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PRJEB1986: zebrafish developmental stages transcriptome

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Results for arid5b

Z-value: 0.40

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Transcription factors associated with arid5b

Gene Symbol Gene ID Gene Info
arid5b
ENSDARG00000037196 AT-rich interaction domain 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid5bdr11_v1_chr12_+_8168272_81682720.512.5e-02Click!

Activity profile of arid5b motif

Sorted Z-values of arid5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_21832441 1.03 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
mbpa
myelin basic protein a
chr3_+_19299309 0.92 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr22_+_19311411 0.91 ENSDART00000133234
ENSDART00000138284
si:dkey-21e2.16
si:dkey-21e2.16
chr18_+_5543677 0.89 ENSDART00000146161
ENSDART00000136189
nnt2
nicotinamide nucleotide transhydrogenase 2
chr9_+_5862040 0.85 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr13_-_31166544 0.81 ENSDART00000146250
ENSDART00000132129
ENSDART00000139591
mapk8a
mitogen-activated protein kinase 8a
chr9_-_52814204 0.80 ENSDART00000140771
ENSDART00000007401
MAP3K13
si:ch211-45c16.2
chr14_-_46238186 0.73 ENSDART00000173245
si:ch211-113d11.6
si:ch211-113d11.6
chr11_+_13224281 0.69 ENSDART00000102557
ENSDART00000178706
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr2_-_58142854 0.61 ENSDART00000169909
CABZ01110881.1

chr5_-_69312533 0.58 ENSDART00000082614
ENSDART00000183098
smtnb
smoothelin b
chr23_+_44665230 0.56 ENSDART00000144958
camta2
calmodulin binding transcription activator 2
chr7_+_73780936 0.55 ENSDART00000092691
pea15
proliferation and apoptosis adaptor protein 15
chr20_+_54037138 0.53 ENSDART00000143172
wdr20b
WD repeat domain 20b
chr5_-_38155005 0.51 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr10_+_2876020 0.47 ENSDART00000136618
ENSDART00000133128
ENSDART00000140803
ENSDART00000141505
ccar2
cell cycle and apoptosis regulator 2
chr25_+_33063762 0.43 ENSDART00000189974
tln2b
talin 2b
chr18_+_36782930 0.43 ENSDART00000004129
si:ch211-160d20.3
si:ch211-160d20.3
chr1_+_9994811 0.42 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr2_+_45548890 0.42 ENSDART00000113994
fndc7a
fibronectin type III domain containing 7a
chr20_+_2460864 0.41 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr23_-_29505645 0.40 ENSDART00000146458
kif1b
kinesin family member 1B
chr12_+_19976400 0.39 ENSDART00000153177
mkl2a
MKL/myocardin-like 2a
chr7_-_52709759 0.38 ENSDART00000136745
ENSDART00000131282
ENSDART00000073766
ENSDART00000161387
ENSDART00000174117
ENSDART00000174355
tcf12
transcription factor 12
chr4_-_20043484 0.37 ENSDART00000167780
zgc:193726
zgc:193726
chr15_+_42626957 0.36 ENSDART00000154754
grik1b
glutamate receptor, ionotropic, kainate 1b
chr20_+_1278184 0.34 ENSDART00000039616
lrp11
low density lipoprotein receptor-related protein 11
chr17_-_50022827 0.34 ENSDART00000161008
filip1a
filamin A interacting protein 1a
chr16_+_14033121 0.33 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr16_+_1254390 0.32 ENSDART00000092627
ADAMTSL4
ADAMTS like 4
chr7_+_38510197 0.32 ENSDART00000173468
ENSDART00000100479
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr3_-_36932515 0.32 ENSDART00000111981
ENSDART00000188470
cntnap1
contactin associated protein 1
chr24_+_30392834 0.30 ENSDART00000162555
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr21_-_1625976 0.29 ENSDART00000066621
vmo1b
vitelline membrane outer layer 1 homolog b
chr3_-_4303262 0.29 ENSDART00000112819
si:dkey-73p2.2
si:dkey-73p2.2
chr10_-_29101715 0.29 ENSDART00000149674
ENSDART00000171194
ENSDART00000192019
si:ch211-103f14.3
si:ch211-103f14.3
chr23_-_24047054 0.28 ENSDART00000184308
ENSDART00000185902
CR925720.1

chr19_-_45650994 0.27 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr16_+_41570653 0.27 ENSDART00000102665
aste1a
asteroid homolog 1a
chr17_-_51224800 0.27 ENSDART00000150089
psen1
presenilin 1
chr2_+_42871831 0.24 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr22_-_19102256 0.24 ENSDART00000171866
ENSDART00000166295
polrmt
polymerase (RNA) mitochondrial (DNA directed)
chr6_+_13933464 0.22 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr23_-_27101600 0.22 ENSDART00000139231
stat6
signal transducer and activator of transcription 6, interleukin-4 induced
chr4_+_61840440 0.22 ENSDART00000169427
si:dkey-16p6.1
si:dkey-16p6.1
chr2_+_42072231 0.22 ENSDART00000084517
vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr12_-_25097520 0.22 ENSDART00000158036
cript
cysteine-rich PDZ-binding protein
chr18_+_3052408 0.21 ENSDART00000181563
kctd14
potassium channel tetramerization domain containing 14
chr9_-_14992730 0.21 ENSDART00000137117
pard3bb
par-3 family cell polarity regulator beta b
chr4_+_54618332 0.20 ENSDART00000171824
si:ch211-227e10.2
si:ch211-227e10.2
chr12_+_13652361 0.20 ENSDART00000182757
ENSDART00000152689
oplah
5-oxoprolinase, ATP-hydrolysing
chr1_+_7956030 0.20 ENSDART00000159655
CR855320.1

chr24_-_6644734 0.20 ENSDART00000167391
arhgap21a
Rho GTPase activating protein 21a
chr5_+_64277604 0.20 ENSDART00000111282
qsox2
quiescin Q6 sulfhydryl oxidase 2
chr23_+_45734011 0.20 ENSDART00000062415
CABZ01088025.1

chr12_-_46252062 0.19 ENSDART00000153223
si:ch211-226h7.5
si:ch211-226h7.5
chr24_-_6546479 0.19 ENSDART00000160538
arhgap21a
Rho GTPase activating protein 21a
chr19_-_32042105 0.19 ENSDART00000088358
znf704
zinc finger protein 704
chr5_-_29112956 0.18 ENSDART00000132726
whrnb
whirlin b
chr10_-_35410518 0.18 ENSDART00000048430
gabrr3a
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr13_-_4704353 0.17 ENSDART00000171900
oit3
oncoprotein induced transcript 3
chr8_+_36500061 0.17 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr3_-_10634438 0.17 ENSDART00000093037
ENSDART00000130761
ENSDART00000156617
map2k4a
mitogen-activated protein kinase kinase 4a
chr24_+_31277360 0.17 ENSDART00000165993
f3a
coagulation factor IIIa
chr22_+_21972824 0.17 ENSDART00000183708
ENSDART00000133739
gna15.3
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3
chr21_+_39365920 0.16 ENSDART00000140940
cluhb
clustered mitochondria (cluA/CLU1) homolog b
chr7_+_57109214 0.16 ENSDART00000135068
ENSDART00000098412
enosf1
enolase superfamily member 1
chr13_+_40034176 0.16 ENSDART00000189797
golga7bb
golgin A7 family, member Bb
chr18_+_31410652 0.15 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr8_+_8973425 0.15 ENSDART00000066107
bcap31
B cell receptor associated protein 31
chr1_+_37195465 0.15 ENSDART00000043855
ENSDART00000192580
ENSDART00000181666
dclk2a
doublecortin-like kinase 2a
chr17_+_10578823 0.15 ENSDART00000134610
mgaa
MGA, MAX dimerization protein a
chr14_+_8940326 0.14 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr16_-_25606235 0.14 ENSDART00000192741
zgc:110410
zgc:110410
chr12_+_20618336 0.14 ENSDART00000084007
si:dkey-220f10.4
si:dkey-220f10.4
chr1_+_37195919 0.13 ENSDART00000159684
ENSDART00000172742
ENSDART00000158395
dclk2a
doublecortin-like kinase 2a
chr3_+_28953274 0.12 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr23_-_15878879 0.12 ENSDART00000010119
eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr4_-_815871 0.12 ENSDART00000067455
dpysl5b
dihydropyrimidinase-like 5b
chr10_-_28193642 0.11 ENSDART00000019050
rps6kb1a
ribosomal protein S6 kinase b, polypeptide 1a
chr8_-_18532957 0.11 ENSDART00000192783
ENSDART00000190530
nexn
nexilin (F actin binding protein)
chr21_+_3928947 0.11 ENSDART00000149777
setx
senataxin
chr8_+_36500308 0.11 ENSDART00000098701
slc7a4
solute carrier family 7, member 4
chr2_+_42072689 0.10 ENSDART00000134203
vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr22_-_10586191 0.10 ENSDART00000148418
si:dkey-42i9.16
si:dkey-42i9.16
chr24_-_6078222 0.10 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr12_+_20618522 0.10 ENSDART00000091452
si:dkey-220f10.4
si:dkey-220f10.4
chr20_+_12702923 0.10 ENSDART00000163499
zgc:153383
zgc:153383
chr12_-_46315898 0.10 ENSDART00000153138
si:ch211-226h7.3
si:ch211-226h7.3
chr6_+_58406014 0.10 ENSDART00000044241
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr21_-_2322102 0.09 ENSDART00000162867
zgc:66483
zgc:66483
chr7_+_17716601 0.09 ENSDART00000173792
ENSDART00000080825
rtn3
reticulon 3
chr16_+_13818500 0.09 ENSDART00000135245
flcn
folliculin
chr15_-_47812268 0.08 ENSDART00000190231
tomt
transmembrane O-methyltransferase
chr9_+_14023386 0.08 ENSDART00000140199
ENSDART00000124267
si:ch211-67e16.4
si:ch211-67e16.4
chr9_+_29985010 0.08 ENSDART00000020743
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr11_-_43002262 0.08 ENSDART00000172477
ENSDART00000181513
CABZ01069998.1

chr8_+_47342586 0.08 ENSDART00000007624
plch2a
phospholipase C, eta 2a
chr13_+_22421151 0.07 ENSDART00000122687
opn4a
opsin 4a (melanopsin)
chr14_-_21238046 0.07 ENSDART00000129743
si:ch211-175m2.5
si:ch211-175m2.5
chr13_+_30215765 0.07 ENSDART00000041026
ENSDART00000133049
qrfpra
pyroglutamylated RFamide peptide receptor a
chr25_+_35133404 0.07 ENSDART00000188505
hist1h2a2
histone cluster 1 H2A family member 2
chr10_-_18463934 0.06 ENSDART00000133116
ENSDART00000113422
si:dkey-28o19.1
si:dkey-28o19.1
chr9_+_21281652 0.06 ENSDART00000113352
lats2
large tumor suppressor kinase 2
chr19_-_24218942 0.06 ENSDART00000189198
BX547993.2

chr3_+_23047241 0.06 ENSDART00000103858
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr13_+_35635672 0.06 ENSDART00000148481
thbs2a
thrombospondin 2a
chr1_+_58066109 0.05 ENSDART00000115190
si:ch211-114l13.4
si:ch211-114l13.4
chr18_+_27439680 0.05 ENSDART00000014726
tp53i11b
tumor protein p53 inducible protein 11b
chr12_+_46841918 0.05 ENSDART00000157464
adkb
adenosine kinase b
chr4_+_53119675 0.05 ENSDART00000167470
si:dkey-8o9.2
si:dkey-8o9.2
chr4_-_32458327 0.05 ENSDART00000182527
si:dkey-16p6.1
si:dkey-16p6.1
chr11_+_42765963 0.05 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr20_-_49657134 0.04 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr13_+_8987957 0.04 ENSDART00000148144
hcar1-3
hydroxycarboxylic acid receptor 1-3
chr23_-_24542156 0.04 ENSDART00000132265
atp13a2
ATPase 13A2
chr4_-_76205022 0.04 ENSDART00000159687
ENSDART00000187593
si:ch211-106j21.5
si:ch211-106j21.5
chr1_+_58602506 0.03 ENSDART00000158425
si:ch73-221f6.1
si:ch73-221f6.1
chr19_-_11977783 0.03 ENSDART00000183337
si:ch1073-296d18.1
si:ch1073-296d18.1
chr21_-_38582061 0.03 ENSDART00000193891
ENSDART00000124349
pof1b
POF1B, actin binding protein
chr10_+_8481660 0.03 ENSDART00000109559
BX682234.1

chr16_-_42303856 0.02 ENSDART00000180030
ppox
protoporphyrinogen oxidase
chr23_+_6926183 0.02 ENSDART00000149882
si:ch211-117c9.1
si:ch211-117c9.1
chr25_+_9027831 0.02 ENSDART00000155855
im:7145024
im:7145024
chr4_-_71151245 0.02 ENSDART00000165415
si:dkey-193i10.4
si:dkey-193i10.4
chr20_+_51466046 0.02 ENSDART00000178065
tlr5b
toll-like receptor 5b
chr15_+_23356600 0.01 ENSDART00000113279
rnf26
ring finger protein 26
chr14_+_20351 0.01 ENSDART00000051893
stx18
syntaxin 18
chr4_+_49196098 0.01 ENSDART00000150678
si:dkey-40n15.1
si:dkey-40n15.1
chr1_-_633356 0.01 ENSDART00000171019
appa
amyloid beta (A4) precursor protein a
chr4_+_20177526 0.01 ENSDART00000017947
ENSDART00000135451
ccdc146
coiled-coil domain containing 146
chr11_-_33960318 0.01 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr16_+_53387085 0.01 ENSDART00000154223
ENSDART00000101404
kif13a
kinesin family member 13A
chr9_+_29603649 0.00 ENSDART00000140477
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr11_+_42726712 0.00 ENSDART00000028955
tdrd3
tudor domain containing 3
chr22_+_19478140 0.00 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
si:dkey-78l4.8
chr25_+_32157326 0.00 ENSDART00000112588
tjp1b
tight junction protein 1b
chr5_-_69523816 0.00 ENSDART00000112692
si:ch211-157p22.10
si:ch211-157p22.10

Network of associatons between targets according to the STRING database.

First level regulatory network of arid5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.7 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 0.9 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.4 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 0.3 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.3 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 0.3 GO:0019860 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.1 0.3 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0032288 myelin assembly(GO:0032288)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 1.0 GO:0007254 JNK cascade(GO:0007254)
0.0 0.6 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.1 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 1.0 GO:0043209 myelin sheath(GO:0043209)
0.1 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 0.9 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.7 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis