ISMARA results: tfe3a+tfe3b

Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation

Downloads

Results for tfe3a+tfe3b

Z-value: 1.49

Motif logo

Transcription factors associated with tfe3a+tfe3b

Gene Symbol	Gene ID	Gene Info
tfe3b NCBI UniProt	ENSDARG00000019457	transcription factor binding to IGHM enhancer 3b
tfe3a NCBI UniProt	ENSDARG00000098903	transcription factor binding to IGHM enhancer 3a
tfe3b NCBI UniProt	ENSDARG00000111231	transcription factor binding to IGHM enhancer 3b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
tfe3b	dr11_v1_chr11_+_25504215_25504215	0.37	2.1e-04	Click!
tfe3a	dr11_v1_chr8_+_7778770_7778770	-0.15	1.4e-01	Click!

Activity profile of tfe3a+tfe3b motif

Sorted Z-values of tfe3a+tfe3b motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_31665836 Show fit	23.14	ENSDART00000135411 ENSDART00000143914	si:ch211-106h4.12 NCBI UniProt Show fit	si:ch211-106h4.12
chr16_+_23960933 Show fit	22.55	ENSDART00000146077	apoeb NCBI UniProt Show fit	apolipoprotein Eb
chr5_-_29534748 Show fit	15.49	ENSDART00000159587	AL831768.1 NCBI UniProt Show fit
chr16_-_45178430 Show fit	15.07	ENSDART00000165186	si:dkey-33i11.9 NCBI UniProt Show fit	si:dkey-33i11.9
chr3_-_16784280 Show fit	14.86	ENSDART00000137108 ENSDART00000137276	si:dkey-30j10.5 NCBI UniProt Show fit	si:dkey-30j10.5
chr14_+_52571134 Show fit	13.49	ENSDART00000166708	rpl26 NCBI UniProt Show fit	ribosomal protein L26
chr18_-_48517040 Show fit	12.00	ENSDART00000143645	kcnj1a.3 NCBI UniProt Show fit	potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr22_-_17677947 Show fit	11.70	ENSDART00000139911	tjp3 NCBI UniProt Show fit	tight junction protein 3
chr20_-_17041025 Show fit	11.66	ENSDART00000063764	si:dkey-5n18.1 NCBI UniProt Show fit	si:dkey-5n18.1
chr16_+_23960744 Show fit	11.35	ENSDART00000058965	apoeb NCBI UniProt Show fit	apolipoprotein Eb

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a+tfe3b

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
14.2	42.7	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0	26.6	GO:0006508	proteolysis(GO:0006508)
3.3	23.2	GO:0060017	parathyroid gland development(GO:0060017)
0.6	16.0	GO:0006884	cell volume homeostasis(GO:0006884)
0.7	15.2	GO:0032438	melanosome organization(GO:0032438)
0.5	14.4	GO:0044243	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3	14.2	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.3	13.2	GO:0048247	lymphocyte chemotaxis(GO:0048247)
1.5	12.2	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	12.2	GO:0070507	regulation of microtubule cytoskeleton organization(GO:0070507)

Showing 1 to 10 of 244 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	64.6	GO:0005764	lysosome(GO:0005764)
10.7	42.7	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	42.5	GO:0005615	extracellular space(GO:0005615)
0.2	23.8	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	16.7	GO:0000139	Golgi membrane(GO:0000139)
0.0	12.8	GO:0031966	mitochondrial membrane(GO:0031966)
0.2	11.2	GO:0032587	ruffle membrane(GO:0032587)
0.2	11.0	GO:0031901	early endosome membrane(GO:0031901)
0.0	10.8	GO:0005739	mitochondrion(GO:0005739)
0.1	10.6	GO:0005581	collagen trimer(GO:0005581)

Showing 1 to 10 of 113 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
14.2	42.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	31.3	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	27.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.2	17.5	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	17.2	GO:0005525	GTP binding(GO:0005525)
0.6	16.0	GO:0015379	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
3.9	15.5	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	15.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	14.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.3	13.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)

Showing 1 to 10 of 201 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	23.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	18.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3	14.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	10.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	7.0	NABA COLLAGENS	Genes encoding collagen proteins
0.5	6.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.3	6.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
1.0	4.9	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.3	4.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	4.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network

Showing 1 to 10 of 36 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	34.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.3	15.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.2	15.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.3	12.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.3	11.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.2	10.9	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.9	9.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6	8.4	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.2	8.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.7	8.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR

Showing 1 to 10 of 61 entries

Results for tfe3a+tfe3b

Z-value: 1.49

Motif logo

Transcription factors associated with tfe3a+tfe3b

Activity-expression correlation:

Activity profile of tfe3a+tfe3b motif

Sorted Z-values of tfe3a+tfe3b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a+tfe3b

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: