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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for yy1a+yy1b

Z-value: 3.37

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Transcription factors associated with yy1a+yy1b

Gene Symbol Gene ID Gene Info
ENSDARG00000027978 YY1 transcription factor b
ENSDARG00000042796 YY1 transcription factor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
yy1bdr11_v1_chr20_-_54435287_544352870.742.0e-17Click!
yy1adr11_v1_chr17_-_30863252_308632520.511.9e-07Click!

Activity profile of yy1a+yy1b motif

Sorted Z-values of yy1a+yy1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_4915118 38.49 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr24_-_6158933 37.91 ENSDART00000021609
glutamate decarboxylase 2
chr5_-_29643381 34.34 ENSDART00000034849
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr21_+_11468934 32.22 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr10_-_31782616 31.22 ENSDART00000128839
fasciculation and elongation protein zeta 1 (zygin I)
chr15_+_28685892 29.65 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr7_+_32722227 28.32 ENSDART00000126565
si:ch211-150g13.3
chr4_-_7212875 26.89 ENSDART00000161297
leucine rich repeat neuronal 3b
chr12_+_9817440 25.57 ENSDART00000137081
ENSDART00000123712
RUN domain containing 3Ab
chr12_-_14922955 25.19 ENSDART00000002078
neurogenic differentiation 2
chr12_+_27285994 25.05 ENSDART00000087204
dual specificity phosphatase 3a
chr23_+_36771593 24.73 ENSDART00000078240
membrane-associated ring finger (C3HC4) 9
chr15_-_33896159 24.65 ENSDART00000159791
myelin associated glycoprotein
chr5_+_32162684 24.61 ENSDART00000134472
TAO kinase 3b
chr20_+_54738210 24.56 ENSDART00000151399
p21 protein (Cdc42/Rac)-activated kinase 7
chr22_+_17205608 24.50 ENSDART00000181267
RAB3B, member RAS oncogene family
chr19_-_7450796 23.55 ENSDART00000104750
MLLT11, transcription factor 7 cofactor
chr13_-_30027730 23.52 ENSDART00000044009
stearoyl-CoA desaturase b
chr18_-_1228688 23.48 ENSDART00000064403
neuroplastin b
chr16_-_16182319 23.40 ENSDART00000103815
stathmin 2a
chr15_+_17321218 22.69 ENSDART00000143796
clathrin, heavy chain b (Hc)
chr4_+_19535946 22.62 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
leucine rich repeat containing 4.1
chr1_-_14234076 22.52 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr19_-_10394931 22.47 ENSDART00000191549
zgc:194578
chr2_+_5621529 22.39 ENSDART00000144187
fibroblast growth factor 12a
chr17_-_26911852 22.35 ENSDART00000045842
regulator of calcineurin 3
chr5_+_42912966 22.30 ENSDART00000039973
RUN and FYVE domain containing 3
chr18_-_36135799 21.63 ENSDART00000059344
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr17_-_43466317 21.28 ENSDART00000155313
heat shock protein 4 like
chr8_+_31941650 21.08 ENSDART00000138217
5-hydroxytryptamine (serotonin) receptor 1A a
chr3_+_50310684 20.60 ENSDART00000112152
growth arrest-specific 7a
chr18_+_28102620 20.55 ENSDART00000132342
KIAA1549-like b
chr20_-_34801181 20.54 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr8_+_7359294 20.53 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr9_-_24413008 20.43 ENSDART00000135897
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr4_+_21129752 20.36 ENSDART00000169764
synaptotagmin Ia
chr20_+_34913069 20.22 ENSDART00000007584
synaptosomal-associated protein, 25a
chr5_+_54685175 20.15 ENSDART00000115016
pro-melanin-concentrating hormone, like
chr1_-_14233815 20.05 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr2_+_50862527 19.80 ENSDART00000169800
ENSDART00000158847
ENSDART00000160900
adenylate cyclase activating polypeptide 1a (pituitary) receptor type I
chr14_+_35691889 19.57 ENSDART00000074685
glycine receptor, beta b
chr17_-_15640467 19.50 ENSDART00000014210
fucosyltransferase 9a
chr9_+_31282161 19.49 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr12_+_18556929 19.26 ENSDART00000191277

chr2_-_24462277 19.00 ENSDART00000033922
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr13_+_15838151 18.77 ENSDART00000008987
kinesin light chain 1a
chr7_-_52842007 18.77 ENSDART00000182710
microtubule-associated protein 1Aa
chr9_+_29581662 18.70 ENSDART00000187283
mcf.2 cell line derived transforming sequence-like b
chr16_-_9383629 18.65 ENSDART00000084264
ENSDART00000166958
adenylate cyclase 2a
chr16_+_34528409 18.65 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr21_-_43952958 18.62 ENSDART00000039571
calcium/calmodulin-dependent protein kinase II alpha
chr23_-_30431333 18.13 ENSDART00000146633
calmodulin binding transcription activator 1a
chr5_-_26093945 18.13 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr7_+_40228422 18.04 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr9_-_31278048 17.98 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr7_+_529522 17.94 ENSDART00000190811
neurexin 2b
chr25_+_7670683 17.88 ENSDART00000040275
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr6_-_11792152 17.86 ENSDART00000183403
membrane-associated ring finger (C3HC4) 7
chr19_-_10395683 17.69 ENSDART00000109488
zgc:194578
chr1_-_22861348 17.66 ENSDART00000139412
si:dkey-92j12.6
chr16_-_29452039 17.64 ENSDART00000148960
si:ch211-113g11.6
chr4_+_23223881 17.56 ENSDART00000133056
ENSDART00000089126
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr16_-_27628994 17.44 ENSDART00000157407
NAC alpha domain containing
chr1_-_29045426 17.36 ENSDART00000019770
glycoprotein M6Ba
chr23_-_46217134 17.26 ENSDART00000189477
ENSDART00000168352

chr24_-_21921262 16.85 ENSDART00000186061
ENSDART00000187846
transgelin 3b
chr4_+_8797197 16.83 ENSDART00000158671
sulfotransferase family 4A, member 1
chr10_+_25219728 16.74 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr12_+_21525496 16.56 ENSDART00000152974
carbonic anhydrase Xa
chr5_+_63668735 16.55 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr17_-_15528597 16.50 ENSDART00000150232
FYN proto-oncogene, Src family tyrosine kinase a
chr9_-_44295071 16.31 ENSDART00000011837
neuronal differentiation 1
chr22_+_11535131 16.21 ENSDART00000113930
neuropeptide B
chr10_+_22012389 16.20 ENSDART00000035188
Kv channel interacting protein 1 b
chr21_-_42007482 16.18 ENSDART00000075740
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr16_-_29334672 16.17 ENSDART00000162835
brevican
chr25_-_19443421 16.09 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr5_-_32323136 16.06 ENSDART00000110804
heat shock protein, alpha-crystallin-related, b15
chr13_-_33398735 15.94 ENSDART00000182601
ENSDART00000103628
BTB (POZ) domain containing 6a
chr18_+_41495841 15.91 ENSDART00000098671
si:ch211-203b8.6
chr18_+_22793743 15.89 ENSDART00000150106
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr16_-_13662514 15.84 ENSDART00000146348
shisa family member 7a
chr14_-_51855047 15.83 ENSDART00000088912
complexin 1
chr6_-_13187168 15.82 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr7_-_35710263 15.78 ENSDART00000043857
iroquois homeobox 5a
chr17_-_4318393 15.76 ENSDART00000167995
ENSDART00000153824
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr24_+_32472155 15.73 ENSDART00000098859
neuronal differentiation 6a
chr20_-_30035326 15.72 ENSDART00000141068
SRY (sex determining region Y)-box 11b
chr5_+_64739762 15.52 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfactomedin 1a
chr18_+_24922125 15.16 ENSDART00000180385
repulsive guidance molecule family member a
chr25_-_13381854 15.09 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr8_-_17064243 15.03 ENSDART00000185313
RAB3C, member RAS oncogene family
chr8_-_51404806 15.03 ENSDART00000060625
leucine-rich repeat LGI family, member 3
chr23_+_28374458 14.96 ENSDART00000140058
ENSDART00000144240
zgc:153867
chr13_-_35051897 14.93 ENSDART00000129559
BTB (POZ) domain containing 3b
chr25_+_15354095 14.90 ENSDART00000090397
KIAA1549-like a
chr17_-_36936649 14.85 ENSDART00000145236
dihydropyrimidinase-like 5a
chr7_+_38716048 14.77 ENSDART00000024590
synaptotagmin XIII
chr7_+_50109239 14.74 ENSDART00000021605
si:dkey-6l15.1
chr8_-_14050758 14.40 ENSDART00000133922
ATPase plasma membrane Ca2+ transporting 3a
chr13_+_16522608 14.34 ENSDART00000182838
ENSDART00000143200
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr12_-_41618844 14.22 ENSDART00000160054
dihydropyrimidinase-like 4
chr9_+_42066030 14.19 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr16_-_16590780 14.09 ENSDART00000059841
si:ch211-257p13.3
chr18_-_21218851 14.00 ENSDART00000060160
calbindin 2a
chr3_+_29714775 13.99 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr6_-_42111937 13.95 ENSDART00000181772
glutamate receptor, metabotropic 2a
chr12_+_13405445 13.93 ENSDART00000089042
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr23_+_2778813 13.91 ENSDART00000142621
DNA topoisomerase I
chr12_-_3453589 13.89 ENSDART00000175918

chr13_-_27660955 13.86 ENSDART00000188651
ENSDART00000134494
regulating synaptic membrane exocytosis 1a
chr8_-_34052019 13.79 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr8_-_9118958 13.75 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr6_-_51101834 13.73 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr25_-_31863374 13.72 ENSDART00000028338
secretory carrier membrane protein 5a
chr17_-_15382704 13.65 ENSDART00000005313
zgc:85722
chr13_+_24287093 13.60 ENSDART00000058628
centriole, cilia and spindle-associated protein b
chr18_+_22793465 13.55 ENSDART00000149685
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr6_+_41555247 13.48 ENSDART00000084834
SLIT-ROBO Rho GTPase activating protein 3
chr6_-_13408680 13.47 ENSDART00000151566
formin-like 2b
chr10_-_22845485 13.46 ENSDART00000079454
vesicle-associated membrane protein 2
chr25_-_5740334 13.36 ENSDART00000169622
ENSDART00000168720

chr17_-_36936856 13.31 ENSDART00000010274
ENSDART00000188887
dihydropyrimidinase-like 5a
chr1_+_45323400 13.20 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr19_+_16032383 13.20 ENSDART00000046530
RAB42, member RAS oncogene family a
chr3_-_24980067 13.12 ENSDART00000048871
desumoylating isopeptidase 1a
chr25_+_14017609 13.06 ENSDART00000129105
ENSDART00000125733
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr5_+_15667874 13.06 ENSDART00000127015
serine/arginine repetitive matrix 4
chr11_+_30817943 13.05 ENSDART00000150130
ENSDART00000159997
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr9_-_12034444 13.03 ENSDART00000038651
zinc finger protein 804A
chr6_+_55174744 12.98 ENSDART00000023562
synaptotagmin 2
chr24_+_4977862 12.95 ENSDART00000114537
zic family member 4
chr9_+_40939336 12.89 ENSDART00000100386
myostatin b
chr14_+_31529958 12.83 ENSDART00000053026
family with sequence similarity 122B
chr12_+_42436328 12.82 ENSDART00000167324
early B cell factor 3a
chr9_-_7444753 12.74 ENSDART00000146424
bridging integrator 1a
chr13_+_13693722 12.64 ENSDART00000110509
si:ch211-194c3.5
chr17_-_48915427 12.63 ENSDART00000054781
galectin 8b
chr23_+_4299887 12.60 ENSDART00000132604
l(3)mbt-like 1a (Drosophila)
chr2_+_38151308 12.50 ENSDART00000180948
spalt-like transcription factor 2
chr16_+_14029283 12.48 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr25_+_7229046 12.47 ENSDART00000149965
ENSDART00000041820
leucine rich repeat and Ig domain containing 1a
chr20_-_39271844 12.45 ENSDART00000192708
clusterin
chr18_+_24921587 12.39 ENSDART00000191345
repulsive guidance molecule family member a
chr10_-_24371312 12.34 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr14_-_32744464 12.30 ENSDART00000075617
SRY (sex determining region Y)-box 3
chr3_-_13146631 12.29 ENSDART00000172460
protein kinase, cAMP-dependent, regulatory, type I, beta
chr17_-_26926577 12.28 ENSDART00000050202
regulator of calcineurin 3
chr19_+_6938289 12.27 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr12_+_18681477 12.27 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr18_-_14734678 12.18 ENSDART00000142462
teashirt zinc finger homeobox 3a
chr25_+_19999623 12.18 ENSDART00000026401
zgc:194665
chr6_+_39836474 12.16 ENSDART00000112637
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr5_-_26284276 12.14 ENSDART00000148608
ARVCF, delta catenin family member b
chr12_-_26383242 12.13 ENSDART00000152941
ubiquitin specific peptidase 54b
chr9_+_2393764 12.12 ENSDART00000172624
chimerin 1
chr5_+_36415978 12.06 ENSDART00000084464
family with sequence similarity 155, member B
chr12_+_25640480 12.05 ENSDART00000105608
protein kinase C, epsilon a
chr23_-_26077038 12.05 ENSDART00000126299
GDP dissociation inhibitor 1
chr16_-_13789908 12.01 ENSDART00000138540
tweety family member 1
chr16_-_16590489 12.00 ENSDART00000190021
si:ch211-257p13.3
chr18_-_35736591 11.98 ENSDART00000036015
ryanodine receptor 1b (skeletal)
chr14_-_2189889 11.98 ENSDART00000181557
ENSDART00000106707
protocadherin 2 alpha b 9
protocadherin 2 alpha b 11
chr16_-_8927425 11.96 ENSDART00000000382
trio Rho guanine nucleotide exchange factor b
chr18_-_38088099 11.95 ENSDART00000146120
leucine zipper protein 2
chr19_+_10396042 11.93 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr6_-_24358732 11.91 ENSDART00000159595
epoxide hydrolase 4
chr9_+_21535885 11.91 ENSDART00000141408
Rho guanine nucleotide exchange factor (GEF) 7a
chr3_+_32403758 11.90 ENSDART00000156982
si:ch211-195b15.8
chr16_-_23379464 11.90 ENSDART00000045891
tripartite motif containing 46a
chr22_-_38607504 11.86 ENSDART00000164609
si:ch211-126j24.1
chr5_-_37875636 11.86 ENSDART00000184674
Rho GTPase activating protein 35b
chr9_-_7421135 11.82 ENSDART00000144600
bridging integrator 1a
chr2_-_31634978 11.80 ENSDART00000135668
si:ch211-106h4.9
chr9_+_34425736 11.80 ENSDART00000135147
si:ch211-218d20.15
chr17_-_18888959 11.78 ENSDART00000080029
adenylate kinase 7b
chr23_+_22200467 11.78 ENSDART00000025414
solute carrier family 2 (facilitated glucose transporter), member 1a
chr24_+_34606966 11.77 ENSDART00000105477
leucine rich repeat transmembrane neuronal 2
chr6_-_957830 11.76 ENSDART00000090019
ENSDART00000184286
zinc finger E-box binding homeobox 2b
chr22_+_12366516 11.75 ENSDART00000157802
R3H domain containing 1
chr1_-_26294995 11.75 ENSDART00000168594
CXXC finger 4
chr5_-_13685047 11.70 ENSDART00000018351
zgc:65851
chr1_-_23557877 11.63 ENSDART00000145942
family with sequence similarity 184, member B
chr18_+_21408794 11.63 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr18_+_31410652 11.61 ENSDART00000098504
differentially expressed in FDCP 8 homolog (mouse)
chr4_+_5506952 11.59 ENSDART00000032857
ENSDART00000160222
mitogen-activated protein kinase 11
chr2_-_44720551 11.58 ENSDART00000146380
MAP6 domain containing 1
chr4_-_11163112 11.46 ENSDART00000188854
protein arginine methyltransferase 8b
chr10_-_7974155 11.45 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr7_-_52963493 11.44 ENSDART00000052029
cocaine- and amphetamine-regulated transcript 3
chr7_+_22823889 11.42 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
phosphorylase, glycogen, muscle b
chr3_-_22191132 11.41 ENSDART00000154226
ENSDART00000155528
ENSDART00000155190
microtubule-associated protein tau b
chr17_+_9310259 11.40 ENSDART00000186158
ENSDART00000190329
neuronal PAS domain protein 3
chr18_+_26337869 11.39 ENSDART00000109257
si:ch211-234p18.3
chr19_+_9459050 11.36 ENSDART00000186419
si:ch211-288g17.3
chr12_-_35787801 11.35 ENSDART00000171682
apoptosis-associated tyrosine kinase b
chr21_+_26389391 11.31 ENSDART00000077197
thymosin, beta
chr21_-_42007213 11.31 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr9_+_29643036 11.30 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr13_+_38302665 11.29 ENSDART00000145777
adhesion G protein-coupled receptor B3

Network of associatons between targets according to the STRING database.

First level regulatory network of yy1a+yy1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 37.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
6.5 6.5 GO:1905067 negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
6.3 25.2 GO:0060074 synapse maturation(GO:0060074)
5.9 23.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
5.8 17.4 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
5.7 17.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
5.5 27.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
5.5 27.5 GO:0070208 protein heterotrimerization(GO:0070208)
4.9 34.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
4.9 88.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
4.7 23.5 GO:0090199 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
4.1 12.3 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
3.9 15.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
3.8 11.4 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
3.7 11.1 GO:0035902 response to immobilization stress(GO:0035902)
3.5 28.0 GO:0008343 adult feeding behavior(GO:0008343)
3.5 14.0 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
3.4 23.6 GO:0021534 cell proliferation in hindbrain(GO:0021534)
3.3 9.9 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
3.2 12.9 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
3.1 9.4 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
3.0 12.1 GO:0021557 oculomotor nerve development(GO:0021557)
3.0 9.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
2.8 8.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
2.8 11.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
2.7 13.6 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
2.7 10.8 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
2.7 8.0 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.6 15.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
2.5 10.0 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
2.5 2.5 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
2.3 20.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
2.3 9.1 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
2.3 18.2 GO:0034334 adherens junction maintenance(GO:0034334)
2.3 11.3 GO:0016322 neuron remodeling(GO:0016322)
2.2 6.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.2 8.9 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
2.2 24.3 GO:0050795 regulation of behavior(GO:0050795)
2.2 6.6 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
2.2 6.6 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
2.2 10.9 GO:0021855 axon target recognition(GO:0007412) hypothalamus cell migration(GO:0021855)
2.2 24.0 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
2.1 12.9 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
2.1 12.7 GO:0003232 bulbus arteriosus development(GO:0003232)
2.1 33.8 GO:0007631 feeding behavior(GO:0007631)
2.1 6.3 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
2.1 29.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
2.0 8.1 GO:0035095 behavioral response to nicotine(GO:0035095)
2.0 9.9 GO:0031053 primary miRNA processing(GO:0031053)
1.9 5.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
1.9 9.6 GO:0061072 iris morphogenesis(GO:0061072)
1.9 19.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.9 13.1 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
1.8 23.7 GO:0010996 response to auditory stimulus(GO:0010996)
1.8 41.6 GO:0042551 neuron maturation(GO:0042551)
1.8 7.0 GO:1900120 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
1.8 15.8 GO:0072498 embryonic skeletal joint development(GO:0072498)
1.7 15.5 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
1.7 5.2 GO:0032263 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
1.7 6.7 GO:0008090 retrograde axonal transport(GO:0008090)
1.7 6.7 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
1.7 11.6 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
1.6 4.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.6 14.7 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
1.6 4.9 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.6 11.3 GO:0046323 glucose import(GO:0046323)
1.6 9.6 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
1.6 17.5 GO:0046548 retinal rod cell development(GO:0046548)
1.6 72.5 GO:0007019 microtubule depolymerization(GO:0007019)
1.6 34.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.6 7.8 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.5 9.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
1.5 14.6 GO:0003310 pancreatic A cell differentiation(GO:0003310)
1.4 7.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
1.4 4.2 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
1.4 5.5 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
1.4 23.2 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
1.3 4.0 GO:0072020 proximal straight tubule development(GO:0072020)
1.3 6.6 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
1.3 6.6 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
1.3 5.3 GO:0099563 modification of synaptic structure(GO:0099563)
1.3 3.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.3 5.2 GO:0051012 microtubule sliding(GO:0051012)
1.3 19.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
1.3 23.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
1.3 6.4 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
1.3 6.3 GO:0030326 embryonic limb morphogenesis(GO:0030326)
1.3 12.6 GO:0032288 myelin assembly(GO:0032288)
1.3 12.5 GO:0021576 hindbrain formation(GO:0021576)
1.3 2.5 GO:0030811 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
1.3 38.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.2 22.5 GO:0016082 synaptic vesicle priming(GO:0016082)
1.2 2.5 GO:0034204 lipid translocation(GO:0034204)
1.2 8.6 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
1.2 3.7 GO:0035973 aggrephagy(GO:0035973)
1.2 19.5 GO:0036065 fucosylation(GO:0036065)
1.2 9.7 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.2 3.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.2 4.7 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
1.2 3.5 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
1.2 3.5 GO:0042766 nucleosome mobilization(GO:0042766)
1.2 25.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.2 5.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
1.2 6.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.2 10.4 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
1.1 31.8 GO:0070831 basement membrane assembly(GO:0070831)
1.1 18.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
1.1 17.9 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
1.1 3.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
1.1 7.8 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
1.1 24.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
1.1 15.4 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
1.1 6.6 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
1.1 10.9 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
1.1 38.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.1 4.3 GO:0016117 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
1.1 4.3 GO:0061010 gall bladder development(GO:0061010)
1.1 5.4 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
1.1 7.6 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.1 11.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
1.1 17.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.1 41.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
1.1 3.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
1.1 4.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
1.1 4.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.0 5.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529)
1.0 13.5 GO:0035493 SNARE complex assembly(GO:0035493)
1.0 4.1 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.0 39.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
1.0 3.1 GO:0070914 UV-damage excision repair(GO:0070914)
1.0 4.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
1.0 6.0 GO:0070650 actin filament bundle distribution(GO:0070650)
1.0 7.0 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
1.0 7.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
1.0 5.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
1.0 2.0 GO:0001919 regulation of receptor recycling(GO:0001919)
1.0 2.0 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
1.0 9.7 GO:0003315 heart rudiment formation(GO:0003315)
1.0 3.9 GO:0061469 type B pancreatic cell proliferation(GO:0044342) eye pigmentation(GO:0048069) regulation of type B pancreatic cell proliferation(GO:0061469)
1.0 7.7 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
1.0 6.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.9 2.7 GO:0071514 genetic imprinting(GO:0071514)
0.9 12.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.9 4.5 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.9 6.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.9 8.9 GO:0007340 acrosome reaction(GO:0007340)
0.9 4.4 GO:1903018 regulation of glycoprotein biosynthetic process(GO:0010559) regulation of protein glycosylation(GO:0060049) regulation of glycoprotein metabolic process(GO:1903018)
0.9 15.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.9 31.4 GO:0036269 swimming behavior(GO:0036269)
0.9 3.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.9 2.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.9 2.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.9 12.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.8 6.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.8 21.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.8 4.2 GO:0050932 regulation of pigment cell differentiation(GO:0050932)
0.8 5.9 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.8 10.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.8 5.8 GO:0070206 protein trimerization(GO:0070206)
0.8 5.8 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.8 5.0 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.8 6.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.8 3.2 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.8 42.9 GO:0048813 dendrite morphogenesis(GO:0048813)
0.8 3.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.8 23.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.8 19.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.8 12.7 GO:0006265 DNA topological change(GO:0006265)
0.8 8.6 GO:0034605 cellular response to heat(GO:0034605)
0.8 14.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.8 3.1 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.8 2.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.8 4.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.8 2.3 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.8 7.6 GO:0050975 sensory perception of touch(GO:0050975)
0.8 4.6 GO:1902914 regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.8 4.6 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.8 4.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.8 9.8 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.7 7.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.7 2.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.7 8.9 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.7 2.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.7 2.2 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.7 2.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.7 66.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.7 2.2 GO:0006089 lactate metabolic process(GO:0006089)
0.7 14.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.7 17.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.7 1.4 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.7 2.8 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.7 10.6 GO:0008354 germ cell migration(GO:0008354)
0.7 9.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.7 3.5 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.7 6.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.7 4.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.7 11.6 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.7 6.1 GO:0021754 facial nucleus development(GO:0021754)
0.7 18.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.7 5.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.7 15.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.7 0.7 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.7 2.6 GO:0042478 regulation of eye photoreceptor cell development(GO:0042478)
0.7 6.5 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.7 15.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.7 12.4 GO:1903307 positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.7 2.0 GO:0002188 translation reinitiation(GO:0002188)
0.6 1.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.6 3.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.6 4.5 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.6 6.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.6 4.5 GO:1902259 regulation of potassium ion transmembrane transporter activity(GO:1901016) regulation of delayed rectifier potassium channel activity(GO:1902259)
0.6 8.3 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.6 1.3 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.6 1.9 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.6 6.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 8.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.6 1.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.6 13.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.6 6.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.6 8.6 GO:0007413 axonal fasciculation(GO:0007413)
0.6 22.7 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.6 3.6 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.6 6.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.6 3.0 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.6 6.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.6 1.8 GO:0010737 protein kinase A signaling(GO:0010737)
0.6 33.7 GO:0030641 regulation of cellular pH(GO:0030641)
0.6 33.0 GO:0070509 calcium ion import(GO:0070509)
0.6 6.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.6 2.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.6 8.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.6 4.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.6 3.4 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.6 15.7 GO:0051923 sulfation(GO:0051923)
0.6 5.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.6 13.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.6 3.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.6 1.1 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.6 2.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.5 3.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.5 38.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.5 1.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 12.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.5 2.6 GO:0051701 interaction with host(GO:0051701)
0.5 1.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.5 1.6 GO:0070126 mitochondrial translational termination(GO:0070126)
0.5 11.2 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.5 1.5 GO:0009750 response to fructose(GO:0009750)
0.5 3.0 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.5 2.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5 12.5 GO:0031103 axon regeneration(GO:0031103)
0.5 5.4 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 11.3 GO:0043266 regulation of potassium ion transport(GO:0043266) regulation of potassium ion transmembrane transport(GO:1901379)
0.5 2.9 GO:1901490 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.5 10.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.5 4.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.5 2.8 GO:0021594 rhombomere formation(GO:0021594) rhombomere boundary formation(GO:0021654)
0.5 1.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.5 4.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.5 6.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.5 4.7 GO:0035108 limb morphogenesis(GO:0035108)
0.5 7.0 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.5 2.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.5 8.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.5 12.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.5 3.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.4 3.6 GO:0032196 transposition(GO:0032196)
0.4 22.2 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.4 10.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 0.9 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.4 6.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.4 1.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 4.7 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 12.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.4 10.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.4 9.9 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.4 4.8 GO:0050890 cognition(GO:0050890)
0.4 2.0 GO:0023041 neuronal signal transduction(GO:0023041)
0.4 1.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.4 2.0 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.4 1.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.4 16.6 GO:1901214 regulation of neuron death(GO:1901214)
0.4 6.3 GO:0042073 intraciliary transport(GO:0042073)
0.4 5.1 GO:0032418 lysosome localization(GO:0032418)
0.4 3.9 GO:0097324 melanocyte migration(GO:0097324)
0.4 105.2 GO:0006470 protein dephosphorylation(GO:0006470)
0.4 30.3 GO:0050770 regulation of axonogenesis(GO:0050770)
0.4 0.8 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.4 8.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.4 5.7 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 6.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 12.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4 1.9 GO:0001839 neural plate morphogenesis(GO:0001839)
0.4 3.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998) regulation of fatty acid oxidation(GO:0046320)
0.4 4.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.4 1.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.3 12.9 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.3 19.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.3 1.7 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 3.7 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.3 1.4 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.3 10.0 GO:0006817 phosphate ion transport(GO:0006817)
0.3 6.3 GO:0030004 cellular monovalent inorganic cation homeostasis(GO:0030004)
0.3 14.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.3 6.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.3 14.3 GO:0048675 axon extension(GO:0048675)
0.3 1.6 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 4.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.3 9.1 GO:0016925 protein sumoylation(GO:0016925)
0.3 2.3 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.3 3.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.3 61.0 GO:0006813 potassium ion transport(GO:0006813)
0.3 3.5 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.3 4.5 GO:0039022 pronephric duct development(GO:0039022) nephric duct development(GO:0072176)
0.3 3.7 GO:0070828 heterochromatin organization(GO:0070828)
0.3 3.1 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.3 2.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 12.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.3 2.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 0.9 GO:0060911 cardiac cell fate commitment(GO:0060911) cardiac cell fate specification(GO:0060912)
0.3 5.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 1.7 GO:0003321 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993) positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.3 1.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.3 1.1 GO:0045471 response to ethanol(GO:0045471)
0.3 1.4 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.3 1.4 GO:0061056 sclerotome development(GO:0061056)
0.3 3.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.3 3.5 GO:0021984 adenohypophysis development(GO:0021984)
0.3 3.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 9.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.3 4.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.3 0.8 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.3 6.7 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.3 8.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.3 6.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.3 1.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 2.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.3 1.5 GO:0072576 liver morphogenesis(GO:0072576)
0.3 0.8 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.3 9.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.3 1.0 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.2 1.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 2.7 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.2 4.6 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.2 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.2 5.5 GO:0036303 lymph vessel morphogenesis(GO:0036303)
0.2 3.1 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 6.2 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.2 1.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 7.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.2 0.7 GO:0048569 post-embryonic organ development(GO:0048569)
0.2 15.4 GO:0007626 locomotory behavior(GO:0007626)
0.2 9.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 3.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 2.4 GO:0010770 positive regulation of cell morphogenesis involved in differentiation(GO:0010770)
0.2 5.5 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.2 48.3 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 39.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.2 0.6 GO:0019408 dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.2 1.3 GO:0006465 signal peptide processing(GO:0006465)
0.2 0.9 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.2 2.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 6.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 0.4 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.2 0.4 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 7.3 GO:0001935 endothelial cell proliferation(GO:0001935)
0.2 1.6 GO:0055015 ventricular cardiac muscle cell differentiation(GO:0055012) ventricular cardiac muscle cell development(GO:0055015)
0.2 2.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.2 1.2 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.2 9.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 3.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 11.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 4.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.2 2.9 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 1.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 3.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.2 6.1 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 0.9 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.2 5.8 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 0.6 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 1.8 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.7 GO:0016246 RNA interference(GO:0016246)
0.2 3.2 GO:0048854 brain morphogenesis(GO:0048854)
0.2 2.7 GO:0072114 pronephros morphogenesis(GO:0072114)
0.2 3.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.7 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 1.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.2 7.0 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.2 1.4 GO:0019827 stem cell population maintenance(GO:0019827)
0.2 1.3 GO:0007032 endosome organization(GO:0007032)
0.2 2.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 2.8 GO:0046847 filopodium assembly(GO:0046847)
0.2 3.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 0.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 0.6 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 4.4 GO:0043171 peptide catabolic process(GO:0043171)
0.1 7.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 3.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 12.5 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.1 1.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 7.1 GO:1902275 regulation of chromatin organization(GO:1902275)
0.1 1.8 GO:0018345 protein palmitoylation(GO:0018345)
0.1 6.9 GO:0051260 protein homooligomerization(GO:0051260)
0.1 1.0 GO:0007398 ectoderm development(GO:0007398)
0.1 3.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 13.3 GO:0070646 protein modification by small protein removal(GO:0070646)
0.1 3.3 GO:0003146 heart jogging(GO:0003146)
0.1 86.2 GO:0030182 neuron differentiation(GO:0030182)
0.1 0.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 5.2 GO:0016575 histone deacetylation(GO:0016575)
0.1 11.0 GO:0006821 chloride transport(GO:0006821)
0.1 20.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.3 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 3.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 2.3 GO:0060349 bone morphogenesis(GO:0060349)
0.1 1.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 2.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 2.0 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.1 0.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 18.3 GO:0007018 microtubule-based movement(GO:0007018)
0.1 2.6 GO:0007610 behavior(GO:0007610)
0.1 6.9 GO:0006475 internal protein amino acid acetylation(GO:0006475) histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394)
0.1 0.8 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 5.9 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.1 1.8 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.3 GO:0032456 endocytic recycling(GO:0032456)
0.1 3.5 GO:0034968 histone lysine methylation(GO:0034968)
0.1 5.3 GO:0007623 circadian rhythm(GO:0007623)
0.1 2.4 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.1 0.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.6 GO:0007416 synapse assembly(GO:0007416)
0.1 2.4 GO:0006284 base-excision repair(GO:0006284)
0.1 0.7 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 2.8 GO:1903052 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
0.1 12.8 GO:0007420 brain development(GO:0007420)
0.1 1.3 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.5 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.2 GO:1903312 regulation of mRNA catabolic process(GO:0061013) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.9 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 1.1 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 2.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0014821 phasic smooth muscle contraction(GO:0014821) regulation of digestive system process(GO:0044058)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 1.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 3.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0043649 aspartate metabolic process(GO:0006531) dicarboxylic acid catabolic process(GO:0043649)
0.0 5.9 GO:0007005 mitochondrion organization(GO:0007005)
0.0 0.3 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.3 GO:0006101 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0046500 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284) S-adenosylmethionine cycle(GO:0033353) S-adenosylhomocysteine metabolic process(GO:0046498) S-adenosylmethionine metabolic process(GO:0046500)
0.0 0.3 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 35.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
4.9 72.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
4.5 22.7 GO:0071439 clathrin complex(GO:0071439)
4.3 43.0 GO:0042583 chromaffin granule(GO:0042583)
3.9 15.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.8 11.5 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
3.5 21.1 GO:0005955 calcineurin complex(GO:0005955)
3.4 24.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.4 20.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.1 12.3 GO:0016600 flotillin complex(GO:0016600)
3.0 11.9 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
2.9 17.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
2.8 35.9 GO:0033270 paranode region of axon(GO:0033270)
2.4 14.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.3 18.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
2.1 12.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
2.1 16.4 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
1.9 17.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.9 11.3 GO:0043083 synaptic cleft(GO:0043083)
1.8 18.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
1.8 39.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
1.8 50.2 GO:0030125 clathrin vesicle coat(GO:0030125)
1.7 10.4 GO:0000938 GARP complex(GO:0000938)
1.6 68.4 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
1.6 8.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.6 6.3 GO:0043291 RAVE complex(GO:0043291)
1.5 31.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.4 5.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.4 5.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
1.4 4.2 GO:0042382 paraspeckles(GO:0042382)
1.4 58.7 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
1.4 20.7 GO:0031083 BLOC-1 complex(GO:0031083)
1.4 21.8 GO:0071564 npBAF complex(GO:0071564)
1.3 5.2 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
1.2 9.8 GO:0071914 prominosome(GO:0071914)
1.2 7.3 GO:0070062 extracellular exosome(GO:0070062)
1.2 2.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
1.2 2.3 GO:1990745 EARP complex(GO:1990745)
1.2 4.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.1 3.3 GO:0070578 RISC-loading complex(GO:0070578)
1.1 6.6 GO:0033557 Slx1-Slx4 complex(GO:0033557)
1.1 13.2 GO:0044295 axonal growth cone(GO:0044295)
1.1 10.9 GO:0034451 centriolar satellite(GO:0034451)
1.1 4.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.1 4.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.1 27.4 GO:0035371 microtubule plus-end(GO:0035371)
1.0 7.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.0 4.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
1.0 10.4 GO:1902555 endoribonuclease complex(GO:1902555)
1.0 9.7 GO:1990752 microtubule minus-end(GO:0036449) microtubule end(GO:1990752)
1.0 3.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.8 5.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.8 6.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.8 3.2 GO:0097268 cytoophidium(GO:0097268)
0.8 14.8 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.8 3.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.8 11.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 18.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.8 10.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.7 3.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.7 5.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.7 2.2 GO:0060077 inhibitory synapse(GO:0060077)
0.7 11.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 8.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.7 5.8 GO:0061700 GATOR2 complex(GO:0061700)
0.7 33.1 GO:0030426 growth cone(GO:0030426)
0.7 20.8 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.7 0.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.7 48.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.7 3.5 GO:0030314 junctional membrane complex(GO:0030314)
0.7 0.7 GO:0044297 cell body(GO:0044297)
0.7 4.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.7 14.8 GO:0043195 terminal bouton(GO:0043195)
0.7 2.0 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.7 2.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.6 57.7 GO:0043025 neuronal cell body(GO:0043025)
0.6 10.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.6 1.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.6 14.1 GO:0035102 PRC1 complex(GO:0035102)
0.6 3.5 GO:0016589 NURF complex(GO:0016589)
0.6 3.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.6 74.6 GO:0008021 synaptic vesicle(GO:0008021)
0.6 6.3 GO:0035101 FACT complex(GO:0035101)
0.6 5.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 22.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.5 10.8 GO:0097546 ciliary base(GO:0097546)
0.5 8.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.5 14.5 GO:0031201 SNARE complex(GO:0031201)
0.5 2.7 GO:0071203 WASH complex(GO:0071203)
0.5 6.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 5.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.5 91.1 GO:0030424 axon(GO:0030424)
0.5 12.8 GO:0005921 gap junction(GO:0005921)
0.5 19.9 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.5 212.8 GO:0043005 neuron projection(GO:0043005)
0.5 3.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 32.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 8.5 GO:0042734 presynaptic membrane(GO:0042734)
0.5 11.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.5 3.3 GO:0071818 BAT3 complex(GO:0071818)
0.5 9.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 21.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.5 9.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 3.6 GO:0070552 BRISC complex(GO:0070552)
0.4 15.6 GO:0030175 filopodium(GO:0030175)
0.4 2.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 14.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 3.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 3.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 10.8 GO:0000145 exocyst(GO:0000145)
0.4 4.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 2.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 23.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.4 2.0 GO:0034657 GID complex(GO:0034657)
0.4 3.8 GO:0000812 Swr1 complex(GO:0000812)
0.4 5.7 GO:0031209 SCAR complex(GO:0031209)
0.4 8.4 GO:0070822 Sin3-type complex(GO:0070822)
0.4 1.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.4 21.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 3.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.4 3.6 GO:0070449 elongin complex(GO:0070449)
0.4 18.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 6.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 4.5 GO:1990246 uniplex complex(GO:1990246)
0.3 5.8 GO:0030008 TRAPP complex(GO:0030008)
0.3 5.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 17.1 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.3 5.7 GO:0030667 secretory granule membrane(GO:0030667)
0.3 7.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 3.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 12.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 11.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 1.3 GO:0005787 signal peptidase complex(GO:0005787)
0.3 1.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 10.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 2.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 6.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 1.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 4.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 9.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 3.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.3 2.3 GO:0097225 sperm midpiece(GO:0097225)
0.3 1.9 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.3 1.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 4.2 GO:0036126 sperm flagellum(GO:0036126)
0.3 1.0 GO:0032019 mitochondrial cloud(GO:0032019)
0.3 5.3 GO:0032153 cell division site(GO:0032153)
0.3 3.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.2 2.2 GO:0008180 COP9 signalosome(GO:0008180)
0.2 13.0 GO:0016342 catenin complex(GO:0016342)
0.2 11.4 GO:0030027 lamellipodium(GO:0030027)
0.2 1.2 GO:0070390 transcription export complex 2(GO:0070390)
0.2 5.4 GO:0071141 SMAD protein complex(GO:0071141)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 2.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 0.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 4.2 GO:0070461 SAGA-type complex(GO:0070461)
0.2 1.9 GO:0000792 heterochromatin(GO:0000792)
0.2 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 13.5 GO:0005871 kinesin complex(GO:0005871)
0.2 4.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 3.2 GO:0030990 intraciliary transport particle(GO:0030990)
0.2 8.3 GO:0008305 integrin complex(GO:0008305)
0.2 9.5 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.2 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 5.1 GO:0060293 germ plasm(GO:0060293)
0.2 2.3 GO:0048179 activin receptor complex(GO:0048179)
0.2 0.6 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.2 6.0 GO:0014069 postsynaptic density(GO:0014069)
0.2 1.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 5.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 4.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.7 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 6.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 6.4 GO:0016592 mediator complex(GO:0016592)
0.1 4.2 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.9 GO:0044447 axoneme part(GO:0044447)
0.1 10.3 GO:0005929 cilium(GO:0005929)
0.1 0.6 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 4.0 GO:0016605 PML body(GO:0016605)
0.1 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 15.4 GO:0005874 microtubule(GO:0005874)
0.1 3.3 GO:0005776 autophagosome(GO:0005776)
0.1 1.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 3.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 7.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 23.3 GO:0000139 Golgi membrane(GO:0000139)
0.1 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.5 GO:0030141 secretory granule(GO:0030141)
0.1 5.3 GO:0099568 cell cortex(GO:0005938) cytoplasmic region(GO:0099568)
0.1 355.3 GO:0005634 nucleus(GO:0005634)
0.1 0.4 GO:0005838 proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0 37.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.1 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 37.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
5.9 29.4 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
5.9 23.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
5.8 34.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
5.7 34.2 GO:0048156 tau protein binding(GO:0048156)
5.4 21.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
4.4 30.9 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
4.0 12.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
3.7 26.0 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
3.6 71.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
3.5 21.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
3.3 29.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
3.3 19.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
3.2 9.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.1 9.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
3.0 9.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
2.9 40.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
2.8 16.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
2.7 8.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
2.7 24.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.6 15.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
2.6 12.9 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
2.5 12.6 GO:0043295 glutathione binding(GO:0043295)
2.4 17.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
2.4 7.2 GO:0005252 open rectifier potassium channel activity(GO:0005252)
2.4 12.0 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
2.3 9.4 GO:0030626 U12 snRNA binding(GO:0030626)
2.3 11.4 GO:0004127 cytidylate kinase activity(GO:0004127)
2.1 19.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
2.1 10.4 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
2.1 12.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
2.1 16.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
2.0 18.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.0 7.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
2.0 9.9 GO:0008046 axon guidance receptor activity(GO:0008046)
1.9 23.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.9 5.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.9 13.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.9 13.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.8 12.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.8 14.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
1.8 8.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
1.8 5.3 GO:0047690 aspartyltransferase activity(GO:0047690)
1.8 7.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
1.8 12.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.7 24.5 GO:0008327 methyl-CpG binding(GO:0008327)
1.7 13.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.7 5.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
1.7 6.7 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.7 8.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.6 19.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.6 1.6 GO:0017081 chloride channel regulator activity(GO:0017081)
1.6 7.8 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.5 4.5 GO:1990715 mRNA CDS binding(GO:1990715)
1.5 7.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
1.4 5.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.4 12.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.4 8.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.4 5.7 GO:0071889 14-3-3 protein binding(GO:0071889)
1.4 8.3 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.4 24.7 GO:0033691 sialic acid binding(GO:0033691)
1.4 6.8 GO:0050699 WW domain binding(GO:0050699)
1.2 18.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.2 59.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.2 19.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.2 5.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
1.2 3.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.2 12.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.2 4.6 GO:0033149 FFAT motif binding(GO:0033149)
1.2 27.6 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
1.2 4.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
1.1 9.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.1 15.7 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 14.4 GO:0030507 spectrin binding(GO:0030507)
1.1 3.3 GO:0019777 Atg12 transferase activity(GO:0019777)
1.1 16.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
1.1 4.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.1 4.3 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
1.1 20.5 GO:0015026 coreceptor activity(GO:0015026)
1.1 7.6 GO:0019809 spermidine binding(GO:0019809)
1.1 3.2 GO:0046978 MHC class I protein binding(GO:0042288) TAP1 binding(GO:0046978)
1.1 20.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.1 4.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
1.1 31.7 GO:0030165 PDZ domain binding(GO:0030165)
1.0 34.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
1.0 5.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
1.0 28.0 GO:0017080 sodium channel regulator activity(GO:0017080)
1.0 5.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.0 4.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
1.0 8.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.0 16.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
1.0 39.8 GO:0017075 syntaxin-1 binding(GO:0017075)
1.0 15.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
1.0 84.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.0 17.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
1.0 22.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.0 6.7 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.9 2.8 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.9 2.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.9 2.8 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.9 10.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.9 2.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.9 6.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.9 12.0 GO:0070840 dynein complex binding(GO:0070840)
0.9 30.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.9 7.7 GO:0004359 glutaminase activity(GO:0004359)
0.9 3.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.8 3.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.8 71.8 GO:0030276 clathrin binding(GO:0030276)
0.8 5.8 GO:0070728 leucine binding(GO:0070728)
0.8 2.4 GO:0097643 amylin receptor activity(GO:0097643)
0.8 11.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.8 8.9 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.8 3.2 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.8 3.2 GO:0003883 CTP synthase activity(GO:0003883)
0.8 4.0 GO:0070412 R-SMAD binding(GO:0070412)
0.8 10.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.8 3.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.8 14.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.8 10.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.8 6.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.8 21.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.8 3.8 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.7 22.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.7 12.5 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.7 2.9 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.7 11.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.7 11.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.7 2.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.7 11.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.7 3.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.7 9.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.7 15.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 4.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.7 5.3 GO:0004067 asparaginase activity(GO:0004067)
0.7 8.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.7 4.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 5.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 24.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.6 10.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.6 5.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.6 6.9 GO:0030552 cAMP binding(GO:0030552)
0.6 15.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.6 6.1 GO:0005042 netrin receptor activity(GO:0005042)
0.6 1.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 4.8 GO:0030619 U1 snRNA binding(GO:0030619)
0.6 7.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.6 4.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 14.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 12.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 6.4 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.6 6.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 15.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.6 11.3 GO:0003785 actin monomer binding(GO:0003785)
0.6 15.0 GO:0010857 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.6 9.4 GO:0045159 myosin II binding(GO:0045159)
0.5 1.6 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.5 10.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 3.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.5 11.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.5 24.6 GO:0044325 ion channel binding(GO:0044325)
0.5 2.0 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.5 7.0 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.5 2.5 GO:0051219 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.5 19.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5 22.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 2.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 4.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 6.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.5 30.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 2.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 2.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.5 1.8 GO:0016417 S-acyltransferase activity(GO:0016417)
0.4 1.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 1.3 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.4 55.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 11.5 GO:0015248 sterol transporter activity(GO:0015248)
0.4 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.4 1.2 GO:0036310 annealing helicase activity(GO:0036310)
0.4 23.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.4 5.5 GO:0035064 methylated histone binding(GO:0035064)
0.4 6.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 9.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 6.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.4 6.5 GO:0008301 DNA binding, bending(GO:0008301)
0.4 3.4 GO:0004985 opioid receptor activity(GO:0004985)
0.4 17.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.4 6.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 37.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.4 22.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 5.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 1.8 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.4 1.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 128.6 GO:0015631 tubulin binding(GO:0015631)
0.3 13.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 31.7 GO:0045296 cadherin binding(GO:0045296)
0.3 7.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.3 6.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.6 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.3 4.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 2.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 16.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 15.4 GO:0017124 SH3 domain binding(GO:0017124)
0.3 1.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 51.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 3.7 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.3 2.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 9.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 1.4 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 2.5 GO:0004096 catalase activity(GO:0004096)
0.3 5.6 GO:0097602 cullin family protein binding(GO:0097602)
0.3 1.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 6.4 GO:0030371 translation repressor activity(GO:0030371)
0.3 8.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 6.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.3 19.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 1.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 4.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 3.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 4.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 9.4 GO:0008013 beta-catenin binding(GO:0008013)
0.3 2.0 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 9.1 GO:0030145 manganese ion binding(GO:0030145)
0.2 3.4 GO:0070628 proteasome binding(GO:0070628)
0.2 1.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 3.8 GO:0070122 isopeptidase activity(GO:0070122)
0.2 1.7 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.2 GO:0043531 ADP binding(GO:0043531)
0.2 2.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 22.1 GO:0000149 SNARE binding(GO:0000149)
0.2 1.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 2.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 7.9 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.7 GO:0004935 adrenergic receptor activity(GO:0004935)
0.2 6.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.5 GO:0016405 CoA-ligase activity(GO:0016405)
0.2 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 8.3 GO:0005109 frizzled binding(GO:0005109)
0.2 3.0 GO:0002039 p53 binding(GO:0002039)
0.2 12.6 GO:0051287 NAD binding(GO:0051287)
0.2 1.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 3.9 GO:0022829 wide pore channel activity(GO:0022829)
0.2 9.8 GO:0031491 nucleosome binding(GO:0031491)
0.2 1.0 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 2.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 3.9 GO:0017069 snRNA binding(GO:0017069)
0.2 1.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 2.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 3.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 1.9 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.2 4.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 5.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.2 1.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 4.0 GO:0000339 RNA cap binding(GO:0000339)
0.2 6.2 GO:0032452 histone demethylase activity(GO:0032452)
0.2 5.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 66.2 GO:0003924 GTPase activity(GO:0003924)
0.2 0.6 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.2 5.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 2.5 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 0.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 4.2 GO:0016208 AMP binding(GO:0016208)
0.2 6.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 1.5 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 2.8 GO:0019894 kinesin binding(GO:0019894)
0.1 0.7 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 16.0 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.1 GO:0003684 damaged DNA binding(GO:0003684)
0.1 13.3 GO:0005179 hormone activity(GO:0005179)
0.1 3.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 7.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 14.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 1.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 21.4 GO:0042802 identical protein binding(GO:0042802)
0.1 4.8 GO:0005178 integrin binding(GO:0005178)
0.1 0.9 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.7 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 2.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 10.3 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.1 38.8 GO:0046983 protein dimerization activity(GO:0046983)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.9 GO:0042393 histone binding(GO:0042393)
0.1 0.3 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 2.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 27.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.8 GO:0005112 Notch binding(GO:0005112)
0.1 5.0 GO:0005507 copper ion binding(GO:0005507)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 4.7 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.3 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.1 10.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 13.7 GO:0003682 chromatin binding(GO:0003682)
0.1 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 4.2 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.3 GO:0030060 malate dehydrogenase activity(GO:0016615) L-malate dehydrogenase activity(GO:0030060)
0.1 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 4.6 GO:0008201 heparin binding(GO:0008201)
0.1 1.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 3.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 14.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 10.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 12.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0046332 SMAD binding(GO:0046332)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 4.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 13.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.5 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 19.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 6.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 23.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.6 21.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
1.5 32.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.2 27.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.1 43.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
1.0 20.2 PID ARF 3PATHWAY Arf1 pathway
1.0 11.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.9 11.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.8 9.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.8 15.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.7 25.4 PID BMP PATHWAY BMP receptor signaling
0.7 12.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.7 7.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 2.9 PID IGF1 PATHWAY IGF1 pathway
0.5 3.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 26.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 6.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.5 4.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.5 8.1 PID ARF6 PATHWAY Arf6 signaling events
0.4 8.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 5.7 PID RHOA PATHWAY RhoA signaling pathway
0.4 12.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 10.8 PID INSULIN PATHWAY Insulin Pathway
0.3 2.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 8.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.3 7.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 5.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 4.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 3.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 3.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 2.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 8.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 4.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 4.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 2.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 10.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 4.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 30.0 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
4.5 13.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
4.2 16.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
2.7 40.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
2.0 33.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.9 21.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.8 24.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
1.8 12.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.8 18.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.5 16.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.4 14.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.3 18.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.3 16.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
1.2 12.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.1 24.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.0 8.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.0 13.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.0 14.6 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.9 22.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.9 8.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.9 27.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.8 12.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.8 8.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.8 0.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.8 6.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7 20.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.7 10.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.7 4.2 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.7 12.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.7 10.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 15.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.6 13.0 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.6 14.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 15.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 3.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 5.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4 6.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 7.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 15.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.4 3.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 3.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 3.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 31.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 2.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.3 4.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.3 20.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 8.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 2.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 4.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 2.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 14.5 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.2 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 7.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 1.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 5.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.2 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 3.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 2.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 8.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 3.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions