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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for znf384l

Z-value: 1.32

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Transcription factors associated with znf384l

Gene Symbol Gene ID Gene Info
ENSDARG00000001015 zinc finger protein 384 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf384ldr11_v1_chr19_-_6983002_6983002-0.205.6e-02Click!

Activity profile of znf384l motif

Sorted Z-values of znf384l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_1838164 13.46 ENSDART00000006013
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5
chr16_-_23346095 12.61 ENSDART00000160546
si:dkey-247k7.2
chr16_+_35924188 11.75 ENSDART00000165847
SH3 domain containing 21
chr22_-_15593824 10.16 ENSDART00000123125
tropomyosin 4a
chr16_-_21038015 10.07 ENSDART00000059239
sorting nexin 10b
chr25_+_8356707 9.25 ENSDART00000153708
mucin 5.1, oligomeric mucus/gel-forming
chr17_-_8862424 9.19 ENSDART00000064633
NK-lysin tandem duplicate 4
chr2_-_20923864 8.78 ENSDART00000006870
prostaglandin-endoperoxide synthase 2a
chr7_-_31441420 8.70 ENSDART00000075398
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr12_-_4249000 8.42 ENSDART00000059298
zgc:92313
chr14_-_12071679 8.09 ENSDART00000165581
thymosin beta 1
chr5_+_26212621 7.67 ENSDART00000134432
occludin b
chr8_+_19356072 7.67 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr1_-_33380011 7.50 ENSDART00000141347
ENSDART00000136383
CD99 molecule
chr3_-_22228602 7.46 ENSDART00000017750
myosin, light chain 4, alkali; atrial, embryonic
chr9_-_45602978 7.33 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr12_+_20336070 7.26 ENSDART00000066385
zgc:163057
chr3_+_23221047 7.13 ENSDART00000009393
collagen, type I, alpha 1a
chr4_+_7677318 7.02 ENSDART00000149218
ELK3, ETS-domain protein
chr15_+_46356879 6.93 ENSDART00000154388
wu:fb18f06
chr6_-_33075576 6.93 ENSDART00000154017
si:dkey-170g13.2
chr16_-_46664465 6.91 ENSDART00000135364
transmembrane protein 176l.4
chr14_+_15622817 6.90 ENSDART00000158624
si:dkey-203a12.9
chr19_-_15281996 6.77 ENSDART00000103784
endothelin 2
chr19_+_7043634 6.67 ENSDART00000133954
major histocompatibility complex class I UKA
chr11_-_42730063 6.54 ENSDART00000169776
si:ch73-106k19.2
chr15_-_46779934 6.49 ENSDART00000085136
chloride channel 2c
chr17_+_24851951 6.49 ENSDART00000180746
connexin 35.4
chr19_-_25519612 6.47 ENSDART00000133150
si:dkey-202e17.1
chr19_-_25005609 6.46 ENSDART00000151129
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 2
chr19_-_13808630 6.42 ENSDART00000166895
ENSDART00000187670
connective tissue growth factor b
chr14_-_12071447 6.28 ENSDART00000166116
thymosin beta 1
chr3_-_39488482 6.27 ENSDART00000135192
zgc:100868
chr22_-_17671348 6.26 ENSDART00000137995
tight junction protein 3
chr1_-_59116617 6.18 ENSDART00000137471
ENSDART00000140490
si:zfos-2330d3.7
chr19_+_5640504 6.14 ENSDART00000179987
alpha(1,3)fucosyltransferase gene 2
chr15_-_34892664 6.14 ENSDART00000153787
ENSDART00000099721
ring finger protein 183
chr19_-_25519310 6.03 ENSDART00000089882
si:dkey-202e17.1
chr10_-_17988779 5.98 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
chr7_-_38659477 5.77 ENSDART00000138071
nephrosin
chr16_-_12319822 5.71 ENSDART00000127453
ENSDART00000184526
transient receptor potential cation channel, subfamily V, member 6
chr2_+_36112273 5.62 ENSDART00000191315
T-cell receptor alpha joining 35
chr19_-_977849 5.52 ENSDART00000172303

chr1_-_59096190 5.52 ENSDART00000149436
ENSDART00000191532
wu:fj11g02
si:zfos-2330d3.1
chr20_-_35557902 5.50 ENSDART00000134753
adhesion G protein-coupled receptor F7
chr17_+_28103675 5.41 ENSDART00000188078
zgc:91908
chr5_-_68876211 5.39 ENSDART00000097254
surfactant protein Bb
chr7_-_7398350 5.38 ENSDART00000012637
zgc:101810
chr3_-_20091964 5.34 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr19_+_7045033 5.30 ENSDART00000146579
major histocompatibility complex class I UKA
chr25_+_35502552 5.21 ENSDART00000189612
ENSDART00000058443
fin bud initiation factor a
chr16_-_11932923 5.19 ENSDART00000103975
CD4-1 molecule
chr9_+_6578580 5.13 ENSDART00000061577
four and a half LIM domains 2a
chr10_+_8875195 5.13 ENSDART00000141045
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr18_+_35861930 5.10 ENSDART00000185223
protein phosphatase 1, regulatory subunit 13 like
chr25_+_19734038 5.06 ENSDART00000067354
zgc:101783
chr1_+_1904419 5.05 ENSDART00000142874
si:ch211-132g1.4
chr8_-_46455874 5.04 ENSDART00000146985
sulfotransferase family 1, cytosolic sulfotransferase 7
chr6_-_47506351 5.02 ENSDART00000128700
im:7151449
chr6_+_23809163 4.98 ENSDART00000170402
glutamate-ammonia ligase (glutamine synthase) b
chr17_+_25444605 4.95 ENSDART00000149804
chloride intracellular channel 4
chr2_+_45191049 4.95 ENSDART00000165392
chemokine (C-C motif) ligand 20a, duplicate 3
chr5_-_6567464 4.93 ENSDART00000184985
tankyrase 1 binding protein 1
chr23_+_42813415 4.90 ENSDART00000055577
myosin, light chain 9a, regulatory
chr11_-_21404358 4.89 ENSDART00000129062
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr11_-_20096018 4.84 ENSDART00000030420
opioid growth factor receptor-like 2
chr1_+_9994811 4.83 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
chr12_-_30548244 4.82 ENSDART00000193616
zgc:158404
chr11_-_7261717 4.78 ENSDART00000128959
zgc:113223
chr3_+_2971852 4.75 ENSDART00000059271

chr1_+_41478345 4.73 ENSDART00000134626
docking protein 1a
chr4_+_7817996 4.72 ENSDART00000166809
si:ch1073-67j19.1
chr21_+_25688388 4.66 ENSDART00000125709
bicaudal-D-related protein 2
chr7_-_2047639 4.65 ENSDART00000173892
si:cabz01007794.1
chr24_-_25096199 4.61 ENSDART00000185076
pleckstrin homology-like domain, family B, member 2b
chr15_-_20916251 4.58 ENSDART00000134053
ubiquitin specific peptidase 2a
chr2_+_23790748 4.52 ENSDART00000041877
cysteine-serine-rich nuclear protein 1a
chr6_-_29007493 4.51 ENSDART00000065139
growth factor independent 1A transcription repressor b
chr21_-_11646878 4.50 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr9_-_33081978 4.49 ENSDART00000100918
zgc:172053
chr24_+_39990695 4.47 ENSDART00000040281

chr23_-_5818992 4.47 ENSDART00000148730
cysteine and glycine-rich protein 1a
chr9_+_10692905 4.47 ENSDART00000061499
chemokine (C-X-C motif), receptor 4b
chr19_-_5345930 4.45 ENSDART00000066620
ENSDART00000151398
keratin type 1 c19e
chr2_+_36109002 4.45 ENSDART00000158978
T-cell receptor alpha joining 28
chr8_-_23599096 4.44 ENSDART00000183096
solute carrier family 38, member 5b
chr6_-_52675630 4.40 ENSDART00000083830
syndecan 4
chr13_-_21672131 4.38 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr7_-_52417060 4.36 ENSDART00000148579
myocardial zonula adherens protein
chr21_+_15723069 4.34 ENSDART00000149126
ENSDART00000130628
purinergic receptor P2X, ligand-gated ion channel, 4a
chr23_+_17865953 4.18 ENSDART00000014723
ENSDART00000140302
ENSDART00000144800
nascent polypeptide-associated complex alpha subunit
chr7_+_65673885 4.18 ENSDART00000169182
parvin, alpha b
chr2_-_37744951 4.08 ENSDART00000144807
myosin IXb
chr13_+_47810211 4.08 ENSDART00000122964
zmp:0000001006
chr8_+_21353878 4.07 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr16_+_33142734 4.05 ENSDART00000138244
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_58550291 4.02 ENSDART00000184983
ENSDART00000044803
POU class 2 homeobox 3
chr16_-_39570832 3.99 ENSDART00000039832
transforming growth factor beta receptor 2b
chr20_+_34130714 3.97 ENSDART00000135915
phospholipase A2, group IVAb (cytosolic, calcium-dependent)
chr16_+_19732543 3.95 ENSDART00000149901
ENSDART00000052927
twist family bHLH transcription factor 1b
chr17_-_6451801 3.95 ENSDART00000064700
alpha-L-fucosidase 2
chr14_+_4151379 3.94 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr8_+_11687254 3.90 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr18_-_35459996 3.89 ENSDART00000141023
inositol-trisphosphate 3-kinase Cb
chr21_+_30794351 3.87 ENSDART00000139486
zgc:158225
chr7_+_35238234 3.86 ENSDART00000178732
tubulin polymerization-promoting protein family member 3
chr16_+_38201840 3.84 ENSDART00000044971
myosin IE, b
chr3_-_4591643 3.82 ENSDART00000138144
finTRIM family, member 50
chr22_-_3344613 3.82 ENSDART00000165600
thromboxane A2 receptor
chr15_+_24563504 3.82 ENSDART00000140658
ENSDART00000130589
ENSDART00000045549
dehydrogenase/reductase (SDR family) member 13b
chr7_-_20241346 3.73 ENSDART00000173619
ENSDART00000127699
si:ch73-335l21.4
chr21_-_11996769 3.73 ENSDART00000143537
zgc:64106
chr5_-_4532516 3.71 ENSDART00000192398
cystatin 14b, tandem duplicate 1
chr7_-_26579465 3.69 ENSDART00000173820
si:dkey-62k3.6
chr7_+_2228276 3.68 ENSDART00000064294
si:dkey-187j14.4
chr2_-_43635777 3.65 ENSDART00000148633
integrin, beta 1b.1
chr10_-_43771447 3.65 ENSDART00000052307
arrestin domain containing 3b
chr12_-_44016898 3.64 ENSDART00000175304
si:dkey-201i2.4
chr3_+_3139240 3.63 ENSDART00000105014
si:dkey-30g5.1
chr6_+_36821621 3.60 ENSDART00000104157
transmembrane protein 45a
chr25_+_5035343 3.55 ENSDART00000011751
parvin, beta
chr1_+_52392511 3.54 ENSDART00000144025
si:ch211-217k17.8
chr13_-_15994419 3.53 ENSDART00000079724
ENSDART00000042377
ENSDART00000046079
ENSDART00000050481
ENSDART00000016430
IKAROS family zinc finger 1 (Ikaros)
chr8_-_46509194 3.47 ENSDART00000038924
sulfotransferase family 1, cytosolic sulfotransferase 1
chr17_+_25444323 3.46 ENSDART00000030691
chloride intracellular channel 4
chr3_+_32571929 3.43 ENSDART00000151025
si:ch73-248e21.1
chr23_-_14830627 3.42 ENSDART00000134659
Src-like-adaptor 2
chr8_+_22377936 3.41 ENSDART00000181548
si:dkey-23c22.5
chr16_-_30878521 3.41 ENSDART00000141403
DENN/MADD domain containing 3b
chr3_-_2091029 3.40 ENSDART00000141464
si:dkey-88j15.4
chr5_-_44286987 3.37 ENSDART00000184112
si:ch73-337l15.2
chr1_-_59102320 3.37 ENSDART00000193379
si:zfos-2330d3.7
chr9_-_14055959 3.33 ENSDART00000146675
fer-1-like family member 6
chr20_-_25369767 3.32 ENSDART00000180278
intersectin 2a
chr19_+_7124337 3.31 ENSDART00000031380
transporter associated with antigen processing, subunit type a
chr4_+_38550788 3.30 ENSDART00000157412
si:ch211-209n20.1
chr18_+_45645357 3.27 ENSDART00000010256
eukaryotic translation initiation factor 3, subunit M
chr12_-_44010532 3.27 ENSDART00000183875
si:ch211-182p11.1
chr12_+_30360579 3.23 ENSDART00000152900
si:ch211-225b10.3
chr18_+_8833251 3.23 ENSDART00000143519
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr18_-_49020066 3.22 ENSDART00000174394

chr18_+_20468157 3.21 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
damage-specific DNA binding protein 2
chr19_-_2861444 3.19 ENSDART00000169053
C-type lectin domain family 3, member Bb
chr20_-_34292607 3.11 ENSDART00000144705
hemicentin 1
chr8_+_8936912 3.10 ENSDART00000135958
si:dkey-83k24.5
chr19_-_24267410 3.09 ENSDART00000104083
S100 calcium binding protein V2
chr6_+_36878815 3.09 ENSDART00000192482
TRAF3 interacting protein 2-like
chr7_-_8738827 3.09 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
chr15_-_39971756 3.07 ENSDART00000063789
ribosomal protein S5
chr12_-_4841018 3.06 ENSDART00000166500
zgc:163073
chr9_-_4075620 3.06 ENSDART00000046903
myosin, light chain kinase a
chr2_+_43750899 3.01 ENSDART00000135836
Rho GTPase activating protein 12a
chr15_-_35960250 3.00 ENSDART00000186765
collagen, type IV, alpha 4
chr3_+_25121156 2.97 ENSDART00000025724
zgc:63831
chr25_+_11456696 2.97 ENSDART00000171408
si:ch73-141f14.1
chr15_+_7054754 2.96 ENSDART00000149800
forkhead box L2a
chr20_-_31067306 2.95 ENSDART00000014163
fibronectin type III domain containing 1
chr4_+_73606482 2.92 ENSDART00000150765
si:ch211-165i18.2
chr5_+_1589458 2.90 ENSDART00000167473

chr24_+_36636208 2.89 ENSDART00000139211
si:ch73-334d15.4
chr23_+_1276006 2.86 ENSDART00000162294
utrophin
chr3_+_57948377 2.85 ENSDART00000047418
notum, palmitoleoyl-protein carboxylesterase a
chr16_+_28383758 2.84 ENSDART00000059038
ENSDART00000141061
integrin, alpha 8
chr1_-_25177086 2.82 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr11_-_28050559 2.81 ENSDART00000136859
endothelin converting enzyme 1
chr6_-_49215790 2.80 ENSDART00000103376
ENSDART00000132347
ENSDART00000132131
ENSDART00000143252
ENSDART00000065033
nerve growth factor b (beta polypeptide)
chr8_-_32805214 2.80 ENSDART00000131597
zgc:194839
chr19_+_19786117 2.79 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr5_-_34609337 2.78 ENSDART00000145792
hexosaminidase B (beta polypeptide)
chr10_-_15053507 2.76 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr14_-_1355544 2.73 ENSDART00000060417
centrin 4
chr19_-_43639331 2.73 ENSDART00000138009
ENSDART00000086138
family with sequence similarity 83, member Hb
chr2_-_58183499 2.72 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
chr6_+_48206535 2.71 ENSDART00000075172
CTTNBP2 N-terminal like a
chr6_+_49052741 2.69 ENSDART00000011876
synaptonemal complex protein 1
chr3_-_54669185 2.68 ENSDART00000053106
sphingosine-1-phosphate receptor 2
chr8_-_14126646 2.68 ENSDART00000027225
biglycan a
chr20_+_37393134 2.67 ENSDART00000128321
adhesion G protein-coupled receptor G6
chr18_-_37355666 2.67 ENSDART00000098914
Yes-associated protein 1
chr15_+_19838458 2.66 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr5_-_28968964 2.65 ENSDART00000184936
ENSDART00000016628
family with sequence similarity 129, member Bb
chr1_+_20635190 2.65 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr13_-_42673978 2.64 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2
chr13_+_22264914 2.63 ENSDART00000060576
myozenin 1a
chr16_-_30903930 2.59 ENSDART00000143996
DENN/MADD domain containing 3b
chr21_-_20832482 2.59 ENSDART00000191928
complement component 6
chr23_+_17865554 2.58 ENSDART00000181009
ENSDART00000162822
nascent polypeptide-associated complex alpha subunit
chr2_+_38161318 2.55 ENSDART00000044264
matrix metallopeptidase 14b (membrane-inserted)
chr17_+_20605013 2.55 ENSDART00000156878
si:ch73-288o11.5
chr12_-_44307963 2.54 ENSDART00000161009
si:ch73-329n5.1
chr18_+_18455029 2.53 ENSDART00000165079
siah E3 ubiquitin protein ligase 1
chr23_+_38251864 2.52 ENSDART00000183498
ENSDART00000129593
zinc finger protein 217
chr2_-_45191319 2.50 ENSDART00000192272

chr9_-_33328948 2.50 ENSDART00000006948
ribosomal protein L8
chr16_-_32013913 2.50 ENSDART00000030282
ENSDART00000138701
glutathione S-transferase kappa 1
chr16_-_32208728 2.49 ENSDART00000023995
calcium homeostasis modulator family member 5, tandem duplicate 2
chr24_+_211217 2.49 ENSDART00000151925
ENSDART00000161636
si:dkey-225n22.4
chr21_+_5800306 2.48 ENSDART00000020603
cyclin G2
chr1_+_58282449 2.46 ENSDART00000131475
si:dkey-222h21.7
chr3_+_24634481 2.45 ENSDART00000163080
si:dkey-68o6.8

Network of associatons between targets according to the STRING database.

First level regulatory network of znf384l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.8 7.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
1.7 6.8 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.5 7.5 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
1.4 14.4 GO:0042989 sequestering of actin monomers(GO:0042989)
1.3 5.4 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
1.2 4.7 GO:0055107 Golgi to secretory granule transport(GO:0055107)
1.1 4.5 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
1.1 4.4 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
1.1 4.4 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
1.0 3.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
1.0 3.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.9 18.0 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.9 5.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.9 2.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) anterior lateral line neuromast hair cell development(GO:0035676)
0.9 2.7 GO:0032290 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.8 3.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.8 2.4 GO:0010265 SCF complex assembly(GO:0010265)
0.7 2.9 GO:1990697 protein depalmitoleylation(GO:1990697)
0.7 7.0 GO:0030104 water homeostasis(GO:0030104)
0.7 2.0 GO:0045730 respiratory burst(GO:0045730)
0.7 3.9 GO:0006004 fucose metabolic process(GO:0006004)
0.6 4.5 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.6 6.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.6 1.1 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.6 1.1 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.5 2.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.5 2.2 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.5 1.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.5 2.7 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.5 2.0 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.5 1.9 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.5 4.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.4 1.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 1.8 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.4 6.1 GO:0036065 fucosylation(GO:0036065)
0.4 6.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 2.7 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.4 0.8 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4 4.3 GO:0033198 response to ATP(GO:0033198)
0.4 2.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.4 1.8 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 10.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.3 5.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 7.3 GO:0015671 oxygen transport(GO:0015671)
0.3 2.1 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.3 3.2 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.3 1.0 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.3 3.8 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.3 1.3 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.3 2.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.3 4.7 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.3 1.2 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.3 5.5 GO:0042574 retinal metabolic process(GO:0042574)
0.3 1.4 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.3 3.4 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.3 2.6 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 6.0 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.3 3.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 1.6 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.3 5.2 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.3 1.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.3 1.8 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 4.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.3 7.1 GO:0051923 sulfation(GO:0051923)
0.3 2.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 1.2 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.2 1.2 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.2 2.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 9.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 2.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 1.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 3.8 GO:0046686 response to cadmium ion(GO:0046686)
0.2 4.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 3.1 GO:0090481 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.6 GO:0031179 peptide modification(GO:0031179)
0.2 3.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 1.7 GO:0045444 fat cell differentiation(GO:0045444)
0.2 2.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 3.5 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.2 0.6 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.2 4.6 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.2 2.1 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.5 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 1.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 1.7 GO:0001709 cell fate determination(GO:0001709)
0.2 1.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 4.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 0.8 GO:0071320 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 7.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.2 3.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.2 0.9 GO:0007141 male meiosis I(GO:0007141)
0.2 3.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 14.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 2.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 20.8 GO:0042742 defense response to bacterium(GO:0042742)
0.1 0.7 GO:0010447 response to acidic pH(GO:0010447)
0.1 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 3.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 5.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.2 GO:0034694 response to prostaglandin(GO:0034694) cellular response to prostaglandin stimulus(GO:0071379)
0.1 10.0 GO:0030048 actin filament-based movement(GO:0030048)
0.1 0.3 GO:0002698 negative regulation of immune effector process(GO:0002698)
0.1 3.1 GO:0006959 humoral immune response(GO:0006959)
0.1 1.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.3 GO:0014823 response to activity(GO:0014823)
0.1 5.8 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 3.2 GO:0030282 bone mineralization(GO:0030282)
0.1 1.3 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 3.6 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 3.2 GO:0009411 response to UV(GO:0009411)
0.1 1.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 4.2 GO:0071711 basement membrane organization(GO:0071711)
0.1 2.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 10.0 GO:0031101 fin regeneration(GO:0031101)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 3.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.0 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 1.2 GO:0046549 retinal cone cell development(GO:0046549)
0.1 3.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 9.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.9 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 2.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.0 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 7.5 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 1.9 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.1 1.2 GO:0010810 regulation of cell-substrate adhesion(GO:0010810) positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.3 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 2.9 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 2.9 GO:0046785 microtubule polymerization(GO:0046785)
0.1 1.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.1 1.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.7 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.1 2.2 GO:0060840 artery development(GO:0060840)
0.1 2.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 5.0 GO:0006612 protein targeting to membrane(GO:0006612)
0.1 5.0 GO:1901342 regulation of vasculature development(GO:1901342)
0.1 1.9 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 2.2 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.3 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 5.3 GO:0006821 chloride transport(GO:0006821)
0.1 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.8 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.1 1.5 GO:0042476 odontogenesis(GO:0042476)
0.1 0.3 GO:0043476 pigment accumulation(GO:0043476)
0.1 0.9 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.9 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 4.6 GO:0009617 response to bacterium(GO:0009617)
0.0 2.5 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 1.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 2.4 GO:0010842 retina layer formation(GO:0010842)
0.0 1.6 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 2.6 GO:0070997 neuron death(GO:0070997)
0.0 0.2 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 1.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.0 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.4 GO:0009204 nucleoside triphosphate catabolic process(GO:0009143) deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.0 0.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0032979 respiratory chain complex III assembly(GO:0017062) protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) mitochondrial respiratory chain complex III assembly(GO:0034551) protein insertion into mitochondrial membrane(GO:0051204) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 13.4 GO:0006955 immune response(GO:0006955)
0.0 0.6 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0085029 extracellular matrix assembly(GO:0085029)
0.0 3.6 GO:0001947 heart looping(GO:0001947)
0.0 3.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 2.4 GO:0051604 protein maturation(GO:0051604)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.7 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 3.3 GO:0072594 establishment of protein localization to organelle(GO:0072594)
0.0 1.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.0 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.9 GO:0001503 ossification(GO:0001503)
0.0 0.1 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 1.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.3 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 1.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.4 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0033334 fin morphogenesis(GO:0033334)
0.0 1.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.3 GO:0045597 positive regulation of cell differentiation(GO:0045597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.8 3.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.7 3.0 GO:0043073 germ cell nucleus(GO:0043073)
0.6 7.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 8.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 6.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 4.7 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 2.7 GO:0045095 keratin filament(GO:0045095)
0.2 5.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.2 GO:0031526 brush border membrane(GO:0031526)
0.2 2.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 4.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 1.0 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 9.6 GO:0008305 integrin complex(GO:0008305)
0.2 2.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 3.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 4.6 GO:0045178 basal part of cell(GO:0045178)
0.2 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 0.9 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 2.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.2 GO:0016234 inclusion body(GO:0016234)
0.2 15.1 GO:0005581 collagen trimer(GO:0005581)
0.2 16.0 GO:0030018 Z disc(GO:0030018)
0.2 2.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.7 GO:0048179 activin receptor complex(GO:0048179)
0.1 3.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 8.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 15.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 3.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 32.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.5 GO:0055087 Ski complex(GO:0055087)
0.1 6.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.1 GO:0005921 gap junction(GO:0005921)
0.1 10.5 GO:0005884 actin filament(GO:0005884)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 6.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 3.3 GO:0016605 PML body(GO:0016605)
0.1 1.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.2 GO:0044545 NSL complex(GO:0044545)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 7.7 GO:0005925 focal adhesion(GO:0005925)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 4.0 GO:0016592 mediator complex(GO:0016592)
0.1 3.8 GO:0005902 microvillus(GO:0005902)
0.1 5.6 GO:0005882 intermediate filament(GO:0005882)
0.1 5.7 GO:0005814 centriole(GO:0005814)
0.1 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.1 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 10.1 GO:0010008 endosome membrane(GO:0010008)
0.1 3.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 4.8 GO:0016459 myosin complex(GO:0016459)
0.0 13.3 GO:0005764 lysosome(GO:0005764)
0.0 2.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 1.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 4.2 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
0.0 4.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 28.0 GO:0005615 extracellular space(GO:0005615)
0.0 2.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 3.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.0 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
2.2 6.5 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.7 6.8 GO:0031708 endothelin B receptor binding(GO:0031708)
1.6 15.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.4 4.1 GO:0016748 succinyltransferase activity(GO:0016748)
1.3 3.9 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.9 8.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.9 4.4 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.7 2.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.7 3.7 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 14.4 GO:0003785 actin monomer binding(GO:0003785)
0.7 2.9 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.7 4.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.6 4.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6 7.3 GO:0031720 haptoglobin binding(GO:0031720)
0.6 2.3 GO:0005521 lamin binding(GO:0005521)
0.5 2.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.5 3.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 1.6 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.5 6.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.5 3.0 GO:0004960 thromboxane receptor activity(GO:0004960)
0.4 5.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 1.6 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.4 1.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 6.0 GO:2001069 glycogen binding(GO:2001069)
0.4 3.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 1.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 2.2 GO:0015616 DNA translocase activity(GO:0015616)
0.4 4.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4 4.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 4.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 1.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 2.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 2.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 2.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 1.2 GO:0070052 collagen V binding(GO:0070052)
0.3 1.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.3 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.3 1.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 2.6 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 3.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 3.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.2 5.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 4.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.2 GO:0060182 apelin receptor activity(GO:0060182)
0.2 3.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 2.8 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 4.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 3.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 5.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 10.0 GO:0000146 microfilament motor activity(GO:0000146)
0.2 0.5 GO:0000150 recombinase activity(GO:0000150)
0.2 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 4.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.6 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2 0.5 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 1.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 4.5 GO:0042805 actinin binding(GO:0042805)
0.2 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 1.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 6.9 GO:0019843 rRNA binding(GO:0019843)
0.2 3.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 5.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.2 3.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.8 GO:0008199 ferric iron binding(GO:0008199)
0.1 2.7 GO:0043236 laminin binding(GO:0043236)
0.1 4.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 5.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 4.5 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.1 1.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 8.1 GO:0005254 chloride channel activity(GO:0005254)
0.1 0.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 3.7 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.1 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 2.1 GO:0022829 wide pore channel activity(GO:0022829)
0.1 4.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 5.6 GO:0003823 antigen binding(GO:0003823)
0.1 0.3 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 2.0 GO:0005112 Notch binding(GO:0005112)
0.1 1.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 5.6 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 8.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 10.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 9.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.1 5.4 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 2.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 10.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 11.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0008252 nucleotidase activity(GO:0008252)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.0 4.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0002020 protease binding(GO:0002020)
0.0 2.8 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 11.4 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.6 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 2.6 GO:0005125 cytokine activity(GO:0005125)
0.0 9.8 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 3.2 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 5.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.4 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.0 GO:0030620 U2 snRNA binding(GO:0030620)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 PID ALK2 PATHWAY ALK2 signaling events
0.2 7.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 3.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 4.3 PID ENDOTHELIN PATHWAY Endothelins
0.2 2.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 3.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 1.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 2.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 3.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 2.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 4.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 9.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.2 PID RHOA PATHWAY RhoA signaling pathway
0.1 5.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 5.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 4.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 4.9 PID P53 REGULATION PATHWAY p53 pathway
0.1 11.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 2.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.5 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 4.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4 5.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 2.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 3.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 4.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 4.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 4.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 1.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 7.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 6.7 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.1 2.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 3.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 2.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 3.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 5.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 6.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 9.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.8 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 3.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.1 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 2.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA