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PRJEB1986: zebrafish developmental stages transcriptome

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Results for BX548005.1+smarcc2

Z-value: 1.49

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Transcription factors associated with BX548005.1+smarcc2

Gene Symbol Gene ID Gene Info
ENSDARG00000077946 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
ENSDARG00000110907 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smarcc2dr11_v1_chr6_+_39836474_39836474-0.918.4e-08Click!

Activity profile of BX548005.1+smarcc2 motif

Sorted Z-values of BX548005.1+smarcc2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_2725594 5.10 ENSDART00000152120
akirin 2
chr15_+_2857556 4.00 ENSDART00000157758
MRE11 homolog A, double strand break repair nuclease
chr20_-_2725930 3.59 ENSDART00000081643
akirin 2
chr11_+_29537756 3.56 ENSDART00000103388
wu:fi42e03
chr1_+_9153141 3.53 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr13_+_24402406 3.49 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr24_+_29352039 3.18 ENSDART00000101641
protein arginine methyltransferase 6
chr16_+_27442549 3.11 ENSDART00000015688
inversin
chr3_-_26184018 3.07 ENSDART00000191604
si:ch211-11k18.4
chr11_-_16021424 3.06 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
chr3_-_26183699 3.01 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr19_-_41518922 2.97 ENSDART00000164483
ENSDART00000062080
chromatin accessibility complex 1
chr7_+_2455344 2.91 ENSDART00000172942
si:dkey-125e8.4
chr25_-_3347418 2.87 ENSDART00000082385
golgi transport 1Bb
chr1_+_24557414 2.81 ENSDART00000076519
dCTP pyrophosphatase 1
chr11_-_35171162 2.80 ENSDART00000017393
TRAF-interacting protein
chr22_+_22302614 2.75 ENSDART00000049434
secretory carrier membrane protein 4
chr11_-_35171768 2.73 ENSDART00000192896
TRAF-interacting protein
chr1_+_41131481 2.73 ENSDART00000145272
low density lipoprotein receptor-related protein associated protein 1
chr24_-_37680917 2.72 ENSDART00000131342
ankyrin repeat and sterile alpha motif domain containing 3
chr8_+_26410539 2.71 ENSDART00000168780
interferon-related developmental regulator 2
chr1_+_5485799 2.64 ENSDART00000022307
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_-_12764360 2.58 ENSDART00000003418
breast cancer metastasis-suppressor 1-like a
chr24_+_21092156 2.51 ENSDART00000028542
coiled-coil domain containing 191
chr14_+_989733 2.51 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr9_+_37754845 2.47 ENSDART00000100592
protein disulfide isomerase family A, member 5
chr2_-_25140022 2.43 ENSDART00000134543
neutral cholesterol ester hydrolase 1a
chr16_-_41535690 2.40 ENSDART00000102662
ribonuclease P/MRP 25 subunit-like
chr19_-_17210760 2.40 ENSDART00000007906
stathmin 1a
chr18_-_27316599 2.40 ENSDART00000028294
zgc:56106
chr17_-_18797245 2.35 ENSDART00000045991
vaccinia related kinase 1
chr8_+_48942470 2.29 ENSDART00000005464
ENSDART00000132035
retention in endoplasmic reticulum sorting receptor 1
chr3_+_31058464 2.28 ENSDART00000153381
si:dkey-66i24.7
chr8_-_16725959 2.28 ENSDART00000183593
DEP domain containing 1a
chr18_-_18587745 2.27 ENSDART00000191973
splicing factor 3b, subunit 3
chr6_-_39700965 2.25 ENSDART00000156645
extra spindle pole bodies like 1, separase
chr9_-_23242684 2.20 ENSDART00000053282
ENSDART00000179770
cyclin T2a
chr13_+_31390313 2.16 ENSDART00000111477
ENSDART00000137291
si:dkey-15f17.8
chr8_-_36554675 2.15 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr25_+_3347461 2.15 ENSDART00000104888
solute carrier family 35, member B4
chr1_+_53919110 2.14 ENSDART00000020680
nucleoporin 133
chr20_-_28842524 2.12 ENSDART00000046035
ENSDART00000139843
ENSDART00000129858
ENSDART00000137425
ENSDART00000135720
myc associated factor X
chr8_-_18613948 2.12 ENSDART00000089172
coproporphyrinogen oxidase
chr16_-_27442344 2.11 ENSDART00000027545
endoplasmic reticulum protein 44
chr18_-_38245062 2.10 ENSDART00000189092
N-acetyltransferase 10
chr25_+_9013342 2.09 ENSDART00000154207
ENSDART00000153705
im:7145024
chr13_+_28785814 2.07 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr6_-_58975010 2.07 ENSDART00000144911
ENSDART00000144514
methionyl-tRNA synthetase
chr16_-_39267185 2.06 ENSDART00000058550
ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1 like
chr23_+_5104743 2.04 ENSDART00000123191
ubiquitin-conjugating enzyme E2T (putative)
chr18_-_38244871 2.03 ENSDART00000076399
N-acetyltransferase 10
chr19_-_17210928 2.02 ENSDART00000164683
stathmin 1a
chr8_+_48943009 1.98 ENSDART00000180763
retention in endoplasmic reticulum sorting receptor 1
chr18_+_5308392 1.97 ENSDART00000179072
deoxyuridine triphosphatase
chr15_-_44052927 1.96 ENSDART00000166209
wu:fb44b02
chr9_-_29579908 1.94 ENSDART00000140876
centromere protein J
chr4_+_9592486 1.91 ENSDART00000080829
heat shock protein 14
chr18_+_29898955 1.91 ENSDART00000064080
centromere protein N
chr14_-_12106603 1.85 ENSDART00000054619
phosphoribosyl pyrophosphate synthetase 1B
chr22_+_25088999 1.83 ENSDART00000158225
ribosome binding protein 1b
chr9_+_30478768 1.80 ENSDART00000101097
acid phosphatase 6, lysophosphatidic
chr7_-_26627252 1.80 ENSDART00000164050
ENSDART00000159826
PHD finger protein 23b
chr15_-_34001000 1.79 ENSDART00000180464
si:dkey-30e9.7
chr17_+_43659940 1.79 ENSDART00000145738
ENSDART00000075619
2-aminoethanethiol (cysteamine) dioxygenase b
chr6_+_8652310 1.79 ENSDART00000105098
ubiquitin specific peptidase 40
chr23_+_2421313 1.79 ENSDART00000126038
t-complex 1
chr3_+_12554801 1.75 ENSDART00000167177
cyclin F
chr21_+_8198652 1.74 ENSDART00000011096
nuclear receptor subfamily 6, group A, member 1b
chr6_-_50730749 1.74 ENSDART00000157153
ENSDART00000110441
phosphatidylinositol glycan anchor biosynthesis, class U
chr5_-_10082244 1.73 ENSDART00000036421
checkpoint kinase 2
chr5_-_26170225 1.73 ENSDART00000146363
ENSDART00000017696
family with sequence similarity 151, member B
chr9_+_56232548 1.72 ENSDART00000099276
CCR4-NOT transcription complex, subunit 11
chr14_-_4321874 1.71 ENSDART00000042672
GUF1 homolog, GTPase
chr4_-_14954029 1.70 ENSDART00000038642
solute carrier family 26 (anion exchanger), member 5
chr3_+_24060454 1.69 ENSDART00000143088
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr2_+_27394798 1.67 ENSDART00000115071
selenoprotein P2
chr8_-_48847772 1.67 ENSDART00000122458
WD repeat containing, antisense to TP73
chr21_-_26071773 1.65 ENSDART00000141382
RAB34, member RAS oncogene family b
chr22_-_3152357 1.65 ENSDART00000170983
lamin B2
chr15_+_37589698 1.63 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr16_+_9762261 1.63 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr23_+_2421689 1.62 ENSDART00000180200
t-complex 1
chr15_+_8767650 1.61 ENSDART00000033871
adaptor-related protein complex 2, sigma 1 subunit
chr19_+_15521997 1.61 ENSDART00000003164
protein phosphatase 1, regulatory subunit 8a
chr23_+_20640484 1.61 ENSDART00000054691
ubiquitin-like modifier activating enzyme 1
chr2_+_27394979 1.59 ENSDART00000170495
selenoprotein P2
chr18_-_16953978 1.59 ENSDART00000100126
A kinase (PRKA) interacting protein 1
chr8_+_12951155 1.58 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr19_+_26072624 1.57 ENSDART00000147627
jumonji, AT rich interactive domain 2b
chr10_+_8091144 1.56 ENSDART00000143848
ENSDART00000075485
SUB1 homolog, transcriptional regulator a
chr7_+_71683853 1.55 ENSDART00000163002
elastin microfibril interfacer 2b
chr16_-_55259199 1.55 ENSDART00000161130
IQ motif containing GTPase activating protein 3
chr11_-_33868881 1.54 ENSDART00000163295
ENSDART00000172633
ENSDART00000171439
si:ch211-227n13.3
chr5_-_67349916 1.54 ENSDART00000144092
MLX interacting protein
chr25_-_8625601 1.54 ENSDART00000155280
zgc:153343
chr3_+_27665160 1.53 ENSDART00000103660
chloride channel 7
chr21_+_13327527 1.53 ENSDART00000114294
small nuclear ribonucleoprotein D3 polypeptide, like
chr3_+_36646054 1.53 ENSDART00000170013
ENSDART00000159948
G1 to S phase transition 1, like
chr1_-_51720633 1.51 ENSDART00000045894
ribonuclease H2, subunit A
chr20_+_5985329 1.48 ENSDART00000165489
centrosomal protein 128
chr25_+_20715950 1.46 ENSDART00000180223
ERGIC and golgi 2
chr4_+_17327704 1.46 ENSDART00000016075
ENSDART00000133160
nucleoporin 37
chr5_-_41142467 1.45 ENSDART00000129415
zinc finger RNA binding protein
chr13_-_24745288 1.44 ENSDART00000031564
SWI5-dependent homologous recombination repair protein 1
chr20_-_3997531 1.44 ENSDART00000092217
tetratricopeptide repeat domain 13
chr24_+_42004640 1.43 ENSDART00000171380
DNA topoisomerase I mitochondrial
chr20_-_31743817 1.41 ENSDART00000137679
SAM and SH3 domain containing 1a
chr14_+_30774894 1.40 ENSDART00000023054
atlastin 3
chr23_-_20133994 1.39 ENSDART00000004871
leucine rich repeat containing 23
chr8_+_49936585 1.39 ENSDART00000098707
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr20_-_16849306 1.38 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr4_-_14954327 1.38 ENSDART00000182729
solute carrier family 26 (anion exchanger), member 5
chr22_-_24285432 1.38 ENSDART00000164083
si:ch211-117l17.4
chr10_-_44306636 1.37 ENSDART00000191068
cyclin dependent kinase 2 associated protein 1
chr1_+_35494837 1.36 ENSDART00000140724
GRB2-associated binding protein 1
chr18_-_46369516 1.35 ENSDART00000018163
interferon regulatory factor 2 binding protein 1
chr8_+_31016180 1.34 ENSDART00000130870
ENSDART00000143604
outer dense fiber of sperm tails 2b
chr13_+_39315881 1.34 ENSDART00000135999
si:dkey-85a20.4
chr13_-_15929402 1.34 ENSDART00000090273
tubulin tyrosine ligase
chr2_+_16710889 1.33 ENSDART00000017852
UBX domain protein 7
chr14_-_26411918 1.33 ENSDART00000020582
transmembrane p24 trafficking protein 9
chr8_-_36618073 1.31 ENSDART00000047912
G patch domain and KOW motifs
chr6_-_6993046 1.31 ENSDART00000053304
si:ch211-114n24.6
chr19_-_8536474 1.31 ENSDART00000139715
dolichyl-phosphate mannosyltransferase polypeptide 3
chr19_+_627899 1.29 ENSDART00000148508
telomerase reverse transcriptase
chr12_+_8474868 1.28 ENSDART00000062858
2-aminoethanethiol (cysteamine) dioxygenase a
chr22_-_506522 1.28 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr21_-_21020708 1.27 ENSDART00000064032
eukaryotic translation initiation factor 4E binding protein 1
chr22_+_22888 1.26 ENSDART00000082471
microfibril associated protein 2
chr2_+_36608387 1.26 ENSDART00000159541
p21 protein (Cdc42/Rac)-activated kinase 2a
chr9_-_29985390 1.25 ENSDART00000134157
interleukin 1 receptor accessory protein-like 1a
chr5_+_15495351 1.25 ENSDART00000111646
ENSDART00000114446
SDS3 homolog, SIN3A corepressor complex component
chr20_+_14789305 1.25 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr13_+_33655404 1.24 ENSDART00000023379
mitochondrial genome maintenance exonuclease 1
chr16_+_31921812 1.24 ENSDART00000176928
ENSDART00000193733
ribosomal protein S9
chr3_+_3681116 1.24 ENSDART00000109618
ADP-ribosyltransferase 4 (Dombrock blood group)
chr4_-_22363709 1.23 ENSDART00000037670
origin recognition complex, subunit 5
chr7_+_7696665 1.22 ENSDART00000091099
INO80 complex subunit B
chr8_+_23381892 1.22 ENSDART00000180950
ENSDART00000063010
ENSDART00000074241
ENSDART00000142783
microtubule-associated protein, RP/EB family, member 1a
chr21_+_25802190 1.22 ENSDART00000128987
neurofibromin 2b (merlin)
chr22_+_23546926 1.21 ENSDART00000157940
abnormal spindle microtubule assembly
chr16_+_46684855 1.20 ENSDART00000058325
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr18_+_46162204 1.18 ENSDART00000113545
ENSDART00000147556
zgc:113340
chr9_+_29985010 1.18 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr18_-_3166726 1.17 ENSDART00000165002
aquaporin 11
chr12_-_28363111 1.16 ENSDART00000016283
ENSDART00000164156
proteasome 26S subunit, non-ATPase 11b
chr13_-_32626247 1.15 ENSDART00000100663
WD repeat domain 35
chr20_-_36809059 1.14 ENSDART00000062925
solute carrier family 25, member 27
chr2_+_31308587 1.14 ENSDART00000027090
clusterin-like 1 (retinal)
chr5_-_41142768 1.13 ENSDART00000074789
zinc finger RNA binding protein
chr24_+_37709191 1.10 ENSDART00000066558
2,4-dienoyl CoA reductase 2, peroxisomal
chr11_+_16040517 1.10 ENSDART00000111284
angiotensin II receptor-associated protein
chr7_-_38087865 1.09 ENSDART00000052366
CCAAT/enhancer binding protein (C/EBP), alpha
chr2_-_1468258 1.09 ENSDART00000114431
glycosylphosphatidylinositol anchor attachment 1
chr15_+_15516612 1.09 ENSDART00000016024
tnf receptor-associated factor 4a
chr20_-_18313864 1.09 ENSDART00000015479
proteasome subunit alpha 8
chr8_-_11988065 1.07 ENSDART00000005140
mediator complex subunit 27
chr15_-_23442891 1.07 ENSDART00000059376
ubiquitination factor E4A (UFD2 homolog, yeast)
chr3_+_1219344 1.06 ENSDART00000161945
ribosomal RNA processing 7 homolog A
chr15_-_29556757 1.06 ENSDART00000060049
heat shock protein 70 family, member 13
chr3_+_27664864 1.04 ENSDART00000126533
ENSDART00000180848
chloride channel 7
chr19_+_48018802 1.04 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr16_+_31922065 1.04 ENSDART00000131661
ENSDART00000144194
ENSDART00000145510
ribosomal protein S9
chr16_-_27161410 1.03 ENSDART00000177503

chr25_+_20716176 1.03 ENSDART00000073651
ERGIC and golgi 2
chr23_+_33947874 1.03 ENSDART00000136104
si:ch211-148l7.4
chr5_-_32890807 1.02 ENSDART00000007512
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr23_-_14216506 1.02 ENSDART00000019620
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr23_-_26227805 1.02 ENSDART00000158082

chr16_+_30604387 1.01 ENSDART00000058785
family with sequence similarity 210, member Ab
chr4_-_1818315 1.00 ENSDART00000067433
ubiquitin-conjugating enzyme E2Nb
chr7_-_17712665 1.00 ENSDART00000149047
multiple endocrine neoplasia I
chr21_+_21791799 1.00 ENSDART00000151759
sialidase 3 (membrane sialidase), tandem duplicate 1
chr13_-_33654931 0.99 ENSDART00000020350
sorting nexin 5
chr4_+_25912654 0.99 ENSDART00000109508
ENSDART00000134218
vezatin, adherens junctions transmembrane protein
chr18_+_8320165 0.98 ENSDART00000092053
choline kinase beta
chr5_+_60590796 0.97 ENSDART00000159859
transmembrane protein 132E
chr10_+_36441124 0.95 ENSDART00000185626
ubiquitin specific peptidase like 1
chr16_-_34285106 0.95 ENSDART00000044235
phosphatase and actin regulator 4b
chr17_-_24521382 0.94 ENSDART00000092948
pellino E3 ubiquitin protein ligase 1b
chr24_+_19591893 0.93 ENSDART00000152026
solute carrier organic anion transporter family member 5A1a
chr5_-_56948058 0.93 ENSDART00000083074
ENSDART00000191028
si:ch211-127d4.3
chr20_+_9474841 0.93 ENSDART00000053847
RAD51 paralog B
chr13_-_33639050 0.93 ENSDART00000133073
ribosome binding protein 1a
chr2_-_16159491 0.93 ENSDART00000110059
vav 3 guanine nucleotide exchange factor b
chr16_+_42471455 0.92 ENSDART00000166640
si:ch211-215k15.5
chr15_+_44053244 0.92 ENSDART00000059550
leucine rich repeat containing 51
chr23_+_33752275 0.92 ENSDART00000007260
si:ch211-210c8.6
chr3_+_4502066 0.91 ENSDART00000088610
RAN GTPase activating protein 1a
chr2_-_13254821 0.91 ENSDART00000022621
3-ketodihydrosphingosine reductase
chr20_+_14789148 0.91 ENSDART00000164761
transmembrane p24 trafficking protein 5
chr15_-_37589600 0.91 ENSDART00000154641
proline and serine rich 3
chr12_+_36109507 0.91 ENSDART00000175409
mitogen-activated protein kinase kinase 6
chr25_+_36311333 0.90 ENSDART00000190174
histone cluster 1 H2A family member 2
chr13_-_42400647 0.89 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr7_-_24022340 0.88 ENSDART00000149133
cell death-inducing DFFA-like effector b
chr11_+_18612421 0.87 ENSDART00000110621
nuclear receptor coactivator 3
chr4_+_25912308 0.86 ENSDART00000167845
ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr11_+_34921492 0.86 ENSDART00000128070
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr6_-_34938678 0.86 ENSDART00000186689
ENSDART00000131610
SERPINE1 mRNA binding protein 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of BX548005.1+smarcc2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.8 3.2 GO:0034969 histone arginine methylation(GO:0034969)
0.8 3.1 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.8 3.1 GO:0019532 oxalate transport(GO:0019532)
0.6 4.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 2.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.5 2.7 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.5 3.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.5 2.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.5 1.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.5 2.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.5 4.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 2.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.5 1.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4 1.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 1.8 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.4 1.3 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.4 1.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.3 3.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 1.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 2.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.3 1.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 2.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 1.9 GO:0061511 centriole elongation(GO:0061511)
0.3 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.3 2.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 1.0 GO:0006272 leading strand elongation(GO:0006272)
0.3 1.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 2.2 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 1.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 0.6 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.2 3.0 GO:0042026 protein refolding(GO:0042026)
0.2 1.4 GO:0032475 otolith formation(GO:0032475)
0.2 1.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 1.0 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.2 0.9 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 2.8 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.4 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 0.7 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.8 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 1.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.2 1.2 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.4 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 1.6 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 2.9 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.1 1.3 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 4.1 GO:0000154 rRNA modification(GO:0000154)
0.1 2.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 1.9 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.8 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 8.7 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.1 1.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 2.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.7 GO:0030728 ovulation(GO:0030728)
0.1 0.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 3.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 1.0 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 2.2 GO:0051307 meiotic chromosome separation(GO:0051307)
0.1 5.2 GO:0016575 histone deacetylation(GO:0016575)
0.1 4.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 2.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.6 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.9 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.3 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 1.8 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 1.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.9 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 3.5 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 2.1 GO:0048264 determination of ventral identity(GO:0048264)
0.1 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.1 GO:0009409 response to cold(GO:0009409)
0.1 1.1 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.2 GO:0043687 post-translational protein modification(GO:0043687)
0.1 2.1 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.3 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.1 2.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.1 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.5 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.6 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 3.5 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 0.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.1 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 0.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 1.7 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.6 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.8 GO:0039021 regulation of protein stability(GO:0031647) pronephric glomerulus development(GO:0039021)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 2.8 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 1.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 2.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.5 GO:0032438 melanosome organization(GO:0032438)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.9 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 1.5 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.7 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 1.8 GO:1901653 cellular response to peptide hormone stimulus(GO:0071375) cellular response to peptide(GO:1901653)
0.0 2.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 3.0 GO:0006310 DNA recombination(GO:0006310)
0.0 0.2 GO:2000765 regulation of cytoplasmic translation(GO:2000765) negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0043200 response to amino acid(GO:0043200) cellular response to amino acid stimulus(GO:0071230)
0.0 0.6 GO:1903038 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 1.5 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.7 GO:0021549 cerebellum development(GO:0021549)
0.0 0.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.0 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 1.3 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.1 GO:0090504 epiboly(GO:0090504)
0.0 0.6 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.0 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0030870 Mre11 complex(GO:0030870)
0.6 1.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.5 2.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 1.9 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.5 1.4 GO:0031417 NatC complex(GO:0031417)
0.4 3.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 1.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.4 1.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.1 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.3 2.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 4.0 GO:0031010 ISWI-type complex(GO:0031010)
0.3 3.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 3.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.3 1.5 GO:0018444 translation release factor complex(GO:0018444)
0.3 2.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 2.4 GO:0032021 NELF complex(GO:0032021)
0.3 2.3 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 2.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 5.2 GO:0070822 Sin3-type complex(GO:0070822)
0.2 1.8 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.2 0.6 GO:0097541 axonemal basal plate(GO:0097541)
0.2 4.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 1.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 2.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 1.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 2.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.8 GO:0000938 GARP complex(GO:0000938)
0.1 1.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0030914 STAGA complex(GO:0030914)
0.1 4.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.2 GO:0051233 spindle midzone(GO:0051233)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 5.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 4.6 GO:0000922 spindle pole(GO:0000922)
0.1 1.0 GO:0015030 Cajal body(GO:0015030)
0.1 3.9 GO:0005814 centriole(GO:0005814)
0.1 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 3.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 3.2 GO:0005795 Golgi stack(GO:0005795)
0.0 1.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 8.0 GO:0000785 chromatin(GO:0000785)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 6.0 GO:0005730 nucleolus(GO:0005730)
0.0 6.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.3 GO:0044420 extracellular matrix component(GO:0044420)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.7 3.3 GO:0008430 selenium binding(GO:0008430)
0.6 3.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.5 2.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.5 2.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.5 1.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.5 2.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 2.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.4 1.3 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.4 1.3 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.4 1.4 GO:0033149 FFAT motif binding(GO:0033149)
0.3 2.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 1.6 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.3 1.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 0.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 2.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 1.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 2.0 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.2 1.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 3.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.0 GO:0032183 SUMO binding(GO:0032183)
0.2 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 1.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 1.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 0.6 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 3.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 5.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.8 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.1 4.1 GO:0000049 tRNA binding(GO:0000049)
0.1 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.9 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.1 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 1.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.2 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 3.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.9 GO:0017022 myosin binding(GO:0017022)
0.0 1.9 GO:0043022 ribosome binding(GO:0043022)
0.0 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.8 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 4.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 12.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 4.1 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.6 GO:0046332 SMAD binding(GO:0046332)
0.0 1.2 GO:0060090 binding, bridging(GO:0060090)
0.0 0.2 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 PID ATM PATHWAY ATM pathway
0.2 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 2.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.0 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.5 PID ATR PATHWAY ATR signaling pathway
0.1 4.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 1.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.3 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 4.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 3.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 2.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 5.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 3.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 1.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 2.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 4.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 2.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 3.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.7 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 2.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases