Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for tfe3a+tfe3b

Z-value: 1.49

Motif logo

Transcription factors associated with tfe3a+tfe3b

Gene Symbol Gene ID Gene Info
ENSDARG00000019457 transcription factor binding to IGHM enhancer 3b
ENSDARG00000098903 transcription factor binding to IGHM enhancer 3a
ENSDARG00000111231 transcription factor binding to IGHM enhancer 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfe3bdr11_v1_chr11_+_25504215_255042150.372.1e-04Click!
tfe3adr11_v1_chr8_+_7778770_7778770-0.151.4e-01Click!

Activity profile of tfe3a+tfe3b motif

Sorted Z-values of tfe3a+tfe3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_31665836 23.14 ENSDART00000135411
ENSDART00000143914
si:ch211-106h4.12
chr16_+_23960933 22.55 ENSDART00000146077
apolipoprotein Eb
chr5_-_29534748 15.49 ENSDART00000159587

chr16_-_45178430 15.07 ENSDART00000165186
si:dkey-33i11.9
chr3_-_16784280 14.86 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
chr14_+_52571134 13.49 ENSDART00000166708
ribosomal protein L26
chr18_-_48517040 12.00 ENSDART00000143645
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr22_-_17677947 11.70 ENSDART00000139911
tight junction protein 3
chr20_-_17041025 11.66 ENSDART00000063764
si:dkey-5n18.1
chr16_+_23960744 11.35 ENSDART00000058965
apolipoprotein Eb
chr18_-_7539166 11.32 ENSDART00000133541
si:dkey-30c15.2
chr25_+_37443194 10.63 ENSDART00000163178
ENSDART00000190262
solute carrier family 10, member 3
chr21_-_25741096 10.15 ENSDART00000181756
claudin h
chr18_+_44703343 10.10 ENSDART00000131510
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr20_+_38257766 10.07 ENSDART00000147485
ENSDART00000149160
chemokine (C-C motif) ligand 38, duplicate 6
chr2_-_24069331 9.74 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
solute carrier family 12 (potassium/chloride transporter), member 7a
chr10_+_36662640 9.58 ENSDART00000063359
uncoupling protein 2
chr6_+_112579 9.49 ENSDART00000034505
adaptor-related protein complex 1, mu 2 subunit
chr12_-_3903886 9.34 ENSDART00000184214
ENSDART00000041082
glycerophosphodiester phosphodiesterase domain containing 3b
chr3_-_39488639 9.32 ENSDART00000161644
zgc:100868
chr18_-_1414760 9.13 ENSDART00000171881
peptidase D
chr3_-_39488482 9.06 ENSDART00000135192
zgc:100868
chr23_-_5719453 9.04 ENSDART00000033093
ladinin
chr13_-_214122 8.92 ENSDART00000169273
protein phosphatase 1, regulatory subunit 21
chr16_+_23961276 8.80 ENSDART00000192754
apolipoprotein Eb
chr3_+_42923275 8.66 ENSDART00000168228
transmembrane protein 184a
chr25_+_245438 8.40 ENSDART00000004689
zgc:92481
chr25_+_10547228 8.37 ENSDART00000067678
zgc:110339
chr9_-_56272465 8.34 ENSDART00000039235
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_15171435 8.30 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr19_+_791538 8.30 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr1_+_54766943 8.20 ENSDART00000144759
NLR family CARD domain containing 6
chr3_+_16922226 8.05 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr17_+_25331576 8.01 ENSDART00000157309
transmembrane protein 54a
chr13_-_36050303 8.01 ENSDART00000134955
ENSDART00000139087
legumain
chr10_-_35149513 8.01 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr19_+_19762183 8.00 ENSDART00000163611
ENSDART00000187604
homeobox A3a
chr1_+_14253118 7.99 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr19_+_19772765 7.99 ENSDART00000182028
ENSDART00000161019
homeobox A3a
chr7_+_49654588 7.98 ENSDART00000025451
ENSDART00000141934
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr5_+_27404946 7.96 ENSDART00000121886
ENSDART00000005025
hematopoietic death receptor
chr15_-_1198886 7.81 ENSDART00000063285
latexin
chr2_-_43545342 7.77 ENSDART00000179796

chr1_-_58059134 7.63 ENSDART00000160970
caspase b
chr19_+_48117995 7.62 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr11_+_24729346 7.50 ENSDART00000087740
zgc:153953
chr7_-_19923249 7.50 ENSDART00000078694
zgc:110591
chr6_-_40429411 7.34 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
chr8_+_30797363 7.28 ENSDART00000077280
matrix metallopeptidase 11a
chr11_+_10541258 7.27 ENSDART00000132365
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr24_-_42072886 7.16 ENSDART00000171389

chr7_+_39410180 7.12 ENSDART00000168641

chr5_+_26204561 7.09 ENSDART00000137178
MARVEL domain containing 2b
chr7_-_55633475 7.02 ENSDART00000149478
galactosamine (N-acetyl)-6-sulfatase
chr17_-_24916889 6.99 ENSDART00000156157
si:ch211-195o20.7
chr9_-_23944470 6.99 ENSDART00000138754
collagen, type VI, alpha 3
chr9_+_35077546 6.97 ENSDART00000142688
si:dkey-192g7.3
chr3_+_31662126 6.96 ENSDART00000113441
myosin, light chain kinase 5
chr24_+_42149453 6.90 ENSDART00000128766
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr23_+_384850 6.84 ENSDART00000114000
zgc:101663
chr18_-_6943577 6.84 ENSDART00000132399
si:dkey-266m15.6
chr21_-_22673758 6.75 ENSDART00000164910
grass carp reovirus (GCRV)-induced gene 2i
chr11_-_270210 6.73 ENSDART00000005217
ENSDART00000172779
aminolevulinate, delta-, synthase 1
chr10_+_41159241 6.65 ENSDART00000141657
annexin A4
chr11_-_42730063 6.63 ENSDART00000169776
si:ch73-106k19.2
chr20_-_32045057 6.58 ENSDART00000152970
ENSDART00000034248
RAB32a, member RAS oncogene family
chr17_+_30843881 6.57 ENSDART00000149600
ENSDART00000148547
tripeptidyl peptidase I
chr19_-_1947403 6.54 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr24_-_12938922 6.51 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr25_+_19718504 6.50 ENSDART00000036702
myxovirus (influenza virus) resistance D
chr17_+_6563307 6.50 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr12_-_44180132 6.48 ENSDART00000165998
si:ch73-329n5.1
chr16_+_19029297 6.45 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr23_+_43201142 6.41 ENSDART00000158832
ENSDART00000190315
si:dkey-65j6.2
chr23_+_43200911 6.39 ENSDART00000164262
si:dkey-65j6.2
chr17_+_32622933 6.38 ENSDART00000077418
cathepsin Ba
chr18_+_26422124 6.29 ENSDART00000060245
cathepsin H
chr2_+_36007449 6.21 ENSDART00000161837
laminin, gamma 2
chr8_+_25615781 6.17 ENSDART00000062385
solute carrier family 38, member 5a
chr1_+_12135129 6.16 ENSDART00000126020
serine peptidase inhibitor, Kazal type 4
chr9_-_34269066 6.16 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr3_-_3209432 6.15 ENSDART00000140635
si:ch211-229i14.2
chr15_+_20403903 6.13 ENSDART00000134182
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr15_-_43625549 6.12 ENSDART00000168589
cathepsin C
chr19_+_2590182 6.10 ENSDART00000162293
si:ch73-345f18.3
chr2_+_24507770 6.04 ENSDART00000154802
ENSDART00000052063
ribosomal protein S28
chr24_+_35564668 6.04 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr7_-_67214972 6.00 ENSDART00000156861
switching B cell complex subunit SWAP70a
chr4_-_992063 5.97 ENSDART00000181630
ENSDART00000183898
ENSDART00000160902
N-acetylgalactosaminidase, alpha
chr10_-_24724388 5.97 ENSDART00000148582
sphingomyelin phosphodiesterase 1, acid lysosomal
chr18_+_44649804 5.92 ENSDART00000059063
EH-domain containing 2b
chr7_+_39410393 5.87 ENSDART00000158561
ENSDART00000185173

chr10_+_36650222 5.87 ENSDART00000126963
uncoupling protein 3
chr23_+_26079467 5.87 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr18_-_7539469 5.85 ENSDART00000101296
si:dkey-30c15.2
chr5_+_4564233 5.82 ENSDART00000193435

chr8_-_31075015 5.76 ENSDART00000010993
solute carrier family 20, member 1a
chr9_-_33063083 5.74 ENSDART00000048550
si:ch211-125e6.5
chr15_-_47468085 5.71 ENSDART00000164438
inositol polyphosphate phosphatase-like 1a
chr5_-_1963498 5.58 ENSDART00000073462
ribosomal protein, large, P0
chr14_+_22076596 5.57 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr19_-_808265 5.56 ENSDART00000082454
glycosylated lysosomal membrane protein
chr22_+_29991834 5.52 ENSDART00000147728
si:dkey-286j15.3
chr18_-_48550426 5.46 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr22_+_5120033 5.45 ENSDART00000169200
muscle-specific beta 1 integrin binding protein
chr19_-_15229421 5.28 ENSDART00000055619
phosphatase and actin regulator 4a
chr3_+_14463941 5.12 ENSDART00000170927
calponin 1, basic, smooth muscle, b
chr15_+_46853252 5.12 ENSDART00000186040
zgc:153039
chr23_+_45910033 5.11 ENSDART00000165025
ATP-binding cassette, sub-family G (WHITE), member 2a
chr19_-_42503143 5.07 ENSDART00000007642
zgc:110239
chr7_-_59054322 5.05 ENSDART00000165390
charged multivesicular body protein 5b
chr15_-_4580763 5.04 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr6_+_392815 4.99 ENSDART00000163142
cytohesin 4b
chr4_+_60664235 4.98 ENSDART00000186182

chr8_+_13389115 4.89 ENSDART00000184428
ENSDART00000154266
ENSDART00000049469
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
chr1_+_58176023 4.88 ENSDART00000151051
si:ch211-15j1.7
chr19_+_19786117 4.86 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr7_-_3693303 4.77 ENSDART00000166949
si:ch211-282j17.13
chr23_+_35847200 4.77 ENSDART00000129222
retinoic acid receptor gamma a
chr20_-_39735952 4.72 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr12_+_20336070 4.72 ENSDART00000066385
zgc:163057
chr6_-_40651944 4.70 ENSDART00000187423
peptidylprolyl isomerase (cyclophilin)-like 1
chr5_+_50913034 4.69 ENSDART00000149787
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr10_-_15053507 4.69 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr25_+_22107643 4.68 ENSDART00000089680
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr21_-_10773344 4.68 ENSDART00000063244
gastrin-releasing peptide
chr15_-_43327911 4.66 ENSDART00000077386
protease, serine, 16 (thymus)
chr21_+_4540127 4.64 ENSDART00000043431
nucleoporin 188
chr17_+_32623931 4.63 ENSDART00000144217
cathepsin Ba
chr18_-_46280578 4.62 ENSDART00000131724
phospholipase D family, member 3
chr25_+_258883 4.60 ENSDART00000155256
zgc:92481
chr1_-_8140763 4.60 ENSDART00000091508
si:dkeyp-9d4.4
chr15_-_3277635 4.60 ENSDART00000189094
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr4_+_5341592 4.60 ENSDART00000123375
ENSDART00000067371
zgc:113263
chr10_+_5268054 4.60 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr21_+_7298687 4.60 ENSDART00000187746

chr7_-_35126374 4.59 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr2_-_10386738 4.58 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr7_-_11383933 4.57 ENSDART00000163949
mesoderm development LRP chaperone
chr12_+_37401331 4.57 ENSDART00000125040
si:ch211-152f22.4
chr23_+_39089574 4.56 ENSDART00000164711
nuclear factor of activated T cells 2a
chr19_+_19756425 4.52 ENSDART00000167606
homeobox A3a
chr5_-_23800376 4.52 ENSDART00000134184
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr10_-_21953643 4.51 ENSDART00000188921
ENSDART00000193569

chr3_-_18805225 4.51 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr16_+_33143503 4.49 ENSDART00000058471
ENSDART00000179385
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_50913357 4.45 ENSDART00000092938
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr19_-_1855368 4.43 ENSDART00000029646
ribosomal protein, large, P1
chr22_-_17653143 4.41 ENSDART00000089171
histocompatibility (minor) HA-1 b
chr25_+_31323978 4.36 ENSDART00000067030
lymphocyte-specific protein 1
chr7_-_3669868 4.34 ENSDART00000172907
si:ch211-282j17.12
chr14_+_39156 4.34 ENSDART00000082184
transmembrane protein 107
chr15_-_28596507 4.31 ENSDART00000156800
si:ch211-225b7.5
chr21_-_22715297 4.29 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr8_-_16650595 4.29 ENSDART00000135319
oxysterol binding protein-like 9
chr2_+_24507597 4.29 ENSDART00000133109
ribosomal protein S28
chr25_+_20188769 4.28 ENSDART00000142781
caldesmon 1b
chr5_+_51594209 4.25 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
creatine kinase, mitochondrial 2b (sarcomeric)
chr8_+_41229233 4.25 ENSDART00000131135
zgc:152830
chr19_+_47502581 4.24 ENSDART00000171526

chr11_+_45092866 4.21 ENSDART00000163408
si:dkey-93h22.8
chr23_-_26784736 4.21 ENSDART00000024064
ENSDART00000131615
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr6_+_7123980 4.20 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
chr24_-_18919562 4.12 ENSDART00000144244
ENSDART00000106188
ENSDART00000182518
carboxypeptidase A6
chr4_-_75930031 4.12 ENSDART00000170728
ENSDART00000181924
si:dkey-261j11.3
si:dkey-261j11.2
chr22_-_10165446 4.06 ENSDART00000142012
RanBP-type and C3HC4-type zinc finger containing 1
chr6_-_2154137 4.05 ENSDART00000162656
transglutaminase 5, like
chr21_-_3007412 4.04 ENSDART00000190839
zgc:86839
chr5_-_69944084 4.03 ENSDART00000188557
ENSDART00000127782
UDP glucuronosyltransferase 2 family, polypeptide A4
chr9_+_55857193 4.02 ENSDART00000160980
septin 10
chr23_+_10146542 4.01 ENSDART00000048073
zgc:171775
chr18_-_11729 4.00 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr19_+_34169055 3.96 ENSDART00000135592
ENSDART00000186043
POC1 centriolar protein homolog B (Chlamydomonas), like
chr8_+_8671229 3.96 ENSDART00000131963
ubiquitin specific peptidase 11
chr13_-_280652 3.96 ENSDART00000193627
solute carrier family 30 (zinc transporter), member 6
chr21_-_3700334 3.94 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr25_+_29474982 3.94 ENSDART00000130410
interleukin 17 receptor E-like
chr11_-_42472941 3.92 ENSDART00000166624
ADP-ribosylation factor 4b
chr23_+_13814978 3.90 ENSDART00000090864
leiomodin 3 (fetal)
chr7_-_11384279 3.89 ENSDART00000102515
ENSDART00000172796
mesoderm development LRP chaperone
chr14_+_23709543 3.89 ENSDART00000136909
glucosamine-6-phosphate deaminase 1
chr21_-_22669669 3.76 ENSDART00000101784
grass carp reovirus (GCRV)-induced gene 2j
chr3_-_4591643 3.73 ENSDART00000138144
finTRIM family, member 50
chr20_-_37813863 3.72 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr15_+_20403084 3.71 ENSDART00000141388
ENSDART00000152734
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr15_+_1199407 3.67 ENSDART00000163827
major facilitator superfamily domain containing 1
chr9_+_37152564 3.65 ENSDART00000189497
GLI family zinc finger 2a
chr6_+_7490154 3.63 ENSDART00000014892
erb-b2 receptor tyrosine kinase 3a
chr8_+_21195420 3.62 ENSDART00000100234
ENSDART00000091307
collagen, type II, alpha 1a
chr8_+_20438884 3.61 ENSDART00000016422
ENSDART00000133794
MAP kinase interacting serine/threonine kinase 2b
chr3_-_8765165 3.60 ENSDART00000191131

chr1_-_59139599 3.58 ENSDART00000152233
si:ch1073-110a20.3
chr13_+_7049210 3.58 ENSDART00000168608
ENSDART00000128675
ENSDART00000164789
ribonuclease T2
chr24_+_7631797 3.58 ENSDART00000187464
caveolae associated protein 1b
chr14_+_16765992 3.58 ENSDART00000140061
sequestosome 1
chr23_+_35847538 3.56 ENSDART00000143935
retinoic acid receptor gamma a
chr13_+_22717366 3.53 ENSDART00000134122
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr21_-_7265219 3.51 ENSDART00000158852
EGF-like-domain, multiple 7
chr24_+_27511734 3.50 ENSDART00000105771
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr21_-_45891262 3.50 ENSDART00000169816
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a+tfe3b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.2 42.7 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
3.3 23.2 GO:0060017 parathyroid gland development(GO:0060017)
2.7 8.0 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
2.0 8.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
2.0 8.0 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.7 8.5 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
1.6 9.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
1.6 4.9 GO:0001779 natural killer cell differentiation(GO:0001779)
1.6 6.5 GO:0071548 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
1.5 6.2 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
1.5 4.6 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
1.5 12.2 GO:1990845 adaptive thermogenesis(GO:1990845)
1.5 6.0 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
1.2 11.7 GO:0030104 water homeostasis(GO:0030104)
1.1 3.4 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
1.0 2.9 GO:0035973 aggrephagy(GO:0035973)
1.0 2.9 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.9 4.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.9 3.6 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.9 2.7 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.9 2.7 GO:0006004 fucose metabolic process(GO:0006004)
0.9 2.6 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.9 6.0 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.8 3.4 GO:0015865 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.8 5.7 GO:0090024 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.8 4.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.8 2.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.8 2.3 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.8 10.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.8 5.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.7 7.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 15.2 GO:0032438 melanosome organization(GO:0032438)
0.7 5.0 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 2.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.7 3.5 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.7 2.7 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.7 4.6 GO:0034650 cortisol metabolic process(GO:0034650)
0.6 3.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.6 8.1 GO:0001845 phagolysosome assembly(GO:0001845)
0.6 16.0 GO:0006884 cell volume homeostasis(GO:0006884)
0.6 1.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.5 3.2 GO:0006013 mannose metabolic process(GO:0006013)
0.5 1.6 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.5 5.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.5 0.5 GO:0048753 pigment granule organization(GO:0048753)
0.5 7.6 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.5 7.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.5 14.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.4 10.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 3.6 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.4 3.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 4.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.4 4.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 6.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.4 8.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.4 1.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.4 8.3 GO:0051639 actin filament network formation(GO:0051639)
0.4 8.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 3.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.3 6.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.3 6.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 3.4 GO:0090148 membrane fission(GO:0090148)
0.3 3.6 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 4.6 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.3 4.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 0.9 GO:1903358 regulation of Golgi organization(GO:1903358)
0.3 2.5 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.3 2.8 GO:0007220 Notch receptor processing(GO:0007220)
0.3 3.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.3 13.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 4.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 4.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.3 2.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 7.6 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.3 0.9 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3 1.7 GO:0098773 skin epidermis development(GO:0098773)
0.3 2.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3 3.5 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.3 4.5 GO:0030259 lipid glycosylation(GO:0030259)
0.3 1.3 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.3 1.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 14.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 1.9 GO:0006517 protein deglycosylation(GO:0006517)
0.2 1.7 GO:0007141 male meiosis I(GO:0007141)
0.2 7.4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.2 4.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.2 2.6 GO:0000266 mitochondrial fission(GO:0000266)
0.2 2.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.7 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.2 0.7 GO:0071514 genetic imprinting(GO:0071514)
0.2 1.3 GO:0007343 egg activation(GO:0007343)
0.2 4.7 GO:0015671 oxygen transport(GO:0015671)
0.2 3.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 3.6 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 3.1 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.2 2.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.3 GO:0055016 hypochord development(GO:0055016)
0.2 4.7 GO:0001966 thigmotaxis(GO:0001966)
0.2 6.9 GO:0060037 pharyngeal system development(GO:0060037)
0.2 7.5 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 2.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 3.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.6 GO:0021588 cerebellum formation(GO:0021588)
0.2 4.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 4.2 GO:0008272 sulfate transport(GO:0008272)
0.2 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.9 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2 6.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 1.3 GO:0002312 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.2 2.6 GO:0060021 palate development(GO:0060021)
0.2 1.1 GO:0021561 facial nerve development(GO:0021561)
0.2 2.4 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 2.8 GO:0070527 platelet aggregation(GO:0070527)
0.2 2.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 2.6 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.2 3.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 2.9 GO:0015693 magnesium ion transport(GO:0015693)
0.2 2.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 2.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 5.6 GO:0045332 phospholipid translocation(GO:0045332)
0.2 1.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 1.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 3.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 6.4 GO:0032456 endocytic recycling(GO:0032456)
0.2 1.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 1.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 3.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 10.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 9.9 GO:0001570 vasculogenesis(GO:0001570)
0.1 9.6 GO:0051607 defense response to virus(GO:0051607)
0.1 5.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 2.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 1.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.9 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 2.5 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.4 GO:0043476 pigment accumulation(GO:0043476)
0.1 7.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 5.6 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 1.6 GO:0048264 determination of ventral identity(GO:0048264)
0.1 1.8 GO:0042026 protein refolding(GO:0042026)
0.1 2.6 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 2.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 3.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 6.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 4.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 8.0 GO:0051170 nuclear import(GO:0051170)
0.1 3.0 GO:0060030 dorsal convergence(GO:0060030)
0.1 8.2 GO:0031101 fin regeneration(GO:0031101)
0.1 0.4 GO:0097037 heme export(GO:0097037)
0.1 2.4 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 7.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 7.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 12.2 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.1 6.1 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 3.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 1.0 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.2 GO:0060623 regulation of sister chromatid cohesion(GO:0007063) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 2.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 2.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 6.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 1.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0017145 stem cell division(GO:0017145)
0.1 2.2 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 1.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 2.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.0 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.1 1.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.8 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 1.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 4.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.8 GO:0007569 cell aging(GO:0007569)
0.1 0.4 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 4.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 2.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 1.3 GO:0008643 carbohydrate transport(GO:0008643)
0.1 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.2 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.8 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 2.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.3 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 2.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 1.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 2.6 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 26.6 GO:0006508 proteolysis(GO:0006508)
0.0 1.4 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 2.1 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.7 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.2 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.8 GO:0006814 sodium ion transport(GO:0006814)
0.0 2.0 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.6 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.1 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0007168 cGMP biosynthetic process(GO:0006182) receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.9 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 1.4 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.9 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.4 GO:0051225 spindle assembly(GO:0051225)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 42.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
3.4 10.3 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
1.9 7.6 GO:0061702 inflammasome complex(GO:0061702)
1.7 5.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.2 3.6 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
1.2 4.6 GO:0044611 nuclear pore inner ring(GO:0044611)
1.0 5.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.9 3.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.8 3.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.7 8.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7 2.8 GO:0031085 BLOC-3 complex(GO:0031085)
0.7 2.6 GO:0098842 postsynaptic early endosome(GO:0098842)
0.6 2.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.5 3.6 GO:0016234 inclusion body(GO:0016234)
0.5 9.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 1.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 3.5 GO:0030428 cell septum(GO:0030428)
0.4 1.7 GO:0005880 nuclear microtubule(GO:0005880)
0.4 2.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 4.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 2.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.4 2.3 GO:1902636 kinociliary basal body(GO:1902636)
0.4 9.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 2.6 GO:0035101 FACT complex(GO:0035101)
0.3 2.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 6.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 3.0 GO:0071797 LUBAC complex(GO:0071797)
0.3 0.9 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.3 5.6 GO:0042555 MCM complex(GO:0042555)
0.3 4.6 GO:0070187 telosome(GO:0070187)
0.3 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 5.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 4.3 GO:0036038 MKS complex(GO:0036038)
0.3 2.1 GO:0032797 SMN complex(GO:0032797)
0.2 1.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.2 11.2 GO:0032587 ruffle membrane(GO:0032587)
0.2 64.6 GO:0005764 lysosome(GO:0005764)
0.2 1.0 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.2 2.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 2.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 3.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 4.5 GO:0005771 multivesicular body(GO:0005771)
0.2 11.0 GO:0031901 early endosome membrane(GO:0031901)
0.2 6.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 23.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 0.8 GO:0070209 ASTRA complex(GO:0070209)
0.2 4.0 GO:0031430 M band(GO:0031430)
0.2 8.6 GO:0031941 filamentous actin(GO:0031941)
0.2 3.6 GO:0009925 basal plasma membrane(GO:0009925)
0.2 1.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 10.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 9.6 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 1.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 2.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 10.6 GO:0005581 collagen trimer(GO:0005581)
0.1 1.3 GO:0014704 intercalated disc(GO:0014704)
0.1 4.8 GO:0030496 midbody(GO:0030496)
0.1 0.7 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 4.7 GO:0030175 filopodium(GO:0030175)
0.1 3.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 2.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 3.4 GO:0016342 catenin complex(GO:0016342)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.8 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 1.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0070652 HAUS complex(GO:0070652)
0.1 4.4 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.1 4.1 GO:0005769 early endosome(GO:0005769)
0.1 2.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 16.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 6.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 42.5 GO:0005615 extracellular space(GO:0005615)
0.0 3.4 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 12.8 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 5.0 GO:0043292 myofibril(GO:0030016) contractile fiber(GO:0043292)
0.0 0.7 GO:0008278 cohesin complex(GO:0008278)
0.0 1.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 7.8 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 10.8 GO:0005739 mitochondrion(GO:0005739)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0000502 proteasome complex(GO:0000502)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.7 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.2 42.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
3.9 15.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
2.4 7.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
2.3 6.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.2 6.7 GO:0016748 succinyltransferase activity(GO:0016748)
2.2 6.6 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
2.0 8.0 GO:0005153 interleukin-8 receptor binding(GO:0005153)
2.0 6.0 GO:0004557 alpha-galactosidase activity(GO:0004557)
1.8 10.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.3 5.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.2 17.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.2 6.0 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
1.1 5.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
1.0 4.0 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.9 2.8 GO:0070051 fibrinogen binding(GO:0070051)
0.9 2.8 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.9 2.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.9 5.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.9 3.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.9 2.7 GO:0042806 fucose binding(GO:0042806)
0.9 3.5 GO:0004903 growth hormone receptor activity(GO:0004903)
0.8 3.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.8 5.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.8 2.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 3.6 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.7 2.2 GO:0003913 DNA photolyase activity(GO:0003913)
0.7 2.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.6 2.6 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.6 16.0 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.6 7.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.6 3.1 GO:0004565 beta-galactosidase activity(GO:0004565) galactosidase activity(GO:0015925)
0.6 4.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.6 7.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 7.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 7.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.6 3.4 GO:0042169 SH2 domain binding(GO:0042169)
0.6 3.3 GO:0017040 ceramidase activity(GO:0017040)
0.5 2.6 GO:0008097 5S rRNA binding(GO:0008097)
0.5 4.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.5 1.5 GO:0034618 arginine binding(GO:0034618)
0.5 6.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.5 12.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 2.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 9.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 3.5 GO:0004100 chitin synthase activity(GO:0004100)
0.4 3.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 9.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 2.0 GO:0070412 R-SMAD binding(GO:0070412)
0.4 4.7 GO:0031720 haptoglobin binding(GO:0031720)
0.4 4.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 1.5 GO:0070513 death domain binding(GO:0070513)
0.4 2.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 3.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3 3.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 4.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.3 4.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3 3.4 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 4.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 0.9 GO:0019777 Atg12 transferase activity(GO:0019777)
0.3 13.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 10.8 GO:0030145 manganese ion binding(GO:0030145)
0.3 1.3 GO:0050699 WW domain binding(GO:0050699)
0.3 1.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.3 7.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 4.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 3.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 4.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 1.0 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.2 1.0 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.4 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 1.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 3.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 4.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 3.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 4.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.2 31.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 3.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 3.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 3.9 GO:0003785 actin monomer binding(GO:0003785)
0.2 3.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 4.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 5.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.9 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 4.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 5.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 2.4 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.2 1.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.2 4.3 GO:0015248 sterol transporter activity(GO:0015248)
0.2 3.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 4.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 15.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 6.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.3 GO:0008296 deoxyribonuclease I activity(GO:0004530) 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 2.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 27.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.7 GO:2001069 glycogen binding(GO:2001069)
0.1 1.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 6.1 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 5.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 7.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 4.1 GO:0019213 deacetylase activity(GO:0019213)
0.1 14.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.5 GO:0043531 ADP binding(GO:0043531)
0.1 5.4 GO:0003823 antigen binding(GO:0003823)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 2.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 3.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 5.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.7 GO:0051087 chaperone binding(GO:0051087)
0.1 0.5 GO:1903924 estradiol binding(GO:1903924)
0.1 0.3 GO:0008430 selenium binding(GO:0008430)
0.1 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 4.7 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 11.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 1.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 3.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 10.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 4.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 4.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 4.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 12.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 4.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 3.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 17.2 GO:0005525 GTP binding(GO:0005525)
0.0 1.2 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 2.5 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:1900750 oligopeptide binding(GO:1900750)
0.0 3.8 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.9 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 3.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.3 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 5.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 3.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.7 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 23.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 6.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 4.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 4.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 3.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 3.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 14.6 PID TNF PATHWAY TNF receptor signaling pathway
0.3 6.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 4.6 ST GA13 PATHWAY G alpha 13 Pathway
0.2 7.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 10.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 18.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.7 PID AURORA A PATHWAY Aurora A signaling
0.1 3.0 PID SHP2 PATHWAY SHP2 signaling
0.1 2.4 PID ATR PATHWAY ATR signaling pathway
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.2 PID MYC PATHWAY C-MYC pathway
0.1 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.1 PID P73PATHWAY p73 transcription factor network
0.1 2.3 PID EPO PATHWAY EPO signaling pathway
0.1 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.7 8.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.6 8.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.5 7.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.5 5.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 7.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4 4.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 4.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.4 4.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 12.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 34.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 6.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 11.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.3 15.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 15.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.2 1.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 5.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 3.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 7.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 7.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 10.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.2 6.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 8.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 4.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 6.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 3.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 5.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 5.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.8 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 6.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.8 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 5.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins