Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for wt1a+wt1b

Z-value: 1.44

Motif logo

Transcription factors associated with wt1a+wt1b

Gene Symbol Gene ID Gene Info
ENSDARG00000007990 WT1 transcription factor b
ENSDARG00000031420 WT1 transcription factor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
wt1bdr11_v1_chr18_-_45617146_45617146-0.251.5e-02Click!
wt1adr11_v1_chr25_-_15214161_15214161-0.151.6e-01Click!

Activity profile of wt1a+wt1b motif

Sorted Z-values of wt1a+wt1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_48111285 12.67 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr7_-_10606 11.97 ENSDART00000192650
ENSDART00000186761

chr2_+_59015878 11.81 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr13_+_22480857 10.75 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr3_+_32526799 10.71 ENSDART00000185755
si:ch73-367p23.2
chr2_-_22535 10.60 ENSDART00000157877

chr3_-_1190132 10.46 ENSDART00000149709
single-pass membrane protein with aspartate-rich tail 1a
chr2_-_44282796 9.94 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr3_+_32526263 9.94 ENSDART00000150897
si:ch73-367p23.2
chr1_-_59232267 9.22 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr18_+_5549672 8.26 ENSDART00000184970
nicotinamide nucleotide transhydrogenase 2
chr25_+_150570 7.99 ENSDART00000170892
ADAM metallopeptidase domain 10b
chr22_+_396840 7.76 ENSDART00000163198
capping protein (actin filament) muscle Z-line, beta
chr21_-_5056812 7.63 ENSDART00000139713
ENSDART00000140859
zgc:77838
chr17_-_125091 7.63 ENSDART00000158825
actin, alpha, cardiac muscle 1b
chr24_+_42131564 7.61 ENSDART00000153854
WW domain containing E3 ubiquitin protein ligase 1
chr2_+_58221163 7.57 ENSDART00000157939

chr19_+_33701558 7.47 ENSDART00000147226
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_-_31435137 7.46 ENSDART00000057441
reticulon 1a
chr9_-_39005317 7.29 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr25_-_37501371 7.24 ENSDART00000160498

chr10_+_32561317 6.97 ENSDART00000109029
microtubule-associated protein 6a
chr14_+_2243 6.92 ENSDART00000191193
cytokine like 1
chr25_+_34984333 6.85 ENSDART00000154760
coiled-coil domain containing 136b
chr23_+_28731379 6.68 ENSDART00000047378
cortistatin
chr2_-_48753873 6.62 ENSDART00000189556

chr20_-_14665002 6.56 ENSDART00000152816
secernin 2
chr4_+_41602 6.19 ENSDART00000159640
putative homeodomain transcription factor 2
chr11_-_97817 6.18 ENSDART00000092903
engulfment and cell motility 2
chr19_+_31771270 6.04 ENSDART00000147474
stathmin 2b
chr7_-_18168493 5.98 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr22_-_193234 5.88 ENSDART00000131067
F-box protein 42
chr3_-_62380146 5.85 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr2_+_24304854 5.68 ENSDART00000078972
fat storage-inducing transmembrane protein 1
chr19_+_33701366 5.57 ENSDART00000162517
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_54840124 5.53 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr1_+_57371447 5.51 ENSDART00000152229
ENSDART00000181077
si:dkey-27j5.3
chr7_-_57949117 5.47 ENSDART00000138803
ankyrin 2b, neuronal
chr3_+_5575313 5.43 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
chr1_-_14234076 5.39 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr16_-_6821927 5.37 ENSDART00000149070
ENSDART00000149570
myelin basic protein b
chr1_-_14233815 5.34 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr20_-_54381034 5.34 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr3_+_50312422 5.23 ENSDART00000157689
growth arrest-specific 7a
chr24_+_24831727 5.20 ENSDART00000080969
tripartite motif containing 55b
chr16_-_12953739 5.16 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr2_-_9646857 5.16 ENSDART00000056901
zgc:153615
chr6_-_13408680 5.13 ENSDART00000151566
formin-like 2b
chr21_-_22114625 5.10 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr24_+_42127983 5.05 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
WW domain containing E3 ubiquitin protein ligase 1
chr19_+_33701734 5.01 ENSDART00000123270
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_103136 4.99 ENSDART00000173308
ENSDART00000162982
engulfment and cell motility 2
chr8_+_8298439 4.95 ENSDART00000170566
SRSF protein kinase 3
chr2_+_38924975 4.90 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr21_-_308852 4.88 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr7_-_6592142 4.78 ENSDART00000160137
potassium inwardly-rectifying channel, subfamily J, member 10a
chr16_-_44399335 4.77 ENSDART00000165058
regulating synaptic membrane exocytosis 2a
chr11_+_41560792 4.71 ENSDART00000127292
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr16_-_44349845 4.67 ENSDART00000170932
regulating synaptic membrane exocytosis 2a
chr15_-_33925851 4.66 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr14_+_22172047 4.64 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr8_+_54284961 4.64 ENSDART00000122692
plexin D1
chr20_+_52554352 4.60 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr17_+_53311618 4.59 ENSDART00000166517
ankyrin repeat and SOCS box containing 2b
chr9_-_54001502 4.52 ENSDART00000085253
midline 1
chr11_+_40649412 4.50 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr14_-_12837052 4.46 ENSDART00000165004
ENSDART00000043180
glutamate receptor, ionotropic, AMPA 3b
chr11_+_45461853 4.45 ENSDART00000173409
son of sevenless homolog 1 (Drosophila)
chr1_+_54677173 4.43 ENSDART00000114705
G protein-coupled receptor, class C, group 5, member Bb
chr23_-_637347 4.41 ENSDART00000132175
L1 cell adhesion molecule, paralog b
chr18_+_54354 4.34 ENSDART00000097163
zgc:158482
chr8_+_23165749 4.34 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr5_+_36614196 4.33 ENSDART00000150574
neuro-oncological ventral antigen 1
chr3_+_1211242 4.32 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr25_+_35706493 4.30 ENSDART00000176741
kinesin family member 21A
chr20_+_54356272 4.25 ENSDART00000145735
zinc finger protein 410
chr17_-_20711735 4.24 ENSDART00000150056
ankyrin 3b
chr14_-_237130 4.17 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr23_-_3703569 4.10 ENSDART00000143731
protein kinase C and casein kinase substrate in neurons 1a
chr18_-_50845804 4.09 ENSDART00000158517
si:cabz01113374.3
chr18_-_15373620 4.08 ENSDART00000031752
regulatory factor X, 4
chr14_-_12837432 4.07 ENSDART00000178444
glutamate receptor, ionotropic, AMPA 3b
chr1_+_54908895 4.05 ENSDART00000145652
golgin A7 family, member Ba
chr13_+_12739283 4.03 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr15_+_1397811 4.02 ENSDART00000102125
schwannomin interacting protein 1
chr7_+_48460239 3.97 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr8_+_8166285 3.94 ENSDART00000147940
plexin B3
chr6_+_28203 3.93 ENSDART00000191561

chr17_+_53311243 3.91 ENSDART00000160241
ENSDART00000160009
ENSDART00000162239
ankyrin repeat and SOCS box containing 2b
chr13_-_51922290 3.90 ENSDART00000168648
serum response factor b
chr21_+_13861589 3.89 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr21_+_11468934 3.87 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr6_+_59808677 3.86 ENSDART00000164469
calcium/calmodulin-dependent serine protein kinase b
chr5_-_6433577 3.86 ENSDART00000160439

chr20_-_52928541 3.82 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr1_+_29858032 3.77 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr1_-_25936677 3.76 ENSDART00000146488
ENSDART00000136321
myozenin 2b
chr5_+_64739762 3.73 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfactomedin 1a
chr16_-_563235 3.72 ENSDART00000016303
iroquois homeobox 2a
chr17_-_43466317 3.67 ENSDART00000155313
heat shock protein 4 like
chr7_+_74150839 3.62 ENSDART00000160195
protein phosphatase 1, catalytic subunit, beta isoform, like
chr16_+_12240605 3.56 ENSDART00000060056
triosephosphate isomerase 1b
chr8_-_54223316 3.53 ENSDART00000018054
thyrotropin-releasing hormone
chr11_+_6819050 3.52 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr13_+_25428677 3.50 ENSDART00000186284
si:dkey-51a16.9
chr16_+_1803462 3.48 ENSDART00000183974
glutamate ionotropic receptor kainate type subunit 2
chr24_+_42132962 3.46 ENSDART00000187739
WW domain containing E3 ubiquitin protein ligase 1
chr13_+_421231 3.43 ENSDART00000188212
ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr19_+_63567 3.43 ENSDART00000165657
ENSDART00000165183
zinc fingers and homeoboxes 2b
chr8_-_9118958 3.36 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr18_-_10298162 3.35 ENSDART00000007520
leucine rich repeat containing 4.2
chr23_+_44732863 3.33 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr5_-_72289648 3.32 ENSDART00000037691
T-box 5a
chr21_+_11468642 3.27 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr10_+_44940693 3.22 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr12_+_5189776 3.21 ENSDART00000081298
leucine-rich, glioma inactivated 1b
chr10_-_24343507 3.21 ENSDART00000002974
phosphatidylinositol transfer protein, alpha b
chr8_-_22739757 3.14 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr4_+_77948970 3.11 ENSDART00000149636
protein kinase C and casein kinase substrate in neurons 2
chr20_-_54462551 3.11 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr5_-_25066780 3.10 ENSDART00000002118
ENSDART00000182575
patatin-like phospholipase domain containing 7b
chr12_-_49165751 3.09 ENSDART00000148491
ENSDART00000112479
acyl-CoA dehydrogenase short/branched chain
chr25_-_19395476 3.08 ENSDART00000182622
microtubule-associated protein 1Ab
chr9_-_2572790 2.99 ENSDART00000135076
ENSDART00000016710
secernin 3
chr5_+_51443009 2.99 ENSDART00000083350
Ras protein-specific guanine nucleotide-releasing factor 2b
chr21_-_45878872 2.98 ENSDART00000029763
sap30-like
chr11_+_2198831 2.97 ENSDART00000160515
homeobox C6b
chr9_-_2573121 2.96 ENSDART00000181340
secernin 3
chr15_-_14486534 2.94 ENSDART00000179368
numb homolog (Drosophila)-like
chr23_-_19953089 2.94 ENSDART00000153828
ATPase plasma membrane Ca2+ transporting 3b
chr6_-_52428826 2.93 ENSDART00000047399
matrix metallopeptidase 24
chr10_+_37500234 2.91 ENSDART00000132096
ENSDART00000099473
musashi RNA-binding protein 2a
chr12_+_9880493 2.88 ENSDART00000055019
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr16_-_42152145 2.87 ENSDART00000038748
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr21_+_103194 2.86 ENSDART00000162755
zyg-11 related, cell cycle regulator
chr7_-_73702063 2.80 ENSDART00000130539

chr22_-_600016 2.78 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr24_-_25364775 2.78 ENSDART00000151915
patched domain containing 1
chr20_-_39219537 2.78 ENSDART00000005764
cytochrome P450, family 39, subfamily A, polypeptide 1
chr11_-_44030962 2.76 ENSDART00000171910

chr19_+_233143 2.75 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr6_+_58492201 2.75 ENSDART00000156375
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr11_+_1796426 2.68 ENSDART00000173330
low density lipoprotein receptor-related protein 1Aa
chr25_-_19395156 2.66 ENSDART00000155335
microtubule-associated protein 1Ab
chr15_-_8517555 2.60 ENSDART00000140213
neuronal PAS domain protein 1
chr25_+_35774544 2.60 ENSDART00000034737
ENSDART00000188162
copine VIII
chr16_-_12914288 2.59 ENSDART00000184221
calcium channel, voltage-dependent, gamma subunit 8b
chr12_+_18606140 2.58 ENSDART00000161128
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr19_-_19442983 2.58 ENSDART00000052649
sb:cb649
chr23_+_44644911 2.55 ENSDART00000140799
zgc:85858
chr9_-_1434484 2.55 ENSDART00000093412
oxysterol binding protein-like 6
chr21_+_38312549 2.53 ENSDART00000065159
zgc:158291
chr20_+_39250673 2.50 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr23_+_19564392 2.50 ENSDART00000144746
ATPase H+ transporting accessory protein 1 like b
chr6_+_31684 2.50 ENSDART00000188853
ENSDART00000184553

chr7_+_10701938 2.48 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr6_+_2271559 2.47 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr14_+_11103718 2.47 ENSDART00000161311
neurite extension and migration factor b
chr22_+_12366516 2.46 ENSDART00000157802
R3H domain containing 1
chr9_-_30363770 2.46 ENSDART00000147030
synaptotagmin-like 5
chr12_-_26430507 2.45 ENSDART00000153214
synaptopodin 2-like b
chr10_-_35542071 2.45 ENSDART00000162139
si:ch211-244c8.4
chr16_-_563732 2.42 ENSDART00000183394
iroquois homeobox 2a
chr2_+_3595333 2.42 ENSDART00000041052
complement component 1, q subcomponent-like 3b
chr9_+_51891 2.41 ENSDART00000163529
zgc:158316
chr6_-_58828113 2.41 ENSDART00000180934
kinesin family member 5A, b
chr19_+_41701660 2.39 ENSDART00000033362
GATA zinc finger domain containing 2B
chr20_-_1268863 2.37 ENSDART00000109321
ENSDART00000027119
large tumor suppressor kinase 1
chr23_+_9560797 2.37 ENSDART00000180014
adhesion regulating molecule 1
chr2_-_11912347 2.36 ENSDART00000023851
abhydrolase domain containing 3
chr7_-_51627019 2.36 ENSDART00000174111
NHS-like 2
chr2_-_7246338 2.34 ENSDART00000186735
zgc:153115
chr25_-_207214 2.33 ENSDART00000193448

chr5_-_52277643 2.32 ENSDART00000010757
repulsive guidance molecule family member b
chr3_-_6767440 2.32 ENSDART00000156174
microtubule associated serine/threonine kinase 1b
chr16_+_10963602 2.31 ENSDART00000141032
POU class 2 homeobox 2a
chr15_-_14552101 2.30 ENSDART00000171169
numb homolog (Drosophila)-like
chr8_+_2656231 2.28 ENSDART00000160833
family with sequence similarity 102, member Aa
chr22_+_465269 2.26 ENSDART00000145767
cadherin, EGF LAG seven-pass G-type receptor 2
chr19_+_30633453 2.26 ENSDART00000052124
family with sequence similarity 49, member A-like
chr10_+_45128375 2.26 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr16_+_23600041 2.24 ENSDART00000186918
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr3_+_7617353 2.23 ENSDART00000165551
zgc:109949
chr2_-_16216568 2.21 ENSDART00000173758
Rho guanine nucleotide exchange factor (GEF) 4
chr14_-_2369849 2.20 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
protocadherin b
chr4_-_837768 2.19 ENSDART00000185280
ENSDART00000135618
sine oculis binding protein homolog (Drosophila) b
chr2_+_26303627 2.19 ENSDART00000040278
ephrin-A2a
chr21_+_233271 2.12 ENSDART00000171440
DTW domain containing 2
chr24_+_33622769 2.11 ENSDART00000079342
dynein, axonemal, heavy chain 5 like
chr10_-_40939303 2.10 ENSDART00000134295
bone morphogenetic protein 1b
chr2_+_49232559 2.09 ENSDART00000154285
ENSDART00000175147
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr20_+_23501535 2.08 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr5_+_9348284 2.08 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr6_-_16406210 2.07 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr21_+_37445871 2.07 ENSDART00000076333
phosphoglycerate kinase 1
chr9_+_19489304 2.07 ENSDART00000151920
si:ch211-140m22.7
chr23_+_6752828 2.06 ENSDART00000105179
zgc:158254
chr22_-_18112374 2.04 ENSDART00000191154
neurocan b
chr10_-_1718395 2.03 ENSDART00000137620
si:ch73-46j18.5
chr17_-_22048233 2.02 ENSDART00000155203
tau tubulin kinase 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of wt1a+wt1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:1903792 negative regulation of anion transport(GO:1903792)
2.1 8.3 GO:0006740 NADPH regeneration(GO:0006740)
1.6 7.8 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
1.5 9.2 GO:0035332 positive regulation of hippo signaling(GO:0035332)
1.2 6.0 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
1.2 3.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.1 3.3 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
1.1 5.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.9 3.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.8 12.7 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.7 4.8 GO:0036268 swimming(GO:0036268)
0.6 2.5 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6 10.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 4.9 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.5 3.8 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.5 6.8 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.5 2.1 GO:0018343 protein farnesylation(GO:0018343)
0.5 4.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5 11.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 4.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.5 3.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.5 2.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.5 2.8 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.5 7.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.5 1.8 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.5 4.5 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.5 7.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.4 4.7 GO:0098900 regulation of action potential(GO:0098900)
0.4 3.7 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.4 8.6 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 1.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 2.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 1.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 2.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.3 8.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.3 5.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.3 1.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.3 1.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.3 5.4 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.3 1.5 GO:0034505 tooth mineralization(GO:0034505)
0.3 2.4 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 8.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.3 8.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.3 1.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.3 3.9 GO:0043248 proteasome assembly(GO:0043248)
0.3 1.3 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.2 11.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 2.8 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 1.4 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 2.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 4.1 GO:0097320 membrane tubulation(GO:0097320)
0.2 2.3 GO:0021754 facial nucleus development(GO:0021754)
0.2 1.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 1.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 2.0 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 1.5 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.7 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 4.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 1.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.9 GO:1904861 excitatory synapse assembly(GO:1904861)
0.2 2.4 GO:0046620 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.2 2.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 3.7 GO:0030316 osteoclast differentiation(GO:0030316)
0.2 1.3 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.2 3.2 GO:0015693 magnesium ion transport(GO:0015693)
0.2 2.1 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 3.3 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 1.8 GO:0032288 myelin assembly(GO:0032288)
0.2 0.7 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 1.6 GO:0021794 thalamus development(GO:0021794)
0.2 3.4 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.2 1.8 GO:0006868 glutamine transport(GO:0006868)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 13.8 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.2 0.5 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.2 2.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 11.5 GO:0042552 myelination(GO:0042552)
0.1 3.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.8 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 2.8 GO:0050890 cognition(GO:0050890)
0.1 2.5 GO:0030878 thyroid gland development(GO:0030878)
0.1 5.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 4.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.9 GO:0060034 notochord cell differentiation(GO:0060034)
0.1 3.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 2.7 GO:0051289 protein homotetramerization(GO:0051289)
0.1 2.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 1.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 3.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 1.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 13.3 GO:0006909 phagocytosis(GO:0006909)
0.1 0.7 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 4.5 GO:0001706 endoderm formation(GO:0001706)
0.1 4.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.6 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 1.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.9 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 5.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 10.7 GO:0007626 locomotory behavior(GO:0007626)
0.1 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.2 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 4.6 GO:0006414 translational elongation(GO:0006414)
0.1 2.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 2.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 24.4 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 4.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.9 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.9 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 3.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.8 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 6.3 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.9 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 2.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 3.0 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 5.3 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 1.0 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 4.3 GO:0060548 negative regulation of cell death(GO:0060548)
0.0 2.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 8.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 7.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.3 GO:0071711 basement membrane organization(GO:0071711)
0.0 1.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.1 GO:0045010 actin nucleation(GO:0045010)
0.0 5.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.7 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 1.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 4.5 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.2 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.9 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 2.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.7 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.7 GO:0022900 electron transport chain(GO:0022900)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0008290 F-actin capping protein complex(GO:0008290)
1.7 10.3 GO:0070062 extracellular exosome(GO:0070062)
0.9 15.3 GO:0043209 myelin sheath(GO:0043209)
0.8 10.5 GO:1990246 uniplex complex(GO:1990246)
0.7 4.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 2.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.5 7.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 7.4 GO:0005869 dynactin complex(GO:0005869)
0.4 2.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.4 8.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 11.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.4 2.7 GO:0043194 axon initial segment(GO:0043194)
0.4 4.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 16.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 1.8 GO:0033270 paranode region of axon(GO:0033270)
0.4 4.4 GO:0044295 axonal growth cone(GO:0044295)
0.4 3.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 5.5 GO:0030315 T-tubule(GO:0030315)
0.3 3.3 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.3 4.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 3.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 10.7 GO:0031941 filamentous actin(GO:0031941)
0.2 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 2.1 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 2.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.8 GO:0005844 polysome(GO:0005844)
0.1 4.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 5.4 GO:0030426 growth cone(GO:0030426)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.7 GO:0016234 inclusion body(GO:0016234)
0.1 3.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 8.8 GO:0005871 kinesin complex(GO:0005871)
0.1 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 7.3 GO:0030018 Z disc(GO:0030018)
0.1 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 6.2 GO:0005875 microtubule associated complex(GO:0005875)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 6.6 GO:0000786 nucleosome(GO:0000786)
0.1 4.9 GO:0030141 secretory granule(GO:0030141)
0.1 5.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 12.3 GO:0097060 synaptic membrane(GO:0097060)
0.0 8.1 GO:0045202 synapse(GO:0045202)
0.0 6.7 GO:0099503 exocytic vesicle(GO:0070382) secretory vesicle(GO:0099503)
0.0 0.9 GO:0008278 cohesin complex(GO:0008278)
0.0 2.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.7 GO:0034704 calcium channel complex(GO:0034704)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 6.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 13.1 GO:0043005 neuron projection(GO:0043005)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 6.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.8 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0000776 kinetochore(GO:0000776)
0.0 1.4 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
2.5 12.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
2.1 8.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
1.3 3.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.9 3.6 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.8 2.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.6 3.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 8.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 4.5 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 1.7 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.5 10.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.5 2.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.5 3.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 12.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.4 1.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 2.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 7.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 3.8 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.4 3.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.4 1.1 GO:0004061 arylformamidase activity(GO:0004061)
0.4 5.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 4.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.3 4.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 5.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.3 1.6 GO:0060182 apelin receptor activity(GO:0060182)
0.3 3.1 GO:0005522 profilin binding(GO:0005522)
0.3 1.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.3 2.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 1.2 GO:0071253 connexin binding(GO:0071253)
0.3 2.6 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 5.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3 13.8 GO:0044325 ion channel binding(GO:0044325)
0.3 13.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 2.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 7.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.9 GO:0016803 ether hydrolase activity(GO:0016803)
0.2 0.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 11.2 GO:0017124 SH3 domain binding(GO:0017124)
0.2 1.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 1.7 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 1.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 3.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 10.3 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.2 5.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 1.3 GO:0032977 membrane insertase activity(GO:0032977)
0.2 1.0 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 3.0 GO:0033691 sialic acid binding(GO:0033691)
0.2 3.3 GO:0001671 ATPase activator activity(GO:0001671)
0.2 4.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 3.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 3.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 4.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 4.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 18.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 3.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.3 GO:0015026 coreceptor activity(GO:0015026)
0.1 5.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 9.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 2.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 11.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 36.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.6 GO:0042805 actinin binding(GO:0042805)
0.1 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.5 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 2.0 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.1 10.1 GO:0005179 hormone activity(GO:0005179)
0.1 1.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 2.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 3.0 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 2.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 11.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 15.0 GO:0015631 tubulin binding(GO:0015631)
0.0 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 2.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 5.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 10.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 3.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 8.5 GO:0005543 phospholipid binding(GO:0005543)
0.0 6.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 8.8 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.3 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 9.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 8.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.3 PID BMP PATHWAY BMP receptor signaling
0.1 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 4.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 6.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.5 6.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.5 8.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 4.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 4.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 7.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 1.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 4.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 16.1 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.2 3.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 5.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 2.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 2.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism