 5.2 GO:0006897 endocytosis(GO:0006897)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0015908 fatty acid transport(GO:0015908)
0.0 1.3 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.7 4.4 GO:0005955 calcineurin complex(GO:0005955)
0.7 8.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.7 5.2 GO:0071914 prominosome(GO:0071914)
0.5 1.5 GO:0010369 chromocenter(GO:0010369)
0.4 5.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 16.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 3.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 1.3 GO:0005899 insulin receptor complex(GO:0005899)
0.3 2.8 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 2.5 GO:0033270 paranode region of axon(GO:0033270)
0.2 1.9 GO:0016586 RSC complex(GO:0016586)
0.2 5.5 GO:0071141 SMAD protein complex(GO:0071141)
0.2 1.4 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.6 GO:0033010 paranodal junction(GO:0033010)
0.2 1.9 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0043291 RAVE complex(GO:0043291)
0.1 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 3.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 4.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.7 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.7 GO:0030426 growth cone(GO:0030426)
0.1 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 17.3 GO:0030424 axon(GO:0030424)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 3.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.5 GO:0070382 exocytic vesicle(GO:0070382) secretory vesicle(GO:0099503)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.5 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.8 7.5 GO:0015250 water channel activity(GO:0015250)
0.7 4.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.6 9.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 3.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 3.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.5 3.1 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.5 3.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 2.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.4 3.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.4 3.3 GO:0004985 opioid receptor activity(GO:0004985)
0.3 1.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.3 GO:0071253 connexin binding(GO:0071253)
0.3 6.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 2.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 0.9 GO:0016496 substance P receptor activity(GO:0016496)
0.3 1.0 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.3 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 2.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 17.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.6 GO:0005330 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.2 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 5.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.6 GO:0031704 apelin receptor binding(GO:0031704)
0.2 4.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.9 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 4.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.8 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.2 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 1.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 1.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 7.1 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.2 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 4.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 9.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 2.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.8 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 2.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.6 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 3.0 GO:0019003 GDP binding(GO:0019003)
0.1 1.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 2.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.0 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.2 GO:0017022 myosin binding(GO:0017022)
0.1 1.2 GO:0005272 sodium channel activity(GO:0005272)
0.1 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.6 GO:0051087 chaperone binding(GO:0051087)
0.1 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 2.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 3.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.3 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.0 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 1.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 3.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.5 GO:0000049 tRNA binding(GO:0000049)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 2.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.4 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.0 GO:0046332 SMAD binding(GO:0046332)
0.0 1.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0008146 sulfotransferase activity(GO:0008146)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 2.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 1.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 4.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 1.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis