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PRJEB1986: zebrafish developmental stages transcriptome

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Results for arid5a+arid6

Z-value: 0.64

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Transcription factors associated with arid5a+arid6

Gene Symbol Gene ID Gene Info
ENSDARG00000069988 AT-rich interaction domain 6
ENSDARG00000077120 AT rich interactive domain 5A (MRF1-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid6dr11_v1_chr21_+_11244068_112440680.126.2e-01Click!
arid5adr11_v1_chr8_+_52377516_523775160.077.7e-01Click!

Activity profile of arid5a+arid6 motif

Sorted Z-values of arid5a+arid6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_53344726 0.89 ENSDART00000184395
ENSDART00000170212

chr4_+_15944245 0.77 ENSDART00000134594
si:dkey-117n7.3
chr23_+_5631381 0.77 ENSDART00000149143
plakophilin 1a
chr2_-_44280061 0.73 ENSDART00000136818
myelin protein zero
chr4_-_8043839 0.72 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr10_+_15967341 0.67 ENSDART00000115130
ENSDART00000189687
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_1948236 0.67 ENSDART00000163344
zinc and ring finger 2a
chr3_-_38915998 0.65 ENSDART00000141886
si:dkey-106c17.2
chr20_-_9755546 0.61 ENSDART00000152498
ENSDART00000152239
si:dkey-63j12.4
chr23_+_383782 0.60 ENSDART00000055148
zgc:101663
chr21_+_36623162 0.54 ENSDART00000027459
G protein-coupled receptor kinase 6
chr6_+_45932276 0.54 ENSDART00000103491
retinol binding protein 7b, cellular
chr24_-_11446156 0.54 ENSDART00000143921
ENSDART00000066778
acyl-CoA dehydrogenase family, member 11
chr21_-_2261720 0.52 ENSDART00000170161
si:ch73-299h12.2
chr22_+_15343953 0.51 ENSDART00000045682
ribosomal RNA processing 36
chr22_-_606067 0.50 ENSDART00000136722
cyclin-dependent kinase inhibitor 1A
chr21_+_20903244 0.50 ENSDART00000186193
complement component 7b
chr6_-_8466717 0.49 ENSDART00000151577
ENSDART00000151800
ENSDART00000151227
si:dkey-217d24.6
chr10_+_38526496 0.49 ENSDART00000144329
alkaline ceramidase 3
chr10_+_44699734 0.48 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scavenger receptor class B, member 1
chr2_+_21048661 0.47 ENSDART00000156876
ras responsive element binding protein 1b
chr4_+_12031958 0.47 ENSDART00000044154
troponin T2c, cardiac
chr5_+_13427826 0.46 ENSDART00000083359
SEC14-like lipid binding 8
chr19_+_21820144 0.46 ENSDART00000181996

chr17_-_24564674 0.45 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr3_+_3641429 0.43 ENSDART00000092393
phospholipase B domain containing 1
chr1_+_29068654 0.43 ENSDART00000053932
cystathionine-beta-synthase a
chr13_-_12021566 0.42 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr16_+_26777473 0.42 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr19_-_1947403 0.41 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr7_+_20467549 0.40 ENSDART00000173724
si:dkey-33c9.8
chr14_-_34700633 0.40 ENSDART00000150358
actin binding LIM protein family, member 3
chr20_+_1960092 0.39 ENSDART00000191892

chr1_-_50838160 0.38 ENSDART00000163939
ENSDART00000165111
zgc:154142
chr12_+_2665081 0.38 ENSDART00000147532
retinol binding protein 3
chr7_+_36484598 0.37 ENSDART00000173595
chromodomain helicase DNA binding protein 9
chr5_-_66429357 0.36 ENSDART00000160189
huntingtin interacting protein 1 related b
chr7_-_30925798 0.36 ENSDART00000149303
sorbitol dehydrogenase
chr2_-_20715094 0.36 ENSDART00000155439
dual specificity phosphatase 12
chr10_-_43655449 0.36 ENSDART00000099134
myocyte enhancer factor 2ca
chr10_+_45089820 0.36 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr24_-_36238054 0.36 ENSDART00000155725
transmembrane protein 241
chr8_+_29636431 0.36 ENSDART00000133047
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr18_+_15876385 0.36 ENSDART00000142527
early endosome antigen 1
chr16_-_4836218 0.35 ENSDART00000054077
trophoblast glycoprotein b
chr20_+_46925581 0.35 ENSDART00000192531
si:ch73-21k16.5
chr1_+_32054159 0.34 ENSDART00000181442
steroid sulfatase (microsomal), isozyme S
chr4_+_42604252 0.34 ENSDART00000184850

chr1_+_21731382 0.34 ENSDART00000054395
paired box 5
chr13_-_28689717 0.34 ENSDART00000101582
polycomb group ring finger 6
chr9_+_52492639 0.34 ENSDART00000078939
membrane-associated ring finger (C3HC4) 4
chr11_+_25504215 0.34 ENSDART00000154213
transcription factor binding to IGHM enhancer 3b
chr5_-_42059869 0.34 ENSDART00000193984
centromere protein V
chr23_+_45512825 0.33 ENSDART00000064846
PRELI domain containing 1b
chr22_+_36656680 0.33 ENSDART00000134031
ENSDART00000056169
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr19_-_48336535 0.33 ENSDART00000162752
si:ch73-359m17.6
chr2_-_57110477 0.33 ENSDART00000181132
solute carrier family 25, member 42
chr9_+_37329036 0.33 ENSDART00000131756
solute carrier family 15 (oligopeptide transporter), member 2
chr7_+_39399747 0.32 ENSDART00000147037
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr16_-_45917683 0.32 ENSDART00000184289
antifreeze protein type IV
chr15_-_35410860 0.32 ENSDART00000191267
MDS1 and EVI1 complex locus
chr10_+_9601587 0.32 ENSDART00000147997
ring finger and CCCH-type domains 2
chr4_+_30776883 0.32 ENSDART00000169519
si:dkey-11d20.1
chr23_+_19655301 0.32 ENSDART00000104441
ENSDART00000135269
abhydrolase domain containing 6b
chr14_+_909769 0.30 ENSDART00000021346
ENSDART00000172777
ADP-ribosylation factor-like 3, like 2
chr17_-_15188440 0.29 ENSDART00000151885
WD repeat and HMG-box DNA binding protein 1
chr7_+_15659280 0.29 ENSDART00000173414
myocyte enhancer factor 2ab
chr24_-_14712427 0.29 ENSDART00000176316
junctophilin 1a
chr5_-_28767573 0.29 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr17_+_8324345 0.29 ENSDART00000172443
CDC42 binding protein kinase alpha (DMPK-like) a
chr24_+_26328787 0.29 ENSDART00000003884
myoneurin
chr21_-_4695583 0.29 ENSDART00000031425
zgc:55582
chr23_-_35483163 0.29 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr22_-_36519590 0.28 ENSDART00000129318

chr14_-_38889311 0.28 ENSDART00000186978
zgc:101583
chr15_-_33933790 0.28 ENSDART00000165162
ENSDART00000182258
ENSDART00000183240
myelin associated glycoprotein
chr4_+_42450386 0.28 ENSDART00000168211
si:dkey-11d20.1
chr9_-_18911608 0.28 ENSDART00000138785
si:dkey-239h2.3
chr4_+_288633 0.28 ENSDART00000183304

chr5_+_28797771 0.28 ENSDART00000188845
ENSDART00000149066
si:ch211-186e20.7
chr25_+_4760489 0.28 ENSDART00000167399

chr6_+_24420523 0.28 ENSDART00000185461
transforming growth factor, beta receptor III
chr23_-_33709964 0.27 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr6_+_7322587 0.27 ENSDART00000065500
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr11_-_41853874 0.27 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr23_+_43950674 0.27 ENSDART00000167813
corin, serine peptidase
chr6_-_32411703 0.27 ENSDART00000151002
ENSDART00000078908
ubiquitin specific peptidase 1
chr5_-_67878064 0.26 ENSDART00000111203
transgelin 3a
chr9_+_38158570 0.26 ENSDART00000059549
ENSDART00000133060
nucleolar protein interacting with the FHA domain of MKI67
chr7_+_20876303 0.26 ENSDART00000173495
ENSDART00000164172
GRB10 interacting GYF protein 1a
chr24_-_28419444 0.26 ENSDART00000105749
negative regulator of reactive oxygen species
chr1_+_53714734 0.26 ENSDART00000114689
pseudouridylate synthase 10
chr13_-_9895564 0.26 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
chr12_+_16132612 0.26 ENSDART00000152550
low density lipoprotein receptor-related protein 2b
chr11_+_13041341 0.26 ENSDART00000166126
ENSDART00000162074
ENSDART00000170889
basic transcription factor 3-like 4
chr11_-_45140227 0.26 ENSDART00000184062
calcium activated nucleotidase 1b
chr1_-_25438737 0.26 ENSDART00000134470
FH2 domain containing 1
chr4_-_57001458 0.25 ENSDART00000158660
si:ch211-161m3.1
chr5_+_37837245 0.25 ENSDART00000171617
ependymin
chr14_-_2004291 0.25 ENSDART00000114039
protocadherin 2 gamma 5
chr1_-_25438934 0.25 ENSDART00000111686
FH2 domain containing 1
chr18_+_3634652 0.25 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr1_-_51219965 0.25 ENSDART00000146612
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr4_-_9637398 0.24 ENSDART00000150253
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr11_-_3535537 0.24 ENSDART00000165329
ENSDART00000009788
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr2_+_1714640 0.24 ENSDART00000086761
ENSDART00000111613
adhesion G protein-coupled receptor L2b, tandem duplicate 1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr10_+_15024772 0.24 ENSDART00000135667
si:dkey-88l16.5
chr9_-_2572790 0.24 ENSDART00000135076
ENSDART00000016710
secernin 3
chr15_+_25156382 0.24 ENSDART00000171092
info solute carrier family 35, member F2, like
chr25_-_8138122 0.24 ENSDART00000104659
secretion regulating guanine nucleotide exchange factor
chr24_-_3783258 0.23 ENSDART00000139596
adenosine deaminase, RNA-specific, B2 (non-functional)
chr8_+_53423408 0.23 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr9_-_41040492 0.23 ENSDART00000163164
adenosine deaminase, tRNA-specific 3
chr16_-_28091597 0.23 ENSDART00000166595

chr6_+_58698475 0.23 ENSDART00000056138
immunoglobulin superfamily, member 8
chr9_+_34232503 0.23 ENSDART00000132836
neurexophilin and PC-esterase domain family, member 3
chr17_+_47116500 0.23 ENSDART00000186627
si:dkeyp-47f9.4
chr20_-_26537171 0.23 ENSDART00000061926
syntaxin 11b, tandem duplicate 2
chr17_-_5424175 0.23 ENSDART00000171063
ENSDART00000188102
SPT3 homolog, SAGA and STAGA complex component
chr25_+_34984333 0.23 ENSDART00000154760
coiled-coil domain containing 136b
chr15_+_44201056 0.23 ENSDART00000162433
ENSDART00000148336

chr25_-_7670616 0.23 ENSDART00000131583
ENSDART00000142794
Bet1 golgi vesicular membrane trafficking protein-like
chr24_-_3783497 0.22 ENSDART00000158354
adenosine deaminase, RNA-specific, B2 (non-functional)
chr11_+_1628538 0.22 ENSDART00000154967
low density lipoprotein receptor-related protein 1Aa
chr19_-_47323267 0.22 ENSDART00000190077

chr9_+_13229585 0.22 ENSDART00000154879
ENSDART00000141705
calcium responsive transcription factor
chr12_+_16168342 0.22 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr21_+_43702016 0.22 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr22_-_2959005 0.22 ENSDART00000040701
inhibitor of growth family, member 5a
chr8_+_7975745 0.22 ENSDART00000137920
si:ch211-169p10.1
chr14_+_22114918 0.22 ENSDART00000166610
thioredoxin-related transmembrane protein 2a
chr13_+_40770628 0.22 ENSDART00000085846
NK1 transcription factor related 2-like,a
chr15_+_31276869 0.21 ENSDART00000156355
si:ch211-244e12.7
chr11_+_3585934 0.21 ENSDART00000055694
cytidine deaminase b
chr16_-_41488023 0.21 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr6_-_11091449 0.21 ENSDART00000127209
PTTG1 interacting protein a
chr18_-_2433011 0.21 ENSDART00000181922
ENSDART00000193276

chr9_+_24708653 0.21 ENSDART00000065136

chr10_+_33573838 0.21 ENSDART00000051197
ENSDART00000130093
c10h21orf59 homolog (H. sapiens)
chr7_-_30779575 0.21 ENSDART00000004782
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr23_-_16843649 0.21 ENSDART00000129971
si:dkey-63j12.4
chr7_+_20917966 0.21 ENSDART00000129161
WD repeat containing, antisense to TP53
chr10_+_16092671 0.21 ENSDART00000182761
ENSDART00000154835
multiple EGF-like-domains 10
chr7_-_30926030 0.20 ENSDART00000075421
sorbitol dehydrogenase
chr21_+_41468210 0.20 ENSDART00000192287
biorientation of chromosomes in cell division 1
chr21_-_5077715 0.20 ENSDART00000081954
HAUS augmin-like complex, subunit 1
chr2_+_42871831 0.20 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr15_-_26844591 0.20 ENSDART00000077582
PITPNM family member 3
chr7_-_5191797 0.20 ENSDART00000172955
si:ch73-223f5.1
chr8_+_41229233 0.20 ENSDART00000131135
zgc:152830
chr16_+_5184402 0.20 ENSDART00000156685
SOGA family member 3a
chr25_-_22889519 0.20 ENSDART00000128250
MOB kinase activator 2a
chr15_-_2519640 0.20 ENSDART00000047013
signal recognition particle receptor, B subunit
chr5_+_45990046 0.20 ENSDART00000084024
synaptic vesicle glycoprotein 2C
chr6_+_3680651 0.20 ENSDART00000013588
kelch-like family member 41b
chr18_+_40471826 0.20 ENSDART00000098806
UDP glucuronosyltransferase 5 family, polypeptide C3
chr25_+_31323978 0.19 ENSDART00000067030
lymphocyte-specific protein 1
chr2_-_32825917 0.19 ENSDART00000180409
pre-mRNA processing factor 4Ba
chr6_-_16406210 0.19 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr5_-_33886495 0.19 ENSDART00000159058
DAB2 interacting protein b
chr21_+_21692307 0.19 ENSDART00000139330
odorant receptor, family E, subfamily 125, member 3
chr15_-_21165237 0.19 ENSDART00000157069
si:ch211-212c13.8
chr13_-_18695289 0.19 ENSDART00000176809
sideroflexin 3
chr6_-_55399214 0.19 ENSDART00000168367
cathepsin A
chr25_-_29074064 0.18 ENSDART00000165603
AT rich interactive domain 3B (BRIGHT-like)
chr11_+_36408636 0.18 ENSDART00000182098
cytochrome b561 family, member D1
chr25_-_3132060 0.18 ENSDART00000014363
eosinophil peroxidase
chr15_-_1765098 0.18 ENSDART00000149980
ENSDART00000093074
BUD23, rRNA methyltransferase and ribosome maturation factor
chr21_-_3825135 0.18 ENSDART00000133792
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr20_+_54037138 0.18 ENSDART00000143172
WD repeat domain 20b
chr3_-_61362398 0.18 ENSDART00000156177
si:dkey-111k8.3
chr9_+_33207574 0.18 ENSDART00000055897
ENSDART00000166030
si:ch211-125e6.11
chr17_+_24632440 0.18 ENSDART00000157092
mitogen-activated protein kinase kinase kinase kinase 3b
chr9_+_32301017 0.18 ENSDART00000127916
ENSDART00000183298
ENSDART00000143103
heat shock 10 protein 1
chr17_-_37184655 0.18 ENSDART00000180447
additional sex combs like transcriptional regulator 2
chr18_-_24988645 0.18 ENSDART00000136434
ENSDART00000085735
chromodomain helicase DNA binding protein 2
chr14_-_35414559 0.18 ENSDART00000145033
ribonuclease H2, subunit C
chr23_-_35790235 0.18 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
major facilitator superfamily domain containing 5
chr10_-_41940302 0.18 ENSDART00000033121
MORN repeat containing 3
chr22_-_11623063 0.18 ENSDART00000145653
glucagon a
chr24_+_13925066 0.18 ENSDART00000134221
ENSDART00000012253
ENSDART00000081595
ENSDART00000136443
EYA transcriptional coactivator and phosphatase 1
chr10_-_25204034 0.17 ENSDART00000161100
si:ch211-214k5.6
chr2_+_40294313 0.17 ENSDART00000037292
eph receptor A4b
chr6_-_57635577 0.17 ENSDART00000168708
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr16_-_8927425 0.17 ENSDART00000000382
trio Rho guanine nucleotide exchange factor b
chr10_+_40160502 0.17 ENSDART00000171879
GRAM domain containing 1Ba
chr13_-_40316367 0.17 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr10_-_11012000 0.17 ENSDART00000132995
adenylate kinase 3
chr22_+_19247255 0.17 ENSDART00000144053
si:dkey-21e2.10
chr14_-_22015232 0.17 ENSDART00000137795
structure specific recognition protein 1a
chr16_-_21620947 0.17 ENSDART00000115011
ENSDART00000183125
ENSDART00000188856
ENSDART00000189460
discoidin domain receptor tyrosine kinase 1
chr8_-_4327473 0.17 ENSDART00000134378
cut-like homeobox 2b
chr21_-_21530868 0.17 ENSDART00000174231
odorant receptor, family H, subfamily 133, member 9
chr23_-_5683147 0.17 ENSDART00000102766
ENSDART00000067351
troponin T type 2a (cardiac)
chr4_+_74928675 0.17 ENSDART00000192755
nucleoporin 50
chr7_+_30178453 0.17 ENSDART00000174420
si:ch211-107o10.3
chr3_-_46410387 0.17 ENSDART00000156822
cell death-inducing p53 target 1
chr24_-_25166416 0.17 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr4_+_17671164 0.17 ENSDART00000040445
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr18_+_20468157 0.17 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
damage-specific DNA binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of arid5a+arid6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 0.5 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.4 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 0.1 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.3 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.1 0.4 GO:0070814 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.2 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.1 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.6 GO:0019405 alditol catabolic process(GO:0019405)
0.1 0.5 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.2 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.1 0.3 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.3 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.5 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.3 GO:0071632 optomotor response(GO:0071632)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.1 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0045453 bone resorption(GO:0045453)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.4 GO:0098754 detoxification(GO:0098754)
0.0 0.2 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272) nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.2 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.0 0.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0002931 response to ischemia(GO:0002931)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0003218 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:1990077 primosome complex(GO:1990077)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0030681 fibrillar center(GO:0001650) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.6 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.1 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:1900750 oligopeptide binding(GO:1900750)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport