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PRJEB1986: zebrafish developmental stages transcriptome

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Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 1.24

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Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Gene Symbol Gene ID Gene Info
ENSDARG00000107408 transcription factor 4
ENSDARG00000045131 inhibitor of DNA binding 4
ENSDARG00000017078 mesoderm posterior aa
ENSDARG00000030347 mesoderm posterior ba
ENSDARG00000068761 mesoderm posterior ab
ENSDARG00000097947 mesoderm posterior bb
ENSDARG00000110553 mesoderm posterior ba
ENSDARG00000114890 mesoderm posterior aa

Activity-expression correlation:

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_39446247 4.85 ENSDART00000033610
ENSDART00000099015
troponin T type 3b (skeletal, fast)
chr16_+_12022543 4.44 ENSDART00000012673
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr6_+_42918933 4.41 ENSDART00000064896
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr22_+_7439476 4.19 ENSDART00000021594
ENSDART00000063389
zgc:92041
chr19_+_233143 3.54 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr16_-_36834505 3.48 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr2_-_22688651 3.19 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr22_+_7439186 3.17 ENSDART00000190667
zgc:92041
chr15_-_43164591 3.13 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr16_-_16152199 2.96 ENSDART00000012718
fatty acid binding protein 11b
chr1_+_8662530 2.84 ENSDART00000054989
fascin actin-bundling protein 1b
chr13_+_50375800 2.84 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr2_-_26001173 2.75 ENSDART00000010615
claudin 11a
chr11_-_101758 2.74 ENSDART00000173015
engulfment and cell motility 2
chr14_+_15155684 2.63 ENSDART00000167966
zgc:158852
chr23_-_26535875 2.60 ENSDART00000135988
si:dkey-205h13.2
chr16_+_52512025 2.54 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr6_+_29305190 2.52 ENSDART00000078647
si:ch211-201h21.5
chr5_+_37837245 2.48 ENSDART00000171617
ependymin
chr21_+_11468642 2.38 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr15_-_576135 2.32 ENSDART00000124170
cerebellin 20
chr7_+_22616212 2.25 ENSDART00000052844
claudin 7a
chr17_-_52595932 2.24 ENSDART00000127225
si:ch211-173a9.7
chr12_-_10220036 2.24 ENSDART00000134619
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr4_-_9549693 2.21 ENSDART00000160242

chr2_+_5621529 2.18 ENSDART00000144187
fibroblast growth factor 12a
chr8_+_50727220 2.15 ENSDART00000127062
early growth response 3
chr16_-_17207754 2.15 ENSDART00000063804
wu:fj39g12
chr23_+_17387325 2.15 ENSDART00000083947
PTK6 protein tyrosine kinase 6b
chr14_+_6159356 2.13 ENSDART00000157730
Bernardinelli-Seip congenital lipodystrophy 2, like
chr15_-_12011390 2.12 ENSDART00000187403
si:dkey-202l22.6
chr12_-_47601845 2.11 ENSDART00000169548
ENSDART00000182889
regulator of G protein signaling 7b
chr12_-_17810543 2.08 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr23_-_17657348 2.04 ENSDART00000054736
basic helix-loop-helix family, member e23
chr6_+_42338309 2.03 ENSDART00000015277
glutathione peroxidase 1b
chr3_+_32526799 2.00 ENSDART00000185755
si:ch73-367p23.2
chr23_+_6795531 1.98 ENSDART00000092131
si:ch211-117c9.5
chr20_+_41549200 1.83 ENSDART00000135715
family with sequence similarity 184, member A
chr23_-_26536055 1.82 ENSDART00000182719
si:dkey-205h13.2
chr7_+_61184551 1.82 ENSDART00000190788
zgc:194930
chr2_+_51796441 1.79 ENSDART00000165151
crystallin, gamma N1
chr24_+_35564668 1.77 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr18_+_46773198 1.76 ENSDART00000174647

chr5_-_11573490 1.76 ENSDART00000109577

chr23_+_6077503 1.75 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr9_-_22158784 1.75 ENSDART00000167850
crystallin, gamma M2d14
chr3_+_42923275 1.74 ENSDART00000168228
transmembrane protein 184a
chr11_+_43401201 1.74 ENSDART00000190128
vasoactive intestinal peptide b
chr7_+_22767678 1.73 ENSDART00000137203
plac8 onzin related protein 6
chr23_-_3674443 1.72 ENSDART00000134830
ENSDART00000057422
protein kinase C and casein kinase substrate in neurons 1a
chr9_-_43375205 1.70 ENSDART00000138436
zinc finger protein 385B
chr23_+_39854566 1.67 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr23_-_29556844 1.67 ENSDART00000138021
retinol binding protein 7a, cellular
chr7_-_38638809 1.67 ENSDART00000144341
six-cysteine containing astacin protease 4
chr5_-_23855447 1.67 ENSDART00000051541
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
chr17_-_38887424 1.62 ENSDART00000141177
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr3_+_32526263 1.62 ENSDART00000150897
si:ch73-367p23.2
chr5_+_36932718 1.61 ENSDART00000037879
cone-rod homeobox
chr19_-_7450796 1.60 ENSDART00000104750
MLLT11, transcription factor 7 cofactor
chr1_-_50838160 1.59 ENSDART00000163939
ENSDART00000165111
zgc:154142
chr23_+_2542158 1.59 ENSDART00000182197

chr25_-_207214 1.59 ENSDART00000193448

chr22_-_10110959 1.58 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr21_+_11468934 1.58 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr25_-_12203952 1.58 ENSDART00000158204
ENSDART00000091727
neurotrophic tyrosine kinase, receptor, type 3a
chr20_+_22681066 1.57 ENSDART00000143286
ligand of numb-protein X 1
chr8_+_24861264 1.57 ENSDART00000099607
solute carrier family 6 (neutral amino acid transporter), member 17
chr3_+_32553714 1.56 ENSDART00000165638
paired box 10
chr20_-_9436521 1.55 ENSDART00000133000
zgc:101840
chr21_-_41873584 1.55 ENSDART00000188089
endonuclease, polyU-specific 2
chr1_+_12009673 1.55 ENSDART00000080100
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr17_+_20204122 1.54 ENSDART00000078672
gonadotropin-releasing hormone 3
chr20_-_8419057 1.53 ENSDART00000145841
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr7_+_31879986 1.53 ENSDART00000138491
myosin binding protein C, cardiac
chr17_+_1063988 1.53 ENSDART00000160400
GTP cyclohydrolase I feedback regulator
chr8_+_16025554 1.52 ENSDART00000110171
ELAV like neuron-specific RNA binding protein 4
chr18_+_23249519 1.52 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
myocyte enhancer factor 2aa
chr6_-_35472923 1.51 ENSDART00000185907
regulator of G protein signaling 8
chr14_+_35748385 1.51 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
glutamate receptor, ionotropic, AMPA 2b
chr4_+_26496489 1.50 ENSDART00000160652
IQ motif and Sec7 domain 3a
chr1_+_30422143 1.49 ENSDART00000033024
transmembrane protein 41ab
chr7_-_73725701 1.47 ENSDART00000158525
calsequestrin 1b
chr4_-_14328997 1.47 ENSDART00000091151
neural EGFL like 2b
chr3_-_61218272 1.46 ENSDART00000133091
ENSDART00000055068
parvalbumin 5
chr14_+_35691889 1.46 ENSDART00000074685
glycine receptor, beta b
chr8_-_25980694 1.44 ENSDART00000135456
si:dkey-72l14.3
chr17_-_5610514 1.43 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr14_+_35748206 1.40 ENSDART00000177391
glutamate receptor, ionotropic, AMPA 2b
chr6_+_39184236 1.40 ENSDART00000156187
tachykinin 3b
chr21_-_7882905 1.39 ENSDART00000056561
S100 calcium binding protein Z
chr8_-_52413032 1.39 ENSDART00000183039

chr23_-_32156278 1.37 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr23_+_19594608 1.37 ENSDART00000134865
sarcolemma associated protein b
chr15_-_47929455 1.37 ENSDART00000064462
proteasome subunit alpha 6, like
chr25_-_169291 1.36 ENSDART00000128344
lipase, hepatic b
chr10_-_26744131 1.35 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr2_+_24868010 1.34 ENSDART00000078838
RAB3A, member RAS oncogene family, a
chr14_+_34547554 1.34 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr21_-_2287589 1.34 ENSDART00000161554
si:ch73-299h12.4
chr21_+_25187210 1.34 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
chr6_-_3514753 1.33 ENSDART00000151765
ubiquinol-cytochrome c reductase hinge protein
chr13_-_21688176 1.32 ENSDART00000063825
shadow of prion protein
chr6_-_609880 1.29 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr2_+_394166 1.29 ENSDART00000155733
myosin light chain kinase family, member 4a
chr19_+_8144556 1.29 ENSDART00000027274
ENSDART00000147218
ephrin-A3a
chr16_-_12984631 1.28 ENSDART00000184863
calcium channel, voltage-dependent, gamma subunit 7b
chr1_-_21909608 1.27 ENSDART00000139937
FERM and PDZ domain containing 1a
chr4_+_72797711 1.27 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr6_-_13783604 1.27 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr18_+_7345417 1.26 ENSDART00000041429
GLI pathogenesis-related 1b
chr1_-_45177373 1.25 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr9_+_310331 1.25 ENSDART00000172446
ENSDART00000187731
ENSDART00000193970
SH3 and cysteine rich domain 3
chr20_+_18551657 1.23 ENSDART00000147001
si:dkeyp-72h1.1
chr11_+_7264457 1.23 ENSDART00000154182
receptor accessory protein 6
chr19_-_2861444 1.23 ENSDART00000169053
C-type lectin domain family 3, member Bb
chr11_+_43401592 1.22 ENSDART00000112468
vasoactive intestinal peptide b
chr2_+_32796873 1.21 ENSDART00000077511
chemokine (C-C motif) receptor 9a
chr24_-_21588914 1.21 ENSDART00000152054
G protein-coupled receptor 12
chr6_-_16667886 1.21 ENSDART00000180854
ENSDART00000190116
unc-80 homolog (C. elegans)
chr9_+_7358749 1.20 ENSDART00000081660
Indian hedgehog homolog a
chr1_+_55140970 1.20 ENSDART00000039807
myoglobin
chr13_-_36911118 1.19 ENSDART00000048739
tripartite motif containing 9
chr3_-_61205711 1.19 ENSDART00000055062
parvalbumin 1
chr8_+_23142946 1.19 ENSDART00000152933
si:ch211-196c10.13
chr1_+_10118455 1.18 ENSDART00000152432
lecithin retinol acyltransferase b, tandem duplicate 2
chr21_-_37790727 1.18 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr23_-_39666519 1.17 ENSDART00000110868
ENSDART00000190961
von Willebrand factor A domain containing 1
chr7_+_31879649 1.17 ENSDART00000099789
myosin binding protein C, cardiac
chr7_-_38644560 1.17 ENSDART00000114934
six-cysteine containing astacin protease 3
chr12_+_6214041 1.16 ENSDART00000179759
protein kinase, cGMP-dependent, type Ib
chr6_-_345503 1.15 ENSDART00000168901
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr1_-_21483832 1.15 ENSDART00000102790
glycine receptor, beta a
chr2_-_9059955 1.14 ENSDART00000022768
adenylate kinase 5
chr10_+_45071603 1.14 ENSDART00000186505
ENSDART00000157573
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr23_+_6795709 1.13 ENSDART00000149136
si:ch211-117c9.5
chr5_-_37900350 1.13 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr9_-_44905867 1.12 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
chr1_-_1894722 1.12 ENSDART00000165669
si:ch211-132g1.3
chr17_+_15433518 1.12 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr16_-_13612650 1.09 ENSDART00000080372
D site albumin promoter binding protein b
chr23_-_7826849 1.09 ENSDART00000157612
myelin transcription factor 1b
chr16_+_34528409 1.09 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr14_-_33278084 1.08 ENSDART00000132850
START domain containing 14
chr4_-_4795205 1.08 ENSDART00000039313
zgc:162331
chr16_-_12723738 1.07 ENSDART00000080414
SH3 domain binding kinase family, member 3
chr16_-_26074529 1.06 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr12_+_30586599 1.06 ENSDART00000124920
ENSDART00000126984
nebulin-related anchoring protein
chr9_-_22182396 1.06 ENSDART00000101809
crystallin, gamma M2d6
chr17_-_15546862 1.06 ENSDART00000091021
collagen, type X, alpha 1a
chr25_+_28893615 1.06 ENSDART00000156994
ENSDART00000075151
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr2_-_49997055 1.06 ENSDART00000140294
si:ch211-106n13.3
chr5_-_24238733 1.05 ENSDART00000138170
phospholipid scramblase 3a
chr8_-_14050758 1.05 ENSDART00000133922
ATPase plasma membrane Ca2+ transporting 3a
chr25_-_4146947 1.04 ENSDART00000129268
fatty acid desaturase 2
chr5_-_69948099 1.04 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr5_-_26118855 1.03 ENSDART00000009028
elastase 3 like
chr11_+_6902946 1.03 ENSDART00000144006
CREB regulated transcription coactivator 1b
chr4_-_28158335 1.03 ENSDART00000134605
GRAM domain containing 4a
chr12_+_12112384 1.03 ENSDART00000152431
glutamate receptor, ionotropic, delta 1b
chr7_+_25858380 1.03 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr4_+_23223881 1.02 ENSDART00000133056
ENSDART00000089126
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr22_+_5106751 1.02 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr19_+_25504645 1.01 ENSDART00000143292
collagen, type XXVIII, alpha 1a
chr6_+_41096058 1.01 ENSDART00000028373
FK506 binding protein 5
chr22_-_10470663 1.01 ENSDART00000143352
osteomodulin
chr1_+_55137943 1.01 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
myoglobin
chr5_+_23118470 1.01 ENSDART00000149893
neurite extension and migration factor a
chr21_+_39100289 1.00 ENSDART00000075958
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr13_+_29462249 1.00 ENSDART00000147903
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr23_+_2778813 1.00 ENSDART00000142621
DNA topoisomerase I
chr15_-_12011202 1.00 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
chr17_+_15845765 1.00 ENSDART00000130881
ENSDART00000074936
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr12_+_45676667 1.00 ENSDART00000016553
si:ch73-111m19.2
chr10_+_38775408 0.99 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr19_-_7406933 0.99 ENSDART00000151137
oxidation resistance 1b
chr21_-_22543611 0.99 ENSDART00000177084
myosin VB
chr17_-_200316 0.98 ENSDART00000190561

chr2_-_37889111 0.98 ENSDART00000168939
ENSDART00000098529
mannose binding lectin 2
chr21_-_25722834 0.98 ENSDART00000101208
abhydrolase domain containing 11
chr11_-_11266882 0.97 ENSDART00000020256
lengsin, lens protein with glutamine synthetase domain
chr4_-_19982119 0.97 ENSDART00000169248
dopamine receptor D4 related sequence
chr17_+_15433671 0.97 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr21_-_37889727 0.97 ENSDART00000163612
ENSDART00000180958
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr7_-_38644287 0.96 ENSDART00000182307
six-cysteine containing astacin protease 3
chr6_+_27667359 0.95 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr9_+_4609746 0.95 ENSDART00000075420
reprimo, TP53 dependent G2 arrest mediator candidate a
chr22_+_17828267 0.95 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr7_+_61184104 0.94 ENSDART00000110671
zgc:194930
chr10_-_43334914 0.93 ENSDART00000146660
ENSDART00000190288
hyaluronan and proteoglycan link protein 1b
chr19_-_27966780 0.93 ENSDART00000110016
ubiquitin-conjugating enzyme E2Q family-like 1
chr25_-_32311048 0.92 ENSDART00000181806
ENSDART00000086334

chr21_-_19018455 0.92 ENSDART00000080256
neurofilament, medium polypeptide a
chr20_-_50049099 0.92 ENSDART00000123634
NADH:ubiquinone oxidoreductase subunit B1
chr19_+_48111285 0.91 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr9_-_44948488 0.91 ENSDART00000059228
villin 1
chr23_+_6272638 0.90 ENSDART00000190366
synaptotagmin IIa
chr8_+_50946379 0.90 ENSDART00000139649
beta-2-microglobulin, like
chr18_+_50276653 0.90 ENSDART00000192120
si:dkey-105e17.1
chr18_-_39473055 0.89 ENSDART00000122930
secretogranin III
chr25_+_31227747 0.89 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0060406 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.7 2.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.6 0.6 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.6 3.4 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.5 1.6 GO:0060292 long term synaptic depression(GO:0060292)
0.5 2.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.5 1.6 GO:0015824 proline transport(GO:0015824)
0.5 3.3 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.4 4.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.4 2.7 GO:0034389 lipid particle organization(GO:0034389)
0.4 1.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 1.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.7 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 2.0 GO:0010269 response to selenium ion(GO:0010269)
0.3 1.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 4.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 3.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 2.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 0.8 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 1.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.3 1.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 0.8 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.3 1.0 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.3 0.8 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.3 1.0 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 2.0 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.2 0.7 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.2 1.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 4.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.7 GO:0044321 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.2 4.8 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.2 0.9 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.2 0.7 GO:2000648 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.2 1.5 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.6 GO:0042245 RNA repair(GO:0042245)
0.2 0.8 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.2 0.6 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.2 1.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2 0.9 GO:0043420 anthranilate metabolic process(GO:0043420)
0.2 2.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 0.5 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.2 0.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.7 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.2 1.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.5 GO:0035046 pronuclear migration(GO:0035046)
0.2 0.7 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 1.8 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 0.5 GO:0030237 female sex determination(GO:0030237)
0.2 0.5 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.2 1.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.9 GO:0022410 circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle(GO:0042745)
0.1 1.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.1 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.4 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858)
0.1 1.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 2.3 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.5 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 1.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.3 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.1 GO:0090036 positive regulation of protein kinase A signaling(GO:0010739) regulation of protein kinase C signaling(GO:0090036)
0.1 0.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 1.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.5 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.3 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.6 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.5 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 1.4 GO:0001964 startle response(GO:0001964)
0.1 2.1 GO:0014823 response to activity(GO:0014823)
0.1 0.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.9 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.6 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.5 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.4 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 4.5 GO:0050432 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) catecholamine secretion(GO:0050432) regulation of catecholamine secretion(GO:0050433)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.5 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.5 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.6 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.3 GO:0009750 response to fructose(GO:0009750)
0.1 2.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.3 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 1.3 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.5 GO:0019233 sensory perception of pain(GO:0019233)
0.1 0.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.3 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.2 GO:0036314 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 1.3 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.1 1.5 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.5 GO:0036268 swimming(GO:0036268)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0006569 tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.1 1.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.2 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 4.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.7 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.0 GO:0006265 DNA topological change(GO:0006265)
0.1 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.6 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.1 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.2 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.4 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.5 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 2.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.0 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 2.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0071467 cellular response to pH(GO:0071467)
0.0 5.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 2.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.3 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.2 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.0 0.3 GO:0070640 cellular response to nutrient(GO:0031670) vitamin D3 metabolic process(GO:0070640) cellular response to vitamin(GO:0071295) cellular response to vitamin D(GO:0071305)
0.0 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.8 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.8 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.8 GO:0046849 bone remodeling(GO:0046849)
0.0 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 4.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.7 GO:0046113 pyrimidine nucleobase catabolic process(GO:0006208) nucleobase catabolic process(GO:0046113)
0.0 0.7 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0010543 regulation of platelet activation(GO:0010543) regulation of platelet aggregation(GO:0090330)
0.0 1.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0001881 receptor recycling(GO:0001881)
0.0 0.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 2.5 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 1.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 1.9 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 1.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 3.3 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.0 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) multicellular organismal water homeostasis(GO:0050891)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.1 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0030073 insulin secretion(GO:0030073)
0.0 0.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.6 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.0 0.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.2 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 2.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.3 GO:0007631 feeding behavior(GO:0007631)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.9 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0001840 neural plate development(GO:0001840)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366)
0.0 1.3 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 1.5 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 0.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.1 GO:0006909 phagocytosis(GO:0006909)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.8 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0072676 lymphocyte migration(GO:0072676)
0.0 0.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.3 4.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.0 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.9 GO:0005883 neurofilament(GO:0005883)
0.2 0.9 GO:0032433 filopodium tip(GO:0032433)
0.2 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 6.4 GO:0043204 perikaryon(GO:0043204)
0.2 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 5.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 5.9 GO:0005861 troponin complex(GO:0005861)
0.1 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 5.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 7.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.9 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.5 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 4.6 GO:0030426 growth cone(GO:0030426)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 0.4 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.2 GO:0005948 acetolactate synthase complex(GO:0005948)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 7.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.8 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 3.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.7 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.6 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 2.5 GO:0034703 cation channel complex(GO:0034703)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 3.9 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.3 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.0 GO:0070195 growth hormone receptor complex(GO:0070195)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.5 4.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.4 4.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.4 2.5 GO:0032052 bile acid binding(GO:0032052)
0.4 1.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.4 3.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 5.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 1.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 3.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 2.7 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.2 3.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 4.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 1.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 1.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.7 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.2 1.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 3.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 0.8 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.2 1.9 GO:0016936 galactoside binding(GO:0016936)
0.2 2.6 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.8 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 1.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 0.8 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.2 0.5 GO:0016496 substance P receptor activity(GO:0016496)
0.2 0.5 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.2 0.8 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 4.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 5.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 0.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 3.9 GO:0008483 transaminase activity(GO:0008483)
0.1 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.5 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 2.2 GO:0030553 cGMP binding(GO:0030553)
0.1 2.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 1.0 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 3.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.8 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 1.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 2.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.1 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.1 0.4 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.3 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.8 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0004096 catalase activity(GO:0004096)
0.1 1.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 3.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 1.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 5.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0003984 acetolactate synthase activity(GO:0003984)
0.1 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.3 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 2.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.6 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.4 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.4 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 2.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 2.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 1.0 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 1.2 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.6 GO:0008009 chemokine activity(GO:0008009)
0.0 3.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.0 4.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.4 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 3.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 3.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.0 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.4 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 PID CONE PATHWAY Visual signal transduction: Cones
0.2 5.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 3.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.0 2.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis