Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for zbtb18+zbtb42

Z-value: 1.20

Motif logo

Transcription factors associated with zbtb18+zbtb42

Gene Symbol Gene ID Gene Info
ENSDARG00000028228 zinc finger and BTB domain containing 18
ENSDARG00000102761 zinc finger and BTB domain containing 42

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb18dr11_v1_chr13_+_11436130_114361300.151.4e-01Click!
zbtb42dr11_v1_chr17_-_1407593_14077250.018.9e-01Click!

Activity profile of zbtb18+zbtb42 motif

Sorted Z-values of zbtb18+zbtb42 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_27857051 11.58 ENSDART00000043462
ENSDART00000137861
activin A receptor like type 1
chr15_-_33834577 10.54 ENSDART00000163354
matrix metallopeptidase 13b
chr15_-_34567370 10.19 ENSDART00000099793
sclerostin domain containing 1a
chr10_-_15128771 9.98 ENSDART00000101261
secreted phosphoprotein 1
chr17_+_42274825 9.91 ENSDART00000020156
paired box 1a
chr18_-_6982499 9.54 ENSDART00000101525
si:dkey-266m15.6
chr1_+_40724140 9.44 ENSDART00000074839

chr25_+_35502552 8.68 ENSDART00000189612
ENSDART00000058443
fin bud initiation factor a
chr17_+_42274240 8.58 ENSDART00000134377
paired box 1a
chr10_+_8968203 7.75 ENSDART00000110443
ENSDART00000080772
follistatin b
chr16_-_26676685 7.74 ENSDART00000103431
epithelial splicing regulatory protein 1
chr19_-_35596207 7.43 ENSDART00000136811
collagen, type VIII, alpha 2
chr11_-_24681292 6.55 ENSDART00000089601
olfactomedin-like 3b
chr3_-_32596394 6.26 ENSDART00000103239
tetraspanin 4b
chr4_+_4232562 6.15 ENSDART00000177529
small lysine rich protein 1
chr5_+_30741730 5.74 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr9_-_9842149 5.65 ENSDART00000121456
follistatin-like 1b
chr6_+_23810529 5.63 ENSDART00000166921
glutamate-ammonia ligase (glutamine synthase) b
chr22_-_28653074 5.55 ENSDART00000154717
collagen, type VIII, alpha 1b
chr1_+_45351890 5.53 ENSDART00000145486
si:ch211-243a20.3
chr5_+_32924669 5.52 ENSDART00000085219
LIM domain only 4a
chr24_-_25166720 5.47 ENSDART00000141601
pleckstrin homology-like domain, family B, member 2b
chr3_-_54669185 5.24 ENSDART00000053106
sphingosine-1-phosphate receptor 2
chr20_+_16750177 5.21 ENSDART00000185357
calmodulin 1b
chr4_+_15944245 5.07 ENSDART00000134594
si:dkey-117n7.3
chr16_-_13595027 5.05 ENSDART00000060004
ntl-dependent gene 5
chr18_+_48423973 4.97 ENSDART00000184233
ENSDART00000147074
Fli-1 proto-oncogene, ETS transcription factor a
chr9_-_38587275 4.84 ENSDART00000077446
si:dkey-101k6.5
chr20_-_20932760 4.82 ENSDART00000152415
ENSDART00000039907
BTB (POZ) domain containing 6b
chr6_-_29195642 4.74 ENSDART00000078625
dermatopontin
chr1_+_58303892 4.69 ENSDART00000147678

chr20_+_23238833 4.69 ENSDART00000074167
OCIA domain containing 2
chr1_-_11973341 4.64 ENSDART00000159981
ENSDART00000066638
G protein-coupled receptor kinase 4
chr13_-_13294847 4.49 ENSDART00000125883
ENSDART00000013534
fibroblast growth factor receptor 3
chr22_-_26558166 4.37 ENSDART00000111125
GLIS family zinc finger 2a
chr25_+_753364 4.35 ENSDART00000183804
twinfilin actin binding protein 1
chr3_-_36839115 4.25 ENSDART00000154553
receptor (G protein-coupled) activity modifying protein 2
chr19_+_24882845 4.13 ENSDART00000010580
si:ch211-195b13.1
chr16_+_9609721 4.12 ENSDART00000047920
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr5_-_39474235 4.05 ENSDART00000171557
anthrax toxin receptor 2a
chr11_+_10548171 4.04 ENSDART00000191497
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr23_-_452365 3.92 ENSDART00000146776
tetraspanin 2b
chr15_-_25571865 3.88 ENSDART00000077836
matrix metallopeptidase 20b (enamelysin)
chr10_-_22803740 3.82 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr13_+_12045475 3.81 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
guanine nucleotide binding protein (G protein), gamma 2
chr12_-_28881638 3.77 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr19_+_1688727 3.71 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr8_-_9570511 3.71 ENSDART00000044000
plexin A3
chr7_+_56889879 3.71 ENSDART00000039810
myosin IXAa
chr19_+_47502581 3.65 ENSDART00000171526

chr20_-_13673566 3.64 ENSDART00000181641
si:ch211-122h15.4
chr21_+_22878834 3.61 ENSDART00000065562
PCF11 cleavage and polyadenylation factor subunit
chr9_+_22764235 3.54 ENSDART00000090875
tumor necrosis factor, alpha-induced protein 6
chr11_+_12719944 3.39 ENSDART00000054837
ENSDART00000144954
adaptor-related protein complex 1, sigma 2 subunit
chr16_-_50952266 3.35 ENSDART00000165408
si:dkeyp-97a10.3
chr18_-_46241775 3.32 ENSDART00000145999
ENSDART00000134244
ENSDART00000185021
ENSDART00000181855
periaxin
chr19_-_24267823 3.31 ENSDART00000132430
S100 calcium binding protein V2
chr24_+_2495197 3.25 ENSDART00000146887
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr11_+_12720171 3.23 ENSDART00000135761
ENSDART00000122812
adaptor-related protein complex 1, sigma 2 subunit
chr19_+_19489588 3.20 ENSDART00000166755
TLR4 interactor with leucine-rich repeats
chr13_+_25422009 3.16 ENSDART00000057686
calcium homeostasis modulator 2
chr4_-_17669881 3.08 ENSDART00000066997
DNA-damage regulated autophagy modulator 1
chr7_+_23577723 3.07 ENSDART00000049885
si:dkey-172j4.3
chr3_-_39363065 3.06 ENSDART00000155894
Rho GTPase activating protein 23a
chr17_+_29345606 3.05 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr25_-_31118923 2.98 ENSDART00000009126
ENSDART00000188286
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr2_-_32237916 2.95 ENSDART00000141418
family with sequence similarity 49, member Ba
chr3_-_53486169 2.95 ENSDART00000115243
heme-binding protein soul5
chr14_+_31865099 2.79 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr5_-_51998708 2.78 ENSDART00000097194
serine incorporator 5
chr23_-_21533949 2.73 ENSDART00000189010
regulator of chromosome condensation 2
chr2_+_36646451 2.72 ENSDART00000039174
kelch-like family member 6
chr21_+_22878991 2.67 ENSDART00000186399
PCF11 cleavage and polyadenylation factor subunit
chr10_+_7102461 2.65 ENSDART00000187539
pleckstrin and Sec7 domain containing 3, like
chr6_+_36821621 2.64 ENSDART00000104157
transmembrane protein 45a
chr21_-_18086114 2.61 ENSDART00000143987
vav 2 guanine nucleotide exchange factor
chr16_-_6849754 2.60 ENSDART00000149206
ENSDART00000149778
myelin basic protein b
chr24_-_26622423 2.57 ENSDART00000182044
TRAF2 and NCK interacting kinase b
chr16_+_2843428 2.52 ENSDART00000149485
C-type lectin domain family 3, member Ba
chr19_+_47311020 2.51 ENSDART00000138295
exostoses (multiple) 1c
chr19_+_32166702 2.49 ENSDART00000021798
fatty acid binding protein 11a
chr3_+_4213864 2.48 ENSDART00000059613
si:dkeyp-52c3.5
chr24_-_25166416 2.47 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr6_+_51824596 2.46 ENSDART00000149003
R-spondin 4
chr6_-_10809546 2.42 ENSDART00000151661
WAS/WASL interacting protein family, member 1b
chr16_-_17300030 2.41 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr7_-_2090594 2.33 ENSDART00000183166
si:cabz01007802.1
chr10_-_2971407 2.31 ENSDART00000132526
MARVEL domain containing 2a
chr8_-_29706882 2.30 ENSDART00000045909
perforin 1.5
chr6_-_1761256 2.30 ENSDART00000171313
origin recognition complex, subunit 4
chr22_-_5933844 2.30 ENSDART00000163370
ENSDART00000189331
si:rp71-36a1.2
chr22_-_6884981 2.26 ENSDART00000124219

chr19_+_22216778 2.21 ENSDART00000052521
nuclear factor of activated T cells 1
chr19_+_5315987 2.20 ENSDART00000145749
si:dkeyp-113d7.1
chr5_-_31904562 2.19 ENSDART00000140640
coronin, actin binding protein, 1Cb
chr13_+_25421531 2.15 ENSDART00000158093
calcium homeostasis modulator 2
chr3_-_3731563 2.15 ENSDART00000180978

chr7_-_19332293 2.11 ENSDART00000169668
ENSDART00000137575
ENSDART00000090406
dedicator of cytokinesis 11
chr11_+_34921492 2.11 ENSDART00000128070
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr7_+_34290051 2.10 ENSDART00000123498
fin bud initiation factor b
chr23_+_19977120 2.05 ENSDART00000089342
cilia and flagella associated protein 126
chr10_-_20537000 2.04 ENSDART00000064603
ENSDART00000135341
phospholipid phosphatase 5
chr11_+_30647545 2.02 ENSDART00000114792
expressed sequence EH507706
chr23_+_26079467 2.01 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr5_-_22082918 1.98 ENSDART00000020908
zinc finger, C4H2 domain containing
chr9_-_27410597 1.95 ENSDART00000135652
ENSDART00000042297
KDEL (Lys-Asp-Glu-Leu) containing 1
chr5_+_31480342 1.93 ENSDART00000098197
si:dkey-220k22.1
chr1_+_49878000 1.91 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr9_-_44983666 1.88 ENSDART00000149704
integrin, beta 2
chr20_+_20731633 1.88 ENSDART00000191952
ENSDART00000165224
protein phosphatase 1, regulatory subunit 13Bb
chr16_+_42830152 1.87 ENSDART00000159730
polymerase (RNA) III (DNA directed) polypeptide G like b
chr18_+_402048 1.86 ENSDART00000166345
glucose-6-phosphate isomerase b
chr24_-_1303935 1.85 ENSDART00000159212
ENSDART00000159267
ENSDART00000164904
neuropilin 1a
chr16_+_42829735 1.83 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr20_-_40451115 1.81 ENSDART00000075092
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr6_-_50704689 1.80 ENSDART00000074100
oxidative stress induced growth inhibitor 1
chr3_+_4047789 1.78 ENSDART00000148498
si:dkeyp-52c3.5
chr25_-_34632050 1.78 ENSDART00000170671
multiple EGF-like-domains 8
chr18_+_17959681 1.76 ENSDART00000142700
zinc finger protein 423
chr5_-_24124118 1.76 ENSDART00000051550
capping protein (actin filament), gelsolin-like a
chr12_-_7806007 1.75 ENSDART00000190359
ankyrin 3b
chr25_+_15841670 1.73 ENSDART00000049992
synaptotagmin IXb
chr2_-_42704863 1.66 ENSDART00000140159
myosin X
chr17_+_38255105 1.65 ENSDART00000005296
NK2 transcription factor related, locus 9 (Drosophila)
chr7_-_56606752 1.65 ENSDART00000138714
sulfotransferase family 5A, member 1
chr24_-_37877743 1.62 ENSDART00000105658
transmembrane protein 204
chr16_-_26232411 1.60 ENSDART00000139355
Rho guanine nucleotide exchange factor (GEF) 1b
chr20_-_38446891 1.57 ENSDART00000192013
inositol-trisphosphate 3-kinase B
chr2_+_31671545 1.56 ENSDART00000145446
atypical chemokine receptor 4a
chr7_-_41403022 1.55 ENSDART00000174285

chr17_-_19344999 1.52 ENSDART00000138315
goosecoid
chr24_+_41610068 1.48 ENSDART00000159507

chr14_-_24001825 1.42 ENSDART00000130704
interleukin 4
chr2_-_16449504 1.42 ENSDART00000144801
ATR serine/threonine kinase
chr6_+_1787160 1.42 ENSDART00000113505
myosin, light chain 9b, regulatory
chr21_+_42708621 1.41 ENSDART00000158392
si:ch1073-204b8.1
chr4_-_9609634 1.37 ENSDART00000067188
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr9_-_12424231 1.34 ENSDART00000188952
zgc:162707
chr10_+_40836378 1.34 ENSDART00000085792
tripartite motif containing 69
chr5_-_21888368 1.33 ENSDART00000020725
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr5_-_39805620 1.32 ENSDART00000137801
RasGEF domain family, member 1Ba
chr2_-_44746723 1.29 ENSDART00000041806
acyl-CoA synthetase medium chain family member 3
chr7_-_25895189 1.29 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr7_+_5494565 1.28 ENSDART00000135271
si:dkeyp-67a8.2
chr7_-_52153105 1.27 ENSDART00000174378

chr19_+_7627070 1.27 ENSDART00000151078
ENSDART00000131324
pygopus homolog 2 (Drosophila)
chr10_+_24445698 1.26 ENSDART00000146370
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr8_+_28358161 1.25 ENSDART00000062682
adiponectin receptor 1b
chr12_-_34716037 1.23 ENSDART00000152876
BAH domain and coiled-coil containing 1b
chr7_-_71837213 1.23 ENSDART00000168645
ENSDART00000160512
calcium channel, voltage-dependent, beta 2a
chr6_-_9707599 1.23 ENSDART00000039280
frizzled class receptor 7b
chr10_+_28587446 1.21 ENSDART00000030138
ENSDART00000137508
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr15_+_33989181 1.20 ENSDART00000169487
von Willebrand factor D and EGF domains
chr5_-_39805874 1.15 ENSDART00000176202
ENSDART00000191683
RasGEF domain family, member 1Ba
chr7_+_72003301 1.14 ENSDART00000012918
ENSDART00000182268
ENSDART00000185750
proteasome 26S subunit, non-ATPase 9
chr7_-_31794476 1.13 ENSDART00000142385
nucleosome assembly protein 1-like 4b
chr24_-_1303553 1.02 ENSDART00000190984
neuropilin 1a
chr20_+_405811 1.01 ENSDART00000149311
G protein-coupled receptor 63
chr19_-_1895832 1.01 ENSDART00000097530
ENSDART00000192739
ENSDART00000181795
si:ch211-149a19.3
chr10_-_24371312 0.98 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr5_-_14509137 0.97 ENSDART00000180742
si:ch211-244o22.2
chr20_-_14875308 0.97 ENSDART00000141290
dynamin 3a
chr22_+_25590391 0.97 ENSDART00000178133
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr3_+_13242690 0.94 ENSDART00000157097
Sad1 and UNC84 domain containing 1
chr13_-_33170733 0.94 ENSDART00000057382
fibulin 5
chr16_-_26437668 0.93 ENSDART00000142056
multiple EGF-like-domains 8
chr24_-_37877978 0.92 ENSDART00000128574
transmembrane protein 204
chr3_-_34586403 0.92 ENSDART00000151515
septin 9a
chr2_+_35732652 0.92 ENSDART00000052666
RAS protein activator like 2
chr19_+_20178978 0.91 ENSDART00000145115
ENSDART00000151175
transformer 2 alpha homolog
chr21_-_20342096 0.89 ENSDART00000065659
retinol binding protein 4, like
chr12_+_27055900 0.87 ENSDART00000153198
fibrosin
chr8_-_22558773 0.84 ENSDART00000074309
porcupine O-acyltransferase like
chr18_-_46369516 0.84 ENSDART00000018163
interferon regulatory factor 2 binding protein 1
chr20_+_23408970 0.80 ENSDART00000144261
furry homolog, like
chr23_-_19225709 0.75 ENSDART00000080099
O-acyl-ADP-ribose deacylase 1
chr7_-_6754012 0.75 ENSDART00000113658
zgc:55262
chr3_+_32129632 0.69 ENSDART00000174522
zgc:109934
chr16_+_8716800 0.68 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
chr19_+_27339848 0.64 ENSDART00000052355
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr8_+_7033049 0.63 ENSDART00000064172
ENSDART00000134440
glycerol-3-phosphate dehydrogenase 1a
chr5_-_19861766 0.63 ENSDART00000088904
glycolipid transfer protein a
chr10_-_11761927 0.61 ENSDART00000138748
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr21_-_5879897 0.60 ENSDART00000184034
ribosomal protein L35
chr5_-_24231139 0.57 ENSDART00000143492
SUMO1/sentrin/SMT3 specific peptidase 3a
chr20_+_14968031 0.55 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vesicle-associated membrane protein 4
chr13_-_36663358 0.55 ENSDART00000085319
son of sevenless homolog 2 (Drosophila)
chr15_-_16070731 0.55 ENSDART00000122099
dynein, light chain, LC8-type 2a
chr19_-_3482138 0.55 ENSDART00000168139
human immunodeficiency virus type I enhancer binding protein 1
chr1_-_21163532 0.54 ENSDART00000087670
ENSDART00000188893
si:dkey-253i9.4
chr22_+_17606863 0.54 ENSDART00000035670
polymerase (RNA) II (DNA directed) polypeptide E, b
chr16_+_26601364 0.53 ENSDART00000087537
erythrocyte membrane protein band 4.1 like 4B
chr1_-_9885320 0.51 ENSDART00000054843
ENSDART00000138630
zgc:56409
chr18_+_48953963 0.50 ENSDART00000158104
SH3KBP1 binding protein 1
chr20_+_6590220 0.50 ENSDART00000136567
tensin 3, tandem duplicate 2
chr17_-_8727699 0.49 ENSDART00000049236
ENSDART00000149505
ENSDART00000148619
ENSDART00000149668
ENSDART00000148827
C-terminal binding protein 2a
chr14_+_48964628 0.49 ENSDART00000105427
macrophage migration inhibitory factor
chr9_-_12424791 0.48 ENSDART00000135447
ENSDART00000088199
zgc:162707
chr4_+_77973876 0.44 ENSDART00000057423
telomeric repeat binding factor a
chr2_-_37043540 0.44 ENSDART00000131834
guanine nucleotide binding protein (G protein), gamma 7

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb18+zbtb42

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.6 GO:0034405 response to fluid shear stress(GO:0034405)
1.7 5.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) anterior lateral line neuromast hair cell development(GO:0035676)
1.2 4.6 GO:0044003 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.9 6.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.8 5.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.8 3.9 GO:0097186 amelogenesis(GO:0097186)
0.7 3.7 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.7 7.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.7 3.4 GO:1901207 regulation of heart looping(GO:1901207)
0.6 4.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.6 2.9 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.5 1.4 GO:0002369 T cell cytokine production(GO:0002369)
0.5 3.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.4 4.0 GO:1901998 toxin transport(GO:1901998)
0.4 2.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.4 1.9 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.3 10.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 1.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.3 1.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 0.8 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 5.6 GO:0060034 notochord cell differentiation(GO:0060034)
0.2 2.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 3.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 10.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.2 1.8 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.2 0.6 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 2.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.8 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 1.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 4.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 3.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.5 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 3.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 10.0 GO:0060348 bone development(GO:0060348)
0.1 2.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 4.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 4.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.4 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.1 1.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 2.9 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.9 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.0 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 1.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.7 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 2.0 GO:0048665 neuron fate specification(GO:0048665)
0.1 5.5 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.1 2.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 0.5 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 2.3 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.7 GO:0060972 left/right pattern formation(GO:0060972)
0.1 2.6 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 1.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 2.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.7 GO:0051923 sulfation(GO:0051923)
0.1 13.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 1.8 GO:0051014 actin filament severing(GO:0051014)
0.1 2.5 GO:0030282 bone mineralization(GO:0030282)
0.1 4.2 GO:0030048 actin filament-based movement(GO:0030048)
0.1 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 6.6 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 2.7 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 5.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 2.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 2.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 3.1 GO:0042742 defense response to bacterium(GO:0042742)
0.0 2.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 2.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.2 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.9 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.6 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 8.2 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 3.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 1.5 GO:0021782 glial cell development(GO:0021782)
0.0 2.3 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 2.0 GO:0044782 cilium organization(GO:0044782)
0.0 4.0 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 1.3 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 3.2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.6 GO:0070724 BMP receptor complex(GO:0070724)
0.6 2.3 GO:0061689 tricellular tight junction(GO:0061689)
0.4 4.0 GO:0070938 contractile ring(GO:0070938)
0.3 2.0 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.3 6.8 GO:0045180 basal cortex(GO:0045180)
0.3 6.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.3 4.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 1.3 GO:0016589 NURF complex(GO:0016589)
0.2 4.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 2.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 3.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.1 2.6 GO:0043209 myelin sheath(GO:0043209)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 25.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 3.7 GO:0030426 growth cone(GO:0030426)
0.1 6.1 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 2.7 GO:0030496 midbody(GO:0030496)
0.1 0.4 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.0 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.9 GO:0008305 integrin complex(GO:0008305)
0.0 65.4 GO:0005576 extracellular region(GO:0005576)
0.0 0.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.9 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.0 6.5 GO:0009986 cell surface(GO:0009986)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 1.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 4.4 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.3 10.2 GO:0036122 BMP binding(GO:0036122)
1.0 11.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.8 5.6 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7 5.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.6 2.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.5 4.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.4 7.8 GO:0048185 activin binding(GO:0048185)
0.4 1.2 GO:0047690 aspartyltransferase activity(GO:0047690)
0.3 4.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.3 1.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 4.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 6.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 2.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 4.2 GO:0015026 coreceptor activity(GO:0015026)
0.2 4.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.3 GO:0034632 retinol transporter activity(GO:0034632)
0.2 2.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 4.0 GO:0031267 small GTPase binding(GO:0031267)
0.2 3.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 3.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.6 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 3.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 16.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.9 GO:0002039 p53 binding(GO:0002039)
0.1 3.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.6 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 11.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.3 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 2.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 7.5 GO:0008201 heparin binding(GO:0008201)
0.1 0.2 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 3.0 GO:0019003 GDP binding(GO:0019003)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 1.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 11.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 4.9 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 5.0 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.8 GO:0020037 heme binding(GO:0020037)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 11.6 PID ALK1 PATHWAY ALK1 signaling events
0.5 5.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.4 3.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 1.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 3.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 2.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 7.4 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 4.5 PID FGF PATHWAY FGF signaling pathway
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 12.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.6 6.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5 3.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 3.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 6.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 4.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 7.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 1.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 11.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 4.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 4.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease